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	Fusion Gene Summary
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Fusion gene:CLIC1-NUDT3 (FusionGDB2 ID:HG1192TG11165)

Fusion Gene Summary for CLIC1-NUDT3

Fusion gene summary

Fusion gene information	Fusion gene name: CLIC1-NUDT3
	Fusion gene ID: hg1192tg11165
		Hgene	Tgene
	Gene symbol	CLIC1	NUDT3
	Gene ID	1192	11165
	Gene name	chloride intracellular channel 1	nudix hydrolase 3
	Synonyms	CL1C1\|CLCNL1\|G6\|NCC27	DIPP\|DIPP-1\|DIPP1
	Cytomap	('CLIC1')('NUDT3') 6p21.33	6p21.31
	Type of gene	protein-coding	protein-coding
	Description	chloride intracellular channel protein 1RNCC proteinchloride channel ABPhRNCCnuclear chloride ion channel 27nuclear chloride ion channel proteinp64CLCPregulatory nuclear chloride ion channel protein	diphosphoinositol polyphosphate phosphohydrolase 1diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1nucleoside diphosphate-linked moiety X motif 3nudix (nucleoside diphosphate linked moiety X)-type motif 3nudix motif 3
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000375779, ENST00000375784, ENST00000375780, ENST00000395892, ENST00000383404, ENST00000383405, ENST00000400052, ENST00000400058, ENST00000415179, ENST00000418285, ENST00000420458, ENST00000422167, ENST00000423055, ENST00000423143, ENST00000423804, ENST00000425464, ENST00000431921, ENST00000433916, ENST00000434202, ENST00000435242, ENST00000438708, ENST00000438750, ENST00000442045, ENST00000447338, ENST00000447369, ENST00000451546, ENST00000456863, ENST00000457485,
Fusion gene scores	* DoF score	5 X 5 X 4=100	13 X 7 X 8=728
	# samples	6	15
	** MAII score	log2(6/100*10)=-0.736965594166206 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(15/728*10)=-2.27897594970282 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: CLIC1 [Title/Abstract] AND NUDT3 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	CLIC1(31701343)-NUDT3(34263462), # samples:2
Anticipated loss of major functional domain due to fusion event.	CLIC1-NUDT3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CLIC1-NUDT3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CLIC1-NUDT3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CLIC1-NUDT3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	CLIC1	GO:0006821	chloride transport	9139710
Tgene	NUDT3	GO:0071544	diphosphoinositol polyphosphate catabolic process	10585413

Fusion gene breakpoints across CLIC1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across NUDT3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	SKCM	TCGA-BF-AAP4-01A	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-

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Fusion Gene ORF analysis for CLIC1-NUDT3

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
Frame-shift	ENST00000375779	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
Frame-shift	ENST00000375784	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
In-frame	ENST00000375780	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
In-frame	ENST00000395892	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000383404	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000383405	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000400052	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000400058	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000415179	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000418285	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000420458	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000422167	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000423055	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000423143	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000423804	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000425464	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000431921	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000433916	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000434202	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000435242	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000438708	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000438750	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000442045	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000447338	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000447369	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000451546	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000456863	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-
intron-3CDS	ENST00000457485	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000375780	CLIC1	chr6	31701343	-	ENST00000607016	NUDT3	chr6	34263462	-	10338	955	910	461	149
ENST00000395892	CLIC1	chr6	31701343	-	ENST00000607016	NUDT3	chr6	34263462	-	9975	592	192	635	147

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000375780	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-	0.008217408	0.99178255
ENST00000395892	ENST00000607016	CLIC1	chr6	31701343	-	NUDT3	chr6	34263462	-	0.008047046	0.99195296

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Fusion Genomic Features for CLIC1-NUDT3

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

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Fusion Protein Features for CLIC1-NUDT3

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:31701343/chr6:34263462)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000375779

2_90

127

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000375780

2_90

127

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000375784

2_90

127

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000395892

2_90

127

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000375779

26_46

127

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000375780

26_46

127

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000375784

26_46

127

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000395892

26_46

127

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Tgene

NUDT3

chr6:31701343

chr6:34263462

ENST00000607016

89_91

173.0

Region

Substrate binding

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000375779

93_233

127

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000375780

93_233

127

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000375784

93_233

127

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000383404

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000383405

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000395892

93_233

127

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000400052

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000400058

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000415179

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000418285

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000420458

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000422167

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000423055

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000423143

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000423804

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000425464

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000431921

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000433916

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000434202

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000435242

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000438708

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000438750

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000442045

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000447338

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000447369

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000451546

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000456863

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000457485

93_233

242.0

Domain

Note=GST C-terminal

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000383404

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000383405

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000400052

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000400058

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000415179

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000418285

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000420458

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000422167

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000423055

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000423143

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000423804

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000425464

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000431921

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000433916

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000434202

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000435242

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000438708

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000438750

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000442045

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000447338

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000447369

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000451546

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000456863

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000457485

2_90

242.0

Region

Note=Required for insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000383404

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000383405

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000400052

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000400058

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000415179

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000418285

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000420458

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000422167

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000423055

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000423143

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000423804

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000425464

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000431921

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000433916

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000434202

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000435242

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000438708

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000438750

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000442045

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000447338

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000447369

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000451546

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000456863

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Hgene

CLIC1

chr6:31701343

chr6:34263462

ENST00000457485

26_46

242.0

Transmembrane

Helical%3B Note%3DAfter insertion into the membrane

Tgene

NUDT3

chr6:31701343

chr6:34263462

ENST00000607016

17_142

173.0

Domain

Nudix hydrolase

Tgene

NUDT3

chr6:31701343

chr6:34263462

ENST00000607016

51_72

173.0

Motif

Note=Nudix box

Tgene

NUDT3

chr6:31701343

chr6:34263462

ENST00000607016

18_20

173.0

Region

Substrate binding

Tgene

NUDT3

chr6:31701343

chr6:34263462

ENST00000607016

39_41

173.0

Region

Substrate binding

Top

Fusion Gene Sequence for CLIC1-NUDT3

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>17112_17112_1_CLIC1-NUDT3_CLIC1_chr6_31701343_ENST00000375780_NUDT3_chr6_34263462_ENST00000607016_length(transcript)=10338nt_BP=955nt
CCAAGTAGCTGGGATTACAGGTGCCCACCACCCCGCCTGGCAAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGTC
TGGTCTTGACTCCCTGACCTCAGGTGATCCACCCCCCTTGGCCTCCTAAAGTGTTGGGATTACAGGCGTGAGCCACCTCACCCGGCCCCT
AACTCTATTTCCTATGCCCAATCCCAAGTGTAGGCCACAAGGACTGCAAGTCCTAGTGCTGAGCTGGGCCCGGAGACAGTAGACTGCGGG
GGGCACAGGACCTACTGAGACACCAGTCTGGGCAGCTCAGGGAGTGCTGGCGTCACCCCTTCCCTAATCCCAGGCTGCATGGCTAACGGT
TCCTATCTGCAGTCCCAGCCTTCCACTTCCGAGTTCTTCTCTCAGACCACAGTCCCAGCAACCCAGAATTTGGATTGGAGTCTGGAAGAA
ATGCAGAATGATTAAACGACCACCTTTCCATTTGAAGTCCCCATCCCTGAATCTTCACGGGTGTGCCCAAGCTCCCCTCCCAGTTCCCCC
AGGGACGGCCACTTCCTGGTCCCCGACGCAACCATGGCTGAAGAACAACCGCAGGTCGAATTGTTCGTGAAGGCTGGCAGTGATGGGGCC
AAGATTGGGAACTGCCCATTCTCCCAGAGACTGTTCATGGTACTGTGGCTCAAGGGAGTCACCTTCAATGTTACCACCGTTGACACCAAA
AGGCGGACCGAGACAGTGCAGAAGCTGTGCCCAGGGGGGCAGCTCCCATTCCTGCTGTATGGCACTGAAGTGCACACAGACACCAACAAG
ATTGAGGAATTTCTGGAGGCAGTGCTGTGCCCTCCCAGGTACCCCAAGCTGGCAGCTCTGAACCCTGAGTCCAACACAGCTGGGCTGGAC
ATATTTGCCAAATTTTCTGCCTACATCAAGAATTCAAACCCAGCACTCAATGACAGCTGGAGTAAAAGGGACATTGGGAAGATTAGTTGG
AATTTTTGAGAACCAGGAGAGGAAGCACAGGACGTATGTCTATGTGCTCATTGTCACTGAAGTGCTGGAAGACTGGGAAGATTCAGTTAA
CATTGGAAGGAAGAGGGAATGGTTTAAAATAGAAGACGCCATAAAAGTGCTGCAGTATCACAAACCCGTGCAGGCATCATATTTTGAAAC
ATTGAGGCAAGGCTACTCAGCCAACAATGGCACCCCAGTCGTGGCCACCACATACTCGGTTTCTGCTCAGAGCTCGATGTCAGGCATCAG
ATGACTGAAGACTTCCTGTAAGAGAAATGGAAATTGGAAACTAGACTGAAGTGCAAATCTTCCCTCTCACCCTGGCTCTTTCCACTTCTC
ACAGGCCTCCTCTTTCAAATAAGGCATGGTGGGCAGCAAAGAAAGGGTGTATTGATAATGTTGCTGTTTGGTGTTAAGTGATGGGGCTTT
TTCTTCTGTTTTTATTGAGGGTGGGGGTTGGGTGTGTAATTTGTAAGTACTTTTGTGCATGATCTGTCCCTCCCTCTTCCCACCCCTGCA
GTCCTCTGAAGAGAGGCCAACAGCCTTCCCCTGCCTTGGATTCTGAAGTGTTCCTGTTTGTCTTATCCTGGCCCTGGCCAGACGTTTTCT
TTGATTTTTAATTTTTTTTTTTTATTAAAAGATACCAGTATGAGATGAAAACTTCCAATAATTTGTCCTATAATGTGCTGTACAGTTCAG
TAGAGTGGTCACTTTCACTGCAGTATACATTTATCTACACATTATATATCGGACATATAATATGTAAATAAATGACTTCTAGAAAGAGAA
ATTTGTTTAATTTTTCAAGGTTTTTTTCTCTTTTAATTTGGGCATTTCTAGAATTGAGAGCCTCACAATTAACATACCTTTTTGTTTTCG
ATGCTAGTGGCTGGGCAGGTTGCCCTGTCCTTTCTCTATTTCCCAGTCATTGACTGTAGATATGGGAAGAGTTTAGCTACCTTCATAGTG
CTCCCAGGACTCATGGCCTTTCCTTCTTTAAGCTGTATTTCCCTGCCCAGAAAGAAACAGGAAGAAACCTTTTTTTATTTTTTTATTTTT
TTTTAACCAAGCAAGGAGCAAATGGCCTCAGCCCAGATCTGTAAAAACAATGATAGAAATTGAATTCTGCCCCACATGTTGACAGTAGAG
TTGGAACTGGATTCTTGGGATTACTTATCTAAAAAACTGGAGCATCAGGTCCATTTCTGTTCTGCTGGTTTGGAATCTTTTCCGTAATGC
TATTTATTGCCAACAATGGCCTCTCTTTGTGTCCATATATGCCTTACACCGTGCTGACCTGGGTATCATCCATGTGCTCTGAAGCATCCA
ACTTTACTTTGCAGGTGCATCAATGTAGTCCTGTCCCTGAACTGAGTAACCGTGTTCCTGAAAAGTACACTAGGGAAATTCACCTGCTTG
CTTGTCTTTGTATTGGCATGGCACTTGTGATTGCACCATGGAGCATGCTCAGAGCTATTAAATTGGTCTCCCATCTCCCACCAGGATATG
AAAGGTCCATATGGGAGGCCACGTAATCACTTATTACAGTGGTTACATAATACACTGGCTCACTGCAGACTCTCTTGTTTTTTGATACAG
TTTCGTGCTGGCTTCATTTGCCAATTGTGTTGTTTAGTTCGGAAGTAAGAGGGTCTTGAGATTGAGGGGTAGGGAGGGCTACACTGACTG
ATCCGTGGCTTAAGACAGGAGATTATCTCTGTACTCCAGTGGCATCTCCTTAGCCAAGATGTGAAATTAAAATCATAGTTCGCCTCATTT
AAAAATTCTAATAAAGCACTCAAACTTTGAAAAGCTTTTACTTTTCCCTCCTACTAAAAGAAATGTATGTACCTCATAGCCCTGTGTCAT
TTAGTGTTCAGCACTTTTGGGAACATCAGTTGGTGAACTTTAAATTTTGCTGTCTACTCACTGGGCACGGTGGCTCACACCTGTAATCCC
AGCACTTTGGGAGGCTGAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGACCAACATGGTGAAACCCCGTCTCTACTAA
AAATGCAGAAATTAGGTGGGCGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCGAGATAATCGCTTGAACCTGGGAGGCAGAGGTTGCA
GTGAGCCGAGATTGCACCACTGTCGTCCAGCCTGGGTGATAAGAGTGAAACTCCATCTCAAAAAAAAAAAAAAAAAATTTTTTTTTTTTT
TTTTGCTATATACTCTTAGTTTACATCCTCTCCCCCAATCTTCACACACAGAGCCAAAGAGCAGTTATATTCTTGGGATACCATGATACC
TCTGGGAAAGGAATTATATTCCCAAGGAGAGGTCCCATTGGATAAGAACAATACCATGGGACTTGAGTCTGAATGCCAACTTACTATTCA
CACATCCTTCTTAAAAACGAACACACTGTTTCTTTTCCTGACCTAGAGCATTCTAAAGTTCTGTTCAAATAAATAAAGGGCAAAATAAAG
TAGATTTAACCAAGTGCCAGGTGGAATTCAAAAAACACATTCTTCCAGATAAATTCTACCTTTATGGTATGGATTTGAAAGTACTTTGCA
GGAAAACAGTCAGTACTCTTTAAAAAGGGACTGCAGGGCTGGGTGTAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCA
GGTGGGTCACTTGAGGCCAGGAGTTTGAGACCAGCCTGACCAACATGGCAAAACCCCATCTCTACTAAAATACAAAAATTAGCTGGGCAT
GATGGTGCACTCCTGTAATCCCAGCTACTTGGTAGGCTGAAGCATGAGAATTGCTTAAACCTGGGAGGCAGAGGTTGCAGTAAGCCAAGA
TCATGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTTAATAAATAAATAAGAAAATAAAACGGAACTGCAGTGCTAACAG
TAATTTATACATTTTTAAATGTTCTGAGTATGTTTTGACTGGGCTAGTGTAACAATATACTACCCTGAAAGTGCAGTTTTGATTGTTGTT
GGTGTCTTTGGGTCAGGAAAGTGAACTGTGCCAAGAAGTATTTTTCAGTGACATGAATGGATTCCTGTTAATGCAATTGACTGAGAGATT
GTGCTTACGCTTTCTTAACTGACAAAAAGAGGCTTTGTCCAACATCAGAATTGTTGAAACTGGTGCTGTTTTCTGTTGCACTGGGATTCT
GATGATCTGGGATTTTCCCTCCTTGGCACAGTAAACACCATGACTGTCTTTATTGAGAATGTCGTCACAGTCCTTTAGTGATAGATTAGT
TAGACCCATGGTTGCAATACCTTTATCTCCCCAAAGAAAATAATCAAAAGAAAGCACAAAAGCTACCCTGTTTGCAGAATATTTCACTGA
CATTGATTTGTCATTAATTCTACCAGAGCTGACCTCATTCAGGCTTGATAGAAACAGGTTCCTATGTTTAGGGCAGATCCCTAGCCTCTC
GCTCACAGTGAGTCTGCATGTCCTAGATTCTGGTTATTGCTGGAGCATCCATTAAAGTCTACCAAACTCAGGACAGAAGAAGATAGCAGT
GGATTTGTAAAAATTTTTAGTTTATAAATTACAGTCATTGGGGAAACACTAGTAAGGTCATGTGATCTTTTGGACCAGGATTTTCTCTCT
GTCTTCTCTCTGGGTGTGTGTGTGTGTATGTACAGAAGGGCTACCAGGAAGTGTCAACCATGTTAGATTTTCTGTAGTCTTCCAGAAACA
GTGCAGCCCATACAACAGGAATCTTAATTTTCCTCACAGCAAATATAACAGGATGGAACAGTTAGTGTTTTGTTTTCACAAGTGTCCACC
ACTCCATCTGCCCTGCATGGAGAGGGCTCTCTCACTGCTAGATCTAGGCTGAGCCATCTGGAAGGATCAAAGGGTGTGGGAGTATCACCC
CCTCTCAGGCTGCAGAAGGTCTCGAGGGTGGCGTCACAGCAGGATTTCCGCCTTCTGCATTGCACTGCACAGCCCCATGGAACATGAGGC
ACTTGAGGCCTTGCTTCTTGGAGCCTCTGGGGAGCAGAGTAGGTCACTGCCCTCTGGGAGTGTTTTGCAGTAGTTTTGTAAATGTGTTGC
TACATAGTCAAGTTCCTTTGTGGCAAAGAAATATTTTGTTTTGATATTAGGAGCCAGCCCATGTAATGCCTCTCAGGCTTGCTTGCTTAG
AAGAAAAAAGTCACCCTTTGTGGTTTTTAAGAAAAAAATTCTGTGCAGATCTGTTCCTCCTCCTGCTCCTTCCCTTTTCTCTACATACAG
TGCTCATTGGAGGCTCCTGCTAAACCTTCTTAACCAGAGAAATAATAGGTATTTGTTAGACCTGAGTGTACATTTCACATGTTATCCTTC
ACATATTTCTCATTTTCATCTAGTACTTTCTTAATGCCTTTGTTGGAGTCCGCATCCTCATCTTTAAAAAAAAAAAAAAAAAAACAGCTT
AGCCTAAGCCACATTCACTTTTTTTAGTTCACAAAAAGGATTTAATAGCCACAATGTGATTTTTGCCACAACTGTGTGATTTTAATATTC
TCTAATATCAAGGGCGGATTTAGAATTGCAGGAAATACCTGGAGAAATCACAGTGGAATGAATTTTTGCTTTAAGAGAAATGAGAGTTGG
CTGTCTCTGTAATTGATAATACAGCTTCATCCTAGTCCCATCTGCATTTCAGAAAATAACCCTCATCTTTACAAAACACAGGACACTTGT
GGGACAGTTAACTCAAGCAGCTATGGGGAGGGAGGAGATTATTGAATGGTGATTAAATAATGCAAATGGCTCTTCTGTTTCTTAAAGACT
GTGGAAGAGGTCAGACTGCCCAGTTGAGGTGGGCAGTTCATACTGCTCAGTTGAGGTGGCAGTCATTTATTCTGAGTCCTGTTGGATAGA
GCCTATCTCCTCAAGGCTACAGAGGCTTCCAGGATATGGAGCTGTGCATGTTAATGGCTCAGCCTTGCCTCCATCAGGGCACCTGCCTAA
CTTGGAGCAAGTGGGAGAGCACCCTAGAGTCATCCTCTGTGCTGTTTCGTGAGTTTTGCAGCGGAGACTTCACCATCCGGAGGAGCTGTG
TTTCTGTGTCACTTGGGATATCACCTAAAAATGAAACATTTGATATTTTAAGGTATAAAAAAAAAGTAAATTGGGGAACATTGGCTGCAG
TCCCTAAAAGATACTGTTGTCTGTGCATCAGGTTAGCTTGAGGTCACCACAGGTCCTGGGAGCCCAGAGAGTTTAGGCATACTCTCCTTT
GGAGGCCAGCAGCCTTTCACAAACCCTGCCTCTAAAAGGGCGGTTTCACATTTGACCATGTTTTTGCATTAGCCTCAGAAACTCTTGTCT
TTAGCTGATAACCTTTGAGGGATGTGAGAAGCCTAGTTGGAGCATCTGAGAAAATGATACCTCTCACCTTCAAATTAATCAAATAGTTTG
TCCTTCTAGTCCCCTTATAAATTAATAAATGGAGGGCTGGTCATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGG
TGGATCACAAGGTCAGGAGTTCAAGACCAGCCTGACCAATATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGTGTAGT
GGCACGCTCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGGATGTTGCAGTGAGCCGAGATCC
CGCCACTGCACTGCAGCCTAGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAGAAAAGGGAAGGGAATCCCATTTTGT
GATGATTTGGGCACACTACTTGAGCTGAGGCTAGCAGTCACATGATTTTGGCTGTCTCTGACCTGAAGCTTTTGAAGTAAGGTTATGTCT
CTTCCCTGAAGCTTTGTTTATAGTGGTAATTTGGTGAGTTTGAGCTTTGAGCTTGTCTTAGAAAATAAGACTGTCCACCTGGGGAGGGGA
GCTTATAGGGAACCCGTGTTAACTCAGAATGCTGAAGAAAGTGCTTTTAGCCAACAAAAGTAAGATTACTATCTAGAAGGTGGAAAGAAG
TCATTGCTTCTGTTCCTCCAGCAGTCAGTTGACTCTAGGTTTCCTTTGGTTTATATCCCCAGTTCTTAATACTAAAACTTATTTGACTTC
CTATCAGGAAGCACACAAAAAAAGCGTCATTTAAAACCCTGGATATAGGCTTTAAAGGATACAAAAACAGCAGCATTGTCGTTTTGCCAG
GTTCATCACCATTTTGATGTGCTACCCATCCTTCCACCCTCCCTTTCCTGCCCCCAAGCCTCCCAGCCAGGCCAGATGTGAAGATTCTAT
TAATCACTGTTTCAGAGAACATTAATTCTTGTATAGAATAATTATCTACTAAATTGCTTATTATCTGTGACTACCTTGCAGAGAACATCT
CAACAGTGCAGTAAAATAGCTCTCCTAGACTTGAGCTTCCAGCCAGGCATTTAGATCACTCTTAAGCCTTTGTGGAATTCTGAGGAAAAA
AAGCAAGATGCCTCAATGCCAATGCTGGGCCATAAGATTCTACTCCCCTCCCTGTAGGGTGGGGCGCGTGGCTCAGCTTTGGAAAATCAT
TTTGCCAGTAATATTGCCTGTGAATCCCTTTAAGAAGTCGTCCTGATCTGAGCCTGTCTTTCTGAGCACTTTGGTGCTGAATTGAAAATG
GTAAGCTAAAGCAGTGACAGATCCACGTAGCCTCTTTAACCTCTTTATTATCTTGCCAAAAAAAAAGTTTCTCAGGTTAAACCTTTGTCT
TTAACCTCCCTTTGTTGTGGAGAAAATGTGTCACTAATCAGTGGTCCAAGGGATATCTAGCTTTGGTTACTCAGTTCCTGCAGCATAACA
GATATGACTTATGCCAGGGAAGGTAGAGGCTGATTATGGAGACACCCAGGAACAGGAATAAGAAGGGATAGGTCTGCTCCACGTAGAACC
TCCCCAGATCGGAAGTTAAGTCTTGGAGAGTTTCCAAAGTGCTGAAGTAAAAAGGAGACTTGGAGGGCCTTTGCTTAATGAGCAAGAGGC
TTGTGTCCTCCCAAGAACATGAGGGAGTTCAGAAGGGAGCTATAGCTCACAGACAGAAACCTGCCCGCTCACCCCATCCCTCGTGACTGG
GAGCATGTTTGCTCAGAATTTTCTAAGAGGACTCTCCCTTCAAAAATCCAATTTGCTCCCAGAATGTTGTTTAGCCTCTGAGAATCTCAC
TCTTTCATTTCCATCTGTGAATGGACATAGATGTGTTGCTCAGGGATCAGAAACATCAGAGTCCAGGGCCCAGTGGCATGGTGTTGCATT
AGTAGTTAGAAAAGTAATTGGTCAGCTCTACTGTAAAAGAAATAAGTATGTAGTACAGTTTTGTAAATGTCAGGTCTGTTCTATTGTTTT
GTGATCTGAAGACTGTCAAACTGGTTGATAATCAAAGAAAAGGTTGGTGGTTAGAATAAGTAAAATTTCAGTTAGAAAGATATAGCTTAC
CAGTTTTCCATGTGCTTAAGGAAGTCAAGAATATTTCAGGTTGTTGAGAACTGTTGTAAAATGGAATTGAAGCTAGTGTCTCTCACCTTC
TTAGGTGTATCAGAGAGAGGAAGTGGAAGGCCAGTAGTAGCATCTTCATACTTACTTTTGCCAGCCCAGCCTCCATTTCAAAGACTTTGT
CTTCCATCCTATCCAATGACATGGTCAGGGATGGGCTCTGAGGAGGCAGTGAGGCCCCACCTTGGTTTGCTCCACTGTGGTGTGTAGTCT
CCAAACAGCTTAAGGGTTTTTAAGTTTTCTCACGATTACCTCCACTCCACTCATCTACTATCAGCATCAGAAAGGTTAACATCCCTGGGA
CCATTCTACTTATAAAAGAGATGAACTAGTGTGCTTTCTCCCCTTTTCCAGGTGTGCCATCCATATACAATCTCCTCTTGGCCAAGTTCA
ACAAATGTTTCCAGGGAACCCCGTGGGTTGAGGCAAAGTAGCCAAGATGTATTGAGTTAAGTTTTTCTAGAGGACAAAAGTATTTCTTGT
CCCTTTTCCCTCATGCTCATATGTTTTAGCTGAGGCGTAAATGGCCAAGTTGAGTAATATCTGTGGAACTGAGACAGAGAGCCAGGGACC
CATGTACCCAGGGACCAGTCCCCTGGGGAATCACACAGTGGCTCAGACTAGACTGCTCTATCCCACCAGAACTCTGCTGCTGTTCATTTC
CATCAGGACCACCCAGGAAAGCAAATAAGTTAGCCTTCTCATCATTAGGTCACCTAATCTCTTGGGTTGCAGGATGAGAGCATATATAGA
TCTCCTGTTTAGAGAGTGTGTTCATAATTGTAGAAAGGGATAGAAAATGGAATAACCAAGAGGCTGTGTCATTTTTTAAGAGGATGGCAA
GGATGACCTCAAATGAGCTCAACAAAACTGGGAATCCAAGGAATGGTGCTTGTAGGGAAAGAGAGGTCAGTTGTGGTCCTTAAACCTCTT
GGCACCTTGTGCGGGTTATAAAACAAGGAGCTGGAGTAAAATTGCCCTTACCCCCAATCCAAATGCTGTCCAGGATTTAGGAGCTACCCA
ACCTGTGGTTATATGGTGTTGGTTTCCATTTTTTGTTTGTTTGCTTGTTTCCAAAATAGCCTTGCTTGGTACTGCATGGAAAGTTCAAGC
TTTTCTTCTTGCCCGCTCAGGGCTGGCCTCTTCCCCGTGTCTTCACAGCGTCCCTAAGGAAGATTTTTGCAGCACTCTCTGGAGCTGAGG
GGAGTGAAATTTGGTCCAGAGAAGGCGGAAGGAAATAGTTTTCCTGTTTCCTTTTCTCGAGGTGGATGTCCTCAGGCTTCCTTCACACCT
CCTTCTCATGGGTGCGGCTGGCAGTACAGTCAGGCTGTGGAGGAGGGCTGAGAAGAAAGGGGCACTGGTCCAGCCCCAGGTTTGGTCTGA
GACAGGTACACAGCAGATACCATCCCACCTTCCTCTCTAAAGAACAGGCCAGCCACACATATAACCCTTTCCCTACTTTACTAATGTATC
CCTTATGTGGTACCAGCAATGGAGGACAGGCAGACTTACCCCCTGCCATCTAGAGAGAATGTTGTTATTACCCGTAAAACTTGACCACCC
CCATATCCCACTCCTTTTTGTAAAAACAAATGCTTAAACCTGTGAGCCTGCCGTTCCTTTCTATGTGTTAATCAGTTTCCTTCCATTTGA

>17112_17112_1_CLIC1-NUDT3_CLIC1_chr6_31701343_ENST00000375780_NUDT3_chr6_34263462_ENST00000607016_length(amino acids)=149AA_BP=
MANMSSPAVLDSGFRAASLGYLGGHSTASRNSSILLVSVCTSVPYSRNGSCPPGHSFCTVSVRLLVSTVVTLKVTPLSHSTMNSLWENGQ

--------------------------------------------------------------
>17112_17112_2_CLIC1-NUDT3_CLIC1_chr6_31701343_ENST00000395892_NUDT3_chr6_34263462_ENST00000607016_length(transcript)=9975nt_BP=592nt
GGATTTGATTGGCGCAGTGGGAAGCCCGCGAGAAGAGGTGGAAGCATTCGAATTACATCAAATTCTGGCAGAGAGAAGTAGTTCTGATCA
GAACACTCACACCCCTACTGGGACATGCCCATACCCCTTCGCACTTCTACACACCCCTGAAGACAGAGAGCCCCTCCCAGTTCCCCCAGG
GACGGCCACTTCCTGGTCCCCGACGCAACCATGGCTGAAGAACAACCGCAGGTCGAATTGTTCGTGAAGGCTGGCAGTGATGGGGCCAAG
ATTGGGAACTGCCCATTCTCCCAGAGACTGTTCATGGTACTGTGGCTCAAGGGAGTCACCTTCAATGTTACCACCGTTGACACCAAAAGG
CGGACCGAGACAGTGCAGAAGCTGTGCCCAGGGGGGCAGCTCCCATTCCTGCTGTATGGCACTGAAGTGCACACAGACACCAACAAGATT
GAGGAATTTCTGGAGGCAGTGCTGTGCCCTCCCAGGTACCCCAAGCTGGCAGCTCTGAACCCTGAGTCCAACACAGCTGGGCTGGACATA
TTTGCCAAATTTTCTGCCTACATCAAGAATTCAAACCCAGCACTCAATGACAGCTGGAGTAAAAGGGACATTGGGAAGATTAGTTGGAAT
TTTTGAGAACCAGGAGAGGAAGCACAGGACGTATGTCTATGTGCTCATTGTCACTGAAGTGCTGGAAGACTGGGAAGATTCAGTTAACAT
TGGAAGGAAGAGGGAATGGTTTAAAATAGAAGACGCCATAAAAGTGCTGCAGTATCACAAACCCGTGCAGGCATCATATTTTGAAACATT
GAGGCAAGGCTACTCAGCCAACAATGGCACCCCAGTCGTGGCCACCACATACTCGGTTTCTGCTCAGAGCTCGATGTCAGGCATCAGATG
ACTGAAGACTTCCTGTAAGAGAAATGGAAATTGGAAACTAGACTGAAGTGCAAATCTTCCCTCTCACCCTGGCTCTTTCCACTTCTCACA
GGCCTCCTCTTTCAAATAAGGCATGGTGGGCAGCAAAGAAAGGGTGTATTGATAATGTTGCTGTTTGGTGTTAAGTGATGGGGCTTTTTC
TTCTGTTTTTATTGAGGGTGGGGGTTGGGTGTGTAATTTGTAAGTACTTTTGTGCATGATCTGTCCCTCCCTCTTCCCACCCCTGCAGTC
CTCTGAAGAGAGGCCAACAGCCTTCCCCTGCCTTGGATTCTGAAGTGTTCCTGTTTGTCTTATCCTGGCCCTGGCCAGACGTTTTCTTTG
ATTTTTAATTTTTTTTTTTTATTAAAAGATACCAGTATGAGATGAAAACTTCCAATAATTTGTCCTATAATGTGCTGTACAGTTCAGTAG
AGTGGTCACTTTCACTGCAGTATACATTTATCTACACATTATATATCGGACATATAATATGTAAATAAATGACTTCTAGAAAGAGAAATT
TGTTTAATTTTTCAAGGTTTTTTTCTCTTTTAATTTGGGCATTTCTAGAATTGAGAGCCTCACAATTAACATACCTTTTTGTTTTCGATG
CTAGTGGCTGGGCAGGTTGCCCTGTCCTTTCTCTATTTCCCAGTCATTGACTGTAGATATGGGAAGAGTTTAGCTACCTTCATAGTGCTC
CCAGGACTCATGGCCTTTCCTTCTTTAAGCTGTATTTCCCTGCCCAGAAAGAAACAGGAAGAAACCTTTTTTTATTTTTTTATTTTTTTT
TAACCAAGCAAGGAGCAAATGGCCTCAGCCCAGATCTGTAAAAACAATGATAGAAATTGAATTCTGCCCCACATGTTGACAGTAGAGTTG
GAACTGGATTCTTGGGATTACTTATCTAAAAAACTGGAGCATCAGGTCCATTTCTGTTCTGCTGGTTTGGAATCTTTTCCGTAATGCTAT
TTATTGCCAACAATGGCCTCTCTTTGTGTCCATATATGCCTTACACCGTGCTGACCTGGGTATCATCCATGTGCTCTGAAGCATCCAACT
TTACTTTGCAGGTGCATCAATGTAGTCCTGTCCCTGAACTGAGTAACCGTGTTCCTGAAAAGTACACTAGGGAAATTCACCTGCTTGCTT
GTCTTTGTATTGGCATGGCACTTGTGATTGCACCATGGAGCATGCTCAGAGCTATTAAATTGGTCTCCCATCTCCCACCAGGATATGAAA
GGTCCATATGGGAGGCCACGTAATCACTTATTACAGTGGTTACATAATACACTGGCTCACTGCAGACTCTCTTGTTTTTTGATACAGTTT
CGTGCTGGCTTCATTTGCCAATTGTGTTGTTTAGTTCGGAAGTAAGAGGGTCTTGAGATTGAGGGGTAGGGAGGGCTACACTGACTGATC
CGTGGCTTAAGACAGGAGATTATCTCTGTACTCCAGTGGCATCTCCTTAGCCAAGATGTGAAATTAAAATCATAGTTCGCCTCATTTAAA
AATTCTAATAAAGCACTCAAACTTTGAAAAGCTTTTACTTTTCCCTCCTACTAAAAGAAATGTATGTACCTCATAGCCCTGTGTCATTTA
GTGTTCAGCACTTTTGGGAACATCAGTTGGTGAACTTTAAATTTTGCTGTCTACTCACTGGGCACGGTGGCTCACACCTGTAATCCCAGC
ACTTTGGGAGGCTGAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGACCAACATGGTGAAACCCCGTCTCTACTAAAAA
TGCAGAAATTAGGTGGGCGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCGAGATAATCGCTTGAACCTGGGAGGCAGAGGTTGCAGTG
AGCCGAGATTGCACCACTGTCGTCCAGCCTGGGTGATAAGAGTGAAACTCCATCTCAAAAAAAAAAAAAAAAAATTTTTTTTTTTTTTTT
TGCTATATACTCTTAGTTTACATCCTCTCCCCCAATCTTCACACACAGAGCCAAAGAGCAGTTATATTCTTGGGATACCATGATACCTCT
GGGAAAGGAATTATATTCCCAAGGAGAGGTCCCATTGGATAAGAACAATACCATGGGACTTGAGTCTGAATGCCAACTTACTATTCACAC
ATCCTTCTTAAAAACGAACACACTGTTTCTTTTCCTGACCTAGAGCATTCTAAAGTTCTGTTCAAATAAATAAAGGGCAAAATAAAGTAG
ATTTAACCAAGTGCCAGGTGGAATTCAAAAAACACATTCTTCCAGATAAATTCTACCTTTATGGTATGGATTTGAAAGTACTTTGCAGGA
AAACAGTCAGTACTCTTTAAAAAGGGACTGCAGGGCTGGGTGTAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGT
GGGTCACTTGAGGCCAGGAGTTTGAGACCAGCCTGACCAACATGGCAAAACCCCATCTCTACTAAAATACAAAAATTAGCTGGGCATGAT
GGTGCACTCCTGTAATCCCAGCTACTTGGTAGGCTGAAGCATGAGAATTGCTTAAACCTGGGAGGCAGAGGTTGCAGTAAGCCAAGATCA
TGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTTAATAAATAAATAAGAAAATAAAACGGAACTGCAGTGCTAACAGTAA
TTTATACATTTTTAAATGTTCTGAGTATGTTTTGACTGGGCTAGTGTAACAATATACTACCCTGAAAGTGCAGTTTTGATTGTTGTTGGT
GTCTTTGGGTCAGGAAAGTGAACTGTGCCAAGAAGTATTTTTCAGTGACATGAATGGATTCCTGTTAATGCAATTGACTGAGAGATTGTG
CTTACGCTTTCTTAACTGACAAAAAGAGGCTTTGTCCAACATCAGAATTGTTGAAACTGGTGCTGTTTTCTGTTGCACTGGGATTCTGAT
GATCTGGGATTTTCCCTCCTTGGCACAGTAAACACCATGACTGTCTTTATTGAGAATGTCGTCACAGTCCTTTAGTGATAGATTAGTTAG
ACCCATGGTTGCAATACCTTTATCTCCCCAAAGAAAATAATCAAAAGAAAGCACAAAAGCTACCCTGTTTGCAGAATATTTCACTGACAT
TGATTTGTCATTAATTCTACCAGAGCTGACCTCATTCAGGCTTGATAGAAACAGGTTCCTATGTTTAGGGCAGATCCCTAGCCTCTCGCT
CACAGTGAGTCTGCATGTCCTAGATTCTGGTTATTGCTGGAGCATCCATTAAAGTCTACCAAACTCAGGACAGAAGAAGATAGCAGTGGA
TTTGTAAAAATTTTTAGTTTATAAATTACAGTCATTGGGGAAACACTAGTAAGGTCATGTGATCTTTTGGACCAGGATTTTCTCTCTGTC
TTCTCTCTGGGTGTGTGTGTGTGTATGTACAGAAGGGCTACCAGGAAGTGTCAACCATGTTAGATTTTCTGTAGTCTTCCAGAAACAGTG
CAGCCCATACAACAGGAATCTTAATTTTCCTCACAGCAAATATAACAGGATGGAACAGTTAGTGTTTTGTTTTCACAAGTGTCCACCACT
CCATCTGCCCTGCATGGAGAGGGCTCTCTCACTGCTAGATCTAGGCTGAGCCATCTGGAAGGATCAAAGGGTGTGGGAGTATCACCCCCT
CTCAGGCTGCAGAAGGTCTCGAGGGTGGCGTCACAGCAGGATTTCCGCCTTCTGCATTGCACTGCACAGCCCCATGGAACATGAGGCACT
TGAGGCCTTGCTTCTTGGAGCCTCTGGGGAGCAGAGTAGGTCACTGCCCTCTGGGAGTGTTTTGCAGTAGTTTTGTAAATGTGTTGCTAC
ATAGTCAAGTTCCTTTGTGGCAAAGAAATATTTTGTTTTGATATTAGGAGCCAGCCCATGTAATGCCTCTCAGGCTTGCTTGCTTAGAAG
AAAAAAGTCACCCTTTGTGGTTTTTAAGAAAAAAATTCTGTGCAGATCTGTTCCTCCTCCTGCTCCTTCCCTTTTCTCTACATACAGTGC
TCATTGGAGGCTCCTGCTAAACCTTCTTAACCAGAGAAATAATAGGTATTTGTTAGACCTGAGTGTACATTTCACATGTTATCCTTCACA
TATTTCTCATTTTCATCTAGTACTTTCTTAATGCCTTTGTTGGAGTCCGCATCCTCATCTTTAAAAAAAAAAAAAAAAAAACAGCTTAGC
CTAAGCCACATTCACTTTTTTTAGTTCACAAAAAGGATTTAATAGCCACAATGTGATTTTTGCCACAACTGTGTGATTTTAATATTCTCT
AATATCAAGGGCGGATTTAGAATTGCAGGAAATACCTGGAGAAATCACAGTGGAATGAATTTTTGCTTTAAGAGAAATGAGAGTTGGCTG
TCTCTGTAATTGATAATACAGCTTCATCCTAGTCCCATCTGCATTTCAGAAAATAACCCTCATCTTTACAAAACACAGGACACTTGTGGG
ACAGTTAACTCAAGCAGCTATGGGGAGGGAGGAGATTATTGAATGGTGATTAAATAATGCAAATGGCTCTTCTGTTTCTTAAAGACTGTG
GAAGAGGTCAGACTGCCCAGTTGAGGTGGGCAGTTCATACTGCTCAGTTGAGGTGGCAGTCATTTATTCTGAGTCCTGTTGGATAGAGCC
TATCTCCTCAAGGCTACAGAGGCTTCCAGGATATGGAGCTGTGCATGTTAATGGCTCAGCCTTGCCTCCATCAGGGCACCTGCCTAACTT
GGAGCAAGTGGGAGAGCACCCTAGAGTCATCCTCTGTGCTGTTTCGTGAGTTTTGCAGCGGAGACTTCACCATCCGGAGGAGCTGTGTTT
CTGTGTCACTTGGGATATCACCTAAAAATGAAACATTTGATATTTTAAGGTATAAAAAAAAAGTAAATTGGGGAACATTGGCTGCAGTCC
CTAAAAGATACTGTTGTCTGTGCATCAGGTTAGCTTGAGGTCACCACAGGTCCTGGGAGCCCAGAGAGTTTAGGCATACTCTCCTTTGGA
GGCCAGCAGCCTTTCACAAACCCTGCCTCTAAAAGGGCGGTTTCACATTTGACCATGTTTTTGCATTAGCCTCAGAAACTCTTGTCTTTA
GCTGATAACCTTTGAGGGATGTGAGAAGCCTAGTTGGAGCATCTGAGAAAATGATACCTCTCACCTTCAAATTAATCAAATAGTTTGTCC
TTCTAGTCCCCTTATAAATTAATAAATGGAGGGCTGGTCATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGG
ATCACAAGGTCAGGAGTTCAAGACCAGCCTGACCAATATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGTGTAGTGGC
ACGCTCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGGATGTTGCAGTGAGCCGAGATCCCGC
CACTGCACTGCAGCCTAGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAGAAAAGGGAAGGGAATCCCATTTTGTGAT
GATTTGGGCACACTACTTGAGCTGAGGCTAGCAGTCACATGATTTTGGCTGTCTCTGACCTGAAGCTTTTGAAGTAAGGTTATGTCTCTT
CCCTGAAGCTTTGTTTATAGTGGTAATTTGGTGAGTTTGAGCTTTGAGCTTGTCTTAGAAAATAAGACTGTCCACCTGGGGAGGGGAGCT
TATAGGGAACCCGTGTTAACTCAGAATGCTGAAGAAAGTGCTTTTAGCCAACAAAAGTAAGATTACTATCTAGAAGGTGGAAAGAAGTCA
TTGCTTCTGTTCCTCCAGCAGTCAGTTGACTCTAGGTTTCCTTTGGTTTATATCCCCAGTTCTTAATACTAAAACTTATTTGACTTCCTA
TCAGGAAGCACACAAAAAAAGCGTCATTTAAAACCCTGGATATAGGCTTTAAAGGATACAAAAACAGCAGCATTGTCGTTTTGCCAGGTT
CATCACCATTTTGATGTGCTACCCATCCTTCCACCCTCCCTTTCCTGCCCCCAAGCCTCCCAGCCAGGCCAGATGTGAAGATTCTATTAA
TCACTGTTTCAGAGAACATTAATTCTTGTATAGAATAATTATCTACTAAATTGCTTATTATCTGTGACTACCTTGCAGAGAACATCTCAA
CAGTGCAGTAAAATAGCTCTCCTAGACTTGAGCTTCCAGCCAGGCATTTAGATCACTCTTAAGCCTTTGTGGAATTCTGAGGAAAAAAAG
CAAGATGCCTCAATGCCAATGCTGGGCCATAAGATTCTACTCCCCTCCCTGTAGGGTGGGGCGCGTGGCTCAGCTTTGGAAAATCATTTT
GCCAGTAATATTGCCTGTGAATCCCTTTAAGAAGTCGTCCTGATCTGAGCCTGTCTTTCTGAGCACTTTGGTGCTGAATTGAAAATGGTA
AGCTAAAGCAGTGACAGATCCACGTAGCCTCTTTAACCTCTTTATTATCTTGCCAAAAAAAAAGTTTCTCAGGTTAAACCTTTGTCTTTA
ACCTCCCTTTGTTGTGGAGAAAATGTGTCACTAATCAGTGGTCCAAGGGATATCTAGCTTTGGTTACTCAGTTCCTGCAGCATAACAGAT
ATGACTTATGCCAGGGAAGGTAGAGGCTGATTATGGAGACACCCAGGAACAGGAATAAGAAGGGATAGGTCTGCTCCACGTAGAACCTCC
CCAGATCGGAAGTTAAGTCTTGGAGAGTTTCCAAAGTGCTGAAGTAAAAAGGAGACTTGGAGGGCCTTTGCTTAATGAGCAAGAGGCTTG
TGTCCTCCCAAGAACATGAGGGAGTTCAGAAGGGAGCTATAGCTCACAGACAGAAACCTGCCCGCTCACCCCATCCCTCGTGACTGGGAG
CATGTTTGCTCAGAATTTTCTAAGAGGACTCTCCCTTCAAAAATCCAATTTGCTCCCAGAATGTTGTTTAGCCTCTGAGAATCTCACTCT
TTCATTTCCATCTGTGAATGGACATAGATGTGTTGCTCAGGGATCAGAAACATCAGAGTCCAGGGCCCAGTGGCATGGTGTTGCATTAGT
AGTTAGAAAAGTAATTGGTCAGCTCTACTGTAAAAGAAATAAGTATGTAGTACAGTTTTGTAAATGTCAGGTCTGTTCTATTGTTTTGTG
ATCTGAAGACTGTCAAACTGGTTGATAATCAAAGAAAAGGTTGGTGGTTAGAATAAGTAAAATTTCAGTTAGAAAGATATAGCTTACCAG
TTTTCCATGTGCTTAAGGAAGTCAAGAATATTTCAGGTTGTTGAGAACTGTTGTAAAATGGAATTGAAGCTAGTGTCTCTCACCTTCTTA
GGTGTATCAGAGAGAGGAAGTGGAAGGCCAGTAGTAGCATCTTCATACTTACTTTTGCCAGCCCAGCCTCCATTTCAAAGACTTTGTCTT
CCATCCTATCCAATGACATGGTCAGGGATGGGCTCTGAGGAGGCAGTGAGGCCCCACCTTGGTTTGCTCCACTGTGGTGTGTAGTCTCCA
AACAGCTTAAGGGTTTTTAAGTTTTCTCACGATTACCTCCACTCCACTCATCTACTATCAGCATCAGAAAGGTTAACATCCCTGGGACCA
TTCTACTTATAAAAGAGATGAACTAGTGTGCTTTCTCCCCTTTTCCAGGTGTGCCATCCATATACAATCTCCTCTTGGCCAAGTTCAACA
AATGTTTCCAGGGAACCCCGTGGGTTGAGGCAAAGTAGCCAAGATGTATTGAGTTAAGTTTTTCTAGAGGACAAAAGTATTTCTTGTCCC
TTTTCCCTCATGCTCATATGTTTTAGCTGAGGCGTAAATGGCCAAGTTGAGTAATATCTGTGGAACTGAGACAGAGAGCCAGGGACCCAT
GTACCCAGGGACCAGTCCCCTGGGGAATCACACAGTGGCTCAGACTAGACTGCTCTATCCCACCAGAACTCTGCTGCTGTTCATTTCCAT
CAGGACCACCCAGGAAAGCAAATAAGTTAGCCTTCTCATCATTAGGTCACCTAATCTCTTGGGTTGCAGGATGAGAGCATATATAGATCT
CCTGTTTAGAGAGTGTGTTCATAATTGTAGAAAGGGATAGAAAATGGAATAACCAAGAGGCTGTGTCATTTTTTAAGAGGATGGCAAGGA
TGACCTCAAATGAGCTCAACAAAACTGGGAATCCAAGGAATGGTGCTTGTAGGGAAAGAGAGGTCAGTTGTGGTCCTTAAACCTCTTGGC
ACCTTGTGCGGGTTATAAAACAAGGAGCTGGAGTAAAATTGCCCTTACCCCCAATCCAAATGCTGTCCAGGATTTAGGAGCTACCCAACC
TGTGGTTATATGGTGTTGGTTTCCATTTTTTGTTTGTTTGCTTGTTTCCAAAATAGCCTTGCTTGGTACTGCATGGAAAGTTCAAGCTTT
TCTTCTTGCCCGCTCAGGGCTGGCCTCTTCCCCGTGTCTTCACAGCGTCCCTAAGGAAGATTTTTGCAGCACTCTCTGGAGCTGAGGGGA
GTGAAATTTGGTCCAGAGAAGGCGGAAGGAAATAGTTTTCCTGTTTCCTTTTCTCGAGGTGGATGTCCTCAGGCTTCCTTCACACCTCCT
TCTCATGGGTGCGGCTGGCAGTACAGTCAGGCTGTGGAGGAGGGCTGAGAAGAAAGGGGCACTGGTCCAGCCCCAGGTTTGGTCTGAGAC
AGGTACACAGCAGATACCATCCCACCTTCCTCTCTAAAGAACAGGCCAGCCACACATATAACCCTTTCCCTACTTTACTAATGTATCCCT
TATGTGGTACCAGCAATGGAGGACAGGCAGACTTACCCCCTGCCATCTAGAGAGAATGTTGTTATTACCCGTAAAACTTGACCACCCCCA
TATCCCACTCCTTTTTGTAAAAACAAATGCTTAAACCTGTGAGCCTGCCGTTCCTTTCTATGTGTTAATCAGTTTCCTTCCATTTGAGCT

>17112_17112_2_CLIC1-NUDT3_CLIC1_chr6_31701343_ENST00000395892_NUDT3_chr6_34263462_ENST00000607016_length(amino acids)=147AA_BP=
MVPDATMAEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFL

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Fusion Gene PPI Analysis for CLIC1-NUDT3

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for CLIC1-NUDT3

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for CLIC1-NUDT3

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	CLIC1	C0006142	Malignant neoplasm of breast	1	CTD_human
Hgene	CLIC1	C0019693	HIV Infections	1	CTD_human
Hgene	CLIC1	C0022548	Keloid	1	CTD_human
Hgene	CLIC1	C0023893	Liver Cirrhosis, Experimental	1	CTD_human
Hgene	CLIC1	C0027627	Neoplasm Metastasis	1	CTD_human
Hgene	CLIC1	C0029408	Degenerative polyarthritis	1	CTD_human
Hgene	CLIC1	C0086743	Osteoarthrosis Deformans	1	CTD_human
Hgene	CLIC1	C0279626	Squamous cell carcinoma of esophagus	1	CTD_human
Hgene	CLIC1	C0678222	Breast Carcinoma	1	CTD_human
Hgene	CLIC1	C1257931	Mammary Neoplasms, Human	1	CTD_human
Hgene	CLIC1	C1458155	Mammary Neoplasms	1	CTD_human
Hgene	CLIC1	C4505456	HIV Coinfection	1	CTD_human
Hgene	CLIC1	C4704874	Mammary Carcinoma, Human	1	CTD_human

Fusion Gene Studies in Kim Lab

Fusion gene:CLIC1-NUDT3 (FusionGDB2 ID:HG1192TG11165)

Fusion Gene Summary for CLIC1-NUDT3

Fusion Gene ORF analysis for CLIC1-NUDT3

Fusion Genomic Features for CLIC1-NUDT3

Fusion Protein Features for CLIC1-NUDT3

Fusion Gene Sequence for CLIC1-NUDT3

Fusion Gene PPI Analysis for CLIC1-NUDT3

Related Drugs for CLIC1-NUDT3

Related Diseases for CLIC1-NUDT3

Fusion Gene Studies
in Kim Lab