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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
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Fusion gene:AASDH-LRRC66 (FusionGDB2 ID:HG132949TG339977)

Fusion Gene Summary for AASDH-LRRC66

Fusion gene summary

Fusion gene information	Fusion gene name: AASDH-LRRC66
	Fusion gene ID: hg132949tg339977
		Hgene	Tgene
	Gene symbol	AASDH	LRRC66
	Gene ID	132949	339977
	Gene name	aminoadipate-semialdehyde dehydrogenase	leucine rich repeat containing 66
	Synonyms	ACSF4\|LYS2\|NRPS1098\|NRPS998	-
	Cytomap	('AASDH')('LRRC66') 4q12	4q12
	Type of gene	protein-coding	protein-coding
	Description	beta-alanine-activating enzyme2-aminoadipic 6-semialdehyde dehydrogenaseacyl-CoA synthetase family member 4non-ribosomal peptide synthetase 1098non-ribosomal peptide synthetase 998	leucine-rich repeat-containing protein 66
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000205214, ENST00000434343, ENST00000451613, ENST00000502617, ENST00000513376, ENST00000602986, ENST00000510762,
Fusion gene scores	* DoF score	6 X 7 X 4=168	2 X 2 X 2=8
	# samples	7	3
	** MAII score	log2(7/168*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(3/8*10)=1.90689059560852
Context	PubMed: AASDH [Title/Abstract] AND LRRC66 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	AASDH(57217508)-LRRC66(52869558), # samples:3
Anticipated loss of major functional domain due to fusion event.	AASDH-LRRC66 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. AASDH-LRRC66 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across AASDH (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across LRRC66 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	GBM	TCGA-06-2559-01A	AASDH	chr4	57217508	-	LRRC66	chr4	52864103	-
ChimerDB4	GBM	TCGA-06-2559-01A	AASDH	chr4	57217508	-	LRRC66	chr4	52869558	-
ChimerDB4	GBM	TCGA-06-2559	AASDH	chr4	57217507	-	LRRC66	chr4	52864103	-

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Fusion Gene ORF analysis for AASDH-LRRC66

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
Frame-shift	ENST00000205214	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52864103	-
Frame-shift	ENST00000205214	ENST00000343457	AASDH	chr4	57217507	-	LRRC66	chr4	52864103	-
Frame-shift	ENST00000434343	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52869558	-
Frame-shift	ENST00000451613	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52864103	-
Frame-shift	ENST00000451613	ENST00000343457	AASDH	chr4	57217507	-	LRRC66	chr4	52864103	-
Frame-shift	ENST00000502617	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52864103	-
Frame-shift	ENST00000502617	ENST00000343457	AASDH	chr4	57217507	-	LRRC66	chr4	52864103	-
Frame-shift	ENST00000513376	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52869558	-
Frame-shift	ENST00000602986	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52869558	-
In-frame	ENST00000205214	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52869558	-
In-frame	ENST00000434343	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52864103	-
In-frame	ENST00000434343	ENST00000343457	AASDH	chr4	57217507	-	LRRC66	chr4	52864103	-
In-frame	ENST00000451613	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52869558	-
In-frame	ENST00000502617	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52869558	-
In-frame	ENST00000513376	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52864103	-
In-frame	ENST00000513376	ENST00000343457	AASDH	chr4	57217507	-	LRRC66	chr4	52864103	-
In-frame	ENST00000602986	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52864103	-
In-frame	ENST00000602986	ENST00000343457	AASDH	chr4	57217507	-	LRRC66	chr4	52864103	-
intron-3CDS	ENST00000510762	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52864103	-
intron-3CDS	ENST00000510762	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52869558	-
intron-3CDS	ENST00000510762	ENST00000343457	AASDH	chr4	57217507	-	LRRC66	chr4	52864103	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000205214	AASDH	chr4	57217508	-	ENST00000343457	LRRC66	chr4	52869558	-	4697	1873	1845	4019	724
ENST00000451613	AASDH	chr4	57217508	-	ENST00000343457	LRRC66	chr4	52869558	-	4686	1862	1834	4008	724
ENST00000502617	AASDH	chr4	57217508	-	ENST00000343457	LRRC66	chr4	52869558	-	4697	1873	1845	4019	724
ENST00000513376	AASDH	chr4	57217507	-	ENST00000343457	LRRC66	chr4	52864103	-	4178	1524	132	3500	1122
ENST00000434343	AASDH	chr4	57217507	-	ENST00000343457	LRRC66	chr4	52864103	-	3899	1245	1008	3221	737
ENST00000602986	AASDH	chr4	57217507	-	ENST00000343457	LRRC66	chr4	52864103	-	4367	1713	333	3689	1118
ENST00000513376	AASDH	chr4	57217508	-	ENST00000343457	LRRC66	chr4	52864103	-	4178	1524	132	3500	1122
ENST00000434343	AASDH	chr4	57217508	-	ENST00000343457	LRRC66	chr4	52864103	-	3899	1245	1008	3221	737
ENST00000602986	AASDH	chr4	57217508	-	ENST00000343457	LRRC66	chr4	52864103	-	4367	1713	333	3689	1118

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000205214	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52869558	-	0.00084169	0.99915826
ENST00000451613	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52869558	-	0.000853566	0.99914646
ENST00000502617	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52869558	-	0.00084169	0.99915826
ENST00000513376	ENST00000343457	AASDH	chr4	57217507	-	LRRC66	chr4	52864103	-	0.000274797	0.99972516
ENST00000434343	ENST00000343457	AASDH	chr4	57217507	-	LRRC66	chr4	52864103	-	0.001506755	0.9984932
ENST00000602986	ENST00000343457	AASDH	chr4	57217507	-	LRRC66	chr4	52864103	-	0.000403471	0.99959654
ENST00000513376	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52864103	-	0.000274797	0.99972516
ENST00000434343	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52864103	-	0.001506755	0.9984932
ENST00000602986	ENST00000343457	AASDH	chr4	57217508	-	LRRC66	chr4	52864103	-	0.000403471	0.99959654

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Fusion Genomic Features for AASDH-LRRC66

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

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Fusion Protein Features for AASDH-LRRC66

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:57217508/chr4:52869558)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

AASDH

chr4:57217507

chr4:52864103

ENST00000205214

198_206

564

1099.0

Nucleotide binding

ATP

Hgene

AASDH

chr4:57217507

chr4:52864103

ENST00000451613

198_206

564

858.0

Nucleotide binding

ATP

Hgene

AASDH

chr4:57217507

chr4:52864103

ENST00000502617

198_206

564

842.0

Nucleotide binding

ATP

Hgene

AASDH

chr4:57217507

chr4:52864103

ENST00000513376

198_206

464

999.0

Nucleotide binding

ATP

Hgene

AASDH

chr4:57217508

chr4:52864103

ENST00000205214

198_206

564

1099.0

Nucleotide binding

ATP

Hgene

AASDH

chr4:57217508

chr4:52864103

ENST00000451613

198_206

564

858.0

Nucleotide binding

ATP

Hgene

AASDH

chr4:57217508

chr4:52864103

ENST00000502617

198_206

564

842.0

Nucleotide binding

ATP

Hgene

AASDH

chr4:57217508

chr4:52864103

ENST00000513376

198_206

464

999.0

Nucleotide binding

ATP

Hgene

AASDH

chr4:57217508

chr4:52869558

ENST00000205214

198_206

564

1099.0

Nucleotide binding

ATP

Hgene

AASDH

chr4:57217508

chr4:52869558

ENST00000451613

198_206

564

858.0

Nucleotide binding

ATP

Hgene

AASDH

chr4:57217508

chr4:52869558

ENST00000502617

198_206

564

842.0

Nucleotide binding

ATP

Hgene

AASDH

chr4:57217508

chr4:52869558

ENST00000513376

198_206

464

999.0

Nucleotide binding

ATP

Tgene

LRRC66

chr4:57217507

chr4:52864103

ENST00000343457

220_241

222

881.0

Repeat

Note=LRR 6

Tgene

LRRC66

chr4:57217508

chr4:52864103

ENST00000343457

220_241

222

881.0

Repeat

Note=LRR 6

Tgene

LRRC66

chr4:57217508

chr4:52869558

ENST00000343457

172_193

165

881.0

Repeat

Note=LRR 4

Tgene

LRRC66

chr4:57217508

chr4:52869558

ENST00000343457

196_217

165

881.0

Repeat

Note=LRR 5

Tgene

LRRC66

chr4:57217508

chr4:52869558

ENST00000343457

220_241

165

881.0

Repeat

Note=LRR 6

Tgene

LRRC66

chr4:57217507

chr4:52864103

ENST00000343457

376_396

222

881.0

Transmembrane

Helical

Tgene

LRRC66

chr4:57217508

chr4:52864103

ENST00000343457

376_396

222

881.0

Transmembrane

Helical

Tgene

LRRC66

chr4:57217508

chr4:52869558

ENST00000343457

376_396

165

881.0

Transmembrane

Helical

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

AASDH

chr4:57217507

chr4:52864103

ENST00000205214

553_630

564

1099.0

Domain

Carrier

Hgene

AASDH

chr4:57217507

chr4:52864103

ENST00000451613

553_630

564

858.0

Domain

Carrier

Hgene

AASDH

chr4:57217507

chr4:52864103

ENST00000502617

553_630

564

842.0

Domain

Carrier

Hgene

AASDH

chr4:57217507

chr4:52864103

ENST00000513376

553_630

464

999.0

Domain

Carrier

Hgene

AASDH

chr4:57217508

chr4:52864103

ENST00000205214

553_630

564

1099.0

Domain

Carrier

Hgene

AASDH

chr4:57217508

chr4:52864103

ENST00000451613

553_630

564

858.0

Domain

Carrier

Hgene

AASDH

chr4:57217508

chr4:52864103

ENST00000502617

553_630

564

842.0

Domain

Carrier

Hgene

AASDH

chr4:57217508

chr4:52864103

ENST00000513376

553_630

464

999.0

Domain

Carrier

Hgene

AASDH

chr4:57217508

chr4:52869558

ENST00000205214

553_630

564

1099.0

Domain

Carrier

Hgene

AASDH

chr4:57217508

chr4:52869558

ENST00000451613

553_630

564

858.0

Domain

Carrier

Hgene

AASDH

chr4:57217508

chr4:52869558

ENST00000502617

553_630

564

842.0

Domain

Carrier

Hgene

AASDH

chr4:57217508

chr4:52869558

ENST00000513376

553_630

464

999.0

Domain

Carrier

Tgene

LRRC66

chr4:57217507

chr4:52864103

ENST00000343457

110_130

222

881.0

Repeat

Note=LRR 2

Tgene

LRRC66

chr4:57217507

chr4:52864103

ENST00000343457

149_171

222

881.0

Repeat

Note=LRR 3

Tgene

LRRC66

chr4:57217507

chr4:52864103

ENST00000343457

172_193

222

881.0

Repeat

Note=LRR 4

Tgene

LRRC66

chr4:57217507

chr4:52864103

ENST00000343457

196_217

222

881.0

Repeat

Note=LRR 5

Tgene

LRRC66

chr4:57217507

chr4:52864103

ENST00000343457

86_107

222

881.0

Repeat

Note=LRR 1

Tgene

LRRC66

chr4:57217508

chr4:52864103

ENST00000343457

110_130

222

881.0

Repeat

Note=LRR 2

Tgene

LRRC66

chr4:57217508

chr4:52864103

ENST00000343457

149_171

222

881.0

Repeat

Note=LRR 3

Tgene

LRRC66

chr4:57217508

chr4:52864103

ENST00000343457

172_193

222

881.0

Repeat

Note=LRR 4

Tgene

LRRC66

chr4:57217508

chr4:52864103

ENST00000343457

196_217

222

881.0

Repeat

Note=LRR 5

Tgene

LRRC66

chr4:57217508

chr4:52864103

ENST00000343457

86_107

222

881.0

Repeat

Note=LRR 1

Tgene

LRRC66

chr4:57217508

chr4:52869558

ENST00000343457

110_130

165

881.0

Repeat

Note=LRR 2

Tgene

LRRC66

chr4:57217508

chr4:52869558

ENST00000343457

149_171

165

881.0

Repeat

Note=LRR 3

Tgene

LRRC66

chr4:57217508

chr4:52869558

ENST00000343457

86_107

165

881.0

Repeat

Note=LRR 1

Tgene

LRRC66

chr4:57217507

chr4:52864103

ENST00000343457

4_24

222

881.0

Transmembrane

Helical

Tgene

LRRC66

chr4:57217508

chr4:52864103

ENST00000343457

4_24

222

881.0

Transmembrane

Helical

Tgene

LRRC66

chr4:57217508

chr4:52869558

ENST00000343457

4_24

165

881.0

Transmembrane

Helical

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Fusion Gene Sequence for AASDH-LRRC66

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>112_112_1_AASDH-LRRC66_AASDH_chr4_57217507_ENST00000434343_LRRC66_chr4_52864103_ENST00000343457_length(transcript)=3899nt_BP=1245nt
ATAGCTTTACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTA
ATCCGCGAGACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGAAATGACTCTTCAGGAATTGGTGCATAAGGCT
GCCTCCTGTTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCCAGTTTACTACACCTACAAGACTGTGGTTAAT
GCTGCTTCTGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGAAATTGGTCTCTACTGCCAACCTGGGATAGAC
TTACCCTCTTGGATTTTAGGAATTCTCCAAGTCCCGGCTGCTTATGTACCTATCGAGCCAGATTCACCACCGTCATTATCAACTCATTTT
ATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATTAATGGTACTTTTTGACATCACACAAGAAGATGTTTTGTTTCT
GGCTTCACCTCTGACCTTCGATCCTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCAACTTCCGT
CAAGTTGCTCCCATCAAAATTAGCCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTTAGAAGATT
TGGATCTCAGCTTATCAAGTCAACTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCATCATTGAC
AGTTCTCAGAAGCTGGAGAGGAGAAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCGACCATTTA
TAGGATTCCAGAGAAGACTCTTAACTCTACTCTCAAGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCAGTTACATGGTATAATCAG
GAAAAATTAATTCTCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAATATCTTCCAAGTCATGCA
GTCCCGGATGAGCTTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTAAACAAGATATATTTAAAC
TACATAAACTTGAAGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGGAAGGTCATAGACCTTAGC
AACAATGCTCTGATTACCATCCTACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTGGCTGATAATAACTGGCAG
TGTGATGATAGTGTGGCAGTCTTTCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGCAACAGGTCTATAGGGAGT
GAGGAGGCCAACGGGGGCACTCCCCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCATCGCATGAAAAGCCTCATA
AGGAGCAAAGCAGAGAGGCCCCAGGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCCGGCTCTGGTCTCAGGAAG
AAGCAGAGACGGCTGCCAAGGAGTGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCTCCCCAGGACCTGGCTCTG
GCGGTGTGCCTGTCAGTGTTCATCACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTTGACAGACTGTGGCAAAAA
AAGTGCCAGAGCAAAAGCCCTGGCCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCTGCGGGGCACACACCACAC
CCAGAGACCCATCTGCGCCAAGTATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACACAGCCACACCCACACGCC
ACCGTAATTCCTGATAGAACTCTGGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGCGGGGACAACACCGGGGCA
GGAAGTGGAAATGATGGTGCAGTCTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATGTCAGCAGCGCAGGACCAC
ATCCATAGGAATGATATTCTCGGAGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACATTCAGTGGGCGTCTCTTCT
GTAGCTGGCACGTCTCACGCTGTCTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCCGGAGAAATAACAGCTTCC
CTCTGTAAAATGCTAACACATGCAGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAGTCACTTTGGGACTCGCAG
ATGGAATTTTCTAAGGAAAGGCAAGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCCGGGGCAAGGGCTGAGGAA
GCGCTTTCAGCCCACTACAGCGAGGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCAAGATGGGACAGTGGCCTG
GATGTCACTCCTGCTAACAAGGAACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGTGACTGTGACTCTGATGAG
GGGTCTCTGTTCACTCTGAGCTCCATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGATGAGGAGTCCCTGCAGGAC
GAGAGCTCAGGGGCAAGCAAGGACAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACAATTCCAGGGAAATGCAAG
AATCAAGAAGATCCCTTTGAAAAACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAAAATGCCTCTGACACTGAT
AGATCTGAGGGCCTGTCACCCTGGCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATGTTCACTTATGATTATGAC
ACAGCTCTTCAATCCAAGGCAGCAGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTTTTACAGCAAACACCACCA
TGTTCTGCTGAAGTTCCCTCAGATCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAAGAATCTTTCATTAAGGAA
ATATTCACAGCTCTAAACAATATTCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATCCTGAAGGAGACAACATGA
ATTCCAACCAAGTGGACACTGATGCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGGTTATAAGCTAAACACACT
TGTTAACATCCTATGGGGATGAACCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTCCAAGAACCATGCACCATT
ATTACAAGAGCTCCAAACAAAACCAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATATTCAGAAGAGAATCTGTT
GCAGTTAGACGAAGTGGTTCTAACTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCTCTGAAAAGAACAGCTTTA
GGATGACAAAGACAAGGATGTTCAACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGAAGCACTTAAGTGGAAATG
CTGGATAGATTTTAATGAATTCTGAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAATTGGAAAAGTTCTGAGTA

>112_112_1_AASDH-LRRC66_AASDH_chr4_57217507_ENST00000434343_LRRC66_chr4_52864103_ENST00000343457_length(amino acids)=737AA_BP=79
MVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNYINLKSENKLSGKEDLWEKLQYLWKVIDLSNNALIT
ILPMMIIALEFPHLVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSRISRETRLPPIHLHRMKSLIRSKAER
PQGGRHTGISTLGKKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFLVAFSLGAFTRPYVDRLWQKKCQSKS
PGLDNAYSNEGFYDDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRSRKDPGSSQSPGQCGDNTGAGSGNDG
AVYSILQRHPHAGNRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGSSRYDSNELDPSLSGEITASLCKMLT
HAEAQRTGDSKERGGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPYGDPRDTGPSVFPPRWDSGLDVTPAN
KEPVQKSTPSDTCCELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVTAVDSLEENVTFQTIPGKCKNQEDPF
EKPLISAPDSGMYKTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWHCSLRDLEFSNVDVLQQTPPCSAEVP

--------------------------------------------------------------
>112_112_2_AASDH-LRRC66_AASDH_chr4_57217507_ENST00000513376_LRRC66_chr4_52864103_ENST00000343457_length(transcript)=4178nt_BP=1524nt
CCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGAGACTTGCTAAAATTCTCCAAGTCCCGGCTGCTTATGTA
CCTATCGAGCCAGATTCACCACCGTCATTATCAACTCATTTTATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATT
AATAAATTTAAATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGG
AAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAAT
GAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAG
ATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGGGTACTTTTTGACATCACACAAGAAGATGTTTTGTTTCTG
GCTTCACCTCTGACCTTCGATCCTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCAACTTCCGTC
AAGTTGCTCCCATCAAAATTAGCCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTTAGAAGATTT
GGATCTCAGCTTATCAAGTCAACTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCATCATTGACA
GTTCTCAGAAGCTGGAGAGGAGAAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCGACCATTTAT
AGGATTCCAGAGAAGACTCTTAACTCTACTCTCAAATGTGAATTGCCTGTACAACTGGGATTTCCACTTCTTGGAACAGTAGTTGAAGTC
AGAGATACTAATGGCTTCACAATTCAGGAAGGCAGTGGCCAAGTATTTTTAGGTGGCAGAAACAGAGTGTGTTTTCTTGATGATGAAGTG
ACAGTACCACTTGGCACAATGCGAGCTACAGGAGACTTTGTGACTGTGAAAGATGGAGAGATTTTTTTTTTGGGACGAAAAGACAGTCAG
ATCAAACGTCATGGCAAACGTCTTAACATTGAACTTGTGCAACAGGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCAGTTACATGG
TATAATCAGGAAAAATTAATTCTCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAATATCTTCCA
AGTCATGCAGTCCCGGATGAGCTTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTAAACAAGATA
TATTTAAACTACATAAACTTGAAGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGGAAGGTCATA
GACCTTAGCAACAATGCTCTGATTACCATCCTACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTGGCTGATAAT
AACTGGCAGTGTGATGATAGTGTGGCAGTCTTTCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGCAACAGGTCT
ATAGGGAGTGAGGAGGCCAACGGGGGCACTCCCCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCATCGCATGAAA
AGCCTCATAAGGAGCAAAGCAGAGAGGCCCCAGGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCCGGCTCTGGT
CTCAGGAAGAAGCAGAGACGGCTGCCAAGGAGTGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCTCCCCAGGAC
CTGGCTCTGGCGGTGTGCCTGTCAGTGTTCATCACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTTGACAGACTG
TGGCAAAAAAAGTGCCAGAGCAAAAGCCCTGGCCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCTGCGGGGCAC
ACACCACACCCAGAGACCCATCTGCGCCAAGTATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACACAGCCACAC
CCACACGCCACCGTAATTCCTGATAGAACTCTGGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGCGGGGACAAC
ACCGGGGCAGGAAGTGGAAATGATGGTGCAGTCTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATGTCAGCAGCG
CAGGACCACATCCATAGGAATGATATTCTCGGAGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACATTCAGTGGGC
GTCTCTTCTGTAGCTGGCACGTCTCACGCTGTCTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCCGGAGAAATA
ACAGCTTCCCTCTGTAAAATGCTAACACATGCAGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAGTCACTTTGG
GACTCGCAGATGGAATTTTCTAAGGAAAGGCAAGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCCGGGGCAAGG
GCTGAGGAAGCGCTTTCAGCCCACTACAGCGAGGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCAAGATGGGAC
AGTGGCCTGGATGTCACTCCTGCTAACAAGGAACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGTGACTGTGAC
TCTGATGAGGGGTCTCTGTTCACTCTGAGCTCCATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGATGAGGAGTCC
CTGCAGGACGAGAGCTCAGGGGCAAGCAAGGACAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACAATTCCAGGG
AAATGCAAGAATCAAGAAGATCCCTTTGAAAAACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAAAATGCCTCT
GACACTGATAGATCTGAGGGCCTGTCACCCTGGCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATGTTCACTTAT
GATTATGACACAGCTCTTCAATCCAAGGCAGCAGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTTTTACAGCAA
ACACCACCATGTTCTGCTGAAGTTCCCTCAGATCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAAGAATCTTTC
ATTAAGGAAATATTCACAGCTCTAAACAATATTCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATCCTGAAGGAG
ACAACATGAATTCCAACCAAGTGGACACTGATGCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGGTTATAAGCT
AAACACACTTGTTAACATCCTATGGGGATGAACCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTCCAAGAACCA
TGCACCATTATTACAAGAGCTCCAAACAAAACCAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATATTCAGAAGA
GAATCTGTTGCAGTTAGACGAAGTGGTTCTAACTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCTCTGAAAAGA
ACAGCTTTAGGATGACAAAGACAAGGATGTTCAACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGAAGCACTTAA
GTGGAAATGCTGGATAGATTTTAATGAATTCTGAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAATTGGAAAAG

>112_112_2_AASDH-LRRC66_AASDH_chr4_57217507_ENST00000513376_LRRC66_chr4_52864103_ENST00000343457_length(amino acids)=1122AA_BP=0
MKKCNLKYILVEKKQINKFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKH
CLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSH
HRVTVLQATPTLLRRFGSQLIKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLNSTLKCE
LPVQLGFPLLGTVVEVRDTNGFTIQEGSGQVFLGGRNRVCFLDDEVTVPLGTMRATGDFVTVKDGEIFFLGRKDSQIKRHGKRLNIELVQ
QVAEELQQVESCAVTWYNQEKLILFMVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNYINLKSENKLS
GKEDLWEKLQYLWKVIDLSNNALITILPMMIIALEFPHLVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSR
ISRETRLPPIHLHRMKSLIRSKAERPQGGRHTGISTLGKKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFL
VAFSLGAFTRPYVDRLWQKKCQSKSPGLDNAYSNEGFYDDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRS
RKDPGSSQSPGQCGDNTGAGSGNDGAVYSILQRHPHAGNRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGS
SRYDSNELDPSLSGEITASLCKMLTHAEAQRTGDSKERGGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPY
GDPRDTGPSVFPPRWDSGLDVTPANKEPVQKSTPSDTCCELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVT
AVDSLEENVTFQTIPGKCKNQEDPFEKPLISAPDSGMYKTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWH

--------------------------------------------------------------
>112_112_3_AASDH-LRRC66_AASDH_chr4_57217507_ENST00000602986_LRRC66_chr4_52864103_ENST00000343457_length(transcript)=4367nt_BP=1713nt
ACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGA
GACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGAAATGACTCTTCAGGAATTGGTGCATAAGGCTGCCTCCTG
TTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCCAGTTTACTACACCTACAAGACTGTGGTTAATGCTGCTTC
TGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGAAATTGGTCTCTACTGCCAACCTGGGATAGACTTACCCTC
TTGGATTTTAGGAAATTTAAATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGA
CTTCACTGGAAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAG
CATGTCAATGAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGG
ATACCGAAGATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGGGTACTTTTTGACATCACACAAGAAGATGTT
TTGTTTCTGGCTTCACCTCTGACCTTCGATCCTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCA
ACTTCCGTCAAGTTGCTCCCATCAAAATTAGCCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTT
AGAAGATTTGGATCTCAGCTTATCAAGTCAACTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCA
TCATTGACAGTTCTCAGAAGCTGGAGAGGAGAAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCG
ACCATTTATAGGATTCCAGAGAAGACTCTTAACTCTACTCTCAAATGTGAATTGCCTGTACAACTGGGATTTCCACTTCTTGGAACAGTA
GTTGAAGTCAGAGATACTAATGGCTTCACAATTCAGGAAGGCAGTGGCCAAGTATTTTTAGGTGGCAGAAACAGAGTGTGTTTTCTTGAT
GATGAAGTGACAGTACCACTTGGCACAATGCGAGCTACAGGAGACTTTGTGACTGTGAAAGATGGAGAGATTTTTTTTTTGGGACGAAAA
GACAGTCAGATCAAACGTCATGGCAAACGTCTTAACATTGAACTTGTGCAACAGGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCA
GTTACATGGTATAATCAGGAAAAATTAATTCTCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAA
TATCTTCCAAGTCATGCAGTCCCGGATGAGCTTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTA
AACAAGATATATTTAAACTACATAAACTTGAAGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGG
AAGGTCATAGACCTTAGCAACAATGCTCTGATTACCATCCTACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTG
GCTGATAATAACTGGCAGTGTGATGATAGTGTGGCAGTCTTTCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGC
AACAGGTCTATAGGGAGTGAGGAGGCCAACGGGGGCACTCCCCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCAT
CGCATGAAAAGCCTCATAAGGAGCAAAGCAGAGAGGCCCCAGGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCC
GGCTCTGGTCTCAGGAAGAAGCAGAGACGGCTGCCAAGGAGTGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCT
CCCCAGGACCTGGCTCTGGCGGTGTGCCTGTCAGTGTTCATCACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTT
GACAGACTGTGGCAAAAAAAGTGCCAGAGCAAAAGCCCTGGCCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCT
GCGGGGCACACACCACACCCAGAGACCCATCTGCGCCAAGTATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACA
CAGCCACACCCACACGCCACCGTAATTCCTGATAGAACTCTGGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGC
GGGGACAACACCGGGGCAGGAAGTGGAAATGATGGTGCAGTCTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATG
TCAGCAGCGCAGGACCACATCCATAGGAATGATATTCTCGGAGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACAT
TCAGTGGGCGTCTCTTCTGTAGCTGGCACGTCTCACGCTGTCTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCC
GGAGAAATAACAGCTTCCCTCTGTAAAATGCTAACACATGCAGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAG
TCACTTTGGGACTCGCAGATGGAATTTTCTAAGGAAAGGCAAGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCC
GGGGCAAGGGCTGAGGAAGCGCTTTCAGCCCACTACAGCGAGGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCA
AGATGGGACAGTGGCCTGGATGTCACTCCTGCTAACAAGGAACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGT
GACTGTGACTCTGATGAGGGGTCTCTGTTCACTCTGAGCTCCATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGAT
GAGGAGTCCCTGCAGGACGAGAGCTCAGGGGCAAGCAAGGACAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACA
ATTCCAGGGAAATGCAAGAATCAAGAAGATCCCTTTGAAAAACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAA
AATGCCTCTGACACTGATAGATCTGAGGGCCTGTCACCCTGGCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATG
TTCACTTATGATTATGACACAGCTCTTCAATCCAAGGCAGCAGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTT
TTACAGCAAACACCACCATGTTCTGCTGAAGTTCCCTCAGATCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAA
GAATCTTTCATTAAGGAAATATTCACAGCTCTAAACAATATTCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATC
CTGAAGGAGACAACATGAATTCCAACCAAGTGGACACTGATGCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGG
TTATAAGCTAAACACACTTGTTAACATCCTATGGGGATGAACCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTC
CAAGAACCATGCACCATTATTACAAGAGCTCCAAACAAAACCAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATA
TTCAGAAGAGAATCTGTTGCAGTTAGACGAAGTGGTTCTAACTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCT
CTGAAAAGAACAGCTTTAGGATGACAAAGACAAGGATGTTCAACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGA
AGCACTTAAGTGGAAATGCTGGATAGATTTTAATGAATTCTGAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAA

>112_112_3_AASDH-LRRC66_AASDH_chr4_57217507_ENST00000602986_LRRC66_chr4_52864103_ENST00000343457_length(amino acids)=1118AA_BP=1
MPTWDRLTLLDFRKFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKHCLAY
VLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVT
VLQATPTLLRRFGSQLIKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLNSTLKCELPVQ
LGFPLLGTVVEVRDTNGFTIQEGSGQVFLGGRNRVCFLDDEVTVPLGTMRATGDFVTVKDGEIFFLGRKDSQIKRHGKRLNIELVQQVAE
ELQQVESCAVTWYNQEKLILFMVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNYINLKSENKLSGKED
LWEKLQYLWKVIDLSNNALITILPMMIIALEFPHLVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSRISRE
TRLPPIHLHRMKSLIRSKAERPQGGRHTGISTLGKKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFLVAFS
LGAFTRPYVDRLWQKKCQSKSPGLDNAYSNEGFYDDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRSRKDP
GSSQSPGQCGDNTGAGSGNDGAVYSILQRHPHAGNRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGSSRYD
SNELDPSLSGEITASLCKMLTHAEAQRTGDSKERGGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPYGDPR
DTGPSVFPPRWDSGLDVTPANKEPVQKSTPSDTCCELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVTAVDS
LEENVTFQTIPGKCKNQEDPFEKPLISAPDSGMYKTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWHCSLR

--------------------------------------------------------------
>112_112_4_AASDH-LRRC66_AASDH_chr4_57217508_ENST00000205214_LRRC66_chr4_52869558_ENST00000343457_length(transcript)=4697nt_BP=1873nt
GGAAGATTTACGTATGGTGCCTCGCTCTGGGATAGCTTTACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTA
TCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGAGACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGA
AATGACTCTTCAGGAATTGGTGCATAAGGCTGCCTCCTGTTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCC
AGTTTACTACACCTACAAGACTGTGGTTAATGCTGCTTCTGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGA
AATTGGTCTCTACTGCCAACCTGGGATAGACTTACCCTCTTGGATTTTAGGAATTCTCCAAGTCCCGGCTGCTTATGTACCTATCGAGCC
AGATTCACCACCGTCATTATCAACTCATTTTATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATTAATAAATTTAA
ATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGGAAAAATACTGA
GGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAATGAAGAAAAAGC
AGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAGATTGTCAGAGT
GCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGGGTACTTTTTGACATCACACAAGAAGATGTTTTGTTTCTGGCTTCACCTCT
GACCTTCGATCCTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCAACTTCCGTCAAGTTGCTCCC
ATCAAAATTAGCCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTTAGAAGATTTGGATCTCAGCT
TATCAAGTCAACTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCATCATTGACAGTTCTCAGAAG
CTGGAGAGGAGAAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCGACCATTTATAGGATTCCAGA
GAAGACTCTTAACTCTACTCTCAAATGTGAATTGCCTGTACAACTGGGATTTCCACTTCTTGGAACAGTAGTTGAAGTCAGAGATACTAA
TGGCTTCACAATTCAGGAAGGCAGTGGCCAAGTATTTTTAGGTGGCAGAAACAGAGTGTGTTTTCTTGATGATGAAGTGACAGTACCACT
TGGCACAATGCGAGCTACAGGAGACTTTGTGACTGTGAAAGATGGAGAGATTTTTTTTTTGGGACGAAAAGACAGTCAGATCAAACGTCA
TGGCAAACGTCTTAACATTGAACTTGTGCAACAGGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCAGTTACATGGTATAATCAGGA
AAAATTAATTCTCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAATATCTTCCAAGTCATGCAGT
CCCGGATGAGCTTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTAAACAAGATATATTTAAACTA
CATAAACTTGAAGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGGAAGGACTGTGGAAACTGAAG
TCATTGCAGAGTTTGGATCTGTCATTCAATGGGATATTGCAAATAGGGTGGTCTGATTTTCACAACTGCCTGCAACTGGAGAATCTCTGT
TTAAAGAGCAACAAGATATTCAAAATTCCCCCACAAGCCTTCAAGGACCTCAAAAAATTACAGGTCATAGACCTTAGCAACAATGCTCTG
ATTACCATCCTACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTGGCTGATAATAACTGGCAGTGTGATGATAGT
GTGGCAGTCTTTCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGCAACAGGTCTATAGGGAGTGAGGAGGCCAAC
GGGGGCACTCCCCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCATCGCATGAAAAGCCTCATAAGGAGCAAAGCA
GAGAGGCCCCAGGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCCGGCTCTGGTCTCAGGAAGAAGCAGAGACGG
CTGCCAAGGAGTGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCTCCCCAGGACCTGGCTCTGGCGGTGTGCCTG
TCAGTGTTCATCACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTTGACAGACTGTGGCAAAAAAAGTGCCAGAGC
AAAAGCCCTGGCCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCTGCGGGGCACACACCACACCCAGAGACCCAT
CTGCGCCAAGTATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACACAGCCACACCCACACGCCACCGTAATTCCT
GATAGAACTCTGGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGCGGGGACAACACCGGGGCAGGAAGTGGAAAT
GATGGTGCAGTCTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATGTCAGCAGCGCAGGACCACATCCATAGGAAT
GATATTCTCGGAGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACATTCAGTGGGCGTCTCTTCTGTAGCTGGCACG
TCTCACGCTGTCTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCCGGAGAAATAACAGCTTCCCTCTGTAAAATG
CTAACACATGCAGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAGTCACTTTGGGACTCGCAGATGGAATTTTCT
AAGGAAAGGCAAGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCCGGGGCAAGGGCTGAGGAAGCGCTTTCAGCC
CACTACAGCGAGGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCAAGATGGGACAGTGGCCTGGATGTCACTCCT
GCTAACAAGGAACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGTGACTGTGACTCTGATGAGGGGTCTCTGTTC
ACTCTGAGCTCCATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGATGAGGAGTCCCTGCAGGACGAGAGCTCAGGG
GCAAGCAAGGACAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACAATTCCAGGGAAATGCAAGAATCAAGAAGAT
CCCTTTGAAAAACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAAAATGCCTCTGACACTGATAGATCTGAGGGC
CTGTCACCCTGGCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATGTTCACTTATGATTATGACACAGCTCTTCAA
TCCAAGGCAGCAGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTTTTACAGCAAACACCACCATGTTCTGCTGAA
GTTCCCTCAGATCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAAGAATCTTTCATTAAGGAAATATTCACAGCT
CTAAACAATATTCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATCCTGAAGGAGACAACATGAATTCCAACCAAG
TGGACACTGATGCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGGTTATAAGCTAAACACACTTGTTAACATCCT
ATGGGGATGAACCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTCCAAGAACCATGCACCATTATTACAAGAGCT
CCAAACAAAACCAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATATTCAGAAGAGAATCTGTTGCAGTTAGACGA
AGTGGTTCTAACTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCTCTGAAAAGAACAGCTTTAGGATGACAAAGA
CAAGGATGTTCAACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGAAGCACTTAAGTGGAAATGCTGGATAGATTT
TAATGAATTCTGAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAATTGGAAAAGTTCTGAGTAAATATAAATGTT

>112_112_4_AASDH-LRRC66_AASDH_chr4_57217508_ENST00000205214_LRRC66_chr4_52869558_ENST00000343457_length(amino acids)=724AA_BP=9
MGKITVFVEGLWKLKSLQSLDLSFNGILQIGWSDFHNCLQLENLCLKSNKIFKIPPQAFKDLKKLQVIDLSNNALITILPMMIIALEFPH
LVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSRISRETRLPPIHLHRMKSLIRSKAERPQGGRHTGISTLG
KKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFLVAFSLGAFTRPYVDRLWQKKCQSKSPGLDNAYSNEGFY
DDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRSRKDPGSSQSPGQCGDNTGAGSGNDGAVYSILQRHPHAG
NRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGSSRYDSNELDPSLSGEITASLCKMLTHAEAQRTGDSKER
GGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPYGDPRDTGPSVFPPRWDSGLDVTPANKEPVQKSTPSDTC
CELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVTAVDSLEENVTFQTIPGKCKNQEDPFEKPLISAPDSGMY
KTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWHCSLRDLEFSNVDVLQQTPPCSAEVPSDPDKAAFHERDS

--------------------------------------------------------------
>112_112_5_AASDH-LRRC66_AASDH_chr4_57217508_ENST00000434343_LRRC66_chr4_52864103_ENST00000343457_length(transcript)=3899nt_BP=1245nt
ATAGCTTTACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTA
ATCCGCGAGACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGAAATGACTCTTCAGGAATTGGTGCATAAGGCT
GCCTCCTGTTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCCAGTTTACTACACCTACAAGACTGTGGTTAAT
GCTGCTTCTGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGAAATTGGTCTCTACTGCCAACCTGGGATAGAC
TTACCCTCTTGGATTTTAGGAATTCTCCAAGTCCCGGCTGCTTATGTACCTATCGAGCCAGATTCACCACCGTCATTATCAACTCATTTT
ATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATTAATGGTACTTTTTGACATCACACAAGAAGATGTTTTGTTTCT
GGCTTCACCTCTGACCTTCGATCCTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCAACTTCCGT
CAAGTTGCTCCCATCAAAATTAGCCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTTAGAAGATT
TGGATCTCAGCTTATCAAGTCAACTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCATCATTGAC
AGTTCTCAGAAGCTGGAGAGGAGAAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCGACCATTTA
TAGGATTCCAGAGAAGACTCTTAACTCTACTCTCAAGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCAGTTACATGGTATAATCAG
GAAAAATTAATTCTCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAATATCTTCCAAGTCATGCA
GTCCCGGATGAGCTTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTAAACAAGATATATTTAAAC
TACATAAACTTGAAGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGGAAGGTCATAGACCTTAGC
AACAATGCTCTGATTACCATCCTACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTGGCTGATAATAACTGGCAG
TGTGATGATAGTGTGGCAGTCTTTCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGCAACAGGTCTATAGGGAGT
GAGGAGGCCAACGGGGGCACTCCCCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCATCGCATGAAAAGCCTCATA
AGGAGCAAAGCAGAGAGGCCCCAGGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCCGGCTCTGGTCTCAGGAAG
AAGCAGAGACGGCTGCCAAGGAGTGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCTCCCCAGGACCTGGCTCTG
GCGGTGTGCCTGTCAGTGTTCATCACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTTGACAGACTGTGGCAAAAA
AAGTGCCAGAGCAAAAGCCCTGGCCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCTGCGGGGCACACACCACAC
CCAGAGACCCATCTGCGCCAAGTATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACACAGCCACACCCACACGCC
ACCGTAATTCCTGATAGAACTCTGGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGCGGGGACAACACCGGGGCA
GGAAGTGGAAATGATGGTGCAGTCTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATGTCAGCAGCGCAGGACCAC
ATCCATAGGAATGATATTCTCGGAGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACATTCAGTGGGCGTCTCTTCT
GTAGCTGGCACGTCTCACGCTGTCTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCCGGAGAAATAACAGCTTCC
CTCTGTAAAATGCTAACACATGCAGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAGTCACTTTGGGACTCGCAG
ATGGAATTTTCTAAGGAAAGGCAAGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCCGGGGCAAGGGCTGAGGAA
GCGCTTTCAGCCCACTACAGCGAGGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCAAGATGGGACAGTGGCCTG
GATGTCACTCCTGCTAACAAGGAACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGTGACTGTGACTCTGATGAG
GGGTCTCTGTTCACTCTGAGCTCCATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGATGAGGAGTCCCTGCAGGAC
GAGAGCTCAGGGGCAAGCAAGGACAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACAATTCCAGGGAAATGCAAG
AATCAAGAAGATCCCTTTGAAAAACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAAAATGCCTCTGACACTGAT
AGATCTGAGGGCCTGTCACCCTGGCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATGTTCACTTATGATTATGAC
ACAGCTCTTCAATCCAAGGCAGCAGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTTTTACAGCAAACACCACCA
TGTTCTGCTGAAGTTCCCTCAGATCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAAGAATCTTTCATTAAGGAA
ATATTCACAGCTCTAAACAATATTCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATCCTGAAGGAGACAACATGA
ATTCCAACCAAGTGGACACTGATGCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGGTTATAAGCTAAACACACT
TGTTAACATCCTATGGGGATGAACCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTCCAAGAACCATGCACCATT
ATTACAAGAGCTCCAAACAAAACCAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATATTCAGAAGAGAATCTGTT
GCAGTTAGACGAAGTGGTTCTAACTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCTCTGAAAAGAACAGCTTTA
GGATGACAAAGACAAGGATGTTCAACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGAAGCACTTAAGTGGAAATG
CTGGATAGATTTTAATGAATTCTGAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAATTGGAAAAGTTCTGAGTA

>112_112_5_AASDH-LRRC66_AASDH_chr4_57217508_ENST00000434343_LRRC66_chr4_52864103_ENST00000343457_length(amino acids)=737AA_BP=79
MVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNYINLKSENKLSGKEDLWEKLQYLWKVIDLSNNALIT
ILPMMIIALEFPHLVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSRISRETRLPPIHLHRMKSLIRSKAER
PQGGRHTGISTLGKKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFLVAFSLGAFTRPYVDRLWQKKCQSKS
PGLDNAYSNEGFYDDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRSRKDPGSSQSPGQCGDNTGAGSGNDG
AVYSILQRHPHAGNRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGSSRYDSNELDPSLSGEITASLCKMLT
HAEAQRTGDSKERGGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPYGDPRDTGPSVFPPRWDSGLDVTPAN
KEPVQKSTPSDTCCELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVTAVDSLEENVTFQTIPGKCKNQEDPF
EKPLISAPDSGMYKTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWHCSLRDLEFSNVDVLQQTPPCSAEVP

--------------------------------------------------------------
>112_112_6_AASDH-LRRC66_AASDH_chr4_57217508_ENST00000451613_LRRC66_chr4_52869558_ENST00000343457_length(transcript)=4686nt_BP=1862nt
GTATGGTGCCTCGCTCTGGGATAGCTTTACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTATCCGGGAAAGG
GCCGAATGCGATCAAACCTAATCCGCGAGACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGAAATGACTCTTC
AGGAATTGGTGCATAAGGCTGCCTCCTGTTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCCAGTTTACTACA
CCTACAAGACTGTGGTTAATGCTGCTTCTGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGAAATTGGTCTCT
ACTGCCAACCTGGGATAGACTTACCCTCTTGGATTTTAGGAATTCTCCAAGTCCCGGCTGCTTATGTACCTATCGAGCCAGATTCACCAC
CGTCATTATCAACTCATTTTATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATTAATAAATTTAAATCTTTTCATG
AAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGGAAAAATACTGAGGTGAACTTGA
TGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAATGAAGAAAAAGCAGAAGAACACA
TGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAGATTGTCAGAGTGCCTCATAAGT
GTATAGTACCAAATATCCAGCATTTTCGGGTACTTTTTGACATCACACAAGAAGATGTTTTGTTTCTGGCTTCACCTCTGACCTTCGATC
CTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCAACTTCCGTCAAGTTGCTCCCATCAAAATTAG
CCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTTAGAAGATTTGGATCTCAGCTTATCAAGTCAA
CTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCATCATTGACAGTTCTCAGAAGCTGGAGAGGAG
AAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCGACCATTTATAGGATTCCAGAGAAGACTCTTA
ACTCTACTCTCAAATGTGAATTGCCTGTACAACTGGGATTTCCACTTCTTGGAACAGTAGTTGAAGTCAGAGATACTAATGGCTTCACAA
TTCAGGAAGGCAGTGGCCAAGTATTTTTAGGTGGCAGAAACAGAGTGTGTTTTCTTGATGATGAAGTGACAGTACCACTTGGCACAATGC
GAGCTACAGGAGACTTTGTGACTGTGAAAGATGGAGAGATTTTTTTTTTGGGACGAAAAGACAGTCAGATCAAACGTCATGGCAAACGTC
TTAACATTGAACTTGTGCAACAGGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCAGTTACATGGTATAATCAGGAAAAATTAATTC
TCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAATATCTTCCAAGTCATGCAGTCCCGGATGAGC
TTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTAAACAAGATATATTTAAACTACATAAACTTGA
AGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGGAAGGACTGTGGAAACTGAAGTCATTGCAGAG
TTTGGATCTGTCATTCAATGGGATATTGCAAATAGGGTGGTCTGATTTTCACAACTGCCTGCAACTGGAGAATCTCTGTTTAAAGAGCAA
CAAGATATTCAAAATTCCCCCACAAGCCTTCAAGGACCTCAAAAAATTACAGGTCATAGACCTTAGCAACAATGCTCTGATTACCATCCT
ACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTGGCTGATAATAACTGGCAGTGTGATGATAGTGTGGCAGTCTT
TCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGCAACAGGTCTATAGGGAGTGAGGAGGCCAACGGGGGCACTCC
CCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCATCGCATGAAAAGCCTCATAAGGAGCAAAGCAGAGAGGCCCCA
GGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCCGGCTCTGGTCTCAGGAAGAAGCAGAGACGGCTGCCAAGGAG
TGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCTCCCCAGGACCTGGCTCTGGCGGTGTGCCTGTCAGTGTTCAT
CACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTTGACAGACTGTGGCAAAAAAAGTGCCAGAGCAAAAGCCCTGG
CCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCTGCGGGGCACACACCACACCCAGAGACCCATCTGCGCCAAGT
ATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACACAGCCACACCCACACGCCACCGTAATTCCTGATAGAACTCT
GGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGCGGGGACAACACCGGGGCAGGAAGTGGAAATGATGGTGCAGT
CTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATGTCAGCAGCGCAGGACCACATCCATAGGAATGATATTCTCGG
AGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACATTCAGTGGGCGTCTCTTCTGTAGCTGGCACGTCTCACGCTGT
CTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCCGGAGAAATAACAGCTTCCCTCTGTAAAATGCTAACACATGC
AGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAGTCACTTTGGGACTCGCAGATGGAATTTTCTAAGGAAAGGCA
AGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCCGGGGCAAGGGCTGAGGAAGCGCTTTCAGCCCACTACAGCGA
GGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCAAGATGGGACAGTGGCCTGGATGTCACTCCTGCTAACAAGGA
ACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGTGACTGTGACTCTGATGAGGGGTCTCTGTTCACTCTGAGCTC
CATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGATGAGGAGTCCCTGCAGGACGAGAGCTCAGGGGCAAGCAAGGA
CAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACAATTCCAGGGAAATGCAAGAATCAAGAAGATCCCTTTGAAAA
ACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAAAATGCCTCTGACACTGATAGATCTGAGGGCCTGTCACCCTG
GCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATGTTCACTTATGATTATGACACAGCTCTTCAATCCAAGGCAGC
AGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTTTTACAGCAAACACCACCATGTTCTGCTGAAGTTCCCTCAGA
TCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAAGAATCTTTCATTAAGGAAATATTCACAGCTCTAAACAATAT
TCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATCCTGAAGGAGACAACATGAATTCCAACCAAGTGGACACTGAT
GCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGGTTATAAGCTAAACACACTTGTTAACATCCTATGGGGATGAA
CCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTCCAAGAACCATGCACCATTATTACAAGAGCTCCAAACAAAAC
CAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATATTCAGAAGAGAATCTGTTGCAGTTAGACGAAGTGGTTCTAA
CTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCTCTGAAAAGAACAGCTTTAGGATGACAAAGACAAGGATGTTC
AACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGAAGCACTTAAGTGGAAATGCTGGATAGATTTTAATGAATTCT
GAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAATTGGAAAAGTTCTGAGTAAATATAAATGTTTTTAAATAAGT

>112_112_6_AASDH-LRRC66_AASDH_chr4_57217508_ENST00000451613_LRRC66_chr4_52869558_ENST00000343457_length(amino acids)=724AA_BP=9
MGKITVFVEGLWKLKSLQSLDLSFNGILQIGWSDFHNCLQLENLCLKSNKIFKIPPQAFKDLKKLQVIDLSNNALITILPMMIIALEFPH
LVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSRISRETRLPPIHLHRMKSLIRSKAERPQGGRHTGISTLG
KKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFLVAFSLGAFTRPYVDRLWQKKCQSKSPGLDNAYSNEGFY
DDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRSRKDPGSSQSPGQCGDNTGAGSGNDGAVYSILQRHPHAG
NRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGSSRYDSNELDPSLSGEITASLCKMLTHAEAQRTGDSKER
GGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPYGDPRDTGPSVFPPRWDSGLDVTPANKEPVQKSTPSDTC
CELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVTAVDSLEENVTFQTIPGKCKNQEDPFEKPLISAPDSGMY
KTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWHCSLRDLEFSNVDVLQQTPPCSAEVPSDPDKAAFHERDS

--------------------------------------------------------------
>112_112_7_AASDH-LRRC66_AASDH_chr4_57217508_ENST00000502617_LRRC66_chr4_52869558_ENST00000343457_length(transcript)=4697nt_BP=1873nt
GGAAGATTTACGTATGGTGCCTCGCTCTGGGATAGCTTTACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTA
TCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGAGACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGA
AATGACTCTTCAGGAATTGGTGCATAAGGCTGCCTCCTGTTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCC
AGTTTACTACACCTACAAGACTGTGGTTAATGCTGCTTCTGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGA
AATTGGTCTCTACTGCCAACCTGGGATAGACTTACCCTCTTGGATTTTAGGAATTCTCCAAGTCCCGGCTGCTTATGTACCTATCGAGCC
AGATTCACCACCGTCATTATCAACTCATTTTATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATTAATAAATTTAA
ATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGGAAAAATACTGA
GGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAATGAAGAAAAAGC
AGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAGATTGTCAGAGT
GCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGGGTACTTTTTGACATCACACAAGAAGATGTTTTGTTTCTGGCTTCACCTCT
GACCTTCGATCCTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCAACTTCCGTCAAGTTGCTCCC
ATCAAAATTAGCCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTTAGAAGATTTGGATCTCAGCT
TATCAAGTCAACTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCATCATTGACAGTTCTCAGAAG
CTGGAGAGGAGAAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCGACCATTTATAGGATTCCAGA
GAAGACTCTTAACTCTACTCTCAAATGTGAATTGCCTGTACAACTGGGATTTCCACTTCTTGGAACAGTAGTTGAAGTCAGAGATACTAA
TGGCTTCACAATTCAGGAAGGCAGTGGCCAAGTATTTTTAGGTGGCAGAAACAGAGTGTGTTTTCTTGATGATGAAGTGACAGTACCACT
TGGCACAATGCGAGCTACAGGAGACTTTGTGACTGTGAAAGATGGAGAGATTTTTTTTTTGGGACGAAAAGACAGTCAGATCAAACGTCA
TGGCAAACGTCTTAACATTGAACTTGTGCAACAGGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCAGTTACATGGTATAATCAGGA
AAAATTAATTCTCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAATATCTTCCAAGTCATGCAGT
CCCGGATGAGCTTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTAAACAAGATATATTTAAACTA
CATAAACTTGAAGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGGAAGGACTGTGGAAACTGAAG
TCATTGCAGAGTTTGGATCTGTCATTCAATGGGATATTGCAAATAGGGTGGTCTGATTTTCACAACTGCCTGCAACTGGAGAATCTCTGT
TTAAAGAGCAACAAGATATTCAAAATTCCCCCACAAGCCTTCAAGGACCTCAAAAAATTACAGGTCATAGACCTTAGCAACAATGCTCTG
ATTACCATCCTACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTGGCTGATAATAACTGGCAGTGTGATGATAGT
GTGGCAGTCTTTCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGCAACAGGTCTATAGGGAGTGAGGAGGCCAAC
GGGGGCACTCCCCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCATCGCATGAAAAGCCTCATAAGGAGCAAAGCA
GAGAGGCCCCAGGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCCGGCTCTGGTCTCAGGAAGAAGCAGAGACGG
CTGCCAAGGAGTGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCTCCCCAGGACCTGGCTCTGGCGGTGTGCCTG
TCAGTGTTCATCACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTTGACAGACTGTGGCAAAAAAAGTGCCAGAGC
AAAAGCCCTGGCCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCTGCGGGGCACACACCACACCCAGAGACCCAT
CTGCGCCAAGTATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACACAGCCACACCCACACGCCACCGTAATTCCT
GATAGAACTCTGGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGCGGGGACAACACCGGGGCAGGAAGTGGAAAT
GATGGTGCAGTCTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATGTCAGCAGCGCAGGACCACATCCATAGGAAT
GATATTCTCGGAGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACATTCAGTGGGCGTCTCTTCTGTAGCTGGCACG
TCTCACGCTGTCTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCCGGAGAAATAACAGCTTCCCTCTGTAAAATG
CTAACACATGCAGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAGTCACTTTGGGACTCGCAGATGGAATTTTCT
AAGGAAAGGCAAGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCCGGGGCAAGGGCTGAGGAAGCGCTTTCAGCC
CACTACAGCGAGGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCAAGATGGGACAGTGGCCTGGATGTCACTCCT
GCTAACAAGGAACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGTGACTGTGACTCTGATGAGGGGTCTCTGTTC
ACTCTGAGCTCCATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGATGAGGAGTCCCTGCAGGACGAGAGCTCAGGG
GCAAGCAAGGACAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACAATTCCAGGGAAATGCAAGAATCAAGAAGAT
CCCTTTGAAAAACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAAAATGCCTCTGACACTGATAGATCTGAGGGC
CTGTCACCCTGGCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATGTTCACTTATGATTATGACACAGCTCTTCAA
TCCAAGGCAGCAGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTTTTACAGCAAACACCACCATGTTCTGCTGAA
GTTCCCTCAGATCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAAGAATCTTTCATTAAGGAAATATTCACAGCT
CTAAACAATATTCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATCCTGAAGGAGACAACATGAATTCCAACCAAG
TGGACACTGATGCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGGTTATAAGCTAAACACACTTGTTAACATCCT
ATGGGGATGAACCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTCCAAGAACCATGCACCATTATTACAAGAGCT
CCAAACAAAACCAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATATTCAGAAGAGAATCTGTTGCAGTTAGACGA
AGTGGTTCTAACTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCTCTGAAAAGAACAGCTTTAGGATGACAAAGA
CAAGGATGTTCAACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGAAGCACTTAAGTGGAAATGCTGGATAGATTT
TAATGAATTCTGAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAATTGGAAAAGTTCTGAGTAAATATAAATGTT

>112_112_7_AASDH-LRRC66_AASDH_chr4_57217508_ENST00000502617_LRRC66_chr4_52869558_ENST00000343457_length(amino acids)=724AA_BP=9
MGKITVFVEGLWKLKSLQSLDLSFNGILQIGWSDFHNCLQLENLCLKSNKIFKIPPQAFKDLKKLQVIDLSNNALITILPMMIIALEFPH
LVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSRISRETRLPPIHLHRMKSLIRSKAERPQGGRHTGISTLG
KKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFLVAFSLGAFTRPYVDRLWQKKCQSKSPGLDNAYSNEGFY
DDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRSRKDPGSSQSPGQCGDNTGAGSGNDGAVYSILQRHPHAG
NRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGSSRYDSNELDPSLSGEITASLCKMLTHAEAQRTGDSKER
GGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPYGDPRDTGPSVFPPRWDSGLDVTPANKEPVQKSTPSDTC
CELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVTAVDSLEENVTFQTIPGKCKNQEDPFEKPLISAPDSGMY
KTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWHCSLRDLEFSNVDVLQQTPPCSAEVPSDPDKAAFHERDS

--------------------------------------------------------------
>112_112_8_AASDH-LRRC66_AASDH_chr4_57217508_ENST00000513376_LRRC66_chr4_52864103_ENST00000343457_length(transcript)=4178nt_BP=1524nt
CCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGAGACTTGCTAAAATTCTCCAAGTCCCGGCTGCTTATGTA
CCTATCGAGCCAGATTCACCACCGTCATTATCAACTCATTTTATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATT
AATAAATTTAAATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGG
AAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAAT
GAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAG
ATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGGGTACTTTTTGACATCACACAAGAAGATGTTTTGTTTCTG
GCTTCACCTCTGACCTTCGATCCTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCAACTTCCGTC
AAGTTGCTCCCATCAAAATTAGCCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTTAGAAGATTT
GGATCTCAGCTTATCAAGTCAACTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCATCATTGACA
GTTCTCAGAAGCTGGAGAGGAGAAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCGACCATTTAT
AGGATTCCAGAGAAGACTCTTAACTCTACTCTCAAATGTGAATTGCCTGTACAACTGGGATTTCCACTTCTTGGAACAGTAGTTGAAGTC
AGAGATACTAATGGCTTCACAATTCAGGAAGGCAGTGGCCAAGTATTTTTAGGTGGCAGAAACAGAGTGTGTTTTCTTGATGATGAAGTG
ACAGTACCACTTGGCACAATGCGAGCTACAGGAGACTTTGTGACTGTGAAAGATGGAGAGATTTTTTTTTTGGGACGAAAAGACAGTCAG
ATCAAACGTCATGGCAAACGTCTTAACATTGAACTTGTGCAACAGGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCAGTTACATGG
TATAATCAGGAAAAATTAATTCTCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAATATCTTCCA
AGTCATGCAGTCCCGGATGAGCTTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTAAACAAGATA
TATTTAAACTACATAAACTTGAAGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGGAAGGTCATA
GACCTTAGCAACAATGCTCTGATTACCATCCTACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTGGCTGATAAT
AACTGGCAGTGTGATGATAGTGTGGCAGTCTTTCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGCAACAGGTCT
ATAGGGAGTGAGGAGGCCAACGGGGGCACTCCCCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCATCGCATGAAA
AGCCTCATAAGGAGCAAAGCAGAGAGGCCCCAGGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCCGGCTCTGGT
CTCAGGAAGAAGCAGAGACGGCTGCCAAGGAGTGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCTCCCCAGGAC
CTGGCTCTGGCGGTGTGCCTGTCAGTGTTCATCACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTTGACAGACTG
TGGCAAAAAAAGTGCCAGAGCAAAAGCCCTGGCCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCTGCGGGGCAC
ACACCACACCCAGAGACCCATCTGCGCCAAGTATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACACAGCCACAC
CCACACGCCACCGTAATTCCTGATAGAACTCTGGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGCGGGGACAAC
ACCGGGGCAGGAAGTGGAAATGATGGTGCAGTCTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATGTCAGCAGCG
CAGGACCACATCCATAGGAATGATATTCTCGGAGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACATTCAGTGGGC
GTCTCTTCTGTAGCTGGCACGTCTCACGCTGTCTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCCGGAGAAATA
ACAGCTTCCCTCTGTAAAATGCTAACACATGCAGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAGTCACTTTGG
GACTCGCAGATGGAATTTTCTAAGGAAAGGCAAGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCCGGGGCAAGG
GCTGAGGAAGCGCTTTCAGCCCACTACAGCGAGGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCAAGATGGGAC
AGTGGCCTGGATGTCACTCCTGCTAACAAGGAACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGTGACTGTGAC
TCTGATGAGGGGTCTCTGTTCACTCTGAGCTCCATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGATGAGGAGTCC
CTGCAGGACGAGAGCTCAGGGGCAAGCAAGGACAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACAATTCCAGGG
AAATGCAAGAATCAAGAAGATCCCTTTGAAAAACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAAAATGCCTCT
GACACTGATAGATCTGAGGGCCTGTCACCCTGGCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATGTTCACTTAT
GATTATGACACAGCTCTTCAATCCAAGGCAGCAGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTTTTACAGCAA
ACACCACCATGTTCTGCTGAAGTTCCCTCAGATCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAAGAATCTTTC
ATTAAGGAAATATTCACAGCTCTAAACAATATTCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATCCTGAAGGAG
ACAACATGAATTCCAACCAAGTGGACACTGATGCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGGTTATAAGCT
AAACACACTTGTTAACATCCTATGGGGATGAACCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTCCAAGAACCA
TGCACCATTATTACAAGAGCTCCAAACAAAACCAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATATTCAGAAGA
GAATCTGTTGCAGTTAGACGAAGTGGTTCTAACTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCTCTGAAAAGA
ACAGCTTTAGGATGACAAAGACAAGGATGTTCAACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGAAGCACTTAA
GTGGAAATGCTGGATAGATTTTAATGAATTCTGAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAATTGGAAAAG

>112_112_8_AASDH-LRRC66_AASDH_chr4_57217508_ENST00000513376_LRRC66_chr4_52864103_ENST00000343457_length(amino acids)=1122AA_BP=0
MKKCNLKYILVEKKQINKFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKH
CLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSH
HRVTVLQATPTLLRRFGSQLIKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLNSTLKCE
LPVQLGFPLLGTVVEVRDTNGFTIQEGSGQVFLGGRNRVCFLDDEVTVPLGTMRATGDFVTVKDGEIFFLGRKDSQIKRHGKRLNIELVQ
QVAEELQQVESCAVTWYNQEKLILFMVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNYINLKSENKLS
GKEDLWEKLQYLWKVIDLSNNALITILPMMIIALEFPHLVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSR
ISRETRLPPIHLHRMKSLIRSKAERPQGGRHTGISTLGKKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFL
VAFSLGAFTRPYVDRLWQKKCQSKSPGLDNAYSNEGFYDDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRS
RKDPGSSQSPGQCGDNTGAGSGNDGAVYSILQRHPHAGNRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGS
SRYDSNELDPSLSGEITASLCKMLTHAEAQRTGDSKERGGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPY
GDPRDTGPSVFPPRWDSGLDVTPANKEPVQKSTPSDTCCELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVT
AVDSLEENVTFQTIPGKCKNQEDPFEKPLISAPDSGMYKTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWH

--------------------------------------------------------------
>112_112_9_AASDH-LRRC66_AASDH_chr4_57217508_ENST00000602986_LRRC66_chr4_52864103_ENST00000343457_length(transcript)=4367nt_BP=1713nt
ACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGA
GACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGAAATGACTCTTCAGGAATTGGTGCATAAGGCTGCCTCCTG
TTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCCAGTTTACTACACCTACAAGACTGTGGTTAATGCTGCTTC
TGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGAAATTGGTCTCTACTGCCAACCTGGGATAGACTTACCCTC
TTGGATTTTAGGAAATTTAAATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGA
CTTCACTGGAAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAG
CATGTCAATGAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGG
ATACCGAAGATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGGGTACTTTTTGACATCACACAAGAAGATGTT
TTGTTTCTGGCTTCACCTCTGACCTTCGATCCTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCA
ACTTCCGTCAAGTTGCTCCCATCAAAATTAGCCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTT
AGAAGATTTGGATCTCAGCTTATCAAGTCAACTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCA
TCATTGACAGTTCTCAGAAGCTGGAGAGGAGAAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCG
ACCATTTATAGGATTCCAGAGAAGACTCTTAACTCTACTCTCAAATGTGAATTGCCTGTACAACTGGGATTTCCACTTCTTGGAACAGTA
GTTGAAGTCAGAGATACTAATGGCTTCACAATTCAGGAAGGCAGTGGCCAAGTATTTTTAGGTGGCAGAAACAGAGTGTGTTTTCTTGAT
GATGAAGTGACAGTACCACTTGGCACAATGCGAGCTACAGGAGACTTTGTGACTGTGAAAGATGGAGAGATTTTTTTTTTGGGACGAAAA
GACAGTCAGATCAAACGTCATGGCAAACGTCTTAACATTGAACTTGTGCAACAGGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCA
GTTACATGGTATAATCAGGAAAAATTAATTCTCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAA
TATCTTCCAAGTCATGCAGTCCCGGATGAGCTTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTA
AACAAGATATATTTAAACTACATAAACTTGAAGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGG
AAGGTCATAGACCTTAGCAACAATGCTCTGATTACCATCCTACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTG
GCTGATAATAACTGGCAGTGTGATGATAGTGTGGCAGTCTTTCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGC
AACAGGTCTATAGGGAGTGAGGAGGCCAACGGGGGCACTCCCCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCAT
CGCATGAAAAGCCTCATAAGGAGCAAAGCAGAGAGGCCCCAGGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCC
GGCTCTGGTCTCAGGAAGAAGCAGAGACGGCTGCCAAGGAGTGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCT
CCCCAGGACCTGGCTCTGGCGGTGTGCCTGTCAGTGTTCATCACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTT
GACAGACTGTGGCAAAAAAAGTGCCAGAGCAAAAGCCCTGGCCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCT
GCGGGGCACACACCACACCCAGAGACCCATCTGCGCCAAGTATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACA
CAGCCACACCCACACGCCACCGTAATTCCTGATAGAACTCTGGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGC
GGGGACAACACCGGGGCAGGAAGTGGAAATGATGGTGCAGTCTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATG
TCAGCAGCGCAGGACCACATCCATAGGAATGATATTCTCGGAGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACAT
TCAGTGGGCGTCTCTTCTGTAGCTGGCACGTCTCACGCTGTCTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCC
GGAGAAATAACAGCTTCCCTCTGTAAAATGCTAACACATGCAGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAG
TCACTTTGGGACTCGCAGATGGAATTTTCTAAGGAAAGGCAAGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCC
GGGGCAAGGGCTGAGGAAGCGCTTTCAGCCCACTACAGCGAGGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCA
AGATGGGACAGTGGCCTGGATGTCACTCCTGCTAACAAGGAACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGT
GACTGTGACTCTGATGAGGGGTCTCTGTTCACTCTGAGCTCCATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGAT
GAGGAGTCCCTGCAGGACGAGAGCTCAGGGGCAAGCAAGGACAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACA
ATTCCAGGGAAATGCAAGAATCAAGAAGATCCCTTTGAAAAACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAA
AATGCCTCTGACACTGATAGATCTGAGGGCCTGTCACCCTGGCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATG
TTCACTTATGATTATGACACAGCTCTTCAATCCAAGGCAGCAGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTT
TTACAGCAAACACCACCATGTTCTGCTGAAGTTCCCTCAGATCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAA
GAATCTTTCATTAAGGAAATATTCACAGCTCTAAACAATATTCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATC
CTGAAGGAGACAACATGAATTCCAACCAAGTGGACACTGATGCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGG
TTATAAGCTAAACACACTTGTTAACATCCTATGGGGATGAACCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTC
CAAGAACCATGCACCATTATTACAAGAGCTCCAAACAAAACCAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATA
TTCAGAAGAGAATCTGTTGCAGTTAGACGAAGTGGTTCTAACTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCT
CTGAAAAGAACAGCTTTAGGATGACAAAGACAAGGATGTTCAACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGA
AGCACTTAAGTGGAAATGCTGGATAGATTTTAATGAATTCTGAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAA

>112_112_9_AASDH-LRRC66_AASDH_chr4_57217508_ENST00000602986_LRRC66_chr4_52864103_ENST00000343457_length(amino acids)=1118AA_BP=1
MPTWDRLTLLDFRKFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKHCLAY
VLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVT
VLQATPTLLRRFGSQLIKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLNSTLKCELPVQ
LGFPLLGTVVEVRDTNGFTIQEGSGQVFLGGRNRVCFLDDEVTVPLGTMRATGDFVTVKDGEIFFLGRKDSQIKRHGKRLNIELVQQVAE
ELQQVESCAVTWYNQEKLILFMVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNYINLKSENKLSGKED
LWEKLQYLWKVIDLSNNALITILPMMIIALEFPHLVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSRISRE
TRLPPIHLHRMKSLIRSKAERPQGGRHTGISTLGKKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFLVAFS
LGAFTRPYVDRLWQKKCQSKSPGLDNAYSNEGFYDDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRSRKDP
GSSQSPGQCGDNTGAGSGNDGAVYSILQRHPHAGNRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGSSRYD
SNELDPSLSGEITASLCKMLTHAEAQRTGDSKERGGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPYGDPR
DTGPSVFPPRWDSGLDVTPANKEPVQKSTPSDTCCELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVTAVDS
LEENVTFQTIPGKCKNQEDPFEKPLISAPDSGMYKTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWHCSLR

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for AASDH-LRRC66

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for AASDH-LRRC66

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for AASDH-LRRC66

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source

Fusion Gene Studies in Kim Lab

Fusion gene:AASDH-LRRC66 (FusionGDB2 ID:HG132949TG339977)

Fusion Gene Summary for AASDH-LRRC66

Fusion Gene ORF analysis for AASDH-LRRC66

Fusion Genomic Features for AASDH-LRRC66

Fusion Protein Features for AASDH-LRRC66

Fusion Gene Sequence for AASDH-LRRC66

Fusion Gene PPI Analysis for AASDH-LRRC66

Related Drugs for AASDH-LRRC66

Related Diseases for AASDH-LRRC66

Fusion Gene Studies
in Kim Lab