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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:CPT1A-MAPK8IP3 (FusionGDB2 ID:HG1374TG23162)

Fusion Gene Summary for CPT1A-MAPK8IP3

Fusion gene summary

Fusion gene information	Fusion gene name: CPT1A-MAPK8IP3
	Fusion gene ID: hg1374tg23162
		Hgene	Tgene
	Gene symbol	CPT1A	MAPK8IP3
	Gene ID	1374	23162
	Gene name	carnitine palmitoyltransferase 1A	mitogen-activated protein kinase 8 interacting protein 3
	Synonyms	CPT1\|CPT1-L\|L-CPT1	JIP-3\|JIP3\|JSAP1\|NEDBA\|SYD2\|syd
	Cytomap	('CPT1A')('MAPK8IP3') 11q13.3	16p13.3
	Type of gene	protein-coding	protein-coding
	Description	carnitine O-palmitoyltransferase 1, liver isoformCPT ICPTI-Lcarnitine O-palmitoyltransferase I, liver isoformcarnitine palmitoyltransferase 1A (liver)carnitine palmitoyltransferase I, liver	C-Jun-amino-terminal kinase-interacting protein 3C-jun-amino-terminal kinase interacting protein 3JNK MAP kinase scaffold protein 3JNK-interacting protein 3JNK/SAPK-associated protein-1JNK/stress-activated protein kinase-associated protein 1homolog
	Modification date	20200315	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000265641, ENST00000376618, ENST00000539743, ENST00000540367, ENST00000537756, ENST00000538994,
Fusion gene scores	* DoF score	25 X 23 X 12=6900	8 X 8 X 6=384
	# samples	32	9
	** MAII score	log2(32/6900*10)=-4.43045255166553 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(9/384*10)=-2.09310940439148 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: CPT1A [Title/Abstract] AND MAPK8IP3 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	CPT1A(68579905)-MAPK8IP3(1779139), # samples:1
Anticipated loss of major functional domain due to fusion event.	CPT1A-MAPK8IP3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CPT1A-MAPK8IP3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CPT1A-MAPK8IP3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CPT1A-MAPK8IP3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CPT1A-MAPK8IP3 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF. CPT1A-MAPK8IP3 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	CPT1A	GO:0001676	long-chain fatty acid metabolic process	11350182
Hgene	CPT1A	GO:0009437	carnitine metabolic process	11350182

Fusion gene breakpoints across CPT1A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across MAPK8IP3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	PAAD	TCGA-OE-A75W-01A	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+

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Fusion Gene ORF analysis for CPT1A-MAPK8IP3

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000265641	ENST00000568271	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+
5CDS-intron	ENST00000376618	ENST00000568271	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+
5CDS-intron	ENST00000539743	ENST00000568271	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+
5CDS-intron	ENST00000540367	ENST00000568271	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+
Frame-shift	ENST00000539743	ENST00000250894	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+
Frame-shift	ENST00000539743	ENST00000356010	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+
Frame-shift	ENST00000540367	ENST00000250894	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+
Frame-shift	ENST00000540367	ENST00000356010	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+
In-frame	ENST00000265641	ENST00000250894	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+
In-frame	ENST00000265641	ENST00000356010	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+
In-frame	ENST00000376618	ENST00000250894	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+
In-frame	ENST00000376618	ENST00000356010	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+
intron-3CDS	ENST00000537756	ENST00000250894	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+
intron-3CDS	ENST00000537756	ENST00000356010	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+
intron-3CDS	ENST00000538994	ENST00000250894	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+
intron-3CDS	ENST00000538994	ENST00000356010	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+
intron-intron	ENST00000537756	ENST00000568271	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+
intron-intron	ENST00000538994	ENST00000568271	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000376618	CPT1A	chr11	68579905	-	ENST00000250894	MAPK8IP3	chr16	1779139	+	5516	451	420	4022	1200
ENST00000376618	CPT1A	chr11	68579905	-	ENST00000356010	MAPK8IP3	chr16	1779139	+	4321	451	420	4004	1194
ENST00000265641	CPT1A	chr11	68579905	-	ENST00000250894	MAPK8IP3	chr16	1779139	+	5501	436	405	4007	1200
ENST00000265641	CPT1A	chr11	68579905	-	ENST00000356010	MAPK8IP3	chr16	1779139	+	4306	436	405	3989	1194

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000376618	ENST00000250894	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+	0.008507979	0.991492
ENST00000376618	ENST00000356010	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+	0.009237245	0.99076277
ENST00000265641	ENST00000250894	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+	0.008336654	0.99166334
ENST00000265641	ENST00000356010	CPT1A	chr11	68579905	-	MAPK8IP3	chr16	1779139	+	0.009017314	0.9909827

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Fusion Genomic Features for CPT1A-MAPK8IP3

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
CPT1A	chr11	68579904	-	MAPK8IP3	chr16	1779138	+	6.35E-06	0.9999937
CPT1A	chr11	68579904	-	MAPK8IP3	chr16	1779138	+	6.35E-06	0.9999937

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CPT1A-MAPK8IP3

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:68579905/chr16:1779139)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000265641

2_47

774.0

Topological domain

Cytoplasmic

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000376618

2_47

757.0

Topological domain

Cytoplasmic

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000539743

2_47

774.0

Topological domain

Cytoplasmic

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000540367

2_47

757.0

Topological domain

Cytoplasmic

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000265641

48_73

774.0

Transmembrane

Helical

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000376618

48_73

757.0

Transmembrane

Helical

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000539743

48_73

774.0

Transmembrane

Helical

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000540367

48_73

757.0

Transmembrane

Helical

Tgene

MAPK8IP3

chr11:68579905

chr16:1779139

ENST00000250894

440_554

146

1337.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

MAPK8IP3

chr11:68579905

chr16:1779139

ENST00000250894

520_594

146

1337.0

Domain

RH2

Tgene

MAPK8IP3

chr11:68579905

chr16:1779139

ENST00000250894

209_225

146

1337.0

Region

JNK-binding domain (JBD)%3B essential for its function in axon elongation

Tgene

MAPK8IP3

chr11:68579905

chr16:1779139

ENST00000250894

423_458

146

1337.0

Region

Leucine zipper-like domain (LZ)%3B essential for its function in axon elongation

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000265641

555_567

774.0

Region

Coenzyme A binding

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000376618

555_567

757.0

Region

Coenzyme A binding

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000539743

555_567

774.0

Region

Coenzyme A binding

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000540367

555_567

757.0

Region

Coenzyme A binding

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000265641

123_773

774.0

Topological domain

Cytoplasmic

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000265641

74_102

774.0

Topological domain

Mitochondrial intermembrane

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000376618

123_773

757.0

Topological domain

Cytoplasmic

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000376618

74_102

757.0

Topological domain

Mitochondrial intermembrane

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000539743

123_773

774.0

Topological domain

Cytoplasmic

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000539743

74_102

774.0

Topological domain

Mitochondrial intermembrane

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000540367

123_773

757.0

Topological domain

Cytoplasmic

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000540367

74_102

757.0

Topological domain

Mitochondrial intermembrane

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000265641

103_122

774.0

Transmembrane

Helical

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000376618

103_122

757.0

Transmembrane

Helical

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000539743

103_122

774.0

Transmembrane

Helical

Hgene

CPT1A

chr11:68579905

chr16:1779139

ENST00000540367

103_122

757.0

Transmembrane

Helical

Tgene

MAPK8IP3

chr11:68579905

chr16:1779139

ENST00000250894

58_177

146

1337.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

MAPK8IP3

chr11:68579905

chr16:1779139

ENST00000250894

12_100

146

1337.0

Domain

RH1

Tgene

MAPK8IP3

chr11:68579905

chr16:1779139

ENST00000250894

50_80

146

1337.0

Region

Kinesin-binding domain (KBD)%3B essential for its function in axon elongation

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Fusion Gene Sequence for CPT1A-MAPK8IP3

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>19223_19223_1_CPT1A-MAPK8IP3_CPT1A_chr11_68579905_ENST00000265641_MAPK8IP3_chr16_1779139_ENST00000250894_length(transcript)=5501nt_BP=436nt
AATCCGCTGCTGCCGGCGTCGGGTGCGCTCGGCCTCGCCCGCGGCCCTCCTTCCCCGGCTCCCGCTCGCCGCTCGTTCACTCCACCGCCG
CCGCCGCCGCCGCCGCTGCCGCTGCCGCTGCCGCACCTCCGTAGCTGACTCGGTACTCTCTGAAGATGGCAGAAGCTCACCAAGCTGTGG
CCTTTCAGTTCACGGTCACTCCGGACGGGATTGACCTGCGGCTGAGCCATGAAGCTCTTAGACAAATCTATCTCTCTGGACTTCATTCCT
GGAAAAAGAAGTTCATCAGATTCAAGAACGGCATCATCACTGGCGTGTACCCGGCAAGCCCCTCCAGTTGGCTTATCGTGGTGGTGGGCG
TGATGACAACGATGTACGCCAAGATCGACCCCTCGTTAGGAATAATTGCAAAAATCAATCGGACTCTGGAAACGGCTTTCCCGGTTGGAG
GAGCGGGAGTCGGAGATGAAGAAGGAGTACAATGCCCTGCACCAGCGGCACACAGAGATGATACAGACCTACGTGGAGCACATTGAGAGG
TCCAAGATGCAGCAGGTCGGAGGAAACAGCCAGACCGAGAGCAGCCTGCCGGGGCGGAGGAAGGAGCGCCCCACCTCCCTGAACGTGTTC
CCCCTGGCTGACGGCACGGTACGTGCACAGATCGGGGGCAAGCTCGTGCCTGCGGGGGACCACTGGCACCTGAGTGACCTCGGCCAGCTG
CAGTCCAGCTCCAGCTACCAGTGTCCACAGGATGAAATGTCCGAGTCAGGCCAGTCCTCGGCGGCCGCCACACCCAGCACCACAGGCACC
AAGTCCAACACGCCCACATCCTCCGTGCCCTCGGCCGCCGTCACACCCCTCAACGAGAGCCTGCAGCCCCTGGGGGACTATGGCGTGGGC
TCCAAGAACAGCAAGCGTGCCCGGGAGAAGCGCGACAGCCGCAACATGGAAGTACAGGTCACCCAGGAGATGCGCAACGTCAGTATAGGC
ATGGGCAGCAGTGACGAGTGGTCTGATGTTCAAGACATTATTGACTCCACGCCAGAGCTGGACATGTGTCCAGAGACCCGCCTGGACCGC
ACAGGAAGCAGCCCAACCCAGGGCATCGTGAACAAAGCTTTCGGCATCAACACCGACTCCCTGTACCATGAGCTGTCGACGGCAGGGTCT
GAGGTCATCGGGGATGTGGACGAAGGGGCCGACCTCCTAGGGGAGTTCTCAGTGCGCGATGATTTCTTTGGAATGGGCAAAGAAGTGGGG
AATCTGCTACTGGAAAACTCACAGCTTCTGGAAACCAAAAACGCCTTGAATGTGGTGAAGAATGACCTGATTGCCAAGGTCGACCAGCTG
TCCGGGGAGCAGGAGGTGCTGAGGGGCGAGTTGGAGGCTGCTAAGCAGGCCAAAGTCAAGCTGGAAAACCGTATCAAGGAGCTGGAAGAG
GAACTGAAAAGAGTGAAGTCCGAGGCCATCATCGCCCGCCGTGAACCCAAAGAAGAGGCGGAGGATGTAAGCAGCTATCTCTGTACAGAA
TCGGACAAAATCCCCATGGCCCAGCGCCGCCGCTTCACGCGGGTGGAGATGGCCCGTGTGCTCATGGAGCGGAACCAGTACAAGGAGCGG
CTGATGGAGCTGCAGGAGGCTGTGCGGTGGACTGAGATGATCAGAGCGTCCCGAGAGCACCCATCCGTCCAGGAGAAGAAGAAGTCGACC
ATCTGGCAGTTCTTCAGCCGCCTCTTCAGCTCTTCCTCCAGCCCCCCTCCGGCCAAGCGCCCCTATCCCTCGGTGAACATCCACTACAAG
TCACCCACCACTGCCGGCTTCAGCCAGCGCCGCAACCATGCCATGTGCCCGATCTCGGCAGGCAGCCGGCCCCTGGAATTCTTCCCTGAC
GACGACTGCACGTCCTCCGCCCGTCGAGAGCAGAAGCGCGAGCAGTACCGCCAGGTGCGTGAGCACGTGCGTAACGACGACGGCCGTCTG
CAGGCCTGCGGCTGGAGCCTGCCCGCCAAGTACAAGCAGCTGAGTCCCAACGGGGGCCAGGAGGACACGCGGATGAAGAACGTGCCGGTG
CCGGTGTACTGCCGCCCTCTGGTGGAGAAGGACCCCACCATGAAGCTGTGGTGTGCCGCGGGCGTCAACCTGAGCGGGTGGAGGCCCAAT
GAGGACGACGCTGGGAATGGAGTCAAGCCAGCGCCAGGCCGCGATCCCCTGACCTGCGACCGCGAAGGAGACGGCGAGCCCAAGAGCGCC
CACACGTCTCCCGAGAAGAAGAAGGCCAAGGAGCTCCCTGAAATGGACGCCACCTCCAGCCGGGTGTGGATCCTGACCAGCACCCTGACC
ACCAGCAAGGTGGTGATCATCGACGCCAACCAGCCGGGCACGGTGGTGGACCAGTTCACCGTCTGCAACGCGCACGTGCTGTGCATCTCC
AGCATCCCCGCGGCCAGCGACAGCGACTACCCTCCCGGGGAGATGTTCCTGGACAGCGACGTGAACCCAGAGGACCCGGGCGCAGATGGC
GTGCTGGCCGGTATCACCCTGGTGGGCTGTGCCACCCGCTGCAACGTGCCGCGGAGCAACTGCTCCTCCCGAGGGGACACCCCAGTGCTA
GACAAGGGGCAGGGGGAGGTGGCCACCATCGCCAACGGGAAGGTCAACCCGTCCCAGTCCACAGAGGAGGCCACAGAGGCCACGGAGGTG
CCAGACCCTGGGCCCAGCGAGCCAGAGACAGCCACATTGCGGCCCGGGCCTCTCACAGAGCACGTCTTCACTGACCCAGCCCCGACCCCG
TCCTCTGGCCCCCAGCCTGGCAGCGAGAACGGGCCAGAGCCTGACAGCAGCAGCACACGGCCAGAGCCAGAGCCCAGCGGGGACCCCACG
GGAGCAGGCAGCAGTGCTGCACCCACCATGTGGCTGGGAGCCCAGAACGGCTGGCTCTATGTGCACTCGGCTGTGGCCAACTGGAAGAAG
TGCCTGCACTCCATCAAGCTGAAGGATTCTGTGCTGAGCCTGGTGCATGTCAAAGGCCGTGTGCTGGTGGCTCTGGCGGACGGGACCCTG
GCCATCTTCCACCGTGGTGAAGATGGCCAGTGGGATCTGAGCAACTATCACCTAATGGACCTGGGCCACCCGCACCACTCCATCCGCTGC
ATGGCTGTTGTGTACGACCGCGTGTGGTGTGGCTACAAGAACAAGGTGCACGTCATCCAGCCCAAGACCATGCAGATAGAGAAGTCATTT
GACGCCCACCCGCGGCGGGAGAGCCAGGTGCGGCAGCTGGCGTGGATCGGCGATGGCGTATGGGTGTCCATCCGCCTGGACTCCACCCTG
AGGCTCTACCATGCACACACGCACCAGCATCTACAGGACGTGGACATTGAGCCCTACGTCAGCAAGATGCTAGGCACTGGCAAGCTGGGT
TTCTCCTTCGTACGCATCACGGCCCTGCTTGTCGCGGGCAGCCGGCTCTGGGTGGGCACCGGCAACGGAGTGGTCATCTCCATCCCCCTG
ACAGAGACTGTGGTCCTGCACCGAGGCCAGCTCCTGGGGCTCCGAGCCAATAAGACATCCCCCACCTCTGGGGAGGGCGCCCGTCCCGGG
GGCATCATCCACGTGTATGGCGATGACAGCAGTGACAGGGCGGCCAGCAGCTTCATCCCCTACTGCTCCATGGCCCAGGCCCAGCTATGC
TTCCATGGGCACCGCGATGCCGTGAAGTTCTTTGTCTCGGTGCCAGGGAACGTGCTGGCCACCCTGAATGGGAGTGTGCTGGACAGCCCA
GCCGAGGGCCCTGGGCCAGCTGCCCCTGCCTCGGAGGTCGAGGGCCAGAAGCTGCGGAACGTGCTGGTGCTGAGCGGCGGGGAGGGCTAC
ATCGACTTCCGCATTGGAGACGGAGAGGACGACGAGACGGAGGAGGGCGCAGGGGACATGAGCCAGGTGAAGCCCGTGCTGTCCAAGGCA
GAGCGCAGTCACATCATCGTGTGGCAGGTGTCCTACACCCCCGAGTGAAGCTGCTGCCCTGCCTGGCCCGACCTGTACATAGGACCCCCG
ACCACCTGACCCCCGCCCGGCCCGCGGGGTAGCCAGCCAGGCGCCGCCGCCCCTCTTCTAACCTCTCAACCTGCAGCTTTCACCTGAGTC
TGGCCCCTCCAGCGGGCAGGGAGTGCGGGGATGCGGATCAGCTGGGAGGAGGAGGGGAGGGGAACTTCCACCCGAGGGGAAGATGCTCTC
GGGACAGTTTCCCGGGCAGCTCCTGGCCAGCTTCCAGCCCAGAGTCCTCAAGTCCAGGGCACCTTGGGCCCAGCGCAGGCAGAATCCGAG
GTGGTCCTGGCTCTACCCTGGGCCTCCTACTCCCCAGCACCCCTGGAGGAGGCAGGGGCTCCCCGCCGCCGAGGCTGCCTGCCCTGGGCC
CACCTCTGCATGCTGCTCATGGGGCCACCCTGCCTCCTGGGCCCTCACTCTGCCTAGGGGAGCTGGGCCAGGCACTAGCCTTTGCCCAGG
GAGGTGGGCCTCAGGCTGCCCAGGTGCCTGCACCCCAGCCGGCCTTCTCTGGGGCCTCCCCGTCGTCAAGCCTCTATCCTGTCTGTCCCC
ACCCCAGCTGTCCCCTGCCCAGGGAGCTGGCATAAAAGCACGAGGCCCGGCTCCCTGGGGCAGCTGCTTGAGAACAGAGACTGCTACCCC
ATCCTGCCCATGCAGGCAGGCTCTTGCCAGCCCCGTTCTGACCCGTGTCCCCCCAGGCTCTGCCTGGGCAGAAGACTCACCTTGGAGGAG
TGGGCCCTGGAGTCCTGTCCCTCCCAGAAGCCCCCAGGGTGGGATTTCTCAGGCTGCCAGGGCAGGCCCAGGCCTCAGGAAGAAGGGGAG
GCCCCTGGCCTCTCCGGGATCAGTCCTAGGACACAGGCTCAGCCTCAGGTTGATGGGGGATGATGTGCTCCCGGGGCCTGCCTCCTGCAC
GGGGCTCCACGGAGCCCAGCTCCCAGACACGCTACTAAGTGCCTAGGGTTGCCCGCTGTGGCCTGCTTCCAGGGAGCAACAGAGAGGCCA
CCAAGCAGAGGCCCGTGGGGCTGAGGATGGAGCCGCCCCCAGCCGACTCCAAGCCCGCAGAGGGCAGACGCCACCCTGGACTGCTCTCCC
TGCCCAGCTGGGCCTCTCTGGCCTATTCCTACCTTCCAGGCCCACTGCACTCCTGTCTGGGAGGCCCTTATGAGGGCAGCCCAGCCCCCG
CACCCACCCCCAACCAGAGAAGCACAGATCTTGGGGAGCTGCCCCACAAGCCCCGCTGGCCACCGAGGGCTGCAGCCGCTGCGCTGCCGG
CTTCTCCCCACCACCCTGCCACCTCCACTGTGATGTATGTCCGCTCCCTCGTCTGTTCCCCCAGGATCTCGAAGTGACTCCGGGCTGAGC
AGTGGGGCGGCTGGGGGAGGGGTGACGATTCTCCTCAGGCTTTGGCCCTGCAAGCAAACCCACATATCTGCTCTGTATGTAATAAATGTC
TTAACGTCGTA

>19223_19223_1_CPT1A-MAPK8IP3_CPT1A_chr11_68579905_ENST00000265641_MAPK8IP3_chr16_1779139_ENST00000250894_length(amino acids)=1200AA_BP=11
MQKSIGLWKRLSRLEERESEMKKEYNALHQRHTEMIQTYVEHIERSKMQQVGGNSQTESSLPGRRKERPTSLNVFPLADGTVRAQIGGKL
VPAGDHWHLSDLGQLQSSSSYQCPQDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQPLGDYGVGSKNSKRAREKRDSRN
MEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDMCPETRLDRTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGE
FSVRDDFFGMGKEVGNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLRGELEAAKQAKVKLENRIKELEEELKRVKSEAIIARRE
PKEEAEDVSSYLCTESDKIPMAQRRRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASREHPSVQEKKKSTIWQFFSRLFSSSSSP
PPAKRPYPSVNIHYKSPTTAGFSQRRNHAMCPISAGSRPLEFFPDDDCTSSARREQKREQYRQVREHVRNDDGRLQACGWSLPAKYKQLS
PNGGQEDTRMKNVPVPVYCRPLVEKDPTMKLWCAAGVNLSGWRPNEDDAGNGVKPAPGRDPLTCDREGDGEPKSAHTSPEKKKAKELPEM
DATSSRVWILTSTLTTSKVVIIDANQPGTVVDQFTVCNAHVLCISSIPAASDSDYPPGEMFLDSDVNPEDPGADGVLAGITLVGCATRCN
VPRSNCSSRGDTPVLDKGQGEVATIANGKVNPSQSTEEATEATEVPDPGPSEPETATLRPGPLTEHVFTDPAPTPSSGPQPGSENGPEPD
SSSTRPEPEPSGDPTGAGSSAAPTMWLGAQNGWLYVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGEDGQWDLSN
YHLMDLGHPHHSIRCMAVVYDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVD
IEPYVSKMLGTGKLGFSFVRITALLVAGSRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKTSPTSGEGARPGGIIHVYGDDSSDRAA
SSFIPYCSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDSPAEGPGPAAPASEVEGQKLRNVLVLSGGEGYIDFRIGDGEDDETEE
GAGDMSQVKPVLSKAERSHIIVWQVSYTPE

--------------------------------------------------------------
>19223_19223_2_CPT1A-MAPK8IP3_CPT1A_chr11_68579905_ENST00000265641_MAPK8IP3_chr16_1779139_ENST00000356010_length(transcript)=4306nt_BP=436nt
AATCCGCTGCTGCCGGCGTCGGGTGCGCTCGGCCTCGCCCGCGGCCCTCCTTCCCCGGCTCCCGCTCGCCGCTCGTTCACTCCACCGCCG
CCGCCGCCGCCGCCGCTGCCGCTGCCGCTGCCGCACCTCCGTAGCTGACTCGGTACTCTCTGAAGATGGCAGAAGCTCACCAAGCTGTGG
CCTTTCAGTTCACGGTCACTCCGGACGGGATTGACCTGCGGCTGAGCCATGAAGCTCTTAGACAAATCTATCTCTCTGGACTTCATTCCT
GGAAAAAGAAGTTCATCAGATTCAAGAACGGCATCATCACTGGCGTGTACCCGGCAAGCCCCTCCAGTTGGCTTATCGTGGTGGTGGGCG
TGATGACAACGATGTACGCCAAGATCGACCCCTCGTTAGGAATAATTGCAAAAATCAATCGGACTCTGGAAACGGCTTTCCCGGTTGGAG
GAGCGGGAGTCGGAGATGAAGAAGGAGTACAATGCCCTGCACCAGCGGCACACAGAGATGATACAGACCTACGTGGAGCACATTGAGAGG
TCCAAGATGCAGCAGGTCGGAGGAAACAGCCAGACCGAGAGCAGCCTGCCGGGGCGGAGGAAGGAGCGCCCCACCTCCCTGAACGTGTTC
CCCCTGGCTGACGGCACGGTACGTGCACAGATCGGGGGCAAGCTCGTGCCTGCGGGGGACCACTGGCACCTGAGTGACCTCGGCCAGCTG
CAGTCCAGCTCCAGCTACCAGTGTCCACAGGATGAAATGTCCGAGTCAGGCCAGTCCTCGGCGGCCGCCACACCCAGCACCACAGGCACC
AAGTCCAACACGCCCACATCCTCCGTGCCCTCGGCCGCCGTCACACCCCTCAACGAGAGCCTGCAGCCCCTGGGGGACTATGGCGTGGGC
TCCAAGAACAGCAAGCGTGCCCGGGAGAAGCGCGACAGCCGCAACATGGAAGTACAGGTCACCCAGGAGATGCGCAACGTCAGTATAGGC
ATGGGCAGCAGTGACGAGTGGTCTGATGTTCAAGACATTATTGACTCCACGCCAGAGCTGGACATGTGTCCAGAGACCCGCCTGGACCGC
ACAGGAAGCAGCCCAACCCAGGGCATCGTGAACAAAGCTTTCGGCATCAACACCGACTCCCTGTACCATGAGCTGTCGACGGCAGGGTCT
GAGGTCATCGGGGATGTGGACGAAGGGGCCGACCTCCTAGGGGAGTTCTCAGGAATGGGCAAAGAAGTGGGGAATCTGCTACTGGAAAAC
TCACAGCTTCTGGAAACCAAAAACGCCTTGAATGTGGTGAAGAATGACCTGATTGCCAAGGTCGACCAGCTGTCCGGGGAGCAGGAGGTG
CTGAGGGGCGAGTTGGAGGCTGCTAAGCAGGCCAAAGTCAAGCTGGAAAACCGTATCAAGGAGCTGGAAGAGGAACTGAAAAGAGTGAAG
TCCGAGGCCATCATCGCCCGCCGTGAACCCAAAGAAGAGGCGGAGGATGTAAGCAGCTATCTCTGTACAGAATCGGACAAAATCCCCATG
GCCCAGCGCCGCCGCTTCACGCGGGTGGAGATGGCCCGTGTGCTCATGGAGCGGAACCAGTACAAGGAGCGGCTGATGGAGCTGCAGGAG
GCTGTGCGGTGGACTGAGATGATCAGAGCGTCCCGAGAGCACCCATCCGTCCAGGAGAAGAAGAAGTCGACCATCTGGCAGTTCTTCAGC
CGCCTCTTCAGCTCTTCCTCCAGCCCCCCTCCGGCCAAGCGCCCCTATCCCTCGGTGAACATCCACTACAAGTCACCCACCACTGCCGGC
TTCAGCCAGCGCCGCAACCATGCCATGTGCCCGATCTCGGCAGGCAGCCGGCCCCTGGAATTCTTCCCTGACGACGACTGCACGTCCTCC
GCCCGTCGAGAGCAGAAGCGCGAGCAGTACCGCCAGGTGCGTGAGCACGTGCGTAACGACGACGGCCGTCTGCAGGCCTGCGGCTGGAGC
CTGCCCGCCAAGTACAAGCAGCTGAGTCCCAACGGGGGCCAGGAGGACACGCGGATGAAGAACGTGCCGGTGCCGGTGTACTGCCGCCCT
CTGGTGGAGAAGGACCCCACCATGAAGCTGTGGTGTGCCGCGGGCGTCAACCTGAGCGGGTGGAGGCCCAATGAGGACGACGCTGGGAAT
GGAGTCAAGCCAGCGCCAGGCCGCGATCCCCTGACCTGCGACCGCGAAGGAGACGGCGAGCCCAAGAGCGCCCACACGTCTCCCGAGAAG
AAGAAGGCCAAGGAGCTCCCTGAAATGGACGCCACCTCCAGCCGGGTGTGGATCCTGACCAGCACCCTGACCACCAGCAAGGTGGTGATC
ATCGACGCCAACCAGCCGGGCACGGTGGTGGACCAGTTCACCGTCTGCAACGCGCACGTGCTGTGCATCTCCAGCATCCCCGCGGCCAGC
GACAGCGACTACCCTCCCGGGGAGATGTTCCTGGACAGCGACGTGAACCCAGAGGACCCGGGCGCAGATGGCGTGCTGGCCGGTATCACC
CTGGTGGGCTGTGCCACCCGCTGCAACGTGCCGCGGAGCAACTGCTCCTCCCGAGGGGACACCCCAGTGCTAGACAAGGGGCAGGGGGAG
GTGGCCACCATCGCCAACGGGAAGGTCAACCCGTCCCAGTCCACAGAGGAGGCCACAGAGGCCACGGAGGTGCCAGACCCTGGGCCCAGC
GAGCCAGAGACAGCCACATTGCGGCCCGGGCCTCTCACAGAGCACGTCTTCACTGACCCAGCCCCGACCCCGTCCTCTGGCCCCCAGCCT
GGCAGCGAGAACGGGCCAGAGCCTGACAGCAGCAGCACACGGCCAGAGCCAGAGCCCAGCGGGGACCCCACGGGAGCAGGCAGCAGTGCT
GCACCCACCATGTGGCTGGGAGCCCAGAACGGCTGGCTCTATGTGCACTCGGCTGTGGCCAACTGGAAGAAGTGCCTGCACTCCATCAAG
CTGAAGGATTCTGTGCTGAGCCTGGTGCATGTCAAAGGCCGTGTGCTGGTGGCTCTGGCGGACGGGACCCTGGCCATCTTCCACCGTGGT
GAAGATGGCCAGTGGGATCTGAGCAACTATCACCTAATGGACCTGGGCCACCCGCACCACTCCATCCGCTGCATGGCTGTTGTGTACGAC
CGCGTGTGGTGTGGCTACAAGAACAAGGTGCACGTCATCCAGCCCAAGACCATGCAGATAGAGAAGTCATTTGACGCCCACCCGCGGCGG
GAGAGCCAGGTGCGGCAGCTGGCGTGGATCGGCGATGGCGTATGGGTGTCCATCCGCCTGGACTCCACCCTGAGGCTCTACCATGCACAC
ACGCACCAGCATCTACAGGACGTGGACATTGAGCCCTACGTCAGCAAGATGCTAGGCACTGGCAAGCTGGGTTTCTCCTTCGTACGCATC
ACGGCCCTGCTTGTCGCGGGCAGCCGGCTCTGGGTGGGCACCGGCAACGGAGTGGTCATCTCCATCCCCCTGACAGAGACTGTGGTCCTG
CACCGAGGCCAGCTCCTGGGGCTCCGAGCCAATAAGACATCCCCCACCTCTGGGGAGGGCGCCCGTCCCGGGGGCATCATCCACGTGTAT
GGCGATGACAGCAGTGACAGGGCGGCCAGCAGCTTCATCCCCTACTGCTCCATGGCCCAGGCCCAGCTATGCTTCCATGGGCACCGCGAT
GCCGTGAAGTTCTTTGTCTCGGTGCCAGGGAACGTGCTGGCCACCCTGAATGGGAGTGTGCTGGACAGCCCAGCCGAGGGCCCTGGGCCA
GCTGCCCCTGCCTCGGAGGTCGAGGGCCAGAAGCTGCGGAACGTGCTGGTGCTGAGCGGCGGGGAGGGCTACATCGACTTCCGCATTGGA
GACGGAGAGGACGACGAGACGGAGGAGGGCGCAGGGGACATGAGCCAGGTGAAGCCCGTGCTGTCCAAGGCAGAGCGCAGTCACATCATC
GTGTGGCAGGTGTCCTACACCCCCGAGTGAAGCTGCTGCCCTGCCTGGCCCGACCTGTACATAGGACCCCCGACCACCTGACCCCCGCCC
GGCCCGCGGGGTAGCCAGCCAGGCGCCGCCGCCCCTCTTCTAACCTCTCAACCTGCAGCTTTCACCTGAGTCTGGCCCCTCCAGCGGGCA
GGGAGTGCGGGGATGCGGATCAGCTGGGAGGAGGAGGGGAGGGGAACTTCCACCCGAGGGGAAGATGCTCTCGGGACAGTTTCCCGGGCA
GCTCCTGGCCAGCTTCCAGCCCAGAGTCCTCAAGTCCAGGGCACCTTGGGCCCAGCGCAGGCAGAATCCGAGGTGG

>19223_19223_2_CPT1A-MAPK8IP3_CPT1A_chr11_68579905_ENST00000265641_MAPK8IP3_chr16_1779139_ENST00000356010_length(amino acids)=1194AA_BP=11
MQKSIGLWKRLSRLEERESEMKKEYNALHQRHTEMIQTYVEHIERSKMQQVGGNSQTESSLPGRRKERPTSLNVFPLADGTVRAQIGGKL
VPAGDHWHLSDLGQLQSSSSYQCPQDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQPLGDYGVGSKNSKRAREKRDSRN
MEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDMCPETRLDRTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGE
FSGMGKEVGNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLRGELEAAKQAKVKLENRIKELEEELKRVKSEAIIARREPKEEAE
DVSSYLCTESDKIPMAQRRRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASREHPSVQEKKKSTIWQFFSRLFSSSSSPPPAKRP
YPSVNIHYKSPTTAGFSQRRNHAMCPISAGSRPLEFFPDDDCTSSARREQKREQYRQVREHVRNDDGRLQACGWSLPAKYKQLSPNGGQE
DTRMKNVPVPVYCRPLVEKDPTMKLWCAAGVNLSGWRPNEDDAGNGVKPAPGRDPLTCDREGDGEPKSAHTSPEKKKAKELPEMDATSSR
VWILTSTLTTSKVVIIDANQPGTVVDQFTVCNAHVLCISSIPAASDSDYPPGEMFLDSDVNPEDPGADGVLAGITLVGCATRCNVPRSNC
SSRGDTPVLDKGQGEVATIANGKVNPSQSTEEATEATEVPDPGPSEPETATLRPGPLTEHVFTDPAPTPSSGPQPGSENGPEPDSSSTRP
EPEPSGDPTGAGSSAAPTMWLGAQNGWLYVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGEDGQWDLSNYHLMDL
GHPHHSIRCMAVVYDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVS
KMLGTGKLGFSFVRITALLVAGSRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKTSPTSGEGARPGGIIHVYGDDSSDRAASSFIPY
CSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDSPAEGPGPAAPASEVEGQKLRNVLVLSGGEGYIDFRIGDGEDDETEEGAGDMS
QVKPVLSKAERSHIIVWQVSYTPE

--------------------------------------------------------------
>19223_19223_3_CPT1A-MAPK8IP3_CPT1A_chr11_68579905_ENST00000376618_MAPK8IP3_chr16_1779139_ENST00000250894_length(transcript)=5516nt_BP=451nt
GGACCCGCCTCAGCCAATCCGCTGCTGCCGGCGTCGGGTGCGCTCGGCCTCGCCCGCGGCCCTCCTTCCCCGGCTCCCGCTCGCCGCTCG
TTCACTCCACCGCCGCCGCCGCCGCCGCCGCTGCCGCTGCCGCTGCCGCACCTCCGTAGCTGACTCGGTACTCTCTGAAGATGGCAGAAG
CTCACCAAGCTGTGGCCTTTCAGTTCACGGTCACTCCGGACGGGATTGACCTGCGGCTGAGCCATGAAGCTCTTAGACAAATCTATCTCT
CTGGACTTCATTCCTGGAAAAAGAAGTTCATCAGATTCAAGAACGGCATCATCACTGGCGTGTACCCGGCAAGCCCCTCCAGTTGGCTTA
TCGTGGTGGTGGGCGTGATGACAACGATGTACGCCAAGATCGACCCCTCGTTAGGAATAATTGCAAAAATCAATCGGACTCTGGAAACGG
CTTTCCCGGTTGGAGGAGCGGGAGTCGGAGATGAAGAAGGAGTACAATGCCCTGCACCAGCGGCACACAGAGATGATACAGACCTACGTG
GAGCACATTGAGAGGTCCAAGATGCAGCAGGTCGGAGGAAACAGCCAGACCGAGAGCAGCCTGCCGGGGCGGAGGAAGGAGCGCCCCACC
TCCCTGAACGTGTTCCCCCTGGCTGACGGCACGGTACGTGCACAGATCGGGGGCAAGCTCGTGCCTGCGGGGGACCACTGGCACCTGAGT
GACCTCGGCCAGCTGCAGTCCAGCTCCAGCTACCAGTGTCCACAGGATGAAATGTCCGAGTCAGGCCAGTCCTCGGCGGCCGCCACACCC
AGCACCACAGGCACCAAGTCCAACACGCCCACATCCTCCGTGCCCTCGGCCGCCGTCACACCCCTCAACGAGAGCCTGCAGCCCCTGGGG
GACTATGGCGTGGGCTCCAAGAACAGCAAGCGTGCCCGGGAGAAGCGCGACAGCCGCAACATGGAAGTACAGGTCACCCAGGAGATGCGC
AACGTCAGTATAGGCATGGGCAGCAGTGACGAGTGGTCTGATGTTCAAGACATTATTGACTCCACGCCAGAGCTGGACATGTGTCCAGAG
ACCCGCCTGGACCGCACAGGAAGCAGCCCAACCCAGGGCATCGTGAACAAAGCTTTCGGCATCAACACCGACTCCCTGTACCATGAGCTG
TCGACGGCAGGGTCTGAGGTCATCGGGGATGTGGACGAAGGGGCCGACCTCCTAGGGGAGTTCTCAGTGCGCGATGATTTCTTTGGAATG
GGCAAAGAAGTGGGGAATCTGCTACTGGAAAACTCACAGCTTCTGGAAACCAAAAACGCCTTGAATGTGGTGAAGAATGACCTGATTGCC
AAGGTCGACCAGCTGTCCGGGGAGCAGGAGGTGCTGAGGGGCGAGTTGGAGGCTGCTAAGCAGGCCAAAGTCAAGCTGGAAAACCGTATC
AAGGAGCTGGAAGAGGAACTGAAAAGAGTGAAGTCCGAGGCCATCATCGCCCGCCGTGAACCCAAAGAAGAGGCGGAGGATGTAAGCAGC
TATCTCTGTACAGAATCGGACAAAATCCCCATGGCCCAGCGCCGCCGCTTCACGCGGGTGGAGATGGCCCGTGTGCTCATGGAGCGGAAC
CAGTACAAGGAGCGGCTGATGGAGCTGCAGGAGGCTGTGCGGTGGACTGAGATGATCAGAGCGTCCCGAGAGCACCCATCCGTCCAGGAG
AAGAAGAAGTCGACCATCTGGCAGTTCTTCAGCCGCCTCTTCAGCTCTTCCTCCAGCCCCCCTCCGGCCAAGCGCCCCTATCCCTCGGTG
AACATCCACTACAAGTCACCCACCACTGCCGGCTTCAGCCAGCGCCGCAACCATGCCATGTGCCCGATCTCGGCAGGCAGCCGGCCCCTG
GAATTCTTCCCTGACGACGACTGCACGTCCTCCGCCCGTCGAGAGCAGAAGCGCGAGCAGTACCGCCAGGTGCGTGAGCACGTGCGTAAC
GACGACGGCCGTCTGCAGGCCTGCGGCTGGAGCCTGCCCGCCAAGTACAAGCAGCTGAGTCCCAACGGGGGCCAGGAGGACACGCGGATG
AAGAACGTGCCGGTGCCGGTGTACTGCCGCCCTCTGGTGGAGAAGGACCCCACCATGAAGCTGTGGTGTGCCGCGGGCGTCAACCTGAGC
GGGTGGAGGCCCAATGAGGACGACGCTGGGAATGGAGTCAAGCCAGCGCCAGGCCGCGATCCCCTGACCTGCGACCGCGAAGGAGACGGC
GAGCCCAAGAGCGCCCACACGTCTCCCGAGAAGAAGAAGGCCAAGGAGCTCCCTGAAATGGACGCCACCTCCAGCCGGGTGTGGATCCTG
ACCAGCACCCTGACCACCAGCAAGGTGGTGATCATCGACGCCAACCAGCCGGGCACGGTGGTGGACCAGTTCACCGTCTGCAACGCGCAC
GTGCTGTGCATCTCCAGCATCCCCGCGGCCAGCGACAGCGACTACCCTCCCGGGGAGATGTTCCTGGACAGCGACGTGAACCCAGAGGAC
CCGGGCGCAGATGGCGTGCTGGCCGGTATCACCCTGGTGGGCTGTGCCACCCGCTGCAACGTGCCGCGGAGCAACTGCTCCTCCCGAGGG
GACACCCCAGTGCTAGACAAGGGGCAGGGGGAGGTGGCCACCATCGCCAACGGGAAGGTCAACCCGTCCCAGTCCACAGAGGAGGCCACA
GAGGCCACGGAGGTGCCAGACCCTGGGCCCAGCGAGCCAGAGACAGCCACATTGCGGCCCGGGCCTCTCACAGAGCACGTCTTCACTGAC
CCAGCCCCGACCCCGTCCTCTGGCCCCCAGCCTGGCAGCGAGAACGGGCCAGAGCCTGACAGCAGCAGCACACGGCCAGAGCCAGAGCCC
AGCGGGGACCCCACGGGAGCAGGCAGCAGTGCTGCACCCACCATGTGGCTGGGAGCCCAGAACGGCTGGCTCTATGTGCACTCGGCTGTG
GCCAACTGGAAGAAGTGCCTGCACTCCATCAAGCTGAAGGATTCTGTGCTGAGCCTGGTGCATGTCAAAGGCCGTGTGCTGGTGGCTCTG
GCGGACGGGACCCTGGCCATCTTCCACCGTGGTGAAGATGGCCAGTGGGATCTGAGCAACTATCACCTAATGGACCTGGGCCACCCGCAC
CACTCCATCCGCTGCATGGCTGTTGTGTACGACCGCGTGTGGTGTGGCTACAAGAACAAGGTGCACGTCATCCAGCCCAAGACCATGCAG
ATAGAGAAGTCATTTGACGCCCACCCGCGGCGGGAGAGCCAGGTGCGGCAGCTGGCGTGGATCGGCGATGGCGTATGGGTGTCCATCCGC
CTGGACTCCACCCTGAGGCTCTACCATGCACACACGCACCAGCATCTACAGGACGTGGACATTGAGCCCTACGTCAGCAAGATGCTAGGC
ACTGGCAAGCTGGGTTTCTCCTTCGTACGCATCACGGCCCTGCTTGTCGCGGGCAGCCGGCTCTGGGTGGGCACCGGCAACGGAGTGGTC
ATCTCCATCCCCCTGACAGAGACTGTGGTCCTGCACCGAGGCCAGCTCCTGGGGCTCCGAGCCAATAAGACATCCCCCACCTCTGGGGAG
GGCGCCCGTCCCGGGGGCATCATCCACGTGTATGGCGATGACAGCAGTGACAGGGCGGCCAGCAGCTTCATCCCCTACTGCTCCATGGCC
CAGGCCCAGCTATGCTTCCATGGGCACCGCGATGCCGTGAAGTTCTTTGTCTCGGTGCCAGGGAACGTGCTGGCCACCCTGAATGGGAGT
GTGCTGGACAGCCCAGCCGAGGGCCCTGGGCCAGCTGCCCCTGCCTCGGAGGTCGAGGGCCAGAAGCTGCGGAACGTGCTGGTGCTGAGC
GGCGGGGAGGGCTACATCGACTTCCGCATTGGAGACGGAGAGGACGACGAGACGGAGGAGGGCGCAGGGGACATGAGCCAGGTGAAGCCC
GTGCTGTCCAAGGCAGAGCGCAGTCACATCATCGTGTGGCAGGTGTCCTACACCCCCGAGTGAAGCTGCTGCCCTGCCTGGCCCGACCTG
TACATAGGACCCCCGACCACCTGACCCCCGCCCGGCCCGCGGGGTAGCCAGCCAGGCGCCGCCGCCCCTCTTCTAACCTCTCAACCTGCA
GCTTTCACCTGAGTCTGGCCCCTCCAGCGGGCAGGGAGTGCGGGGATGCGGATCAGCTGGGAGGAGGAGGGGAGGGGAACTTCCACCCGA
GGGGAAGATGCTCTCGGGACAGTTTCCCGGGCAGCTCCTGGCCAGCTTCCAGCCCAGAGTCCTCAAGTCCAGGGCACCTTGGGCCCAGCG
CAGGCAGAATCCGAGGTGGTCCTGGCTCTACCCTGGGCCTCCTACTCCCCAGCACCCCTGGAGGAGGCAGGGGCTCCCCGCCGCCGAGGC
TGCCTGCCCTGGGCCCACCTCTGCATGCTGCTCATGGGGCCACCCTGCCTCCTGGGCCCTCACTCTGCCTAGGGGAGCTGGGCCAGGCAC
TAGCCTTTGCCCAGGGAGGTGGGCCTCAGGCTGCCCAGGTGCCTGCACCCCAGCCGGCCTTCTCTGGGGCCTCCCCGTCGTCAAGCCTCT
ATCCTGTCTGTCCCCACCCCAGCTGTCCCCTGCCCAGGGAGCTGGCATAAAAGCACGAGGCCCGGCTCCCTGGGGCAGCTGCTTGAGAAC
AGAGACTGCTACCCCATCCTGCCCATGCAGGCAGGCTCTTGCCAGCCCCGTTCTGACCCGTGTCCCCCCAGGCTCTGCCTGGGCAGAAGA
CTCACCTTGGAGGAGTGGGCCCTGGAGTCCTGTCCCTCCCAGAAGCCCCCAGGGTGGGATTTCTCAGGCTGCCAGGGCAGGCCCAGGCCT
CAGGAAGAAGGGGAGGCCCCTGGCCTCTCCGGGATCAGTCCTAGGACACAGGCTCAGCCTCAGGTTGATGGGGGATGATGTGCTCCCGGG
GCCTGCCTCCTGCACGGGGCTCCACGGAGCCCAGCTCCCAGACACGCTACTAAGTGCCTAGGGTTGCCCGCTGTGGCCTGCTTCCAGGGA
GCAACAGAGAGGCCACCAAGCAGAGGCCCGTGGGGCTGAGGATGGAGCCGCCCCCAGCCGACTCCAAGCCCGCAGAGGGCAGACGCCACC
CTGGACTGCTCTCCCTGCCCAGCTGGGCCTCTCTGGCCTATTCCTACCTTCCAGGCCCACTGCACTCCTGTCTGGGAGGCCCTTATGAGG
GCAGCCCAGCCCCCGCACCCACCCCCAACCAGAGAAGCACAGATCTTGGGGAGCTGCCCCACAAGCCCCGCTGGCCACCGAGGGCTGCAG
CCGCTGCGCTGCCGGCTTCTCCCCACCACCCTGCCACCTCCACTGTGATGTATGTCCGCTCCCTCGTCTGTTCCCCCAGGATCTCGAAGT
GACTCCGGGCTGAGCAGTGGGGCGGCTGGGGGAGGGGTGACGATTCTCCTCAGGCTTTGGCCCTGCAAGCAAACCCACATATCTGCTCTG
TATGTAATAAATGTCTTAACGTCGTA

>19223_19223_3_CPT1A-MAPK8IP3_CPT1A_chr11_68579905_ENST00000376618_MAPK8IP3_chr16_1779139_ENST00000250894_length(amino acids)=1200AA_BP=11
MQKSIGLWKRLSRLEERESEMKKEYNALHQRHTEMIQTYVEHIERSKMQQVGGNSQTESSLPGRRKERPTSLNVFPLADGTVRAQIGGKL
VPAGDHWHLSDLGQLQSSSSYQCPQDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQPLGDYGVGSKNSKRAREKRDSRN
MEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDMCPETRLDRTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGE
FSVRDDFFGMGKEVGNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLRGELEAAKQAKVKLENRIKELEEELKRVKSEAIIARRE
PKEEAEDVSSYLCTESDKIPMAQRRRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASREHPSVQEKKKSTIWQFFSRLFSSSSSP
PPAKRPYPSVNIHYKSPTTAGFSQRRNHAMCPISAGSRPLEFFPDDDCTSSARREQKREQYRQVREHVRNDDGRLQACGWSLPAKYKQLS
PNGGQEDTRMKNVPVPVYCRPLVEKDPTMKLWCAAGVNLSGWRPNEDDAGNGVKPAPGRDPLTCDREGDGEPKSAHTSPEKKKAKELPEM
DATSSRVWILTSTLTTSKVVIIDANQPGTVVDQFTVCNAHVLCISSIPAASDSDYPPGEMFLDSDVNPEDPGADGVLAGITLVGCATRCN
VPRSNCSSRGDTPVLDKGQGEVATIANGKVNPSQSTEEATEATEVPDPGPSEPETATLRPGPLTEHVFTDPAPTPSSGPQPGSENGPEPD
SSSTRPEPEPSGDPTGAGSSAAPTMWLGAQNGWLYVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGEDGQWDLSN
YHLMDLGHPHHSIRCMAVVYDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVD
IEPYVSKMLGTGKLGFSFVRITALLVAGSRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKTSPTSGEGARPGGIIHVYGDDSSDRAA
SSFIPYCSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDSPAEGPGPAAPASEVEGQKLRNVLVLSGGEGYIDFRIGDGEDDETEE
GAGDMSQVKPVLSKAERSHIIVWQVSYTPE

--------------------------------------------------------------
>19223_19223_4_CPT1A-MAPK8IP3_CPT1A_chr11_68579905_ENST00000376618_MAPK8IP3_chr16_1779139_ENST00000356010_length(transcript)=4321nt_BP=451nt
GGACCCGCCTCAGCCAATCCGCTGCTGCCGGCGTCGGGTGCGCTCGGCCTCGCCCGCGGCCCTCCTTCCCCGGCTCCCGCTCGCCGCTCG
TTCACTCCACCGCCGCCGCCGCCGCCGCCGCTGCCGCTGCCGCTGCCGCACCTCCGTAGCTGACTCGGTACTCTCTGAAGATGGCAGAAG
CTCACCAAGCTGTGGCCTTTCAGTTCACGGTCACTCCGGACGGGATTGACCTGCGGCTGAGCCATGAAGCTCTTAGACAAATCTATCTCT
CTGGACTTCATTCCTGGAAAAAGAAGTTCATCAGATTCAAGAACGGCATCATCACTGGCGTGTACCCGGCAAGCCCCTCCAGTTGGCTTA
TCGTGGTGGTGGGCGTGATGACAACGATGTACGCCAAGATCGACCCCTCGTTAGGAATAATTGCAAAAATCAATCGGACTCTGGAAACGG
CTTTCCCGGTTGGAGGAGCGGGAGTCGGAGATGAAGAAGGAGTACAATGCCCTGCACCAGCGGCACACAGAGATGATACAGACCTACGTG
GAGCACATTGAGAGGTCCAAGATGCAGCAGGTCGGAGGAAACAGCCAGACCGAGAGCAGCCTGCCGGGGCGGAGGAAGGAGCGCCCCACC
TCCCTGAACGTGTTCCCCCTGGCTGACGGCACGGTACGTGCACAGATCGGGGGCAAGCTCGTGCCTGCGGGGGACCACTGGCACCTGAGT
GACCTCGGCCAGCTGCAGTCCAGCTCCAGCTACCAGTGTCCACAGGATGAAATGTCCGAGTCAGGCCAGTCCTCGGCGGCCGCCACACCC
AGCACCACAGGCACCAAGTCCAACACGCCCACATCCTCCGTGCCCTCGGCCGCCGTCACACCCCTCAACGAGAGCCTGCAGCCCCTGGGG
GACTATGGCGTGGGCTCCAAGAACAGCAAGCGTGCCCGGGAGAAGCGCGACAGCCGCAACATGGAAGTACAGGTCACCCAGGAGATGCGC
AACGTCAGTATAGGCATGGGCAGCAGTGACGAGTGGTCTGATGTTCAAGACATTATTGACTCCACGCCAGAGCTGGACATGTGTCCAGAG
ACCCGCCTGGACCGCACAGGAAGCAGCCCAACCCAGGGCATCGTGAACAAAGCTTTCGGCATCAACACCGACTCCCTGTACCATGAGCTG
TCGACGGCAGGGTCTGAGGTCATCGGGGATGTGGACGAAGGGGCCGACCTCCTAGGGGAGTTCTCAGGAATGGGCAAAGAAGTGGGGAAT
CTGCTACTGGAAAACTCACAGCTTCTGGAAACCAAAAACGCCTTGAATGTGGTGAAGAATGACCTGATTGCCAAGGTCGACCAGCTGTCC
GGGGAGCAGGAGGTGCTGAGGGGCGAGTTGGAGGCTGCTAAGCAGGCCAAAGTCAAGCTGGAAAACCGTATCAAGGAGCTGGAAGAGGAA
CTGAAAAGAGTGAAGTCCGAGGCCATCATCGCCCGCCGTGAACCCAAAGAAGAGGCGGAGGATGTAAGCAGCTATCTCTGTACAGAATCG
GACAAAATCCCCATGGCCCAGCGCCGCCGCTTCACGCGGGTGGAGATGGCCCGTGTGCTCATGGAGCGGAACCAGTACAAGGAGCGGCTG
ATGGAGCTGCAGGAGGCTGTGCGGTGGACTGAGATGATCAGAGCGTCCCGAGAGCACCCATCCGTCCAGGAGAAGAAGAAGTCGACCATC
TGGCAGTTCTTCAGCCGCCTCTTCAGCTCTTCCTCCAGCCCCCCTCCGGCCAAGCGCCCCTATCCCTCGGTGAACATCCACTACAAGTCA
CCCACCACTGCCGGCTTCAGCCAGCGCCGCAACCATGCCATGTGCCCGATCTCGGCAGGCAGCCGGCCCCTGGAATTCTTCCCTGACGAC
GACTGCACGTCCTCCGCCCGTCGAGAGCAGAAGCGCGAGCAGTACCGCCAGGTGCGTGAGCACGTGCGTAACGACGACGGCCGTCTGCAG
GCCTGCGGCTGGAGCCTGCCCGCCAAGTACAAGCAGCTGAGTCCCAACGGGGGCCAGGAGGACACGCGGATGAAGAACGTGCCGGTGCCG
GTGTACTGCCGCCCTCTGGTGGAGAAGGACCCCACCATGAAGCTGTGGTGTGCCGCGGGCGTCAACCTGAGCGGGTGGAGGCCCAATGAG
GACGACGCTGGGAATGGAGTCAAGCCAGCGCCAGGCCGCGATCCCCTGACCTGCGACCGCGAAGGAGACGGCGAGCCCAAGAGCGCCCAC
ACGTCTCCCGAGAAGAAGAAGGCCAAGGAGCTCCCTGAAATGGACGCCACCTCCAGCCGGGTGTGGATCCTGACCAGCACCCTGACCACC
AGCAAGGTGGTGATCATCGACGCCAACCAGCCGGGCACGGTGGTGGACCAGTTCACCGTCTGCAACGCGCACGTGCTGTGCATCTCCAGC
ATCCCCGCGGCCAGCGACAGCGACTACCCTCCCGGGGAGATGTTCCTGGACAGCGACGTGAACCCAGAGGACCCGGGCGCAGATGGCGTG
CTGGCCGGTATCACCCTGGTGGGCTGTGCCACCCGCTGCAACGTGCCGCGGAGCAACTGCTCCTCCCGAGGGGACACCCCAGTGCTAGAC
AAGGGGCAGGGGGAGGTGGCCACCATCGCCAACGGGAAGGTCAACCCGTCCCAGTCCACAGAGGAGGCCACAGAGGCCACGGAGGTGCCA
GACCCTGGGCCCAGCGAGCCAGAGACAGCCACATTGCGGCCCGGGCCTCTCACAGAGCACGTCTTCACTGACCCAGCCCCGACCCCGTCC
TCTGGCCCCCAGCCTGGCAGCGAGAACGGGCCAGAGCCTGACAGCAGCAGCACACGGCCAGAGCCAGAGCCCAGCGGGGACCCCACGGGA
GCAGGCAGCAGTGCTGCACCCACCATGTGGCTGGGAGCCCAGAACGGCTGGCTCTATGTGCACTCGGCTGTGGCCAACTGGAAGAAGTGC
CTGCACTCCATCAAGCTGAAGGATTCTGTGCTGAGCCTGGTGCATGTCAAAGGCCGTGTGCTGGTGGCTCTGGCGGACGGGACCCTGGCC
ATCTTCCACCGTGGTGAAGATGGCCAGTGGGATCTGAGCAACTATCACCTAATGGACCTGGGCCACCCGCACCACTCCATCCGCTGCATG
GCTGTTGTGTACGACCGCGTGTGGTGTGGCTACAAGAACAAGGTGCACGTCATCCAGCCCAAGACCATGCAGATAGAGAAGTCATTTGAC
GCCCACCCGCGGCGGGAGAGCCAGGTGCGGCAGCTGGCGTGGATCGGCGATGGCGTATGGGTGTCCATCCGCCTGGACTCCACCCTGAGG
CTCTACCATGCACACACGCACCAGCATCTACAGGACGTGGACATTGAGCCCTACGTCAGCAAGATGCTAGGCACTGGCAAGCTGGGTTTC
TCCTTCGTACGCATCACGGCCCTGCTTGTCGCGGGCAGCCGGCTCTGGGTGGGCACCGGCAACGGAGTGGTCATCTCCATCCCCCTGACA
GAGACTGTGGTCCTGCACCGAGGCCAGCTCCTGGGGCTCCGAGCCAATAAGACATCCCCCACCTCTGGGGAGGGCGCCCGTCCCGGGGGC
ATCATCCACGTGTATGGCGATGACAGCAGTGACAGGGCGGCCAGCAGCTTCATCCCCTACTGCTCCATGGCCCAGGCCCAGCTATGCTTC
CATGGGCACCGCGATGCCGTGAAGTTCTTTGTCTCGGTGCCAGGGAACGTGCTGGCCACCCTGAATGGGAGTGTGCTGGACAGCCCAGCC
GAGGGCCCTGGGCCAGCTGCCCCTGCCTCGGAGGTCGAGGGCCAGAAGCTGCGGAACGTGCTGGTGCTGAGCGGCGGGGAGGGCTACATC
GACTTCCGCATTGGAGACGGAGAGGACGACGAGACGGAGGAGGGCGCAGGGGACATGAGCCAGGTGAAGCCCGTGCTGTCCAAGGCAGAG
CGCAGTCACATCATCGTGTGGCAGGTGTCCTACACCCCCGAGTGAAGCTGCTGCCCTGCCTGGCCCGACCTGTACATAGGACCCCCGACC
ACCTGACCCCCGCCCGGCCCGCGGGGTAGCCAGCCAGGCGCCGCCGCCCCTCTTCTAACCTCTCAACCTGCAGCTTTCACCTGAGTCTGG
CCCCTCCAGCGGGCAGGGAGTGCGGGGATGCGGATCAGCTGGGAGGAGGAGGGGAGGGGAACTTCCACCCGAGGGGAAGATGCTCTCGGG
ACAGTTTCCCGGGCAGCTCCTGGCCAGCTTCCAGCCCAGAGTCCTCAAGTCCAGGGCACCTTGGGCCCAGCGCAGGCAGAATCCGAGGTG
G

>19223_19223_4_CPT1A-MAPK8IP3_CPT1A_chr11_68579905_ENST00000376618_MAPK8IP3_chr16_1779139_ENST00000356010_length(amino acids)=1194AA_BP=11
MQKSIGLWKRLSRLEERESEMKKEYNALHQRHTEMIQTYVEHIERSKMQQVGGNSQTESSLPGRRKERPTSLNVFPLADGTVRAQIGGKL
VPAGDHWHLSDLGQLQSSSSYQCPQDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQPLGDYGVGSKNSKRAREKRDSRN
MEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDMCPETRLDRTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGE
FSGMGKEVGNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLRGELEAAKQAKVKLENRIKELEEELKRVKSEAIIARREPKEEAE
DVSSYLCTESDKIPMAQRRRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASREHPSVQEKKKSTIWQFFSRLFSSSSSPPPAKRP
YPSVNIHYKSPTTAGFSQRRNHAMCPISAGSRPLEFFPDDDCTSSARREQKREQYRQVREHVRNDDGRLQACGWSLPAKYKQLSPNGGQE
DTRMKNVPVPVYCRPLVEKDPTMKLWCAAGVNLSGWRPNEDDAGNGVKPAPGRDPLTCDREGDGEPKSAHTSPEKKKAKELPEMDATSSR
VWILTSTLTTSKVVIIDANQPGTVVDQFTVCNAHVLCISSIPAASDSDYPPGEMFLDSDVNPEDPGADGVLAGITLVGCATRCNVPRSNC
SSRGDTPVLDKGQGEVATIANGKVNPSQSTEEATEATEVPDPGPSEPETATLRPGPLTEHVFTDPAPTPSSGPQPGSENGPEPDSSSTRP
EPEPSGDPTGAGSSAAPTMWLGAQNGWLYVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGEDGQWDLSNYHLMDL
GHPHHSIRCMAVVYDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVS
KMLGTGKLGFSFVRITALLVAGSRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKTSPTSGEGARPGGIIHVYGDDSSDRAASSFIPY
CSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDSPAEGPGPAAPASEVEGQKLRNVLVLSGGEGYIDFRIGDGEDDETEEGAGDMS
QVKPVLSKAERSHIIVWQVSYTPE

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Fusion Gene PPI Analysis for CPT1A-MAPK8IP3

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Still interaction with
Tgene	MAPK8IP3	chr11:68579905	chr16:1779139	ENST00000250894		1	32	458_514	146.33333333333334	1337.0	NTRK2

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for CPT1A-MAPK8IP3

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for CPT1A-MAPK8IP3

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	CPT1A	C1829703	Carnitine palmitoyl transferase 1A deficiency	13	CLINGEN;CTD_human;GENOMICS_ENGLAND;UNIPROT
Hgene	CPT1A	C0002152	Alloxan Diabetes	1	CTD_human
Hgene	CPT1A	C0006142	Malignant neoplasm of breast	1	CTD_human
Hgene	CPT1A	C0011849	Diabetes Mellitus	1	CTD_human
Hgene	CPT1A	C0011853	Diabetes Mellitus, Experimental	1	CTD_human
Hgene	CPT1A	C0011860	Diabetes Mellitus, Non-Insulin-Dependent	1	CTD_human
Hgene	CPT1A	C0022661	Kidney Failure, Chronic	1	CTD_human
Hgene	CPT1A	C0038433	Streptozotocin Diabetes	1	CTD_human
Hgene	CPT1A	C0400966	Non-alcoholic Fatty Liver Disease	1	CTD_human
Hgene	CPT1A	C0678222	Breast Carcinoma	1	CTD_human
Hgene	CPT1A	C1257931	Mammary Neoplasms, Human	1	CTD_human
Hgene	CPT1A	C1458155	Mammary Neoplasms	1	CTD_human
Hgene	CPT1A	C3241937	Nonalcoholic Steatohepatitis	1	CTD_human
Hgene	CPT1A	C4704874	Mammary Carcinoma, Human	1	CTD_human
Tgene		C0032460	Polycystic Ovary Syndrome	1	CTD_human
Tgene		C0557874	Global developmental delay	1	GENOMICS_ENGLAND
Tgene		C0852413	Abnormal muscle tone	1	GENOMICS_ENGLAND
Tgene		C1136382	Sclerocystic Ovaries	1	CTD_human
Tgene		C3714756	Intellectual Disability	1	GENOMICS_ENGLAND
Tgene		C4022810	Abnormality of nervous system morphology	1	GENOMICS_ENGLAND

Fusion Gene Studies in Kim Lab

Fusion gene:CPT1A-MAPK8IP3 (FusionGDB2 ID:HG1374TG23162)

Fusion Gene Summary for CPT1A-MAPK8IP3

Fusion Gene ORF analysis for CPT1A-MAPK8IP3

Fusion Genomic Features for CPT1A-MAPK8IP3

Fusion Protein Features for CPT1A-MAPK8IP3

Fusion Gene Sequence for CPT1A-MAPK8IP3

Fusion Gene PPI Analysis for CPT1A-MAPK8IP3

Related Drugs for CPT1A-MAPK8IP3

Related Diseases for CPT1A-MAPK8IP3

Fusion Gene Studies
in Kim Lab