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Fusion Gene Summary | |
Fusion Gene ORF analysis | |
Fusion Genomic Features | |
Fusion Protein Features | |
Fusion Gene Sequence | |
Fusion Gene PPI analysis | |
Related Drugs | |
Related Diseases |
Fusion gene:CPT1A-MAPK8IP3 (FusionGDB2 ID:HG1374TG23162) |
Fusion Gene Summary for CPT1A-MAPK8IP3 |
Fusion gene summary |
Fusion gene information | Fusion gene name: CPT1A-MAPK8IP3 | Fusion gene ID: hg1374tg23162 | Hgene | Tgene | Gene symbol | CPT1A | MAPK8IP3 | Gene ID | 1374 | 23162 |
Gene name | carnitine palmitoyltransferase 1A | mitogen-activated protein kinase 8 interacting protein 3 | |
Synonyms | CPT1|CPT1-L|L-CPT1 | JIP-3|JIP3|JSAP1|NEDBA|SYD2|syd | |
Cytomap | ('CPT1A')('MAPK8IP3') 11q13.3 | 16p13.3 | |
Type of gene | protein-coding | protein-coding | |
Description | carnitine O-palmitoyltransferase 1, liver isoformCPT ICPTI-Lcarnitine O-palmitoyltransferase I, liver isoformcarnitine palmitoyltransferase 1A (liver)carnitine palmitoyltransferase I, liver | C-Jun-amino-terminal kinase-interacting protein 3C-jun-amino-terminal kinase interacting protein 3JNK MAP kinase scaffold protein 3JNK-interacting protein 3JNK/SAPK-associated protein-1JNK/stress-activated protein kinase-associated protein 1homolog | |
Modification date | 20200315 | 20200313 | |
UniProtAcc | . | . | |
Ensembl transtripts involved in fusion gene | ENST00000265641, ENST00000376618, ENST00000539743, ENST00000540367, ENST00000537756, ENST00000538994, | ||
Fusion gene scores | * DoF score | 25 X 23 X 12=6900 | 8 X 8 X 6=384 |
# samples | 32 | 9 | |
** MAII score | log2(32/6900*10)=-4.43045255166553 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/384*10)=-2.09310940439148 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: CPT1A [Title/Abstract] AND MAPK8IP3 [Title/Abstract] AND fusion [Title/Abstract] | ||
Most frequent breakpoint | CPT1A(68579905)-MAPK8IP3(1779139), # samples:1 | ||
Anticipated loss of major functional domain due to fusion event. | CPT1A-MAPK8IP3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CPT1A-MAPK8IP3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CPT1A-MAPK8IP3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CPT1A-MAPK8IP3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CPT1A-MAPK8IP3 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF. CPT1A-MAPK8IP3 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Partner | Gene | GO ID | GO term | PubMed ID |
Hgene | CPT1A | GO:0001676 | long-chain fatty acid metabolic process | 11350182 |
Hgene | CPT1A | GO:0009437 | carnitine metabolic process | 11350182 |
Fusion gene breakpoints across CPT1A (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene breakpoints across MAPK8IP3 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChimerDB4 | PAAD | TCGA-OE-A75W-01A | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
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Fusion Gene ORF analysis for CPT1A-MAPK8IP3 |
Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
5CDS-intron | ENST00000265641 | ENST00000568271 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
5CDS-intron | ENST00000376618 | ENST00000568271 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
5CDS-intron | ENST00000539743 | ENST00000568271 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
5CDS-intron | ENST00000540367 | ENST00000568271 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
Frame-shift | ENST00000539743 | ENST00000250894 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
Frame-shift | ENST00000539743 | ENST00000356010 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
Frame-shift | ENST00000540367 | ENST00000250894 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
Frame-shift | ENST00000540367 | ENST00000356010 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
In-frame | ENST00000265641 | ENST00000250894 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
In-frame | ENST00000265641 | ENST00000356010 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
In-frame | ENST00000376618 | ENST00000250894 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
In-frame | ENST00000376618 | ENST00000356010 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
intron-3CDS | ENST00000537756 | ENST00000250894 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
intron-3CDS | ENST00000537756 | ENST00000356010 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
intron-3CDS | ENST00000538994 | ENST00000250894 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
intron-3CDS | ENST00000538994 | ENST00000356010 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
intron-intron | ENST00000537756 | ENST00000568271 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
intron-intron | ENST00000538994 | ENST00000568271 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + |
ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
ENST00000376618 | CPT1A | chr11 | 68579905 | - | ENST00000250894 | MAPK8IP3 | chr16 | 1779139 | + | 5516 | 451 | 420 | 4022 | 1200 |
ENST00000376618 | CPT1A | chr11 | 68579905 | - | ENST00000356010 | MAPK8IP3 | chr16 | 1779139 | + | 4321 | 451 | 420 | 4004 | 1194 |
ENST00000265641 | CPT1A | chr11 | 68579905 | - | ENST00000250894 | MAPK8IP3 | chr16 | 1779139 | + | 5501 | 436 | 405 | 4007 | 1200 |
ENST00000265641 | CPT1A | chr11 | 68579905 | - | ENST00000356010 | MAPK8IP3 | chr16 | 1779139 | + | 4306 | 436 | 405 | 3989 | 1194 |
DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
ENST00000376618 | ENST00000250894 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + | 0.008507979 | 0.991492 |
ENST00000376618 | ENST00000356010 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + | 0.009237245 | 0.99076277 |
ENST00000265641 | ENST00000250894 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + | 0.008336654 | 0.99166334 |
ENST00000265641 | ENST00000356010 | CPT1A | chr11 | 68579905 | - | MAPK8IP3 | chr16 | 1779139 | + | 0.009017314 | 0.9909827 |
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Fusion Genomic Features for CPT1A-MAPK8IP3 |
FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
CPT1A | chr11 | 68579904 | - | MAPK8IP3 | chr16 | 1779138 | + | 6.35E-06 | 0.9999937 |
CPT1A | chr11 | 68579904 | - | MAPK8IP3 | chr16 | 1779138 | + | 6.35E-06 | 0.9999937 |
Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for CPT1A-MAPK8IP3 |
Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:68579905/chr16:1779139) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
Main function of each fusion partner protein. (from UniProt) |
Hgene | Tgene |
. | . |
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000265641 | - | 3 | 19 | 2_47 | 93 | 774.0 | Topological domain | Cytoplasmic |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000376618 | - | 3 | 19 | 2_47 | 93 | 757.0 | Topological domain | Cytoplasmic |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000539743 | - | 2 | 18 | 2_47 | 93 | 774.0 | Topological domain | Cytoplasmic |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000540367 | - | 2 | 18 | 2_47 | 93 | 757.0 | Topological domain | Cytoplasmic |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000265641 | - | 3 | 19 | 48_73 | 93 | 774.0 | Transmembrane | Helical |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000376618 | - | 3 | 19 | 48_73 | 93 | 757.0 | Transmembrane | Helical |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000539743 | - | 2 | 18 | 48_73 | 93 | 774.0 | Transmembrane | Helical |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000540367 | - | 2 | 18 | 48_73 | 93 | 757.0 | Transmembrane | Helical |
Tgene | MAPK8IP3 | chr11:68579905 | chr16:1779139 | ENST00000250894 | 1 | 32 | 440_554 | 146 | 1337.0 | Coiled coil | Ontology_term=ECO:0000255 | |
Tgene | MAPK8IP3 | chr11:68579905 | chr16:1779139 | ENST00000250894 | 1 | 32 | 520_594 | 146 | 1337.0 | Domain | RH2 | |
Tgene | MAPK8IP3 | chr11:68579905 | chr16:1779139 | ENST00000250894 | 1 | 32 | 209_225 | 146 | 1337.0 | Region | JNK-binding domain (JBD)%3B essential for its function in axon elongation | |
Tgene | MAPK8IP3 | chr11:68579905 | chr16:1779139 | ENST00000250894 | 1 | 32 | 423_458 | 146 | 1337.0 | Region | Leucine zipper-like domain (LZ)%3B essential for its function in axon elongation |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000265641 | - | 3 | 19 | 555_567 | 93 | 774.0 | Region | Coenzyme A binding |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000376618 | - | 3 | 19 | 555_567 | 93 | 757.0 | Region | Coenzyme A binding |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000539743 | - | 2 | 18 | 555_567 | 93 | 774.0 | Region | Coenzyme A binding |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000540367 | - | 2 | 18 | 555_567 | 93 | 757.0 | Region | Coenzyme A binding |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000265641 | - | 3 | 19 | 123_773 | 93 | 774.0 | Topological domain | Cytoplasmic |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000265641 | - | 3 | 19 | 74_102 | 93 | 774.0 | Topological domain | Mitochondrial intermembrane |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000376618 | - | 3 | 19 | 123_773 | 93 | 757.0 | Topological domain | Cytoplasmic |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000376618 | - | 3 | 19 | 74_102 | 93 | 757.0 | Topological domain | Mitochondrial intermembrane |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000539743 | - | 2 | 18 | 123_773 | 93 | 774.0 | Topological domain | Cytoplasmic |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000539743 | - | 2 | 18 | 74_102 | 93 | 774.0 | Topological domain | Mitochondrial intermembrane |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000540367 | - | 2 | 18 | 123_773 | 93 | 757.0 | Topological domain | Cytoplasmic |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000540367 | - | 2 | 18 | 74_102 | 93 | 757.0 | Topological domain | Mitochondrial intermembrane |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000265641 | - | 3 | 19 | 103_122 | 93 | 774.0 | Transmembrane | Helical |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000376618 | - | 3 | 19 | 103_122 | 93 | 757.0 | Transmembrane | Helical |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000539743 | - | 2 | 18 | 103_122 | 93 | 774.0 | Transmembrane | Helical |
Hgene | CPT1A | chr11:68579905 | chr16:1779139 | ENST00000540367 | - | 2 | 18 | 103_122 | 93 | 757.0 | Transmembrane | Helical |
Tgene | MAPK8IP3 | chr11:68579905 | chr16:1779139 | ENST00000250894 | 1 | 32 | 58_177 | 146 | 1337.0 | Coiled coil | Ontology_term=ECO:0000255 | |
Tgene | MAPK8IP3 | chr11:68579905 | chr16:1779139 | ENST00000250894 | 1 | 32 | 12_100 | 146 | 1337.0 | Domain | RH1 | |
Tgene | MAPK8IP3 | chr11:68579905 | chr16:1779139 | ENST00000250894 | 1 | 32 | 50_80 | 146 | 1337.0 | Region | Kinesin-binding domain (KBD)%3B essential for its function in axon elongation |
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Fusion Gene Sequence for CPT1A-MAPK8IP3 |
For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
>19223_19223_1_CPT1A-MAPK8IP3_CPT1A_chr11_68579905_ENST00000265641_MAPK8IP3_chr16_1779139_ENST00000250894_length(transcript)=5501nt_BP=436nt AATCCGCTGCTGCCGGCGTCGGGTGCGCTCGGCCTCGCCCGCGGCCCTCCTTCCCCGGCTCCCGCTCGCCGCTCGTTCACTCCACCGCCG CCGCCGCCGCCGCCGCTGCCGCTGCCGCTGCCGCACCTCCGTAGCTGACTCGGTACTCTCTGAAGATGGCAGAAGCTCACCAAGCTGTGG CCTTTCAGTTCACGGTCACTCCGGACGGGATTGACCTGCGGCTGAGCCATGAAGCTCTTAGACAAATCTATCTCTCTGGACTTCATTCCT GGAAAAAGAAGTTCATCAGATTCAAGAACGGCATCATCACTGGCGTGTACCCGGCAAGCCCCTCCAGTTGGCTTATCGTGGTGGTGGGCG TGATGACAACGATGTACGCCAAGATCGACCCCTCGTTAGGAATAATTGCAAAAATCAATCGGACTCTGGAAACGGCTTTCCCGGTTGGAG GAGCGGGAGTCGGAGATGAAGAAGGAGTACAATGCCCTGCACCAGCGGCACACAGAGATGATACAGACCTACGTGGAGCACATTGAGAGG TCCAAGATGCAGCAGGTCGGAGGAAACAGCCAGACCGAGAGCAGCCTGCCGGGGCGGAGGAAGGAGCGCCCCACCTCCCTGAACGTGTTC CCCCTGGCTGACGGCACGGTACGTGCACAGATCGGGGGCAAGCTCGTGCCTGCGGGGGACCACTGGCACCTGAGTGACCTCGGCCAGCTG CAGTCCAGCTCCAGCTACCAGTGTCCACAGGATGAAATGTCCGAGTCAGGCCAGTCCTCGGCGGCCGCCACACCCAGCACCACAGGCACC AAGTCCAACACGCCCACATCCTCCGTGCCCTCGGCCGCCGTCACACCCCTCAACGAGAGCCTGCAGCCCCTGGGGGACTATGGCGTGGGC TCCAAGAACAGCAAGCGTGCCCGGGAGAAGCGCGACAGCCGCAACATGGAAGTACAGGTCACCCAGGAGATGCGCAACGTCAGTATAGGC ATGGGCAGCAGTGACGAGTGGTCTGATGTTCAAGACATTATTGACTCCACGCCAGAGCTGGACATGTGTCCAGAGACCCGCCTGGACCGC ACAGGAAGCAGCCCAACCCAGGGCATCGTGAACAAAGCTTTCGGCATCAACACCGACTCCCTGTACCATGAGCTGTCGACGGCAGGGTCT GAGGTCATCGGGGATGTGGACGAAGGGGCCGACCTCCTAGGGGAGTTCTCAGTGCGCGATGATTTCTTTGGAATGGGCAAAGAAGTGGGG AATCTGCTACTGGAAAACTCACAGCTTCTGGAAACCAAAAACGCCTTGAATGTGGTGAAGAATGACCTGATTGCCAAGGTCGACCAGCTG TCCGGGGAGCAGGAGGTGCTGAGGGGCGAGTTGGAGGCTGCTAAGCAGGCCAAAGTCAAGCTGGAAAACCGTATCAAGGAGCTGGAAGAG GAACTGAAAAGAGTGAAGTCCGAGGCCATCATCGCCCGCCGTGAACCCAAAGAAGAGGCGGAGGATGTAAGCAGCTATCTCTGTACAGAA TCGGACAAAATCCCCATGGCCCAGCGCCGCCGCTTCACGCGGGTGGAGATGGCCCGTGTGCTCATGGAGCGGAACCAGTACAAGGAGCGG CTGATGGAGCTGCAGGAGGCTGTGCGGTGGACTGAGATGATCAGAGCGTCCCGAGAGCACCCATCCGTCCAGGAGAAGAAGAAGTCGACC ATCTGGCAGTTCTTCAGCCGCCTCTTCAGCTCTTCCTCCAGCCCCCCTCCGGCCAAGCGCCCCTATCCCTCGGTGAACATCCACTACAAG TCACCCACCACTGCCGGCTTCAGCCAGCGCCGCAACCATGCCATGTGCCCGATCTCGGCAGGCAGCCGGCCCCTGGAATTCTTCCCTGAC GACGACTGCACGTCCTCCGCCCGTCGAGAGCAGAAGCGCGAGCAGTACCGCCAGGTGCGTGAGCACGTGCGTAACGACGACGGCCGTCTG CAGGCCTGCGGCTGGAGCCTGCCCGCCAAGTACAAGCAGCTGAGTCCCAACGGGGGCCAGGAGGACACGCGGATGAAGAACGTGCCGGTG CCGGTGTACTGCCGCCCTCTGGTGGAGAAGGACCCCACCATGAAGCTGTGGTGTGCCGCGGGCGTCAACCTGAGCGGGTGGAGGCCCAAT GAGGACGACGCTGGGAATGGAGTCAAGCCAGCGCCAGGCCGCGATCCCCTGACCTGCGACCGCGAAGGAGACGGCGAGCCCAAGAGCGCC CACACGTCTCCCGAGAAGAAGAAGGCCAAGGAGCTCCCTGAAATGGACGCCACCTCCAGCCGGGTGTGGATCCTGACCAGCACCCTGACC ACCAGCAAGGTGGTGATCATCGACGCCAACCAGCCGGGCACGGTGGTGGACCAGTTCACCGTCTGCAACGCGCACGTGCTGTGCATCTCC AGCATCCCCGCGGCCAGCGACAGCGACTACCCTCCCGGGGAGATGTTCCTGGACAGCGACGTGAACCCAGAGGACCCGGGCGCAGATGGC GTGCTGGCCGGTATCACCCTGGTGGGCTGTGCCACCCGCTGCAACGTGCCGCGGAGCAACTGCTCCTCCCGAGGGGACACCCCAGTGCTA GACAAGGGGCAGGGGGAGGTGGCCACCATCGCCAACGGGAAGGTCAACCCGTCCCAGTCCACAGAGGAGGCCACAGAGGCCACGGAGGTG CCAGACCCTGGGCCCAGCGAGCCAGAGACAGCCACATTGCGGCCCGGGCCTCTCACAGAGCACGTCTTCACTGACCCAGCCCCGACCCCG TCCTCTGGCCCCCAGCCTGGCAGCGAGAACGGGCCAGAGCCTGACAGCAGCAGCACACGGCCAGAGCCAGAGCCCAGCGGGGACCCCACG GGAGCAGGCAGCAGTGCTGCACCCACCATGTGGCTGGGAGCCCAGAACGGCTGGCTCTATGTGCACTCGGCTGTGGCCAACTGGAAGAAG TGCCTGCACTCCATCAAGCTGAAGGATTCTGTGCTGAGCCTGGTGCATGTCAAAGGCCGTGTGCTGGTGGCTCTGGCGGACGGGACCCTG GCCATCTTCCACCGTGGTGAAGATGGCCAGTGGGATCTGAGCAACTATCACCTAATGGACCTGGGCCACCCGCACCACTCCATCCGCTGC ATGGCTGTTGTGTACGACCGCGTGTGGTGTGGCTACAAGAACAAGGTGCACGTCATCCAGCCCAAGACCATGCAGATAGAGAAGTCATTT GACGCCCACCCGCGGCGGGAGAGCCAGGTGCGGCAGCTGGCGTGGATCGGCGATGGCGTATGGGTGTCCATCCGCCTGGACTCCACCCTG AGGCTCTACCATGCACACACGCACCAGCATCTACAGGACGTGGACATTGAGCCCTACGTCAGCAAGATGCTAGGCACTGGCAAGCTGGGT TTCTCCTTCGTACGCATCACGGCCCTGCTTGTCGCGGGCAGCCGGCTCTGGGTGGGCACCGGCAACGGAGTGGTCATCTCCATCCCCCTG ACAGAGACTGTGGTCCTGCACCGAGGCCAGCTCCTGGGGCTCCGAGCCAATAAGACATCCCCCACCTCTGGGGAGGGCGCCCGTCCCGGG GGCATCATCCACGTGTATGGCGATGACAGCAGTGACAGGGCGGCCAGCAGCTTCATCCCCTACTGCTCCATGGCCCAGGCCCAGCTATGC TTCCATGGGCACCGCGATGCCGTGAAGTTCTTTGTCTCGGTGCCAGGGAACGTGCTGGCCACCCTGAATGGGAGTGTGCTGGACAGCCCA GCCGAGGGCCCTGGGCCAGCTGCCCCTGCCTCGGAGGTCGAGGGCCAGAAGCTGCGGAACGTGCTGGTGCTGAGCGGCGGGGAGGGCTAC ATCGACTTCCGCATTGGAGACGGAGAGGACGACGAGACGGAGGAGGGCGCAGGGGACATGAGCCAGGTGAAGCCCGTGCTGTCCAAGGCA GAGCGCAGTCACATCATCGTGTGGCAGGTGTCCTACACCCCCGAGTGAAGCTGCTGCCCTGCCTGGCCCGACCTGTACATAGGACCCCCG ACCACCTGACCCCCGCCCGGCCCGCGGGGTAGCCAGCCAGGCGCCGCCGCCCCTCTTCTAACCTCTCAACCTGCAGCTTTCACCTGAGTC TGGCCCCTCCAGCGGGCAGGGAGTGCGGGGATGCGGATCAGCTGGGAGGAGGAGGGGAGGGGAACTTCCACCCGAGGGGAAGATGCTCTC GGGACAGTTTCCCGGGCAGCTCCTGGCCAGCTTCCAGCCCAGAGTCCTCAAGTCCAGGGCACCTTGGGCCCAGCGCAGGCAGAATCCGAG GTGGTCCTGGCTCTACCCTGGGCCTCCTACTCCCCAGCACCCCTGGAGGAGGCAGGGGCTCCCCGCCGCCGAGGCTGCCTGCCCTGGGCC CACCTCTGCATGCTGCTCATGGGGCCACCCTGCCTCCTGGGCCCTCACTCTGCCTAGGGGAGCTGGGCCAGGCACTAGCCTTTGCCCAGG GAGGTGGGCCTCAGGCTGCCCAGGTGCCTGCACCCCAGCCGGCCTTCTCTGGGGCCTCCCCGTCGTCAAGCCTCTATCCTGTCTGTCCCC ACCCCAGCTGTCCCCTGCCCAGGGAGCTGGCATAAAAGCACGAGGCCCGGCTCCCTGGGGCAGCTGCTTGAGAACAGAGACTGCTACCCC ATCCTGCCCATGCAGGCAGGCTCTTGCCAGCCCCGTTCTGACCCGTGTCCCCCCAGGCTCTGCCTGGGCAGAAGACTCACCTTGGAGGAG TGGGCCCTGGAGTCCTGTCCCTCCCAGAAGCCCCCAGGGTGGGATTTCTCAGGCTGCCAGGGCAGGCCCAGGCCTCAGGAAGAAGGGGAG GCCCCTGGCCTCTCCGGGATCAGTCCTAGGACACAGGCTCAGCCTCAGGTTGATGGGGGATGATGTGCTCCCGGGGCCTGCCTCCTGCAC GGGGCTCCACGGAGCCCAGCTCCCAGACACGCTACTAAGTGCCTAGGGTTGCCCGCTGTGGCCTGCTTCCAGGGAGCAACAGAGAGGCCA CCAAGCAGAGGCCCGTGGGGCTGAGGATGGAGCCGCCCCCAGCCGACTCCAAGCCCGCAGAGGGCAGACGCCACCCTGGACTGCTCTCCC TGCCCAGCTGGGCCTCTCTGGCCTATTCCTACCTTCCAGGCCCACTGCACTCCTGTCTGGGAGGCCCTTATGAGGGCAGCCCAGCCCCCG CACCCACCCCCAACCAGAGAAGCACAGATCTTGGGGAGCTGCCCCACAAGCCCCGCTGGCCACCGAGGGCTGCAGCCGCTGCGCTGCCGG CTTCTCCCCACCACCCTGCCACCTCCACTGTGATGTATGTCCGCTCCCTCGTCTGTTCCCCCAGGATCTCGAAGTGACTCCGGGCTGAGC AGTGGGGCGGCTGGGGGAGGGGTGACGATTCTCCTCAGGCTTTGGCCCTGCAAGCAAACCCACATATCTGCTCTGTATGTAATAAATGTC >19223_19223_1_CPT1A-MAPK8IP3_CPT1A_chr11_68579905_ENST00000265641_MAPK8IP3_chr16_1779139_ENST00000250894_length(amino acids)=1200AA_BP=11 MQKSIGLWKRLSRLEERESEMKKEYNALHQRHTEMIQTYVEHIERSKMQQVGGNSQTESSLPGRRKERPTSLNVFPLADGTVRAQIGGKL VPAGDHWHLSDLGQLQSSSSYQCPQDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQPLGDYGVGSKNSKRAREKRDSRN MEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDMCPETRLDRTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGE FSVRDDFFGMGKEVGNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLRGELEAAKQAKVKLENRIKELEEELKRVKSEAIIARRE PKEEAEDVSSYLCTESDKIPMAQRRRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASREHPSVQEKKKSTIWQFFSRLFSSSSSP PPAKRPYPSVNIHYKSPTTAGFSQRRNHAMCPISAGSRPLEFFPDDDCTSSARREQKREQYRQVREHVRNDDGRLQACGWSLPAKYKQLS PNGGQEDTRMKNVPVPVYCRPLVEKDPTMKLWCAAGVNLSGWRPNEDDAGNGVKPAPGRDPLTCDREGDGEPKSAHTSPEKKKAKELPEM DATSSRVWILTSTLTTSKVVIIDANQPGTVVDQFTVCNAHVLCISSIPAASDSDYPPGEMFLDSDVNPEDPGADGVLAGITLVGCATRCN VPRSNCSSRGDTPVLDKGQGEVATIANGKVNPSQSTEEATEATEVPDPGPSEPETATLRPGPLTEHVFTDPAPTPSSGPQPGSENGPEPD SSSTRPEPEPSGDPTGAGSSAAPTMWLGAQNGWLYVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGEDGQWDLSN YHLMDLGHPHHSIRCMAVVYDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVD IEPYVSKMLGTGKLGFSFVRITALLVAGSRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKTSPTSGEGARPGGIIHVYGDDSSDRAA SSFIPYCSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDSPAEGPGPAAPASEVEGQKLRNVLVLSGGEGYIDFRIGDGEDDETEE -------------------------------------------------------------- >19223_19223_2_CPT1A-MAPK8IP3_CPT1A_chr11_68579905_ENST00000265641_MAPK8IP3_chr16_1779139_ENST00000356010_length(transcript)=4306nt_BP=436nt AATCCGCTGCTGCCGGCGTCGGGTGCGCTCGGCCTCGCCCGCGGCCCTCCTTCCCCGGCTCCCGCTCGCCGCTCGTTCACTCCACCGCCG CCGCCGCCGCCGCCGCTGCCGCTGCCGCTGCCGCACCTCCGTAGCTGACTCGGTACTCTCTGAAGATGGCAGAAGCTCACCAAGCTGTGG CCTTTCAGTTCACGGTCACTCCGGACGGGATTGACCTGCGGCTGAGCCATGAAGCTCTTAGACAAATCTATCTCTCTGGACTTCATTCCT GGAAAAAGAAGTTCATCAGATTCAAGAACGGCATCATCACTGGCGTGTACCCGGCAAGCCCCTCCAGTTGGCTTATCGTGGTGGTGGGCG TGATGACAACGATGTACGCCAAGATCGACCCCTCGTTAGGAATAATTGCAAAAATCAATCGGACTCTGGAAACGGCTTTCCCGGTTGGAG GAGCGGGAGTCGGAGATGAAGAAGGAGTACAATGCCCTGCACCAGCGGCACACAGAGATGATACAGACCTACGTGGAGCACATTGAGAGG TCCAAGATGCAGCAGGTCGGAGGAAACAGCCAGACCGAGAGCAGCCTGCCGGGGCGGAGGAAGGAGCGCCCCACCTCCCTGAACGTGTTC CCCCTGGCTGACGGCACGGTACGTGCACAGATCGGGGGCAAGCTCGTGCCTGCGGGGGACCACTGGCACCTGAGTGACCTCGGCCAGCTG CAGTCCAGCTCCAGCTACCAGTGTCCACAGGATGAAATGTCCGAGTCAGGCCAGTCCTCGGCGGCCGCCACACCCAGCACCACAGGCACC AAGTCCAACACGCCCACATCCTCCGTGCCCTCGGCCGCCGTCACACCCCTCAACGAGAGCCTGCAGCCCCTGGGGGACTATGGCGTGGGC TCCAAGAACAGCAAGCGTGCCCGGGAGAAGCGCGACAGCCGCAACATGGAAGTACAGGTCACCCAGGAGATGCGCAACGTCAGTATAGGC ATGGGCAGCAGTGACGAGTGGTCTGATGTTCAAGACATTATTGACTCCACGCCAGAGCTGGACATGTGTCCAGAGACCCGCCTGGACCGC ACAGGAAGCAGCCCAACCCAGGGCATCGTGAACAAAGCTTTCGGCATCAACACCGACTCCCTGTACCATGAGCTGTCGACGGCAGGGTCT GAGGTCATCGGGGATGTGGACGAAGGGGCCGACCTCCTAGGGGAGTTCTCAGGAATGGGCAAAGAAGTGGGGAATCTGCTACTGGAAAAC TCACAGCTTCTGGAAACCAAAAACGCCTTGAATGTGGTGAAGAATGACCTGATTGCCAAGGTCGACCAGCTGTCCGGGGAGCAGGAGGTG CTGAGGGGCGAGTTGGAGGCTGCTAAGCAGGCCAAAGTCAAGCTGGAAAACCGTATCAAGGAGCTGGAAGAGGAACTGAAAAGAGTGAAG TCCGAGGCCATCATCGCCCGCCGTGAACCCAAAGAAGAGGCGGAGGATGTAAGCAGCTATCTCTGTACAGAATCGGACAAAATCCCCATG GCCCAGCGCCGCCGCTTCACGCGGGTGGAGATGGCCCGTGTGCTCATGGAGCGGAACCAGTACAAGGAGCGGCTGATGGAGCTGCAGGAG GCTGTGCGGTGGACTGAGATGATCAGAGCGTCCCGAGAGCACCCATCCGTCCAGGAGAAGAAGAAGTCGACCATCTGGCAGTTCTTCAGC CGCCTCTTCAGCTCTTCCTCCAGCCCCCCTCCGGCCAAGCGCCCCTATCCCTCGGTGAACATCCACTACAAGTCACCCACCACTGCCGGC TTCAGCCAGCGCCGCAACCATGCCATGTGCCCGATCTCGGCAGGCAGCCGGCCCCTGGAATTCTTCCCTGACGACGACTGCACGTCCTCC GCCCGTCGAGAGCAGAAGCGCGAGCAGTACCGCCAGGTGCGTGAGCACGTGCGTAACGACGACGGCCGTCTGCAGGCCTGCGGCTGGAGC CTGCCCGCCAAGTACAAGCAGCTGAGTCCCAACGGGGGCCAGGAGGACACGCGGATGAAGAACGTGCCGGTGCCGGTGTACTGCCGCCCT CTGGTGGAGAAGGACCCCACCATGAAGCTGTGGTGTGCCGCGGGCGTCAACCTGAGCGGGTGGAGGCCCAATGAGGACGACGCTGGGAAT GGAGTCAAGCCAGCGCCAGGCCGCGATCCCCTGACCTGCGACCGCGAAGGAGACGGCGAGCCCAAGAGCGCCCACACGTCTCCCGAGAAG AAGAAGGCCAAGGAGCTCCCTGAAATGGACGCCACCTCCAGCCGGGTGTGGATCCTGACCAGCACCCTGACCACCAGCAAGGTGGTGATC ATCGACGCCAACCAGCCGGGCACGGTGGTGGACCAGTTCACCGTCTGCAACGCGCACGTGCTGTGCATCTCCAGCATCCCCGCGGCCAGC GACAGCGACTACCCTCCCGGGGAGATGTTCCTGGACAGCGACGTGAACCCAGAGGACCCGGGCGCAGATGGCGTGCTGGCCGGTATCACC CTGGTGGGCTGTGCCACCCGCTGCAACGTGCCGCGGAGCAACTGCTCCTCCCGAGGGGACACCCCAGTGCTAGACAAGGGGCAGGGGGAG GTGGCCACCATCGCCAACGGGAAGGTCAACCCGTCCCAGTCCACAGAGGAGGCCACAGAGGCCACGGAGGTGCCAGACCCTGGGCCCAGC GAGCCAGAGACAGCCACATTGCGGCCCGGGCCTCTCACAGAGCACGTCTTCACTGACCCAGCCCCGACCCCGTCCTCTGGCCCCCAGCCT GGCAGCGAGAACGGGCCAGAGCCTGACAGCAGCAGCACACGGCCAGAGCCAGAGCCCAGCGGGGACCCCACGGGAGCAGGCAGCAGTGCT GCACCCACCATGTGGCTGGGAGCCCAGAACGGCTGGCTCTATGTGCACTCGGCTGTGGCCAACTGGAAGAAGTGCCTGCACTCCATCAAG CTGAAGGATTCTGTGCTGAGCCTGGTGCATGTCAAAGGCCGTGTGCTGGTGGCTCTGGCGGACGGGACCCTGGCCATCTTCCACCGTGGT GAAGATGGCCAGTGGGATCTGAGCAACTATCACCTAATGGACCTGGGCCACCCGCACCACTCCATCCGCTGCATGGCTGTTGTGTACGAC CGCGTGTGGTGTGGCTACAAGAACAAGGTGCACGTCATCCAGCCCAAGACCATGCAGATAGAGAAGTCATTTGACGCCCACCCGCGGCGG GAGAGCCAGGTGCGGCAGCTGGCGTGGATCGGCGATGGCGTATGGGTGTCCATCCGCCTGGACTCCACCCTGAGGCTCTACCATGCACAC ACGCACCAGCATCTACAGGACGTGGACATTGAGCCCTACGTCAGCAAGATGCTAGGCACTGGCAAGCTGGGTTTCTCCTTCGTACGCATC ACGGCCCTGCTTGTCGCGGGCAGCCGGCTCTGGGTGGGCACCGGCAACGGAGTGGTCATCTCCATCCCCCTGACAGAGACTGTGGTCCTG CACCGAGGCCAGCTCCTGGGGCTCCGAGCCAATAAGACATCCCCCACCTCTGGGGAGGGCGCCCGTCCCGGGGGCATCATCCACGTGTAT GGCGATGACAGCAGTGACAGGGCGGCCAGCAGCTTCATCCCCTACTGCTCCATGGCCCAGGCCCAGCTATGCTTCCATGGGCACCGCGAT GCCGTGAAGTTCTTTGTCTCGGTGCCAGGGAACGTGCTGGCCACCCTGAATGGGAGTGTGCTGGACAGCCCAGCCGAGGGCCCTGGGCCA GCTGCCCCTGCCTCGGAGGTCGAGGGCCAGAAGCTGCGGAACGTGCTGGTGCTGAGCGGCGGGGAGGGCTACATCGACTTCCGCATTGGA GACGGAGAGGACGACGAGACGGAGGAGGGCGCAGGGGACATGAGCCAGGTGAAGCCCGTGCTGTCCAAGGCAGAGCGCAGTCACATCATC GTGTGGCAGGTGTCCTACACCCCCGAGTGAAGCTGCTGCCCTGCCTGGCCCGACCTGTACATAGGACCCCCGACCACCTGACCCCCGCCC GGCCCGCGGGGTAGCCAGCCAGGCGCCGCCGCCCCTCTTCTAACCTCTCAACCTGCAGCTTTCACCTGAGTCTGGCCCCTCCAGCGGGCA GGGAGTGCGGGGATGCGGATCAGCTGGGAGGAGGAGGGGAGGGGAACTTCCACCCGAGGGGAAGATGCTCTCGGGACAGTTTCCCGGGCA >19223_19223_2_CPT1A-MAPK8IP3_CPT1A_chr11_68579905_ENST00000265641_MAPK8IP3_chr16_1779139_ENST00000356010_length(amino acids)=1194AA_BP=11 MQKSIGLWKRLSRLEERESEMKKEYNALHQRHTEMIQTYVEHIERSKMQQVGGNSQTESSLPGRRKERPTSLNVFPLADGTVRAQIGGKL VPAGDHWHLSDLGQLQSSSSYQCPQDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQPLGDYGVGSKNSKRAREKRDSRN MEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDMCPETRLDRTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGE FSGMGKEVGNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLRGELEAAKQAKVKLENRIKELEEELKRVKSEAIIARREPKEEAE DVSSYLCTESDKIPMAQRRRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASREHPSVQEKKKSTIWQFFSRLFSSSSSPPPAKRP YPSVNIHYKSPTTAGFSQRRNHAMCPISAGSRPLEFFPDDDCTSSARREQKREQYRQVREHVRNDDGRLQACGWSLPAKYKQLSPNGGQE DTRMKNVPVPVYCRPLVEKDPTMKLWCAAGVNLSGWRPNEDDAGNGVKPAPGRDPLTCDREGDGEPKSAHTSPEKKKAKELPEMDATSSR VWILTSTLTTSKVVIIDANQPGTVVDQFTVCNAHVLCISSIPAASDSDYPPGEMFLDSDVNPEDPGADGVLAGITLVGCATRCNVPRSNC SSRGDTPVLDKGQGEVATIANGKVNPSQSTEEATEATEVPDPGPSEPETATLRPGPLTEHVFTDPAPTPSSGPQPGSENGPEPDSSSTRP EPEPSGDPTGAGSSAAPTMWLGAQNGWLYVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGEDGQWDLSNYHLMDL GHPHHSIRCMAVVYDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVS KMLGTGKLGFSFVRITALLVAGSRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKTSPTSGEGARPGGIIHVYGDDSSDRAASSFIPY CSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDSPAEGPGPAAPASEVEGQKLRNVLVLSGGEGYIDFRIGDGEDDETEEGAGDMS -------------------------------------------------------------- >19223_19223_3_CPT1A-MAPK8IP3_CPT1A_chr11_68579905_ENST00000376618_MAPK8IP3_chr16_1779139_ENST00000250894_length(transcript)=5516nt_BP=451nt GGACCCGCCTCAGCCAATCCGCTGCTGCCGGCGTCGGGTGCGCTCGGCCTCGCCCGCGGCCCTCCTTCCCCGGCTCCCGCTCGCCGCTCG TTCACTCCACCGCCGCCGCCGCCGCCGCCGCTGCCGCTGCCGCTGCCGCACCTCCGTAGCTGACTCGGTACTCTCTGAAGATGGCAGAAG CTCACCAAGCTGTGGCCTTTCAGTTCACGGTCACTCCGGACGGGATTGACCTGCGGCTGAGCCATGAAGCTCTTAGACAAATCTATCTCT CTGGACTTCATTCCTGGAAAAAGAAGTTCATCAGATTCAAGAACGGCATCATCACTGGCGTGTACCCGGCAAGCCCCTCCAGTTGGCTTA TCGTGGTGGTGGGCGTGATGACAACGATGTACGCCAAGATCGACCCCTCGTTAGGAATAATTGCAAAAATCAATCGGACTCTGGAAACGG CTTTCCCGGTTGGAGGAGCGGGAGTCGGAGATGAAGAAGGAGTACAATGCCCTGCACCAGCGGCACACAGAGATGATACAGACCTACGTG GAGCACATTGAGAGGTCCAAGATGCAGCAGGTCGGAGGAAACAGCCAGACCGAGAGCAGCCTGCCGGGGCGGAGGAAGGAGCGCCCCACC TCCCTGAACGTGTTCCCCCTGGCTGACGGCACGGTACGTGCACAGATCGGGGGCAAGCTCGTGCCTGCGGGGGACCACTGGCACCTGAGT GACCTCGGCCAGCTGCAGTCCAGCTCCAGCTACCAGTGTCCACAGGATGAAATGTCCGAGTCAGGCCAGTCCTCGGCGGCCGCCACACCC AGCACCACAGGCACCAAGTCCAACACGCCCACATCCTCCGTGCCCTCGGCCGCCGTCACACCCCTCAACGAGAGCCTGCAGCCCCTGGGG GACTATGGCGTGGGCTCCAAGAACAGCAAGCGTGCCCGGGAGAAGCGCGACAGCCGCAACATGGAAGTACAGGTCACCCAGGAGATGCGC AACGTCAGTATAGGCATGGGCAGCAGTGACGAGTGGTCTGATGTTCAAGACATTATTGACTCCACGCCAGAGCTGGACATGTGTCCAGAG ACCCGCCTGGACCGCACAGGAAGCAGCCCAACCCAGGGCATCGTGAACAAAGCTTTCGGCATCAACACCGACTCCCTGTACCATGAGCTG TCGACGGCAGGGTCTGAGGTCATCGGGGATGTGGACGAAGGGGCCGACCTCCTAGGGGAGTTCTCAGTGCGCGATGATTTCTTTGGAATG GGCAAAGAAGTGGGGAATCTGCTACTGGAAAACTCACAGCTTCTGGAAACCAAAAACGCCTTGAATGTGGTGAAGAATGACCTGATTGCC AAGGTCGACCAGCTGTCCGGGGAGCAGGAGGTGCTGAGGGGCGAGTTGGAGGCTGCTAAGCAGGCCAAAGTCAAGCTGGAAAACCGTATC AAGGAGCTGGAAGAGGAACTGAAAAGAGTGAAGTCCGAGGCCATCATCGCCCGCCGTGAACCCAAAGAAGAGGCGGAGGATGTAAGCAGC TATCTCTGTACAGAATCGGACAAAATCCCCATGGCCCAGCGCCGCCGCTTCACGCGGGTGGAGATGGCCCGTGTGCTCATGGAGCGGAAC CAGTACAAGGAGCGGCTGATGGAGCTGCAGGAGGCTGTGCGGTGGACTGAGATGATCAGAGCGTCCCGAGAGCACCCATCCGTCCAGGAG AAGAAGAAGTCGACCATCTGGCAGTTCTTCAGCCGCCTCTTCAGCTCTTCCTCCAGCCCCCCTCCGGCCAAGCGCCCCTATCCCTCGGTG AACATCCACTACAAGTCACCCACCACTGCCGGCTTCAGCCAGCGCCGCAACCATGCCATGTGCCCGATCTCGGCAGGCAGCCGGCCCCTG GAATTCTTCCCTGACGACGACTGCACGTCCTCCGCCCGTCGAGAGCAGAAGCGCGAGCAGTACCGCCAGGTGCGTGAGCACGTGCGTAAC GACGACGGCCGTCTGCAGGCCTGCGGCTGGAGCCTGCCCGCCAAGTACAAGCAGCTGAGTCCCAACGGGGGCCAGGAGGACACGCGGATG AAGAACGTGCCGGTGCCGGTGTACTGCCGCCCTCTGGTGGAGAAGGACCCCACCATGAAGCTGTGGTGTGCCGCGGGCGTCAACCTGAGC GGGTGGAGGCCCAATGAGGACGACGCTGGGAATGGAGTCAAGCCAGCGCCAGGCCGCGATCCCCTGACCTGCGACCGCGAAGGAGACGGC GAGCCCAAGAGCGCCCACACGTCTCCCGAGAAGAAGAAGGCCAAGGAGCTCCCTGAAATGGACGCCACCTCCAGCCGGGTGTGGATCCTG ACCAGCACCCTGACCACCAGCAAGGTGGTGATCATCGACGCCAACCAGCCGGGCACGGTGGTGGACCAGTTCACCGTCTGCAACGCGCAC GTGCTGTGCATCTCCAGCATCCCCGCGGCCAGCGACAGCGACTACCCTCCCGGGGAGATGTTCCTGGACAGCGACGTGAACCCAGAGGAC CCGGGCGCAGATGGCGTGCTGGCCGGTATCACCCTGGTGGGCTGTGCCACCCGCTGCAACGTGCCGCGGAGCAACTGCTCCTCCCGAGGG GACACCCCAGTGCTAGACAAGGGGCAGGGGGAGGTGGCCACCATCGCCAACGGGAAGGTCAACCCGTCCCAGTCCACAGAGGAGGCCACA GAGGCCACGGAGGTGCCAGACCCTGGGCCCAGCGAGCCAGAGACAGCCACATTGCGGCCCGGGCCTCTCACAGAGCACGTCTTCACTGAC CCAGCCCCGACCCCGTCCTCTGGCCCCCAGCCTGGCAGCGAGAACGGGCCAGAGCCTGACAGCAGCAGCACACGGCCAGAGCCAGAGCCC AGCGGGGACCCCACGGGAGCAGGCAGCAGTGCTGCACCCACCATGTGGCTGGGAGCCCAGAACGGCTGGCTCTATGTGCACTCGGCTGTG GCCAACTGGAAGAAGTGCCTGCACTCCATCAAGCTGAAGGATTCTGTGCTGAGCCTGGTGCATGTCAAAGGCCGTGTGCTGGTGGCTCTG GCGGACGGGACCCTGGCCATCTTCCACCGTGGTGAAGATGGCCAGTGGGATCTGAGCAACTATCACCTAATGGACCTGGGCCACCCGCAC CACTCCATCCGCTGCATGGCTGTTGTGTACGACCGCGTGTGGTGTGGCTACAAGAACAAGGTGCACGTCATCCAGCCCAAGACCATGCAG ATAGAGAAGTCATTTGACGCCCACCCGCGGCGGGAGAGCCAGGTGCGGCAGCTGGCGTGGATCGGCGATGGCGTATGGGTGTCCATCCGC CTGGACTCCACCCTGAGGCTCTACCATGCACACACGCACCAGCATCTACAGGACGTGGACATTGAGCCCTACGTCAGCAAGATGCTAGGC ACTGGCAAGCTGGGTTTCTCCTTCGTACGCATCACGGCCCTGCTTGTCGCGGGCAGCCGGCTCTGGGTGGGCACCGGCAACGGAGTGGTC ATCTCCATCCCCCTGACAGAGACTGTGGTCCTGCACCGAGGCCAGCTCCTGGGGCTCCGAGCCAATAAGACATCCCCCACCTCTGGGGAG GGCGCCCGTCCCGGGGGCATCATCCACGTGTATGGCGATGACAGCAGTGACAGGGCGGCCAGCAGCTTCATCCCCTACTGCTCCATGGCC CAGGCCCAGCTATGCTTCCATGGGCACCGCGATGCCGTGAAGTTCTTTGTCTCGGTGCCAGGGAACGTGCTGGCCACCCTGAATGGGAGT GTGCTGGACAGCCCAGCCGAGGGCCCTGGGCCAGCTGCCCCTGCCTCGGAGGTCGAGGGCCAGAAGCTGCGGAACGTGCTGGTGCTGAGC GGCGGGGAGGGCTACATCGACTTCCGCATTGGAGACGGAGAGGACGACGAGACGGAGGAGGGCGCAGGGGACATGAGCCAGGTGAAGCCC GTGCTGTCCAAGGCAGAGCGCAGTCACATCATCGTGTGGCAGGTGTCCTACACCCCCGAGTGAAGCTGCTGCCCTGCCTGGCCCGACCTG TACATAGGACCCCCGACCACCTGACCCCCGCCCGGCCCGCGGGGTAGCCAGCCAGGCGCCGCCGCCCCTCTTCTAACCTCTCAACCTGCA GCTTTCACCTGAGTCTGGCCCCTCCAGCGGGCAGGGAGTGCGGGGATGCGGATCAGCTGGGAGGAGGAGGGGAGGGGAACTTCCACCCGA GGGGAAGATGCTCTCGGGACAGTTTCCCGGGCAGCTCCTGGCCAGCTTCCAGCCCAGAGTCCTCAAGTCCAGGGCACCTTGGGCCCAGCG CAGGCAGAATCCGAGGTGGTCCTGGCTCTACCCTGGGCCTCCTACTCCCCAGCACCCCTGGAGGAGGCAGGGGCTCCCCGCCGCCGAGGC TGCCTGCCCTGGGCCCACCTCTGCATGCTGCTCATGGGGCCACCCTGCCTCCTGGGCCCTCACTCTGCCTAGGGGAGCTGGGCCAGGCAC TAGCCTTTGCCCAGGGAGGTGGGCCTCAGGCTGCCCAGGTGCCTGCACCCCAGCCGGCCTTCTCTGGGGCCTCCCCGTCGTCAAGCCTCT ATCCTGTCTGTCCCCACCCCAGCTGTCCCCTGCCCAGGGAGCTGGCATAAAAGCACGAGGCCCGGCTCCCTGGGGCAGCTGCTTGAGAAC AGAGACTGCTACCCCATCCTGCCCATGCAGGCAGGCTCTTGCCAGCCCCGTTCTGACCCGTGTCCCCCCAGGCTCTGCCTGGGCAGAAGA CTCACCTTGGAGGAGTGGGCCCTGGAGTCCTGTCCCTCCCAGAAGCCCCCAGGGTGGGATTTCTCAGGCTGCCAGGGCAGGCCCAGGCCT CAGGAAGAAGGGGAGGCCCCTGGCCTCTCCGGGATCAGTCCTAGGACACAGGCTCAGCCTCAGGTTGATGGGGGATGATGTGCTCCCGGG GCCTGCCTCCTGCACGGGGCTCCACGGAGCCCAGCTCCCAGACACGCTACTAAGTGCCTAGGGTTGCCCGCTGTGGCCTGCTTCCAGGGA GCAACAGAGAGGCCACCAAGCAGAGGCCCGTGGGGCTGAGGATGGAGCCGCCCCCAGCCGACTCCAAGCCCGCAGAGGGCAGACGCCACC CTGGACTGCTCTCCCTGCCCAGCTGGGCCTCTCTGGCCTATTCCTACCTTCCAGGCCCACTGCACTCCTGTCTGGGAGGCCCTTATGAGG GCAGCCCAGCCCCCGCACCCACCCCCAACCAGAGAAGCACAGATCTTGGGGAGCTGCCCCACAAGCCCCGCTGGCCACCGAGGGCTGCAG CCGCTGCGCTGCCGGCTTCTCCCCACCACCCTGCCACCTCCACTGTGATGTATGTCCGCTCCCTCGTCTGTTCCCCCAGGATCTCGAAGT GACTCCGGGCTGAGCAGTGGGGCGGCTGGGGGAGGGGTGACGATTCTCCTCAGGCTTTGGCCCTGCAAGCAAACCCACATATCTGCTCTG >19223_19223_3_CPT1A-MAPK8IP3_CPT1A_chr11_68579905_ENST00000376618_MAPK8IP3_chr16_1779139_ENST00000250894_length(amino acids)=1200AA_BP=11 MQKSIGLWKRLSRLEERESEMKKEYNALHQRHTEMIQTYVEHIERSKMQQVGGNSQTESSLPGRRKERPTSLNVFPLADGTVRAQIGGKL VPAGDHWHLSDLGQLQSSSSYQCPQDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQPLGDYGVGSKNSKRAREKRDSRN MEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDMCPETRLDRTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGE FSVRDDFFGMGKEVGNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLRGELEAAKQAKVKLENRIKELEEELKRVKSEAIIARRE PKEEAEDVSSYLCTESDKIPMAQRRRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASREHPSVQEKKKSTIWQFFSRLFSSSSSP PPAKRPYPSVNIHYKSPTTAGFSQRRNHAMCPISAGSRPLEFFPDDDCTSSARREQKREQYRQVREHVRNDDGRLQACGWSLPAKYKQLS PNGGQEDTRMKNVPVPVYCRPLVEKDPTMKLWCAAGVNLSGWRPNEDDAGNGVKPAPGRDPLTCDREGDGEPKSAHTSPEKKKAKELPEM DATSSRVWILTSTLTTSKVVIIDANQPGTVVDQFTVCNAHVLCISSIPAASDSDYPPGEMFLDSDVNPEDPGADGVLAGITLVGCATRCN VPRSNCSSRGDTPVLDKGQGEVATIANGKVNPSQSTEEATEATEVPDPGPSEPETATLRPGPLTEHVFTDPAPTPSSGPQPGSENGPEPD SSSTRPEPEPSGDPTGAGSSAAPTMWLGAQNGWLYVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGEDGQWDLSN YHLMDLGHPHHSIRCMAVVYDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVD IEPYVSKMLGTGKLGFSFVRITALLVAGSRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKTSPTSGEGARPGGIIHVYGDDSSDRAA SSFIPYCSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDSPAEGPGPAAPASEVEGQKLRNVLVLSGGEGYIDFRIGDGEDDETEE -------------------------------------------------------------- >19223_19223_4_CPT1A-MAPK8IP3_CPT1A_chr11_68579905_ENST00000376618_MAPK8IP3_chr16_1779139_ENST00000356010_length(transcript)=4321nt_BP=451nt GGACCCGCCTCAGCCAATCCGCTGCTGCCGGCGTCGGGTGCGCTCGGCCTCGCCCGCGGCCCTCCTTCCCCGGCTCCCGCTCGCCGCTCG TTCACTCCACCGCCGCCGCCGCCGCCGCCGCTGCCGCTGCCGCTGCCGCACCTCCGTAGCTGACTCGGTACTCTCTGAAGATGGCAGAAG CTCACCAAGCTGTGGCCTTTCAGTTCACGGTCACTCCGGACGGGATTGACCTGCGGCTGAGCCATGAAGCTCTTAGACAAATCTATCTCT CTGGACTTCATTCCTGGAAAAAGAAGTTCATCAGATTCAAGAACGGCATCATCACTGGCGTGTACCCGGCAAGCCCCTCCAGTTGGCTTA TCGTGGTGGTGGGCGTGATGACAACGATGTACGCCAAGATCGACCCCTCGTTAGGAATAATTGCAAAAATCAATCGGACTCTGGAAACGG CTTTCCCGGTTGGAGGAGCGGGAGTCGGAGATGAAGAAGGAGTACAATGCCCTGCACCAGCGGCACACAGAGATGATACAGACCTACGTG GAGCACATTGAGAGGTCCAAGATGCAGCAGGTCGGAGGAAACAGCCAGACCGAGAGCAGCCTGCCGGGGCGGAGGAAGGAGCGCCCCACC TCCCTGAACGTGTTCCCCCTGGCTGACGGCACGGTACGTGCACAGATCGGGGGCAAGCTCGTGCCTGCGGGGGACCACTGGCACCTGAGT GACCTCGGCCAGCTGCAGTCCAGCTCCAGCTACCAGTGTCCACAGGATGAAATGTCCGAGTCAGGCCAGTCCTCGGCGGCCGCCACACCC AGCACCACAGGCACCAAGTCCAACACGCCCACATCCTCCGTGCCCTCGGCCGCCGTCACACCCCTCAACGAGAGCCTGCAGCCCCTGGGG GACTATGGCGTGGGCTCCAAGAACAGCAAGCGTGCCCGGGAGAAGCGCGACAGCCGCAACATGGAAGTACAGGTCACCCAGGAGATGCGC AACGTCAGTATAGGCATGGGCAGCAGTGACGAGTGGTCTGATGTTCAAGACATTATTGACTCCACGCCAGAGCTGGACATGTGTCCAGAG ACCCGCCTGGACCGCACAGGAAGCAGCCCAACCCAGGGCATCGTGAACAAAGCTTTCGGCATCAACACCGACTCCCTGTACCATGAGCTG TCGACGGCAGGGTCTGAGGTCATCGGGGATGTGGACGAAGGGGCCGACCTCCTAGGGGAGTTCTCAGGAATGGGCAAAGAAGTGGGGAAT CTGCTACTGGAAAACTCACAGCTTCTGGAAACCAAAAACGCCTTGAATGTGGTGAAGAATGACCTGATTGCCAAGGTCGACCAGCTGTCC GGGGAGCAGGAGGTGCTGAGGGGCGAGTTGGAGGCTGCTAAGCAGGCCAAAGTCAAGCTGGAAAACCGTATCAAGGAGCTGGAAGAGGAA CTGAAAAGAGTGAAGTCCGAGGCCATCATCGCCCGCCGTGAACCCAAAGAAGAGGCGGAGGATGTAAGCAGCTATCTCTGTACAGAATCG GACAAAATCCCCATGGCCCAGCGCCGCCGCTTCACGCGGGTGGAGATGGCCCGTGTGCTCATGGAGCGGAACCAGTACAAGGAGCGGCTG ATGGAGCTGCAGGAGGCTGTGCGGTGGACTGAGATGATCAGAGCGTCCCGAGAGCACCCATCCGTCCAGGAGAAGAAGAAGTCGACCATC TGGCAGTTCTTCAGCCGCCTCTTCAGCTCTTCCTCCAGCCCCCCTCCGGCCAAGCGCCCCTATCCCTCGGTGAACATCCACTACAAGTCA CCCACCACTGCCGGCTTCAGCCAGCGCCGCAACCATGCCATGTGCCCGATCTCGGCAGGCAGCCGGCCCCTGGAATTCTTCCCTGACGAC GACTGCACGTCCTCCGCCCGTCGAGAGCAGAAGCGCGAGCAGTACCGCCAGGTGCGTGAGCACGTGCGTAACGACGACGGCCGTCTGCAG GCCTGCGGCTGGAGCCTGCCCGCCAAGTACAAGCAGCTGAGTCCCAACGGGGGCCAGGAGGACACGCGGATGAAGAACGTGCCGGTGCCG GTGTACTGCCGCCCTCTGGTGGAGAAGGACCCCACCATGAAGCTGTGGTGTGCCGCGGGCGTCAACCTGAGCGGGTGGAGGCCCAATGAG GACGACGCTGGGAATGGAGTCAAGCCAGCGCCAGGCCGCGATCCCCTGACCTGCGACCGCGAAGGAGACGGCGAGCCCAAGAGCGCCCAC ACGTCTCCCGAGAAGAAGAAGGCCAAGGAGCTCCCTGAAATGGACGCCACCTCCAGCCGGGTGTGGATCCTGACCAGCACCCTGACCACC AGCAAGGTGGTGATCATCGACGCCAACCAGCCGGGCACGGTGGTGGACCAGTTCACCGTCTGCAACGCGCACGTGCTGTGCATCTCCAGC ATCCCCGCGGCCAGCGACAGCGACTACCCTCCCGGGGAGATGTTCCTGGACAGCGACGTGAACCCAGAGGACCCGGGCGCAGATGGCGTG CTGGCCGGTATCACCCTGGTGGGCTGTGCCACCCGCTGCAACGTGCCGCGGAGCAACTGCTCCTCCCGAGGGGACACCCCAGTGCTAGAC AAGGGGCAGGGGGAGGTGGCCACCATCGCCAACGGGAAGGTCAACCCGTCCCAGTCCACAGAGGAGGCCACAGAGGCCACGGAGGTGCCA GACCCTGGGCCCAGCGAGCCAGAGACAGCCACATTGCGGCCCGGGCCTCTCACAGAGCACGTCTTCACTGACCCAGCCCCGACCCCGTCC TCTGGCCCCCAGCCTGGCAGCGAGAACGGGCCAGAGCCTGACAGCAGCAGCACACGGCCAGAGCCAGAGCCCAGCGGGGACCCCACGGGA GCAGGCAGCAGTGCTGCACCCACCATGTGGCTGGGAGCCCAGAACGGCTGGCTCTATGTGCACTCGGCTGTGGCCAACTGGAAGAAGTGC CTGCACTCCATCAAGCTGAAGGATTCTGTGCTGAGCCTGGTGCATGTCAAAGGCCGTGTGCTGGTGGCTCTGGCGGACGGGACCCTGGCC ATCTTCCACCGTGGTGAAGATGGCCAGTGGGATCTGAGCAACTATCACCTAATGGACCTGGGCCACCCGCACCACTCCATCCGCTGCATG GCTGTTGTGTACGACCGCGTGTGGTGTGGCTACAAGAACAAGGTGCACGTCATCCAGCCCAAGACCATGCAGATAGAGAAGTCATTTGAC GCCCACCCGCGGCGGGAGAGCCAGGTGCGGCAGCTGGCGTGGATCGGCGATGGCGTATGGGTGTCCATCCGCCTGGACTCCACCCTGAGG CTCTACCATGCACACACGCACCAGCATCTACAGGACGTGGACATTGAGCCCTACGTCAGCAAGATGCTAGGCACTGGCAAGCTGGGTTTC TCCTTCGTACGCATCACGGCCCTGCTTGTCGCGGGCAGCCGGCTCTGGGTGGGCACCGGCAACGGAGTGGTCATCTCCATCCCCCTGACA GAGACTGTGGTCCTGCACCGAGGCCAGCTCCTGGGGCTCCGAGCCAATAAGACATCCCCCACCTCTGGGGAGGGCGCCCGTCCCGGGGGC ATCATCCACGTGTATGGCGATGACAGCAGTGACAGGGCGGCCAGCAGCTTCATCCCCTACTGCTCCATGGCCCAGGCCCAGCTATGCTTC CATGGGCACCGCGATGCCGTGAAGTTCTTTGTCTCGGTGCCAGGGAACGTGCTGGCCACCCTGAATGGGAGTGTGCTGGACAGCCCAGCC GAGGGCCCTGGGCCAGCTGCCCCTGCCTCGGAGGTCGAGGGCCAGAAGCTGCGGAACGTGCTGGTGCTGAGCGGCGGGGAGGGCTACATC GACTTCCGCATTGGAGACGGAGAGGACGACGAGACGGAGGAGGGCGCAGGGGACATGAGCCAGGTGAAGCCCGTGCTGTCCAAGGCAGAG CGCAGTCACATCATCGTGTGGCAGGTGTCCTACACCCCCGAGTGAAGCTGCTGCCCTGCCTGGCCCGACCTGTACATAGGACCCCCGACC ACCTGACCCCCGCCCGGCCCGCGGGGTAGCCAGCCAGGCGCCGCCGCCCCTCTTCTAACCTCTCAACCTGCAGCTTTCACCTGAGTCTGG CCCCTCCAGCGGGCAGGGAGTGCGGGGATGCGGATCAGCTGGGAGGAGGAGGGGAGGGGAACTTCCACCCGAGGGGAAGATGCTCTCGGG ACAGTTTCCCGGGCAGCTCCTGGCCAGCTTCCAGCCCAGAGTCCTCAAGTCCAGGGCACCTTGGGCCCAGCGCAGGCAGAATCCGAGGTG >19223_19223_4_CPT1A-MAPK8IP3_CPT1A_chr11_68579905_ENST00000376618_MAPK8IP3_chr16_1779139_ENST00000356010_length(amino acids)=1194AA_BP=11 MQKSIGLWKRLSRLEERESEMKKEYNALHQRHTEMIQTYVEHIERSKMQQVGGNSQTESSLPGRRKERPTSLNVFPLADGTVRAQIGGKL VPAGDHWHLSDLGQLQSSSSYQCPQDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQPLGDYGVGSKNSKRAREKRDSRN MEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDMCPETRLDRTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGE FSGMGKEVGNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLRGELEAAKQAKVKLENRIKELEEELKRVKSEAIIARREPKEEAE DVSSYLCTESDKIPMAQRRRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASREHPSVQEKKKSTIWQFFSRLFSSSSSPPPAKRP YPSVNIHYKSPTTAGFSQRRNHAMCPISAGSRPLEFFPDDDCTSSARREQKREQYRQVREHVRNDDGRLQACGWSLPAKYKQLSPNGGQE DTRMKNVPVPVYCRPLVEKDPTMKLWCAAGVNLSGWRPNEDDAGNGVKPAPGRDPLTCDREGDGEPKSAHTSPEKKKAKELPEMDATSSR VWILTSTLTTSKVVIIDANQPGTVVDQFTVCNAHVLCISSIPAASDSDYPPGEMFLDSDVNPEDPGADGVLAGITLVGCATRCNVPRSNC SSRGDTPVLDKGQGEVATIANGKVNPSQSTEEATEATEVPDPGPSEPETATLRPGPLTEHVFTDPAPTPSSGPQPGSENGPEPDSSSTRP EPEPSGDPTGAGSSAAPTMWLGAQNGWLYVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGEDGQWDLSNYHLMDL GHPHHSIRCMAVVYDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVS KMLGTGKLGFSFVRITALLVAGSRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKTSPTSGEGARPGGIIHVYGDDSSDRAASSFIPY CSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDSPAEGPGPAAPASEVEGQKLRNVLVLSGGEGYIDFRIGDGEDDETEEGAGDMS -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for CPT1A-MAPK8IP3 |
Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
- Retained PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
Tgene | MAPK8IP3 | chr11:68579905 | chr16:1779139 | ENST00000250894 | 1 | 32 | 458_514 | 146.33333333333334 | 1337.0 | NTRK2 |
- Lost PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
- Retained PPIs, but lost function due to frame-shift fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for CPT1A-MAPK8IP3 |
Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for CPT1A-MAPK8IP3 |
Diseases associated with fusion partners. (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | CPT1A | C1829703 | Carnitine palmitoyl transferase 1A deficiency | 13 | CLINGEN;CTD_human;GENOMICS_ENGLAND;UNIPROT |
Hgene | CPT1A | C0002152 | Alloxan Diabetes | 1 | CTD_human |
Hgene | CPT1A | C0006142 | Malignant neoplasm of breast | 1 | CTD_human |
Hgene | CPT1A | C0011849 | Diabetes Mellitus | 1 | CTD_human |
Hgene | CPT1A | C0011853 | Diabetes Mellitus, Experimental | 1 | CTD_human |
Hgene | CPT1A | C0011860 | Diabetes Mellitus, Non-Insulin-Dependent | 1 | CTD_human |
Hgene | CPT1A | C0022661 | Kidney Failure, Chronic | 1 | CTD_human |
Hgene | CPT1A | C0038433 | Streptozotocin Diabetes | 1 | CTD_human |
Hgene | CPT1A | C0400966 | Non-alcoholic Fatty Liver Disease | 1 | CTD_human |
Hgene | CPT1A | C0678222 | Breast Carcinoma | 1 | CTD_human |
Hgene | CPT1A | C1257931 | Mammary Neoplasms, Human | 1 | CTD_human |
Hgene | CPT1A | C1458155 | Mammary Neoplasms | 1 | CTD_human |
Hgene | CPT1A | C3241937 | Nonalcoholic Steatohepatitis | 1 | CTD_human |
Hgene | CPT1A | C4704874 | Mammary Carcinoma, Human | 1 | CTD_human |
Tgene | C0032460 | Polycystic Ovary Syndrome | 1 | CTD_human | |
Tgene | C0557874 | Global developmental delay | 1 | GENOMICS_ENGLAND | |
Tgene | C0852413 | Abnormal muscle tone | 1 | GENOMICS_ENGLAND | |
Tgene | C1136382 | Sclerocystic Ovaries | 1 | CTD_human | |
Tgene | C3714756 | Intellectual Disability | 1 | GENOMICS_ENGLAND | |
Tgene | C4022810 | Abnormality of nervous system morphology | 1 | GENOMICS_ENGLAND |