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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CSNK1D-CCDC57 (FusionGDB2 ID:HG1453TG284001)

Fusion Gene Summary for CSNK1D-CCDC57

check button Fusion gene summary
Fusion gene informationFusion gene name: CSNK1D-CCDC57
Fusion gene ID: hg1453tg284001
HgeneTgene
Gene symbol

CSNK1D

CCDC57

Gene ID

1453

284001

Gene namecasein kinase 1 deltacoiled-coil domain containing 57
SynonymsASPS|CKI-delta|CKId|CKIdelta|FASPS2|HCKID-
Cytomap('CSNK1D')('CCDC57')

17q25.3

17q25.3

Type of geneprotein-codingprotein-coding
Descriptioncasein kinase I isoform deltacasein kinase Itau-protein kinase CSNK1Dcoiled-coil domain-containing protein 57
Modification date2020031320200313
UniProtAcc.

Q2TAC2

Ensembl transtripts involved in fusion geneENST00000314028, ENST00000392334, 
ENST00000398519, ENST00000578904, 
ENST00000578904, ENST00000314028, 
ENST00000392334, ENST00000398519, 
Fusion gene scores* DoF score17 X 16 X 13=353619 X 12 X 13=2964
# samples 2422
** MAII scorelog2(24/3536*10)=-3.88101196378291
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(22/2964*10)=-3.75197001878117
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CSNK1D [Title/Abstract] AND CCDC57 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCSNK1D(80209254)-CCDC57(80059742), # samples:1
CSNK1D(80209255)-CCDC57(80059742), # samples:1
Anticipated loss of major functional domain due to fusion event.CCDC57-CSNK1D seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CCDC57-CSNK1D seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CSNK1D-CCDC57 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CSNK1D-CCDC57 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CSNK1D-CCDC57 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CSNK1D-CCDC57 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CCDC57-CSNK1D seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
CCDC57-CSNK1D seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
CCDC57-CSNK1D seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
CSNK1D-CCDC57 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CSNK1D-CCDC57 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
CSNK1D-CCDC57 seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCSNK1D

GO:0006468

protein phosphorylation

16618118

HgeneCSNK1D

GO:0018105

peptidyl-serine phosphorylation

25500533

HgeneCSNK1D

GO:0051225

spindle assembly

10826492


check buttonFusion gene breakpoints across CSNK1D (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CCDC57 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-95-7944-01ACSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
ChimerDB4LUADTCGA-95-7944CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-


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Fusion Gene ORF analysis for CSNK1D-CCDC57

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000314028ENST00000327026CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
5CDS-intronENST00000314028ENST00000327026CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
5CDS-intronENST00000314028ENST00000392343CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
5CDS-intronENST00000314028ENST00000392343CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
5CDS-intronENST00000314028ENST00000392346CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
5CDS-intronENST00000314028ENST00000392346CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
5CDS-intronENST00000392334ENST00000327026CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
5CDS-intronENST00000392334ENST00000327026CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
5CDS-intronENST00000392334ENST00000392343CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
5CDS-intronENST00000392334ENST00000392343CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
5CDS-intronENST00000392334ENST00000392346CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
5CDS-intronENST00000392334ENST00000392346CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
5CDS-intronENST00000398519ENST00000327026CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
5CDS-intronENST00000398519ENST00000327026CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
5CDS-intronENST00000398519ENST00000392343CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
5CDS-intronENST00000398519ENST00000392343CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
5CDS-intronENST00000398519ENST00000392346CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
5CDS-intronENST00000398519ENST00000392346CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
5UTR-3CDSENST00000578904ENST00000389641CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
5UTR-3CDSENST00000578904ENST00000389641CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
5UTR-3CDSENST00000578904ENST00000392347CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
5UTR-3CDSENST00000578904ENST00000392347CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
5UTR-intronENST00000578904ENST00000327026CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
5UTR-intronENST00000578904ENST00000327026CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
5UTR-intronENST00000578904ENST00000392343CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
5UTR-intronENST00000578904ENST00000392343CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
5UTR-intronENST00000578904ENST00000392346CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
5UTR-intronENST00000578904ENST00000392346CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
Frame-shiftENST00000392334ENST00000389641CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
Frame-shiftENST00000392334ENST00000389641CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
Frame-shiftENST00000392334ENST00000392347CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
Frame-shiftENST00000392334ENST00000392347CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
In-frameENST00000314028ENST00000389641CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
In-frameENST00000314028ENST00000389641CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
In-frameENST00000314028ENST00000392347CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
In-frameENST00000314028ENST00000392347CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
In-frameENST00000398519ENST00000389641CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
In-frameENST00000398519ENST00000389641CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-
In-frameENST00000398519ENST00000392347CSNK1Dchr17

80209255

-CCDC57chr17

80059742

-
In-frameENST00000398519ENST00000392347CSNK1Dchr17

80209254

-CCDC57chr17

80059742

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000398519CSNK1Dchr1780209254-ENST00000392347CCDC57chr1780059742-1329932471003318
ENST00000398519CSNK1Dchr1780209254-ENST00000389641CCDC57chr1780059742-1329932471003318
ENST00000314028CSNK1Dchr1780209254-ENST00000392347CCDC57chr1780059742-16321235111306431
ENST00000314028CSNK1Dchr1780209254-ENST00000389641CCDC57chr1780059742-16321235111306431
ENST00000398519CSNK1Dchr1780209255-ENST00000392347CCDC57chr1780059742-1329932471003318
ENST00000398519CSNK1Dchr1780209255-ENST00000389641CCDC57chr1780059742-1329932471003318
ENST00000314028CSNK1Dchr1780209255-ENST00000392347CCDC57chr1780059742-16321235111306431
ENST00000314028CSNK1Dchr1780209255-ENST00000389641CCDC57chr1780059742-16321235111306431

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000398519ENST00000392347CSNK1Dchr1780209254-CCDC57chr1780059742-0.0067939240.99320614
ENST00000398519ENST00000389641CSNK1Dchr1780209254-CCDC57chr1780059742-0.0067939240.99320614
ENST00000314028ENST00000392347CSNK1Dchr1780209254-CCDC57chr1780059742-0.0092392910.9907607
ENST00000314028ENST00000389641CSNK1Dchr1780209254-CCDC57chr1780059742-0.0092392910.9907607
ENST00000398519ENST00000392347CSNK1Dchr1780209255-CCDC57chr1780059742-0.0067939240.99320614
ENST00000398519ENST00000389641CSNK1Dchr1780209255-CCDC57chr1780059742-0.0067939240.99320614
ENST00000314028ENST00000392347CSNK1Dchr1780209255-CCDC57chr1780059742-0.0092392910.9907607
ENST00000314028ENST00000389641CSNK1Dchr1780209255-CCDC57chr1780059742-0.0092392910.9907607

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Fusion Genomic Features for CSNK1D-CCDC57


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for CSNK1D-CCDC57


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:80209254/chr17:80059742)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CCDC57

Q2TAC2

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Pleiotropic regulator of centriole duplication, mitosis, and ciliogenesis. Critical interface between centrosome and microtubule-mediated cellular processes. Centriole duplication protein required for recruitment of CEP63, CEP152, and PLK4 to the centrosome. Independent of its centrosomal targeting, localizes to and interacts with microtubules and regulates microtubule nucleation, stability, and mitotic progression. {ECO:0000269|PubMed:32402286}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCSNK1Dchr17:80209254chr17:80059742ENST00000314028-699_277295416.0DomainProtein kinase
HgeneCSNK1Dchr17:80209254chr17:80059742ENST00000392334-6109_277295420.3333333333333DomainProtein kinase
HgeneCSNK1Dchr17:80209255chr17:80059742ENST00000314028-699_277295416.0DomainProtein kinase
HgeneCSNK1Dchr17:80209255chr17:80059742ENST00000392334-6109_277295420.3333333333333DomainProtein kinase
HgeneCSNK1Dchr17:80209254chr17:80059742ENST00000314028-6915_23295416.0Nucleotide bindingATP
HgeneCSNK1Dchr17:80209254chr17:80059742ENST00000392334-61015_23295420.3333333333333Nucleotide bindingATP
HgeneCSNK1Dchr17:80209255chr17:80059742ENST00000314028-6915_23295416.0Nucleotide bindingATP
HgeneCSNK1Dchr17:80209255chr17:80059742ENST00000392334-61015_23295420.3333333333333Nucleotide bindingATP
TgeneCCDC57chr17:80209254chr17:80059742ENST00000392343015214_4220752.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209254chr17:80059742ENST00000392343015456_4830752.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209254chr17:80059742ENST00000392343015521_5480752.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209254chr17:80059742ENST0000039234301592_1730752.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209255chr17:80059742ENST00000392343015214_4220752.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209255chr17:80059742ENST00000392343015456_4830752.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209255chr17:80059742ENST00000392343015521_5480752.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209255chr17:80059742ENST0000039234301592_1730752.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209254chr17:80059742ENST000003923430151_5020752.0RegionCentrosomal targeting domain
TgeneCCDC57chr17:80209254chr17:80059742ENST00000392343015606_9150752.0RegionMicrotubule binding domain
TgeneCCDC57chr17:80209255chr17:80059742ENST000003923430151_5020752.0RegionCentrosomal targeting domain
TgeneCCDC57chr17:80209255chr17:80059742ENST00000392343015606_9150752.0RegionMicrotubule binding domain

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCSNK1Dchr17:80209254chr17:80059742ENST00000314028-69278_364295416.0RegionNote=Centrosomal localization signal (CLS)
HgeneCSNK1Dchr17:80209254chr17:80059742ENST00000314028-69317_342295416.0RegionAutoinhibitory
HgeneCSNK1Dchr17:80209254chr17:80059742ENST00000392334-610278_364295420.3333333333333RegionNote=Centrosomal localization signal (CLS)
HgeneCSNK1Dchr17:80209254chr17:80059742ENST00000392334-610317_342295420.3333333333333RegionAutoinhibitory
HgeneCSNK1Dchr17:80209255chr17:80059742ENST00000314028-69278_364295416.0RegionNote=Centrosomal localization signal (CLS)
HgeneCSNK1Dchr17:80209255chr17:80059742ENST00000314028-69317_342295416.0RegionAutoinhibitory
HgeneCSNK1Dchr17:80209255chr17:80059742ENST00000392334-610278_364295420.3333333333333RegionNote=Centrosomal localization signal (CLS)
HgeneCSNK1Dchr17:80209255chr17:80059742ENST00000392334-610317_342295420.3333333333333RegionAutoinhibitory
TgeneCCDC57chr17:80209254chr17:80059742ENST000003896411618214_422855917.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209254chr17:80059742ENST000003896411618456_483855917.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209254chr17:80059742ENST000003896411618521_548855917.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209254chr17:80059742ENST00000389641161892_173855917.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209254chr17:80059742ENST000003923471517214_422855917.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209254chr17:80059742ENST000003923471517456_483855917.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209254chr17:80059742ENST000003923471517521_548855917.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209254chr17:80059742ENST00000392347151792_173855917.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209255chr17:80059742ENST000003896411618214_422855917.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209255chr17:80059742ENST000003896411618456_483855917.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209255chr17:80059742ENST000003896411618521_548855917.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209255chr17:80059742ENST00000389641161892_173855917.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209255chr17:80059742ENST000003923471517214_422855917.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209255chr17:80059742ENST000003923471517456_483855917.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209255chr17:80059742ENST000003923471517521_548855917.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209255chr17:80059742ENST00000392347151792_173855917.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC57chr17:80209254chr17:80059742ENST0000038964116181_502855917.0RegionCentrosomal targeting domain
TgeneCCDC57chr17:80209254chr17:80059742ENST000003896411618606_915855917.0RegionMicrotubule binding domain
TgeneCCDC57chr17:80209254chr17:80059742ENST0000039234715171_502855917.0RegionCentrosomal targeting domain
TgeneCCDC57chr17:80209254chr17:80059742ENST000003923471517606_915855917.0RegionMicrotubule binding domain
TgeneCCDC57chr17:80209255chr17:80059742ENST0000038964116181_502855917.0RegionCentrosomal targeting domain
TgeneCCDC57chr17:80209255chr17:80059742ENST000003896411618606_915855917.0RegionMicrotubule binding domain
TgeneCCDC57chr17:80209255chr17:80059742ENST0000039234715171_502855917.0RegionCentrosomal targeting domain
TgeneCCDC57chr17:80209255chr17:80059742ENST000003923471517606_915855917.0RegionMicrotubule binding domain


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Fusion Gene Sequence for CSNK1D-CCDC57


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>19815_19815_1_CSNK1D-CCDC57_CSNK1D_chr17_80209254_ENST00000314028_CCDC57_chr17_80059742_ENST00000389641_length(transcript)=1632nt_BP=1235nt
GCCCCGCCGGGTTGCTAGGGGAAGTGACGTCACAGCGCGATGGCGGCGGCTCCTTTAGGCAGCTGAAAGGGGATTTAGGCCCGGAAGATC
CGAGTCCATCCGCGGCGGGGAGAGGGCAAGCGGGACCGGTAGGGGCCGGAGCAGCGGCGGCGGCGCTCGGACTGTCCCATCCGCCCCGTA
TTGAGGCGCTGGGAGCGGCGGGGCGACAGGAAAGCGATGGTGAAAGCGGGGCCGTGAGGGGGGCGGAGCCGGGAGCCGGACCCGCAGTAG
CGGCAGCAGCGGCGCCGCCTCCCAGAGTTCAGACCCAGGAAGCGGCCGGGAGGGCAGGAGCGAATCGGGCCGCCGCCGCCATGGAGCTGA
GAGTCGGGAACAGGTACCGGCTGGGCCGGAAGATCGGCAGCGGCTCCTTCGGAGACATCTATCTCGGTACGGACATTGCTGCAGGAGAAG
AGGTTGCCATCAAGCTTGAATGTGTCAAAACCAAACACCCTCAGCTCCACATTGAGAGCAAAATCTACAAGATGATGCAGGGAGGAGTGG
GCATCCCCACCATCAGATGGTGCGGGGCAGAGGGGGACTACAACGTCATGGTGATGGAGCTGCTGGGGCCAAGCCTGGAGGACCTCTTCA
ACTTCTGCTCCAGGAAATTCAGCCTCAAAACCGTCCTGCTGCTTGCTGACCAAATGATCAGTCGCATCGAATACATTCATTCAAAGAACT
TCATCCACCGGGATGTGAAGCCAGACAACTTCCTCATGGGCCTGGGGAAGAAGGGCAACCTGGTGTACATCATCGACTTCGGGCTGGCCA
AGAAGTACCGGGATGCACGCACCCACCAGCACATCCCCTATCGTGAGAACAAGAACCTCACGGGGACGGCGCGGTACGCCTCCATCAACA
CGCACCTTGGAATTGAACAATCCCGAAGAGATGACTTGGAGTCTCTGGGCTACGTGCTAATGTACTTCAACCTGGGCTCTCTCCCCTGGC
AGGGGCTGAAGGCTGCCACCAAGAGACAGAAATACGAAAGGATTAGCGAGAAGAAAATGTCCACCCCCATCGAAGTGTTGTGTAAAGGCT
ACCCTTCCGAATTTGCCACATACCTGAATTTCTGCCGTTCCTTGCGTTTTGACGACAAGCCTGACTACTCGTACCTGCGGCAGCTTTTCC
GGAATCTGTTCCATCGCCAGGGCTTCTCCTATGACTACGTGTTCGACTGGAACATGCTCAAATTTAGCTCCCAGCTCCTCCAGCAGCCGA
CAGGAGGCCCGTCAAGATGCAGGCAGGCATTGCCACCCCAGGGATGAAGACAGCAGCCCAGGCAAAGGCCAAGACCACAGGAGCCTCCCG
GTCTCATCCTGCAAAAGCTAAAGGCTGCCAGAGGCCCCCCAAGATCCGTAACTACAACATTATGGACTGACTTCCTCCCCCCACCCCGCC
CCACTAAGGGGTGCTCGGGGCCTCCGCATGGTGCCTGTGCTTTCACCTACGTGTTGTGGGGGGGTGTGGGCACAGCGTGCAGGGTGGAGG
CAGGGAGCTGCAGGGCAGGCTCCCAAATGCTGCTGAGGCGACCCTGCTGACTGAAGGCCTCCCTGAGCACAGGGCCCATTAAAACCAGGT

>19815_19815_1_CSNK1D-CCDC57_CSNK1D_chr17_80209254_ENST00000314028_CCDC57_chr17_80059742_ENST00000389641_length(amino acids)=431AA_BP=28
MLGEVTSQRDGGGSFRQLKGDLGPEDPSPSAAGRGQAGPVGAGAAAAALGLSHPPRIEALGAAGRQESDGESGAVRGAEPGAGPAVAAAA
APPPRVQTQEAAGRAGANRAAAAMELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPT
IRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYR
DARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSE

--------------------------------------------------------------
>19815_19815_2_CSNK1D-CCDC57_CSNK1D_chr17_80209254_ENST00000314028_CCDC57_chr17_80059742_ENST00000392347_length(transcript)=1632nt_BP=1235nt
GCCCCGCCGGGTTGCTAGGGGAAGTGACGTCACAGCGCGATGGCGGCGGCTCCTTTAGGCAGCTGAAAGGGGATTTAGGCCCGGAAGATC
CGAGTCCATCCGCGGCGGGGAGAGGGCAAGCGGGACCGGTAGGGGCCGGAGCAGCGGCGGCGGCGCTCGGACTGTCCCATCCGCCCCGTA
TTGAGGCGCTGGGAGCGGCGGGGCGACAGGAAAGCGATGGTGAAAGCGGGGCCGTGAGGGGGGCGGAGCCGGGAGCCGGACCCGCAGTAG
CGGCAGCAGCGGCGCCGCCTCCCAGAGTTCAGACCCAGGAAGCGGCCGGGAGGGCAGGAGCGAATCGGGCCGCCGCCGCCATGGAGCTGA
GAGTCGGGAACAGGTACCGGCTGGGCCGGAAGATCGGCAGCGGCTCCTTCGGAGACATCTATCTCGGTACGGACATTGCTGCAGGAGAAG
AGGTTGCCATCAAGCTTGAATGTGTCAAAACCAAACACCCTCAGCTCCACATTGAGAGCAAAATCTACAAGATGATGCAGGGAGGAGTGG
GCATCCCCACCATCAGATGGTGCGGGGCAGAGGGGGACTACAACGTCATGGTGATGGAGCTGCTGGGGCCAAGCCTGGAGGACCTCTTCA
ACTTCTGCTCCAGGAAATTCAGCCTCAAAACCGTCCTGCTGCTTGCTGACCAAATGATCAGTCGCATCGAATACATTCATTCAAAGAACT
TCATCCACCGGGATGTGAAGCCAGACAACTTCCTCATGGGCCTGGGGAAGAAGGGCAACCTGGTGTACATCATCGACTTCGGGCTGGCCA
AGAAGTACCGGGATGCACGCACCCACCAGCACATCCCCTATCGTGAGAACAAGAACCTCACGGGGACGGCGCGGTACGCCTCCATCAACA
CGCACCTTGGAATTGAACAATCCCGAAGAGATGACTTGGAGTCTCTGGGCTACGTGCTAATGTACTTCAACCTGGGCTCTCTCCCCTGGC
AGGGGCTGAAGGCTGCCACCAAGAGACAGAAATACGAAAGGATTAGCGAGAAGAAAATGTCCACCCCCATCGAAGTGTTGTGTAAAGGCT
ACCCTTCCGAATTTGCCACATACCTGAATTTCTGCCGTTCCTTGCGTTTTGACGACAAGCCTGACTACTCGTACCTGCGGCAGCTTTTCC
GGAATCTGTTCCATCGCCAGGGCTTCTCCTATGACTACGTGTTCGACTGGAACATGCTCAAATTTAGCTCCCAGCTCCTCCAGCAGCCGA
CAGGAGGCCCGTCAAGATGCAGGCAGGCATTGCCACCCCAGGGATGAAGACAGCAGCCCAGGCAAAGGCCAAGACCACAGGAGCCTCCCG
GTCTCATCCTGCAAAAGCTAAAGGCTGCCAGAGGCCCCCCAAGATCCGTAACTACAACATTATGGACTGACTTCCTCCCCCCACCCCGCC
CCACTAAGGGGTGCTCGGGGCCTCCGCATGGTGCCTGTGCTTTCACCTACGTGTTGTGGGGGGGTGTGGGCACAGCGTGCAGGGTGGAGG
CAGGGAGCTGCAGGGCAGGCTCCCAAATGCTGCTGAGGCGACCCTGCTGACTGAAGGCCTCCCTGAGCACAGGGCCCATTAAAACCAGGT

>19815_19815_2_CSNK1D-CCDC57_CSNK1D_chr17_80209254_ENST00000314028_CCDC57_chr17_80059742_ENST00000392347_length(amino acids)=431AA_BP=28
MLGEVTSQRDGGGSFRQLKGDLGPEDPSPSAAGRGQAGPVGAGAAAAALGLSHPPRIEALGAAGRQESDGESGAVRGAEPGAGPAVAAAA
APPPRVQTQEAAGRAGANRAAAAMELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPT
IRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYR
DARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSE

--------------------------------------------------------------
>19815_19815_3_CSNK1D-CCDC57_CSNK1D_chr17_80209254_ENST00000398519_CCDC57_chr17_80059742_ENST00000389641_length(transcript)=1329nt_BP=932nt
CCCAGGAAGCGGCCGGGAGGGCAGGAGCGAATCGGGCCGCCGCCGCCATGGAGCTGAGAGTCGGGAACAGGTACCGGCTGGGCCGGAAGA
TCGGCAGCGGCTCCTTCGGAGACATCTATCTCGGTACGGACATTGCTGCAGGAGAAGAGGTTGCCATCAAGCTTGAATGTGTCAAAACCA
AACACCCTCAGCTCCACATTGAGAGCAAAATCTACAAGATGATGCAGGGAGGAGTGGGCATCCCCACCATCAGATGGTGCGGGGCAGAGG
GGGACTACAACGTCATGGTGATGGAGCTGCTGGGGCCAAGCCTGGAGGACCTCTTCAACTTCTGCTCCAGGAAATTCAGCCTCAAAACCG
TCCTGCTGCTTGCTGACCAAATGATCAGTCGCATCGAATACATTCATTCAAAGAACTTCATCCACCGGGATGTGAAGCCAGACAACTTCC
TCATGGGCCTGGGGAAGAAGGGCAACCTGGTGTACATCATCGACTTCGGGCTGGCCAAGAAGTACCGGGATGCACGCACCCACCAGCACA
TCCCCTATCGTGAGAACAAGAACCTCACGGGGACGGCGCGGTACGCCTCCATCAACACGCACCTTGGAATTGAACAATCCCGAAGAGATG
ACTTGGAGTCTCTGGGCTACGTGCTAATGTACTTCAACCTGGGCTCTCTCCCCTGGCAGGGGCTGAAGGCTGCCACCAAGAGACAGAAAT
ACGAAAGGATTAGCGAGAAGAAAATGTCCACCCCCATCGAAGTGTTGTGTAAAGGCTACCCTTCCGAATTTGCCACATACCTGAATTTCT
GCCGTTCCTTGCGTTTTGACGACAAGCCTGACTACTCGTACCTGCGGCAGCTTTTCCGGAATCTGTTCCATCGCCAGGGCTTCTCCTATG
ACTACGTGTTCGACTGGAACATGCTCAAATTTAGCTCCCAGCTCCTCCAGCAGCCGACAGGAGGCCCGTCAAGATGCAGGCAGGCATTGC
CACCCCAGGGATGAAGACAGCAGCCCAGGCAAAGGCCAAGACCACAGGAGCCTCCCGGTCTCATCCTGCAAAAGCTAAAGGCTGCCAGAG
GCCCCCCAAGATCCGTAACTACAACATTATGGACTGACTTCCTCCCCCCACCCCGCCCCACTAAGGGGTGCTCGGGGCCTCCGCATGGTG
CCTGTGCTTTCACCTACGTGTTGTGGGGGGGTGTGGGCACAGCGTGCAGGGTGGAGGCAGGGAGCTGCAGGGCAGGCTCCCAAATGCTGC

>19815_19815_3_CSNK1D-CCDC57_CSNK1D_chr17_80209254_ENST00000398519_CCDC57_chr17_80059742_ENST00000389641_length(amino acids)=318AA_BP=0
MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLE
DLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLR

--------------------------------------------------------------
>19815_19815_4_CSNK1D-CCDC57_CSNK1D_chr17_80209254_ENST00000398519_CCDC57_chr17_80059742_ENST00000392347_length(transcript)=1329nt_BP=932nt
CCCAGGAAGCGGCCGGGAGGGCAGGAGCGAATCGGGCCGCCGCCGCCATGGAGCTGAGAGTCGGGAACAGGTACCGGCTGGGCCGGAAGA
TCGGCAGCGGCTCCTTCGGAGACATCTATCTCGGTACGGACATTGCTGCAGGAGAAGAGGTTGCCATCAAGCTTGAATGTGTCAAAACCA
AACACCCTCAGCTCCACATTGAGAGCAAAATCTACAAGATGATGCAGGGAGGAGTGGGCATCCCCACCATCAGATGGTGCGGGGCAGAGG
GGGACTACAACGTCATGGTGATGGAGCTGCTGGGGCCAAGCCTGGAGGACCTCTTCAACTTCTGCTCCAGGAAATTCAGCCTCAAAACCG
TCCTGCTGCTTGCTGACCAAATGATCAGTCGCATCGAATACATTCATTCAAAGAACTTCATCCACCGGGATGTGAAGCCAGACAACTTCC
TCATGGGCCTGGGGAAGAAGGGCAACCTGGTGTACATCATCGACTTCGGGCTGGCCAAGAAGTACCGGGATGCACGCACCCACCAGCACA
TCCCCTATCGTGAGAACAAGAACCTCACGGGGACGGCGCGGTACGCCTCCATCAACACGCACCTTGGAATTGAACAATCCCGAAGAGATG
ACTTGGAGTCTCTGGGCTACGTGCTAATGTACTTCAACCTGGGCTCTCTCCCCTGGCAGGGGCTGAAGGCTGCCACCAAGAGACAGAAAT
ACGAAAGGATTAGCGAGAAGAAAATGTCCACCCCCATCGAAGTGTTGTGTAAAGGCTACCCTTCCGAATTTGCCACATACCTGAATTTCT
GCCGTTCCTTGCGTTTTGACGACAAGCCTGACTACTCGTACCTGCGGCAGCTTTTCCGGAATCTGTTCCATCGCCAGGGCTTCTCCTATG
ACTACGTGTTCGACTGGAACATGCTCAAATTTAGCTCCCAGCTCCTCCAGCAGCCGACAGGAGGCCCGTCAAGATGCAGGCAGGCATTGC
CACCCCAGGGATGAAGACAGCAGCCCAGGCAAAGGCCAAGACCACAGGAGCCTCCCGGTCTCATCCTGCAAAAGCTAAAGGCTGCCAGAG
GCCCCCCAAGATCCGTAACTACAACATTATGGACTGACTTCCTCCCCCCACCCCGCCCCACTAAGGGGTGCTCGGGGCCTCCGCATGGTG
CCTGTGCTTTCACCTACGTGTTGTGGGGGGGTGTGGGCACAGCGTGCAGGGTGGAGGCAGGGAGCTGCAGGGCAGGCTCCCAAATGCTGC

>19815_19815_4_CSNK1D-CCDC57_CSNK1D_chr17_80209254_ENST00000398519_CCDC57_chr17_80059742_ENST00000392347_length(amino acids)=318AA_BP=0
MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLE
DLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLR

--------------------------------------------------------------
>19815_19815_5_CSNK1D-CCDC57_CSNK1D_chr17_80209255_ENST00000314028_CCDC57_chr17_80059742_ENST00000389641_length(transcript)=1632nt_BP=1235nt
GCCCCGCCGGGTTGCTAGGGGAAGTGACGTCACAGCGCGATGGCGGCGGCTCCTTTAGGCAGCTGAAAGGGGATTTAGGCCCGGAAGATC
CGAGTCCATCCGCGGCGGGGAGAGGGCAAGCGGGACCGGTAGGGGCCGGAGCAGCGGCGGCGGCGCTCGGACTGTCCCATCCGCCCCGTA
TTGAGGCGCTGGGAGCGGCGGGGCGACAGGAAAGCGATGGTGAAAGCGGGGCCGTGAGGGGGGCGGAGCCGGGAGCCGGACCCGCAGTAG
CGGCAGCAGCGGCGCCGCCTCCCAGAGTTCAGACCCAGGAAGCGGCCGGGAGGGCAGGAGCGAATCGGGCCGCCGCCGCCATGGAGCTGA
GAGTCGGGAACAGGTACCGGCTGGGCCGGAAGATCGGCAGCGGCTCCTTCGGAGACATCTATCTCGGTACGGACATTGCTGCAGGAGAAG
AGGTTGCCATCAAGCTTGAATGTGTCAAAACCAAACACCCTCAGCTCCACATTGAGAGCAAAATCTACAAGATGATGCAGGGAGGAGTGG
GCATCCCCACCATCAGATGGTGCGGGGCAGAGGGGGACTACAACGTCATGGTGATGGAGCTGCTGGGGCCAAGCCTGGAGGACCTCTTCA
ACTTCTGCTCCAGGAAATTCAGCCTCAAAACCGTCCTGCTGCTTGCTGACCAAATGATCAGTCGCATCGAATACATTCATTCAAAGAACT
TCATCCACCGGGATGTGAAGCCAGACAACTTCCTCATGGGCCTGGGGAAGAAGGGCAACCTGGTGTACATCATCGACTTCGGGCTGGCCA
AGAAGTACCGGGATGCACGCACCCACCAGCACATCCCCTATCGTGAGAACAAGAACCTCACGGGGACGGCGCGGTACGCCTCCATCAACA
CGCACCTTGGAATTGAACAATCCCGAAGAGATGACTTGGAGTCTCTGGGCTACGTGCTAATGTACTTCAACCTGGGCTCTCTCCCCTGGC
AGGGGCTGAAGGCTGCCACCAAGAGACAGAAATACGAAAGGATTAGCGAGAAGAAAATGTCCACCCCCATCGAAGTGTTGTGTAAAGGCT
ACCCTTCCGAATTTGCCACATACCTGAATTTCTGCCGTTCCTTGCGTTTTGACGACAAGCCTGACTACTCGTACCTGCGGCAGCTTTTCC
GGAATCTGTTCCATCGCCAGGGCTTCTCCTATGACTACGTGTTCGACTGGAACATGCTCAAATTTAGCTCCCAGCTCCTCCAGCAGCCGA
CAGGAGGCCCGTCAAGATGCAGGCAGGCATTGCCACCCCAGGGATGAAGACAGCAGCCCAGGCAAAGGCCAAGACCACAGGAGCCTCCCG
GTCTCATCCTGCAAAAGCTAAAGGCTGCCAGAGGCCCCCCAAGATCCGTAACTACAACATTATGGACTGACTTCCTCCCCCCACCCCGCC
CCACTAAGGGGTGCTCGGGGCCTCCGCATGGTGCCTGTGCTTTCACCTACGTGTTGTGGGGGGGTGTGGGCACAGCGTGCAGGGTGGAGG
CAGGGAGCTGCAGGGCAGGCTCCCAAATGCTGCTGAGGCGACCCTGCTGACTGAAGGCCTCCCTGAGCACAGGGCCCATTAAAACCAGGT

>19815_19815_5_CSNK1D-CCDC57_CSNK1D_chr17_80209255_ENST00000314028_CCDC57_chr17_80059742_ENST00000389641_length(amino acids)=431AA_BP=28
MLGEVTSQRDGGGSFRQLKGDLGPEDPSPSAAGRGQAGPVGAGAAAAALGLSHPPRIEALGAAGRQESDGESGAVRGAEPGAGPAVAAAA
APPPRVQTQEAAGRAGANRAAAAMELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPT
IRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYR
DARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSE

--------------------------------------------------------------
>19815_19815_6_CSNK1D-CCDC57_CSNK1D_chr17_80209255_ENST00000314028_CCDC57_chr17_80059742_ENST00000392347_length(transcript)=1632nt_BP=1235nt
GCCCCGCCGGGTTGCTAGGGGAAGTGACGTCACAGCGCGATGGCGGCGGCTCCTTTAGGCAGCTGAAAGGGGATTTAGGCCCGGAAGATC
CGAGTCCATCCGCGGCGGGGAGAGGGCAAGCGGGACCGGTAGGGGCCGGAGCAGCGGCGGCGGCGCTCGGACTGTCCCATCCGCCCCGTA
TTGAGGCGCTGGGAGCGGCGGGGCGACAGGAAAGCGATGGTGAAAGCGGGGCCGTGAGGGGGGCGGAGCCGGGAGCCGGACCCGCAGTAG
CGGCAGCAGCGGCGCCGCCTCCCAGAGTTCAGACCCAGGAAGCGGCCGGGAGGGCAGGAGCGAATCGGGCCGCCGCCGCCATGGAGCTGA
GAGTCGGGAACAGGTACCGGCTGGGCCGGAAGATCGGCAGCGGCTCCTTCGGAGACATCTATCTCGGTACGGACATTGCTGCAGGAGAAG
AGGTTGCCATCAAGCTTGAATGTGTCAAAACCAAACACCCTCAGCTCCACATTGAGAGCAAAATCTACAAGATGATGCAGGGAGGAGTGG
GCATCCCCACCATCAGATGGTGCGGGGCAGAGGGGGACTACAACGTCATGGTGATGGAGCTGCTGGGGCCAAGCCTGGAGGACCTCTTCA
ACTTCTGCTCCAGGAAATTCAGCCTCAAAACCGTCCTGCTGCTTGCTGACCAAATGATCAGTCGCATCGAATACATTCATTCAAAGAACT
TCATCCACCGGGATGTGAAGCCAGACAACTTCCTCATGGGCCTGGGGAAGAAGGGCAACCTGGTGTACATCATCGACTTCGGGCTGGCCA
AGAAGTACCGGGATGCACGCACCCACCAGCACATCCCCTATCGTGAGAACAAGAACCTCACGGGGACGGCGCGGTACGCCTCCATCAACA
CGCACCTTGGAATTGAACAATCCCGAAGAGATGACTTGGAGTCTCTGGGCTACGTGCTAATGTACTTCAACCTGGGCTCTCTCCCCTGGC
AGGGGCTGAAGGCTGCCACCAAGAGACAGAAATACGAAAGGATTAGCGAGAAGAAAATGTCCACCCCCATCGAAGTGTTGTGTAAAGGCT
ACCCTTCCGAATTTGCCACATACCTGAATTTCTGCCGTTCCTTGCGTTTTGACGACAAGCCTGACTACTCGTACCTGCGGCAGCTTTTCC
GGAATCTGTTCCATCGCCAGGGCTTCTCCTATGACTACGTGTTCGACTGGAACATGCTCAAATTTAGCTCCCAGCTCCTCCAGCAGCCGA
CAGGAGGCCCGTCAAGATGCAGGCAGGCATTGCCACCCCAGGGATGAAGACAGCAGCCCAGGCAAAGGCCAAGACCACAGGAGCCTCCCG
GTCTCATCCTGCAAAAGCTAAAGGCTGCCAGAGGCCCCCCAAGATCCGTAACTACAACATTATGGACTGACTTCCTCCCCCCACCCCGCC
CCACTAAGGGGTGCTCGGGGCCTCCGCATGGTGCCTGTGCTTTCACCTACGTGTTGTGGGGGGGTGTGGGCACAGCGTGCAGGGTGGAGG
CAGGGAGCTGCAGGGCAGGCTCCCAAATGCTGCTGAGGCGACCCTGCTGACTGAAGGCCTCCCTGAGCACAGGGCCCATTAAAACCAGGT

>19815_19815_6_CSNK1D-CCDC57_CSNK1D_chr17_80209255_ENST00000314028_CCDC57_chr17_80059742_ENST00000392347_length(amino acids)=431AA_BP=28
MLGEVTSQRDGGGSFRQLKGDLGPEDPSPSAAGRGQAGPVGAGAAAAALGLSHPPRIEALGAAGRQESDGESGAVRGAEPGAGPAVAAAA
APPPRVQTQEAAGRAGANRAAAAMELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPT
IRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYR
DARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSE

--------------------------------------------------------------
>19815_19815_7_CSNK1D-CCDC57_CSNK1D_chr17_80209255_ENST00000398519_CCDC57_chr17_80059742_ENST00000389641_length(transcript)=1329nt_BP=932nt
CCCAGGAAGCGGCCGGGAGGGCAGGAGCGAATCGGGCCGCCGCCGCCATGGAGCTGAGAGTCGGGAACAGGTACCGGCTGGGCCGGAAGA
TCGGCAGCGGCTCCTTCGGAGACATCTATCTCGGTACGGACATTGCTGCAGGAGAAGAGGTTGCCATCAAGCTTGAATGTGTCAAAACCA
AACACCCTCAGCTCCACATTGAGAGCAAAATCTACAAGATGATGCAGGGAGGAGTGGGCATCCCCACCATCAGATGGTGCGGGGCAGAGG
GGGACTACAACGTCATGGTGATGGAGCTGCTGGGGCCAAGCCTGGAGGACCTCTTCAACTTCTGCTCCAGGAAATTCAGCCTCAAAACCG
TCCTGCTGCTTGCTGACCAAATGATCAGTCGCATCGAATACATTCATTCAAAGAACTTCATCCACCGGGATGTGAAGCCAGACAACTTCC
TCATGGGCCTGGGGAAGAAGGGCAACCTGGTGTACATCATCGACTTCGGGCTGGCCAAGAAGTACCGGGATGCACGCACCCACCAGCACA
TCCCCTATCGTGAGAACAAGAACCTCACGGGGACGGCGCGGTACGCCTCCATCAACACGCACCTTGGAATTGAACAATCCCGAAGAGATG
ACTTGGAGTCTCTGGGCTACGTGCTAATGTACTTCAACCTGGGCTCTCTCCCCTGGCAGGGGCTGAAGGCTGCCACCAAGAGACAGAAAT
ACGAAAGGATTAGCGAGAAGAAAATGTCCACCCCCATCGAAGTGTTGTGTAAAGGCTACCCTTCCGAATTTGCCACATACCTGAATTTCT
GCCGTTCCTTGCGTTTTGACGACAAGCCTGACTACTCGTACCTGCGGCAGCTTTTCCGGAATCTGTTCCATCGCCAGGGCTTCTCCTATG
ACTACGTGTTCGACTGGAACATGCTCAAATTTAGCTCCCAGCTCCTCCAGCAGCCGACAGGAGGCCCGTCAAGATGCAGGCAGGCATTGC
CACCCCAGGGATGAAGACAGCAGCCCAGGCAAAGGCCAAGACCACAGGAGCCTCCCGGTCTCATCCTGCAAAAGCTAAAGGCTGCCAGAG
GCCCCCCAAGATCCGTAACTACAACATTATGGACTGACTTCCTCCCCCCACCCCGCCCCACTAAGGGGTGCTCGGGGCCTCCGCATGGTG
CCTGTGCTTTCACCTACGTGTTGTGGGGGGGTGTGGGCACAGCGTGCAGGGTGGAGGCAGGGAGCTGCAGGGCAGGCTCCCAAATGCTGC

>19815_19815_7_CSNK1D-CCDC57_CSNK1D_chr17_80209255_ENST00000398519_CCDC57_chr17_80059742_ENST00000389641_length(amino acids)=318AA_BP=0
MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLE
DLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLR

--------------------------------------------------------------
>19815_19815_8_CSNK1D-CCDC57_CSNK1D_chr17_80209255_ENST00000398519_CCDC57_chr17_80059742_ENST00000392347_length(transcript)=1329nt_BP=932nt
CCCAGGAAGCGGCCGGGAGGGCAGGAGCGAATCGGGCCGCCGCCGCCATGGAGCTGAGAGTCGGGAACAGGTACCGGCTGGGCCGGAAGA
TCGGCAGCGGCTCCTTCGGAGACATCTATCTCGGTACGGACATTGCTGCAGGAGAAGAGGTTGCCATCAAGCTTGAATGTGTCAAAACCA
AACACCCTCAGCTCCACATTGAGAGCAAAATCTACAAGATGATGCAGGGAGGAGTGGGCATCCCCACCATCAGATGGTGCGGGGCAGAGG
GGGACTACAACGTCATGGTGATGGAGCTGCTGGGGCCAAGCCTGGAGGACCTCTTCAACTTCTGCTCCAGGAAATTCAGCCTCAAAACCG
TCCTGCTGCTTGCTGACCAAATGATCAGTCGCATCGAATACATTCATTCAAAGAACTTCATCCACCGGGATGTGAAGCCAGACAACTTCC
TCATGGGCCTGGGGAAGAAGGGCAACCTGGTGTACATCATCGACTTCGGGCTGGCCAAGAAGTACCGGGATGCACGCACCCACCAGCACA
TCCCCTATCGTGAGAACAAGAACCTCACGGGGACGGCGCGGTACGCCTCCATCAACACGCACCTTGGAATTGAACAATCCCGAAGAGATG
ACTTGGAGTCTCTGGGCTACGTGCTAATGTACTTCAACCTGGGCTCTCTCCCCTGGCAGGGGCTGAAGGCTGCCACCAAGAGACAGAAAT
ACGAAAGGATTAGCGAGAAGAAAATGTCCACCCCCATCGAAGTGTTGTGTAAAGGCTACCCTTCCGAATTTGCCACATACCTGAATTTCT
GCCGTTCCTTGCGTTTTGACGACAAGCCTGACTACTCGTACCTGCGGCAGCTTTTCCGGAATCTGTTCCATCGCCAGGGCTTCTCCTATG
ACTACGTGTTCGACTGGAACATGCTCAAATTTAGCTCCCAGCTCCTCCAGCAGCCGACAGGAGGCCCGTCAAGATGCAGGCAGGCATTGC
CACCCCAGGGATGAAGACAGCAGCCCAGGCAAAGGCCAAGACCACAGGAGCCTCCCGGTCTCATCCTGCAAAAGCTAAAGGCTGCCAGAG
GCCCCCCAAGATCCGTAACTACAACATTATGGACTGACTTCCTCCCCCCACCCCGCCCCACTAAGGGGTGCTCGGGGCCTCCGCATGGTG
CCTGTGCTTTCACCTACGTGTTGTGGGGGGGTGTGGGCACAGCGTGCAGGGTGGAGGCAGGGAGCTGCAGGGCAGGCTCCCAAATGCTGC

>19815_19815_8_CSNK1D-CCDC57_CSNK1D_chr17_80209255_ENST00000398519_CCDC57_chr17_80059742_ENST00000392347_length(amino acids)=318AA_BP=0
MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLE
DLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CSNK1D-CCDC57


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CSNK1D-CCDC57


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CSNK1D-CCDC57


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCSNK1DC3808874ADVANCED SLEEP PHASE SYNDROME, FAMILIAL, 23GENOMICS_ENGLAND;UNIPROT
HgeneCSNK1DC1858496Advanced Sleep-Phase Syndrome, Familial1CTD_human;ORPHANET