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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CSNK1E-PLA2G6 (FusionGDB2 ID:HG1454TG8398)

Fusion Gene Summary for CSNK1E-PLA2G6

check button Fusion gene summary
Fusion gene informationFusion gene name: CSNK1E-PLA2G6
Fusion gene ID: hg1454tg8398
HgeneTgene
Gene symbol

CSNK1E

PLA2G6

Gene ID

1454

8398

Gene namecasein kinase 1 epsilonphospholipase A2 group VI
SynonymsCKIe|CKIepsilon|HCKIECaI-PLA2|GVI|INAD1|IPLA2-VIA|NBIA2|NBIA2A|NBIA2B|PARK14|PLA2|PNPLA9|iPLA2|iPLA2beta
Cytomap('CSNK1E')('PLA2G6')

22q13.1

22q13.1

Type of geneprotein-codingprotein-coding
Descriptioncasein kinase I isoform epsilon85/88 kDa calcium-independent phospholipase A285 kDa calcium-independent phospholipase A2GVI PLA2iPLA2-betaintracellular membrane-associated calcium-independent phospholipase A2 betaneurodegeneration with brain iron accumulation 2patatin-like phosph
Modification date2020032920200313
UniProtAcc

P49674

.
Ensembl transtripts involved in fusion geneENST00000359867, ENST00000396832, 
ENST00000400206, ENST00000403904, 
ENST00000405675, ENST00000413574, 
ENST00000498529, 
Fusion gene scores* DoF score13 X 9 X 10=117010 X 9 X 8=720
# samples 1712
** MAII scorelog2(17/1170*10)=-2.78290187833307
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(12/720*10)=-2.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CSNK1E [Title/Abstract] AND PLA2G6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCSNK1E(38689261)-PLA2G6(38512218), # samples:2
Anticipated loss of major functional domain due to fusion event.CSNK1E-PLA2G6 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CSNK1E-PLA2G6 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CSNK1E-PLA2G6 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CSNK1E-PLA2G6 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCSNK1E

GO:0006468

protein phosphorylation

15917222|17244647

HgeneCSNK1E

GO:0018105

peptidyl-serine phosphorylation

25500533

HgeneCSNK1E

GO:0032091

negative regulation of protein binding

23109420

HgeneCSNK1E

GO:0060070

canonical Wnt signaling pathway

14722104

HgeneCSNK1E

GO:1903827

regulation of cellular protein localization

17244647

TgenePLA2G6

GO:0019731

antibacterial humoral response

18714013


check buttonFusion gene breakpoints across CSNK1E (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across PLA2G6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4CESCTCGA-VS-A8EC-01ACSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
ChimerDB4CESCTCGA-VS-A8ECCSNK1Echr22

38689260

-PLA2G6chr22

38512218

-


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Fusion Gene ORF analysis for CSNK1E-PLA2G6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000359867ENST00000332509CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-3CDSENST00000359867ENST00000332509CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-3CDSENST00000359867ENST00000335539CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-3CDSENST00000359867ENST00000335539CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-3CDSENST00000359867ENST00000402064CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-3CDSENST00000359867ENST00000402064CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-3CDSENST00000396832ENST00000332509CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-3CDSENST00000396832ENST00000332509CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-3CDSENST00000396832ENST00000335539CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-3CDSENST00000396832ENST00000335539CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-3CDSENST00000396832ENST00000402064CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-3CDSENST00000396832ENST00000402064CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-3CDSENST00000400206ENST00000332509CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-3CDSENST00000400206ENST00000332509CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-3CDSENST00000400206ENST00000335539CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-3CDSENST00000400206ENST00000335539CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-3CDSENST00000400206ENST00000402064CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-3CDSENST00000400206ENST00000402064CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-intronENST00000359867ENST00000417303CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-intronENST00000359867ENST00000417303CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-intronENST00000359867ENST00000435484CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-intronENST00000359867ENST00000435484CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-intronENST00000359867ENST00000436218CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-intronENST00000359867ENST00000436218CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-intronENST00000359867ENST00000447598CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-intronENST00000359867ENST00000447598CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-intronENST00000359867ENST00000490473CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-intronENST00000359867ENST00000490473CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-intronENST00000396832ENST00000417303CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-intronENST00000396832ENST00000417303CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-intronENST00000396832ENST00000435484CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-intronENST00000396832ENST00000435484CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-intronENST00000396832ENST00000436218CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-intronENST00000396832ENST00000436218CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-intronENST00000396832ENST00000447598CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-intronENST00000396832ENST00000447598CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-intronENST00000396832ENST00000490473CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-intronENST00000396832ENST00000490473CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-intronENST00000400206ENST00000417303CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-intronENST00000400206ENST00000417303CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-intronENST00000400206ENST00000435484CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-intronENST00000400206ENST00000435484CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-intronENST00000400206ENST00000436218CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-intronENST00000400206ENST00000436218CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-intronENST00000400206ENST00000447598CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-intronENST00000400206ENST00000447598CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
3UTR-intronENST00000400206ENST00000490473CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
3UTR-intronENST00000400206ENST00000490473CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
5CDS-intronENST00000403904ENST00000417303CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
5CDS-intronENST00000403904ENST00000417303CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
5CDS-intronENST00000403904ENST00000435484CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
5CDS-intronENST00000403904ENST00000435484CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
5CDS-intronENST00000403904ENST00000436218CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
5CDS-intronENST00000403904ENST00000436218CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
5CDS-intronENST00000403904ENST00000447598CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
5CDS-intronENST00000403904ENST00000447598CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
5CDS-intronENST00000403904ENST00000490473CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
5CDS-intronENST00000403904ENST00000490473CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
In-frameENST00000403904ENST00000332509CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
In-frameENST00000403904ENST00000332509CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
In-frameENST00000403904ENST00000335539CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
In-frameENST00000403904ENST00000335539CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
In-frameENST00000403904ENST00000402064CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
In-frameENST00000403904ENST00000402064CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-3CDSENST00000405675ENST00000332509CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-3CDSENST00000405675ENST00000332509CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-3CDSENST00000405675ENST00000335539CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-3CDSENST00000405675ENST00000335539CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-3CDSENST00000405675ENST00000402064CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-3CDSENST00000405675ENST00000402064CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-3CDSENST00000413574ENST00000332509CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-3CDSENST00000413574ENST00000332509CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-3CDSENST00000413574ENST00000335539CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-3CDSENST00000413574ENST00000335539CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-3CDSENST00000413574ENST00000402064CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-3CDSENST00000413574ENST00000402064CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-3CDSENST00000498529ENST00000332509CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-3CDSENST00000498529ENST00000332509CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-3CDSENST00000498529ENST00000335539CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-3CDSENST00000498529ENST00000335539CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-3CDSENST00000498529ENST00000402064CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-3CDSENST00000498529ENST00000402064CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-intronENST00000405675ENST00000417303CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-intronENST00000405675ENST00000417303CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-intronENST00000405675ENST00000435484CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-intronENST00000405675ENST00000435484CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-intronENST00000405675ENST00000436218CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-intronENST00000405675ENST00000436218CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-intronENST00000405675ENST00000447598CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-intronENST00000405675ENST00000447598CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-intronENST00000405675ENST00000490473CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-intronENST00000405675ENST00000490473CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-intronENST00000413574ENST00000417303CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-intronENST00000413574ENST00000417303CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-intronENST00000413574ENST00000435484CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-intronENST00000413574ENST00000435484CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-intronENST00000413574ENST00000436218CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-intronENST00000413574ENST00000436218CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-intronENST00000413574ENST00000447598CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-intronENST00000413574ENST00000447598CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-intronENST00000413574ENST00000490473CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-intronENST00000413574ENST00000490473CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-intronENST00000498529ENST00000417303CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-intronENST00000498529ENST00000417303CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-intronENST00000498529ENST00000435484CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-intronENST00000498529ENST00000435484CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-intronENST00000498529ENST00000436218CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-intronENST00000498529ENST00000436218CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-intronENST00000498529ENST00000447598CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-intronENST00000498529ENST00000447598CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-
intron-intronENST00000498529ENST00000490473CSNK1Echr22

38689261

-PLA2G6chr22

38512218

-
intron-intronENST00000498529ENST00000490473CSNK1Echr22

38689260

-PLA2G6chr22

38512218

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000403904CSNK1Echr2238689261-ENST00000332509PLA2G6chr2238512218-292515802921542416
ENST00000403904CSNK1Echr2238689261-ENST00000335539PLA2G6chr2238512218-292415802921542416
ENST00000403904CSNK1Echr2238689261-ENST00000402064PLA2G6chr2238512218-292015802921542416
ENST00000403904CSNK1Echr2238689260-ENST00000332509PLA2G6chr2238512218-292515802921542416
ENST00000403904CSNK1Echr2238689260-ENST00000335539PLA2G6chr2238512218-292415802921542416
ENST00000403904CSNK1Echr2238689260-ENST00000402064PLA2G6chr2238512218-292015802921542416

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000403904ENST00000332509CSNK1Echr2238689261-PLA2G6chr2238512218-0.0166378840.98336214
ENST00000403904ENST00000335539CSNK1Echr2238689261-PLA2G6chr2238512218-0.0165884010.9834116
ENST00000403904ENST00000402064CSNK1Echr2238689261-PLA2G6chr2238512218-0.0165531860.98344684
ENST00000403904ENST00000332509CSNK1Echr2238689260-PLA2G6chr2238512218-0.0166378840.98336214
ENST00000403904ENST00000335539CSNK1Echr2238689260-PLA2G6chr2238512218-0.0165884010.9834116
ENST00000403904ENST00000402064CSNK1Echr2238689260-PLA2G6chr2238512218-0.0165531860.98344684

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Fusion Genomic Features for CSNK1E-PLA2G6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for CSNK1E-PLA2G6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:38689261/chr22:38512218)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CSNK1E

P49674

.
FUNCTION: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1 and DVL2. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation. {ECO:0000269|PubMed:12556519, ECO:0000269|PubMed:15070676, ECO:0000269|PubMed:15917222, ECO:0000269|PubMed:16790549, ECO:0000269|PubMed:23413191}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

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* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCSNK1Echr22:38689260chr22:38512218ENST00000359867-10119_277427792.3333333333334DomainProtein kinase
HgeneCSNK1Echr22:38689260chr22:38512218ENST00000396832-10119_277427742.0DomainProtein kinase
HgeneCSNK1Echr22:38689260chr22:38512218ENST00000400206-14159_277427583.0DomainProtein kinase
HgeneCSNK1Echr22:38689260chr22:38512218ENST00000403904-10109_277429417.0DomainProtein kinase
HgeneCSNK1Echr22:38689261chr22:38512218ENST00000359867-10119_277427792.3333333333334DomainProtein kinase
HgeneCSNK1Echr22:38689261chr22:38512218ENST00000396832-10119_277427742.0DomainProtein kinase
HgeneCSNK1Echr22:38689261chr22:38512218ENST00000400206-14159_277427583.0DomainProtein kinase
HgeneCSNK1Echr22:38689261chr22:38512218ENST00000403904-10109_277429417.0DomainProtein kinase
HgeneCSNK1Echr22:38689260chr22:38512218ENST00000359867-101115_23427792.3333333333334Nucleotide bindingATP
HgeneCSNK1Echr22:38689260chr22:38512218ENST00000396832-101115_23427742.0Nucleotide bindingATP
HgeneCSNK1Echr22:38689260chr22:38512218ENST00000400206-141515_23427583.0Nucleotide bindingATP
HgeneCSNK1Echr22:38689260chr22:38512218ENST00000403904-101015_23429417.0Nucleotide bindingATP
HgeneCSNK1Echr22:38689261chr22:38512218ENST00000359867-101115_23427792.3333333333334Nucleotide bindingATP
HgeneCSNK1Echr22:38689261chr22:38512218ENST00000396832-101115_23427742.0Nucleotide bindingATP
HgeneCSNK1Echr22:38689261chr22:38512218ENST00000400206-141515_23427583.0Nucleotide bindingATP
HgeneCSNK1Echr22:38689261chr22:38512218ENST00000403904-101015_23429417.0Nucleotide bindingATP
TgenePLA2G6chr22:38689260chr22:38512218ENST000003325091117652_654580807.0MotifDGA/G
TgenePLA2G6chr22:38689260chr22:38512218ENST000003355391016652_654526753.0MotifDGA/G
TgenePLA2G6chr22:38689260chr22:38512218ENST000004020641016652_654526753.0MotifDGA/G
TgenePLA2G6chr22:38689261chr22:38512218ENST000003325091117652_654580807.0MotifDGA/G
TgenePLA2G6chr22:38689261chr22:38512218ENST000003355391016652_654526753.0MotifDGA/G
TgenePLA2G6chr22:38689261chr22:38512218ENST000004020641016652_654526753.0MotifDGA/G
TgenePLA2G6chr22:38689260chr22:38512218ENST000003325091117677_686580807.0RegionCalmodulin-binding (1-9-14 motif)
TgenePLA2G6chr22:38689260chr22:38512218ENST000003325091117748_759580807.0RegionCalmodulin-binding (IQ motif)
TgenePLA2G6chr22:38689260chr22:38512218ENST000003355391016677_686526753.0RegionCalmodulin-binding (1-9-14 motif)
TgenePLA2G6chr22:38689260chr22:38512218ENST000003355391016748_759526753.0RegionCalmodulin-binding (IQ motif)
TgenePLA2G6chr22:38689260chr22:38512218ENST000004020641016677_686526753.0RegionCalmodulin-binding (1-9-14 motif)
TgenePLA2G6chr22:38689260chr22:38512218ENST000004020641016748_759526753.0RegionCalmodulin-binding (IQ motif)
TgenePLA2G6chr22:38689261chr22:38512218ENST000003325091117677_686580807.0RegionCalmodulin-binding (1-9-14 motif)
TgenePLA2G6chr22:38689261chr22:38512218ENST000003325091117748_759580807.0RegionCalmodulin-binding (IQ motif)
TgenePLA2G6chr22:38689261chr22:38512218ENST000003355391016677_686526753.0RegionCalmodulin-binding (1-9-14 motif)
TgenePLA2G6chr22:38689261chr22:38512218ENST000003355391016748_759526753.0RegionCalmodulin-binding (IQ motif)
TgenePLA2G6chr22:38689261chr22:38512218ENST000004020641016677_686526753.0RegionCalmodulin-binding (1-9-14 motif)
TgenePLA2G6chr22:38689261chr22:38512218ENST000004020641016748_759526753.0RegionCalmodulin-binding (IQ motif)

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePLA2G6chr22:38689260chr22:38512218ENST000003325091117481_665580807.0DomainPNPLA
TgenePLA2G6chr22:38689260chr22:38512218ENST000003355391016481_665526753.0DomainPNPLA
TgenePLA2G6chr22:38689260chr22:38512218ENST000004020641016481_665526753.0DomainPNPLA
TgenePLA2G6chr22:38689261chr22:38512218ENST000003325091117481_665580807.0DomainPNPLA
TgenePLA2G6chr22:38689261chr22:38512218ENST000003355391016481_665526753.0DomainPNPLA
TgenePLA2G6chr22:38689261chr22:38512218ENST000004020641016481_665526753.0DomainPNPLA
TgenePLA2G6chr22:38689260chr22:38512218ENST000003325091117485_490580807.0MotifGXGXXG
TgenePLA2G6chr22:38689260chr22:38512218ENST000003325091117517_521580807.0MotifGXSXG
TgenePLA2G6chr22:38689260chr22:38512218ENST000003355391016485_490526753.0MotifGXGXXG
TgenePLA2G6chr22:38689260chr22:38512218ENST000003355391016517_521526753.0MotifGXSXG
TgenePLA2G6chr22:38689260chr22:38512218ENST000004020641016485_490526753.0MotifGXGXXG
TgenePLA2G6chr22:38689260chr22:38512218ENST000004020641016517_521526753.0MotifGXSXG
TgenePLA2G6chr22:38689261chr22:38512218ENST000003325091117485_490580807.0MotifGXGXXG
TgenePLA2G6chr22:38689261chr22:38512218ENST000003325091117517_521580807.0MotifGXSXG
TgenePLA2G6chr22:38689261chr22:38512218ENST000003355391016485_490526753.0MotifGXGXXG
TgenePLA2G6chr22:38689261chr22:38512218ENST000003355391016517_521526753.0MotifGXSXG
TgenePLA2G6chr22:38689261chr22:38512218ENST000004020641016485_490526753.0MotifGXGXXG
TgenePLA2G6chr22:38689261chr22:38512218ENST000004020641016517_521526753.0MotifGXSXG
TgenePLA2G6chr22:38689260chr22:38512218ENST000003325091117120_147580807.0RepeatANK 1
TgenePLA2G6chr22:38689260chr22:38512218ENST000003325091117151_181580807.0RepeatANK 1
TgenePLA2G6chr22:38689260chr22:38512218ENST000003325091117185_215580807.0RepeatANK 2
TgenePLA2G6chr22:38689260chr22:38512218ENST000003325091117219_248580807.0RepeatANK 3
TgenePLA2G6chr22:38689260chr22:38512218ENST000003325091117251_281580807.0RepeatANK 4
TgenePLA2G6chr22:38689260chr22:38512218ENST000003325091117286_312580807.0RepeatANK 5
TgenePLA2G6chr22:38689260chr22:38512218ENST000003325091117316_345580807.0RepeatANK 6
TgenePLA2G6chr22:38689260chr22:38512218ENST000003325091117349_378580807.0RepeatANK 7
TgenePLA2G6chr22:38689260chr22:38512218ENST000003325091117382_403580807.0RepeatANK 9
TgenePLA2G6chr22:38689260chr22:38512218ENST000003355391016120_147526753.0RepeatANK 1
TgenePLA2G6chr22:38689260chr22:38512218ENST000003355391016151_181526753.0RepeatANK 1
TgenePLA2G6chr22:38689260chr22:38512218ENST000003355391016185_215526753.0RepeatANK 2
TgenePLA2G6chr22:38689260chr22:38512218ENST000003355391016219_248526753.0RepeatANK 3
TgenePLA2G6chr22:38689260chr22:38512218ENST000003355391016251_281526753.0RepeatANK 4
TgenePLA2G6chr22:38689260chr22:38512218ENST000003355391016286_312526753.0RepeatANK 5
TgenePLA2G6chr22:38689260chr22:38512218ENST000003355391016316_345526753.0RepeatANK 6
TgenePLA2G6chr22:38689260chr22:38512218ENST000003355391016349_378526753.0RepeatANK 7
TgenePLA2G6chr22:38689260chr22:38512218ENST000003355391016382_403526753.0RepeatANK 9
TgenePLA2G6chr22:38689260chr22:38512218ENST000004020641016120_147526753.0RepeatANK 1
TgenePLA2G6chr22:38689260chr22:38512218ENST000004020641016151_181526753.0RepeatANK 1
TgenePLA2G6chr22:38689260chr22:38512218ENST000004020641016185_215526753.0RepeatANK 2
TgenePLA2G6chr22:38689260chr22:38512218ENST000004020641016219_248526753.0RepeatANK 3
TgenePLA2G6chr22:38689260chr22:38512218ENST000004020641016251_281526753.0RepeatANK 4
TgenePLA2G6chr22:38689260chr22:38512218ENST000004020641016286_312526753.0RepeatANK 5
TgenePLA2G6chr22:38689260chr22:38512218ENST000004020641016316_345526753.0RepeatANK 6
TgenePLA2G6chr22:38689260chr22:38512218ENST000004020641016349_378526753.0RepeatANK 7
TgenePLA2G6chr22:38689260chr22:38512218ENST000004020641016382_403526753.0RepeatANK 9
TgenePLA2G6chr22:38689261chr22:38512218ENST000003325091117120_147580807.0RepeatANK 1
TgenePLA2G6chr22:38689261chr22:38512218ENST000003325091117151_181580807.0RepeatANK 1
TgenePLA2G6chr22:38689261chr22:38512218ENST000003325091117185_215580807.0RepeatANK 2
TgenePLA2G6chr22:38689261chr22:38512218ENST000003325091117219_248580807.0RepeatANK 3
TgenePLA2G6chr22:38689261chr22:38512218ENST000003325091117251_281580807.0RepeatANK 4
TgenePLA2G6chr22:38689261chr22:38512218ENST000003325091117286_312580807.0RepeatANK 5
TgenePLA2G6chr22:38689261chr22:38512218ENST000003325091117316_345580807.0RepeatANK 6
TgenePLA2G6chr22:38689261chr22:38512218ENST000003325091117349_378580807.0RepeatANK 7
TgenePLA2G6chr22:38689261chr22:38512218ENST000003325091117382_403580807.0RepeatANK 9
TgenePLA2G6chr22:38689261chr22:38512218ENST000003355391016120_147526753.0RepeatANK 1
TgenePLA2G6chr22:38689261chr22:38512218ENST000003355391016151_181526753.0RepeatANK 1
TgenePLA2G6chr22:38689261chr22:38512218ENST000003355391016185_215526753.0RepeatANK 2
TgenePLA2G6chr22:38689261chr22:38512218ENST000003355391016219_248526753.0RepeatANK 3
TgenePLA2G6chr22:38689261chr22:38512218ENST000003355391016251_281526753.0RepeatANK 4
TgenePLA2G6chr22:38689261chr22:38512218ENST000003355391016286_312526753.0RepeatANK 5
TgenePLA2G6chr22:38689261chr22:38512218ENST000003355391016316_345526753.0RepeatANK 6
TgenePLA2G6chr22:38689261chr22:38512218ENST000003355391016349_378526753.0RepeatANK 7
TgenePLA2G6chr22:38689261chr22:38512218ENST000003355391016382_403526753.0RepeatANK 9
TgenePLA2G6chr22:38689261chr22:38512218ENST000004020641016120_147526753.0RepeatANK 1
TgenePLA2G6chr22:38689261chr22:38512218ENST000004020641016151_181526753.0RepeatANK 1
TgenePLA2G6chr22:38689261chr22:38512218ENST000004020641016185_215526753.0RepeatANK 2
TgenePLA2G6chr22:38689261chr22:38512218ENST000004020641016219_248526753.0RepeatANK 3
TgenePLA2G6chr22:38689261chr22:38512218ENST000004020641016251_281526753.0RepeatANK 4
TgenePLA2G6chr22:38689261chr22:38512218ENST000004020641016286_312526753.0RepeatANK 5
TgenePLA2G6chr22:38689261chr22:38512218ENST000004020641016316_345526753.0RepeatANK 6
TgenePLA2G6chr22:38689261chr22:38512218ENST000004020641016349_378526753.0RepeatANK 7
TgenePLA2G6chr22:38689261chr22:38512218ENST000004020641016382_403526753.0RepeatANK 9
TgenePLA2G6chr22:38689260chr22:38512218ENST000003325091117480_500580807.0TransmembraneHelical
TgenePLA2G6chr22:38689260chr22:38512218ENST000003325091117511_531580807.0TransmembraneHelical
TgenePLA2G6chr22:38689260chr22:38512218ENST000003355391016480_500526753.0TransmembraneHelical
TgenePLA2G6chr22:38689260chr22:38512218ENST000003355391016511_531526753.0TransmembraneHelical
TgenePLA2G6chr22:38689260chr22:38512218ENST000004020641016480_500526753.0TransmembraneHelical
TgenePLA2G6chr22:38689260chr22:38512218ENST000004020641016511_531526753.0TransmembraneHelical
TgenePLA2G6chr22:38689261chr22:38512218ENST000003325091117480_500580807.0TransmembraneHelical
TgenePLA2G6chr22:38689261chr22:38512218ENST000003325091117511_531580807.0TransmembraneHelical
TgenePLA2G6chr22:38689261chr22:38512218ENST000003355391016480_500526753.0TransmembraneHelical
TgenePLA2G6chr22:38689261chr22:38512218ENST000003355391016511_531526753.0TransmembraneHelical
TgenePLA2G6chr22:38689261chr22:38512218ENST000004020641016480_500526753.0TransmembraneHelical
TgenePLA2G6chr22:38689261chr22:38512218ENST000004020641016511_531526753.0TransmembraneHelical


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Fusion Gene Sequence for CSNK1E-PLA2G6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>19840_19840_1_CSNK1E-PLA2G6_CSNK1E_chr22_38689260_ENST00000403904_PLA2G6_chr22_38512218_ENST00000332509_length(transcript)=2925nt_BP=1580nt
CGGTGCGAGAGCGCGCGAGCCGGCGGCGGGGGCGGGCGGGCGGGCAGGAGGCCGGGAGGAGGGAGGCGGCGGCGGCGGCGGCGGCGGCGG
CGAGAGCCCAGAGCCAGAGCCCGGCCGGGGCCGAGCGGAGCGCGGCGGCGGCGGCGGCGGCGGCGGCTGGGCCGGGAGAGGCTGGCGCGC
CGGGCGGCTCCGCGAATCCTCCGGCATCCGCCCCGGCGGGCCGCCCCCGCCCGCGGCAGCCCCCCGAGCAGTGGCCCGGCATCGGCGCCT
TCCCGGCGGGCAAGAGTGAGCCATGGAGCTACGTGTGGGGAACAAGTACCGCCTGGGACGGAAGATCGGGAGCGGGTCCTTCGGAGATAT
CTACCTGGGTGCCAACATCGCCTCTGGTGAGGAAGTCGCCATCAAGCTGGAGTGTGTGAAGACAAAGCACCCCCAGCTGCACATCGAGAG
CAAGTTCTACAAGATGATGCAGGGTGGCGTGGGGATCCCGTCCATCAAGTGGTGCGGAGCTGAGGGCGACTACAACGTGATGGTCATGGA
GCTGCTGGGGCCTAGCCTCGAGGACCTGTTCAACTTCTGTTCCCGCAAATTCAGCCTCAAGACGGTGCTGCTCTTGGCCGACCAGATGAT
CAGCCGCATCGAGTATATCCACTCCAAGAACTTCATCCACCGGGACGTCAAGCCCGACAACTTCCTCATGGGGCTGGGGAAGAAGGGCAA
CCTGGTCTACATCATCGACTTCGGCCTGGCCAAGAAGTACCGGGACGCCCGCACCCACCAGCACATTCCCTACCGGGAAAACAAGAACCT
GACCGGCACGGCCCGCTACGCTTCCATCAACACGCACCTGGGCATTGAGCAAAGCCGTCGAGATGACCTGGAGAGCCTGGGCTACGTGCT
CATGTACTTCAACCTGGGCTCCCTGCCCTGGCAGGGGCTCAAAGCAGCCACCAAGCGCCAGAAGTATGAACGGATCAGCGAGAAGAAGAT
GTCAACGCCCATCGAGGTCCTCTGCAAAGGCTATCCCTCCGAATTCTCAACATACCTCAACTTCTGCCGCTCCCTGCGGTTTGACGACAA
GCCCGACTACTCTTACCTACGTCAGCTCTTCCGCAACCTCTTCCACCGGCAGGGCTTCTCCTATGACTACGTCTTTGACTGGAACATGCT
GAAATTCGGTGCAGCCCGGAATCCCGAGGATGTGGACCGGGAGCGGCGAGAACACGAACGCGAGGAGAGGATGGGGCAGCTACGGGGGTC
CGCGACCCGAGCCCTGCCCCCTGGCCCACCCACGGGGGCCACTGCCAACCGGCTCCGCAGTGCCGCCGAGCCCGTGGCTTCCACGCCAGC
CTCCCGCATCCAGCCGGCTGGCAATACTTCTCCCAGAGCGATCTCGCGGGTCGACCGGGAGAGGAAGGTGAGTATGAGGCTGCACAGGGG
TGCGCCCGCCAACGTCTCCTCCTCAGACCTCACTGGGCGGCAAGAGGTCTCCCGGATCCCAGCCTCACAGACAAGTGTGCCATTTGACCA
TCTCGGGAAGTGAGGAGAGCCCCCATTGGACCAGTGTTTGCTTAGGTGAGGGTGATGCTGACAGGGACACTGTCTGACCGGCAGCCGGCT
GAACTCCACCTCTTCCGGAACTACGATGCTCCAGAAACTGTCCGGGAGCCTCGTTTCAACCAGAACGTTAACCTCAGGCCTCCAGCTCAG
CCCTCAGACCAGCTGGTGTGGCGGGCGGCCCGAAGCAGCGGGGCAGCTCCTACTTACTTCCGACCCAATGGGCGCTTCCTGGACGGTGGG
CTGCTGGCCAACAACCCCACGCTGGATGCCATGACCGAGATCCATGAGTACAATCAGGACCTGATCCGCAAGGGTCAGGCCAACAAGGTG
AAGAAACTCTCCATCGTTGTCTCCCTGGGGACAGGGAGGTCCCCACAAGTGCCTGTGACCTGTGTGGATGTCTTCCGTCCCAGCAACCCC
TGGGAGCTGGCCAAGACTGTTTTTGGGGCCAAGGAACTGGGCAAGATGGTGGTGGACTGTTGCACGGATCCAGACGGGCGGGCTGTGGAC
CGGGCACGGGCCTGGTGCGAGATGGTCGGCATCCAGTACTTCAGATTGAACCCCCAGCTGGGGACGGACATCATGCTGGATGAGGTCAGT
GACACAGTGCTGGTCAACGCCCTCTGGGAGACCGAGGTCTACATCTATGAGCACCGCGAGGAGTTCCAGAAGCTCATCCAGCTGCTGCTC
TCACCCTGAGGGTCCCCAGCCTCTCACCGGCCCCAGCTGACCTCGTCCATTCAGCCCCTGCCAGGCCAAGCCCAGCCACTGCCCTCCCGG
GCAGATCTGGGCCCAGGCACCTCTGAGTCCATAGACCAGGCCTGGGAGAATGCCAAGCTGCCTGCCCGAGGCTGGTCCTGAAGGCCTGTC
TCCCACTAACCCCGCCTTCCAGCACTTTCTGTCATTCCAGGCTGGGAAAGTCTAGAGCCCCCTTTGGCCCCTTTCCCTGACTGTCAAGGA
CAACTGACTCCCCCATCAGCTCAAACATTAAGGGTACCCGGGCACAACCGTACCCCTGCCCCCAGCCCCAGCCTCCCTGAGGGCCTGCCG
GGCTGCCTCTGCCCCAGCCCCCAGCAAGGGCACTCCCAGGCTTCCTGGTGGGTGCAGCCCACTCCCTCTGCCCTCTGCTCCGTTCCCTGG
GGGCTGGGACTAAAGAAATGGGTGTCCCCCACCCCATCAGCTGGGAAAGCCCAGGCCGCAGGAGTGGGATGCCCGTTGGACTTTGCCCCT
CACACTGGCCCAGCCCCTCACACTGCCCCACCCCGAGAACCCTCAGCTCTCAAAGGTCACTCCTGGGAGTTTCTTCTTCCCAATGGAAGT

>19840_19840_1_CSNK1E-PLA2G6_CSNK1E_chr22_38689260_ENST00000403904_PLA2G6_chr22_38512218_ENST00000332509_length(amino acids)=416AA_BP=
MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLE
DLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLR
QLFRNLFHRQGFSYDYVFDWNMLKFGAARNPEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG

--------------------------------------------------------------
>19840_19840_2_CSNK1E-PLA2G6_CSNK1E_chr22_38689260_ENST00000403904_PLA2G6_chr22_38512218_ENST00000335539_length(transcript)=2924nt_BP=1580nt
CGGTGCGAGAGCGCGCGAGCCGGCGGCGGGGGCGGGCGGGCGGGCAGGAGGCCGGGAGGAGGGAGGCGGCGGCGGCGGCGGCGGCGGCGG
CGAGAGCCCAGAGCCAGAGCCCGGCCGGGGCCGAGCGGAGCGCGGCGGCGGCGGCGGCGGCGGCGGCTGGGCCGGGAGAGGCTGGCGCGC
CGGGCGGCTCCGCGAATCCTCCGGCATCCGCCCCGGCGGGCCGCCCCCGCCCGCGGCAGCCCCCCGAGCAGTGGCCCGGCATCGGCGCCT
TCCCGGCGGGCAAGAGTGAGCCATGGAGCTACGTGTGGGGAACAAGTACCGCCTGGGACGGAAGATCGGGAGCGGGTCCTTCGGAGATAT
CTACCTGGGTGCCAACATCGCCTCTGGTGAGGAAGTCGCCATCAAGCTGGAGTGTGTGAAGACAAAGCACCCCCAGCTGCACATCGAGAG
CAAGTTCTACAAGATGATGCAGGGTGGCGTGGGGATCCCGTCCATCAAGTGGTGCGGAGCTGAGGGCGACTACAACGTGATGGTCATGGA
GCTGCTGGGGCCTAGCCTCGAGGACCTGTTCAACTTCTGTTCCCGCAAATTCAGCCTCAAGACGGTGCTGCTCTTGGCCGACCAGATGAT
CAGCCGCATCGAGTATATCCACTCCAAGAACTTCATCCACCGGGACGTCAAGCCCGACAACTTCCTCATGGGGCTGGGGAAGAAGGGCAA
CCTGGTCTACATCATCGACTTCGGCCTGGCCAAGAAGTACCGGGACGCCCGCACCCACCAGCACATTCCCTACCGGGAAAACAAGAACCT
GACCGGCACGGCCCGCTACGCTTCCATCAACACGCACCTGGGCATTGAGCAAAGCCGTCGAGATGACCTGGAGAGCCTGGGCTACGTGCT
CATGTACTTCAACCTGGGCTCCCTGCCCTGGCAGGGGCTCAAAGCAGCCACCAAGCGCCAGAAGTATGAACGGATCAGCGAGAAGAAGAT
GTCAACGCCCATCGAGGTCCTCTGCAAAGGCTATCCCTCCGAATTCTCAACATACCTCAACTTCTGCCGCTCCCTGCGGTTTGACGACAA
GCCCGACTACTCTTACCTACGTCAGCTCTTCCGCAACCTCTTCCACCGGCAGGGCTTCTCCTATGACTACGTCTTTGACTGGAACATGCT
GAAATTCGGTGCAGCCCGGAATCCCGAGGATGTGGACCGGGAGCGGCGAGAACACGAACGCGAGGAGAGGATGGGGCAGCTACGGGGGTC
CGCGACCCGAGCCCTGCCCCCTGGCCCACCCACGGGGGCCACTGCCAACCGGCTCCGCAGTGCCGCCGAGCCCGTGGCTTCCACGCCAGC
CTCCCGCATCCAGCCGGCTGGCAATACTTCTCCCAGAGCGATCTCGCGGGTCGACCGGGAGAGGAAGGTGAGTATGAGGCTGCACAGGGG
TGCGCCCGCCAACGTCTCCTCCTCAGACCTCACTGGGCGGCAAGAGGTCTCCCGGATCCCAGCCTCACAGACAAGTGTGCCATTTGACCA
TCTCGGGAAGTGAGGAGAGCCCCCATTGGACCAGTGTTTGCTTAGGTGAGGGTGATGCTGACAGGGACACTGTCTGACCGGCAGCCGGCT
GAACTCCACCTCTTCCGGAACTACGATGCTCCAGAAACTGTCCGGGAGCCTCGTTTCAACCAGAACGTTAACCTCAGGCCTCCAGCTCAG
CCCTCAGACCAGCTGGTGTGGCGGGCGGCCCGAAGCAGCGGGGCAGCTCCTACTTACTTCCGACCCAATGGGCGCTTCCTGGACGGTGGG
CTGCTGGCCAACAACCCCACGCTGGATGCCATGACCGAGATCCATGAGTACAATCAGGACCTGATCCGCAAGGGTCAGGCCAACAAGGTG
AAGAAACTCTCCATCGTTGTCTCCCTGGGGACAGGGAGGTCCCCACAAGTGCCTGTGACCTGTGTGGATGTCTTCCGTCCCAGCAACCCC
TGGGAGCTGGCCAAGACTGTTTTTGGGGCCAAGGAACTGGGCAAGATGGTGGTGGACTGTTGCACGGATCCAGACGGGCGGGCTGTGGAC
CGGGCACGGGCCTGGTGCGAGATGGTCGGCATCCAGTACTTCAGATTGAACCCCCAGCTGGGGACGGACATCATGCTGGATGAGGTCAGT
GACACAGTGCTGGTCAACGCCCTCTGGGAGACCGAGGTCTACATCTATGAGCACCGCGAGGAGTTCCAGAAGCTCATCCAGCTGCTGCTC
TCACCCTGAGGGTCCCCAGCCTCTCACCGGCCCCAGCTGACCTCGTCCATTCAGCCCCTGCCAGGCCAAGCCCAGCCACTGCCCTCCCGG
GCAGATCTGGGCCCAGGCACCTCTGAGTCCATAGACCAGGCCTGGGAGAATGCCAAGCTGCCTGCCCGAGGCTGGTCCTGAAGGCCTGTC
TCCCACTAACCCCGCCTTCCAGCACTTTCTGTCATTCCAGGCTGGGAAAGTCTAGAGCCCCCTTTGGCCCCTTTCCCTGACTGTCAAGGA
CAACTGACTCCCCCATCAGCTCAAACATTAAGGGTACCCGGGCACAACCGTACCCCTGCCCCCAGCCCCAGCCTCCCTGAGGGCCTGCCG
GGCTGCCTCTGCCCCAGCCCCCAGCAAGGGCACTCCCAGGCTTCCTGGTGGGTGCAGCCCACTCCCTCTGCCCTCTGCTCCGTTCCCTGG
GGGCTGGGACTAAAGAAATGGGTGTCCCCCACCCCATCAGCTGGGAAAGCCCAGGCCGCAGGAGTGGGATGCCCGTTGGACTTTGCCCCT
CACACTGGCCCAGCCCCTCACACTGCCCCACCCCGAGAACCCTCAGCTCTCAAAGGTCACTCCTGGGAGTTTCTTCTTCCCAATGGAAGT

>19840_19840_2_CSNK1E-PLA2G6_CSNK1E_chr22_38689260_ENST00000403904_PLA2G6_chr22_38512218_ENST00000335539_length(amino acids)=416AA_BP=
MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLE
DLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLR
QLFRNLFHRQGFSYDYVFDWNMLKFGAARNPEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG

--------------------------------------------------------------
>19840_19840_3_CSNK1E-PLA2G6_CSNK1E_chr22_38689260_ENST00000403904_PLA2G6_chr22_38512218_ENST00000402064_length(transcript)=2920nt_BP=1580nt
CGGTGCGAGAGCGCGCGAGCCGGCGGCGGGGGCGGGCGGGCGGGCAGGAGGCCGGGAGGAGGGAGGCGGCGGCGGCGGCGGCGGCGGCGG
CGAGAGCCCAGAGCCAGAGCCCGGCCGGGGCCGAGCGGAGCGCGGCGGCGGCGGCGGCGGCGGCGGCTGGGCCGGGAGAGGCTGGCGCGC
CGGGCGGCTCCGCGAATCCTCCGGCATCCGCCCCGGCGGGCCGCCCCCGCCCGCGGCAGCCCCCCGAGCAGTGGCCCGGCATCGGCGCCT
TCCCGGCGGGCAAGAGTGAGCCATGGAGCTACGTGTGGGGAACAAGTACCGCCTGGGACGGAAGATCGGGAGCGGGTCCTTCGGAGATAT
CTACCTGGGTGCCAACATCGCCTCTGGTGAGGAAGTCGCCATCAAGCTGGAGTGTGTGAAGACAAAGCACCCCCAGCTGCACATCGAGAG
CAAGTTCTACAAGATGATGCAGGGTGGCGTGGGGATCCCGTCCATCAAGTGGTGCGGAGCTGAGGGCGACTACAACGTGATGGTCATGGA
GCTGCTGGGGCCTAGCCTCGAGGACCTGTTCAACTTCTGTTCCCGCAAATTCAGCCTCAAGACGGTGCTGCTCTTGGCCGACCAGATGAT
CAGCCGCATCGAGTATATCCACTCCAAGAACTTCATCCACCGGGACGTCAAGCCCGACAACTTCCTCATGGGGCTGGGGAAGAAGGGCAA
CCTGGTCTACATCATCGACTTCGGCCTGGCCAAGAAGTACCGGGACGCCCGCACCCACCAGCACATTCCCTACCGGGAAAACAAGAACCT
GACCGGCACGGCCCGCTACGCTTCCATCAACACGCACCTGGGCATTGAGCAAAGCCGTCGAGATGACCTGGAGAGCCTGGGCTACGTGCT
CATGTACTTCAACCTGGGCTCCCTGCCCTGGCAGGGGCTCAAAGCAGCCACCAAGCGCCAGAAGTATGAACGGATCAGCGAGAAGAAGAT
GTCAACGCCCATCGAGGTCCTCTGCAAAGGCTATCCCTCCGAATTCTCAACATACCTCAACTTCTGCCGCTCCCTGCGGTTTGACGACAA
GCCCGACTACTCTTACCTACGTCAGCTCTTCCGCAACCTCTTCCACCGGCAGGGCTTCTCCTATGACTACGTCTTTGACTGGAACATGCT
GAAATTCGGTGCAGCCCGGAATCCCGAGGATGTGGACCGGGAGCGGCGAGAACACGAACGCGAGGAGAGGATGGGGCAGCTACGGGGGTC
CGCGACCCGAGCCCTGCCCCCTGGCCCACCCACGGGGGCCACTGCCAACCGGCTCCGCAGTGCCGCCGAGCCCGTGGCTTCCACGCCAGC
CTCCCGCATCCAGCCGGCTGGCAATACTTCTCCCAGAGCGATCTCGCGGGTCGACCGGGAGAGGAAGGTGAGTATGAGGCTGCACAGGGG
TGCGCCCGCCAACGTCTCCTCCTCAGACCTCACTGGGCGGCAAGAGGTCTCCCGGATCCCAGCCTCACAGACAAGTGTGCCATTTGACCA
TCTCGGGAAGTGAGGAGAGCCCCCATTGGACCAGTGTTTGCTTAGGTGAGGGTGATGCTGACAGGGACACTGTCTGACCGGCAGCCGGCT
GAACTCCACCTCTTCCGGAACTACGATGCTCCAGAAACTGTCCGGGAGCCTCGTTTCAACCAGAACGTTAACCTCAGGCCTCCAGCTCAG
CCCTCAGACCAGCTGGTGTGGCGGGCGGCCCGAAGCAGCGGGGCAGCTCCTACTTACTTCCGACCCAATGGGCGCTTCCTGGACGGTGGG
CTGCTGGCCAACAACCCCACGCTGGATGCCATGACCGAGATCCATGAGTACAATCAGGACCTGATCCGCAAGGGTCAGGCCAACAAGGTG
AAGAAACTCTCCATCGTTGTCTCCCTGGGGACAGGGAGGTCCCCACAAGTGCCTGTGACCTGTGTGGATGTCTTCCGTCCCAGCAACCCC
TGGGAGCTGGCCAAGACTGTTTTTGGGGCCAAGGAACTGGGCAAGATGGTGGTGGACTGTTGCACGGATCCAGACGGGCGGGCTGTGGAC
CGGGCACGGGCCTGGTGCGAGATGGTCGGCATCCAGTACTTCAGATTGAACCCCCAGCTGGGGACGGACATCATGCTGGATGAGGTCAGT
GACACAGTGCTGGTCAACGCCCTCTGGGAGACCGAGGTCTACATCTATGAGCACCGCGAGGAGTTCCAGAAGCTCATCCAGCTGCTGCTC
TCACCCTGAGGGTCCCCAGCCTCTCACCGGCCCCAGCTGACCTCGTCCATTCAGCCCCTGCCAGGCCAAGCCCAGCCACTGCCCTCCCGG
GCAGATCTGGGCCCAGGCACCTCTGAGTCCATAGACCAGGCCTGGGAGAATGCCAAGCTGCCTGCCCGAGGCTGGTCCTGAAGGCCTGTC
TCCCACTAACCCCGCCTTCCAGCACTTTCTGTCATTCCAGGCTGGGAAAGTCTAGAGCCCCCTTTGGCCCCTTTCCCTGACTGTCAAGGA
CAACTGACTCCCCCATCAGCTCAAACATTAAGGGTACCCGGGCACAACCGTACCCCTGCCCCCAGCCCCAGCCTCCCTGAGGGCCTGCCG
GGCTGCCTCTGCCCCAGCCCCCAGCAAGGGCACTCCCAGGCTTCCTGGTGGGTGCAGCCCACTCCCTCTGCCCTCTGCTCCGTTCCCTGG
GGGCTGGGACTAAAGAAATGGGTGTCCCCCACCCCATCAGCTGGGAAAGCCCAGGCCGCAGGAGTGGGATGCCCGTTGGACTTTGCCCCT
CACACTGGCCCAGCCCCTCACACTGCCCCACCCCGAGAACCCTCAGCTCTCAAAGGTCACTCCTGGGAGTTTCTTCTTCCCAATGGAAGT

>19840_19840_3_CSNK1E-PLA2G6_CSNK1E_chr22_38689260_ENST00000403904_PLA2G6_chr22_38512218_ENST00000402064_length(amino acids)=416AA_BP=
MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLE
DLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLR
QLFRNLFHRQGFSYDYVFDWNMLKFGAARNPEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG

--------------------------------------------------------------
>19840_19840_4_CSNK1E-PLA2G6_CSNK1E_chr22_38689261_ENST00000403904_PLA2G6_chr22_38512218_ENST00000332509_length(transcript)=2925nt_BP=1580nt
CGGTGCGAGAGCGCGCGAGCCGGCGGCGGGGGCGGGCGGGCGGGCAGGAGGCCGGGAGGAGGGAGGCGGCGGCGGCGGCGGCGGCGGCGG
CGAGAGCCCAGAGCCAGAGCCCGGCCGGGGCCGAGCGGAGCGCGGCGGCGGCGGCGGCGGCGGCGGCTGGGCCGGGAGAGGCTGGCGCGC
CGGGCGGCTCCGCGAATCCTCCGGCATCCGCCCCGGCGGGCCGCCCCCGCCCGCGGCAGCCCCCCGAGCAGTGGCCCGGCATCGGCGCCT
TCCCGGCGGGCAAGAGTGAGCCATGGAGCTACGTGTGGGGAACAAGTACCGCCTGGGACGGAAGATCGGGAGCGGGTCCTTCGGAGATAT
CTACCTGGGTGCCAACATCGCCTCTGGTGAGGAAGTCGCCATCAAGCTGGAGTGTGTGAAGACAAAGCACCCCCAGCTGCACATCGAGAG
CAAGTTCTACAAGATGATGCAGGGTGGCGTGGGGATCCCGTCCATCAAGTGGTGCGGAGCTGAGGGCGACTACAACGTGATGGTCATGGA
GCTGCTGGGGCCTAGCCTCGAGGACCTGTTCAACTTCTGTTCCCGCAAATTCAGCCTCAAGACGGTGCTGCTCTTGGCCGACCAGATGAT
CAGCCGCATCGAGTATATCCACTCCAAGAACTTCATCCACCGGGACGTCAAGCCCGACAACTTCCTCATGGGGCTGGGGAAGAAGGGCAA
CCTGGTCTACATCATCGACTTCGGCCTGGCCAAGAAGTACCGGGACGCCCGCACCCACCAGCACATTCCCTACCGGGAAAACAAGAACCT
GACCGGCACGGCCCGCTACGCTTCCATCAACACGCACCTGGGCATTGAGCAAAGCCGTCGAGATGACCTGGAGAGCCTGGGCTACGTGCT
CATGTACTTCAACCTGGGCTCCCTGCCCTGGCAGGGGCTCAAAGCAGCCACCAAGCGCCAGAAGTATGAACGGATCAGCGAGAAGAAGAT
GTCAACGCCCATCGAGGTCCTCTGCAAAGGCTATCCCTCCGAATTCTCAACATACCTCAACTTCTGCCGCTCCCTGCGGTTTGACGACAA
GCCCGACTACTCTTACCTACGTCAGCTCTTCCGCAACCTCTTCCACCGGCAGGGCTTCTCCTATGACTACGTCTTTGACTGGAACATGCT
GAAATTCGGTGCAGCCCGGAATCCCGAGGATGTGGACCGGGAGCGGCGAGAACACGAACGCGAGGAGAGGATGGGGCAGCTACGGGGGTC
CGCGACCCGAGCCCTGCCCCCTGGCCCACCCACGGGGGCCACTGCCAACCGGCTCCGCAGTGCCGCCGAGCCCGTGGCTTCCACGCCAGC
CTCCCGCATCCAGCCGGCTGGCAATACTTCTCCCAGAGCGATCTCGCGGGTCGACCGGGAGAGGAAGGTGAGTATGAGGCTGCACAGGGG
TGCGCCCGCCAACGTCTCCTCCTCAGACCTCACTGGGCGGCAAGAGGTCTCCCGGATCCCAGCCTCACAGACAAGTGTGCCATTTGACCA
TCTCGGGAAGTGAGGAGAGCCCCCATTGGACCAGTGTTTGCTTAGGTGAGGGTGATGCTGACAGGGACACTGTCTGACCGGCAGCCGGCT
GAACTCCACCTCTTCCGGAACTACGATGCTCCAGAAACTGTCCGGGAGCCTCGTTTCAACCAGAACGTTAACCTCAGGCCTCCAGCTCAG
CCCTCAGACCAGCTGGTGTGGCGGGCGGCCCGAAGCAGCGGGGCAGCTCCTACTTACTTCCGACCCAATGGGCGCTTCCTGGACGGTGGG
CTGCTGGCCAACAACCCCACGCTGGATGCCATGACCGAGATCCATGAGTACAATCAGGACCTGATCCGCAAGGGTCAGGCCAACAAGGTG
AAGAAACTCTCCATCGTTGTCTCCCTGGGGACAGGGAGGTCCCCACAAGTGCCTGTGACCTGTGTGGATGTCTTCCGTCCCAGCAACCCC
TGGGAGCTGGCCAAGACTGTTTTTGGGGCCAAGGAACTGGGCAAGATGGTGGTGGACTGTTGCACGGATCCAGACGGGCGGGCTGTGGAC
CGGGCACGGGCCTGGTGCGAGATGGTCGGCATCCAGTACTTCAGATTGAACCCCCAGCTGGGGACGGACATCATGCTGGATGAGGTCAGT
GACACAGTGCTGGTCAACGCCCTCTGGGAGACCGAGGTCTACATCTATGAGCACCGCGAGGAGTTCCAGAAGCTCATCCAGCTGCTGCTC
TCACCCTGAGGGTCCCCAGCCTCTCACCGGCCCCAGCTGACCTCGTCCATTCAGCCCCTGCCAGGCCAAGCCCAGCCACTGCCCTCCCGG
GCAGATCTGGGCCCAGGCACCTCTGAGTCCATAGACCAGGCCTGGGAGAATGCCAAGCTGCCTGCCCGAGGCTGGTCCTGAAGGCCTGTC
TCCCACTAACCCCGCCTTCCAGCACTTTCTGTCATTCCAGGCTGGGAAAGTCTAGAGCCCCCTTTGGCCCCTTTCCCTGACTGTCAAGGA
CAACTGACTCCCCCATCAGCTCAAACATTAAGGGTACCCGGGCACAACCGTACCCCTGCCCCCAGCCCCAGCCTCCCTGAGGGCCTGCCG
GGCTGCCTCTGCCCCAGCCCCCAGCAAGGGCACTCCCAGGCTTCCTGGTGGGTGCAGCCCACTCCCTCTGCCCTCTGCTCCGTTCCCTGG
GGGCTGGGACTAAAGAAATGGGTGTCCCCCACCCCATCAGCTGGGAAAGCCCAGGCCGCAGGAGTGGGATGCCCGTTGGACTTTGCCCCT
CACACTGGCCCAGCCCCTCACACTGCCCCACCCCGAGAACCCTCAGCTCTCAAAGGTCACTCCTGGGAGTTTCTTCTTCCCAATGGAAGT

>19840_19840_4_CSNK1E-PLA2G6_CSNK1E_chr22_38689261_ENST00000403904_PLA2G6_chr22_38512218_ENST00000332509_length(amino acids)=416AA_BP=
MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLE
DLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLR
QLFRNLFHRQGFSYDYVFDWNMLKFGAARNPEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG

--------------------------------------------------------------
>19840_19840_5_CSNK1E-PLA2G6_CSNK1E_chr22_38689261_ENST00000403904_PLA2G6_chr22_38512218_ENST00000335539_length(transcript)=2924nt_BP=1580nt
CGGTGCGAGAGCGCGCGAGCCGGCGGCGGGGGCGGGCGGGCGGGCAGGAGGCCGGGAGGAGGGAGGCGGCGGCGGCGGCGGCGGCGGCGG
CGAGAGCCCAGAGCCAGAGCCCGGCCGGGGCCGAGCGGAGCGCGGCGGCGGCGGCGGCGGCGGCGGCTGGGCCGGGAGAGGCTGGCGCGC
CGGGCGGCTCCGCGAATCCTCCGGCATCCGCCCCGGCGGGCCGCCCCCGCCCGCGGCAGCCCCCCGAGCAGTGGCCCGGCATCGGCGCCT
TCCCGGCGGGCAAGAGTGAGCCATGGAGCTACGTGTGGGGAACAAGTACCGCCTGGGACGGAAGATCGGGAGCGGGTCCTTCGGAGATAT
CTACCTGGGTGCCAACATCGCCTCTGGTGAGGAAGTCGCCATCAAGCTGGAGTGTGTGAAGACAAAGCACCCCCAGCTGCACATCGAGAG
CAAGTTCTACAAGATGATGCAGGGTGGCGTGGGGATCCCGTCCATCAAGTGGTGCGGAGCTGAGGGCGACTACAACGTGATGGTCATGGA
GCTGCTGGGGCCTAGCCTCGAGGACCTGTTCAACTTCTGTTCCCGCAAATTCAGCCTCAAGACGGTGCTGCTCTTGGCCGACCAGATGAT
CAGCCGCATCGAGTATATCCACTCCAAGAACTTCATCCACCGGGACGTCAAGCCCGACAACTTCCTCATGGGGCTGGGGAAGAAGGGCAA
CCTGGTCTACATCATCGACTTCGGCCTGGCCAAGAAGTACCGGGACGCCCGCACCCACCAGCACATTCCCTACCGGGAAAACAAGAACCT
GACCGGCACGGCCCGCTACGCTTCCATCAACACGCACCTGGGCATTGAGCAAAGCCGTCGAGATGACCTGGAGAGCCTGGGCTACGTGCT
CATGTACTTCAACCTGGGCTCCCTGCCCTGGCAGGGGCTCAAAGCAGCCACCAAGCGCCAGAAGTATGAACGGATCAGCGAGAAGAAGAT
GTCAACGCCCATCGAGGTCCTCTGCAAAGGCTATCCCTCCGAATTCTCAACATACCTCAACTTCTGCCGCTCCCTGCGGTTTGACGACAA
GCCCGACTACTCTTACCTACGTCAGCTCTTCCGCAACCTCTTCCACCGGCAGGGCTTCTCCTATGACTACGTCTTTGACTGGAACATGCT
GAAATTCGGTGCAGCCCGGAATCCCGAGGATGTGGACCGGGAGCGGCGAGAACACGAACGCGAGGAGAGGATGGGGCAGCTACGGGGGTC
CGCGACCCGAGCCCTGCCCCCTGGCCCACCCACGGGGGCCACTGCCAACCGGCTCCGCAGTGCCGCCGAGCCCGTGGCTTCCACGCCAGC
CTCCCGCATCCAGCCGGCTGGCAATACTTCTCCCAGAGCGATCTCGCGGGTCGACCGGGAGAGGAAGGTGAGTATGAGGCTGCACAGGGG
TGCGCCCGCCAACGTCTCCTCCTCAGACCTCACTGGGCGGCAAGAGGTCTCCCGGATCCCAGCCTCACAGACAAGTGTGCCATTTGACCA
TCTCGGGAAGTGAGGAGAGCCCCCATTGGACCAGTGTTTGCTTAGGTGAGGGTGATGCTGACAGGGACACTGTCTGACCGGCAGCCGGCT
GAACTCCACCTCTTCCGGAACTACGATGCTCCAGAAACTGTCCGGGAGCCTCGTTTCAACCAGAACGTTAACCTCAGGCCTCCAGCTCAG
CCCTCAGACCAGCTGGTGTGGCGGGCGGCCCGAAGCAGCGGGGCAGCTCCTACTTACTTCCGACCCAATGGGCGCTTCCTGGACGGTGGG
CTGCTGGCCAACAACCCCACGCTGGATGCCATGACCGAGATCCATGAGTACAATCAGGACCTGATCCGCAAGGGTCAGGCCAACAAGGTG
AAGAAACTCTCCATCGTTGTCTCCCTGGGGACAGGGAGGTCCCCACAAGTGCCTGTGACCTGTGTGGATGTCTTCCGTCCCAGCAACCCC
TGGGAGCTGGCCAAGACTGTTTTTGGGGCCAAGGAACTGGGCAAGATGGTGGTGGACTGTTGCACGGATCCAGACGGGCGGGCTGTGGAC
CGGGCACGGGCCTGGTGCGAGATGGTCGGCATCCAGTACTTCAGATTGAACCCCCAGCTGGGGACGGACATCATGCTGGATGAGGTCAGT
GACACAGTGCTGGTCAACGCCCTCTGGGAGACCGAGGTCTACATCTATGAGCACCGCGAGGAGTTCCAGAAGCTCATCCAGCTGCTGCTC
TCACCCTGAGGGTCCCCAGCCTCTCACCGGCCCCAGCTGACCTCGTCCATTCAGCCCCTGCCAGGCCAAGCCCAGCCACTGCCCTCCCGG
GCAGATCTGGGCCCAGGCACCTCTGAGTCCATAGACCAGGCCTGGGAGAATGCCAAGCTGCCTGCCCGAGGCTGGTCCTGAAGGCCTGTC
TCCCACTAACCCCGCCTTCCAGCACTTTCTGTCATTCCAGGCTGGGAAAGTCTAGAGCCCCCTTTGGCCCCTTTCCCTGACTGTCAAGGA
CAACTGACTCCCCCATCAGCTCAAACATTAAGGGTACCCGGGCACAACCGTACCCCTGCCCCCAGCCCCAGCCTCCCTGAGGGCCTGCCG
GGCTGCCTCTGCCCCAGCCCCCAGCAAGGGCACTCCCAGGCTTCCTGGTGGGTGCAGCCCACTCCCTCTGCCCTCTGCTCCGTTCCCTGG
GGGCTGGGACTAAAGAAATGGGTGTCCCCCACCCCATCAGCTGGGAAAGCCCAGGCCGCAGGAGTGGGATGCCCGTTGGACTTTGCCCCT
CACACTGGCCCAGCCCCTCACACTGCCCCACCCCGAGAACCCTCAGCTCTCAAAGGTCACTCCTGGGAGTTTCTTCTTCCCAATGGAAGT

>19840_19840_5_CSNK1E-PLA2G6_CSNK1E_chr22_38689261_ENST00000403904_PLA2G6_chr22_38512218_ENST00000335539_length(amino acids)=416AA_BP=
MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLE
DLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLR
QLFRNLFHRQGFSYDYVFDWNMLKFGAARNPEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG

--------------------------------------------------------------
>19840_19840_6_CSNK1E-PLA2G6_CSNK1E_chr22_38689261_ENST00000403904_PLA2G6_chr22_38512218_ENST00000402064_length(transcript)=2920nt_BP=1580nt
CGGTGCGAGAGCGCGCGAGCCGGCGGCGGGGGCGGGCGGGCGGGCAGGAGGCCGGGAGGAGGGAGGCGGCGGCGGCGGCGGCGGCGGCGG
CGAGAGCCCAGAGCCAGAGCCCGGCCGGGGCCGAGCGGAGCGCGGCGGCGGCGGCGGCGGCGGCGGCTGGGCCGGGAGAGGCTGGCGCGC
CGGGCGGCTCCGCGAATCCTCCGGCATCCGCCCCGGCGGGCCGCCCCCGCCCGCGGCAGCCCCCCGAGCAGTGGCCCGGCATCGGCGCCT
TCCCGGCGGGCAAGAGTGAGCCATGGAGCTACGTGTGGGGAACAAGTACCGCCTGGGACGGAAGATCGGGAGCGGGTCCTTCGGAGATAT
CTACCTGGGTGCCAACATCGCCTCTGGTGAGGAAGTCGCCATCAAGCTGGAGTGTGTGAAGACAAAGCACCCCCAGCTGCACATCGAGAG
CAAGTTCTACAAGATGATGCAGGGTGGCGTGGGGATCCCGTCCATCAAGTGGTGCGGAGCTGAGGGCGACTACAACGTGATGGTCATGGA
GCTGCTGGGGCCTAGCCTCGAGGACCTGTTCAACTTCTGTTCCCGCAAATTCAGCCTCAAGACGGTGCTGCTCTTGGCCGACCAGATGAT
CAGCCGCATCGAGTATATCCACTCCAAGAACTTCATCCACCGGGACGTCAAGCCCGACAACTTCCTCATGGGGCTGGGGAAGAAGGGCAA
CCTGGTCTACATCATCGACTTCGGCCTGGCCAAGAAGTACCGGGACGCCCGCACCCACCAGCACATTCCCTACCGGGAAAACAAGAACCT
GACCGGCACGGCCCGCTACGCTTCCATCAACACGCACCTGGGCATTGAGCAAAGCCGTCGAGATGACCTGGAGAGCCTGGGCTACGTGCT
CATGTACTTCAACCTGGGCTCCCTGCCCTGGCAGGGGCTCAAAGCAGCCACCAAGCGCCAGAAGTATGAACGGATCAGCGAGAAGAAGAT
GTCAACGCCCATCGAGGTCCTCTGCAAAGGCTATCCCTCCGAATTCTCAACATACCTCAACTTCTGCCGCTCCCTGCGGTTTGACGACAA
GCCCGACTACTCTTACCTACGTCAGCTCTTCCGCAACCTCTTCCACCGGCAGGGCTTCTCCTATGACTACGTCTTTGACTGGAACATGCT
GAAATTCGGTGCAGCCCGGAATCCCGAGGATGTGGACCGGGAGCGGCGAGAACACGAACGCGAGGAGAGGATGGGGCAGCTACGGGGGTC
CGCGACCCGAGCCCTGCCCCCTGGCCCACCCACGGGGGCCACTGCCAACCGGCTCCGCAGTGCCGCCGAGCCCGTGGCTTCCACGCCAGC
CTCCCGCATCCAGCCGGCTGGCAATACTTCTCCCAGAGCGATCTCGCGGGTCGACCGGGAGAGGAAGGTGAGTATGAGGCTGCACAGGGG
TGCGCCCGCCAACGTCTCCTCCTCAGACCTCACTGGGCGGCAAGAGGTCTCCCGGATCCCAGCCTCACAGACAAGTGTGCCATTTGACCA
TCTCGGGAAGTGAGGAGAGCCCCCATTGGACCAGTGTTTGCTTAGGTGAGGGTGATGCTGACAGGGACACTGTCTGACCGGCAGCCGGCT
GAACTCCACCTCTTCCGGAACTACGATGCTCCAGAAACTGTCCGGGAGCCTCGTTTCAACCAGAACGTTAACCTCAGGCCTCCAGCTCAG
CCCTCAGACCAGCTGGTGTGGCGGGCGGCCCGAAGCAGCGGGGCAGCTCCTACTTACTTCCGACCCAATGGGCGCTTCCTGGACGGTGGG
CTGCTGGCCAACAACCCCACGCTGGATGCCATGACCGAGATCCATGAGTACAATCAGGACCTGATCCGCAAGGGTCAGGCCAACAAGGTG
AAGAAACTCTCCATCGTTGTCTCCCTGGGGACAGGGAGGTCCCCACAAGTGCCTGTGACCTGTGTGGATGTCTTCCGTCCCAGCAACCCC
TGGGAGCTGGCCAAGACTGTTTTTGGGGCCAAGGAACTGGGCAAGATGGTGGTGGACTGTTGCACGGATCCAGACGGGCGGGCTGTGGAC
CGGGCACGGGCCTGGTGCGAGATGGTCGGCATCCAGTACTTCAGATTGAACCCCCAGCTGGGGACGGACATCATGCTGGATGAGGTCAGT
GACACAGTGCTGGTCAACGCCCTCTGGGAGACCGAGGTCTACATCTATGAGCACCGCGAGGAGTTCCAGAAGCTCATCCAGCTGCTGCTC
TCACCCTGAGGGTCCCCAGCCTCTCACCGGCCCCAGCTGACCTCGTCCATTCAGCCCCTGCCAGGCCAAGCCCAGCCACTGCCCTCCCGG
GCAGATCTGGGCCCAGGCACCTCTGAGTCCATAGACCAGGCCTGGGAGAATGCCAAGCTGCCTGCCCGAGGCTGGTCCTGAAGGCCTGTC
TCCCACTAACCCCGCCTTCCAGCACTTTCTGTCATTCCAGGCTGGGAAAGTCTAGAGCCCCCTTTGGCCCCTTTCCCTGACTGTCAAGGA
CAACTGACTCCCCCATCAGCTCAAACATTAAGGGTACCCGGGCACAACCGTACCCCTGCCCCCAGCCCCAGCCTCCCTGAGGGCCTGCCG
GGCTGCCTCTGCCCCAGCCCCCAGCAAGGGCACTCCCAGGCTTCCTGGTGGGTGCAGCCCACTCCCTCTGCCCTCTGCTCCGTTCCCTGG
GGGCTGGGACTAAAGAAATGGGTGTCCCCCACCCCATCAGCTGGGAAAGCCCAGGCCGCAGGAGTGGGATGCCCGTTGGACTTTGCCCCT
CACACTGGCCCAGCCCCTCACACTGCCCCACCCCGAGAACCCTCAGCTCTCAAAGGTCACTCCTGGGAGTTTCTTCTTCCCAATGGAAGT

>19840_19840_6_CSNK1E-PLA2G6_CSNK1E_chr22_38689261_ENST00000403904_PLA2G6_chr22_38512218_ENST00000402064_length(amino acids)=416AA_BP=
MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLE
DLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLR
QLFRNLFHRQGFSYDYVFDWNMLKFGAARNPEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CSNK1E-PLA2G6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CSNK1E-PLA2G6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CSNK1E-PLA2G6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCSNK1EC0005586Bipolar Disorder5PSYGENET
HgeneCSNK1EC0036341Schizophrenia2PSYGENET
TgeneC0270724Infantile Neuroaxonal Dystrophy7CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC1857747NEURODEGENERATION WITH BRAIN IRON ACCUMULATION 2 (disorder)5CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneC2751842PARKINSON DISEASE 14, AUTOSOMAL RECESSIVE4CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC0005586Bipolar Disorder1PSYGENET
TgeneC0027960Nevus1CTD_human
TgeneC0033975Psychotic Disorders1PSYGENET
TgeneC0036341Schizophrenia1PSYGENET
TgeneC0349204Nonorganic psychosis1PSYGENET