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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CSNK1G3-CSNK1G3 (FusionGDB2 ID:HG1456TG1456)

Fusion Gene Summary for CSNK1G3-CSNK1G3

check button Fusion gene summary
Fusion gene informationFusion gene name: CSNK1G3-CSNK1G3
Fusion gene ID: hg1456tg1456
HgeneTgene
Gene symbol

CSNK1G3

CSNK1G3

Gene ID

1456

1456

Gene namecasein kinase 1 gamma 3casein kinase 1 gamma 3
SynonymsCKI-gamma 3|CSNK1G3LCKI-gamma 3|CSNK1G3L
Cytomap('CSNK1G3')('CSNK1G3')

5q23.2

5q23.2

Type of geneprotein-codingprotein-coding
Descriptioncasein kinase I isoform gamma-3casein kinase Icasein kinase I isoform gamma-3casein kinase I
Modification date2020031320200313
UniProtAcc

Q9Y6M4

Q9Y6M4

Ensembl transtripts involved in fusion geneENST00000345990, ENST00000360683, 
ENST00000361991, ENST00000395411, 
ENST00000395412, ENST00000510842, 
ENST00000521364, ENST00000512718, 
ENST00000508708, ENST00000511130, 
ENST00000345990, ENST00000360683, 
ENST00000361991, ENST00000395411, 
ENST00000395412, ENST00000510842, 
ENST00000521364, ENST00000508708, 
ENST00000511130, ENST00000512718, 
Fusion gene scores* DoF score4 X 6 X 2=487 X 7 X 5=245
# samples 69
** MAII scorelog2(6/48*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
log2(9/245*10)=-1.4447848426729
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CSNK1G3 [Title/Abstract] AND CSNK1G3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCSNK1G3(122950472)-CSNK1G3(122950490), # samples:1
CSNK1G3(122950454)-CSNK1G3(122950414), # samples:1
CSNK1G3(122893258)-CSNK1G3(122881109), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCSNK1G3

GO:0018105

peptidyl-serine phosphorylation

25500533

TgeneCSNK1G3

GO:0018105

peptidyl-serine phosphorylation

25500533



check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/AAA535640CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
ChiTaRS5.0N/AAW022209CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
ChiTaRS5.0N/AAW582006CSNK1G3chr5

122893258

+CSNK1G3chr5

122881109

+


Top

Fusion Gene ORF analysis for CSNK1G3-CSNK1G3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3UTRENST00000345990ENST00000345990CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000345990ENST00000345990CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000345990ENST00000360683CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000345990ENST00000360683CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000345990ENST00000361991CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000345990ENST00000361991CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000345990ENST00000395411CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000345990ENST00000395411CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000345990ENST00000395412CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000345990ENST00000395412CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000345990ENST00000510842CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000345990ENST00000510842CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000345990ENST00000521364CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000345990ENST00000521364CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000360683ENST00000345990CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000360683ENST00000345990CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000360683ENST00000360683CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000360683ENST00000360683CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000360683ENST00000361991CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000360683ENST00000361991CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000360683ENST00000395411CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000360683ENST00000395411CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000360683ENST00000395412CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000360683ENST00000395412CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000360683ENST00000510842CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000360683ENST00000510842CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000360683ENST00000521364CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000360683ENST00000521364CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000361991ENST00000345990CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000361991ENST00000345990CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000361991ENST00000360683CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000361991ENST00000360683CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000361991ENST00000361991CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000361991ENST00000361991CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000361991ENST00000395411CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000361991ENST00000395411CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000361991ENST00000395412CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000361991ENST00000395412CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000361991ENST00000510842CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000361991ENST00000510842CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000361991ENST00000521364CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000361991ENST00000521364CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000395411ENST00000345990CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000395411ENST00000345990CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000395411ENST00000360683CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000395411ENST00000360683CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000395411ENST00000361991CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000395411ENST00000361991CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000395411ENST00000395411CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000395411ENST00000395411CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000395411ENST00000395412CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000395411ENST00000395412CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000395411ENST00000510842CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000395411ENST00000510842CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000395411ENST00000521364CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000395411ENST00000521364CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000395412ENST00000345990CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000395412ENST00000345990CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000395412ENST00000360683CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000395412ENST00000360683CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000395412ENST00000361991CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000395412ENST00000361991CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000395412ENST00000395411CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000395412ENST00000395411CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000395412ENST00000395412CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000395412ENST00000395412CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000395412ENST00000510842CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000395412ENST00000510842CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000395412ENST00000521364CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000395412ENST00000521364CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000510842ENST00000345990CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000510842ENST00000345990CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000510842ENST00000360683CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000510842ENST00000360683CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000510842ENST00000361991CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000510842ENST00000361991CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000510842ENST00000395411CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000510842ENST00000395411CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000510842ENST00000395412CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000510842ENST00000395412CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000510842ENST00000510842CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000510842ENST00000510842CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000510842ENST00000521364CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000510842ENST00000521364CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000521364ENST00000345990CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000521364ENST00000345990CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000521364ENST00000360683CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000521364ENST00000360683CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000521364ENST00000361991CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000521364ENST00000361991CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000521364ENST00000395411CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000521364ENST00000395411CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000521364ENST00000395412CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000521364ENST00000395412CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000521364ENST00000510842CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000521364ENST00000510842CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-3UTRENST00000521364ENST00000521364CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-3UTRENST00000521364ENST00000521364CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000345990ENST00000508708CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000345990ENST00000508708CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000345990ENST00000511130CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000345990ENST00000511130CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000345990ENST00000512718CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000345990ENST00000512718CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000360683ENST00000508708CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000360683ENST00000508708CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000360683ENST00000511130CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000360683ENST00000511130CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000360683ENST00000512718CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000360683ENST00000512718CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000361991ENST00000508708CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000361991ENST00000508708CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000361991ENST00000511130CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000361991ENST00000511130CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000361991ENST00000512718CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000361991ENST00000512718CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000395411ENST00000508708CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000395411ENST00000508708CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000395411ENST00000511130CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000395411ENST00000511130CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000395411ENST00000512718CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000395411ENST00000512718CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000395412ENST00000508708CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000395412ENST00000508708CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000395412ENST00000511130CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000395412ENST00000511130CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000395412ENST00000512718CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000395412ENST00000512718CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000510842ENST00000508708CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000510842ENST00000508708CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000510842ENST00000511130CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000510842ENST00000511130CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000510842ENST00000512718CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000510842ENST00000512718CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000521364ENST00000508708CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000521364ENST00000508708CSNK1G3chr5

122950454

+CSNK1G3chr5

122950414

-
3UTR-intronENST00000521364ENST00000511130CSNK1G3chr5

122950472

+CSNK1G3chr5

122950490

-
3UTR-intronENST00000521364ENST00000511130CSNK1G3chr5

122950454

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122950454

+CSNK1G3chr5

122950414

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for CSNK1G3-CSNK1G3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CSNK1G3chr5122893258+CSNK1G3chr5122881108+2.65E-050.99997354
CSNK1G3chr5122893258+CSNK1G3chr5122881108+2.65E-050.99997354


check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CSNK1G3-CSNK1G3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:122950472/:122950490)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CSNK1G3

Q9Y6M4

CSNK1G3

Q9Y6M4

FUNCTION: Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity). {ECO:0000250}.FUNCTION: Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for CSNK1G3-CSNK1G3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for CSNK1G3-CSNK1G3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CSNK1G3-CSNK1G3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CSNK1G3-CSNK1G3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource