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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZFP90-CBFB (FusionGDB2 ID:HG146198TG865)

Fusion Gene Summary for ZFP90-CBFB

check button Fusion gene summary
Fusion gene informationFusion gene name: ZFP90-CBFB
Fusion gene ID: hg146198tg865
HgeneTgene
Gene symbol

ZFP90

CBFB

Gene ID

146198

865

Gene nameZFP90 zinc finger proteincore-binding factor subunit beta
SynonymsFIK|NK10|ZNF756|zfp-90PEBP2B
Cytomap('ZFP90')('CBFB')

16q22.1

16q22.1

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 90 homologFOXP3-interacting KRAB domain-containing proteinzinc finger protein 476zinc finger protein 756core-binding factor subunit betaCBF-betaPEA2-betaPEBP2-betaSL3-3 enhancer factor 1 beta subunitSL3-3 enhancer factor 1 subunit betaSL3/AKV core-binding factor beta subunitcore-binding factor beta subunitpolyomavirus enhancer binding protein 2, bet
Modification date2020031320200320
UniProtAcc.

Q13951

Ensembl transtripts involved in fusion geneENST00000398253, ENST00000563169, 
ENST00000564323, ENST00000570495, 
ENST00000570884, 
Fusion gene scores* DoF score10 X 9 X 8=7203 X 3 X 3=27
# samples 123
** MAII scorelog2(12/720*10)=-2.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: ZFP90 [Title/Abstract] AND CBFB [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZFP90(68573728)-CBFB(67116116), # samples:2
Anticipated loss of major functional domain due to fusion event.ZFP90-CBFB seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ZFP90-CBFB seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ZFP90 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CBFB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-WE-A8ZQ-06AZFP90chr16

68573728

+CBFBchr16

67116116

+


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Fusion Gene ORF analysis for ZFP90-CBFB

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000398253ENST00000568858ZFP90chr16

68573728

+CBFBchr16

67116116

+
5CDS-intronENST00000563169ENST00000568858ZFP90chr16

68573728

+CBFBchr16

67116116

+
5CDS-intronENST00000564323ENST00000568858ZFP90chr16

68573728

+CBFBchr16

67116116

+
5CDS-intronENST00000570495ENST00000568858ZFP90chr16

68573728

+CBFBchr16

67116116

+
In-frameENST00000398253ENST00000290858ZFP90chr16

68573728

+CBFBchr16

67116116

+
In-frameENST00000398253ENST00000412916ZFP90chr16

68573728

+CBFBchr16

67116116

+
In-frameENST00000398253ENST00000561924ZFP90chr16

68573728

+CBFBchr16

67116116

+
In-frameENST00000563169ENST00000290858ZFP90chr16

68573728

+CBFBchr16

67116116

+
In-frameENST00000563169ENST00000412916ZFP90chr16

68573728

+CBFBchr16

67116116

+
In-frameENST00000563169ENST00000561924ZFP90chr16

68573728

+CBFBchr16

67116116

+
In-frameENST00000564323ENST00000290858ZFP90chr16

68573728

+CBFBchr16

67116116

+
In-frameENST00000564323ENST00000412916ZFP90chr16

68573728

+CBFBchr16

67116116

+
In-frameENST00000564323ENST00000561924ZFP90chr16

68573728

+CBFBchr16

67116116

+
In-frameENST00000570495ENST00000290858ZFP90chr16

68573728

+CBFBchr16

67116116

+
In-frameENST00000570495ENST00000412916ZFP90chr16

68573728

+CBFBchr16

67116116

+
In-frameENST00000570495ENST00000561924ZFP90chr16

68573728

+CBFBchr16

67116116

+
intron-3CDSENST00000570884ENST00000290858ZFP90chr16

68573728

+CBFBchr16

67116116

+
intron-3CDSENST00000570884ENST00000412916ZFP90chr16

68573728

+CBFBchr16

67116116

+
intron-3CDSENST00000570884ENST00000561924ZFP90chr16

68573728

+CBFBchr16

67116116

+
intron-intronENST00000570884ENST00000568858ZFP90chr16

68573728

+CBFBchr16

67116116

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000570495ZFP90chr1668573728+ENST00000561924CBFBchr1667116116+5543257474155
ENST00000570495ZFP90chr1668573728+ENST00000290858CBFBchr1667116116+28013257474155
ENST00000570495ZFP90chr1668573728+ENST00000412916CBFBchr1667116116+27343257489160
ENST00000563169ZFP90chr1668573728+ENST00000561924CBFBchr1667116116+4932644051135
ENST00000563169ZFP90chr1668573728+ENST00000290858CBFBchr1667116116+27402644051135
ENST00000563169ZFP90chr1668573728+ENST00000412916CBFBchr1667116116+26732643372112
ENST00000564323ZFP90chr1668573728+ENST00000561924CBFBchr1667116116+47624710396128
ENST00000564323ZFP90chr1668573728+ENST00000290858CBFBchr1667116116+272324710396128
ENST00000564323ZFP90chr1668573728+ENST00000412916CBFBchr1667116116+265624710411133
ENST00000398253ZFP90chr1668573728+ENST00000561924CBFBchr1667116116+29768209070
ENST00000398253ZFP90chr1668573728+ENST00000290858CBFBchr1667116116+254468209070
ENST00000398253ZFP90chr1668573728+ENST00000412916CBFBchr1667116116+2477681512130369

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000570495ENST00000561924ZFP90chr1668573728+CBFBchr1667116116+0.16748320.8325168
ENST00000570495ENST00000290858ZFP90chr1668573728+CBFBchr1667116116+0.720444260.27955574
ENST00000570495ENST00000412916ZFP90chr1668573728+CBFBchr1667116116+0.323871730.67612827
ENST00000563169ENST00000561924ZFP90chr1668573728+CBFBchr1667116116+0.176469010.82353103
ENST00000563169ENST00000290858ZFP90chr1668573728+CBFBchr1667116116+0.369919360.6300807
ENST00000563169ENST00000412916ZFP90chr1668573728+CBFBchr1667116116+0.413723440.58627653
ENST00000564323ENST00000561924ZFP90chr1668573728+CBFBchr1667116116+0.229833740.7701663
ENST00000564323ENST00000290858ZFP90chr1668573728+CBFBchr1667116116+0.45172590.5482741
ENST00000564323ENST00000412916ZFP90chr1668573728+CBFBchr1667116116+0.73612070.2638793
ENST00000398253ENST00000561924ZFP90chr1668573728+CBFBchr1667116116+0.136275960.86372405
ENST00000398253ENST00000290858ZFP90chr1668573728+CBFBchr1667116116+0.70325060.29674935
ENST00000398253ENST00000412916ZFP90chr1668573728+CBFBchr1667116116+0.65753530.3424647

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Fusion Genomic Features for ZFP90-CBFB


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ZFP90chr1668573728+CBFBchr1667116115+2.20E-060.99999785
ZFP90chr1668573728+CBFBchr1667116115+2.20E-060.99999785

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ZFP90-CBFB


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:68573728/chr16:67116116)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CBFB

Q13951

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Forms the heterodimeric complex core-binding factor (CBF) with RUNX family proteins (RUNX1, RUNX2, and RUNX3). RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. The heterodimers bind to the core site of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters. CBF complexes repress ZBTB7B transcription factor during cytotoxic (CD8+) T cell development. They bind to RUNX-binding sequence within the ZBTB7B locus acting as transcriptional silencer and allowing for cytotoxic T cell differentiation. {ECO:0000250|UniProtKB:Q08024}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZFP90chr16:68573728chr16:67116116ENST00000398253+1414_8511637.0DomainKRAB
HgeneZFP90chr16:68573728chr16:67116116ENST00000563169+2514_8511637.0DomainKRAB
HgeneZFP90chr16:68573728chr16:67116116ENST00000570495+2514_8511637.0DomainKRAB
HgeneZFP90chr16:68573728chr16:67116116ENST00000398253+14211_23311637.0Zinc fingerC2H2-type 1
HgeneZFP90chr16:68573728chr16:67116116ENST00000398253+14254_27611637.0Zinc fingerC2H2-type 2
HgeneZFP90chr16:68573728chr16:67116116ENST00000398253+14282_30411637.0Zinc fingerC2H2-type 3
HgeneZFP90chr16:68573728chr16:67116116ENST00000398253+14310_33211637.0Zinc fingerC2H2-type 4
HgeneZFP90chr16:68573728chr16:67116116ENST00000398253+14338_36011637.0Zinc fingerC2H2-type 5
HgeneZFP90chr16:68573728chr16:67116116ENST00000398253+14366_38811637.0Zinc fingerC2H2-type 6
HgeneZFP90chr16:68573728chr16:67116116ENST00000398253+14394_41611637.0Zinc fingerC2H2-type 7
HgeneZFP90chr16:68573728chr16:67116116ENST00000398253+14450_47211637.0Zinc fingerC2H2-type 8
HgeneZFP90chr16:68573728chr16:67116116ENST00000398253+14497_51911637.0Zinc fingerC2H2-type 9
HgeneZFP90chr16:68573728chr16:67116116ENST00000398253+14525_54711637.0Zinc fingerC2H2-type 10
HgeneZFP90chr16:68573728chr16:67116116ENST00000398253+14553_57511637.0Zinc fingerC2H2-type 11
HgeneZFP90chr16:68573728chr16:67116116ENST00000398253+14581_60311637.0Zinc fingerC2H2-type 12
HgeneZFP90chr16:68573728chr16:67116116ENST00000398253+14609_63111637.0Zinc fingerC2H2-type 13
HgeneZFP90chr16:68573728chr16:67116116ENST00000563169+25211_23311637.0Zinc fingerC2H2-type 1
HgeneZFP90chr16:68573728chr16:67116116ENST00000563169+25254_27611637.0Zinc fingerC2H2-type 2
HgeneZFP90chr16:68573728chr16:67116116ENST00000563169+25282_30411637.0Zinc fingerC2H2-type 3
HgeneZFP90chr16:68573728chr16:67116116ENST00000563169+25310_33211637.0Zinc fingerC2H2-type 4
HgeneZFP90chr16:68573728chr16:67116116ENST00000563169+25338_36011637.0Zinc fingerC2H2-type 5
HgeneZFP90chr16:68573728chr16:67116116ENST00000563169+25366_38811637.0Zinc fingerC2H2-type 6
HgeneZFP90chr16:68573728chr16:67116116ENST00000563169+25394_41611637.0Zinc fingerC2H2-type 7
HgeneZFP90chr16:68573728chr16:67116116ENST00000563169+25450_47211637.0Zinc fingerC2H2-type 8
HgeneZFP90chr16:68573728chr16:67116116ENST00000563169+25497_51911637.0Zinc fingerC2H2-type 9
HgeneZFP90chr16:68573728chr16:67116116ENST00000563169+25525_54711637.0Zinc fingerC2H2-type 10
HgeneZFP90chr16:68573728chr16:67116116ENST00000563169+25553_57511637.0Zinc fingerC2H2-type 11
HgeneZFP90chr16:68573728chr16:67116116ENST00000563169+25581_60311637.0Zinc fingerC2H2-type 12
HgeneZFP90chr16:68573728chr16:67116116ENST00000563169+25609_63111637.0Zinc fingerC2H2-type 13
HgeneZFP90chr16:68573728chr16:67116116ENST00000570495+25211_23311637.0Zinc fingerC2H2-type 1
HgeneZFP90chr16:68573728chr16:67116116ENST00000570495+25254_27611637.0Zinc fingerC2H2-type 2
HgeneZFP90chr16:68573728chr16:67116116ENST00000570495+25282_30411637.0Zinc fingerC2H2-type 3
HgeneZFP90chr16:68573728chr16:67116116ENST00000570495+25310_33211637.0Zinc fingerC2H2-type 4
HgeneZFP90chr16:68573728chr16:67116116ENST00000570495+25338_36011637.0Zinc fingerC2H2-type 5
HgeneZFP90chr16:68573728chr16:67116116ENST00000570495+25366_38811637.0Zinc fingerC2H2-type 6
HgeneZFP90chr16:68573728chr16:67116116ENST00000570495+25394_41611637.0Zinc fingerC2H2-type 7
HgeneZFP90chr16:68573728chr16:67116116ENST00000570495+25450_47211637.0Zinc fingerC2H2-type 8
HgeneZFP90chr16:68573728chr16:67116116ENST00000570495+25497_51911637.0Zinc fingerC2H2-type 9
HgeneZFP90chr16:68573728chr16:67116116ENST00000570495+25525_54711637.0Zinc fingerC2H2-type 10
HgeneZFP90chr16:68573728chr16:67116116ENST00000570495+25553_57511637.0Zinc fingerC2H2-type 11
HgeneZFP90chr16:68573728chr16:67116116ENST00000570495+25581_60311637.0Zinc fingerC2H2-type 12
HgeneZFP90chr16:68573728chr16:67116116ENST00000570495+25609_63111637.0Zinc fingerC2H2-type 13


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Fusion Gene Sequence for ZFP90-CBFB


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>101085_101085_1_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000398253_CBFB_chr16_67116116_ENST00000290858_length(transcript)=2544nt_BP=68nt
CTCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAAC
AGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGC
TGCTGGCAGTAACTGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATA
GCACAGCAGATGTGTGCTGCCCATCTTTACATACACATTGCTTCTAGTTGGCAGAAATAATTGATTAAAAGACCAGAAACTGTGATAACT
GGAGGTACTACGGTCTATTTCTCAACCTTAGGCAGTAATAGACATCACAAACTGCCATGGTTTTGCACTATGATTATAATACCTGCATTT
CTAATTTTTTAAGCATGTAGCCAGTAATAATTTGAAGTTTTTTTTCTATGCAAGCTTACCTTGTTGGCATTATTTTAGGGAGTTGAAACT
ATCAACTGTAAAGCTCCTTTTCTTCCACTTTAATTTAAAAGTTCATGTCATTTAAAAACAAGTCAAGAAATTAAAATTGTATCAGAGGGT
TTTCTCTAATCATTTTTTCTATTTTTTTTTTTGTACTTCTAGATGTTTTGGTTATACAGCTTCATTTTAGATGAGCATTCTTATTTTTTG
TTTTGTTTGCCCCATTTCCTTTTGTGTTTTTATAGTCTATAGCATTTTAAAACTGCTGATGTTGTTTGCATTATTTACAGGCTAAAAACT
TAGTAGCATAGAGCTGTCTGCCACAGCCTTCTGACAAAGTTTACAGTTATTAAAGTTGCAGTATCCTTTTAAATGCTAGTAATCAGCACT
CTTTCTTTTTTTTTTTTTTAATAGAGACAGGGTCTCGCAGTGTTGCCCAGGCTGGTCTCGAACTCCTGGCATCAAGCGATCCTCCTGCCT
TAGCCTCCCAGAGTACTGGGATTACAGGCTCTTTCTTTTTAAACATAAAAGTTTTAAATTGGTATTAACTCTGTACTCTGCCCTAGATTG
TTTTAGCTTCTGTTCTGTAATCATGAGTTTGGTTGGAGATATTCTCCATAGATGATCTTCTACTGAAATGCCTAAAGAAGTCACAGGCTG
GCTTCTGTTTTATTCAGGGATTTTTTTAAAAAGTCAATCAGAAAAGGGATACTGGAGCTTCTTCATGTATGTAACAGCATATTAAACTGG
AGACAGTGATGAATCAGCTACAAAGGTAATATTGTATTAAAATCATGTTTAAGATAGCTGCTTTTATGTGTATTTTATATTGCATGCTTT
TGTAAAAACATGCTGGGTGATGAAAGATTAGTTTTAGAGAGAAAATGTTCATCTGTGCAGAGGATGCATTTTCTTCCATTAATTCTGGAA
AAAACGTTCACAGTTATATATATGGTATTTTGCAAAAGGACTATTAATAGAACCTTTTGAGATGAATTAATGTAAGAATATTTTTTAAAT
AGGCTTACTGTCAAATTGCAACTTTTTTTTTAGATACAGAGTGGAAAACAGTGCTAAGTCATTTGGCACCTCCTTACAAATATTTTTCAT
GGTCACATTTATTAAATGTTACTACATTTCTGAATTTTTGAAAAATGTATTTTATCATTAAATGGCATTATTTTAAAGGGTGAAAAACTG
ACACAGTCAATTCAGAAAATGGACTGAAGTCTGAATAAGGTCATTGCATTTAAAAAGCATATAACTGTACTTGACTGATGAGGGAGGTGT
TACTTTCATTGTATATAGGTCTTATTTCATAAACAGATATCCTGTATCAAATAAAAGTATTTGTTATATATTTGAAGTTATGCATGGAAA
GGAGTGTGTTTAAATTGTTACAAACAATAATGCGTCATTAAAGGCCATGCTGATCTTGCATAACTATAAGTACTATGAATGAATTTGGTT
GGTTTTGGTGTTGTACAGCTCACATGTTTACACACTCAGTGCCCTAATTTCCCCTGAGGGAATCGCTTTTTAAGTGATCCTTACAGTGGT
GTTTTATGTTACTTTATTACAGAGCTCCTTGGTTTTTTACTTCTGCACTTAAATTTTTTTAAATAACATGATGATGGTACATTTTCCTCT
ATTGTCTAGCTAAGGGCTTTCGGTCCACCAGTAAATAAGATCAAATGCTCTTAAATGTTCCTGTTACCATCCTAATGTAAATACTGGATT
TTTCTGTCATTTAGCACCATGCTGCTTCTGTCTGTCTTAATGCTGGCATTAAGATCATGAGCCCTTTTTCTCCAGTAGTACAGGCTTTGA
AAACTACTTCTATTAAGTTATTGATGCAATTTGATATTTTTTCATAATCTATATTTAAACAAAATTACATCATTGCATCATCTTTTCTAA
ATTCATCTCCATTAAAACTTGCCTTAAGCTACCAGATTGCTTTTGCCACCATTGGCCATACTGTGTGTTTGTTTGTTTAATTTACTTTCA

>101085_101085_1_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000398253_CBFB_chr16_67116116_ENST00000290858_length(amino acids)=70AA_BP=5

--------------------------------------------------------------
>101085_101085_2_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000398253_CBFB_chr16_67116116_ENST00000412916_length(transcript)=2477nt_BP=68nt
CTCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAAC
AGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGCAAGAAGACAACAAG
ACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATAGCACAGCAGATGTGTGCTGCCCATCTTTACA
TACACATTGCTTCTAGTTGGCAGAAATAATTGATTAAAAGACCAGAAACTGTGATAACTGGAGGTACTACGGTCTATTTCTCAACCTTAG
GCAGTAATAGACATCACAAACTGCCATGGTTTTGCACTATGATTATAATACCTGCATTTCTAATTTTTTAAGCATGTAGCCAGTAATAAT
TTGAAGTTTTTTTTCTATGCAAGCTTACCTTGTTGGCATTATTTTAGGGAGTTGAAACTATCAACTGTAAAGCTCCTTTTCTTCCACTTT
AATTTAAAAGTTCATGTCATTTAAAAACAAGTCAAGAAATTAAAATTGTATCAGAGGGTTTTCTCTAATCATTTTTTCTATTTTTTTTTT
TGTACTTCTAGATGTTTTGGTTATACAGCTTCATTTTAGATGAGCATTCTTATTTTTTGTTTTGTTTGCCCCATTTCCTTTTGTGTTTTT
ATAGTCTATAGCATTTTAAAACTGCTGATGTTGTTTGCATTATTTACAGGCTAAAAACTTAGTAGCATAGAGCTGTCTGCCACAGCCTTC
TGACAAAGTTTACAGTTATTAAAGTTGCAGTATCCTTTTAAATGCTAGTAATCAGCACTCTTTCTTTTTTTTTTTTTTAATAGAGACAGG
GTCTCGCAGTGTTGCCCAGGCTGGTCTCGAACTCCTGGCATCAAGCGATCCTCCTGCCTTAGCCTCCCAGAGTACTGGGATTACAGGCTC
TTTCTTTTTAAACATAAAAGTTTTAAATTGGTATTAACTCTGTACTCTGCCCTAGATTGTTTTAGCTTCTGTTCTGTAATCATGAGTTTG
GTTGGAGATATTCTCCATAGATGATCTTCTACTGAAATGCCTAAAGAAGTCACAGGCTGGCTTCTGTTTTATTCAGGGATTTTTTTAAAA
AGTCAATCAGAAAAGGGATACTGGAGCTTCTTCATGTATGTAACAGCATATTAAACTGGAGACAGTGATGAATCAGCTACAAAGGTAATA
TTGTATTAAAATCATGTTTAAGATAGCTGCTTTTATGTGTATTTTATATTGCATGCTTTTGTAAAAACATGCTGGGTGATGAAAGATTAG
TTTTAGAGAGAAAATGTTCATCTGTGCAGAGGATGCATTTTCTTCCATTAATTCTGGAAAAAACGTTCACAGTTATATATATGGTATTTT
GCAAAAGGACTATTAATAGAACCTTTTGAGATGAATTAATGTAAGAATATTTTTTAAATAGGCTTACTGTCAAATTGCAACTTTTTTTTT
AGATACAGAGTGGAAAACAGTGCTAAGTCATTTGGCACCTCCTTACAAATATTTTTCATGGTCACATTTATTAAATGTTACTACATTTCT
GAATTTTTGAAAAATGTATTTTATCATTAAATGGCATTATTTTAAAGGGTGAAAAACTGACACAGTCAATTCAGAAAATGGACTGAAGTC
TGAATAAGGTCATTGCATTTAAAAAGCATATAACTGTACTTGACTGATGAGGGAGGTGTTACTTTCATTGTATATAGGTCTTATTTCATA
AACAGATATCCTGTATCAAATAAAAGTATTTGTTATATATTTGAAGTTATGCATGGAAAGGAGTGTGTTTAAATTGTTACAAACAATAAT
GCGTCATTAAAGGCCATGCTGATCTTGCATAACTATAAGTACTATGAATGAATTTGGTTGGTTTTGGTGTTGTACAGCTCACATGTTTAC
ACACTCAGTGCCCTAATTTCCCCTGAGGGAATCGCTTTTTAAGTGATCCTTACAGTGGTGTTTTATGTTACTTTATTACAGAGCTCCTTG
GTTTTTTACTTCTGCACTTAAATTTTTTTAAATAACATGATGATGGTACATTTTCCTCTATTGTCTAGCTAAGGGCTTTCGGTCCACCAG
TAAATAAGATCAAATGCTCTTAAATGTTCCTGTTACCATCCTAATGTAAATACTGGATTTTTCTGTCATTTAGCACCATGCTGCTTCTGT
CTGTCTTAATGCTGGCATTAAGATCATGAGCCCTTTTTCTCCAGTAGTACAGGCTTTGAAAACTACTTCTATTAAGTTATTGATGCAATT
TGATATTTTTTCATAATCTATATTTAAACAAAATTACATCATTGCATCATCTTTTCTAAATTCATCTCCATTAAAACTTGCCTTAAGCTA

>101085_101085_2_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000398253_CBFB_chr16_67116116_ENST00000412916_length(amino acids)=69AA_BP=

--------------------------------------------------------------
>101085_101085_3_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000398253_CBFB_chr16_67116116_ENST00000561924_length(transcript)=297nt_BP=68nt
CTCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAAC
AGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGC
TGCTGGCAGTAACTGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATA

>101085_101085_3_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000398253_CBFB_chr16_67116116_ENST00000561924_length(amino acids)=70AA_BP=5

--------------------------------------------------------------
>101085_101085_4_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000563169_CBFB_chr16_67116116_ENST00000290858_length(transcript)=2740nt_BP=264nt
CAGGCGCACTTCCAGTTCTGCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCA
GAATTGGAGATAACCGAGGCTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCA
GAGGCGGTGATTCTGACTCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAG
GATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAG
GTGAGAGTTTCACAGCTGCTGGCAGTAACTGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAA
ACTTCGTTAATTAATAGCACAGCAGATGTGTGCTGCCCATCTTTACATACACATTGCTTCTAGTTGGCAGAAATAATTGATTAAAAGACC
AGAAACTGTGATAACTGGAGGTACTACGGTCTATTTCTCAACCTTAGGCAGTAATAGACATCACAAACTGCCATGGTTTTGCACTATGAT
TATAATACCTGCATTTCTAATTTTTTAAGCATGTAGCCAGTAATAATTTGAAGTTTTTTTTCTATGCAAGCTTACCTTGTTGGCATTATT
TTAGGGAGTTGAAACTATCAACTGTAAAGCTCCTTTTCTTCCACTTTAATTTAAAAGTTCATGTCATTTAAAAACAAGTCAAGAAATTAA
AATTGTATCAGAGGGTTTTCTCTAATCATTTTTTCTATTTTTTTTTTTGTACTTCTAGATGTTTTGGTTATACAGCTTCATTTTAGATGA
GCATTCTTATTTTTTGTTTTGTTTGCCCCATTTCCTTTTGTGTTTTTATAGTCTATAGCATTTTAAAACTGCTGATGTTGTTTGCATTAT
TTACAGGCTAAAAACTTAGTAGCATAGAGCTGTCTGCCACAGCCTTCTGACAAAGTTTACAGTTATTAAAGTTGCAGTATCCTTTTAAAT
GCTAGTAATCAGCACTCTTTCTTTTTTTTTTTTTTAATAGAGACAGGGTCTCGCAGTGTTGCCCAGGCTGGTCTCGAACTCCTGGCATCA
AGCGATCCTCCTGCCTTAGCCTCCCAGAGTACTGGGATTACAGGCTCTTTCTTTTTAAACATAAAAGTTTTAAATTGGTATTAACTCTGT
ACTCTGCCCTAGATTGTTTTAGCTTCTGTTCTGTAATCATGAGTTTGGTTGGAGATATTCTCCATAGATGATCTTCTACTGAAATGCCTA
AAGAAGTCACAGGCTGGCTTCTGTTTTATTCAGGGATTTTTTTAAAAAGTCAATCAGAAAAGGGATACTGGAGCTTCTTCATGTATGTAA
CAGCATATTAAACTGGAGACAGTGATGAATCAGCTACAAAGGTAATATTGTATTAAAATCATGTTTAAGATAGCTGCTTTTATGTGTATT
TTATATTGCATGCTTTTGTAAAAACATGCTGGGTGATGAAAGATTAGTTTTAGAGAGAAAATGTTCATCTGTGCAGAGGATGCATTTTCT
TCCATTAATTCTGGAAAAAACGTTCACAGTTATATATATGGTATTTTGCAAAAGGACTATTAATAGAACCTTTTGAGATGAATTAATGTA
AGAATATTTTTTAAATAGGCTTACTGTCAAATTGCAACTTTTTTTTTAGATACAGAGTGGAAAACAGTGCTAAGTCATTTGGCACCTCCT
TACAAATATTTTTCATGGTCACATTTATTAAATGTTACTACATTTCTGAATTTTTGAAAAATGTATTTTATCATTAAATGGCATTATTTT
AAAGGGTGAAAAACTGACACAGTCAATTCAGAAAATGGACTGAAGTCTGAATAAGGTCATTGCATTTAAAAAGCATATAACTGTACTTGA
CTGATGAGGGAGGTGTTACTTTCATTGTATATAGGTCTTATTTCATAAACAGATATCCTGTATCAAATAAAAGTATTTGTTATATATTTG
AAGTTATGCATGGAAAGGAGTGTGTTTAAATTGTTACAAACAATAATGCGTCATTAAAGGCCATGCTGATCTTGCATAACTATAAGTACT
ATGAATGAATTTGGTTGGTTTTGGTGTTGTACAGCTCACATGTTTACACACTCAGTGCCCTAATTTCCCCTGAGGGAATCGCTTTTTAAG
TGATCCTTACAGTGGTGTTTTATGTTACTTTATTACAGAGCTCCTTGGTTTTTTACTTCTGCACTTAAATTTTTTTAAATAACATGATGA
TGGTACATTTTCCTCTATTGTCTAGCTAAGGGCTTTCGGTCCACCAGTAAATAAGATCAAATGCTCTTAAATGTTCCTGTTACCATCCTA
ATGTAAATACTGGATTTTTCTGTCATTTAGCACCATGCTGCTTCTGTCTGTCTTAATGCTGGCATTAAGATCATGAGCCCTTTTTCTCCA
GTAGTACAGGCTTTGAAAACTACTTCTATTAAGTTATTGATGCAATTTGATATTTTTTCATAATCTATATTTAAACAAAATTACATCATT
GCATCATCTTTTCTAAATTCATCTCCATTAAAACTTGCCTTAAGCTACCAGATTGCTTTTGCCACCATTGGCCATACTGTGTGTTTGTTT

>101085_101085_4_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000563169_CBFB_chr16_67116116_ENST00000290858_length(amino acids)=135AA_BP=5
MLSSCQLLPAAVKLSPPFPPDETCLYLQIRVSFSEPLQRPVVLMHPPAGARRSEASGPFLPRQGPAPGQESESPPLGGSGFRDLRPTQSL

--------------------------------------------------------------
>101085_101085_5_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000563169_CBFB_chr16_67116116_ENST00000412916_length(transcript)=2673nt_BP=264nt
CAGGCGCACTTCCAGTTCTGCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCA
GAATTGGAGATAACCGAGGCTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCA
GAGGCGGTGATTCTGACTCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAG
GATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAG
GCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATAGCACAGCAGATGTGT
GCTGCCCATCTTTACATACACATTGCTTCTAGTTGGCAGAAATAATTGATTAAAAGACCAGAAACTGTGATAACTGGAGGTACTACGGTC
TATTTCTCAACCTTAGGCAGTAATAGACATCACAAACTGCCATGGTTTTGCACTATGATTATAATACCTGCATTTCTAATTTTTTAAGCA
TGTAGCCAGTAATAATTTGAAGTTTTTTTTCTATGCAAGCTTACCTTGTTGGCATTATTTTAGGGAGTTGAAACTATCAACTGTAAAGCT
CCTTTTCTTCCACTTTAATTTAAAAGTTCATGTCATTTAAAAACAAGTCAAGAAATTAAAATTGTATCAGAGGGTTTTCTCTAATCATTT
TTTCTATTTTTTTTTTTGTACTTCTAGATGTTTTGGTTATACAGCTTCATTTTAGATGAGCATTCTTATTTTTTGTTTTGTTTGCCCCAT
TTCCTTTTGTGTTTTTATAGTCTATAGCATTTTAAAACTGCTGATGTTGTTTGCATTATTTACAGGCTAAAAACTTAGTAGCATAGAGCT
GTCTGCCACAGCCTTCTGACAAAGTTTACAGTTATTAAAGTTGCAGTATCCTTTTAAATGCTAGTAATCAGCACTCTTTCTTTTTTTTTT
TTTTAATAGAGACAGGGTCTCGCAGTGTTGCCCAGGCTGGTCTCGAACTCCTGGCATCAAGCGATCCTCCTGCCTTAGCCTCCCAGAGTA
CTGGGATTACAGGCTCTTTCTTTTTAAACATAAAAGTTTTAAATTGGTATTAACTCTGTACTCTGCCCTAGATTGTTTTAGCTTCTGTTC
TGTAATCATGAGTTTGGTTGGAGATATTCTCCATAGATGATCTTCTACTGAAATGCCTAAAGAAGTCACAGGCTGGCTTCTGTTTTATTC
AGGGATTTTTTTAAAAAGTCAATCAGAAAAGGGATACTGGAGCTTCTTCATGTATGTAACAGCATATTAAACTGGAGACAGTGATGAATC
AGCTACAAAGGTAATATTGTATTAAAATCATGTTTAAGATAGCTGCTTTTATGTGTATTTTATATTGCATGCTTTTGTAAAAACATGCTG
GGTGATGAAAGATTAGTTTTAGAGAGAAAATGTTCATCTGTGCAGAGGATGCATTTTCTTCCATTAATTCTGGAAAAAACGTTCACAGTT
ATATATATGGTATTTTGCAAAAGGACTATTAATAGAACCTTTTGAGATGAATTAATGTAAGAATATTTTTTAAATAGGCTTACTGTCAAA
TTGCAACTTTTTTTTTAGATACAGAGTGGAAAACAGTGCTAAGTCATTTGGCACCTCCTTACAAATATTTTTCATGGTCACATTTATTAA
ATGTTACTACATTTCTGAATTTTTGAAAAATGTATTTTATCATTAAATGGCATTATTTTAAAGGGTGAAAAACTGACACAGTCAATTCAG
AAAATGGACTGAAGTCTGAATAAGGTCATTGCATTTAAAAAGCATATAACTGTACTTGACTGATGAGGGAGGTGTTACTTTCATTGTATA
TAGGTCTTATTTCATAAACAGATATCCTGTATCAAATAAAAGTATTTGTTATATATTTGAAGTTATGCATGGAAAGGAGTGTGTTTAAAT
TGTTACAAACAATAATGCGTCATTAAAGGCCATGCTGATCTTGCATAACTATAAGTACTATGAATGAATTTGGTTGGTTTTGGTGTTGTA
CAGCTCACATGTTTACACACTCAGTGCCCTAATTTCCCCTGAGGGAATCGCTTTTTAAGTGATCCTTACAGTGGTGTTTTATGTTACTTT
ATTACAGAGCTCCTTGGTTTTTTACTTCTGCACTTAAATTTTTTTAAATAACATGATGATGGTACATTTTCCTCTATTGTCTAGCTAAGG
GCTTTCGGTCCACCAGTAAATAAGATCAAATGCTCTTAAATGTTCCTGTTACCATCCTAATGTAAATACTGGATTTTTCTGTCATTTAGC
ACCATGCTGCTTCTGTCTGTCTTAATGCTGGCATTAAGATCATGAGCCCTTTTTCTCCAGTAGTACAGGCTTTGAAAACTACTTCTATTA
AGTTATTGATGCAATTTGATATTTTTTCATAATCTATATTTAAACAAAATTACATCATTGCATCATCTTTTCTAAATTCATCTCCATTAA

>101085_101085_5_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000563169_CBFB_chr16_67116116_ENST00000412916_length(amino acids)=112AA_BP=1
MSLSSNSRVLLRASSKACCANASSCWGAAVGGLGAIPASPGPGSGAGVRITASGGLRISRPPAHPEPRAAPPAPAEASVISNSDLRRGCP

--------------------------------------------------------------
>101085_101085_6_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000563169_CBFB_chr16_67116116_ENST00000561924_length(transcript)=493nt_BP=264nt
CAGGCGCACTTCCAGTTCTGCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCA
GAATTGGAGATAACCGAGGCTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCA
GAGGCGGTGATTCTGACTCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAG
GATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAG
GTGAGAGTTTCACAGCTGCTGGCAGTAACTGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAA

>101085_101085_6_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000563169_CBFB_chr16_67116116_ENST00000561924_length(amino acids)=135AA_BP=5
MLSSCQLLPAAVKLSPPFPPDETCLYLQIRVSFSEPLQRPVVLMHPPAGARRSEASGPFLPRQGPAPGQESESPPLGGSGFRDLRPTQSL

--------------------------------------------------------------
>101085_101085_7_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000564323_CBFB_chr16_67116116_ENST00000290858_length(transcript)=2723nt_BP=247nt
ACTTCCAGTTCTGCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCAGAATTGG
AGATAACCGAGGCTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCAGAGGCGC
TCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACA
GGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGCT
GCTGGCAGTAACTGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATAG
CACAGCAGATGTGTGCTGCCCATCTTTACATACACATTGCTTCTAGTTGGCAGAAATAATTGATTAAAAGACCAGAAACTGTGATAACTG
GAGGTACTACGGTCTATTTCTCAACCTTAGGCAGTAATAGACATCACAAACTGCCATGGTTTTGCACTATGATTATAATACCTGCATTTC
TAATTTTTTAAGCATGTAGCCAGTAATAATTTGAAGTTTTTTTTCTATGCAAGCTTACCTTGTTGGCATTATTTTAGGGAGTTGAAACTA
TCAACTGTAAAGCTCCTTTTCTTCCACTTTAATTTAAAAGTTCATGTCATTTAAAAACAAGTCAAGAAATTAAAATTGTATCAGAGGGTT
TTCTCTAATCATTTTTTCTATTTTTTTTTTTGTACTTCTAGATGTTTTGGTTATACAGCTTCATTTTAGATGAGCATTCTTATTTTTTGT
TTTGTTTGCCCCATTTCCTTTTGTGTTTTTATAGTCTATAGCATTTTAAAACTGCTGATGTTGTTTGCATTATTTACAGGCTAAAAACTT
AGTAGCATAGAGCTGTCTGCCACAGCCTTCTGACAAAGTTTACAGTTATTAAAGTTGCAGTATCCTTTTAAATGCTAGTAATCAGCACTC
TTTCTTTTTTTTTTTTTTAATAGAGACAGGGTCTCGCAGTGTTGCCCAGGCTGGTCTCGAACTCCTGGCATCAAGCGATCCTCCTGCCTT
AGCCTCCCAGAGTACTGGGATTACAGGCTCTTTCTTTTTAAACATAAAAGTTTTAAATTGGTATTAACTCTGTACTCTGCCCTAGATTGT
TTTAGCTTCTGTTCTGTAATCATGAGTTTGGTTGGAGATATTCTCCATAGATGATCTTCTACTGAAATGCCTAAAGAAGTCACAGGCTGG
CTTCTGTTTTATTCAGGGATTTTTTTAAAAAGTCAATCAGAAAAGGGATACTGGAGCTTCTTCATGTATGTAACAGCATATTAAACTGGA
GACAGTGATGAATCAGCTACAAAGGTAATATTGTATTAAAATCATGTTTAAGATAGCTGCTTTTATGTGTATTTTATATTGCATGCTTTT
GTAAAAACATGCTGGGTGATGAAAGATTAGTTTTAGAGAGAAAATGTTCATCTGTGCAGAGGATGCATTTTCTTCCATTAATTCTGGAAA
AAACGTTCACAGTTATATATATGGTATTTTGCAAAAGGACTATTAATAGAACCTTTTGAGATGAATTAATGTAAGAATATTTTTTAAATA
GGCTTACTGTCAAATTGCAACTTTTTTTTTAGATACAGAGTGGAAAACAGTGCTAAGTCATTTGGCACCTCCTTACAAATATTTTTCATG
GTCACATTTATTAAATGTTACTACATTTCTGAATTTTTGAAAAATGTATTTTATCATTAAATGGCATTATTTTAAAGGGTGAAAAACTGA
CACAGTCAATTCAGAAAATGGACTGAAGTCTGAATAAGGTCATTGCATTTAAAAAGCATATAACTGTACTTGACTGATGAGGGAGGTGTT
ACTTTCATTGTATATAGGTCTTATTTCATAAACAGATATCCTGTATCAAATAAAAGTATTTGTTATATATTTGAAGTTATGCATGGAAAG
GAGTGTGTTTAAATTGTTACAAACAATAATGCGTCATTAAAGGCCATGCTGATCTTGCATAACTATAAGTACTATGAATGAATTTGGTTG
GTTTTGGTGTTGTACAGCTCACATGTTTACACACTCAGTGCCCTAATTTCCCCTGAGGGAATCGCTTTTTAAGTGATCCTTACAGTGGTG
TTTTATGTTACTTTATTACAGAGCTCCTTGGTTTTTTACTTCTGCACTTAAATTTTTTTAAATAACATGATGATGGTACATTTTCCTCTA
TTGTCTAGCTAAGGGCTTTCGGTCCACCAGTAAATAAGATCAAATGCTCTTAAATGTTCCTGTTACCATCCTAATGTAAATACTGGATTT
TTCTGTCATTTAGCACCATGCTGCTTCTGTCTGTCTTAATGCTGGCATTAAGATCATGAGCCCTTTTTCTCCAGTAGTACAGGCTTTGAA
AACTACTTCTATTAAGTTATTGATGCAATTTGATATTTTTTCATAATCTATATTTAAACAAAATTACATCATTGCATCATCTTTTCTAAA
TTCATCTCCATTAAAACTTGCCTTAAGCTACCAGATTGCTTTTGCCACCATTGGCCATACTGTGTGTTTGTTTGTTTAATTTACTTTCAC

>101085_101085_7_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000564323_CBFB_chr16_67116116_ENST00000290858_length(amino acids)=128AA_BP=78
MPHRCGHCPTPVRLRPLWAAPPQIRIGDNRGFGGGGRSCPRLWVGRRSRNPEPPRGAPAPEPGPGEAGMAPRPPTAAPQQEDALAQQAFE

--------------------------------------------------------------
>101085_101085_8_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000564323_CBFB_chr16_67116116_ENST00000412916_length(transcript)=2656nt_BP=247nt
ACTTCCAGTTCTGCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCAGAATTGG
AGATAACCGAGGCTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCAGAGGCGC
TCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACA
GGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGCAAGAAGACAACAAGA
CCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATAGCACAGCAGATGTGTGCTGCCCATCTTTACAT
ACACATTGCTTCTAGTTGGCAGAAATAATTGATTAAAAGACCAGAAACTGTGATAACTGGAGGTACTACGGTCTATTTCTCAACCTTAGG
CAGTAATAGACATCACAAACTGCCATGGTTTTGCACTATGATTATAATACCTGCATTTCTAATTTTTTAAGCATGTAGCCAGTAATAATT
TGAAGTTTTTTTTCTATGCAAGCTTACCTTGTTGGCATTATTTTAGGGAGTTGAAACTATCAACTGTAAAGCTCCTTTTCTTCCACTTTA
ATTTAAAAGTTCATGTCATTTAAAAACAAGTCAAGAAATTAAAATTGTATCAGAGGGTTTTCTCTAATCATTTTTTCTATTTTTTTTTTT
GTACTTCTAGATGTTTTGGTTATACAGCTTCATTTTAGATGAGCATTCTTATTTTTTGTTTTGTTTGCCCCATTTCCTTTTGTGTTTTTA
TAGTCTATAGCATTTTAAAACTGCTGATGTTGTTTGCATTATTTACAGGCTAAAAACTTAGTAGCATAGAGCTGTCTGCCACAGCCTTCT
GACAAAGTTTACAGTTATTAAAGTTGCAGTATCCTTTTAAATGCTAGTAATCAGCACTCTTTCTTTTTTTTTTTTTTAATAGAGACAGGG
TCTCGCAGTGTTGCCCAGGCTGGTCTCGAACTCCTGGCATCAAGCGATCCTCCTGCCTTAGCCTCCCAGAGTACTGGGATTACAGGCTCT
TTCTTTTTAAACATAAAAGTTTTAAATTGGTATTAACTCTGTACTCTGCCCTAGATTGTTTTAGCTTCTGTTCTGTAATCATGAGTTTGG
TTGGAGATATTCTCCATAGATGATCTTCTACTGAAATGCCTAAAGAAGTCACAGGCTGGCTTCTGTTTTATTCAGGGATTTTTTTAAAAA
GTCAATCAGAAAAGGGATACTGGAGCTTCTTCATGTATGTAACAGCATATTAAACTGGAGACAGTGATGAATCAGCTACAAAGGTAATAT
TGTATTAAAATCATGTTTAAGATAGCTGCTTTTATGTGTATTTTATATTGCATGCTTTTGTAAAAACATGCTGGGTGATGAAAGATTAGT
TTTAGAGAGAAAATGTTCATCTGTGCAGAGGATGCATTTTCTTCCATTAATTCTGGAAAAAACGTTCACAGTTATATATATGGTATTTTG
CAAAAGGACTATTAATAGAACCTTTTGAGATGAATTAATGTAAGAATATTTTTTAAATAGGCTTACTGTCAAATTGCAACTTTTTTTTTA
GATACAGAGTGGAAAACAGTGCTAAGTCATTTGGCACCTCCTTACAAATATTTTTCATGGTCACATTTATTAAATGTTACTACATTTCTG
AATTTTTGAAAAATGTATTTTATCATTAAATGGCATTATTTTAAAGGGTGAAAAACTGACACAGTCAATTCAGAAAATGGACTGAAGTCT
GAATAAGGTCATTGCATTTAAAAAGCATATAACTGTACTTGACTGATGAGGGAGGTGTTACTTTCATTGTATATAGGTCTTATTTCATAA
ACAGATATCCTGTATCAAATAAAAGTATTTGTTATATATTTGAAGTTATGCATGGAAAGGAGTGTGTTTAAATTGTTACAAACAATAATG
CGTCATTAAAGGCCATGCTGATCTTGCATAACTATAAGTACTATGAATGAATTTGGTTGGTTTTGGTGTTGTACAGCTCACATGTTTACA
CACTCAGTGCCCTAATTTCCCCTGAGGGAATCGCTTTTTAAGTGATCCTTACAGTGGTGTTTTATGTTACTTTATTACAGAGCTCCTTGG
TTTTTTACTTCTGCACTTAAATTTTTTTAAATAACATGATGATGGTACATTTTCCTCTATTGTCTAGCTAAGGGCTTTCGGTCCACCAGT
AAATAAGATCAAATGCTCTTAAATGTTCCTGTTACCATCCTAATGTAAATACTGGATTTTTCTGTCATTTAGCACCATGCTGCTTCTGTC
TGTCTTAATGCTGGCATTAAGATCATGAGCCCTTTTTCTCCAGTAGTACAGGCTTTGAAAACTACTTCTATTAAGTTATTGATGCAATTT
GATATTTTTTCATAATCTATATTTAAACAAAATTACATCATTGCATCATCTTTTCTAAATTCATCTCCATTAAAACTTGCCTTAAGCTAC

>101085_101085_8_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000564323_CBFB_chr16_67116116_ENST00000412916_length(amino acids)=133AA_BP=78
MPHRCGHCPTPVRLRPLWAAPPQIRIGDNRGFGGGGRSCPRLWVGRRSRNPEPPRGAPAPEPGPGEAGMAPRPPTAAPQQEDALAQQAFE

--------------------------------------------------------------
>101085_101085_9_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000564323_CBFB_chr16_67116116_ENST00000561924_length(transcript)=476nt_BP=247nt
ACTTCCAGTTCTGCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCAGAATTGG
AGATAACCGAGGCTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCAGAGGCGC
TCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACA
GGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGCT
GCTGGCAGTAACTGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATAG

>101085_101085_9_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000564323_CBFB_chr16_67116116_ENST00000561924_length(amino acids)=128AA_BP=78
MPHRCGHCPTPVRLRPLWAAPPQIRIGDNRGFGGGGRSCPRLWVGRRSRNPEPPRGAPAPEPGPGEAGMAPRPPTAAPQQEDALAQQAFE

--------------------------------------------------------------
>101085_101085_10_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000570495_CBFB_chr16_67116116_ENST00000290858_length(transcript)=2801nt_BP=325nt
CGGGCCTCTGGGAAGTGTAGTTCGCGCGCCCGGCGTGGACCCGGGGTTGCAGGAGCGAGGCTCCGAGTGCGCAGGCGCACTTCCAGTTCT
GCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCAGAATTGGAGATAACCGAGG
CTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCAGAGGCGCTCCTGCCCCGGA
GCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGA
GGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGCTGCTGGCAGTAAC
TGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATAGCACAGCAGATGT
GTGCTGCCCATCTTTACATACACATTGCTTCTAGTTGGCAGAAATAATTGATTAAAAGACCAGAAACTGTGATAACTGGAGGTACTACGG
TCTATTTCTCAACCTTAGGCAGTAATAGACATCACAAACTGCCATGGTTTTGCACTATGATTATAATACCTGCATTTCTAATTTTTTAAG
CATGTAGCCAGTAATAATTTGAAGTTTTTTTTCTATGCAAGCTTACCTTGTTGGCATTATTTTAGGGAGTTGAAACTATCAACTGTAAAG
CTCCTTTTCTTCCACTTTAATTTAAAAGTTCATGTCATTTAAAAACAAGTCAAGAAATTAAAATTGTATCAGAGGGTTTTCTCTAATCAT
TTTTTCTATTTTTTTTTTTGTACTTCTAGATGTTTTGGTTATACAGCTTCATTTTAGATGAGCATTCTTATTTTTTGTTTTGTTTGCCCC
ATTTCCTTTTGTGTTTTTATAGTCTATAGCATTTTAAAACTGCTGATGTTGTTTGCATTATTTACAGGCTAAAAACTTAGTAGCATAGAG
CTGTCTGCCACAGCCTTCTGACAAAGTTTACAGTTATTAAAGTTGCAGTATCCTTTTAAATGCTAGTAATCAGCACTCTTTCTTTTTTTT
TTTTTTAATAGAGACAGGGTCTCGCAGTGTTGCCCAGGCTGGTCTCGAACTCCTGGCATCAAGCGATCCTCCTGCCTTAGCCTCCCAGAG
TACTGGGATTACAGGCTCTTTCTTTTTAAACATAAAAGTTTTAAATTGGTATTAACTCTGTACTCTGCCCTAGATTGTTTTAGCTTCTGT
TCTGTAATCATGAGTTTGGTTGGAGATATTCTCCATAGATGATCTTCTACTGAAATGCCTAAAGAAGTCACAGGCTGGCTTCTGTTTTAT
TCAGGGATTTTTTTAAAAAGTCAATCAGAAAAGGGATACTGGAGCTTCTTCATGTATGTAACAGCATATTAAACTGGAGACAGTGATGAA
TCAGCTACAAAGGTAATATTGTATTAAAATCATGTTTAAGATAGCTGCTTTTATGTGTATTTTATATTGCATGCTTTTGTAAAAACATGC
TGGGTGATGAAAGATTAGTTTTAGAGAGAAAATGTTCATCTGTGCAGAGGATGCATTTTCTTCCATTAATTCTGGAAAAAACGTTCACAG
TTATATATATGGTATTTTGCAAAAGGACTATTAATAGAACCTTTTGAGATGAATTAATGTAAGAATATTTTTTAAATAGGCTTACTGTCA
AATTGCAACTTTTTTTTTAGATACAGAGTGGAAAACAGTGCTAAGTCATTTGGCACCTCCTTACAAATATTTTTCATGGTCACATTTATT
AAATGTTACTACATTTCTGAATTTTTGAAAAATGTATTTTATCATTAAATGGCATTATTTTAAAGGGTGAAAAACTGACACAGTCAATTC
AGAAAATGGACTGAAGTCTGAATAAGGTCATTGCATTTAAAAAGCATATAACTGTACTTGACTGATGAGGGAGGTGTTACTTTCATTGTA
TATAGGTCTTATTTCATAAACAGATATCCTGTATCAAATAAAAGTATTTGTTATATATTTGAAGTTATGCATGGAAAGGAGTGTGTTTAA
ATTGTTACAAACAATAATGCGTCATTAAAGGCCATGCTGATCTTGCATAACTATAAGTACTATGAATGAATTTGGTTGGTTTTGGTGTTG
TACAGCTCACATGTTTACACACTCAGTGCCCTAATTTCCCCTGAGGGAATCGCTTTTTAAGTGATCCTTACAGTGGTGTTTTATGTTACT
TTATTACAGAGCTCCTTGGTTTTTTACTTCTGCACTTAAATTTTTTTAAATAACATGATGATGGTACATTTTCCTCTATTGTCTAGCTAA
GGGCTTTCGGTCCACCAGTAAATAAGATCAAATGCTCTTAAATGTTCCTGTTACCATCCTAATGTAAATACTGGATTTTTCTGTCATTTA
GCACCATGCTGCTTCTGTCTGTCTTAATGCTGGCATTAAGATCATGAGCCCTTTTTCTCCAGTAGTACAGGCTTTGAAAACTACTTCTAT
TAAGTTATTGATGCAATTTGATATTTTTTCATAATCTATATTTAAACAAAATTACATCATTGCATCATCTTTTCTAAATTCATCTCCATT
AAAACTTGCCTTAAGCTACCAGATTGCTTTTGCCACCATTGGCCATACTGTGTGTTTGTTTGTTTAATTTACTTTCACAATAAACTTCTG

>101085_101085_10_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000570495_CBFB_chr16_67116116_ENST00000290858_length(amino acids)=155AA_BP=105
MGSVVRAPGVDPGLQERGSECAGALPVLPHRCGHCPTPVRLRPLWAAPPQIRIGDNRGFGGGGRSCPRLWVGRRSRNPEPPRGAPAPEPG

--------------------------------------------------------------
>101085_101085_11_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000570495_CBFB_chr16_67116116_ENST00000412916_length(transcript)=2734nt_BP=325nt
CGGGCCTCTGGGAAGTGTAGTTCGCGCGCCCGGCGTGGACCCGGGGTTGCAGGAGCGAGGCTCCGAGTGCGCAGGCGCACTTCCAGTTCT
GCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCAGAATTGGAGATAACCGAGG
CTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCAGAGGCGCTCCTGCCCCGGA
GCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGA
GGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGCAAGAAGACAACAAGACCCTAGTCCTGG
TTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATAGCACAGCAGATGTGTGCTGCCCATCTTTACATACACATTGCTTC
TAGTTGGCAGAAATAATTGATTAAAAGACCAGAAACTGTGATAACTGGAGGTACTACGGTCTATTTCTCAACCTTAGGCAGTAATAGACA
TCACAAACTGCCATGGTTTTGCACTATGATTATAATACCTGCATTTCTAATTTTTTAAGCATGTAGCCAGTAATAATTTGAAGTTTTTTT
TCTATGCAAGCTTACCTTGTTGGCATTATTTTAGGGAGTTGAAACTATCAACTGTAAAGCTCCTTTTCTTCCACTTTAATTTAAAAGTTC
ATGTCATTTAAAAACAAGTCAAGAAATTAAAATTGTATCAGAGGGTTTTCTCTAATCATTTTTTCTATTTTTTTTTTTGTACTTCTAGAT
GTTTTGGTTATACAGCTTCATTTTAGATGAGCATTCTTATTTTTTGTTTTGTTTGCCCCATTTCCTTTTGTGTTTTTATAGTCTATAGCA
TTTTAAAACTGCTGATGTTGTTTGCATTATTTACAGGCTAAAAACTTAGTAGCATAGAGCTGTCTGCCACAGCCTTCTGACAAAGTTTAC
AGTTATTAAAGTTGCAGTATCCTTTTAAATGCTAGTAATCAGCACTCTTTCTTTTTTTTTTTTTTAATAGAGACAGGGTCTCGCAGTGTT
GCCCAGGCTGGTCTCGAACTCCTGGCATCAAGCGATCCTCCTGCCTTAGCCTCCCAGAGTACTGGGATTACAGGCTCTTTCTTTTTAAAC
ATAAAAGTTTTAAATTGGTATTAACTCTGTACTCTGCCCTAGATTGTTTTAGCTTCTGTTCTGTAATCATGAGTTTGGTTGGAGATATTC
TCCATAGATGATCTTCTACTGAAATGCCTAAAGAAGTCACAGGCTGGCTTCTGTTTTATTCAGGGATTTTTTTAAAAAGTCAATCAGAAA
AGGGATACTGGAGCTTCTTCATGTATGTAACAGCATATTAAACTGGAGACAGTGATGAATCAGCTACAAAGGTAATATTGTATTAAAATC
ATGTTTAAGATAGCTGCTTTTATGTGTATTTTATATTGCATGCTTTTGTAAAAACATGCTGGGTGATGAAAGATTAGTTTTAGAGAGAAA
ATGTTCATCTGTGCAGAGGATGCATTTTCTTCCATTAATTCTGGAAAAAACGTTCACAGTTATATATATGGTATTTTGCAAAAGGACTAT
TAATAGAACCTTTTGAGATGAATTAATGTAAGAATATTTTTTAAATAGGCTTACTGTCAAATTGCAACTTTTTTTTTAGATACAGAGTGG
AAAACAGTGCTAAGTCATTTGGCACCTCCTTACAAATATTTTTCATGGTCACATTTATTAAATGTTACTACATTTCTGAATTTTTGAAAA
ATGTATTTTATCATTAAATGGCATTATTTTAAAGGGTGAAAAACTGACACAGTCAATTCAGAAAATGGACTGAAGTCTGAATAAGGTCAT
TGCATTTAAAAAGCATATAACTGTACTTGACTGATGAGGGAGGTGTTACTTTCATTGTATATAGGTCTTATTTCATAAACAGATATCCTG
TATCAAATAAAAGTATTTGTTATATATTTGAAGTTATGCATGGAAAGGAGTGTGTTTAAATTGTTACAAACAATAATGCGTCATTAAAGG
CCATGCTGATCTTGCATAACTATAAGTACTATGAATGAATTTGGTTGGTTTTGGTGTTGTACAGCTCACATGTTTACACACTCAGTGCCC
TAATTTCCCCTGAGGGAATCGCTTTTTAAGTGATCCTTACAGTGGTGTTTTATGTTACTTTATTACAGAGCTCCTTGGTTTTTTACTTCT
GCACTTAAATTTTTTTAAATAACATGATGATGGTACATTTTCCTCTATTGTCTAGCTAAGGGCTTTCGGTCCACCAGTAAATAAGATCAA
ATGCTCTTAAATGTTCCTGTTACCATCCTAATGTAAATACTGGATTTTTCTGTCATTTAGCACCATGCTGCTTCTGTCTGTCTTAATGCT
GGCATTAAGATCATGAGCCCTTTTTCTCCAGTAGTACAGGCTTTGAAAACTACTTCTATTAAGTTATTGATGCAATTTGATATTTTTTCA
TAATCTATATTTAAACAAAATTACATCATTGCATCATCTTTTCTAAATTCATCTCCATTAAAACTTGCCTTAAGCTACCAGATTGCTTTT

>101085_101085_11_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000570495_CBFB_chr16_67116116_ENST00000412916_length(amino acids)=160AA_BP=105
MGSVVRAPGVDPGLQERGSECAGALPVLPHRCGHCPTPVRLRPLWAAPPQIRIGDNRGFGGGGRSCPRLWVGRRSRNPEPPRGAPAPEPG

--------------------------------------------------------------
>101085_101085_12_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000570495_CBFB_chr16_67116116_ENST00000561924_length(transcript)=554nt_BP=325nt
CGGGCCTCTGGGAAGTGTAGTTCGCGCGCCCGGCGTGGACCCGGGGTTGCAGGAGCGAGGCTCCGAGTGCGCAGGCGCACTTCCAGTTCT
GCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCAGAATTGGAGATAACCGAGG
CTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCAGAGGCGCTCCTGCCCCGGA
GCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGA
GGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGCTGCTGGCAGTAAC
TGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATAGCACAGCAGATGT

>101085_101085_12_ZFP90-CBFB_ZFP90_chr16_68573728_ENST00000570495_CBFB_chr16_67116116_ENST00000561924_length(amino acids)=155AA_BP=105
MGSVVRAPGVDPGLQERGSECAGALPVLPHRCGHCPTPVRLRPLWAAPPQIRIGDNRGFGGGGRSCPRLWVGRRSRNPEPPRGAPAPEPG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZFP90-CBFB


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZFP90-CBFB


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZFP90-CBFB


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0023467Leukemia, Myelocytic, Acute2CTD_human
TgeneC0023479Acute myelomonocytic leukemia2CTD_human;ORPHANET
TgeneC0026998Acute Myeloid Leukemia, M12CTD_human
TgeneC1879321Acute Myeloid Leukemia (AML-M2)2CTD_human
TgeneC0005941Bone Diseases, Developmental1CTD_human
TgeneC0008925Cleft Palate1CTD_human
TgeneC0018798Congenital Heart Defects1CTD_human
TgeneC0029396Heterotopic Ossification1CTD_human
TgeneC1837218Cleft palate, isolated1CTD_human