Fusion Gene Studies
in Kim Lab

FusionBase FusionGDB FusionGDB2 FusionPDB FusionNeoAntigen FusionAI FusionNW FGviewer Publication Contact
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:B3GALNT2-LYST (FusionGDB2 ID:HG148789TG1130)

Fusion Gene Summary for B3GALNT2-LYST

check button Fusion gene summary
Fusion gene informationFusion gene name: B3GALNT2-LYST
Fusion gene ID: hg148789tg1130
HgeneTgene
Gene symbol

B3GALNT2

LYST

Gene ID

148789

1130

Gene namebeta-1,3-N-acetylgalactosaminyltransferase 2lysosomal trafficking regulator
SynonymsB3GalNAc-T2|MDDGA11CHS|CHS1
Cytomap('B3GALNT2')('LYST')

1q42.3

1q42.3

Type of geneprotein-codingprotein-coding
DescriptionUDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2UDP-GalNAc:betaGlcNAc beta-1,3-galactosaminyltransferase, polypeptide 2beta-1,3-GalNAc-T2lysosomal-trafficking regulatorChediak-Higashi syndrome 1beige homolog
Modification date2020031320200313
UniProtAcc

Q8NCR0

.
Ensembl transtripts involved in fusion geneENST00000313984, ENST00000366600, 
ENST00000494378, 
Fusion gene scores* DoF score7 X 8 X 7=3928 X 8 X 5=320
# samples 88
** MAII scorelog2(8/392*10)=-2.29278174922785
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/320*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: B3GALNT2 [Title/Abstract] AND LYST [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointB3GALNT2(235647638)-LYST(235850347), # samples:1
Anticipated loss of major functional domain due to fusion event.B3GALNT2-LYST seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
B3GALNT2-LYST seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneB3GALNT2

GO:0006493

protein O-linked glycosylation

23929950


check buttonFusion gene breakpoints across B3GALNT2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across LYST (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-G2-AA3B-01AB3GALNT2chr1

235647638

-LYSTchr1

235850347

-


Top

Fusion Gene ORF analysis for B3GALNT2-LYST

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000313984ENST00000473037B3GALNT2chr1

235647638

-LYSTchr1

235850347

-
5CDS-5UTRENST00000366600ENST00000473037B3GALNT2chr1

235647638

-LYSTchr1

235850347

-
5CDS-intronENST00000313984ENST00000536965B3GALNT2chr1

235647638

-LYSTchr1

235850347

-
5CDS-intronENST00000366600ENST00000536965B3GALNT2chr1

235647638

-LYSTchr1

235850347

-
5UTR-3CDSENST00000494378ENST00000389793B3GALNT2chr1

235647638

-LYSTchr1

235850347

-
5UTR-3CDSENST00000494378ENST00000389794B3GALNT2chr1

235647638

-LYSTchr1

235850347

-
5UTR-5UTRENST00000494378ENST00000473037B3GALNT2chr1

235647638

-LYSTchr1

235850347

-
5UTR-intronENST00000494378ENST00000536965B3GALNT2chr1

235647638

-LYSTchr1

235850347

-
In-frameENST00000313984ENST00000389793B3GALNT2chr1

235647638

-LYSTchr1

235850347

-
In-frameENST00000313984ENST00000389794B3GALNT2chr1

235647638

-LYSTchr1

235850347

-
In-frameENST00000366600ENST00000389793B3GALNT2chr1

235647638

-LYSTchr1

235850347

-
In-frameENST00000366600ENST00000389794B3GALNT2chr1

235647638

-LYSTchr1

235850347

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000366600B3GALNT2chr1235647638-ENST00000389794LYSTchr1235850347-3388784491488479
ENST00000366600B3GALNT2chr1235647638-ENST00000389793LYSTchr1235850347-3379784491488479
ENST00000313984B3GALNT2chr1235647638-ENST00000389794LYSTchr1235850347-34528481701552460
ENST00000313984B3GALNT2chr1235647638-ENST00000389793LYSTchr1235850347-34438481701552460

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000366600ENST00000389794B3GALNT2chr1235647638-LYSTchr1235850347-0.0003883980.9996117
ENST00000366600ENST00000389793B3GALNT2chr1235647638-LYSTchr1235850347-0.0003927930.99960726
ENST00000313984ENST00000389794B3GALNT2chr1235647638-LYSTchr1235850347-0.0007709220.9992291
ENST00000313984ENST00000389793B3GALNT2chr1235647638-LYSTchr1235850347-0.0007789560.9992211

Top

Fusion Genomic Features for B3GALNT2-LYST


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

Top

Fusion Protein Features for B3GALNT2-LYST


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:235647638/chr1:235850347)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
B3GALNT2

Q8NCR0

.
FUNCTION: Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N- and O-glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan (DAG1) glycosylation: acts coordinately with GTDC2/POMGnT2 to synthesize a GalNAc-beta3-GlcNAc-beta-terminus at the 4-position of protein O-mannose in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan, which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. {ECO:0000269|PubMed:14724282, ECO:0000269|PubMed:23453667, ECO:0000269|PubMed:23929950}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneB3GALNT2chr1:235647638chr1:235850347ENST00000313984-581_6226327.0Topological domainCytoplasmic
HgeneB3GALNT2chr1:235647638chr1:235850347ENST00000366600-4121_6185501.0Topological domainCytoplasmic
HgeneB3GALNT2chr1:235647638chr1:235850347ENST00000313984-587_23226327.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneB3GALNT2chr1:235647638chr1:235850347ENST00000366600-4127_23185501.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979346533614_365335673802.0RepeatNote=WD 4
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979346533656_369935673802.0RepeatNote=WD 5
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979346533700_374435673802.0RepeatNote=WD 6
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979346533749_378835673802.0RepeatNote=WD 7
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979446533614_365335673802.0RepeatNote=WD 4
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979446533656_369935673802.0RepeatNote=WD 5
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979446533700_374435673802.0RepeatNote=WD 6
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979446533749_378835673802.0RepeatNote=WD 7

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneB3GALNT2chr1:235647638chr1:235850347ENST00000313984-5824_500226327.0Topological domainLumenal
HgeneB3GALNT2chr1:235647638chr1:235850347ENST00000366600-41224_500185501.0Topological domainLumenal
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979346532448_245235673802.0Compositional biasNote=Poly-Leu
TgeneLYSTchr1:235647638chr1:235850347ENST00000389793465331_3635673802.0Compositional biasNote=Poly-Glu
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979446532448_245235673802.0Compositional biasNote=Poly-Leu
TgeneLYSTchr1:235647638chr1:235850347ENST00000389794465331_3635673802.0Compositional biasNote=Poly-Glu
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979346533009_311535673802.0DomainBEACH-type PH
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979346533120_342235673802.0DomainBEACH
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979446533009_311535673802.0DomainBEACH-type PH
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979446533120_342235673802.0DomainBEACH
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979346531582_162635673802.0RepeatNote=WD 2
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979346533563_360235673802.0RepeatNote=WD 3
TgeneLYSTchr1:235647638chr1:235850347ENST000003897934653662_70035673802.0RepeatNote=WD 1
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979446531582_162635673802.0RepeatNote=WD 2
TgeneLYSTchr1:235647638chr1:235850347ENST0000038979446533563_360235673802.0RepeatNote=WD 3
TgeneLYSTchr1:235647638chr1:235850347ENST000003897944653662_70035673802.0RepeatNote=WD 1


Top

Fusion Gene Sequence for B3GALNT2-LYST


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>8661_8661_1_B3GALNT2-LYST_B3GALNT2_chr1_235647638_ENST00000313984_LYST_chr1_235850347_ENST00000389793_length(transcript)=3443nt_BP=848nt
GGAGGAGCGGGGCCGGGAGCTGCGAGGAGCCCTCCAGACGTCGCCGAGCGCGAGGGCGGGCGTGCTCGGAGTGGTCGCTCGTCAGCCGCC
GCCCCTCAGTCTCCGCACTTGCAGGTCCCCTCCCTCTCCGCCGGGACGCGGGAGAGCCCGGCTCGCGGCGGGGGCGGCCAATGCGAAACT
GGCTGGTGCTGCTGTGCCCGTGTGTGCTCGGGGCCGCGCTGCACCTCTGGCTGCGGCTGCGCTCCCCGCCGCCCGCCTGCGCCTCCGGGG
CCGGCCCTGCAGGTGGAGTCTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGCGCGGTCTCGGCTCACCCCAACCTCCACCTCCCGGGTT
CAAGAGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATAACAGATCAGTTGGCCTTATTTCCTCAGTGGAAATCTACTCACTATGATG
TGGTAGTTGGCGTGTTGTCAGCTCGCAATAACCATGAACTTCGAAACGTGATAAGAAGCACCTGGATGAGACATTTGCTACAGCATCCCA
CATTAAGTCAACGTGTGCTTGTGAAGTTCATAATAGGTGCTCATGGCTGTGAAGTGCCTGTGGAAGACAGGGAAGATCCTTATTCCTGTA
AACTACTCAACATCACAAATCCAGTTTTGAATCAGGAAATTGAAGCGTTCAGTCTGTCCGAAGACACTTCATCGGGGCTGCCTGAGGATC
GAGTTGTCAGCGTGAGTTTCCGAGTTCTCTACCCCATCGTTATTACCAGTCTTGGAGTGTTCTACGATGCCAATGATGTGGGTTTCCAGA
GGAACATCACTGTCAAACTTTATCAGGCAGAACAAGAGGTGACTAGTTGTGCTTGGGTGCCTGACAGTTGCCAGCTGTTTACTGGAAGCA
AATGCGGTGTCATCACAGCCTACACAAACAGATTTACAAGCAGCACGCCATCAGAAATAGAAATGGAGACTCAAATACATCTCTATGGTC
ACACAGAAGAGATAACCAGCTTATTTGTTTGCAAACCATACAGTATACTGATAAGTGTGAGCAGAGACGGAACCTGCATCATATGGGATT
TAAACAGGTTATGCTATGTACAAAGTCTGGCGGGACACAAAAGCCCTGTCACAGCTGTCTCTGCCAGTGAAACCTCAGGTGATATTGCTA
CTGTGTGTGATTCAGCTGGCGGAGGCAGTGACCTCAGACTCTGGACGGTGAACGGGGATCTCGTTGGACATGTCCACTGCAGGGAGATCA
TCTGTTCCGTGGCTTTCTCCAACCAGCCTGAGGGAGTATCTATCAATGTAATCGCTGGGGGATTAGAAAATGGAATTGTAAGGTTATGGA
GCACATGGGACTTAAAGCCTGTGAGAGAAATTACATTTCCCAAATCAAATAAGCCCATCATCAGCCTTACATTTTCTTGTGATGGCCACC
ATTTGTACACAGCAAACAGTGATGGGACCGTGATTGCCTGGTGTCGGAAGGACCAGCAGCGCTTGAAACAGCCAATGTTCTATTCCTTCC
TTAGCAGCTATGCAGCCGGGTGAATGCGAATGAACTTCACGTTCTCCAAAGCACTTTAACTCCAAACTAGATTTGTTGACTTCACCAGTT
TTAGGAGGTTGAACCTAAAGAAATGGATGACTGGACAAACCATCCAAATAATGATAAAGTCTATTCATCTGCACAAAATTCTGAAGAGTC
ACATGATCCTAAGAGGAAAGTTCTGTTCTATTTTAGTGATAATCTGGAAGATTGTGTCAATATGCACTAGCCAACAAGTTTTAAGCCTCG
CATGGTACATTAAAATGATATTCTTAAAATTTTTTCCCACCAAGGTATTCCAAAGAAAATATTAAGGTCTCCCCTTTTTCTATGATTCCA
AAAGGACCAGTAGAATTTAAATTGGTTGGTTGATTGTTTATATAAAACACACTAAAATTATATTTTAAAAGTTTACTGCCATGAAATACT
CCTCCCACCACACACACATGCTCCAAAAGAGGAAAGAAAAAAAGATAATTTTTAGGACTTGATAATTGCTTTCTTTGAGAAGCAAATTAT
TCAGTAGGTGCCTCTGTACCAAATATTTTATGGAATATCTAAATACTAAAATAAACTATGAATGAATCTCAAAATTAGGCAGTTTTTGCC
AGTTGCTTTCTTAGCTCAAAGGAGAACCAGAATTTTTTTGACAGCCACAAACAAGAATACAGGTATCTTGGATTTCAGACACATTCTGTT
TCTTCATAAAAATTTTACTTAAAATCTGTAACGCTAGATATTGACTATCCTTAGTTGAGTCACTGAGGTTTAAACACAATGGTAAGTCTT
AAAGTCTGCTATTTACAGAGCATTGAATCTGTACCAATTTGCAATAGAAAGCCTTCAGTATGCAAGAAGTTTGCATGGGTATTAAGAACA
CAGCCTAAATAAGGCATTTGATCTAATCTGCAGGAAGAATTTTCTTCCCCAAAACAGAATTATAAAAGCTTACTTTAAACAGGAGGCAGA
ATAATTCTTTTAGGAAACCATTTCATTCTGTTTCTACTAACCTATACCATCTGAGAATTCTAGGAAGAATAATAAAATCTCGTGTATTCC
ACAGCAAACTTACATACCATAAAGACAGAATTCCTAAACATCTTGGAGCCGTCTGTCTCTCCCATATGATGGCTGTCTGTATATTTTTAC
TTGGGGTGCTGCTTTATTGGCTTTGAAAACACTGTCAGATAAGCTCAGTAATATGTTACCATGGGATAAAAATATGTATCCCTGCCTAAG
AATAACTTGTGCATTTGTTATGGAAATTTAATTCATATGGTGTTTACAGTACTACTTTTGTAACTTCCAGACTTTCTAAAACATTCTGCT
TAAAAACCATATAAAATATAATTCCAAAGTCTCTGCTGTCAAGATAGATTCGAGAGAAAGCACGTGGCCATGTATGCTTTAACCTTAAAC
TGCATACACATGTAGTGATACCTAGGCTGCATTTAGATCACCGTGTGCTCAGGCCAGGTGTGAATCCTGAGGTCCATGGAGGTGCAGAGA
TGAGATTACTCCTATTCACGTTGAAGTGATTTGCTTTGTTAACAAAAAATTGCAGCTATTGTCTAGCTTTCATTTTTTTACTGAGAACTT
TAAATTAGTCCCCTATTAGAATAGGGTTGCTACTCATCTTTTTTTAAAAACCGAATTTCATCATTTATCTAAAGAGAAAATATGCAGAAT
AACTGGTCTTGTTAAGAGTGCAATATTATATTTTTATGTAAAAATAAAAATTAATTTGGGGGGATTATTTATTCAGCATGAAACCTAATA
TGTATATGTTTGAAATACTTCATAATGTGCATGTTGTAGCAAACATTTCTGTAAATTATCACAAGCTCTGTTACCTTTATATACACTGCC

>8661_8661_1_B3GALNT2-LYST_B3GALNT2_chr1_235647638_ENST00000313984_LYST_chr1_235850347_ENST00000389793_length(amino acids)=460AA_BP=40
MRNWLVLLCPCVLGAALHLWLRLRSPPPACASGAGPAGGVSLLLPRLECNGAVSAHPNLHLPGSRDSPASASQVAGITDQLALFPQWKST
HYDVVVGVLSARNNHELRNVIRSTWMRHLLQHPTLSQRVLVKFIIGAHGCEVPVEDREDPYSCKLLNITNPVLNQEIEAFSLSEDTSSGL
PEDRVVSVSFRVLYPIVITSLGVFYDANDVGFQRNITVKLYQAEQEVTSCAWVPDSCQLFTGSKCGVITAYTNRFTSSTPSEIEMETQIH
LYGHTEEITSLFVCKPYSILISVSRDGTCIIWDLNRLCYVQSLAGHKSPVTAVSASETSGDIATVCDSAGGGSDLRLWTVNGDLVGHVHC
REIICSVAFSNQPEGVSINVIAGGLENGIVRLWSTWDLKPVREITFPKSNKPIISLTFSCDGHHLYTANSDGTVIAWCRKDQQRLKQPMF

--------------------------------------------------------------
>8661_8661_2_B3GALNT2-LYST_B3GALNT2_chr1_235647638_ENST00000313984_LYST_chr1_235850347_ENST00000389794_length(transcript)=3452nt_BP=848nt
GGAGGAGCGGGGCCGGGAGCTGCGAGGAGCCCTCCAGACGTCGCCGAGCGCGAGGGCGGGCGTGCTCGGAGTGGTCGCTCGTCAGCCGCC
GCCCCTCAGTCTCCGCACTTGCAGGTCCCCTCCCTCTCCGCCGGGACGCGGGAGAGCCCGGCTCGCGGCGGGGGCGGCCAATGCGAAACT
GGCTGGTGCTGCTGTGCCCGTGTGTGCTCGGGGCCGCGCTGCACCTCTGGCTGCGGCTGCGCTCCCCGCCGCCCGCCTGCGCCTCCGGGG
CCGGCCCTGCAGGTGGAGTCTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGCGCGGTCTCGGCTCACCCCAACCTCCACCTCCCGGGTT
CAAGAGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATAACAGATCAGTTGGCCTTATTTCCTCAGTGGAAATCTACTCACTATGATG
TGGTAGTTGGCGTGTTGTCAGCTCGCAATAACCATGAACTTCGAAACGTGATAAGAAGCACCTGGATGAGACATTTGCTACAGCATCCCA
CATTAAGTCAACGTGTGCTTGTGAAGTTCATAATAGGTGCTCATGGCTGTGAAGTGCCTGTGGAAGACAGGGAAGATCCTTATTCCTGTA
AACTACTCAACATCACAAATCCAGTTTTGAATCAGGAAATTGAAGCGTTCAGTCTGTCCGAAGACACTTCATCGGGGCTGCCTGAGGATC
GAGTTGTCAGCGTGAGTTTCCGAGTTCTCTACCCCATCGTTATTACCAGTCTTGGAGTGTTCTACGATGCCAATGATGTGGGTTTCCAGA
GGAACATCACTGTCAAACTTTATCAGGCAGAACAAGAGGTGACTAGTTGTGCTTGGGTGCCTGACAGTTGCCAGCTGTTTACTGGAAGCA
AATGCGGTGTCATCACAGCCTACACAAACAGATTTACAAGCAGCACGCCATCAGAAATAGAAATGGAGACTCAAATACATCTCTATGGTC
ACACAGAAGAGATAACCAGCTTATTTGTTTGCAAACCATACAGTATACTGATAAGTGTGAGCAGAGACGGAACCTGCATCATATGGGATT
TAAACAGGTTATGCTATGTACAAAGTCTGGCGGGACACAAAAGCCCTGTCACAGCTGTCTCTGCCAGTGAAACCTCAGGTGATATTGCTA
CTGTGTGTGATTCAGCTGGCGGAGGCAGTGACCTCAGACTCTGGACGGTGAACGGGGATCTCGTTGGACATGTCCACTGCAGGGAGATCA
TCTGTTCCGTGGCTTTCTCCAACCAGCCTGAGGGAGTATCTATCAATGTAATCGCTGGGGGATTAGAAAATGGAATTGTAAGGTTATGGA
GCACATGGGACTTAAAGCCTGTGAGAGAAATTACATTTCCCAAATCAAATAAGCCCATCATCAGCCTTACATTTTCTTGTGATGGCCACC
ATTTGTACACAGCAAACAGTGATGGGACCGTGATTGCCTGGTGTCGGAAGGACCAGCAGCGCTTGAAACAGCCAATGTTCTATTCCTTCC
TTAGCAGCTATGCAGCCGGGTGAATGCGAATGAACTTCACGTTCTCCAAAGCACTTTAACTCCAAACTAGATTTGTTGACTTCACCAGTT
TTAGGAGGTTGAACCTAAAGAAATGGATGACTGGACAAACCATCCAAATAATGATAAAGTCTATTCATCTGCACAAAATTCTGAAGAGTC
ACATGATCCTAAGAGGAAAGTTCTGTTCTATTTTAGTGATAATCTGGAAGATTGTGTCAATATGCACTAGCCAACAAGTTTTAAGCCTCG
CATGGTACATTAAAATGATATTCTTAAAATTTTTTCCCACCAAGGTATTCCAAAGAAAATATTAAGGTCTCCCCTTTTTCTATGATTCCA
AAAGGACCAGTAGAATTTAAATTGGTTGGTTGATTGTTTATATAAAACACACTAAAATTATATTTTAAAAGTTTACTGCCATGAAATACT
CCTCCCACCACACACACATGCTCCAAAAGAGGAAAGAAAAAAAGATAATTTTTAGGACTTGATAATTGCTTTCTTTGAGAAGCAAATTAT
TCAGTAGGTGCCTCTGTACCAAATATTTTATGGAATATCTAAATACTAAAATAAACTATGAATGAATCTCAAAATTAGGCAGTTTTTGCC
AGTTGCTTTCTTAGCTCAAAGGAGAACCAGAATTTTTTTGACAGCCACAAACAAGAATACAGGTATCTTGGATTTCAGACACATTCTGTT
TCTTCATAAAAATTTTACTTAAAATCTGTAACGCTAGATATTGACTATCCTTAGTTGAGTCACTGAGGTTTAAACACAATGGTAAGTCTT
AAAGTCTGCTATTTACAGAGCATTGAATCTGTACCAATTTGCAATAGAAAGCCTTCAGTATGCAAGAAGTTTGCATGGGTATTAAGAACA
CAGCCTAAATAAGGCATTTGATCTAATCTGCAGGAAGAATTTTCTTCCCCAAAACAGAATTATAAAAGCTTACTTTAAACAGGAGGCAGA
ATAATTCTTTTAGGAAACCATTTCATTCTGTTTCTACTAACCTATACCATCTGAGAATTCTAGGAAGAATAATAAAATCTCGTGTATTCC
ACAGCAAACTTACATACCATAAAGACAGAATTCCTAAACATCTTGGAGCCGTCTGTCTCTCCCATATGATGGCTGTCTGTATATTTTTAC
TTGGGGTGCTGCTTTATTGGCTTTGAAAACACTGTCAGATAAGCTCAGTAATATGTTACCATGGGATAAAAATATGTATCCCTGCCTAAG
AATAACTTGTGCATTTGTTATGGAAATTTAATTCATATGGTGTTTACAGTACTACTTTTGTAACTTCCAGACTTTCTAAAACATTCTGCT
TAAAAACCATATAAAATATAATTCCAAAGTCTCTGCTGTCAAGATAGATTCGAGAGAAAGCACGTGGCCATGTATGCTTTAACCTTAAAC
TGCATACACATGTAGTGATACCTAGGCTGCATTTAGATCACCGTGTGCTCAGGCCAGGTGTGAATCCTGAGGTCCATGGAGGTGCAGAGA
TGAGATTACTCCTATTCACGTTGAAGTGATTTGCTTTGTTAACAAAAAATTGCAGCTATTGTCTAGCTTTCATTTTTTTACTGAGAACTT
TAAATTAGTCCCCTATTAGAATAGGGTTGCTACTCATCTTTTTTTAAAAACCGAATTTCATCATTTATCTAAAGAGAAAATATGCAGAAT
AACTGGTCTTGTTAAGAGTGCAATATTATATTTTTATGTAAAAATAAAAATTAATTTGGGGGGATTATTTATTCAGCATGAAACCTAATA
TGTATATGTTTGAAATACTTCATAATGTGCATGTTGTAGCAAACATTTCTGTAAATTATCACAAGCTCTGTTACCTTTATATACACTGCC

>8661_8661_2_B3GALNT2-LYST_B3GALNT2_chr1_235647638_ENST00000313984_LYST_chr1_235850347_ENST00000389794_length(amino acids)=460AA_BP=40
MRNWLVLLCPCVLGAALHLWLRLRSPPPACASGAGPAGGVSLLLPRLECNGAVSAHPNLHLPGSRDSPASASQVAGITDQLALFPQWKST
HYDVVVGVLSARNNHELRNVIRSTWMRHLLQHPTLSQRVLVKFIIGAHGCEVPVEDREDPYSCKLLNITNPVLNQEIEAFSLSEDTSSGL
PEDRVVSVSFRVLYPIVITSLGVFYDANDVGFQRNITVKLYQAEQEVTSCAWVPDSCQLFTGSKCGVITAYTNRFTSSTPSEIEMETQIH
LYGHTEEITSLFVCKPYSILISVSRDGTCIIWDLNRLCYVQSLAGHKSPVTAVSASETSGDIATVCDSAGGGSDLRLWTVNGDLVGHVHC
REIICSVAFSNQPEGVSINVIAGGLENGIVRLWSTWDLKPVREITFPKSNKPIISLTFSCDGHHLYTANSDGTVIAWCRKDQQRLKQPMF

--------------------------------------------------------------
>8661_8661_3_B3GALNT2-LYST_B3GALNT2_chr1_235647638_ENST00000366600_LYST_chr1_235850347_ENST00000389793_length(transcript)=3379nt_BP=784nt
AGGCGGAGGGGGCGGGGCTTCGGCCGGCTAAGCCGCGGCCACCCGCGGTCTGAGGGACCGGAGGAGCGGGGCCGGGAGCTGCGAGGAGCC
CTCCAGACGTCGCCGAGCGCGAGGGCGGGCGTGCTCGGAGTGGTCGCTCGTCAGCCGCCGCCCCTCAGTCTCCGCACTTGCAGGTCCCCT
CCCTCTCCGCCGGGACGCGGGAGAGCCCGGCTCGCGGCGGGGGCGGCCAATGCGAAACTGGCTGGTGCTGCTGTGCCCGTGTGTGCTCGG
GGCCGCGCTGCACCTCTGGCTGCGGCTGCGCTCCCCGCCGCCCGCCTGCGCCTCCGGGGCCGGCCCTGCAGATCAGTTGGCCTTATTTCC
TCAGTGGAAATCTACTCACTATGATGTGGTAGTTGGCGTGTTGTCAGCTCGCAATAACCATGAACTTCGAAACGTGATAAGAAGCACCTG
GATGAGACATTTGCTACAGCATCCCACATTAAGTCAACGTGTGCTTGTGAAGTTCATAATAGGTGCTCATGGCTGTGAAGTGCCTGTGGA
AGACAGGGAAGATCCTTATTCCTGTAAACTACTCAACATCACAAATCCAGTTTTGAATCAGGAAATTGAAGCGTTCAGTCTGTCCGAAGA
CACTTCATCGGGGCTGCCTGAGGATCGAGTTGTCAGCGTGAGTTTCCGAGTTCTCTACCCCATCGTTATTACCAGTCTTGGAGTGTTCTA
CGATGCCAATGATGTGGGTTTCCAGAGGAACATCACTGTCAAACTTTATCAGGCAGAACAAGAGGTGACTAGTTGTGCTTGGGTGCCTGA
CAGTTGCCAGCTGTTTACTGGAAGCAAATGCGGTGTCATCACAGCCTACACAAACAGATTTACAAGCAGCACGCCATCAGAAATAGAAAT
GGAGACTCAAATACATCTCTATGGTCACACAGAAGAGATAACCAGCTTATTTGTTTGCAAACCATACAGTATACTGATAAGTGTGAGCAG
AGACGGAACCTGCATCATATGGGATTTAAACAGGTTATGCTATGTACAAAGTCTGGCGGGACACAAAAGCCCTGTCACAGCTGTCTCTGC
CAGTGAAACCTCAGGTGATATTGCTACTGTGTGTGATTCAGCTGGCGGAGGCAGTGACCTCAGACTCTGGACGGTGAACGGGGATCTCGT
TGGACATGTCCACTGCAGGGAGATCATCTGTTCCGTGGCTTTCTCCAACCAGCCTGAGGGAGTATCTATCAATGTAATCGCTGGGGGATT
AGAAAATGGAATTGTAAGGTTATGGAGCACATGGGACTTAAAGCCTGTGAGAGAAATTACATTTCCCAAATCAAATAAGCCCATCATCAG
CCTTACATTTTCTTGTGATGGCCACCATTTGTACACAGCAAACAGTGATGGGACCGTGATTGCCTGGTGTCGGAAGGACCAGCAGCGCTT
GAAACAGCCAATGTTCTATTCCTTCCTTAGCAGCTATGCAGCCGGGTGAATGCGAATGAACTTCACGTTCTCCAAAGCACTTTAACTCCA
AACTAGATTTGTTGACTTCACCAGTTTTAGGAGGTTGAACCTAAAGAAATGGATGACTGGACAAACCATCCAAATAATGATAAAGTCTAT
TCATCTGCACAAAATTCTGAAGAGTCACATGATCCTAAGAGGAAAGTTCTGTTCTATTTTAGTGATAATCTGGAAGATTGTGTCAATATG
CACTAGCCAACAAGTTTTAAGCCTCGCATGGTACATTAAAATGATATTCTTAAAATTTTTTCCCACCAAGGTATTCCAAAGAAAATATTA
AGGTCTCCCCTTTTTCTATGATTCCAAAAGGACCAGTAGAATTTAAATTGGTTGGTTGATTGTTTATATAAAACACACTAAAATTATATT
TTAAAAGTTTACTGCCATGAAATACTCCTCCCACCACACACACATGCTCCAAAAGAGGAAAGAAAAAAAGATAATTTTTAGGACTTGATA
ATTGCTTTCTTTGAGAAGCAAATTATTCAGTAGGTGCCTCTGTACCAAATATTTTATGGAATATCTAAATACTAAAATAAACTATGAATG
AATCTCAAAATTAGGCAGTTTTTGCCAGTTGCTTTCTTAGCTCAAAGGAGAACCAGAATTTTTTTGACAGCCACAAACAAGAATACAGGT
ATCTTGGATTTCAGACACATTCTGTTTCTTCATAAAAATTTTACTTAAAATCTGTAACGCTAGATATTGACTATCCTTAGTTGAGTCACT
GAGGTTTAAACACAATGGTAAGTCTTAAAGTCTGCTATTTACAGAGCATTGAATCTGTACCAATTTGCAATAGAAAGCCTTCAGTATGCA
AGAAGTTTGCATGGGTATTAAGAACACAGCCTAAATAAGGCATTTGATCTAATCTGCAGGAAGAATTTTCTTCCCCAAAACAGAATTATA
AAAGCTTACTTTAAACAGGAGGCAGAATAATTCTTTTAGGAAACCATTTCATTCTGTTTCTACTAACCTATACCATCTGAGAATTCTAGG
AAGAATAATAAAATCTCGTGTATTCCACAGCAAACTTACATACCATAAAGACAGAATTCCTAAACATCTTGGAGCCGTCTGTCTCTCCCA
TATGATGGCTGTCTGTATATTTTTACTTGGGGTGCTGCTTTATTGGCTTTGAAAACACTGTCAGATAAGCTCAGTAATATGTTACCATGG
GATAAAAATATGTATCCCTGCCTAAGAATAACTTGTGCATTTGTTATGGAAATTTAATTCATATGGTGTTTACAGTACTACTTTTGTAAC
TTCCAGACTTTCTAAAACATTCTGCTTAAAAACCATATAAAATATAATTCCAAAGTCTCTGCTGTCAAGATAGATTCGAGAGAAAGCACG
TGGCCATGTATGCTTTAACCTTAAACTGCATACACATGTAGTGATACCTAGGCTGCATTTAGATCACCGTGTGCTCAGGCCAGGTGTGAA
TCCTGAGGTCCATGGAGGTGCAGAGATGAGATTACTCCTATTCACGTTGAAGTGATTTGCTTTGTTAACAAAAAATTGCAGCTATTGTCT
AGCTTTCATTTTTTTACTGAGAACTTTAAATTAGTCCCCTATTAGAATAGGGTTGCTACTCATCTTTTTTTAAAAACCGAATTTCATCAT
TTATCTAAAGAGAAAATATGCAGAATAACTGGTCTTGTTAAGAGTGCAATATTATATTTTTATGTAAAAATAAAAATTAATTTGGGGGGA
TTATTTATTCAGCATGAAACCTAATATGTATATGTTTGAAATACTTCATAATGTGCATGTTGTAGCAAACATTTCTGTAAATTATCACAA

>8661_8661_3_B3GALNT2-LYST_B3GALNT2_chr1_235647638_ENST00000366600_LYST_chr1_235850347_ENST00000389793_length(amino acids)=479AA_BP=245
MRDRRSGAGSCEEPSRRRRARGRACSEWSLVSRRPSVSALAGPLPLRRDAGEPGSRRGRPMRNWLVLLCPCVLGAALHLWLRLRSPPPAC
ASGAGPADQLALFPQWKSTHYDVVVGVLSARNNHELRNVIRSTWMRHLLQHPTLSQRVLVKFIIGAHGCEVPVEDREDPYSCKLLNITNP
VLNQEIEAFSLSEDTSSGLPEDRVVSVSFRVLYPIVITSLGVFYDANDVGFQRNITVKLYQAEQEVTSCAWVPDSCQLFTGSKCGVITAY
TNRFTSSTPSEIEMETQIHLYGHTEEITSLFVCKPYSILISVSRDGTCIIWDLNRLCYVQSLAGHKSPVTAVSASETSGDIATVCDSAGG
GSDLRLWTVNGDLVGHVHCREIICSVAFSNQPEGVSINVIAGGLENGIVRLWSTWDLKPVREITFPKSNKPIISLTFSCDGHHLYTANSD

--------------------------------------------------------------
>8661_8661_4_B3GALNT2-LYST_B3GALNT2_chr1_235647638_ENST00000366600_LYST_chr1_235850347_ENST00000389794_length(transcript)=3388nt_BP=784nt
AGGCGGAGGGGGCGGGGCTTCGGCCGGCTAAGCCGCGGCCACCCGCGGTCTGAGGGACCGGAGGAGCGGGGCCGGGAGCTGCGAGGAGCC
CTCCAGACGTCGCCGAGCGCGAGGGCGGGCGTGCTCGGAGTGGTCGCTCGTCAGCCGCCGCCCCTCAGTCTCCGCACTTGCAGGTCCCCT
CCCTCTCCGCCGGGACGCGGGAGAGCCCGGCTCGCGGCGGGGGCGGCCAATGCGAAACTGGCTGGTGCTGCTGTGCCCGTGTGTGCTCGG
GGCCGCGCTGCACCTCTGGCTGCGGCTGCGCTCCCCGCCGCCCGCCTGCGCCTCCGGGGCCGGCCCTGCAGATCAGTTGGCCTTATTTCC
TCAGTGGAAATCTACTCACTATGATGTGGTAGTTGGCGTGTTGTCAGCTCGCAATAACCATGAACTTCGAAACGTGATAAGAAGCACCTG
GATGAGACATTTGCTACAGCATCCCACATTAAGTCAACGTGTGCTTGTGAAGTTCATAATAGGTGCTCATGGCTGTGAAGTGCCTGTGGA
AGACAGGGAAGATCCTTATTCCTGTAAACTACTCAACATCACAAATCCAGTTTTGAATCAGGAAATTGAAGCGTTCAGTCTGTCCGAAGA
CACTTCATCGGGGCTGCCTGAGGATCGAGTTGTCAGCGTGAGTTTCCGAGTTCTCTACCCCATCGTTATTACCAGTCTTGGAGTGTTCTA
CGATGCCAATGATGTGGGTTTCCAGAGGAACATCACTGTCAAACTTTATCAGGCAGAACAAGAGGTGACTAGTTGTGCTTGGGTGCCTGA
CAGTTGCCAGCTGTTTACTGGAAGCAAATGCGGTGTCATCACAGCCTACACAAACAGATTTACAAGCAGCACGCCATCAGAAATAGAAAT
GGAGACTCAAATACATCTCTATGGTCACACAGAAGAGATAACCAGCTTATTTGTTTGCAAACCATACAGTATACTGATAAGTGTGAGCAG
AGACGGAACCTGCATCATATGGGATTTAAACAGGTTATGCTATGTACAAAGTCTGGCGGGACACAAAAGCCCTGTCACAGCTGTCTCTGC
CAGTGAAACCTCAGGTGATATTGCTACTGTGTGTGATTCAGCTGGCGGAGGCAGTGACCTCAGACTCTGGACGGTGAACGGGGATCTCGT
TGGACATGTCCACTGCAGGGAGATCATCTGTTCCGTGGCTTTCTCCAACCAGCCTGAGGGAGTATCTATCAATGTAATCGCTGGGGGATT
AGAAAATGGAATTGTAAGGTTATGGAGCACATGGGACTTAAAGCCTGTGAGAGAAATTACATTTCCCAAATCAAATAAGCCCATCATCAG
CCTTACATTTTCTTGTGATGGCCACCATTTGTACACAGCAAACAGTGATGGGACCGTGATTGCCTGGTGTCGGAAGGACCAGCAGCGCTT
GAAACAGCCAATGTTCTATTCCTTCCTTAGCAGCTATGCAGCCGGGTGAATGCGAATGAACTTCACGTTCTCCAAAGCACTTTAACTCCA
AACTAGATTTGTTGACTTCACCAGTTTTAGGAGGTTGAACCTAAAGAAATGGATGACTGGACAAACCATCCAAATAATGATAAAGTCTAT
TCATCTGCACAAAATTCTGAAGAGTCACATGATCCTAAGAGGAAAGTTCTGTTCTATTTTAGTGATAATCTGGAAGATTGTGTCAATATG
CACTAGCCAACAAGTTTTAAGCCTCGCATGGTACATTAAAATGATATTCTTAAAATTTTTTCCCACCAAGGTATTCCAAAGAAAATATTA
AGGTCTCCCCTTTTTCTATGATTCCAAAAGGACCAGTAGAATTTAAATTGGTTGGTTGATTGTTTATATAAAACACACTAAAATTATATT
TTAAAAGTTTACTGCCATGAAATACTCCTCCCACCACACACACATGCTCCAAAAGAGGAAAGAAAAAAAGATAATTTTTAGGACTTGATA
ATTGCTTTCTTTGAGAAGCAAATTATTCAGTAGGTGCCTCTGTACCAAATATTTTATGGAATATCTAAATACTAAAATAAACTATGAATG
AATCTCAAAATTAGGCAGTTTTTGCCAGTTGCTTTCTTAGCTCAAAGGAGAACCAGAATTTTTTTGACAGCCACAAACAAGAATACAGGT
ATCTTGGATTTCAGACACATTCTGTTTCTTCATAAAAATTTTACTTAAAATCTGTAACGCTAGATATTGACTATCCTTAGTTGAGTCACT
GAGGTTTAAACACAATGGTAAGTCTTAAAGTCTGCTATTTACAGAGCATTGAATCTGTACCAATTTGCAATAGAAAGCCTTCAGTATGCA
AGAAGTTTGCATGGGTATTAAGAACACAGCCTAAATAAGGCATTTGATCTAATCTGCAGGAAGAATTTTCTTCCCCAAAACAGAATTATA
AAAGCTTACTTTAAACAGGAGGCAGAATAATTCTTTTAGGAAACCATTTCATTCTGTTTCTACTAACCTATACCATCTGAGAATTCTAGG
AAGAATAATAAAATCTCGTGTATTCCACAGCAAACTTACATACCATAAAGACAGAATTCCTAAACATCTTGGAGCCGTCTGTCTCTCCCA
TATGATGGCTGTCTGTATATTTTTACTTGGGGTGCTGCTTTATTGGCTTTGAAAACACTGTCAGATAAGCTCAGTAATATGTTACCATGG
GATAAAAATATGTATCCCTGCCTAAGAATAACTTGTGCATTTGTTATGGAAATTTAATTCATATGGTGTTTACAGTACTACTTTTGTAAC
TTCCAGACTTTCTAAAACATTCTGCTTAAAAACCATATAAAATATAATTCCAAAGTCTCTGCTGTCAAGATAGATTCGAGAGAAAGCACG
TGGCCATGTATGCTTTAACCTTAAACTGCATACACATGTAGTGATACCTAGGCTGCATTTAGATCACCGTGTGCTCAGGCCAGGTGTGAA
TCCTGAGGTCCATGGAGGTGCAGAGATGAGATTACTCCTATTCACGTTGAAGTGATTTGCTTTGTTAACAAAAAATTGCAGCTATTGTCT
AGCTTTCATTTTTTTACTGAGAACTTTAAATTAGTCCCCTATTAGAATAGGGTTGCTACTCATCTTTTTTTAAAAACCGAATTTCATCAT
TTATCTAAAGAGAAAATATGCAGAATAACTGGTCTTGTTAAGAGTGCAATATTATATTTTTATGTAAAAATAAAAATTAATTTGGGGGGA
TTATTTATTCAGCATGAAACCTAATATGTATATGTTTGAAATACTTCATAATGTGCATGTTGTAGCAAACATTTCTGTAAATTATCACAA

>8661_8661_4_B3GALNT2-LYST_B3GALNT2_chr1_235647638_ENST00000366600_LYST_chr1_235850347_ENST00000389794_length(amino acids)=479AA_BP=245
MRDRRSGAGSCEEPSRRRRARGRACSEWSLVSRRPSVSALAGPLPLRRDAGEPGSRRGRPMRNWLVLLCPCVLGAALHLWLRLRSPPPAC
ASGAGPADQLALFPQWKSTHYDVVVGVLSARNNHELRNVIRSTWMRHLLQHPTLSQRVLVKFIIGAHGCEVPVEDREDPYSCKLLNITNP
VLNQEIEAFSLSEDTSSGLPEDRVVSVSFRVLYPIVITSLGVFYDANDVGFQRNITVKLYQAEQEVTSCAWVPDSCQLFTGSKCGVITAY
TNRFTSSTPSEIEMETQIHLYGHTEEITSLFVCKPYSILISVSRDGTCIIWDLNRLCYVQSLAGHKSPVTAVSASETSGDIATVCDSAGG
GSDLRLWTVNGDLVGHVHCREIICSVAFSNQPEGVSINVIAGGLENGIVRLWSTWDLKPVREITFPKSNKPIISLTFSCDGHHLYTANSD

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for B3GALNT2-LYST


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for B3GALNT2-LYST


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for B3GALNT2-LYST


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneB3GALNT2C0265221Walker-Warburg congenital muscular dystrophy1CTD_human;ORPHANET
HgeneB3GALNT2C0457133Muscle eye brain disease1CTD_human;ORPHANET
HgeneB3GALNT2C3554638MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYE ANOMALIES), TYPE A, 111GENOMICS_ENGLAND;UNIPROT
TgeneC0007965Chediak-Higashi Syndrome12CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC0001916Albinism3GENOMICS_ENGLAND
TgeneC0242422Parkinsonian Disorders3GENOMICS_ENGLAND
TgeneC4721453Peripheral Nervous System Diseases3GENOMICS_ENGLAND
TgeneC0037772Spastic Paraplegia2GENOMICS_ENGLAND
TgeneC4304022Attenuated Chédiak-Higashi syndrome1ORPHANET