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![]() | Fusion Gene Summary |
![]() | Fusion Gene ORF analysis |
![]() | Fusion Genomic Features |
![]() | Fusion Protein Features |
![]() | Fusion Gene Sequence |
![]() | Fusion Gene PPI analysis |
![]() | Related Drugs |
![]() | Related Diseases |
Fusion gene:CTNNB1-CHEK1 (FusionGDB2 ID:HG1499TG1111) |
Fusion Gene Summary for CTNNB1-CHEK1 |
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Fusion gene information | Fusion gene name: CTNNB1-CHEK1 | Fusion gene ID: hg1499tg1111 | Hgene | Tgene | Gene symbol | CTNNB1 | CHEK1 | Gene ID | 1499 | 1111 |
Gene name | catenin beta 1 | checkpoint kinase 1 | |
Synonyms | CTNNB|EVR7|MRD19|NEDSDV|armadillo | CHK1 | |
Cytomap | ('CTNNB1')('CHEK1') 3p22.1 | 11q24.2 | |
Type of gene | protein-coding | protein-coding | |
Description | catenin beta-1catenin (cadherin-associated protein), beta 1, 88kDa | serine/threonine-protein kinase Chk1CHK1 checkpoint homologCheckpoint, S. pombe, homolog of, 1Chk1-Scell cycle checkpoint kinase | |
Modification date | 20200327 | 20200313 | |
UniProtAcc | . | . | |
Ensembl transtripts involved in fusion gene | ENST00000349496, ENST00000396183, ENST00000396185, ENST00000453024, ENST00000405570, ENST00000471014, | ||
Fusion gene scores | * DoF score | 19 X 14 X 13=3458 | 3 X 3 X 3=27 |
# samples | 21 | 3 | |
** MAII score | log2(21/3458*10)=-4.04147663597616 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: CTNNB1 [Title/Abstract] AND CHEK1 [Title/Abstract] AND fusion [Title/Abstract] | ||
Most frequent breakpoint | CTNNB1(41241161)-CHEK1(125496643), # samples:1 | ||
Anticipated loss of major functional domain due to fusion event. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
Hgene | CTNNB1 | GO:0000209 | protein polyubiquitination | 29374064 |
Hgene | CTNNB1 | GO:0008285 | negative regulation of cell proliferation | 12970740 |
Hgene | CTNNB1 | GO:0030997 | regulation of centriole-centriole cohesion | 18086858 |
Hgene | CTNNB1 | GO:0032355 | response to estradiol | 15304487 |
Hgene | CTNNB1 | GO:0033234 | negative regulation of protein sumoylation | 22155184 |
Hgene | CTNNB1 | GO:0043065 | positive regulation of apoptotic process | 12651860|12970740 |
Hgene | CTNNB1 | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 29374064 |
Hgene | CTNNB1 | GO:0043525 | positive regulation of neuron apoptotic process | 19591802 |
Hgene | CTNNB1 | GO:0045893 | positive regulation of transcription, DNA-templated | 12970740|18787224 |
Hgene | CTNNB1 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 9065402|11751639|12651860|14660579|18193033 |
Hgene | CTNNB1 | GO:0060070 | canonical Wnt signaling pathway | 10644691|12937339|19187541 |
Hgene | CTNNB1 | GO:0071681 | cellular response to indole-3-methanol | 10868478 |
Hgene | CTNNB1 | GO:0090279 | regulation of calcium ion import | 19996314 |
Hgene | CTNNB1 | GO:1904798 | positive regulation of core promoter binding | 22723415 |
Hgene | CTNNB1 | GO:2000008 | regulation of protein localization to cell surface | 19996314 |
Tgene | CHEK1 | GO:0000077 | DNA damage checkpoint | 16963448 |
Tgene | CHEK1 | GO:0006915 | apoptotic process | 23028632 |
Tgene | CHEK1 | GO:0006975 | DNA damage induced protein phosphorylation | 16963448 |
Tgene | CHEK1 | GO:0010569 | regulation of double-strand break repair via homologous recombination | 15665856 |
Tgene | CHEK1 | GO:0018107 | peptidyl-threonine phosphorylation | 15665856 |
Tgene | CHEK1 | GO:0045787 | positive regulation of cell cycle | 26296656 |
Tgene | CHEK1 | GO:0045839 | negative regulation of mitotic nuclear division | 15311285 |
Tgene | CHEK1 | GO:0046602 | regulation of mitotic centrosome separation | 15311285 |
![]() * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChimerDB4 | ESCA | TCGA-L5-A4OW | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
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Fusion Gene ORF analysis for CTNNB1-CHEK1 |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
5UTR-3UTR | ENST00000349496 | ENST00000532449 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-3UTR | ENST00000396183 | ENST00000532449 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-3UTR | ENST00000396185 | ENST00000532449 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-3UTR | ENST00000453024 | ENST00000532449 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000349496 | ENST00000278916 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000349496 | ENST00000427383 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000349496 | ENST00000428830 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000349496 | ENST00000438015 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000349496 | ENST00000524737 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000349496 | ENST00000534070 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000349496 | ENST00000544373 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000396183 | ENST00000278916 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000396183 | ENST00000427383 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000396183 | ENST00000428830 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000396183 | ENST00000438015 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000396183 | ENST00000524737 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000396183 | ENST00000534070 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000396183 | ENST00000544373 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000396185 | ENST00000278916 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000396185 | ENST00000427383 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000396185 | ENST00000428830 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000396185 | ENST00000438015 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000396185 | ENST00000524737 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000396185 | ENST00000534070 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000396185 | ENST00000544373 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000453024 | ENST00000278916 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000453024 | ENST00000427383 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000453024 | ENST00000428830 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000453024 | ENST00000438015 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000453024 | ENST00000524737 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000453024 | ENST00000534070 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
5UTR-5UTR | ENST00000453024 | ENST00000544373 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
intron-3UTR | ENST00000405570 | ENST00000532449 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
intron-3UTR | ENST00000471014 | ENST00000532449 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
intron-5UTR | ENST00000405570 | ENST00000278916 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
intron-5UTR | ENST00000405570 | ENST00000427383 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
intron-5UTR | ENST00000405570 | ENST00000428830 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
intron-5UTR | ENST00000405570 | ENST00000438015 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
intron-5UTR | ENST00000405570 | ENST00000524737 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
intron-5UTR | ENST00000405570 | ENST00000534070 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
intron-5UTR | ENST00000405570 | ENST00000544373 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
intron-5UTR | ENST00000471014 | ENST00000278916 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
intron-5UTR | ENST00000471014 | ENST00000427383 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
intron-5UTR | ENST00000471014 | ENST00000428830 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
intron-5UTR | ENST00000471014 | ENST00000438015 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
intron-5UTR | ENST00000471014 | ENST00000524737 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
intron-5UTR | ENST00000471014 | ENST00000534070 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
intron-5UTR | ENST00000471014 | ENST00000544373 | CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496643 | + |
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Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
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Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
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Fusion Genomic Features for CTNNB1-CHEK1 |
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Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496642 | + | 3.66E-06 | 0.9999963 |
CTNNB1 | chr3 | 41241161 | + | CHEK1 | chr11 | 125496642 | + | 3.66E-06 | 0.9999963 |
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Fusion Protein Features for CTNNB1-CHEK1 |
![]() Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:41241161/:125496643) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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Hgene | Tgene |
. | . |
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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Fusion Gene Sequence for CTNNB1-CHEK1 |
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Fusion Gene PPI Analysis for CTNNB1-CHEK1 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for CTNNB1-CHEK1 |
![]() (DrugBank Version 5.1.8 2021-05-08) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for CTNNB1-CHEK1 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | CTNNB1 | C0007102 | Malignant tumor of colon | 9 | CTD_human |
Hgene | CTNNB1 | C0009375 | Colonic Neoplasms | 9 | CTD_human |
Hgene | CTNNB1 | C3554449 | MENTAL RETARDATION, AUTOSOMAL DOMINANT 19 | 6 | CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT |
Hgene | CTNNB1 | C0009402 | Colorectal Carcinoma | 5 | CTD_human;UNIPROT |
Hgene | CTNNB1 | C2239176 | Liver carcinoma | 5 | CGI;CTD_human;GENOMICS_ENGLAND;UNIPROT |
Hgene | CTNNB1 | C0009404 | Colorectal Neoplasms | 4 | CTD_human |
Hgene | CTNNB1 | C0001418 | Adenocarcinoma | 3 | CTD_human |
Hgene | CTNNB1 | C0019207 | Hepatoma, Morris | 3 | CTD_human |
Hgene | CTNNB1 | C0019208 | Hepatoma, Novikoff | 3 | CTD_human |
Hgene | CTNNB1 | C0023904 | Liver Neoplasms, Experimental | 3 | CTD_human |
Hgene | CTNNB1 | C0086404 | Experimental Hepatoma | 3 | CTD_human |
Hgene | CTNNB1 | C0205641 | Adenocarcinoma, Basal Cell | 3 | CTD_human |
Hgene | CTNNB1 | C0205642 | Adenocarcinoma, Oxyphilic | 3 | CTD_human |
Hgene | CTNNB1 | C0205643 | Carcinoma, Cribriform | 3 | CTD_human |
Hgene | CTNNB1 | C0205644 | Carcinoma, Granular Cell | 3 | CTD_human |
Hgene | CTNNB1 | C0205645 | Adenocarcinoma, Tubular | 3 | CTD_human |
Hgene | CTNNB1 | C0206711 | Pilomatrixoma | 3 | CTD_human;ORPHANET;UNIPROT |
Hgene | CTNNB1 | C1879526 | Aberrant Crypt Foci | 3 | CTD_human |
Hgene | CTNNB1 | C0001430 | Adenoma | 2 | CTD_human |
Hgene | CTNNB1 | C0006142 | Malignant neoplasm of breast | 2 | CTD_human |
Hgene | CTNNB1 | C0023903 | Liver neoplasms | 2 | CTD_human |
Hgene | CTNNB1 | C0025149 | Medulloblastoma | 2 | CGI;CTD_human;UNIPROT |
Hgene | CTNNB1 | C0027626 | Neoplasm Invasiveness | 2 | CTD_human |
Hgene | CTNNB1 | C0027708 | Nephroblastoma | 2 | CTD_human |
Hgene | CTNNB1 | C0033578 | Prostatic Neoplasms | 2 | CTD_human |
Hgene | CTNNB1 | C0036341 | Schizophrenia | 2 | PSYGENET |
Hgene | CTNNB1 | C0205646 | Adenoma, Basal Cell | 2 | CTD_human |
Hgene | CTNNB1 | C0205647 | Follicular adenoma | 2 | CTD_human |
Hgene | CTNNB1 | C0205648 | Adenoma, Microcystic | 2 | CTD_human |
Hgene | CTNNB1 | C0205649 | Adenoma, Monomorphic | 2 | CTD_human |
Hgene | CTNNB1 | C0205650 | Papillary adenoma | 2 | CTD_human |
Hgene | CTNNB1 | C0205651 | Adenoma, Trabecular | 2 | CTD_human |
Hgene | CTNNB1 | C0235874 | Disease Exacerbation | 2 | CTD_human |
Hgene | CTNNB1 | C0345904 | Malignant neoplasm of liver | 2 | CTD_human |
Hgene | CTNNB1 | C0376358 | Malignant neoplasm of prostate | 2 | CTD_human |
Hgene | CTNNB1 | C0678222 | Breast Carcinoma | 2 | CTD_human |
Hgene | CTNNB1 | C1140680 | Malignant neoplasm of ovary | 2 | CGI;CTD_human;UNIPROT |
Hgene | CTNNB1 | C1257931 | Mammary Neoplasms, Human | 2 | CTD_human |
Hgene | CTNNB1 | C1458155 | Mammary Neoplasms | 2 | CTD_human |
Hgene | CTNNB1 | C2930471 | Bilateral Wilms Tumor | 2 | CTD_human |
Hgene | CTNNB1 | C4539767 | EXUDATIVE VITREORETINOPATHY 7 | 2 | GENOMICS_ENGLAND;UNIPROT |
Hgene | CTNNB1 | C4704874 | Mammary Carcinoma, Human | 2 | CTD_human |
Hgene | CTNNB1 | C0000772 | Multiple congenital anomalies | 1 | CTD_human |
Hgene | CTNNB1 | C0001624 | Adrenal Gland Neoplasms | 1 | CTD_human |
Hgene | CTNNB1 | C0007193 | Cardiomyopathy, Dilated | 1 | CTD_human |
Hgene | CTNNB1 | C0007528 | Cecal Neoplasms | 1 | CTD_human |
Hgene | CTNNB1 | C0007621 | Neoplastic Cell Transformation | 1 | CTD_human |
Hgene | CTNNB1 | C0007873 | Uterine Cervical Neoplasm | 1 | CTD_human |
Hgene | CTNNB1 | C0010276 | Craniopharyngioma | 1 | CTD_human;ORPHANET |
Hgene | CTNNB1 | C0014518 | Toxic Epidermal Necrolysis | 1 | CTD_human |
Hgene | CTNNB1 | C0016059 | Fibrosis | 1 | CTD_human |
Hgene | CTNNB1 | C0018923 | Hemangiosarcoma | 1 | CTD_human |
Hgene | CTNNB1 | C0019193 | Hepatitis, Toxic | 1 | CTD_human |
Hgene | CTNNB1 | C0021841 | Intestinal Neoplasms | 1 | CTD_human |
Hgene | CTNNB1 | C0023890 | Liver Cirrhosis | 1 | CTD_human |
Hgene | CTNNB1 | C0024121 | Lung Neoplasms | 1 | CTD_human |
Hgene | CTNNB1 | C0026846 | Muscular Atrophy | 1 | CTD_human |
Hgene | CTNNB1 | C0027627 | Neoplasm Metastasis | 1 | CTD_human |
Hgene | CTNNB1 | C0027746 | Nerve Degeneration | 1 | CTD_human |
Hgene | CTNNB1 | C0030297 | Pancreatic Neoplasm | 1 | CTD_human |
Hgene | CTNNB1 | C0031149 | Peritoneal Neoplasms | 1 | CTD_human |
Hgene | CTNNB1 | C0038325 | Stevens-Johnson Syndrome | 1 | CTD_human |
Hgene | CTNNB1 | C0149721 | Left Ventricular Hypertrophy | 1 | CTD_human |
Hgene | CTNNB1 | C0151744 | Myocardial Ischemia | 1 | CTD_human |
Hgene | CTNNB1 | C0153437 | Malignant neoplasm of cecum | 1 | CTD_human |
Hgene | CTNNB1 | C0206624 | Hepatoblastoma | 1 | CGI;CTD_human |
Hgene | CTNNB1 | C0206669 | Hepatocellular Adenoma | 1 | CTD_human |
Hgene | CTNNB1 | C0206686 | Adrenocortical carcinoma | 1 | CTD_human |
Hgene | CTNNB1 | C0232347 | No-Reflow Phenomenon | 1 | CTD_human |
Hgene | CTNNB1 | C0239946 | Fibrosis, Liver | 1 | CTD_human |
Hgene | CTNNB1 | C0242379 | Malignant neoplasm of lung | 1 | CTD_human |
Hgene | CTNNB1 | C0242698 | Ventricular Dysfunction, Left | 1 | CTD_human |
Hgene | CTNNB1 | C0270948 | Neurogenic Muscular Atrophy | 1 | CTD_human |
Hgene | CTNNB1 | C0278875 | Adult Craniopharyngioma | 1 | CTD_human |
Hgene | CTNNB1 | C0279606 | Childhood Hepatocellular Carcinoma | 1 | ORPHANET |
Hgene | CTNNB1 | C0279607 | Adult Hepatocellular Carcinoma | 1 | ORPHANET |
Hgene | CTNNB1 | C0334634 | Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse | 1 | CTD_human |
Hgene | CTNNB1 | C0339539 | Familial Exudative Vitreoretinopathy | 1 | ORPHANET |
Hgene | CTNNB1 | C0342649 | Vascular calcification | 1 | CTD_human |
Hgene | CTNNB1 | C0345967 | Malignant mesothelioma | 1 | CTD_human |
Hgene | CTNNB1 | C0346627 | Intestinal Cancer | 1 | CTD_human |
Hgene | CTNNB1 | C0346647 | Malignant neoplasm of pancreas | 1 | CTD_human |
Hgene | CTNNB1 | C0346990 | Carcinomatosis of peritoneal cavity | 1 | CTD_human |
Hgene | CTNNB1 | C0376634 | Craniofacial Abnormalities | 1 | CTD_human |
Hgene | CTNNB1 | C0431128 | Papillary craniopharyngioma | 1 | CTD_human |
Hgene | CTNNB1 | C0431129 | Adamantinous Craniopharyngioma | 1 | CTD_human |
Hgene | CTNNB1 | C0431350 | Primary microcephaly | 1 | GENOMICS_ENGLAND |
Hgene | CTNNB1 | C0600519 | Ventricular Remodeling | 1 | CTD_human |
Hgene | CTNNB1 | C0600520 | Left Ventricle Remodeling | 1 | CTD_human |
Hgene | CTNNB1 | C0750887 | Adrenal Cancer | 1 | CTD_human |
Hgene | CTNNB1 | C0751061 | Craniopharyngioma, Child | 1 | CTD_human |
Hgene | CTNNB1 | C0751958 | Lymphoma, Lymphocytic, Intermediate | 1 | CTD_human |
Hgene | CTNNB1 | C0860207 | Drug-Induced Liver Disease | 1 | CTD_human |
Hgene | CTNNB1 | C0919267 | ovarian neoplasm | 1 | CGI;CTD_human |
Hgene | CTNNB1 | C1262760 | Hepatitis, Drug-Induced | 1 | CTD_human |
Hgene | CTNNB1 | C1274933 | Drug-Induced Stevens Johnson Syndrome | 1 | CTD_human |
Hgene | CTNNB1 | C1449563 | Cardiomyopathy, Familial Idiopathic | 1 | CTD_human |
Hgene | CTNNB1 | C1535926 | Neurodevelopmental Disorders | 1 | CTD_human |
Hgene | CTNNB1 | C1623038 | Cirrhosis | 1 | CTD_human |
Hgene | CTNNB1 | C1851402 | Exudative vitreoretinopathy 1 | 1 | ORPHANET |
Hgene | CTNNB1 | C2713615 | Slow-Flow Phenomenon | 1 | CTD_human |
Hgene | CTNNB1 | C3658290 | Drug-Induced Acute Liver Injury | 1 | CTD_human |
Hgene | CTNNB1 | C3658301 | Mycoplasma-Induced Stevens-Johnson Syndrome | 1 | CTD_human |
Hgene | CTNNB1 | C3658302 | Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum | 1 | CTD_human |
Hgene | CTNNB1 | C4048328 | cervical cancer | 1 | CTD_human |
Hgene | CTNNB1 | C4277682 | Chemical and Drug Induced Liver Injury | 1 | CTD_human |
Hgene | CTNNB1 | C4279912 | Chemically-Induced Liver Toxicity | 1 | CTD_human |
Tgene | C0006142 | Malignant neoplasm of breast | 1 | CTD_human | |
Tgene | C0032578 | Polyploidy | 1 | CTD_human | |
Tgene | C0036341 | Schizophrenia | 1 | PSYGENET | |
Tgene | C0678222 | Breast Carcinoma | 1 | CTD_human | |
Tgene | C1257931 | Mammary Neoplasms, Human | 1 | CTD_human | |
Tgene | C1458155 | Mammary Neoplasms | 1 | CTD_human | |
Tgene | C4704874 | Mammary Carcinoma, Human | 1 | CTD_human |