Fusion Gene Studies
in Kim Lab

FusionBase FusionGDB FusionGDB2 FusionPDB FusionNeoAntigen FusionAI FusionNW FGviewer Publication Contact
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact

Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:CTNND1-AMACR (FusionGDB2 ID:HG1500TG23600)

Fusion Gene Summary for CTNND1-AMACR

check button Fusion gene summary
Fusion gene informationFusion gene name: CTNND1-AMACR
Fusion gene ID: hg1500tg23600
HgeneTgene
Gene symbol

CTNND1

AMACR

Gene ID

1500

23600

Gene namecatenin delta 1alpha-methylacyl-CoA racemase
SynonymsBCDS2|CAS|CTNND|P120CAS|P120CTN|p120|p120(CAS)|p120(CTN)AMACRD|CBAS4|P504S|RACE|RM
Cytomap('CTNND1')('AMACR')

11q12.1

5p13.2

Type of geneprotein-codingprotein-coding
Descriptioncatenin delta-1cadherin-associated Src substratecatenin (cadherin-associated protein), delta 1p120 cateninalpha-methylacyl-CoA racemase2-methylacyl-CoA racemase
Modification date2020032720200313
UniProtAcc.

Q9UHK6

Ensembl transtripts involved in fusion geneENST00000358694, ENST00000360682, 
ENST00000361332, ENST00000361391, 
ENST00000361796, ENST00000399050, 
ENST00000415361, ENST00000426142, 
ENST00000428599, ENST00000525902, 
ENST00000526357, ENST00000526772, 
ENST00000526938, ENST00000527467, 
ENST00000528232, ENST00000528621, 
ENST00000529526, ENST00000529873, 
ENST00000529986, ENST00000530094, 
ENST00000530748, ENST00000531014, 
ENST00000532245, ENST00000532463, 
ENST00000532649, ENST00000532787, 
ENST00000532844, ENST00000533667, 
ENST00000534579, ENST00000399039, 
ENST00000524630, ENST00000529919, 
Fusion gene scores* DoF score29 X 18 X 15=783028 X 3 X 4=336
# samples 3523
** MAII scorelog2(35/7830*10)=-4.48358548034607
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(23/336*10)=-0.546827371834385
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CTNND1 [Title/Abstract] AND AMACR [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCTNND1(57529518)-AMACR(34006004), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCTNND1

GO:0099072

regulation of postsynaptic membrane neurotransmitter receptor levels

18602475

TgeneAMACR

GO:0008206

bile acid metabolic process

10655068



check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-KC-A7FDCTNND1chr11

57529518

+AMACRchr5

34006004

-


Top

Fusion Gene ORF analysis for CTNND1-AMACR

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000358694ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000358694ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000360682ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000360682ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000361332ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000361332ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000361391ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000361391ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000361796ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000361796ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000399050ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000399050ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000415361ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000415361ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000426142ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000426142ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000428599ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000428599ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000525902ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000525902ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000526357ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000526357ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000526772ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000526772ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000526938ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000526938ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000527467ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000527467ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000528232ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000528232ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000528621ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000528621ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000529526ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000529526ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000529873ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000529873ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000529986ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000529986ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000530094ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000530094ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000530748ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000530748ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000531014ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000531014ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000532245ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000532245ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000532463ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000532463ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000532649ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000532649ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000532787ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000532787ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000532844ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000532844ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000533667ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000533667ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000534579ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-3CDSENST00000534579ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000358694ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000358694ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000358694ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000358694ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000358694ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000358694ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000358694ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000360682ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000360682ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000360682ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000360682ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000360682ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000360682ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000360682ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361332ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361332ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361332ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361332ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361332ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361332ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361332ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361391ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361391ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361391ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361391ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361391ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361391ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361391ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361796ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361796ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361796ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361796ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361796ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361796ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000361796ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000399050ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000399050ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000399050ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000399050ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000399050ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000399050ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000399050ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000415361ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000415361ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000415361ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000415361ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000415361ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000415361ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000415361ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000426142ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000426142ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000426142ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000426142ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000426142ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000426142ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000426142ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000428599ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000428599ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000428599ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000428599ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000428599ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000428599ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000428599ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000525902ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000525902ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000525902ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000525902ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000525902ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000525902ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000525902ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526357ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526357ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526357ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526357ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526357ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526357ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526357ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526772ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526772ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526772ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526772ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526772ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526772ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526772ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526938ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526938ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526938ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526938ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526938ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526938ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000526938ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000527467ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000527467ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000527467ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000527467ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000527467ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000527467ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000527467ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000528232ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000528232ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000528232ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000528232ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000528232ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000528232ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000528232ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000528621ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000528621ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000528621ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000528621ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000528621ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000528621ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000528621ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529526ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529526ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529526ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529526ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529526ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529526ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529526ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529873ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529873ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529873ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529873ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529873ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529873ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529873ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529986ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529986ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529986ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529986ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529986ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529986ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000529986ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000530094ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000530094ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000530094ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000530094ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000530094ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000530094ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000530094ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000530748ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000530748ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000530748ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000530748ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000530748ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000530748ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000530748ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000531014ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000531014ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000531014ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000531014ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000531014ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000531014ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000531014ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532245ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532245ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532245ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532245ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532245ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532245ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532245ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532463ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532463ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532463ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532463ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532463ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532463ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532463ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532649ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532649ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532649ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532649ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532649ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532649ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532649ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532787ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532787ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532787ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532787ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532787ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532787ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532787ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532844ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532844ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532844ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532844ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532844ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532844ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000532844ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000533667ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000533667ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000533667ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000533667ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000533667ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000533667ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000533667ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000534579ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000534579ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000534579ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000534579ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000534579ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000534579ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
5UTR-5UTRENST00000534579ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-3CDSENST00000399039ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-3CDSENST00000399039ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-3CDSENST00000524630ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-3CDSENST00000524630ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-3CDSENST00000529919ENST00000335606CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-3CDSENST00000529919ENST00000382072CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000399039ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000399039ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000399039ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000399039ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000399039ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000399039ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000399039ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000524630ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000524630ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000524630ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000524630ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000524630ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000524630ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000524630ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000529919ENST00000382068CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000529919ENST00000382085CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000529919ENST00000426255CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000529919ENST00000441713CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000529919ENST00000502637CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000529919ENST00000512079CTNND1chr11

57529518

+AMACRchr5

34006004

-
intron-5UTRENST00000529919ENST00000514195CTNND1chr11

57529518

+AMACRchr5

34006004

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

Top

Fusion Genomic Features for CTNND1-AMACR


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)


Top

Fusion Protein Features for CTNND1-AMACR


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:57529518/:34006004)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AMACR

Q9UHK6

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters (PubMed:7649182, PubMed:10655068, PubMed:11060359). Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2-(4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs (PubMed:7649182, PubMed:10655068, PubMed:11060359). {ECO:0000269|PubMed:10655068, ECO:0000269|PubMed:11060359, ECO:0000269|PubMed:7649182}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

Fusion Gene Sequence for CTNND1-AMACR


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

Top

Fusion Gene PPI Analysis for CTNND1-AMACR


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for CTNND1-AMACR


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for CTNND1-AMACR


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCTNND1C0008925Cleft Palate1GENOMICS_ENGLAND
HgeneCTNND1C1861536Blepharo-cheilo-dontic syndrome1ORPHANET
TgeneC0033578Prostatic Neoplasms3CTD_human
TgeneC0376358Malignant neoplasm of prostate3CTD_human
TgeneC1858328Bile acid synthesis defect, congenital, 43CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC3280428Alpha-Methylacyl-CoA Racemase Deficiency3CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC0023893Liver Cirrhosis, Experimental2CTD_human
TgeneC0001430Adenoma1CTD_human
TgeneC0009402Colorectal Carcinoma1CTD_human
TgeneC0009404Colorectal Neoplasms1CTD_human
TgeneC0011195Dejerine-Sottas Disease (disorder)1CTD_human
TgeneC0019816Hereditary, Type VII, Motor and Sensory Neuropathy1CTD_human
TgeneC0023895Liver diseases1CTD_human
TgeneC0027888Hereditary Motor and Sensory Neuropathies1CTD_human
TgeneC0036341Schizophrenia1PSYGENET
TgeneC0086565Liver Dysfunction1CTD_human
TgeneC0205646Adenoma, Basal Cell1CTD_human
TgeneC0205647Follicular adenoma1CTD_human
TgeneC0205648Adenoma, Microcystic1CTD_human
TgeneC0205649Adenoma, Monomorphic1CTD_human
TgeneC0205650Papillary adenoma1CTD_human
TgeneC0205651Adenoma, Trabecular1CTD_human