Fusion Gene Studies
in Kim Lab

FusionBase FusionGDB FusionGDB2 FusionPDB FusionNeoAntigen FusionAI FusionNW FGviewer Publication Contact
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:CTNND1-TMX2 (FusionGDB2 ID:HG1500TG51075)

Fusion Gene Summary for CTNND1-TMX2

check button Fusion gene summary
Fusion gene informationFusion gene name: CTNND1-TMX2
Fusion gene ID: hg1500tg51075
HgeneTgene
Gene symbol

CTNND1

TMX2

Gene ID

1500

51075

Gene namecatenin delta 1thioredoxin related transmembrane protein 2
SynonymsBCDS2|CAS|CTNND|P120CAS|P120CTN|p120|p120(CAS)|p120(CTN)CGI-31|NEDMCMS|PDIA12|PIG26|TXNDC14
Cytomap('CTNND1')('TMX2')

11q12.1

11q12.1

Type of geneprotein-codingprotein-coding
Descriptioncatenin delta-1cadherin-associated Src substratecatenin (cadherin-associated protein), delta 1p120 cateninthioredoxin-related transmembrane protein 2cell proliferation-inducing gene 26 proteingrowth-inhibiting gene 11protein disulfide isomerase family A, member 12thioredoxin domain-containing protein 14
Modification date2020032720200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000358694, ENST00000360682, 
ENST00000361332, ENST00000361391, 
ENST00000361796, ENST00000399039, 
ENST00000399050, ENST00000415361, 
ENST00000426142, ENST00000428599, 
ENST00000524630, ENST00000525902, 
ENST00000526357, ENST00000526772, 
ENST00000527467, ENST00000528232, 
ENST00000528621, ENST00000529526, 
ENST00000529873, ENST00000529919, 
ENST00000529986, ENST00000530094, 
ENST00000530748, ENST00000531014, 
ENST00000532245, ENST00000532463, 
ENST00000532649, ENST00000532787, 
ENST00000532844, ENST00000533667, 
ENST00000534579, ENST00000526938, 
ENST00000358694, ENST00000360682, 
ENST00000361332, ENST00000361391, 
ENST00000361796, ENST00000399039, 
ENST00000399050, ENST00000415361, 
ENST00000426142, ENST00000428599, 
ENST00000524630, ENST00000526357, 
ENST00000526938, ENST00000528232, 
ENST00000528621, ENST00000529526, 
ENST00000529919, ENST00000529986, 
ENST00000530094, ENST00000530748, 
ENST00000532245, ENST00000532463, 
ENST00000532649, ENST00000532787, 
ENST00000532844, ENST00000534579, 
ENST00000525902, ENST00000526772, 
ENST00000527467, ENST00000529873, 
ENST00000531014, ENST00000533667, 
Fusion gene scores* DoF score29 X 18 X 15=78301 X 2 X 4=8
# samples 354
** MAII scorelog2(35/7830*10)=-4.48358548034607
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/8*10)=2.32192809488736
Context

PubMed: CTNND1 [Title/Abstract] AND TMX2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCTNND1(57529518)-TMX2(57505080), # samples:3
Anticipated loss of major functional domain due to fusion event.TMX2-CTNND1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
TMX2-CTNND1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CTNND1-TMX2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CTNND1-TMX2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CTNND1-TMX2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CTNND1-TMX2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
TMX2-CTNND1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
TMX2-CTNND1 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
TMX2-CTNND1 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCTNND1

GO:0099072

regulation of postsynaptic membrane neurotransmitter receptor levels

18602475


check buttonFusion gene breakpoints across CTNND1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across TMX2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-4Z-AA7QCTNND1chr11

57584356

+TMX2chr11

57505080

+
ChimerDB4BRCATCGA-AR-A1AH-01ACTNND1chr11

57529518

-TMX2chr11

57505080

+
ChimerDB4BRCATCGA-AR-A1AHCTNND1chr11

57529518

+TMX2chr11

57505079

+
ChimerDB4KIRCTCGA-BP-4962-01ACTNND1chr11

57529518

-TMX2chr11

57505080

+
ChimerDB4KIRCTCGA-BP-4962-01ACTNND1chr11

57529518

+TMX2chr11

57505080

+
ChimerDB4OVTCGA-31-1951CTNND1chr11

57529518

+TMX2chr11

57505079

+
ChimerDB4OVTCGA-31-1951CTNND1chr11

57529591

+TMX2chr11

57505079

+
ChimerDB4OVTCGA-31-1951CTNND1chr11

57561553

+TMX2chr11

57505079

+


Top

Fusion Gene ORF analysis for CTNND1-TMX2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000358694ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000358694ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000360682ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000360682ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000361332ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000361332ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000361391ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000361391ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000361796ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000361796ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000399039ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000399039ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000399050ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000399050ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000415361ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000415361ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000426142ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000426142ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000428599ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000428599ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000524630ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000524630ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000525902ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000525902ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000526357ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000526357ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000526772ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000526772ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000527467ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000527467ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000528232ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000528232ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000528621ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000528621ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000529526ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000529526ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000529873ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000529873ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000529919ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000529919ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000529986ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000529986ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000530094ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000530094ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000530748ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000530748ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000531014ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000531014ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000532245ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000532245ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000532463ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000532463ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000532649ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000532649ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000532787ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000532787ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000532844ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000532844ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000533667ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000533667ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000534579ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
3UTR-3CDSENST00000534579ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
5UTR-3CDSENST00000358694ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000358694ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000358694ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000358694ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000360682ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000360682ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000360682ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
5UTR-3CDSENST00000360682ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000360682ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000360682ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
5UTR-3CDSENST00000361332ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000361332ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000361332ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
5UTR-3CDSENST00000361332ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000361332ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000361332ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
5UTR-3CDSENST00000361391ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000361391ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000361391ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
5UTR-3CDSENST00000361391ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000361391ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000361391ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
5UTR-3CDSENST00000361796ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000361796ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000361796ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
5UTR-3CDSENST00000361796ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000361796ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000361796ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
5UTR-3CDSENST00000399050ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000399050ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000399050ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
5UTR-3CDSENST00000399050ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000399050ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000399050ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
5UTR-3CDSENST00000415361ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000415361ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000415361ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
5UTR-3CDSENST00000415361ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000415361ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000415361ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
5UTR-3CDSENST00000426142ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000426142ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000426142ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
5UTR-3CDSENST00000426142ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
5UTR-3CDSENST00000426142ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000426142ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000426142ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
5UTR-3CDSENST00000426142ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
5UTR-3CDSENST00000428599ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000428599ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000428599ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000428599ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000525902ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000525902ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000525902ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000525902ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000526357ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000526357ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000526357ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000526357ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000526772ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000526772ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000526772ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000526772ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000526938ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000526938ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000526938ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000526938ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000527467ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000527467ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000527467ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000527467ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000528232ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000528232ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000528232ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
5UTR-3CDSENST00000528232ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000528232ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000528232ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
5UTR-3CDSENST00000528621ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000528621ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000528621ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000528621ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000529526ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000529526ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000529526ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
5UTR-3CDSENST00000529526ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000529526ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000529526ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
5UTR-3CDSENST00000529873ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000529873ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000529873ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000529873ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000529986ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000529986ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000529986ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
5UTR-3CDSENST00000529986ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000529986ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000529986ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
5UTR-3CDSENST00000530094ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000530094ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000530094ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
5UTR-3CDSENST00000530094ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000530094ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000530094ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
5UTR-3CDSENST00000530748ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000530748ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000530748ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000530748ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000531014ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000531014ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000531014ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000531014ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000532245ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000532245ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000532245ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000532245ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000532463ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000532463ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000532463ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
5UTR-3CDSENST00000532463ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000532463ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000532463ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
5UTR-3CDSENST00000532649ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000532649ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000532649ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000532649ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000532787ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000532787ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000532787ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
5UTR-3CDSENST00000532787ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000532787ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000532787ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
5UTR-3CDSENST00000532844ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000532844ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000532844ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000532844ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000533667ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000533667ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000533667ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000533667ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000534579ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000534579ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
5UTR-3CDSENST00000534579ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
5UTR-3CDSENST00000534579ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
In-frameENST00000358694ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000358694ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000360682ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000360682ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000361332ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000361332ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000361391ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000361391ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000361796ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000361796ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000399039ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000399039ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000399050ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000399050ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000428599ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000428599ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000524630ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000524630ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000526357ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000526357ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000526938ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000526938ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000528621ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000528621ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000529526ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000529526ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000529873ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000529873ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000529919ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000529919ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000530748ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000530748ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000532649ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000532649ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000532844ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000532844ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000534579ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
In-frameENST00000534579ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
intron-3CDSENST00000358694ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000358694ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000399039ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
intron-3CDSENST00000399039ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
intron-3CDSENST00000399039ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000399039ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
intron-3CDSENST00000399039ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
intron-3CDSENST00000399039ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000415361ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000415361ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000428599ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000428599ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000524630ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
intron-3CDSENST00000524630ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
intron-3CDSENST00000524630ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000524630ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
intron-3CDSENST00000524630ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
intron-3CDSENST00000524630ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000525902ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000525902ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
intron-3CDSENST00000525902ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000525902ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
intron-3CDSENST00000526357ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000526357ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000526772ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000526772ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
intron-3CDSENST00000526772ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000526772ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
intron-3CDSENST00000526938ENST00000278422CTNND1chr11

57584356

+TMX2chr11

57505080

+
intron-3CDSENST00000526938ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000526938ENST00000378312CTNND1chr11

57584356

+TMX2chr11

57505080

+
intron-3CDSENST00000526938ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000527467ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000527467ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
intron-3CDSENST00000527467ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000527467ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
intron-3CDSENST00000528232ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000528232ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000528621ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000528621ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000529873ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000529873ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000529919ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505079

+
intron-3CDSENST00000529919ENST00000278422CTNND1chr11

57529518

+TMX2chr11

57505080

+
intron-3CDSENST00000529919ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000529919ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505079

+
intron-3CDSENST00000529919ENST00000378312CTNND1chr11

57529518

+TMX2chr11

57505080

+
intron-3CDSENST00000529919ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000529986ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000529986ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000530094ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000530094ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000530748ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000530748ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000531014ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000531014ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
intron-3CDSENST00000531014ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000531014ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
intron-3CDSENST00000532245ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000532245ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
intron-3CDSENST00000532245ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000532245ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
intron-3CDSENST00000532463ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000532463ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000532649ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000532649ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000532787ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000532787ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000532844ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000532844ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000533667ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000533667ENST00000278422CTNND1chr11

57561553

+TMX2chr11

57505079

+
intron-3CDSENST00000533667ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000533667ENST00000378312CTNND1chr11

57561553

+TMX2chr11

57505079

+
intron-3CDSENST00000534579ENST00000278422CTNND1chr11

57529591

+TMX2chr11

57505079

+
intron-3CDSENST00000534579ENST00000378312CTNND1chr11

57529591

+TMX2chr11

57505079

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

Top

Fusion Genomic Features for CTNND1-TMX2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CTNND1chr1157529591+TMX2chr1157505079+4.04E-050.9999596
CTNND1chr1157529518+TMX2chr1157505079+6.47E-060.99999356
CTNND1chr1157529518+TMX2chr1157505079+6.47E-060.99999356
CTNND1chr1157529518+TMX2chr1157505079+6.47E-060.99999356
CTNND1chr1157561553+TMX2chr1157505079+1.82E-060.9999982
CTNND1chr1157529591+TMX2chr1157505079+4.04E-050.9999596
CTNND1chr1157529518+TMX2chr1157505079+6.47E-060.99999356
CTNND1chr1157529518+TMX2chr1157505079+6.47E-060.99999356
CTNND1chr1157529518+TMX2chr1157505079+6.47E-060.99999356
CTNND1chr1157561553+TMX2chr1157505079+1.82E-060.9999982

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for CTNND1-TMX2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:57529518/chr11:57505080)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCTNND1chr11:57561553chr11:57505079ENST00000358694+41910_4689934.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000360682+42010_4689948.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361332+42010_4689963.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361391+41910_4689942.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361796+41910_4689934.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000399050+42110_4689969.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000428599+31810_4689934.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000524630+41910_4689934.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526938+31810_4689919.0Coiled coilOntology_term=ECO:0000255
TgeneTMX2chr11:57561553chr11:57505079ENST0000027842208114_26963297.0DomainThioredoxin
TgeneTMX2chr11:57561553chr11:57505079ENST0000037831207114_26963259.0DomainThioredoxin
TgeneTMX2chr11:57561553chr11:57505079ENST0000027842208293_29663297.0MotifDi-lysine motif
TgeneTMX2chr11:57561553chr11:57505079ENST0000037831207293_29663259.0MotifDi-lysine motif
TgeneTMX2chr11:57561553chr11:57505079ENST0000027842208126_29663297.0Topological domainCytoplasmic
TgeneTMX2chr11:57561553chr11:57505079ENST0000037831207126_29663259.0Topological domainCytoplasmic
TgeneTMX2chr11:57561553chr11:57505079ENST0000027842208103_12563297.0TransmembraneHelical
TgeneTMX2chr11:57561553chr11:57505079ENST0000037831207103_12563259.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCTNND1chr11:57561553chr11:57505079ENST00000415361+21910_460868.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000426142+21710_460833.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000525902+11510_460617.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526357+31910_4635909.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526772+11410_460611.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000527467+11610_460646.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528232+21810_460839.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528621+31810_4635880.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529526+41910_4635880.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529873+31810_4635888.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529986+21710_460833.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530094+21810_460862.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530748+31910_4635886.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000531014+11510_460640.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532245+11610_460833.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532463+21710_460833.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532649+41910_4635880.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532787+21710_460841.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532844+32010_4635915.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000533667+11410_460619.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000534579+41910_4635880.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND1chr11:57561553chr11:57505079ENST00000358694+419358_39589934.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000358694+419398_43789934.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000358694+419441_47589934.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000358694+419476_51689934.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000358694+419534_57389934.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000358694+419583_62489934.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000358694+419653_69389934.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000358694+419700_73989934.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000358694+419740_78089934.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000358694+419781_82689934.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000360682+420358_39589948.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000360682+420398_43789948.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000360682+420441_47589948.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000360682+420476_51689948.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000360682+420534_57389948.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000360682+420583_62489948.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000360682+420653_69389948.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000360682+420700_73989948.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000360682+420740_78089948.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000360682+420781_82689948.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361332+420358_39589963.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361332+420398_43789963.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361332+420441_47589963.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361332+420476_51689963.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361332+420534_57389963.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361332+420583_62489963.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361332+420653_69389963.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361332+420700_73989963.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361332+420740_78089963.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361332+420781_82689963.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361391+419358_39589942.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361391+419398_43789942.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361391+419441_47589942.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361391+419476_51689942.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361391+419534_57389942.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361391+419583_62489942.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361391+419653_69389942.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361391+419700_73989942.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361391+419740_78089942.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361391+419781_82689942.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361796+419358_39589934.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361796+419398_43789934.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361796+419441_47589934.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361796+419476_51689934.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361796+419534_57389934.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361796+419583_62489934.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361796+419653_69389934.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361796+419700_73989934.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361796+419740_78089934.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000361796+419781_82689934.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000399050+421358_39589969.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000399050+421398_43789969.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000399050+421441_47589969.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000399050+421476_51689969.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000399050+421534_57389969.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000399050+421583_62489969.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000399050+421653_69389969.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000399050+421700_73989969.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000399050+421740_78089969.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000399050+421781_82689969.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000415361+219358_3950868.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000415361+219398_4370868.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000415361+219441_4750868.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000415361+219476_5160868.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000415361+219534_5730868.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000415361+219583_6240868.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000415361+219653_6930868.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000415361+219700_7390868.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000415361+219740_7800868.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000415361+219781_8260868.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000426142+217358_3950833.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000426142+217398_4370833.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000426142+217441_4750833.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000426142+217476_5160833.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000426142+217534_5730833.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000426142+217583_6240833.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000426142+217653_6930833.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000426142+217700_7390833.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000426142+217740_7800833.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000426142+217781_8260833.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000428599+318358_39589934.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000428599+318398_43789934.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000428599+318441_47589934.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000428599+318476_51689934.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000428599+318534_57389934.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000428599+318583_62489934.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000428599+318653_69389934.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000428599+318700_73989934.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000428599+318740_78089934.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000428599+318781_82689934.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000524630+419358_39589934.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000524630+419398_43789934.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000524630+419441_47589934.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000524630+419476_51689934.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000524630+419534_57389934.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000524630+419583_62489934.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000524630+419653_69389934.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000524630+419700_73989934.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000524630+419740_78089934.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000524630+419781_82689934.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000525902+115358_3950617.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000525902+115398_4370617.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000525902+115441_4750617.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000525902+115476_5160617.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000525902+115534_5730617.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000525902+115583_6240617.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000525902+115653_6930617.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000525902+115700_7390617.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000525902+115740_7800617.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000525902+115781_8260617.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526357+319358_39535909.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526357+319398_43735909.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526357+319441_47535909.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526357+319476_51635909.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526357+319534_57335909.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526357+319583_62435909.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526357+319653_69335909.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526357+319700_73935909.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526357+319740_78035909.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526357+319781_82635909.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526772+114358_3950611.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526772+114398_4370611.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526772+114441_4750611.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526772+114476_5160611.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526772+114534_5730611.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526772+114583_6240611.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526772+114653_6930611.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526772+114700_7390611.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526772+114740_7800611.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526772+114781_8260611.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526938+318358_39589919.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526938+318398_43789919.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526938+318441_47589919.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526938+318476_51689919.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526938+318534_57389919.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526938+318583_62489919.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526938+318653_69389919.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526938+318700_73989919.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526938+318740_78089919.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000526938+318781_82689919.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000527467+116358_3950646.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000527467+116398_4370646.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000527467+116441_4750646.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000527467+116476_5160646.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000527467+116534_5730646.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000527467+116583_6240646.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000527467+116653_6930646.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000527467+116700_7390646.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000527467+116740_7800646.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000527467+116781_8260646.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528232+218358_3950839.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528232+218398_4370839.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528232+218441_4750839.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528232+218476_5160839.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528232+218534_5730839.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528232+218583_6240839.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528232+218653_6930839.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528232+218700_7390839.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528232+218740_7800839.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528232+218781_8260839.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528621+318358_39535880.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528621+318398_43735880.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528621+318441_47535880.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528621+318476_51635880.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528621+318534_57335880.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528621+318583_62435880.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528621+318653_69335880.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528621+318700_73935880.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528621+318740_78035880.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000528621+318781_82635880.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529526+419358_39535880.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529526+419398_43735880.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529526+419441_47535880.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529526+419476_51635880.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529526+419534_57335880.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529526+419583_62435880.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529526+419653_69335880.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529526+419700_73935880.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529526+419740_78035880.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529526+419781_82635880.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529873+318358_39535888.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529873+318398_43735888.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529873+318441_47535888.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529873+318476_51635888.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529873+318534_57335888.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529873+318583_62435888.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529873+318653_69335888.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529873+318700_73935888.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529873+318740_78035888.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529873+318781_82635888.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529986+217358_3950833.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529986+217398_4370833.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529986+217441_4750833.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529986+217476_5160833.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529986+217534_5730833.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529986+217583_6240833.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529986+217653_6930833.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529986+217700_7390833.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529986+217740_7800833.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000529986+217781_8260833.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530094+218358_3950862.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530094+218398_4370862.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530094+218441_4750862.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530094+218476_5160862.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530094+218534_5730862.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530094+218583_6240862.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530094+218653_6930862.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530094+218700_7390862.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530094+218740_7800862.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530094+218781_8260862.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530748+319358_39535886.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530748+319398_43735886.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530748+319441_47535886.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530748+319476_51635886.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530748+319534_57335886.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530748+319583_62435886.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530748+319653_69335886.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530748+319700_73935886.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530748+319740_78035886.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000530748+319781_82635886.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000531014+115358_3950640.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000531014+115398_4370640.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000531014+115441_4750640.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000531014+115476_5160640.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000531014+115534_5730640.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000531014+115583_6240640.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000531014+115653_6930640.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000531014+115700_7390640.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000531014+115740_7800640.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000531014+115781_8260640.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532245+116358_3950833.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532245+116398_4370833.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532245+116441_4750833.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532245+116476_5160833.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532245+116534_5730833.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532245+116583_6240833.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532245+116653_6930833.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532245+116700_7390833.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532245+116740_7800833.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532245+116781_8260833.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532463+217358_3950833.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532463+217398_4370833.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532463+217441_4750833.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532463+217476_5160833.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532463+217534_5730833.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532463+217583_6240833.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532463+217653_6930833.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532463+217700_7390833.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532463+217740_7800833.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532463+217781_8260833.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532649+419358_39535880.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532649+419398_43735880.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532649+419441_47535880.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532649+419476_51635880.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532649+419534_57335880.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532649+419583_62435880.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532649+419653_69335880.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532649+419700_73935880.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532649+419740_78035880.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532649+419781_82635880.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532787+217358_3950841.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532787+217398_4370841.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532787+217441_4750841.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532787+217476_5160841.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532787+217534_5730841.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532787+217583_6240841.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532787+217653_6930841.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532787+217700_7390841.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532787+217740_7800841.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532787+217781_8260841.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532844+320358_39535915.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532844+320398_43735915.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532844+320441_47535915.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532844+320476_51635915.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532844+320534_57335915.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532844+320583_62435915.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532844+320653_69335915.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532844+320700_73935915.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532844+320740_78035915.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000532844+320781_82635915.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000533667+114358_3950619.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000533667+114398_4370619.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000533667+114441_4750619.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000533667+114476_5160619.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000533667+114534_5730619.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000533667+114583_6240619.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000533667+114653_6930619.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000533667+114700_7390619.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000533667+114740_7800619.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000533667+114781_8260619.0RepeatNote=ARM 10
HgeneCTNND1chr11:57561553chr11:57505079ENST00000534579+419358_39535880.0RepeatNote=ARM 1
HgeneCTNND1chr11:57561553chr11:57505079ENST00000534579+419398_43735880.0RepeatNote=ARM 2
HgeneCTNND1chr11:57561553chr11:57505079ENST00000534579+419441_47535880.0RepeatNote=ARM 3
HgeneCTNND1chr11:57561553chr11:57505079ENST00000534579+419476_51635880.0RepeatNote=ARM 4
HgeneCTNND1chr11:57561553chr11:57505079ENST00000534579+419534_57335880.0RepeatNote=ARM 5
HgeneCTNND1chr11:57561553chr11:57505079ENST00000534579+419583_62435880.0RepeatNote=ARM 6
HgeneCTNND1chr11:57561553chr11:57505079ENST00000534579+419653_69335880.0RepeatNote=ARM 7
HgeneCTNND1chr11:57561553chr11:57505079ENST00000534579+419700_73935880.0RepeatNote=ARM 8
HgeneCTNND1chr11:57561553chr11:57505079ENST00000534579+419740_78035880.0RepeatNote=ARM 9
HgeneCTNND1chr11:57561553chr11:57505079ENST00000534579+419781_82635880.0RepeatNote=ARM 10
TgeneTMX2chr11:57561553chr11:57505079ENST000002784220849_10263297.0Topological domainExtracellular
TgeneTMX2chr11:57561553chr11:57505079ENST000003783120749_10263259.0Topological domainExtracellular


Top

Fusion Gene Sequence for CTNND1-TMX2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

Top

Fusion Gene PPI Analysis for CTNND1-TMX2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for CTNND1-TMX2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for CTNND1-TMX2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCTNND1C0008925Cleft Palate1GENOMICS_ENGLAND
HgeneCTNND1C1861536Blepharo-cheilo-dontic syndrome1ORPHANET
TgeneC0025958Microcephaly1GENOMICS_ENGLAND
TgeneC0036572Seizures1GENOMICS_ENGLAND
TgeneC0557874Global developmental delay1GENOMICS_ENGLAND
TgeneC1856019Abnormal cortical gyration1GENOMICS_ENGLAND
TgeneC3714756Intellectual Disability1GENOMICS_ENGLAND