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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CTNND2-PPARGC1B (FusionGDB2 ID:HG1501TG133522)

Fusion Gene Summary for CTNND2-PPARGC1B

check button Fusion gene summary
Fusion gene informationFusion gene name: CTNND2-PPARGC1B
Fusion gene ID: hg1501tg133522
HgeneTgene
Gene symbol

CTNND2

PPARGC1B

Gene ID

1501

133522

Gene namecatenin delta 2PPARG coactivator 1 beta
SynonymsGT24|NPRAPERRL1|PERC|PGC-1(beta)|PGC1B
Cytomap('CTNND2')('PPARGC1B')

5p15.2

5q32

Type of geneprotein-codingprotein-coding
Descriptioncatenin delta-2T-cell delta-catenincatenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)neurojunginperoxisome proliferator-activated receptor gamma coactivator 1-betaPGC-1-related estrogen receptor alpha coactivatorPPAR-gamma coactivator 1-betaPPARGC-1-betaPPARgamma coactivator 1 betaperoxisome proliferator-activated receptor gamma, coactivator 1
Modification date2020032020200322
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000304623, ENST00000359640, 
ENST00000458100, ENST00000503622, 
ENST00000511377, ENST00000495388, 
Fusion gene scores* DoF score14 X 13 X 7=12748 X 7 X 7=392
# samples 159
** MAII scorelog2(15/1274*10)=-3.08633087176042
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/392*10)=-2.12285674778553
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CTNND2 [Title/Abstract] AND PPARGC1B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCTNND2(11082808)-PPARGC1B(149199996), # samples:1
Anticipated loss of major functional domain due to fusion event.CTNND2-PPARGC1B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CTNND2-PPARGC1B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CTNND2-PPARGC1B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CTNND2-PPARGC1B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CTNND2-PPARGC1B seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
CTNND2-PPARGC1B seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CTNND2-PPARGC1B seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
CTNND2-PPARGC1B seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePPARGC1B

GO:0006355

regulation of transcription, DNA-templated

23836911

TgenePPARGC1B

GO:0030520

intracellular estrogen receptor signaling pathway

11854298

TgenePPARGC1B

GO:0045944

positive regulation of transcription by RNA polymerase II

11854298


check buttonFusion gene breakpoints across CTNND2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across PPARGC1B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-D3-A51N-06ACTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+


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Fusion Gene ORF analysis for CTNND2-PPARGC1B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000304623ENST00000309241CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5CDS-intronENST00000304623ENST00000403750CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5CDS-intronENST00000304623ENST00000461780CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5CDS-intronENST00000359640ENST00000309241CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5CDS-intronENST00000359640ENST00000403750CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5CDS-intronENST00000359640ENST00000461780CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5CDS-intronENST00000458100ENST00000309241CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5CDS-intronENST00000458100ENST00000403750CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5CDS-intronENST00000458100ENST00000461780CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5CDS-intronENST00000503622ENST00000309241CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5CDS-intronENST00000503622ENST00000403750CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5CDS-intronENST00000503622ENST00000461780CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5CDS-intronENST00000511377ENST00000309241CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5CDS-intronENST00000511377ENST00000403750CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5CDS-intronENST00000511377ENST00000461780CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5UTR-3CDSENST00000495388ENST00000360453CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5UTR-3CDSENST00000495388ENST00000394320CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5UTR-intronENST00000495388ENST00000309241CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5UTR-intronENST00000495388ENST00000403750CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
5UTR-intronENST00000495388ENST00000461780CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
Frame-shiftENST00000304623ENST00000360453CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
Frame-shiftENST00000304623ENST00000394320CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
Frame-shiftENST00000359640ENST00000360453CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
Frame-shiftENST00000359640ENST00000394320CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
In-frameENST00000458100ENST00000360453CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
In-frameENST00000458100ENST00000394320CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
In-frameENST00000503622ENST00000360453CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
In-frameENST00000503622ENST00000394320CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
In-frameENST00000511377ENST00000360453CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+
In-frameENST00000511377ENST00000394320CTNND2chr5

11082808

-PPARGC1Bchr5

149199996

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000511377CTNND2chr511082808-ENST00000360453PPARGC1Bchr5149199996+5769288828135764983
ENST00000511377CTNND2chr511082808-ENST00000394320PPARGC1Bchr5149199996+75712888281358631016
ENST00000458100CTNND2chr511082808-ENST00000360453PPARGC1Bchr5149199996+5294241323385289983
ENST00000458100CTNND2chr511082808-ENST00000394320PPARGC1Bchr5149199996+70962413233853881016
ENST00000503622CTNND2chr511082808-ENST00000360453PPARGC1Bchr5149199996+4860197919044855983
ENST00000503622CTNND2chr511082808-ENST00000394320PPARGC1Bchr5149199996+66621979190449541016

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000511377ENST00000360453CTNND2chr511082808-PPARGC1Bchr5149199996+0.0572946850.94270533
ENST00000511377ENST00000394320CTNND2chr511082808-PPARGC1Bchr5149199996+0.0578713750.94212866
ENST00000458100ENST00000360453CTNND2chr511082808-PPARGC1Bchr5149199996+0.0482220240.95177794
ENST00000458100ENST00000394320CTNND2chr511082808-PPARGC1Bchr5149199996+0.0439386220.9560614
ENST00000503622ENST00000360453CTNND2chr511082808-PPARGC1Bchr5149199996+0.0356656570.9643343
ENST00000503622ENST00000394320CTNND2chr511082808-PPARGC1Bchr5149199996+0.0294519160.97054803

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Fusion Genomic Features for CTNND2-PPARGC1B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CTNND2chr511082807-PPARGC1Bchr5149199995+6.26E-060.9999937
CTNND2chr511082807-PPARGC1Bchr5149199995+6.26E-060.9999937

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CTNND2-PPARGC1B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:11082808/chr5:149199996)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCTNND2chr5:11082808chr5:149199996ENST00000304623-162249_849291226.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND2chr5:11082808chr5:149199996ENST00000359640-152149_848711168.0Coiled coilOntology_term=ECO:0000255
HgeneCTNND2chr5:11082808chr5:149199996ENST00000304623-1622216_2269291226.0Compositional biasNote=Poly-Pro
HgeneCTNND2chr5:11082808chr5:149199996ENST00000304623-1622811_8179291226.0Compositional biasNote=Poly-Lys
HgeneCTNND2chr5:11082808chr5:149199996ENST00000359640-1521216_2268711168.0Compositional biasNote=Poly-Pro
HgeneCTNND2chr5:11082808chr5:149199996ENST00000359640-1521811_8178711168.0Compositional biasNote=Poly-Lys
HgeneCTNND2chr5:11082808chr5:149199996ENST00000304623-1622394_4389291226.0RepeatNote=ARM 1
HgeneCTNND2chr5:11082808chr5:149199996ENST00000304623-1622540_5799291226.0RepeatNote=ARM 2
HgeneCTNND2chr5:11082808chr5:149199996ENST00000304623-1622582_6219291226.0RepeatNote=ARM 3
HgeneCTNND2chr5:11082808chr5:149199996ENST00000304623-1622626_6669291226.0RepeatNote=ARM 4
HgeneCTNND2chr5:11082808chr5:149199996ENST00000304623-1622682_7249291226.0RepeatNote=ARM 5
HgeneCTNND2chr5:11082808chr5:149199996ENST00000304623-1622728_7739291226.0RepeatNote=ARM 6
HgeneCTNND2chr5:11082808chr5:149199996ENST00000304623-1622835_8759291226.0RepeatNote=ARM 7
HgeneCTNND2chr5:11082808chr5:149199996ENST00000304623-1622882_9219291226.0RepeatNote=ARM 8
HgeneCTNND2chr5:11082808chr5:149199996ENST00000359640-1521394_4388711168.0RepeatNote=ARM 1
HgeneCTNND2chr5:11082808chr5:149199996ENST00000359640-1521540_5798711168.0RepeatNote=ARM 2
HgeneCTNND2chr5:11082808chr5:149199996ENST00000359640-1521582_6218711168.0RepeatNote=ARM 3
HgeneCTNND2chr5:11082808chr5:149199996ENST00000359640-1521626_6668711168.0RepeatNote=ARM 4
HgeneCTNND2chr5:11082808chr5:149199996ENST00000359640-1521682_7248711168.0RepeatNote=ARM 5
HgeneCTNND2chr5:11082808chr5:149199996ENST00000359640-1521728_7738711168.0RepeatNote=ARM 6
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000309241012430_450261024.0Compositional biasNote=Glu-rich
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000309241012772_823261024.0Compositional biasNote=Glu-rich
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000360453011430_45026985.0Compositional biasNote=Glu-rich
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000360453011772_82326985.0Compositional biasNote=Glu-rich
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000394320011430_450261018.0Compositional biasNote=Glu-rich
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000394320011772_823261018.0Compositional biasNote=Glu-rich
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000403750011430_4501960.0Compositional biasNote=Glu-rich
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000403750011772_8231960.0Compositional biasNote=Glu-rich
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000309241012902_976261024.0DomainRRM
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000360453011902_97626985.0DomainRRM
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000394320011902_976261018.0DomainRRM
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000403750011902_9761960.0DomainRRM
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000309241012156_160261024.0MotifNote=LXXLL motif 1
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000309241012691_694261024.0MotifNote=HCFC1-binding-motif (HBM)
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000360453011156_16026985.0MotifNote=LXXLL motif 1
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000360453011691_69426985.0MotifNote=HCFC1-binding-motif (HBM)
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000394320011156_160261018.0MotifNote=LXXLL motif 1
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000394320011691_694261018.0MotifNote=HCFC1-binding-motif (HBM)
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000403750011156_1601960.0MotifNote=LXXLL motif 1
TgenePPARGC1Bchr5:11082808chr5:149199996ENST00000403750011691_6941960.0MotifNote=HCFC1-binding-motif (HBM)
TgenePPARGC1Bchr5:11082808chr5:149199996ENST000004037500111_911960.0RegionNote=Abolishes DNA transcriptional activity when missing

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCTNND2chr5:11082808chr5:149199996ENST00000304623-1622975_10189291226.0RepeatNote=ARM 9
HgeneCTNND2chr5:11082808chr5:149199996ENST00000359640-1521835_8758711168.0RepeatNote=ARM 7
HgeneCTNND2chr5:11082808chr5:149199996ENST00000359640-1521882_9218711168.0RepeatNote=ARM 8
HgeneCTNND2chr5:11082808chr5:149199996ENST00000359640-1521975_10188711168.0RepeatNote=ARM 9
TgenePPARGC1Bchr5:11082808chr5:149199996ENST000003092410121_91261024.0RegionNote=Abolishes DNA transcriptional activity when missing
TgenePPARGC1Bchr5:11082808chr5:149199996ENST000003604530111_9126985.0RegionNote=Abolishes DNA transcriptional activity when missing
TgenePPARGC1Bchr5:11082808chr5:149199996ENST000003943200111_91261018.0RegionNote=Abolishes DNA transcriptional activity when missing


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Fusion Gene Sequence for CTNND2-PPARGC1B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>20399_20399_1_CTNND2-PPARGC1B_CTNND2_chr5_11082808_ENST00000458100_PPARGC1B_chr5_149199996_ENST00000360453_length(transcript)=5294nt_BP=2413nt
GCGTCGGGAGCCGCCTCTCGCCCGCGGCGCTCGCCCCTGCCGCCCGCCAGCATCCCTTGTCCCGCGGCCGCGCTCAGACAACAAAAGCGG
AAGATGCTGCAGTTGGGCAAGGTCAGGACCTTGCCCTGAAGCCGGGCGGCGCCGCGCACGCCTCTTCCCGGACTGAGGAGCTGTCGCCGG
CGGAGGGTGCATGTTTGCGAGGAAGCCGCCGGGCGCCGCGCCTTTGGGAGCTATGCCTGTTCCAGACCAGCCTTCATCAGCCTCAGAGAA
GACGAGTTCCCTGAGCCCCGGCTTAAACACCTCCAACGGGGATGGCTCTGAAACAGAAACCACCTCTGCCATCCTCGCCTCAGTCAAAGA
ACAGGAATTACAGTTTGAAAGGCTGACCCGAGAGCTGGAGGCTGAACGGCAGATCGTAGCCAGCCAGCTGGAGCGATGCAAGCTCGGATC
CGAGACTGGCAGCATGAGCAGCATGAGTTCAGCAGAAGAGCAGTTTCAGTGGCAGTCACAAGATGGTCAAAAAGATATCGAAGATGAGCT
TACAACAGGTCTCGAGCTGGTGGACTCCTGTATTAGGTCACTACAGGAATCAGGAATACTTGACCCACAGGATTATTCTACAGGTGAAAG
GCCCAGCCTGCTCTCCCAGAGTGCACTTCAGCTCAATTCCAAACCTGAAGGGTCTTTCCAGTATCCGGCCAGCTACCATAGCAACCAGAC
CCTGGCCCTGGGGGAAACCACCCCTTCACAGCTCCCGGCCCGAGGCACACAAGCCCGAGCTACGGGCCAGAGCTTCAGCCAGCTGGTTCC
CGAGCCTCATACAGCAGCCAGCATGGGCACCTGGGCCCAGAGTTGCGGGCCCTGCAGTCCCCAGAACACCACATAGATCCCATCTATGAA
GACCGCGTCTATCAGAAGCCCCCTATGAGGAGTCTCAGCCAGAGCCAGGGGGACCCTCTGCCGCCAGCACACACCGGCACCTACCGCACG
AGCACAGCCCCATCTTCCCCTGGTGTCGACTCCGTCCCCTTGCAGCGCACAGGCAGCCAGCACGGCCCACAGAATGCCGCCGCGGCCACC
TTCCAGAGGGCCAGCTATGCCGCCGGCCCAGCCTCCAATTACGCGGACCCCTACCGACAGCTGCAGTATTGTCCCTCTGTTGAGTCTCCA
TACAGCAAATCCGGCCCTGCTCTCCCGCCTGAAGGCACCTTGGCCAGGTCCCCGTCCATTGATAGCATTCAGAAAGATCCCAGAGAATTT
GGATGGAGAGACCCGGAACTGCCGGAAGTGATTCAGATGTTGCAGCACCAGTTTCCCTCGGTCCAGTCTAACGCGGCAGCCTACTTGCAA
CACCTCTGTTTTGGAGACAACAAAATTAAAGCCGAGATAAGGAGACAAGGAGGCATCCAGCTCCTGGTGGACCTGTTGGATCATCGGATG
ACCGAAGTCCACCGTAGTGCCTGTGGAGCTCTGAGAAACCTGGTGTATGGGAAGGCCAACGATGATAACAAAATTGCCCTGAAAAACTGT
GGTGGCATCCCAGCACTGGTGAGGTTACTCCGCAAGACGACTGACCTGGAGATCCGGGAGCTGGTCACAGGAGTCCTTTGGAACCTCTCC
TCATGCGATGCACTCAAAATGCCAATCATCCAGGATGCCCTAGCAGTACTGACCAACGCGGTGATTATCCCCCACTCAGGCTGGGAAAAT
TCGCCTCTTCAGGATGATCGGAAAATACAGCTGCATTCATCACAGGTGCTGCGTAACGCCACCGGGTGCCTAAGGAATGTTAGTTCGGCC
GGAGAGGAGGCCCGCAGAAGGATGAGAGAGTGTGATGGGCTTACGGATGCCTTGCTGTACGTGATCCAGTCTGCGCTGGGGAGCAGTGAG
ATCGATAGCAAGACCGTTGAAAACTGTGTGTGCATTTTAAGGAACCTCTCGTACCGGCTGGCGGCAGAAACGTCTCAGGGACAGCACATG
GGCACGGACGAGCTGGACGGGCTACTCTGTGGCGAGGCCAATGGCAAGGATGCTGAGAGCTCTGGGTGCTGGGGCAAGAAGAAGAAGAAA
AAGAAATCCCAAGATCAGTGGGATGGAGTAGGACCTCTTCCAGACTGTGCTGAACCACCAAAAGGGATCCAGATGCTGTGGCACCCATCA
ATAGTCAAACCCTACCTCACACTGCTCTCTGAGTGCTCAAATCCAGACACGCTGGAAGGGGCGGCAGGCGCCCTGCAGAACTTGGCTGCA
GGGAGCTGGAAGTGGTCAGTATATATCCGAGCCGCTGTCCGAAAAGAGAAAGGCCTGCCCATCCTCGTGGAGCTGCTCCGAATAGACAAT
GACCGTGTGGTGTGCGCGGTGGCCACTGCGCTGCGGAACATGGCCTTGGACGTCAGAAATAAGGAGCTCATCGGGTGGAGGGTCCGGGGA
GGAGCAACTCTATGCTGACTTTCCAGAACTTGACCTCTCCCAGCTGGATGCCAGCGACTTTGACTCGGCCACCTGCTTTGGGGAGCTGCA
GTGGTGCCCAGAGAACTCAGAGACTGAACCCAACCAGTACAGCCCCGATGACTCCGAGCTCTTCCAGATTGACAGTGAGAATGAGGCCCT
CCTGGCAGAGCTCACCAAGACCCTGGATGACATCCCTGAAGATGACGTGGGTCTGGCTGCCTTCCCAGCCCTGGATGGTGGAGACGCTCT
ATCATGCACCTCAGCTTCGCCTGCCCCCTCATCTGCACCCCCCAGCCCTGCCCCGGAGAAGCCCTCGGCCCCAGCCCCTGAGGTGGACGA
GCTCTCACTGGCGGACAGCACCCAAGACAAGAAGGCTCCCATGATGCAGTCTCAGAGCCGAAGTTGTACAGAACTACATAAGCACCTCAC
CTCGGCACAGTGCTGCCTGCAGGATCGGGGTCTGCAGCCACCATGCCTCCAGAGTCCCCGGCTCCCTGCCAAGGAGGACAAGGAGCCGGG
TGAGGACTGCCCGAGCCCCCAGCCAGCTCCAGCCTCTCCCCGGGACTCCCTAGCTCTGGGCAGGGCAGACCCCGGTGCCCCGGTTTCCCA
GGAAGACATGCAGGCGATGGTGCAACTCATACGCTACATGCACACCTACTGCCTCCCCCAGAGGAAGCTGCCCCCACAGACCCCTGAGCC
ACTCCCCAAGGCCTGCAGCAACCCCTCCCAGCAGGTCAGATCCCGGCCCTGGTCCCGGCACCACTCCAAAGCCTCCTGGGCTGAGTTCTC
CATTCTGAGGGAACTTCTGGCTCAAGACGTGCTCTGTGATGTCAGCAAACCCTACCGTCTGGCCACGCCTGTTTATGCCTCCCTCACACC
TCGGTCAAGGCCCAGGCCCCCCAAAGACAGTCAGGCCTCCCCTGGTCGCCCGTCCTCGGTGGAGGAGGTAAGGATCGCAGCTTCACCCAA
GAGCACCGGGCCCAGACCAAGCCTGCGCCCACTGCGGCTGGAGGTGAAAAGGGAGGTCCGCCGGCCTGCCAGACTGCAGCAGCAGGAGGA
GGAAGACGAGGAAGAAGAGGAGGAGGAAGAGGAAGAAGAAAAAGAGGAGGAGGAGGAGTGGGGCAGGAAAAGGCCAGGCCGAGGCCTGCC
ATGGACGAAGCTGGGGAGGAAGCTGGAGAGCTCTGTGTGCCCCGTGCGGCGTTCTCGGAGACTGAACCCTGAGCTGGGCCCCTGGCTGAC
ATTTGCAGATGAGCCGCTGGTCCCCTCGGAGCCCCAAGGTGCTCTGCCCTCACTGTGCCTGGCTCCCAAGGCCTACGACGTAGAGCGGGA
GCTGGGCAGCCCCACGGACGAGGACAGTGGCCAAGACCAGCAGCTCCTACGGGGACCCCAGATCCCTGCCCTGGAGAGCCCCTGTGAGAG
TGGGTGTGGGGACATGGATGAGGACCCCAGCTGCCCGCAGCTCCCTCCCAGAGACTCTCCCAGGTGCCTCATGCTGGCCTTGTCACAAAG
CGACCCAACTTTTGGCAAGAAGAGCTTTGAGCAGACCTTGACAGTGGAGCTCTGTGGCACAGCAGGACTCACCCCACCCACCACACCACC
GTACAAGCCCACAGAGGAGGATCCCTTCAAACCAGACATCAAGCATAGTCTAGGCAAAGAAATAGCTCTCAGCCTCCCCTCCCCTGAGGG
CCTCTCACTCAAGGCCACCCCAGGGGCTGCCCACAAGCTGCCAAAGAAGCACCCAGAGCGAAGTGAGCTCCTGTCCCACCTGCGACATGC
CACAGCCCAGCCAGCCTCCCAGGCTGGCCAGAAGCGTCCCTTCTCCTGTTCCTTTGGAGACCATGACTACTGCCAGGTGCTCCGACCAGA
AGGCGTCCTGCAAAGGAAGGTGCTGAGGTCCTGGGAGCCGTCTGGGGTTCACCTTGAGGACTGGCCCCAGCAGGGTGCCCCTTGGGCTGA
GGCACAGGCCCCTGGCAGGGAGGAAGACAGAAGCTGTGATGCTGGCGCCCCACCCAAGGACAGCACGCTGCTGAGAGACCATGAGATCCG
TGCCAGCCTCACCAAACACTTTGGGCTGCTGGAGACCGCCCTGGAGGAGGAAGACCTGGCCTCCTGCAAGAGCCCTGAGTATGACACTGT
CTTTGAAGACAGCAGCAGCAGCAGCGGCGAGAGCAGCTTCCTCCCAGAGGAGGAAGAGGAAGAAGGGGAGGAGGAGGAGGAGGACGATGA
AGAAGAGGACTCAGGGGTCAGCCCCACTTGCTCTGACCACTGCCCCTACCAGAGCCCACCAAGCAAGGCCAACCGGCAGCTCTGTTCCCG
CAGCCGCTCAAGCTCTGGCTCTTCACCCTGCCACTCCTGGTCACCAGCCACTCGAAGGAACTTCAGATGTGAGAGCAGAGGGCCGTGTTC
AGACAGAACGCCAAGCATCCGGCACGCCAGGAAGCGGCGGGAAAAGGCCATTGGGGAAGGCCGCGTGGTGTACATTCAAAATCTCTCCAG
CGACATGAGCTCCCGAGAGCTGAAGAGGCGCTTTGAAGTGTTTGGTGAGATTGAGGAGTGCGAGGTGCTGACAAGAAATAGGAGAGGCGA
GAAGTACGGCTTCATCACCTACCGGTGTTCTGAGCACGCGGCCCTCTCTTTGACAAAGGGCGCTGCCCTGAGGAAGCGCAACGAGCCCTC
CTTCCAGCTGAGCTACGGAGGGCTCCGGCACTTCTGCTGGCCCAGATACACTGACTACGATTCCAATTCAGAAGAGGCCCTTCCTGCGTC

>20399_20399_1_CTNND2-PPARGC1B_CTNND2_chr5_11082808_ENST00000458100_PPARGC1B_chr5_149199996_ENST00000360453_length(amino acids)=983AA_BP=25
MTVWCARWPLRCGTWPWTSEIRSSSGGGSGEEQLYADFPELDLSQLDASDFDSATCFGELQWCPENSETEPNQYSPDDSELFQIDSENEA
LLAELTKTLDDIPEDDVGLAAFPALDGGDALSCTSASPAPSSAPPSPAPEKPSAPAPEVDELSLADSTQDKKAPMMQSQSRSCTELHKHL
TSAQCCLQDRGLQPPCLQSPRLPAKEDKEPGEDCPSPQPAPASPRDSLALGRADPGAPVSQEDMQAMVQLIRYMHTYCLPQRKLPPQTPE
PLPKACSNPSQQVRSRPWSRHHSKASWAEFSILRELLAQDVLCDVSKPYRLATPVYASLTPRSRPRPPKDSQASPGRPSSVEEVRIAASP
KSTGPRPSLRPLRLEVKREVRRPARLQQQEEEDEEEEEEEEEEEKEEEEEWGRKRPGRGLPWTKLGRKLESSVCPVRRSRRLNPELGPWL
TFADEPLVPSEPQGALPSLCLAPKAYDVERELGSPTDEDSGQDQQLLRGPQIPALESPCESGCGDMDEDPSCPQLPPRDSPRCLMLALSQ
SDPTFGKKSFEQTLTVELCGTAGLTPPTTPPYKPTEEDPFKPDIKHSLGKEIALSLPSPEGLSLKATPGAAHKLPKKHPERSELLSHLRH
ATAQPASQAGQKRPFSCSFGDHDYCQVLRPEGVLQRKVLRSWEPSGVHLEDWPQQGAPWAEAQAPGREEDRSCDAGAPPKDSTLLRDHEI
RASLTKHFGLLETALEEEDLASCKSPEYDTVFEDSSSSSGESSFLPEEEEEEGEEEEEDDEEEDSGVSPTCSDHCPYQSPPSKANRQLCS
RSRSSSGSSPCHSWSPATRRNFRCESRGPCSDRTPSIRHARKRREKAIGEGRVVYIQNLSSDMSSRELKRRFEVFGEIEECEVLTRNRRG

--------------------------------------------------------------
>20399_20399_2_CTNND2-PPARGC1B_CTNND2_chr5_11082808_ENST00000458100_PPARGC1B_chr5_149199996_ENST00000394320_length(transcript)=7096nt_BP=2413nt
GCGTCGGGAGCCGCCTCTCGCCCGCGGCGCTCGCCCCTGCCGCCCGCCAGCATCCCTTGTCCCGCGGCCGCGCTCAGACAACAAAAGCGG
AAGATGCTGCAGTTGGGCAAGGTCAGGACCTTGCCCTGAAGCCGGGCGGCGCCGCGCACGCCTCTTCCCGGACTGAGGAGCTGTCGCCGG
CGGAGGGTGCATGTTTGCGAGGAAGCCGCCGGGCGCCGCGCCTTTGGGAGCTATGCCTGTTCCAGACCAGCCTTCATCAGCCTCAGAGAA
GACGAGTTCCCTGAGCCCCGGCTTAAACACCTCCAACGGGGATGGCTCTGAAACAGAAACCACCTCTGCCATCCTCGCCTCAGTCAAAGA
ACAGGAATTACAGTTTGAAAGGCTGACCCGAGAGCTGGAGGCTGAACGGCAGATCGTAGCCAGCCAGCTGGAGCGATGCAAGCTCGGATC
CGAGACTGGCAGCATGAGCAGCATGAGTTCAGCAGAAGAGCAGTTTCAGTGGCAGTCACAAGATGGTCAAAAAGATATCGAAGATGAGCT
TACAACAGGTCTCGAGCTGGTGGACTCCTGTATTAGGTCACTACAGGAATCAGGAATACTTGACCCACAGGATTATTCTACAGGTGAAAG
GCCCAGCCTGCTCTCCCAGAGTGCACTTCAGCTCAATTCCAAACCTGAAGGGTCTTTCCAGTATCCGGCCAGCTACCATAGCAACCAGAC
CCTGGCCCTGGGGGAAACCACCCCTTCACAGCTCCCGGCCCGAGGCACACAAGCCCGAGCTACGGGCCAGAGCTTCAGCCAGCTGGTTCC
CGAGCCTCATACAGCAGCCAGCATGGGCACCTGGGCCCAGAGTTGCGGGCCCTGCAGTCCCCAGAACACCACATAGATCCCATCTATGAA
GACCGCGTCTATCAGAAGCCCCCTATGAGGAGTCTCAGCCAGAGCCAGGGGGACCCTCTGCCGCCAGCACACACCGGCACCTACCGCACG
AGCACAGCCCCATCTTCCCCTGGTGTCGACTCCGTCCCCTTGCAGCGCACAGGCAGCCAGCACGGCCCACAGAATGCCGCCGCGGCCACC
TTCCAGAGGGCCAGCTATGCCGCCGGCCCAGCCTCCAATTACGCGGACCCCTACCGACAGCTGCAGTATTGTCCCTCTGTTGAGTCTCCA
TACAGCAAATCCGGCCCTGCTCTCCCGCCTGAAGGCACCTTGGCCAGGTCCCCGTCCATTGATAGCATTCAGAAAGATCCCAGAGAATTT
GGATGGAGAGACCCGGAACTGCCGGAAGTGATTCAGATGTTGCAGCACCAGTTTCCCTCGGTCCAGTCTAACGCGGCAGCCTACTTGCAA
CACCTCTGTTTTGGAGACAACAAAATTAAAGCCGAGATAAGGAGACAAGGAGGCATCCAGCTCCTGGTGGACCTGTTGGATCATCGGATG
ACCGAAGTCCACCGTAGTGCCTGTGGAGCTCTGAGAAACCTGGTGTATGGGAAGGCCAACGATGATAACAAAATTGCCCTGAAAAACTGT
GGTGGCATCCCAGCACTGGTGAGGTTACTCCGCAAGACGACTGACCTGGAGATCCGGGAGCTGGTCACAGGAGTCCTTTGGAACCTCTCC
TCATGCGATGCACTCAAAATGCCAATCATCCAGGATGCCCTAGCAGTACTGACCAACGCGGTGATTATCCCCCACTCAGGCTGGGAAAAT
TCGCCTCTTCAGGATGATCGGAAAATACAGCTGCATTCATCACAGGTGCTGCGTAACGCCACCGGGTGCCTAAGGAATGTTAGTTCGGCC
GGAGAGGAGGCCCGCAGAAGGATGAGAGAGTGTGATGGGCTTACGGATGCCTTGCTGTACGTGATCCAGTCTGCGCTGGGGAGCAGTGAG
ATCGATAGCAAGACCGTTGAAAACTGTGTGTGCATTTTAAGGAACCTCTCGTACCGGCTGGCGGCAGAAACGTCTCAGGGACAGCACATG
GGCACGGACGAGCTGGACGGGCTACTCTGTGGCGAGGCCAATGGCAAGGATGCTGAGAGCTCTGGGTGCTGGGGCAAGAAGAAGAAGAAA
AAGAAATCCCAAGATCAGTGGGATGGAGTAGGACCTCTTCCAGACTGTGCTGAACCACCAAAAGGGATCCAGATGCTGTGGCACCCATCA
ATAGTCAAACCCTACCTCACACTGCTCTCTGAGTGCTCAAATCCAGACACGCTGGAAGGGGCGGCAGGCGCCCTGCAGAACTTGGCTGCA
GGGAGCTGGAAGTGGTCAGTATATATCCGAGCCGCTGTCCGAAAAGAGAAAGGCCTGCCCATCCTCGTGGAGCTGCTCCGAATAGACAAT
GACCGTGTGGTGTGCGCGGTGGCCACTGCGCTGCGGAACATGGCCTTGGACGTCAGAAATAAGGAGCTCATCGGGTGGAGGGTCCGGGGA
GGAGCAACTCTATGCTGACTTTCCAGAACTTGACCTCTCCCAGCTGGATGCCAGCGACTTTGACTCGGCCACCTGCTTTGGGGAGCTGCA
GTGGTGCCCAGAGAACTCAGAGACTGAACCCAACCAGTACAGCCCCGATGACTCCGAGCTCTTCCAGATTGACAGTGAGAATGAGGCCCT
CCTGGCAGAGCTCACCAAGACCCTGGATGACATCCCTGAAGATGACGTGGGTCTGGCTGCCTTCCCAGCCCTGGATGGTGGAGACGCTCT
ATCATGCACCTCAGCTTCGCCTGCCCCCTCATCTGCACCCCCCAGCCCTGCCCCGGAGAAGCCCTCGGCCCCAGCCCCTGAGGTGGACGA
GCTCTCACTGCTGCAGAAGCTCCTCCTGGCCACATCCTACCCAACATCAAGCTCTGACACCCAGAAGGAAGGGACCGCCTGGCGCCAGGC
AGGCCTCAGATCTAAAAGTCAACGGCCTTGTGTTAAGGCGGACAGCACCCAAGACAAGAAGGCTCCCATGATGCAGTCTCAGAGCCGAAG
TTGTACAGAACTACATAAGCACCTCACCTCGGCACAGTGCTGCCTGCAGGATCGGGGTCTGCAGCCACCATGCCTCCAGAGTCCCCGGCT
CCCTGCCAAGGAGGACAAGGAGCCGGGTGAGGACTGCCCGAGCCCCCAGCCAGCTCCAGCCTCTCCCCGGGACTCCCTAGCTCTGGGCAG
GGCAGACCCCGGTGCCCCGGTTTCCCAGGAAGACATGCAGGCGATGGTGCAACTCATACGCTACATGCACACCTACTGCCTCCCCCAGAG
GAAGCTGCCCCCACAGACCCCTGAGCCACTCCCCAAGGCCTGCAGCAACCCCTCCCAGCAGGTCAGATCCCGGCCCTGGTCCCGGCACCA
CTCCAAAGCCTCCTGGGCTGAGTTCTCCATTCTGAGGGAACTTCTGGCTCAAGACGTGCTCTGTGATGTCAGCAAACCCTACCGTCTGGC
CACGCCTGTTTATGCCTCCCTCACACCTCGGTCAAGGCCCAGGCCCCCCAAAGACAGTCAGGCCTCCCCTGGTCGCCCGTCCTCGGTGGA
GGAGGTAAGGATCGCAGCTTCACCCAAGAGCACCGGGCCCAGACCAAGCCTGCGCCCACTGCGGCTGGAGGTGAAAAGGGAGGTCCGCCG
GCCTGCCAGACTGCAGCAGCAGGAGGAGGAAGACGAGGAAGAAGAGGAGGAGGAAGAGGAAGAAGAAAAAGAGGAGGAGGAGGAGTGGGG
CAGGAAAAGGCCAGGCCGAGGCCTGCCATGGACGAAGCTGGGGAGGAAGCTGGAGAGCTCTGTGTGCCCCGTGCGGCGTTCTCGGAGACT
GAACCCTGAGCTGGGCCCCTGGCTGACATTTGCAGATGAGCCGCTGGTCCCCTCGGAGCCCCAAGGTGCTCTGCCCTCACTGTGCCTGGC
TCCCAAGGCCTACGACGTAGAGCGGGAGCTGGGCAGCCCCACGGACGAGGACAGTGGCCAAGACCAGCAGCTCCTACGGGGACCCCAGAT
CCCTGCCCTGGAGAGCCCCTGTGAGAGTGGGTGTGGGGACATGGATGAGGACCCCAGCTGCCCGCAGCTCCCTCCCAGAGACTCTCCCAG
GTGCCTCATGCTGGCCTTGTCACAAAGCGACCCAACTTTTGGCAAGAAGAGCTTTGAGCAGACCTTGACAGTGGAGCTCTGTGGCACAGC
AGGACTCACCCCACCCACCACACCACCGTACAAGCCCACAGAGGAGGATCCCTTCAAACCAGACATCAAGCATAGTCTAGGCAAAGAAAT
AGCTCTCAGCCTCCCCTCCCCTGAGGGCCTCTCACTCAAGGCCACCCCAGGGGCTGCCCACAAGCTGCCAAAGAAGCACCCAGAGCGAAG
TGAGCTCCTGTCCCACCTGCGACATGCCACAGCCCAGCCAGCCTCCCAGGCTGGCCAGAAGCGTCCCTTCTCCTGTTCCTTTGGAGACCA
TGACTACTGCCAGGTGCTCCGACCAGAAGGCGTCCTGCAAAGGAAGGTGCTGAGGTCCTGGGAGCCGTCTGGGGTTCACCTTGAGGACTG
GCCCCAGCAGGGTGCCCCTTGGGCTGAGGCACAGGCCCCTGGCAGGGAGGAAGACAGAAGCTGTGATGCTGGCGCCCCACCCAAGGACAG
CACGCTGCTGAGAGACCATGAGATCCGTGCCAGCCTCACCAAACACTTTGGGCTGCTGGAGACCGCCCTGGAGGAGGAAGACCTGGCCTC
CTGCAAGAGCCCTGAGTATGACACTGTCTTTGAAGACAGCAGCAGCAGCAGCGGCGAGAGCAGCTTCCTCCCAGAGGAGGAAGAGGAAGA
AGGGGAGGAGGAGGAGGAGGACGATGAAGAAGAGGACTCAGGGGTCAGCCCCACTTGCTCTGACCACTGCCCCTACCAGAGCCCACCAAG
CAAGGCCAACCGGCAGCTCTGTTCCCGCAGCCGCTCAAGCTCTGGCTCTTCACCCTGCCACTCCTGGTCACCAGCCACTCGAAGGAACTT
CAGATGTGAGAGCAGAGGGCCGTGTTCAGACAGAACGCCAAGCATCCGGCACGCCAGGAAGCGGCGGGAAAAGGCCATTGGGGAAGGCCG
CGTGGTGTACATTCAAAATCTCTCCAGCGACATGAGCTCCCGAGAGCTGAAGAGGCGCTTTGAAGTGTTTGGTGAGATTGAGGAGTGCGA
GGTGCTGACAAGAAATAGGAGAGGCGAGAAGTACGGCTTCATCACCTACCGGTGTTCTGAGCACGCGGCCCTCTCTTTGACAAAGGGCGC
TGCCCTGAGGAAGCGCAACGAGCCCTCCTTCCAGCTGAGCTACGGAGGGCTCCGGCACTTCTGCTGGCCCAGATACACTGACTACGGTAA
GCCCCTGAAACCCAGCCACAGTCTAGTAAGACTCAAAGCTTGGGAAGCAGTGCCTTCCTTGAACAAAACCCAGAGCTAAAGCGCCTTGTG
GACATAGCTTCCATCCCCACACCCCAGTGTGCTGCTTGGTATAACTTTGCAGCCACTTTGCCTGAAGACTACCATCCTGTTTCTCTTCTG
GCCTCTGGTCCACCTTATCCTGTCCTGTGACTGCTACCAAAGAGAATCCAGCCTCCCACGGCCTCTAGGAAGATTCAGTCATGTGCACAG
CCAGCTGGCAGAACCGTGGCTACGGTCTCCTTGACTTCACAGGGCCAGCTGCTACCCTGTCCCCTTCAGGGGCATTCCGTGGTGACCCCA
GACAAGGCAGCAGCCACCTGGGGACAAGATGATGAAGAAGGACAAAGAAGTACAATGTACGAAAGAATTACTTGGCCAGGCTCAGTGGCT
CATGCCTGTAATCCCATCACCTTGGGAGGCTGAGGCAAGAGGATCACTTGAGCCCAGGAGTTCGAGACCAGCTTGGGCAACATAGTGAAA
TCCTGTCTCTACAAAAAATATAAAAATTAGCCAGGCATGGTGGCTTGCGCCTATAGTCCCAGCTACTCAGGAGGCAGAGGTGGGAGGATC
ACCTGAACCCAAGAGGTTGGAGCTGCAGTGAGCCATGATGGCACTACTGCATTCCAGCCTGGGCAACAGAGCAAGACCCTGTCTCAAAAG
GAAAGAAAAAAAAAAAAACACTTACTGGAGAGAATCCAATGCAGCCTTGATGGTACAGGACTGAGTGTCAGTGACCCGGCTGGGTGCCAG
GCCAGGCGGCCCTGCCCTTGGCTGCATGTCCATTTATGGGAATCAGTTTCCCAATCTATTAAAAAATTCTAGTGTTGGCTGGGTGCAGTT
GCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGAAGATCATGAGGTCAAGAGATCGAGACCATCGTGGCCAACATGGTGAA
ACCCCCTCTCTATTAAAAATACAAAAATTAGCTGGGCGTGGTGGCGCACACCTGTAGTCCCAGCAACTTGGGAGGCTGAGGCGGGAGAAT
CACTTGAACCCGAGAGGCAGAGGTTGCAGTGAGCTGAGATCACATCCCTGCACTCCAGCCTTGGTGACAGAGCGAGACTGCATCTCAAAA
AAAAAAAAATTCTAGTGTTGTTAGCCCTCCCTTATGTGGCACTGCAGCAGGTTACTAATGGACGAGAAGCTGTTGGGGGAAGTAGAGTTG
TAGGGTGTTGGAGCTAGAAAGGCTCTGGAGTGCTCTAGTTTGGGCCTCCAGGTCTCTAGATAGGACAGCCAAGGCCCTGAGACACTGATA
CCATGGCCAAGATGTCCCAGCAGGATGGCAGGCAGTGCCCACAGTCCAGCGCTCATCCCAGCTCCCCAAGGCCTTGGGCTGCAGCCACTC
CACGGTGCCCACTCATAGTGGCAGATTCTTCAACCATCCGGTCTTTGTAAGTTGCTCACTGCCTTCCCCTCTTCCCTGCCTCTTCACCCC
CATGCCCAGATTCCAATTCAGAAGAGGCCCTTCCTGCGTCAGGGAAAAGCAAGTATGAAGCCATGGATTTTGACAGCTTACTGAAAGAGG
CCCAGCAGAGCCTGCATTGATAACAGCCTTAACCCTCGAGGAATACCTCAATACCTCAGACAAGGCCCTTCCAATATGTTTACGTTTTCA

>20399_20399_2_CTNND2-PPARGC1B_CTNND2_chr5_11082808_ENST00000458100_PPARGC1B_chr5_149199996_ENST00000394320_length(amino acids)=1016AA_BP=25
MTVWCARWPLRCGTWPWTSEIRSSSGGGSGEEQLYADFPELDLSQLDASDFDSATCFGELQWCPENSETEPNQYSPDDSELFQIDSENEA
LLAELTKTLDDIPEDDVGLAAFPALDGGDALSCTSASPAPSSAPPSPAPEKPSAPAPEVDELSLLQKLLLATSYPTSSSDTQKEGTAWRQ
AGLRSKSQRPCVKADSTQDKKAPMMQSQSRSCTELHKHLTSAQCCLQDRGLQPPCLQSPRLPAKEDKEPGEDCPSPQPAPASPRDSLALG
RADPGAPVSQEDMQAMVQLIRYMHTYCLPQRKLPPQTPEPLPKACSNPSQQVRSRPWSRHHSKASWAEFSILRELLAQDVLCDVSKPYRL
ATPVYASLTPRSRPRPPKDSQASPGRPSSVEEVRIAASPKSTGPRPSLRPLRLEVKREVRRPARLQQQEEEDEEEEEEEEEEEKEEEEEW
GRKRPGRGLPWTKLGRKLESSVCPVRRSRRLNPELGPWLTFADEPLVPSEPQGALPSLCLAPKAYDVERELGSPTDEDSGQDQQLLRGPQ
IPALESPCESGCGDMDEDPSCPQLPPRDSPRCLMLALSQSDPTFGKKSFEQTLTVELCGTAGLTPPTTPPYKPTEEDPFKPDIKHSLGKE
IALSLPSPEGLSLKATPGAAHKLPKKHPERSELLSHLRHATAQPASQAGQKRPFSCSFGDHDYCQVLRPEGVLQRKVLRSWEPSGVHLED
WPQQGAPWAEAQAPGREEDRSCDAGAPPKDSTLLRDHEIRASLTKHFGLLETALEEEDLASCKSPEYDTVFEDSSSSSGESSFLPEEEEE
EGEEEEEDDEEEDSGVSPTCSDHCPYQSPPSKANRQLCSRSRSSSGSSPCHSWSPATRRNFRCESRGPCSDRTPSIRHARKRREKAIGEG
RVVYIQNLSSDMSSRELKRRFEVFGEIEECEVLTRNRRGEKYGFITYRCSEHAALSLTKGAALRKRNEPSFQLSYGGLRHFCWPRYTDYG

--------------------------------------------------------------
>20399_20399_3_CTNND2-PPARGC1B_CTNND2_chr5_11082808_ENST00000503622_PPARGC1B_chr5_149199996_ENST00000360453_length(transcript)=4860nt_BP=1979nt
AGCCTGGGGAAGGAGGGAAGAGTAACCCTTCATCTTTGGGACTAGTCGTCTTGTTTGCCTAGACTACAGTTTTCAAGTATTTAAGGACCA
TTTATTTCAAAAGGAATTACAGTTTGAAAGGCTGACCCGAGAGCTGGAGGCTGAACGGCAGATCGTAGCCAGCCAGCTGGAGCGATGCAA
GCTCGGATCCGAGACTGGCAGCATGAGCAGCATGAGTTCAGCAGAAGAGCAGTTTCAGTGGCAGTCACAAGATGGTCAAAAAGATATCGA
AGATGAGCTTACAACAGGTCTCGAGCTGGTGGACTCCTGTATTAGGTCACTACAGGAATCAGGAATACTTGACCCACAGGATTATTCTAC
AGGTGAAACTGGTTCCCGAGCCTCATACAGCAGCCAGCATGGGCACCTGGGCCCAGAGTTGCGGGCCCTGCAGTCCCCAGAACACCACAT
AGATCCCATCTATGAAGACCGCGTCTATCAGAAGCCCCCTATGAGGAGTCTCAGCCAGAGCCAGGGGGACCCTCTGCCGCCAGCACACAC
CGGCACCTACCGCACGAGCACAGCCCCATCTTCCCCTGGTGTCGACTCCGTCCCCTTGCAGCGCACAGGCAGCCAGCACGGCCCACAGAA
TGCCGCCGCGGCCACCTTCCAGAGGGCCAGCTATGCCGCCGGCCCAGCCTCCAATTACGCGGACCCCTACCGACAGCTGCAGTATTGTCC
CTCTGTTGAGTCTCCATACAGCAAATCCGGCCCTGCTCTCCCGCCTGAAGGCACCTTGGCCAGGTCCCCGTCCATTGATAGCATTCAGAA
AGATCCCAGAGAATTTGGATGGAGAGACCCGGAACTGCCGGAAGTGATTCAGATGTTGCAGCACCAGTTTCCCTCGGTCCAGTCTAACGC
GGCAGCCTACTTGCAACACCTCTGTTTTGGAGACAACAAAATTAAAGCCGAGATAAGGAGACAAGGAGGCATCCAGCTCCTGGTGGACCT
GTTGGATCATCGGATGACCGAAGTCCACCGTAGTGCCTGTGGAGCTCTGAGAAACCTGGTGTATGGGAAGGCCAACGATGATAACAAAAT
TGCCCTGAAAAACTGTGGTGGCATCCCAGCACTGGTGAGGTTACTCCGCAAGACGACTGACCTGGAGATCCGGGAGCTGGTCACAGGAGT
CCTTTGGAACCTCTCCTCATGCGATGCACTCAAAATGCCAATCATCCAGGATGCCCTAGCAGTACTGACCAACGCGGTGATTATCCCCCA
CTCAGGCTGGGAAAATTCGCCTCTTCAGGATGATCGGAAAATACAGCTGCATTCATCACAGGTGCTGCGTAACGCCACCGGGTGCCTAAG
GAATGTTAGTTCGGCCGGAGAGGAGGCCCGCAGAAGGATGAGAGAGTGTGATGGGCTTACGGATGCCTTGCTGTACGTGATCCAGTCTGC
GCTGGGGAGCAGTGAGATCGATAGCAAGACCGTTGAAAACTGTGTGTGCATTTTAAGGAACCTCTCGTACCGGCTGGCGGCAGAAACGTC
TCAGGGACAGCACATGGGCACGGACGAGCTGGACGGGCTACTCTGTGGCGAGGCCAATGGCAAGGATGCTGAGAGCTCTGGGTGCTGGGG
CAAGAAGAAGAAGAAAAAGAAATCCCAAGATCAGTGGGATGGAGTAGGACCTCTTCCAGACTGTGCTGAACCACCAAAAGGGATCCAGAT
GCTGTGGCACCCATCAATAGTCAAACCCTACCTCACACTGCTCTCTGAGTGCTCAAATCCAGACACGCTGGAAGGGGCGGCAGGCGCCCT
GCAGAACTTGGCTGCAGGGAGCTGGAAGTGGTCAGTATATATCCGAGCCGCTGTCCGAAAAGAGAAAGGCCTGCCCATCCTCGTGGAGCT
GCTCCGAATAGACAATGACCGTGTGGTGTGCGCGGTGGCCACTGCGCTGCGGAACATGGCCTTGGACGTCAGAAATAAGGAGCTCATCGG
GTGGAGGGTCCGGGGAGGAGCAACTCTATGCTGACTTTCCAGAACTTGACCTCTCCCAGCTGGATGCCAGCGACTTTGACTCGGCCACCT
GCTTTGGGGAGCTGCAGTGGTGCCCAGAGAACTCAGAGACTGAACCCAACCAGTACAGCCCCGATGACTCCGAGCTCTTCCAGATTGACA
GTGAGAATGAGGCCCTCCTGGCAGAGCTCACCAAGACCCTGGATGACATCCCTGAAGATGACGTGGGTCTGGCTGCCTTCCCAGCCCTGG
ATGGTGGAGACGCTCTATCATGCACCTCAGCTTCGCCTGCCCCCTCATCTGCACCCCCCAGCCCTGCCCCGGAGAAGCCCTCGGCCCCAG
CCCCTGAGGTGGACGAGCTCTCACTGGCGGACAGCACCCAAGACAAGAAGGCTCCCATGATGCAGTCTCAGAGCCGAAGTTGTACAGAAC
TACATAAGCACCTCACCTCGGCACAGTGCTGCCTGCAGGATCGGGGTCTGCAGCCACCATGCCTCCAGAGTCCCCGGCTCCCTGCCAAGG
AGGACAAGGAGCCGGGTGAGGACTGCCCGAGCCCCCAGCCAGCTCCAGCCTCTCCCCGGGACTCCCTAGCTCTGGGCAGGGCAGACCCCG
GTGCCCCGGTTTCCCAGGAAGACATGCAGGCGATGGTGCAACTCATACGCTACATGCACACCTACTGCCTCCCCCAGAGGAAGCTGCCCC
CACAGACCCCTGAGCCACTCCCCAAGGCCTGCAGCAACCCCTCCCAGCAGGTCAGATCCCGGCCCTGGTCCCGGCACCACTCCAAAGCCT
CCTGGGCTGAGTTCTCCATTCTGAGGGAACTTCTGGCTCAAGACGTGCTCTGTGATGTCAGCAAACCCTACCGTCTGGCCACGCCTGTTT
ATGCCTCCCTCACACCTCGGTCAAGGCCCAGGCCCCCCAAAGACAGTCAGGCCTCCCCTGGTCGCCCGTCCTCGGTGGAGGAGGTAAGGA
TCGCAGCTTCACCCAAGAGCACCGGGCCCAGACCAAGCCTGCGCCCACTGCGGCTGGAGGTGAAAAGGGAGGTCCGCCGGCCTGCCAGAC
TGCAGCAGCAGGAGGAGGAAGACGAGGAAGAAGAGGAGGAGGAAGAGGAAGAAGAAAAAGAGGAGGAGGAGGAGTGGGGCAGGAAAAGGC
CAGGCCGAGGCCTGCCATGGACGAAGCTGGGGAGGAAGCTGGAGAGCTCTGTGTGCCCCGTGCGGCGTTCTCGGAGACTGAACCCTGAGC
TGGGCCCCTGGCTGACATTTGCAGATGAGCCGCTGGTCCCCTCGGAGCCCCAAGGTGCTCTGCCCTCACTGTGCCTGGCTCCCAAGGCCT
ACGACGTAGAGCGGGAGCTGGGCAGCCCCACGGACGAGGACAGTGGCCAAGACCAGCAGCTCCTACGGGGACCCCAGATCCCTGCCCTGG
AGAGCCCCTGTGAGAGTGGGTGTGGGGACATGGATGAGGACCCCAGCTGCCCGCAGCTCCCTCCCAGAGACTCTCCCAGGTGCCTCATGC
TGGCCTTGTCACAAAGCGACCCAACTTTTGGCAAGAAGAGCTTTGAGCAGACCTTGACAGTGGAGCTCTGTGGCACAGCAGGACTCACCC
CACCCACCACACCACCGTACAAGCCCACAGAGGAGGATCCCTTCAAACCAGACATCAAGCATAGTCTAGGCAAAGAAATAGCTCTCAGCC
TCCCCTCCCCTGAGGGCCTCTCACTCAAGGCCACCCCAGGGGCTGCCCACAAGCTGCCAAAGAAGCACCCAGAGCGAAGTGAGCTCCTGT
CCCACCTGCGACATGCCACAGCCCAGCCAGCCTCCCAGGCTGGCCAGAAGCGTCCCTTCTCCTGTTCCTTTGGAGACCATGACTACTGCC
AGGTGCTCCGACCAGAAGGCGTCCTGCAAAGGAAGGTGCTGAGGTCCTGGGAGCCGTCTGGGGTTCACCTTGAGGACTGGCCCCAGCAGG
GTGCCCCTTGGGCTGAGGCACAGGCCCCTGGCAGGGAGGAAGACAGAAGCTGTGATGCTGGCGCCCCACCCAAGGACAGCACGCTGCTGA
GAGACCATGAGATCCGTGCCAGCCTCACCAAACACTTTGGGCTGCTGGAGACCGCCCTGGAGGAGGAAGACCTGGCCTCCTGCAAGAGCC
CTGAGTATGACACTGTCTTTGAAGACAGCAGCAGCAGCAGCGGCGAGAGCAGCTTCCTCCCAGAGGAGGAAGAGGAAGAAGGGGAGGAGG
AGGAGGAGGACGATGAAGAAGAGGACTCAGGGGTCAGCCCCACTTGCTCTGACCACTGCCCCTACCAGAGCCCACCAAGCAAGGCCAACC
GGCAGCTCTGTTCCCGCAGCCGCTCAAGCTCTGGCTCTTCACCCTGCCACTCCTGGTCACCAGCCACTCGAAGGAACTTCAGATGTGAGA
GCAGAGGGCCGTGTTCAGACAGAACGCCAAGCATCCGGCACGCCAGGAAGCGGCGGGAAAAGGCCATTGGGGAAGGCCGCGTGGTGTACA
TTCAAAATCTCTCCAGCGACATGAGCTCCCGAGAGCTGAAGAGGCGCTTTGAAGTGTTTGGTGAGATTGAGGAGTGCGAGGTGCTGACAA
GAAATAGGAGAGGCGAGAAGTACGGCTTCATCACCTACCGGTGTTCTGAGCACGCGGCCCTCTCTTTGACAAAGGGCGCTGCCCTGAGGA
AGCGCAACGAGCCCTCCTTCCAGCTGAGCTACGGAGGGCTCCGGCACTTCTGCTGGCCCAGATACACTGACTACGATTCCAATTCAGAAG
AGGCCCTTCCTGCGTCAGGGAAAAGCAAGTATGAAGCCATGGATTTTGACAGCTTACTGAAAGAGGCCCAGCAGAGCCTGCATTGATAAC

>20399_20399_3_CTNND2-PPARGC1B_CTNND2_chr5_11082808_ENST00000503622_PPARGC1B_chr5_149199996_ENST00000360453_length(amino acids)=983AA_BP=25
MTVWCARWPLRCGTWPWTSEIRSSSGGGSGEEQLYADFPELDLSQLDASDFDSATCFGELQWCPENSETEPNQYSPDDSELFQIDSENEA
LLAELTKTLDDIPEDDVGLAAFPALDGGDALSCTSASPAPSSAPPSPAPEKPSAPAPEVDELSLADSTQDKKAPMMQSQSRSCTELHKHL
TSAQCCLQDRGLQPPCLQSPRLPAKEDKEPGEDCPSPQPAPASPRDSLALGRADPGAPVSQEDMQAMVQLIRYMHTYCLPQRKLPPQTPE
PLPKACSNPSQQVRSRPWSRHHSKASWAEFSILRELLAQDVLCDVSKPYRLATPVYASLTPRSRPRPPKDSQASPGRPSSVEEVRIAASP
KSTGPRPSLRPLRLEVKREVRRPARLQQQEEEDEEEEEEEEEEEKEEEEEWGRKRPGRGLPWTKLGRKLESSVCPVRRSRRLNPELGPWL
TFADEPLVPSEPQGALPSLCLAPKAYDVERELGSPTDEDSGQDQQLLRGPQIPALESPCESGCGDMDEDPSCPQLPPRDSPRCLMLALSQ
SDPTFGKKSFEQTLTVELCGTAGLTPPTTPPYKPTEEDPFKPDIKHSLGKEIALSLPSPEGLSLKATPGAAHKLPKKHPERSELLSHLRH
ATAQPASQAGQKRPFSCSFGDHDYCQVLRPEGVLQRKVLRSWEPSGVHLEDWPQQGAPWAEAQAPGREEDRSCDAGAPPKDSTLLRDHEI
RASLTKHFGLLETALEEEDLASCKSPEYDTVFEDSSSSSGESSFLPEEEEEEGEEEEEDDEEEDSGVSPTCSDHCPYQSPPSKANRQLCS
RSRSSSGSSPCHSWSPATRRNFRCESRGPCSDRTPSIRHARKRREKAIGEGRVVYIQNLSSDMSSRELKRRFEVFGEIEECEVLTRNRRG

--------------------------------------------------------------
>20399_20399_4_CTNND2-PPARGC1B_CTNND2_chr5_11082808_ENST00000503622_PPARGC1B_chr5_149199996_ENST00000394320_length(transcript)=6662nt_BP=1979nt
AGCCTGGGGAAGGAGGGAAGAGTAACCCTTCATCTTTGGGACTAGTCGTCTTGTTTGCCTAGACTACAGTTTTCAAGTATTTAAGGACCA
TTTATTTCAAAAGGAATTACAGTTTGAAAGGCTGACCCGAGAGCTGGAGGCTGAACGGCAGATCGTAGCCAGCCAGCTGGAGCGATGCAA
GCTCGGATCCGAGACTGGCAGCATGAGCAGCATGAGTTCAGCAGAAGAGCAGTTTCAGTGGCAGTCACAAGATGGTCAAAAAGATATCGA
AGATGAGCTTACAACAGGTCTCGAGCTGGTGGACTCCTGTATTAGGTCACTACAGGAATCAGGAATACTTGACCCACAGGATTATTCTAC
AGGTGAAACTGGTTCCCGAGCCTCATACAGCAGCCAGCATGGGCACCTGGGCCCAGAGTTGCGGGCCCTGCAGTCCCCAGAACACCACAT
AGATCCCATCTATGAAGACCGCGTCTATCAGAAGCCCCCTATGAGGAGTCTCAGCCAGAGCCAGGGGGACCCTCTGCCGCCAGCACACAC
CGGCACCTACCGCACGAGCACAGCCCCATCTTCCCCTGGTGTCGACTCCGTCCCCTTGCAGCGCACAGGCAGCCAGCACGGCCCACAGAA
TGCCGCCGCGGCCACCTTCCAGAGGGCCAGCTATGCCGCCGGCCCAGCCTCCAATTACGCGGACCCCTACCGACAGCTGCAGTATTGTCC
CTCTGTTGAGTCTCCATACAGCAAATCCGGCCCTGCTCTCCCGCCTGAAGGCACCTTGGCCAGGTCCCCGTCCATTGATAGCATTCAGAA
AGATCCCAGAGAATTTGGATGGAGAGACCCGGAACTGCCGGAAGTGATTCAGATGTTGCAGCACCAGTTTCCCTCGGTCCAGTCTAACGC
GGCAGCCTACTTGCAACACCTCTGTTTTGGAGACAACAAAATTAAAGCCGAGATAAGGAGACAAGGAGGCATCCAGCTCCTGGTGGACCT
GTTGGATCATCGGATGACCGAAGTCCACCGTAGTGCCTGTGGAGCTCTGAGAAACCTGGTGTATGGGAAGGCCAACGATGATAACAAAAT
TGCCCTGAAAAACTGTGGTGGCATCCCAGCACTGGTGAGGTTACTCCGCAAGACGACTGACCTGGAGATCCGGGAGCTGGTCACAGGAGT
CCTTTGGAACCTCTCCTCATGCGATGCACTCAAAATGCCAATCATCCAGGATGCCCTAGCAGTACTGACCAACGCGGTGATTATCCCCCA
CTCAGGCTGGGAAAATTCGCCTCTTCAGGATGATCGGAAAATACAGCTGCATTCATCACAGGTGCTGCGTAACGCCACCGGGTGCCTAAG
GAATGTTAGTTCGGCCGGAGAGGAGGCCCGCAGAAGGATGAGAGAGTGTGATGGGCTTACGGATGCCTTGCTGTACGTGATCCAGTCTGC
GCTGGGGAGCAGTGAGATCGATAGCAAGACCGTTGAAAACTGTGTGTGCATTTTAAGGAACCTCTCGTACCGGCTGGCGGCAGAAACGTC
TCAGGGACAGCACATGGGCACGGACGAGCTGGACGGGCTACTCTGTGGCGAGGCCAATGGCAAGGATGCTGAGAGCTCTGGGTGCTGGGG
CAAGAAGAAGAAGAAAAAGAAATCCCAAGATCAGTGGGATGGAGTAGGACCTCTTCCAGACTGTGCTGAACCACCAAAAGGGATCCAGAT
GCTGTGGCACCCATCAATAGTCAAACCCTACCTCACACTGCTCTCTGAGTGCTCAAATCCAGACACGCTGGAAGGGGCGGCAGGCGCCCT
GCAGAACTTGGCTGCAGGGAGCTGGAAGTGGTCAGTATATATCCGAGCCGCTGTCCGAAAAGAGAAAGGCCTGCCCATCCTCGTGGAGCT
GCTCCGAATAGACAATGACCGTGTGGTGTGCGCGGTGGCCACTGCGCTGCGGAACATGGCCTTGGACGTCAGAAATAAGGAGCTCATCGG
GTGGAGGGTCCGGGGAGGAGCAACTCTATGCTGACTTTCCAGAACTTGACCTCTCCCAGCTGGATGCCAGCGACTTTGACTCGGCCACCT
GCTTTGGGGAGCTGCAGTGGTGCCCAGAGAACTCAGAGACTGAACCCAACCAGTACAGCCCCGATGACTCCGAGCTCTTCCAGATTGACA
GTGAGAATGAGGCCCTCCTGGCAGAGCTCACCAAGACCCTGGATGACATCCCTGAAGATGACGTGGGTCTGGCTGCCTTCCCAGCCCTGG
ATGGTGGAGACGCTCTATCATGCACCTCAGCTTCGCCTGCCCCCTCATCTGCACCCCCCAGCCCTGCCCCGGAGAAGCCCTCGGCCCCAG
CCCCTGAGGTGGACGAGCTCTCACTGCTGCAGAAGCTCCTCCTGGCCACATCCTACCCAACATCAAGCTCTGACACCCAGAAGGAAGGGA
CCGCCTGGCGCCAGGCAGGCCTCAGATCTAAAAGTCAACGGCCTTGTGTTAAGGCGGACAGCACCCAAGACAAGAAGGCTCCCATGATGC
AGTCTCAGAGCCGAAGTTGTACAGAACTACATAAGCACCTCACCTCGGCACAGTGCTGCCTGCAGGATCGGGGTCTGCAGCCACCATGCC
TCCAGAGTCCCCGGCTCCCTGCCAAGGAGGACAAGGAGCCGGGTGAGGACTGCCCGAGCCCCCAGCCAGCTCCAGCCTCTCCCCGGGACT
CCCTAGCTCTGGGCAGGGCAGACCCCGGTGCCCCGGTTTCCCAGGAAGACATGCAGGCGATGGTGCAACTCATACGCTACATGCACACCT
ACTGCCTCCCCCAGAGGAAGCTGCCCCCACAGACCCCTGAGCCACTCCCCAAGGCCTGCAGCAACCCCTCCCAGCAGGTCAGATCCCGGC
CCTGGTCCCGGCACCACTCCAAAGCCTCCTGGGCTGAGTTCTCCATTCTGAGGGAACTTCTGGCTCAAGACGTGCTCTGTGATGTCAGCA
AACCCTACCGTCTGGCCACGCCTGTTTATGCCTCCCTCACACCTCGGTCAAGGCCCAGGCCCCCCAAAGACAGTCAGGCCTCCCCTGGTC
GCCCGTCCTCGGTGGAGGAGGTAAGGATCGCAGCTTCACCCAAGAGCACCGGGCCCAGACCAAGCCTGCGCCCACTGCGGCTGGAGGTGA
AAAGGGAGGTCCGCCGGCCTGCCAGACTGCAGCAGCAGGAGGAGGAAGACGAGGAAGAAGAGGAGGAGGAAGAGGAAGAAGAAAAAGAGG
AGGAGGAGGAGTGGGGCAGGAAAAGGCCAGGCCGAGGCCTGCCATGGACGAAGCTGGGGAGGAAGCTGGAGAGCTCTGTGTGCCCCGTGC
GGCGTTCTCGGAGACTGAACCCTGAGCTGGGCCCCTGGCTGACATTTGCAGATGAGCCGCTGGTCCCCTCGGAGCCCCAAGGTGCTCTGC
CCTCACTGTGCCTGGCTCCCAAGGCCTACGACGTAGAGCGGGAGCTGGGCAGCCCCACGGACGAGGACAGTGGCCAAGACCAGCAGCTCC
TACGGGGACCCCAGATCCCTGCCCTGGAGAGCCCCTGTGAGAGTGGGTGTGGGGACATGGATGAGGACCCCAGCTGCCCGCAGCTCCCTC
CCAGAGACTCTCCCAGGTGCCTCATGCTGGCCTTGTCACAAAGCGACCCAACTTTTGGCAAGAAGAGCTTTGAGCAGACCTTGACAGTGG
AGCTCTGTGGCACAGCAGGACTCACCCCACCCACCACACCACCGTACAAGCCCACAGAGGAGGATCCCTTCAAACCAGACATCAAGCATA
GTCTAGGCAAAGAAATAGCTCTCAGCCTCCCCTCCCCTGAGGGCCTCTCACTCAAGGCCACCCCAGGGGCTGCCCACAAGCTGCCAAAGA
AGCACCCAGAGCGAAGTGAGCTCCTGTCCCACCTGCGACATGCCACAGCCCAGCCAGCCTCCCAGGCTGGCCAGAAGCGTCCCTTCTCCT
GTTCCTTTGGAGACCATGACTACTGCCAGGTGCTCCGACCAGAAGGCGTCCTGCAAAGGAAGGTGCTGAGGTCCTGGGAGCCGTCTGGGG
TTCACCTTGAGGACTGGCCCCAGCAGGGTGCCCCTTGGGCTGAGGCACAGGCCCCTGGCAGGGAGGAAGACAGAAGCTGTGATGCTGGCG
CCCCACCCAAGGACAGCACGCTGCTGAGAGACCATGAGATCCGTGCCAGCCTCACCAAACACTTTGGGCTGCTGGAGACCGCCCTGGAGG
AGGAAGACCTGGCCTCCTGCAAGAGCCCTGAGTATGACACTGTCTTTGAAGACAGCAGCAGCAGCAGCGGCGAGAGCAGCTTCCTCCCAG
AGGAGGAAGAGGAAGAAGGGGAGGAGGAGGAGGAGGACGATGAAGAAGAGGACTCAGGGGTCAGCCCCACTTGCTCTGACCACTGCCCCT
ACCAGAGCCCACCAAGCAAGGCCAACCGGCAGCTCTGTTCCCGCAGCCGCTCAAGCTCTGGCTCTTCACCCTGCCACTCCTGGTCACCAG
CCACTCGAAGGAACTTCAGATGTGAGAGCAGAGGGCCGTGTTCAGACAGAACGCCAAGCATCCGGCACGCCAGGAAGCGGCGGGAAAAGG
CCATTGGGGAAGGCCGCGTGGTGTACATTCAAAATCTCTCCAGCGACATGAGCTCCCGAGAGCTGAAGAGGCGCTTTGAAGTGTTTGGTG
AGATTGAGGAGTGCGAGGTGCTGACAAGAAATAGGAGAGGCGAGAAGTACGGCTTCATCACCTACCGGTGTTCTGAGCACGCGGCCCTCT
CTTTGACAAAGGGCGCTGCCCTGAGGAAGCGCAACGAGCCCTCCTTCCAGCTGAGCTACGGAGGGCTCCGGCACTTCTGCTGGCCCAGAT
ACACTGACTACGGTAAGCCCCTGAAACCCAGCCACAGTCTAGTAAGACTCAAAGCTTGGGAAGCAGTGCCTTCCTTGAACAAAACCCAGA
GCTAAAGCGCCTTGTGGACATAGCTTCCATCCCCACACCCCAGTGTGCTGCTTGGTATAACTTTGCAGCCACTTTGCCTGAAGACTACCA
TCCTGTTTCTCTTCTGGCCTCTGGTCCACCTTATCCTGTCCTGTGACTGCTACCAAAGAGAATCCAGCCTCCCACGGCCTCTAGGAAGAT
TCAGTCATGTGCACAGCCAGCTGGCAGAACCGTGGCTACGGTCTCCTTGACTTCACAGGGCCAGCTGCTACCCTGTCCCCTTCAGGGGCA
TTCCGTGGTGACCCCAGACAAGGCAGCAGCCACCTGGGGACAAGATGATGAAGAAGGACAAAGAAGTACAATGTACGAAAGAATTACTTG
GCCAGGCTCAGTGGCTCATGCCTGTAATCCCATCACCTTGGGAGGCTGAGGCAAGAGGATCACTTGAGCCCAGGAGTTCGAGACCAGCTT
GGGCAACATAGTGAAATCCTGTCTCTACAAAAAATATAAAAATTAGCCAGGCATGGTGGCTTGCGCCTATAGTCCCAGCTACTCAGGAGG
CAGAGGTGGGAGGATCACCTGAACCCAAGAGGTTGGAGCTGCAGTGAGCCATGATGGCACTACTGCATTCCAGCCTGGGCAACAGAGCAA
GACCCTGTCTCAAAAGGAAAGAAAAAAAAAAAAACACTTACTGGAGAGAATCCAATGCAGCCTTGATGGTACAGGACTGAGTGTCAGTGA
CCCGGCTGGGTGCCAGGCCAGGCGGCCCTGCCCTTGGCTGCATGTCCATTTATGGGAATCAGTTTCCCAATCTATTAAAAAATTCTAGTG
TTGGCTGGGTGCAGTTGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGAAGATCATGAGGTCAAGAGATCGAGACCATCG
TGGCCAACATGGTGAAACCCCCTCTCTATTAAAAATACAAAAATTAGCTGGGCGTGGTGGCGCACACCTGTAGTCCCAGCAACTTGGGAG
GCTGAGGCGGGAGAATCACTTGAACCCGAGAGGCAGAGGTTGCAGTGAGCTGAGATCACATCCCTGCACTCCAGCCTTGGTGACAGAGCG
AGACTGCATCTCAAAAAAAAAAAAATTCTAGTGTTGTTAGCCCTCCCTTATGTGGCACTGCAGCAGGTTACTAATGGACGAGAAGCTGTT
GGGGGAAGTAGAGTTGTAGGGTGTTGGAGCTAGAAAGGCTCTGGAGTGCTCTAGTTTGGGCCTCCAGGTCTCTAGATAGGACAGCCAAGG
CCCTGAGACACTGATACCATGGCCAAGATGTCCCAGCAGGATGGCAGGCAGTGCCCACAGTCCAGCGCTCATCCCAGCTCCCCAAGGCCT
TGGGCTGCAGCCACTCCACGGTGCCCACTCATAGTGGCAGATTCTTCAACCATCCGGTCTTTGTAAGTTGCTCACTGCCTTCCCCTCTTC
CCTGCCTCTTCACCCCCATGCCCAGATTCCAATTCAGAAGAGGCCCTTCCTGCGTCAGGGAAAAGCAAGTATGAAGCCATGGATTTTGAC
AGCTTACTGAAAGAGGCCCAGCAGAGCCTGCATTGATAACAGCCTTAACCCTCGAGGAATACCTCAATACCTCAGACAAGGCCCTTCCAA
TATGTTTACGTTTTCAAAGAAATCAAGTATATGAGGAGAGCGAGCGAGCGTGAGAGAACACCCGTGAGAGAGACTTGAAACTGCTGTCCT

>20399_20399_4_CTNND2-PPARGC1B_CTNND2_chr5_11082808_ENST00000503622_PPARGC1B_chr5_149199996_ENST00000394320_length(amino acids)=1016AA_BP=25
MTVWCARWPLRCGTWPWTSEIRSSSGGGSGEEQLYADFPELDLSQLDASDFDSATCFGELQWCPENSETEPNQYSPDDSELFQIDSENEA
LLAELTKTLDDIPEDDVGLAAFPALDGGDALSCTSASPAPSSAPPSPAPEKPSAPAPEVDELSLLQKLLLATSYPTSSSDTQKEGTAWRQ
AGLRSKSQRPCVKADSTQDKKAPMMQSQSRSCTELHKHLTSAQCCLQDRGLQPPCLQSPRLPAKEDKEPGEDCPSPQPAPASPRDSLALG
RADPGAPVSQEDMQAMVQLIRYMHTYCLPQRKLPPQTPEPLPKACSNPSQQVRSRPWSRHHSKASWAEFSILRELLAQDVLCDVSKPYRL
ATPVYASLTPRSRPRPPKDSQASPGRPSSVEEVRIAASPKSTGPRPSLRPLRLEVKREVRRPARLQQQEEEDEEEEEEEEEEEKEEEEEW
GRKRPGRGLPWTKLGRKLESSVCPVRRSRRLNPELGPWLTFADEPLVPSEPQGALPSLCLAPKAYDVERELGSPTDEDSGQDQQLLRGPQ
IPALESPCESGCGDMDEDPSCPQLPPRDSPRCLMLALSQSDPTFGKKSFEQTLTVELCGTAGLTPPTTPPYKPTEEDPFKPDIKHSLGKE
IALSLPSPEGLSLKATPGAAHKLPKKHPERSELLSHLRHATAQPASQAGQKRPFSCSFGDHDYCQVLRPEGVLQRKVLRSWEPSGVHLED
WPQQGAPWAEAQAPGREEDRSCDAGAPPKDSTLLRDHEIRASLTKHFGLLETALEEEDLASCKSPEYDTVFEDSSSSSGESSFLPEEEEE
EGEEEEEDDEEEDSGVSPTCSDHCPYQSPPSKANRQLCSRSRSSSGSSPCHSWSPATRRNFRCESRGPCSDRTPSIRHARKRREKAIGEG
RVVYIQNLSSDMSSRELKRRFEVFGEIEECEVLTRNRRGEKYGFITYRCSEHAALSLTKGAALRKRNEPSFQLSYGGLRHFCWPRYTDYG

--------------------------------------------------------------
>20399_20399_5_CTNND2-PPARGC1B_CTNND2_chr5_11082808_ENST00000511377_PPARGC1B_chr5_149199996_ENST00000360453_length(transcript)=5769nt_BP=2888nt
ACTGTTTGCGAGTGAAAGCAGAAATTACCATAGGATAATTCAGCGTCCTGACTTTTTCGAGGCTGTTCTTCACTCCCTTCTCGGTTTTTG
AGCTGCTCTGTGGTTCCTTTTAGCCGTGGTGCAGGGAGGGAGGAGGGAGGTGGGTAGGATGCCAGGAACCGCCTGCTCCACAGCCTGGGG
AAGGAGGGAAGAGTAACCCTTCATCTTTGGGACTAGTCGTCTTGTTTGCCTAGACTACAGTTTTCAAGTATTTAAGGACCATTTATTTCA
AAAGGAATTACAGTTTGAAAGGCTGACCCGAGAGCTGGAGGCTGAACGGCAGATCGTAGCCAGCCAGCTGGAGCGATGCAAGCTCGGATC
CGAGACTGGCAGCATGAGCAGCATGAGTTCAGCAGAAGAGCAGTTTCAGTGGCAGTCACAAGATGGTCAAAAAGATATCGAAGATGAGCT
TACAACAGGTCTCGAGCTGGTGGACTCCTGTATTAGGTCACTACAGGAATCAGGAATACTTGACCCACAGGATTATTCTACAGGTGAAAG
GCCCAGCCTGCTCTCCCAGAGTGCACTTCAGCTCAATTCCAAACCTGAAGGGTCTTTCCAGTATCCGGCCAGCTACCATAGCAACCAGAC
CCTGGCCCTGGGGGAAACCACCCCTTCACAGCTCCCGGCCCGAGGCACACAAGCCCGAGCTACGGGCCAGAGCTTCAGCCAGGGCACGAC
CAGCCGCGCCGGCCACCTGGCGGGGCCCGAGCCCGCGCCGCCGCCGCCGCCGCCGCCGCGGGAGCCGTTCGCGCCCAGCCTGGGCAGCGC
CTTCCACCTGCCCGACGCGCCGCCCGCCGCCGCCGCCGCCGCGCTCTACTACTCCAGCTCCACGCTGCCCGCGCCGCCGCGCGGGGGCTC
CCCGCTGGCCGCGCCCCAGGGCGGTTCGCCCACCAAGCTGCAGCGCGGCGGCTCGGCCCCCGAGGGCGCCACCTACGCCGCGCCGCGCGG
CTCCTCGCCCAAGCAGTCGCCCAGCCGCCTGGCCAAGTCCTACAGCACCAGCTCGCCCATCAACATCGTCGTGTCCTCGGCCGGCCTGTC
CCCGATCCGCGTGACCTCGCCCCCCACCGTGCAGTCCACCATCTCCTCCTCGCCCATCCACCAGCTGAGCTCCACCATCGGCACGTACGC
CACCCTGTCGCCCACCAAGCGCCTGGTCCACGCGTCCGAGCAGTACAGCAAGCACTCGCAGGAGCTGTATGCCACGGCCACCCTCCAGAG
GCCGGGCAGCCTGGCAGCTGGTTCCCGAGCCTCATACAGCAGCCAGCATGGGCACCTGGGCCCAGAGTTGCGGGCCCTGCAGTCCCCAGA
ACACCACATAGATCCCATCTATGAAGACCGCGTCTATCAGAAGCCCCCTATGAGGAGTCTCAGCCAGAGCCAGGGGGACCCTCTGCCGCC
AGCACACACCGGCACCTACCGCACGAGCACAGCCCCATCTTCCCCTGGTGTCGACTCCGTCCCCTTGCAGCGCACAGGCAGCCAGCACGG
CCCACAGAATGCCGCCGCGGCCACCTTCCAGAGGGCCAGCTATGCCGCCGGCCCAGCCTCCAATTACGCGGACCCCTACCGACAGCTGCA
GTATTGTCCCTCTGTTGAGTCTCCATACAGCAAATCCGGCCCTGCTCTCCCGCCTGAAGGCACCTTGGCCAGGTCCCCGTCCATTGATAG
CATTCAGAAAGATCCCAGAGAATTTGGATGGAGAGACCCGGAACTGCCGGAAGTGATTCAGATGTTGCAGCACCAGTTTCCCTCGGTCCA
GTCTAACGCGGCAGCCTACTTGCAACACCTCTGTTTTGGAGACAACAAAATTAAAGCCGAGATAAGGAGACAAGGAGGCATCCAGCTCCT
GGTGGACCTGTTGGATCATCGGATGACCGAAGTCCACCGTAGTGCCTGTGGAGCTCTGAGAAACCTGGTGTATGGGAAGGCCAACGATGA
TAACAAAATTGCCCTGAAAAACTGTGGTGGCATCCCAGCACTGGTGAGGTTACTCCGCAAGACGACTGACCTGGAGATCCGGGAGCTGGT
CACAGGAGTCCTTTGGAACCTCTCCTCATGCGATGCACTCAAAATGCCAATCATCCAGGATGCCCTAGCAGTACTGACCAACGCGGTGAT
TATCCCCCACTCAGGCTGGGAAAATTCGCCTCTTCAGGATGATCGGAAAATACAGCTGCATTCATCACAGGTGCTGCGTAACGCCACCGG
GTGCCTAAGGAATGTTAGTTCGGCCGGAGAGGAGGCCCGCAGAAGGATGAGAGAGTGTGATGGGCTTACGGATGCCTTGCTGTACGTGAT
CCAGTCTGCGCTGGGGAGCAGTGAGATCGATAGCAAGACCGTTGAAAACTGTGTGTGCATTTTAAGGAACCTCTCGTACCGGCTGGCGGC
AGAAACGTCTCAGGGACAGCACATGGGCACGGACGAGCTGGACGGGCTACTCTGTGGCGAGGCCAATGGCAAGGATGCTGAGAGCTCTGG
GTGCTGGGGCAAGAAGAAGAAGAAAAAGAAATCCCAAGATCAGTGGGATGGAGTAGGACCTCTTCCAGACTGTGCTGAACCACCAAAAGG
GATCCAGATGCTGTGGCACCCATCAATAGTCAAACCCTACCTCACACTGCTCTCTGAGTGCTCAAATCCAGACACGCTGGAAGGGGCGGC
AGGCGCCCTGCAGAACTTGGCTGCAGGGAGCTGGAAGTGGTCAGTATATATCCGAGCCGCTGTCCGAAAAGAGAAAGGCCTGCCCATCCT
CGTGGAGCTGCTCCGAATAGACAATGACCGTGTGGTGTGCGCGGTGGCCACTGCGCTGCGGAACATGGCCTTGGACGTCAGAAATAAGGA
GCTCATCGGGTGGAGGGTCCGGGGAGGAGCAACTCTATGCTGACTTTCCAGAACTTGACCTCTCCCAGCTGGATGCCAGCGACTTTGACT
CGGCCACCTGCTTTGGGGAGCTGCAGTGGTGCCCAGAGAACTCAGAGACTGAACCCAACCAGTACAGCCCCGATGACTCCGAGCTCTTCC
AGATTGACAGTGAGAATGAGGCCCTCCTGGCAGAGCTCACCAAGACCCTGGATGACATCCCTGAAGATGACGTGGGTCTGGCTGCCTTCC
CAGCCCTGGATGGTGGAGACGCTCTATCATGCACCTCAGCTTCGCCTGCCCCCTCATCTGCACCCCCCAGCCCTGCCCCGGAGAAGCCCT
CGGCCCCAGCCCCTGAGGTGGACGAGCTCTCACTGGCGGACAGCACCCAAGACAAGAAGGCTCCCATGATGCAGTCTCAGAGCCGAAGTT
GTACAGAACTACATAAGCACCTCACCTCGGCACAGTGCTGCCTGCAGGATCGGGGTCTGCAGCCACCATGCCTCCAGAGTCCCCGGCTCC
CTGCCAAGGAGGACAAGGAGCCGGGTGAGGACTGCCCGAGCCCCCAGCCAGCTCCAGCCTCTCCCCGGGACTCCCTAGCTCTGGGCAGGG
CAGACCCCGGTGCCCCGGTTTCCCAGGAAGACATGCAGGCGATGGTGCAACTCATACGCTACATGCACACCTACTGCCTCCCCCAGAGGA
AGCTGCCCCCACAGACCCCTGAGCCACTCCCCAAGGCCTGCAGCAACCCCTCCCAGCAGGTCAGATCCCGGCCCTGGTCCCGGCACCACT
CCAAAGCCTCCTGGGCTGAGTTCTCCATTCTGAGGGAACTTCTGGCTCAAGACGTGCTCTGTGATGTCAGCAAACCCTACCGTCTGGCCA
CGCCTGTTTATGCCTCCCTCACACCTCGGTCAAGGCCCAGGCCCCCCAAAGACAGTCAGGCCTCCCCTGGTCGCCCGTCCTCGGTGGAGG
AGGTAAGGATCGCAGCTTCACCCAAGAGCACCGGGCCCAGACCAAGCCTGCGCCCACTGCGGCTGGAGGTGAAAAGGGAGGTCCGCCGGC
CTGCCAGACTGCAGCAGCAGGAGGAGGAAGACGAGGAAGAAGAGGAGGAGGAAGAGGAAGAAGAAAAAGAGGAGGAGGAGGAGTGGGGCA
GGAAAAGGCCAGGCCGAGGCCTGCCATGGACGAAGCTGGGGAGGAAGCTGGAGAGCTCTGTGTGCCCCGTGCGGCGTTCTCGGAGACTGA
ACCCTGAGCTGGGCCCCTGGCTGACATTTGCAGATGAGCCGCTGGTCCCCTCGGAGCCCCAAGGTGCTCTGCCCTCACTGTGCCTGGCTC
CCAAGGCCTACGACGTAGAGCGGGAGCTGGGCAGCCCCACGGACGAGGACAGTGGCCAAGACCAGCAGCTCCTACGGGGACCCCAGATCC
CTGCCCTGGAGAGCCCCTGTGAGAGTGGGTGTGGGGACATGGATGAGGACCCCAGCTGCCCGCAGCTCCCTCCCAGAGACTCTCCCAGGT
GCCTCATGCTGGCCTTGTCACAAAGCGACCCAACTTTTGGCAAGAAGAGCTTTGAGCAGACCTTGACAGTGGAGCTCTGTGGCACAGCAG
GACTCACCCCACCCACCACACCACCGTACAAGCCCACAGAGGAGGATCCCTTCAAACCAGACATCAAGCATAGTCTAGGCAAAGAAATAG
CTCTCAGCCTCCCCTCCCCTGAGGGCCTCTCACTCAAGGCCACCCCAGGGGCTGCCCACAAGCTGCCAAAGAAGCACCCAGAGCGAAGTG
AGCTCCTGTCCCACCTGCGACATGCCACAGCCCAGCCAGCCTCCCAGGCTGGCCAGAAGCGTCCCTTCTCCTGTTCCTTTGGAGACCATG
ACTACTGCCAGGTGCTCCGACCAGAAGGCGTCCTGCAAAGGAAGGTGCTGAGGTCCTGGGAGCCGTCTGGGGTTCACCTTGAGGACTGGC
CCCAGCAGGGTGCCCCTTGGGCTGAGGCACAGGCCCCTGGCAGGGAGGAAGACAGAAGCTGTGATGCTGGCGCCCCACCCAAGGACAGCA
CGCTGCTGAGAGACCATGAGATCCGTGCCAGCCTCACCAAACACTTTGGGCTGCTGGAGACCGCCCTGGAGGAGGAAGACCTGGCCTCCT
GCAAGAGCCCTGAGTATGACACTGTCTTTGAAGACAGCAGCAGCAGCAGCGGCGAGAGCAGCTTCCTCCCAGAGGAGGAAGAGGAAGAAG
GGGAGGAGGAGGAGGAGGACGATGAAGAAGAGGACTCAGGGGTCAGCCCCACTTGCTCTGACCACTGCCCCTACCAGAGCCCACCAAGCA
AGGCCAACCGGCAGCTCTGTTCCCGCAGCCGCTCAAGCTCTGGCTCTTCACCCTGCCACTCCTGGTCACCAGCCACTCGAAGGAACTTCA
GATGTGAGAGCAGAGGGCCGTGTTCAGACAGAACGCCAAGCATCCGGCACGCCAGGAAGCGGCGGGAAAAGGCCATTGGGGAAGGCCGCG
TGGTGTACATTCAAAATCTCTCCAGCGACATGAGCTCCCGAGAGCTGAAGAGGCGCTTTGAAGTGTTTGGTGAGATTGAGGAGTGCGAGG
TGCTGACAAGAAATAGGAGAGGCGAGAAGTACGGCTTCATCACCTACCGGTGTTCTGAGCACGCGGCCCTCTCTTTGACAAAGGGCGCTG
CCCTGAGGAAGCGCAACGAGCCCTCCTTCCAGCTGAGCTACGGAGGGCTCCGGCACTTCTGCTGGCCCAGATACACTGACTACGATTCCA
ATTCAGAAGAGGCCCTTCCTGCGTCAGGGAAAAGCAAGTATGAAGCCATGGATTTTGACAGCTTACTGAAAGAGGCCCAGCAGAGCCTGC

>20399_20399_5_CTNND2-PPARGC1B_CTNND2_chr5_11082808_ENST00000511377_PPARGC1B_chr5_149199996_ENST00000360453_length(amino acids)=983AA_BP=25
MTVWCARWPLRCGTWPWTSEIRSSSGGGSGEEQLYADFPELDLSQLDASDFDSATCFGELQWCPENSETEPNQYSPDDSELFQIDSENEA
LLAELTKTLDDIPEDDVGLAAFPALDGGDALSCTSASPAPSSAPPSPAPEKPSAPAPEVDELSLADSTQDKKAPMMQSQSRSCTELHKHL
TSAQCCLQDRGLQPPCLQSPRLPAKEDKEPGEDCPSPQPAPASPRDSLALGRADPGAPVSQEDMQAMVQLIRYMHTYCLPQRKLPPQTPE
PLPKACSNPSQQVRSRPWSRHHSKASWAEFSILRELLAQDVLCDVSKPYRLATPVYASLTPRSRPRPPKDSQASPGRPSSVEEVRIAASP
KSTGPRPSLRPLRLEVKREVRRPARLQQQEEEDEEEEEEEEEEEKEEEEEWGRKRPGRGLPWTKLGRKLESSVCPVRRSRRLNPELGPWL
TFADEPLVPSEPQGALPSLCLAPKAYDVERELGSPTDEDSGQDQQLLRGPQIPALESPCESGCGDMDEDPSCPQLPPRDSPRCLMLALSQ
SDPTFGKKSFEQTLTVELCGTAGLTPPTTPPYKPTEEDPFKPDIKHSLGKEIALSLPSPEGLSLKATPGAAHKLPKKHPERSELLSHLRH
ATAQPASQAGQKRPFSCSFGDHDYCQVLRPEGVLQRKVLRSWEPSGVHLEDWPQQGAPWAEAQAPGREEDRSCDAGAPPKDSTLLRDHEI
RASLTKHFGLLETALEEEDLASCKSPEYDTVFEDSSSSSGESSFLPEEEEEEGEEEEEDDEEEDSGVSPTCSDHCPYQSPPSKANRQLCS
RSRSSSGSSPCHSWSPATRRNFRCESRGPCSDRTPSIRHARKRREKAIGEGRVVYIQNLSSDMSSRELKRRFEVFGEIEECEVLTRNRRG

--------------------------------------------------------------
>20399_20399_6_CTNND2-PPARGC1B_CTNND2_chr5_11082808_ENST00000511377_PPARGC1B_chr5_149199996_ENST00000394320_length(transcript)=7571nt_BP=2888nt
ACTGTTTGCGAGTGAAAGCAGAAATTACCATAGGATAATTCAGCGTCCTGACTTTTTCGAGGCTGTTCTTCACTCCCTTCTCGGTTTTTG
AGCTGCTCTGTGGTTCCTTTTAGCCGTGGTGCAGGGAGGGAGGAGGGAGGTGGGTAGGATGCCAGGAACCGCCTGCTCCACAGCCTGGGG
AAGGAGGGAAGAGTAACCCTTCATCTTTGGGACTAGTCGTCTTGTTTGCCTAGACTACAGTTTTCAAGTATTTAAGGACCATTTATTTCA
AAAGGAATTACAGTTTGAAAGGCTGACCCGAGAGCTGGAGGCTGAACGGCAGATCGTAGCCAGCCAGCTGGAGCGATGCAAGCTCGGATC
CGAGACTGGCAGCATGAGCAGCATGAGTTCAGCAGAAGAGCAGTTTCAGTGGCAGTCACAAGATGGTCAAAAAGATATCGAAGATGAGCT
TACAACAGGTCTCGAGCTGGTGGACTCCTGTATTAGGTCACTACAGGAATCAGGAATACTTGACCCACAGGATTATTCTACAGGTGAAAG
GCCCAGCCTGCTCTCCCAGAGTGCACTTCAGCTCAATTCCAAACCTGAAGGGTCTTTCCAGTATCCGGCCAGCTACCATAGCAACCAGAC
CCTGGCCCTGGGGGAAACCACCCCTTCACAGCTCCCGGCCCGAGGCACACAAGCCCGAGCTACGGGCCAGAGCTTCAGCCAGGGCACGAC
CAGCCGCGCCGGCCACCTGGCGGGGCCCGAGCCCGCGCCGCCGCCGCCGCCGCCGCCGCGGGAGCCGTTCGCGCCCAGCCTGGGCAGCGC
CTTCCACCTGCCCGACGCGCCGCCCGCCGCCGCCGCCGCCGCGCTCTACTACTCCAGCTCCACGCTGCCCGCGCCGCCGCGCGGGGGCTC
CCCGCTGGCCGCGCCCCAGGGCGGTTCGCCCACCAAGCTGCAGCGCGGCGGCTCGGCCCCCGAGGGCGCCACCTACGCCGCGCCGCGCGG
CTCCTCGCCCAAGCAGTCGCCCAGCCGCCTGGCCAAGTCCTACAGCACCAGCTCGCCCATCAACATCGTCGTGTCCTCGGCCGGCCTGTC
CCCGATCCGCGTGACCTCGCCCCCCACCGTGCAGTCCACCATCTCCTCCTCGCCCATCCACCAGCTGAGCTCCACCATCGGCACGTACGC
CACCCTGTCGCCCACCAAGCGCCTGGTCCACGCGTCCGAGCAGTACAGCAAGCACTCGCAGGAGCTGTATGCCACGGCCACCCTCCAGAG
GCCGGGCAGCCTGGCAGCTGGTTCCCGAGCCTCATACAGCAGCCAGCATGGGCACCTGGGCCCAGAGTTGCGGGCCCTGCAGTCCCCAGA
ACACCACATAGATCCCATCTATGAAGACCGCGTCTATCAGAAGCCCCCTATGAGGAGTCTCAGCCAGAGCCAGGGGGACCCTCTGCCGCC
AGCACACACCGGCACCTACCGCACGAGCACAGCCCCATCTTCCCCTGGTGTCGACTCCGTCCCCTTGCAGCGCACAGGCAGCCAGCACGG
CCCACAGAATGCCGCCGCGGCCACCTTCCAGAGGGCCAGCTATGCCGCCGGCCCAGCCTCCAATTACGCGGACCCCTACCGACAGCTGCA
GTATTGTCCCTCTGTTGAGTCTCCATACAGCAAATCCGGCCCTGCTCTCCCGCCTGAAGGCACCTTGGCCAGGTCCCCGTCCATTGATAG
CATTCAGAAAGATCCCAGAGAATTTGGATGGAGAGACCCGGAACTGCCGGAAGTGATTCAGATGTTGCAGCACCAGTTTCCCTCGGTCCA
GTCTAACGCGGCAGCCTACTTGCAACACCTCTGTTTTGGAGACAACAAAATTAAAGCCGAGATAAGGAGACAAGGAGGCATCCAGCTCCT
GGTGGACCTGTTGGATCATCGGATGACCGAAGTCCACCGTAGTGCCTGTGGAGCTCTGAGAAACCTGGTGTATGGGAAGGCCAACGATGA
TAACAAAATTGCCCTGAAAAACTGTGGTGGCATCCCAGCACTGGTGAGGTTACTCCGCAAGACGACTGACCTGGAGATCCGGGAGCTGGT
CACAGGAGTCCTTTGGAACCTCTCCTCATGCGATGCACTCAAAATGCCAATCATCCAGGATGCCCTAGCAGTACTGACCAACGCGGTGAT
TATCCCCCACTCAGGCTGGGAAAATTCGCCTCTTCAGGATGATCGGAAAATACAGCTGCATTCATCACAGGTGCTGCGTAACGCCACCGG
GTGCCTAAGGAATGTTAGTTCGGCCGGAGAGGAGGCCCGCAGAAGGATGAGAGAGTGTGATGGGCTTACGGATGCCTTGCTGTACGTGAT
CCAGTCTGCGCTGGGGAGCAGTGAGATCGATAGCAAGACCGTTGAAAACTGTGTGTGCATTTTAAGGAACCTCTCGTACCGGCTGGCGGC
AGAAACGTCTCAGGGACAGCACATGGGCACGGACGAGCTGGACGGGCTACTCTGTGGCGAGGCCAATGGCAAGGATGCTGAGAGCTCTGG
GTGCTGGGGCAAGAAGAAGAAGAAAAAGAAATCCCAAGATCAGTGGGATGGAGTAGGACCTCTTCCAGACTGTGCTGAACCACCAAAAGG
GATCCAGATGCTGTGGCACCCATCAATAGTCAAACCCTACCTCACACTGCTCTCTGAGTGCTCAAATCCAGACACGCTGGAAGGGGCGGC
AGGCGCCCTGCAGAACTTGGCTGCAGGGAGCTGGAAGTGGTCAGTATATATCCGAGCCGCTGTCCGAAAAGAGAAAGGCCTGCCCATCCT
CGTGGAGCTGCTCCGAATAGACAATGACCGTGTGGTGTGCGCGGTGGCCACTGCGCTGCGGAACATGGCCTTGGACGTCAGAAATAAGGA
GCTCATCGGGTGGAGGGTCCGGGGAGGAGCAACTCTATGCTGACTTTCCAGAACTTGACCTCTCCCAGCTGGATGCCAGCGACTTTGACT
CGGCCACCTGCTTTGGGGAGCTGCAGTGGTGCCCAGAGAACTCAGAGACTGAACCCAACCAGTACAGCCCCGATGACTCCGAGCTCTTCC
AGATTGACAGTGAGAATGAGGCCCTCCTGGCAGAGCTCACCAAGACCCTGGATGACATCCCTGAAGATGACGTGGGTCTGGCTGCCTTCC
CAGCCCTGGATGGTGGAGACGCTCTATCATGCACCTCAGCTTCGCCTGCCCCCTCATCTGCACCCCCCAGCCCTGCCCCGGAGAAGCCCT
CGGCCCCAGCCCCTGAGGTGGACGAGCTCTCACTGCTGCAGAAGCTCCTCCTGGCCACATCCTACCCAACATCAAGCTCTGACACCCAGA
AGGAAGGGACCGCCTGGCGCCAGGCAGGCCTCAGATCTAAAAGTCAACGGCCTTGTGTTAAGGCGGACAGCACCCAAGACAAGAAGGCTC
CCATGATGCAGTCTCAGAGCCGAAGTTGTACAGAACTACATAAGCACCTCACCTCGGCACAGTGCTGCCTGCAGGATCGGGGTCTGCAGC
CACCATGCCTCCAGAGTCCCCGGCTCCCTGCCAAGGAGGACAAGGAGCCGGGTGAGGACTGCCCGAGCCCCCAGCCAGCTCCAGCCTCTC
CCCGGGACTCCCTAGCTCTGGGCAGGGCAGACCCCGGTGCCCCGGTTTCCCAGGAAGACATGCAGGCGATGGTGCAACTCATACGCTACA
TGCACACCTACTGCCTCCCCCAGAGGAAGCTGCCCCCACAGACCCCTGAGCCACTCCCCAAGGCCTGCAGCAACCCCTCCCAGCAGGTCA
GATCCCGGCCCTGGTCCCGGCACCACTCCAAAGCCTCCTGGGCTGAGTTCTCCATTCTGAGGGAACTTCTGGCTCAAGACGTGCTCTGTG
ATGTCAGCAAACCCTACCGTCTGGCCACGCCTGTTTATGCCTCCCTCACACCTCGGTCAAGGCCCAGGCCCCCCAAAGACAGTCAGGCCT
CCCCTGGTCGCCCGTCCTCGGTGGAGGAGGTAAGGATCGCAGCTTCACCCAAGAGCACCGGGCCCAGACCAAGCCTGCGCCCACTGCGGC
TGGAGGTGAAAAGGGAGGTCCGCCGGCCTGCCAGACTGCAGCAGCAGGAGGAGGAAGACGAGGAAGAAGAGGAGGAGGAAGAGGAAGAAG
AAAAAGAGGAGGAGGAGGAGTGGGGCAGGAAAAGGCCAGGCCGAGGCCTGCCATGGACGAAGCTGGGGAGGAAGCTGGAGAGCTCTGTGT
GCCCCGTGCGGCGTTCTCGGAGACTGAACCCTGAGCTGGGCCCCTGGCTGACATTTGCAGATGAGCCGCTGGTCCCCTCGGAGCCCCAAG
GTGCTCTGCCCTCACTGTGCCTGGCTCCCAAGGCCTACGACGTAGAGCGGGAGCTGGGCAGCCCCACGGACGAGGACAGTGGCCAAGACC
AGCAGCTCCTACGGGGACCCCAGATCCCTGCCCTGGAGAGCCCCTGTGAGAGTGGGTGTGGGGACATGGATGAGGACCCCAGCTGCCCGC
AGCTCCCTCCCAGAGACTCTCCCAGGTGCCTCATGCTGGCCTTGTCACAAAGCGACCCAACTTTTGGCAAGAAGAGCTTTGAGCAGACCT
TGACAGTGGAGCTCTGTGGCACAGCAGGACTCACCCCACCCACCACACCACCGTACAAGCCCACAGAGGAGGATCCCTTCAAACCAGACA
TCAAGCATAGTCTAGGCAAAGAAATAGCTCTCAGCCTCCCCTCCCCTGAGGGCCTCTCACTCAAGGCCACCCCAGGGGCTGCCCACAAGC
TGCCAAAGAAGCACCCAGAGCGAAGTGAGCTCCTGTCCCACCTGCGACATGCCACAGCCCAGCCAGCCTCCCAGGCTGGCCAGAAGCGTC
CCTTCTCCTGTTCCTTTGGAGACCATGACTACTGCCAGGTGCTCCGACCAGAAGGCGTCCTGCAAAGGAAGGTGCTGAGGTCCTGGGAGC
CGTCTGGGGTTCACCTTGAGGACTGGCCCCAGCAGGGTGCCCCTTGGGCTGAGGCACAGGCCCCTGGCAGGGAGGAAGACAGAAGCTGTG
ATGCTGGCGCCCCACCCAAGGACAGCACGCTGCTGAGAGACCATGAGATCCGTGCCAGCCTCACCAAACACTTTGGGCTGCTGGAGACCG
CCCTGGAGGAGGAAGACCTGGCCTCCTGCAAGAGCCCTGAGTATGACACTGTCTTTGAAGACAGCAGCAGCAGCAGCGGCGAGAGCAGCT
TCCTCCCAGAGGAGGAAGAGGAAGAAGGGGAGGAGGAGGAGGAGGACGATGAAGAAGAGGACTCAGGGGTCAGCCCCACTTGCTCTGACC
ACTGCCCCTACCAGAGCCCACCAAGCAAGGCCAACCGGCAGCTCTGTTCCCGCAGCCGCTCAAGCTCTGGCTCTTCACCCTGCCACTCCT
GGTCACCAGCCACTCGAAGGAACTTCAGATGTGAGAGCAGAGGGCCGTGTTCAGACAGAACGCCAAGCATCCGGCACGCCAGGAAGCGGC
GGGAAAAGGCCATTGGGGAAGGCCGCGTGGTGTACATTCAAAATCTCTCCAGCGACATGAGCTCCCGAGAGCTGAAGAGGCGCTTTGAAG
TGTTTGGTGAGATTGAGGAGTGCGAGGTGCTGACAAGAAATAGGAGAGGCGAGAAGTACGGCTTCATCACCTACCGGTGTTCTGAGCACG
CGGCCCTCTCTTTGACAAAGGGCGCTGCCCTGAGGAAGCGCAACGAGCCCTCCTTCCAGCTGAGCTACGGAGGGCTCCGGCACTTCTGCT
GGCCCAGATACACTGACTACGGTAAGCCCCTGAAACCCAGCCACAGTCTAGTAAGACTCAAAGCTTGGGAAGCAGTGCCTTCCTTGAACA
AAACCCAGAGCTAAAGCGCCTTGTGGACATAGCTTCCATCCCCACACCCCAGTGTGCTGCTTGGTATAACTTTGCAGCCACTTTGCCTGA
AGACTACCATCCTGTTTCTCTTCTGGCCTCTGGTCCACCTTATCCTGTCCTGTGACTGCTACCAAAGAGAATCCAGCCTCCCACGGCCTC
TAGGAAGATTCAGTCATGTGCACAGCCAGCTGGCAGAACCGTGGCTACGGTCTCCTTGACTTCACAGGGCCAGCTGCTACCCTGTCCCCT
TCAGGGGCATTCCGTGGTGACCCCAGACAAGGCAGCAGCCACCTGGGGACAAGATGATGAAGAAGGACAAAGAAGTACAATGTACGAAAG
AATTACTTGGCCAGGCTCAGTGGCTCATGCCTGTAATCCCATCACCTTGGGAGGCTGAGGCAAGAGGATCACTTGAGCCCAGGAGTTCGA
GACCAGCTTGGGCAACATAGTGAAATCCTGTCTCTACAAAAAATATAAAAATTAGCCAGGCATGGTGGCTTGCGCCTATAGTCCCAGCTA
CTCAGGAGGCAGAGGTGGGAGGATCACCTGAACCCAAGAGGTTGGAGCTGCAGTGAGCCATGATGGCACTACTGCATTCCAGCCTGGGCA
ACAGAGCAAGACCCTGTCTCAAAAGGAAAGAAAAAAAAAAAAACACTTACTGGAGAGAATCCAATGCAGCCTTGATGGTACAGGACTGAG
TGTCAGTGACCCGGCTGGGTGCCAGGCCAGGCGGCCCTGCCCTTGGCTGCATGTCCATTTATGGGAATCAGTTTCCCAATCTATTAAAAA
ATTCTAGTGTTGGCTGGGTGCAGTTGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGAAGATCATGAGGTCAAGAGATCG
AGACCATCGTGGCCAACATGGTGAAACCCCCTCTCTATTAAAAATACAAAAATTAGCTGGGCGTGGTGGCGCACACCTGTAGTCCCAGCA
ACTTGGGAGGCTGAGGCGGGAGAATCACTTGAACCCGAGAGGCAGAGGTTGCAGTGAGCTGAGATCACATCCCTGCACTCCAGCCTTGGT
GACAGAGCGAGACTGCATCTCAAAAAAAAAAAAATTCTAGTGTTGTTAGCCCTCCCTTATGTGGCACTGCAGCAGGTTACTAATGGACGA
GAAGCTGTTGGGGGAAGTAGAGTTGTAGGGTGTTGGAGCTAGAAAGGCTCTGGAGTGCTCTAGTTTGGGCCTCCAGGTCTCTAGATAGGA
CAGCCAAGGCCCTGAGACACTGATACCATGGCCAAGATGTCCCAGCAGGATGGCAGGCAGTGCCCACAGTCCAGCGCTCATCCCAGCTCC
CCAAGGCCTTGGGCTGCAGCCACTCCACGGTGCCCACTCATAGTGGCAGATTCTTCAACCATCCGGTCTTTGTAAGTTGCTCACTGCCTT
CCCCTCTTCCCTGCCTCTTCACCCCCATGCCCAGATTCCAATTCAGAAGAGGCCCTTCCTGCGTCAGGGAAAAGCAAGTATGAAGCCATG
GATTTTGACAGCTTACTGAAAGAGGCCCAGCAGAGCCTGCATTGATAACAGCCTTAACCCTCGAGGAATACCTCAATACCTCAGACAAGG
CCCTTCCAATATGTTTACGTTTTCAAAGAAATCAAGTATATGAGGAGAGCGAGCGAGCGTGAGAGAACACCCGTGAGAGAGACTTGAAAC

>20399_20399_6_CTNND2-PPARGC1B_CTNND2_chr5_11082808_ENST00000511377_PPARGC1B_chr5_149199996_ENST00000394320_length(amino acids)=1016AA_BP=25
MTVWCARWPLRCGTWPWTSEIRSSSGGGSGEEQLYADFPELDLSQLDASDFDSATCFGELQWCPENSETEPNQYSPDDSELFQIDSENEA
LLAELTKTLDDIPEDDVGLAAFPALDGGDALSCTSASPAPSSAPPSPAPEKPSAPAPEVDELSLLQKLLLATSYPTSSSDTQKEGTAWRQ
AGLRSKSQRPCVKADSTQDKKAPMMQSQSRSCTELHKHLTSAQCCLQDRGLQPPCLQSPRLPAKEDKEPGEDCPSPQPAPASPRDSLALG
RADPGAPVSQEDMQAMVQLIRYMHTYCLPQRKLPPQTPEPLPKACSNPSQQVRSRPWSRHHSKASWAEFSILRELLAQDVLCDVSKPYRL
ATPVYASLTPRSRPRPPKDSQASPGRPSSVEEVRIAASPKSTGPRPSLRPLRLEVKREVRRPARLQQQEEEDEEEEEEEEEEEKEEEEEW
GRKRPGRGLPWTKLGRKLESSVCPVRRSRRLNPELGPWLTFADEPLVPSEPQGALPSLCLAPKAYDVERELGSPTDEDSGQDQQLLRGPQ
IPALESPCESGCGDMDEDPSCPQLPPRDSPRCLMLALSQSDPTFGKKSFEQTLTVELCGTAGLTPPTTPPYKPTEEDPFKPDIKHSLGKE
IALSLPSPEGLSLKATPGAAHKLPKKHPERSELLSHLRHATAQPASQAGQKRPFSCSFGDHDYCQVLRPEGVLQRKVLRSWEPSGVHLED
WPQQGAPWAEAQAPGREEDRSCDAGAPPKDSTLLRDHEIRASLTKHFGLLETALEEEDLASCKSPEYDTVFEDSSSSSGESSFLPEEEEE
EGEEEEEDDEEEDSGVSPTCSDHCPYQSPPSKANRQLCSRSRSSSGSSPCHSWSPATRRNFRCESRGPCSDRTPSIRHARKRREKAIGEG
RVVYIQNLSSDMSSRELKRRFEVFGEIEECEVLTRNRRGEKYGFITYRCSEHAALSLTKGAALRKRNEPSFQLSYGGLRHFCWPRYTDYG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CTNND2-PPARGC1B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CTNND2-PPARGC1B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CTNND2-PPARGC1B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCTNND2C0007621Neoplastic Cell Transformation1CTD_human
HgeneCTNND2C0017636Glioblastoma1CTD_human
HgeneCTNND2C0036341Schizophrenia1PSYGENET
HgeneCTNND2C0041696Unipolar Depression1PSYGENET
HgeneCTNND2C0334588Giant Cell Glioblastoma1CTD_human
HgeneCTNND2C1269683Major Depressive Disorder1PSYGENET
HgeneCTNND2C1621958Glioblastoma Multiforme1CTD_human
HgeneCTNND2C1832841EPILEPSY, FAMILIAL ADULT MYOCLONIC, 11ORPHANET
HgeneCTNND2C3495676Anorectal Malformations1GENOMICS_ENGLAND
TgeneC0006142Malignant neoplasm of breast1CTD_human
TgeneC0020473Hyperlipidemia1CTD_human
TgeneC0028754Obesity1CTD_human
TgeneC0678222Breast Carcinoma1CTD_human
TgeneC1257931Mammary Neoplasms, Human1CTD_human
TgeneC1458155Mammary Neoplasms1CTD_human
TgeneC1706412Lipidemias1CTD_human
TgeneC4704874Mammary Carcinoma, Human1CTD_human