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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CTSB-TG (FusionGDB2 ID:HG1508TG7038)

Fusion Gene Summary for CTSB-TG

check button Fusion gene summary
Fusion gene informationFusion gene name: CTSB-TG
Fusion gene ID: hg1508tg7038
HgeneTgene
Gene symbol

CTSB

TG

Gene ID

1508

7038

Gene namecathepsin Bthyroglobulin
SynonymsAPPS|CPSB|RECEUPAITD3|TGN
Cytomap('CTSB')('TG')

8p23.1

8q24.22

Type of geneprotein-codingprotein-coding
Descriptioncathepsin BAPP secretaseamyloid precursor protein secretasecathepsin B1cysteine proteaseepididymis secretory sperm binding proteinthyroglobulin
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000415599, ENST00000345125, 
ENST00000353047, ENST00000434271, 
ENST00000453527, ENST00000530640, 
ENST00000531089, ENST00000533455, 
ENST00000534510, ENST00000525076, 
Fusion gene scores* DoF score24 X 19 X 10=456027 X 26 X 8=5616
# samples 2529
** MAII scorelog2(25/4560*10)=-4.18903382439002
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(29/5616*10)=-4.27541813028963
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CTSB [Title/Abstract] AND TG [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCTSB(11705575)-TG(134042125), # samples:1
CTSB(11705577)-TG(134042123), # samples:1
Anticipated loss of major functional domain due to fusion event.CTSB-TG seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CTSB-TG seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CTSB-TG seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCTSB

GO:0006508

proteolysis

7890620|8811434

HgeneCTSB

GO:0030574

collagen catabolic process

22952693

HgeneCTSB

GO:0051603

proteolysis involved in cellular protein catabolic process

22952693


check buttonFusion gene breakpoints across CTSB (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across TG (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerTCGA-EL-A3H1-11ACTSBchr8

11705577

-TGchr8

134042123

+
ChimerDB4Non-CancerTCGA-EL-A3TA-11ACTSBchr8

11705575

-TGchr8

134042125

+


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Fusion Gene ORF analysis for CTSB-TG

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000415599ENST00000220616CTSBchr8

11705577

-TGchr8

134042123

+
3UTR-3CDSENST00000415599ENST00000220616CTSBchr8

11705575

-TGchr8

134042125

+
3UTR-3CDSENST00000415599ENST00000377869CTSBchr8

11705577

-TGchr8

134042123

+
3UTR-3CDSENST00000415599ENST00000377869CTSBchr8

11705575

-TGchr8

134042125

+
3UTR-3CDSENST00000415599ENST00000519543CTSBchr8

11705577

-TGchr8

134042123

+
3UTR-3CDSENST00000415599ENST00000519543CTSBchr8

11705575

-TGchr8

134042125

+
3UTR-3CDSENST00000415599ENST00000542445CTSBchr8

11705577

-TGchr8

134042123

+
3UTR-3CDSENST00000415599ENST00000542445CTSBchr8

11705575

-TGchr8

134042125

+
3UTR-intronENST00000415599ENST00000522523CTSBchr8

11705577

-TGchr8

134042123

+
3UTR-intronENST00000415599ENST00000522523CTSBchr8

11705575

-TGchr8

134042125

+
5CDS-intronENST00000345125ENST00000522523CTSBchr8

11705577

-TGchr8

134042123

+
5CDS-intronENST00000345125ENST00000522523CTSBchr8

11705575

-TGchr8

134042125

+
5CDS-intronENST00000353047ENST00000522523CTSBchr8

11705577

-TGchr8

134042123

+
5CDS-intronENST00000353047ENST00000522523CTSBchr8

11705575

-TGchr8

134042125

+
5CDS-intronENST00000434271ENST00000522523CTSBchr8

11705577

-TGchr8

134042123

+
5CDS-intronENST00000434271ENST00000522523CTSBchr8

11705575

-TGchr8

134042125

+
5CDS-intronENST00000453527ENST00000522523CTSBchr8

11705577

-TGchr8

134042123

+
5CDS-intronENST00000453527ENST00000522523CTSBchr8

11705575

-TGchr8

134042125

+
5CDS-intronENST00000530640ENST00000522523CTSBchr8

11705577

-TGchr8

134042123

+
5CDS-intronENST00000530640ENST00000522523CTSBchr8

11705575

-TGchr8

134042125

+
5CDS-intronENST00000531089ENST00000522523CTSBchr8

11705577

-TGchr8

134042123

+
5CDS-intronENST00000531089ENST00000522523CTSBchr8

11705575

-TGchr8

134042125

+
5CDS-intronENST00000533455ENST00000522523CTSBchr8

11705577

-TGchr8

134042123

+
5CDS-intronENST00000533455ENST00000522523CTSBchr8

11705575

-TGchr8

134042125

+
5CDS-intronENST00000534510ENST00000522523CTSBchr8

11705577

-TGchr8

134042123

+
5CDS-intronENST00000534510ENST00000522523CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000345125ENST00000220616CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000345125ENST00000220616CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000345125ENST00000377869CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000345125ENST00000377869CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000345125ENST00000519543CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000345125ENST00000519543CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000345125ENST00000542445CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000345125ENST00000542445CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000353047ENST00000220616CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000353047ENST00000220616CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000353047ENST00000377869CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000353047ENST00000377869CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000353047ENST00000519543CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000353047ENST00000519543CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000353047ENST00000542445CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000353047ENST00000542445CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000453527ENST00000220616CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000453527ENST00000220616CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000453527ENST00000377869CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000453527ENST00000377869CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000453527ENST00000519543CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000453527ENST00000519543CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000453527ENST00000542445CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000453527ENST00000542445CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000531089ENST00000220616CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000531089ENST00000220616CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000531089ENST00000377869CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000531089ENST00000377869CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000531089ENST00000519543CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000531089ENST00000519543CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000531089ENST00000542445CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000531089ENST00000542445CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000534510ENST00000220616CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000534510ENST00000220616CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000534510ENST00000377869CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000534510ENST00000377869CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000534510ENST00000519543CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000534510ENST00000519543CTSBchr8

11705575

-TGchr8

134042125

+
Frame-shiftENST00000534510ENST00000542445CTSBchr8

11705577

-TGchr8

134042123

+
Frame-shiftENST00000534510ENST00000542445CTSBchr8

11705575

-TGchr8

134042125

+
In-frameENST00000434271ENST00000220616CTSBchr8

11705577

-TGchr8

134042123

+
In-frameENST00000434271ENST00000220616CTSBchr8

11705575

-TGchr8

134042125

+
In-frameENST00000434271ENST00000377869CTSBchr8

11705577

-TGchr8

134042123

+
In-frameENST00000434271ENST00000377869CTSBchr8

11705575

-TGchr8

134042125

+
In-frameENST00000434271ENST00000519543CTSBchr8

11705577

-TGchr8

134042123

+
In-frameENST00000434271ENST00000519543CTSBchr8

11705575

-TGchr8

134042125

+
In-frameENST00000434271ENST00000542445CTSBchr8

11705577

-TGchr8

134042123

+
In-frameENST00000434271ENST00000542445CTSBchr8

11705575

-TGchr8

134042125

+
In-frameENST00000530640ENST00000220616CTSBchr8

11705577

-TGchr8

134042123

+
In-frameENST00000530640ENST00000220616CTSBchr8

11705575

-TGchr8

134042125

+
In-frameENST00000530640ENST00000377869CTSBchr8

11705577

-TGchr8

134042123

+
In-frameENST00000530640ENST00000377869CTSBchr8

11705575

-TGchr8

134042125

+
In-frameENST00000530640ENST00000519543CTSBchr8

11705577

-TGchr8

134042123

+
In-frameENST00000530640ENST00000519543CTSBchr8

11705575

-TGchr8

134042125

+
In-frameENST00000530640ENST00000542445CTSBchr8

11705577

-TGchr8

134042123

+
In-frameENST00000530640ENST00000542445CTSBchr8

11705575

-TGchr8

134042125

+
In-frameENST00000533455ENST00000220616CTSBchr8

11705577

-TGchr8

134042123

+
In-frameENST00000533455ENST00000220616CTSBchr8

11705575

-TGchr8

134042125

+
In-frameENST00000533455ENST00000377869CTSBchr8

11705577

-TGchr8

134042123

+
In-frameENST00000533455ENST00000377869CTSBchr8

11705575

-TGchr8

134042125

+
In-frameENST00000533455ENST00000519543CTSBchr8

11705577

-TGchr8

134042123

+
In-frameENST00000533455ENST00000519543CTSBchr8

11705575

-TGchr8

134042125

+
In-frameENST00000533455ENST00000542445CTSBchr8

11705577

-TGchr8

134042123

+
In-frameENST00000533455ENST00000542445CTSBchr8

11705575

-TGchr8

134042125

+
intron-3CDSENST00000525076ENST00000220616CTSBchr8

11705577

-TGchr8

134042123

+
intron-3CDSENST00000525076ENST00000220616CTSBchr8

11705575

-TGchr8

134042125

+
intron-3CDSENST00000525076ENST00000377869CTSBchr8

11705577

-TGchr8

134042123

+
intron-3CDSENST00000525076ENST00000377869CTSBchr8

11705575

-TGchr8

134042125

+
intron-3CDSENST00000525076ENST00000519543CTSBchr8

11705577

-TGchr8

134042123

+
intron-3CDSENST00000525076ENST00000519543CTSBchr8

11705575

-TGchr8

134042125

+
intron-3CDSENST00000525076ENST00000542445CTSBchr8

11705577

-TGchr8

134042123

+
intron-3CDSENST00000525076ENST00000542445CTSBchr8

11705575

-TGchr8

134042125

+
intron-intronENST00000525076ENST00000522523CTSBchr8

11705577

-TGchr8

134042123

+
intron-intronENST00000525076ENST00000522523CTSBchr8

11705575

-TGchr8

134042125

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000434271CTSBchr811705575-ENST00000377869TGchr8134042125+20867702381980580
ENST00000434271CTSBchr811705575-ENST00000220616TGchr8134042125+20847702381980580
ENST00000434271CTSBchr811705575-ENST00000542445TGchr8134042125+20147702381980580
ENST00000434271CTSBchr811705575-ENST00000519543TGchr8134042125+20907702381980580
ENST00000530640CTSBchr811705575-ENST00000377869TGchr8134042125+19856691371879580
ENST00000530640CTSBchr811705575-ENST00000220616TGchr8134042125+19836691371879580
ENST00000530640CTSBchr811705575-ENST00000542445TGchr8134042125+19136691371879580
ENST00000530640CTSBchr811705575-ENST00000519543TGchr8134042125+19896691371879580
ENST00000533455CTSBchr811705575-ENST00000377869TGchr8134042125+20677512191961580
ENST00000533455CTSBchr811705575-ENST00000220616TGchr8134042125+20657512191961580
ENST00000533455CTSBchr811705575-ENST00000542445TGchr8134042125+19957512191961580
ENST00000533455CTSBchr811705575-ENST00000519543TGchr8134042125+20717512191961580
ENST00000434271CTSBchr811705577-ENST00000377869TGchr8134042123+20887708191982387
ENST00000434271CTSBchr811705577-ENST00000220616TGchr8134042123+20867708191982387
ENST00000434271CTSBchr811705577-ENST00000542445TGchr8134042123+20167708191982387
ENST00000434271CTSBchr811705577-ENST00000519543TGchr8134042123+20927708191982387
ENST00000530640CTSBchr811705577-ENST00000377869TGchr8134042123+19876697181881387
ENST00000530640CTSBchr811705577-ENST00000220616TGchr8134042123+19856697181881387
ENST00000530640CTSBchr811705577-ENST00000542445TGchr8134042123+19156697181881387
ENST00000530640CTSBchr811705577-ENST00000519543TGchr8134042123+19916697181881387
ENST00000533455CTSBchr811705577-ENST00000377869TGchr8134042123+20697518001963387
ENST00000533455CTSBchr811705577-ENST00000220616TGchr8134042123+20677518001963387
ENST00000533455CTSBchr811705577-ENST00000542445TGchr8134042123+19977518001963387
ENST00000533455CTSBchr811705577-ENST00000519543TGchr8134042123+20737518001963387

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000434271ENST00000377869CTSBchr811705575-TGchr8134042125+0.0170314540.9829685
ENST00000434271ENST00000220616CTSBchr811705575-TGchr8134042125+0.0168229120.9831771
ENST00000434271ENST00000542445CTSBchr811705575-TGchr8134042125+0.0187411230.9812588
ENST00000434271ENST00000519543CTSBchr811705575-TGchr8134042125+0.0177929030.98220706
ENST00000530640ENST00000377869CTSBchr811705575-TGchr8134042125+0.0216038920.9783961
ENST00000530640ENST00000220616CTSBchr811705575-TGchr8134042125+0.021409660.97859037
ENST00000530640ENST00000542445CTSBchr811705575-TGchr8134042125+0.0233076440.97669244
ENST00000530640ENST00000519543CTSBchr811705575-TGchr8134042125+0.0219891540.97801083
ENST00000533455ENST00000377869CTSBchr811705575-TGchr8134042125+0.0208676330.97913235
ENST00000533455ENST00000220616CTSBchr811705575-TGchr8134042125+0.0206716360.97932833
ENST00000533455ENST00000542445CTSBchr811705575-TGchr8134042125+0.0227362590.97726375
ENST00000533455ENST00000519543CTSBchr811705575-TGchr8134042125+0.0215380640.978462
ENST00000434271ENST00000377869CTSBchr811705577-TGchr8134042123+0.0159486120.9840514
ENST00000434271ENST00000220616CTSBchr811705577-TGchr8134042123+0.0159415640.98405844
ENST00000434271ENST00000542445CTSBchr811705577-TGchr8134042123+0.0160439850.98395604
ENST00000434271ENST00000519543CTSBchr811705577-TGchr8134042123+0.0158959660.98410404
ENST00000530640ENST00000377869CTSBchr811705577-TGchr8134042123+0.0159923290.98400766
ENST00000530640ENST00000220616CTSBchr811705577-TGchr8134042123+0.0160826170.98391736
ENST00000530640ENST00000542445CTSBchr811705577-TGchr8134042123+0.0157477280.9842523
ENST00000530640ENST00000519543CTSBchr811705577-TGchr8134042123+0.0154835140.98451644
ENST00000533455ENST00000377869CTSBchr811705577-TGchr8134042123+0.0174798780.98252004
ENST00000533455ENST00000220616CTSBchr811705577-TGchr8134042123+0.0174990610.982501
ENST00000533455ENST00000542445CTSBchr811705577-TGchr8134042123+0.0173023250.98269767
ENST00000533455ENST00000519543CTSBchr811705577-TGchr8134042123+0.0171465630.9828535

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Fusion Genomic Features for CTSB-TG


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for CTSB-TG


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:11705575/chr8:134042125)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

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* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTGchr8:11705575chr8:134042125ENST000002206160481074_114502769.0DomainThyroglobulin type-1 9
TgeneTGchr8:11705575chr8:134042125ENST000002206160481146_121002769.0DomainThyroglobulin type-1 10
TgeneTGchr8:11705575chr8:134042125ENST000002206160481511_156502769.0DomainThyroglobulin type-1 11
TgeneTGchr8:11705575chr8:134042125ENST00000220616048161_29702769.0DomainThyroglobulin type-1 3
TgeneTGchr8:11705575chr8:134042125ENST00000220616048298_35802769.0DomainThyroglobulin type-1 4
TgeneTGchr8:11705575chr8:134042125ENST0000022061604831_9202769.0DomainThyroglobulin type-1 1
TgeneTGchr8:11705575chr8:134042125ENST00000220616048605_65802769.0DomainThyroglobulin type-1 5
TgeneTGchr8:11705575chr8:134042125ENST00000220616048659_72602769.0DomainThyroglobulin type-1 6
TgeneTGchr8:11705575chr8:134042125ENST00000220616048727_92102769.0DomainThyroglobulin type-1 7
TgeneTGchr8:11705575chr8:134042125ENST00000220616048922_107302769.0DomainThyroglobulin type-1 8
TgeneTGchr8:11705575chr8:134042125ENST0000022061604893_16002769.0DomainThyroglobulin type-1 2
TgeneTGchr8:11705575chr8:134042125ENST000003778690471074_114502712.0DomainThyroglobulin type-1 9
TgeneTGchr8:11705575chr8:134042125ENST000003778690471146_121002712.0DomainThyroglobulin type-1 10
TgeneTGchr8:11705575chr8:134042125ENST000003778690471511_156502712.0DomainThyroglobulin type-1 11
TgeneTGchr8:11705575chr8:134042125ENST00000377869047161_29702712.0DomainThyroglobulin type-1 3
TgeneTGchr8:11705575chr8:134042125ENST00000377869047298_35802712.0DomainThyroglobulin type-1 4
TgeneTGchr8:11705575chr8:134042125ENST0000037786904731_9202712.0DomainThyroglobulin type-1 1
TgeneTGchr8:11705575chr8:134042125ENST00000377869047605_65802712.0DomainThyroglobulin type-1 5
TgeneTGchr8:11705575chr8:134042125ENST00000377869047659_72602712.0DomainThyroglobulin type-1 6
TgeneTGchr8:11705575chr8:134042125ENST00000377869047727_92102712.0DomainThyroglobulin type-1 7
TgeneTGchr8:11705575chr8:134042125ENST00000377869047922_107302712.0DomainThyroglobulin type-1 8
TgeneTGchr8:11705575chr8:134042125ENST0000037786904793_16002712.0DomainThyroglobulin type-1 2
TgeneTGchr8:11705577chr8:134042123ENST000002206160481074_114502769.0DomainThyroglobulin type-1 9
TgeneTGchr8:11705577chr8:134042123ENST000002206160481146_121002769.0DomainThyroglobulin type-1 10
TgeneTGchr8:11705577chr8:134042123ENST000002206160481511_156502769.0DomainThyroglobulin type-1 11
TgeneTGchr8:11705577chr8:134042123ENST00000220616048161_29702769.0DomainThyroglobulin type-1 3
TgeneTGchr8:11705577chr8:134042123ENST00000220616048298_35802769.0DomainThyroglobulin type-1 4
TgeneTGchr8:11705577chr8:134042123ENST0000022061604831_9202769.0DomainThyroglobulin type-1 1
TgeneTGchr8:11705577chr8:134042123ENST00000220616048605_65802769.0DomainThyroglobulin type-1 5
TgeneTGchr8:11705577chr8:134042123ENST00000220616048659_72602769.0DomainThyroglobulin type-1 6
TgeneTGchr8:11705577chr8:134042123ENST00000220616048727_92102769.0DomainThyroglobulin type-1 7
TgeneTGchr8:11705577chr8:134042123ENST00000220616048922_107302769.0DomainThyroglobulin type-1 8
TgeneTGchr8:11705577chr8:134042123ENST0000022061604893_16002769.0DomainThyroglobulin type-1 2
TgeneTGchr8:11705577chr8:134042123ENST000003778690471074_114502712.0DomainThyroglobulin type-1 9
TgeneTGchr8:11705577chr8:134042123ENST000003778690471146_121002712.0DomainThyroglobulin type-1 10
TgeneTGchr8:11705577chr8:134042123ENST000003778690471511_156502712.0DomainThyroglobulin type-1 11
TgeneTGchr8:11705577chr8:134042123ENST00000377869047161_29702712.0DomainThyroglobulin type-1 3
TgeneTGchr8:11705577chr8:134042123ENST00000377869047298_35802712.0DomainThyroglobulin type-1 4
TgeneTGchr8:11705577chr8:134042123ENST0000037786904731_9202712.0DomainThyroglobulin type-1 1
TgeneTGchr8:11705577chr8:134042123ENST00000377869047605_65802712.0DomainThyroglobulin type-1 5
TgeneTGchr8:11705577chr8:134042123ENST00000377869047659_72602712.0DomainThyroglobulin type-1 6
TgeneTGchr8:11705577chr8:134042123ENST00000377869047727_92102712.0DomainThyroglobulin type-1 7
TgeneTGchr8:11705577chr8:134042123ENST00000377869047922_107302712.0DomainThyroglobulin type-1 8
TgeneTGchr8:11705577chr8:134042123ENST0000037786904793_16002712.0DomainThyroglobulin type-1 2
TgeneTGchr8:11705575chr8:134042125ENST000002206160482188_276802769.0RegionCholinesterase-like (ChEL)
TgeneTGchr8:11705575chr8:134042125ENST000003778690472188_276802712.0RegionCholinesterase-like (ChEL)
TgeneTGchr8:11705577chr8:134042123ENST000002206160482188_276802769.0RegionCholinesterase-like (ChEL)
TgeneTGchr8:11705577chr8:134042123ENST000003778690472188_276802712.0RegionCholinesterase-like (ChEL)
TgeneTGchr8:11705575chr8:134042125ENST000002206160481456_146902769.0RepeatType II
TgeneTGchr8:11705575chr8:134042125ENST000002206160481470_148602769.0RepeatType II
TgeneTGchr8:11705575chr8:134042125ENST000002206160481487_150302769.0RepeatType II
TgeneTGchr8:11705575chr8:134042125ENST000002206160481603_172302769.0RepeatType IIIA
TgeneTGchr8:11705575chr8:134042125ENST000002206160481724_189202769.0RepeatType IIIB
TgeneTGchr8:11705575chr8:134042125ENST000002206160481893_199502769.0RepeatType IIIA
TgeneTGchr8:11705575chr8:134042125ENST000002206160481996_212902769.0RepeatType IIIB
TgeneTGchr8:11705575chr8:134042125ENST000002206160482130_218702769.0RepeatType IIIA
TgeneTGchr8:11705575chr8:134042125ENST000003778690471456_146902712.0RepeatType II
TgeneTGchr8:11705575chr8:134042125ENST000003778690471470_148602712.0RepeatType II
TgeneTGchr8:11705575chr8:134042125ENST000003778690471487_150302712.0RepeatType II
TgeneTGchr8:11705575chr8:134042125ENST000003778690471603_172302712.0RepeatType IIIA
TgeneTGchr8:11705575chr8:134042125ENST000003778690471724_189202712.0RepeatType IIIB
TgeneTGchr8:11705575chr8:134042125ENST000003778690471893_199502712.0RepeatType IIIA
TgeneTGchr8:11705575chr8:134042125ENST000003778690471996_212902712.0RepeatType IIIB
TgeneTGchr8:11705575chr8:134042125ENST000003778690472130_218702712.0RepeatType IIIA
TgeneTGchr8:11705577chr8:134042123ENST000002206160481456_146902769.0RepeatType II
TgeneTGchr8:11705577chr8:134042123ENST000002206160481470_148602769.0RepeatType II
TgeneTGchr8:11705577chr8:134042123ENST000002206160481487_150302769.0RepeatType II
TgeneTGchr8:11705577chr8:134042123ENST000002206160481603_172302769.0RepeatType IIIA
TgeneTGchr8:11705577chr8:134042123ENST000002206160481724_189202769.0RepeatType IIIB
TgeneTGchr8:11705577chr8:134042123ENST000002206160481893_199502769.0RepeatType IIIA
TgeneTGchr8:11705577chr8:134042123ENST000002206160481996_212902769.0RepeatType IIIB
TgeneTGchr8:11705577chr8:134042123ENST000002206160482130_218702769.0RepeatType IIIA
TgeneTGchr8:11705577chr8:134042123ENST000003778690471456_146902712.0RepeatType II
TgeneTGchr8:11705577chr8:134042123ENST000003778690471470_148602712.0RepeatType II
TgeneTGchr8:11705577chr8:134042123ENST000003778690471487_150302712.0RepeatType II
TgeneTGchr8:11705577chr8:134042123ENST000003778690471603_172302712.0RepeatType IIIA
TgeneTGchr8:11705577chr8:134042123ENST000003778690471724_189202712.0RepeatType IIIB
TgeneTGchr8:11705577chr8:134042123ENST000003778690471893_199502712.0RepeatType IIIA
TgeneTGchr8:11705577chr8:134042123ENST000003778690471996_212902712.0RepeatType IIIB
TgeneTGchr8:11705577chr8:134042123ENST000003778690472130_218702712.0RepeatType IIIA

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for CTSB-TG


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>20477_20477_1_CTSB-TG_CTSB_chr8_11705575_ENST00000434271_TG_chr8_134042125_ENST00000220616_length(transcript)=2084nt_BP=770nt
GGGGCGGGGCCGGGAGGGTACTTAGGGCCGGGGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCG
CTCCGCTGCGCGCAGGCTGGGCTGCAGGCTCTCGGCTGCAGCGCTGGGTGAGTGCTGGGGACCCGGGGCCACCGCAGCGTAAGTGACCCA
GAGAGGTGTCCTGATGCCCTCTGTCCTCTCCAGGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCT
GCTGGTGTTGGCCAATGCCCGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTG
GCAGGCCGGGCACAACTTCTACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAG
AGTTATGTTTACCGAGGACCTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGA
CCAGGGCTCCTGTGGCTCCTGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGT
GGAGGTGTCGGCGGAGGACCTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTT
CTGGACAAGAAAAGGCCTGGTTTCTGGTGGCCTCTATGAATCCCATGTAGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCG
CGTGTCCCTGGCAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAG
AGCTGTGCTGATGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGA
GGTCAGTTGCCCCATGTCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCT
CCTGGCCGTGAGTGGCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTC
TTTATGGGTAGAGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAG
TCGAGGCCGGACCAGTAGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGC
TGCTACATGGTATTACTCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTAT
CATCTGCCCTATAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCA
TGGCAGCCTGGAGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAA
GAGCCTGTCGCTGAAAATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACC
CACATTTGCAACCCCCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGG
CCTGAAGAAAGCCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGA
GAGTGAAGAGGAGGAGTTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTG
ACCAGCCCTTGAGCTCCCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGT
ATCTACATGCGGTG

>20477_20477_1_CTSB-TG_CTSB_chr8_11705575_ENST00000434271_TG_chr8_134042125_ENST00000220616_length(amino acids)=580AA_BP=177
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQW
PQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVVQT
HIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKP
ANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLG
GEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYP
AYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTS
ADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_2_CTSB-TG_CTSB_chr8_11705575_ENST00000434271_TG_chr8_134042125_ENST00000377869_length(transcript)=2086nt_BP=770nt
GGGGCGGGGCCGGGAGGGTACTTAGGGCCGGGGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCG
CTCCGCTGCGCGCAGGCTGGGCTGCAGGCTCTCGGCTGCAGCGCTGGGTGAGTGCTGGGGACCCGGGGCCACCGCAGCGTAAGTGACCCA
GAGAGGTGTCCTGATGCCCTCTGTCCTCTCCAGGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCT
GCTGGTGTTGGCCAATGCCCGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTG
GCAGGCCGGGCACAACTTCTACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAG
AGTTATGTTTACCGAGGACCTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGA
CCAGGGCTCCTGTGGCTCCTGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGT
GGAGGTGTCGGCGGAGGACCTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTT
CTGGACAAGAAAAGGCCTGGTTTCTGGTGGCCTCTATGAATCCCATGTAGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCG
CGTGTCCCTGGCAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAG
AGCTGTGCTGATGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGA
GGTCAGTTGCCCCATGTCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCT
CCTGGCCGTGAGTGGCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTC
TTTATGGGTAGAGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAG
TCGAGGCCGGACCAGTAGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGC
TGCTACATGGTATTACTCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTAT
CATCTGCCCTATAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCA
TGGCAGCCTGGAGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAA
GAGCCTGTCGCTGAAAATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACC
CACATTTGCAACCCCCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGG
CCTGAAGAAAGCCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGA
GAGTGAAGAGGAGGAGTTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTG
ACCAGCCCTTGAGCTCCCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGT
ATCTACATGCGGTGAA

>20477_20477_2_CTSB-TG_CTSB_chr8_11705575_ENST00000434271_TG_chr8_134042125_ENST00000377869_length(amino acids)=580AA_BP=177
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQW
PQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVVQT
HIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKP
ANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLG
GEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYP
AYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTS
ADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_3_CTSB-TG_CTSB_chr8_11705575_ENST00000434271_TG_chr8_134042125_ENST00000519543_length(transcript)=2090nt_BP=770nt
GGGGCGGGGCCGGGAGGGTACTTAGGGCCGGGGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCG
CTCCGCTGCGCGCAGGCTGGGCTGCAGGCTCTCGGCTGCAGCGCTGGGTGAGTGCTGGGGACCCGGGGCCACCGCAGCGTAAGTGACCCA
GAGAGGTGTCCTGATGCCCTCTGTCCTCTCCAGGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCT
GCTGGTGTTGGCCAATGCCCGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTG
GCAGGCCGGGCACAACTTCTACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAG
AGTTATGTTTACCGAGGACCTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGA
CCAGGGCTCCTGTGGCTCCTGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGT
GGAGGTGTCGGCGGAGGACCTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTT
CTGGACAAGAAAAGGCCTGGTTTCTGGTGGCCTCTATGAATCCCATGTAGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCG
CGTGTCCCTGGCAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAG
AGCTGTGCTGATGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGA
GGTCAGTTGCCCCATGTCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCT
CCTGGCCGTGAGTGGCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTC
TTTATGGGTAGAGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAG
TCGAGGCCGGACCAGTAGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGC
TGCTACATGGTATTACTCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTAT
CATCTGCCCTATAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCA
TGGCAGCCTGGAGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAA
GAGCCTGTCGCTGAAAATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACC
CACATTTGCAACCCCCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGG
CCTGAAGAAAGCCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGA
GAGTGAAGAGGAGGAGTTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTG
ACCAGCCCTTGAGCTCCCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGT
ATCTACATGCGGTGAAGCAT

>20477_20477_3_CTSB-TG_CTSB_chr8_11705575_ENST00000434271_TG_chr8_134042125_ENST00000519543_length(amino acids)=580AA_BP=177
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQW
PQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVVQT
HIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKP
ANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLG
GEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYP
AYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTS
ADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_4_CTSB-TG_CTSB_chr8_11705575_ENST00000434271_TG_chr8_134042125_ENST00000542445_length(transcript)=2014nt_BP=770nt
GGGGCGGGGCCGGGAGGGTACTTAGGGCCGGGGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCG
CTCCGCTGCGCGCAGGCTGGGCTGCAGGCTCTCGGCTGCAGCGCTGGGTGAGTGCTGGGGACCCGGGGCCACCGCAGCGTAAGTGACCCA
GAGAGGTGTCCTGATGCCCTCTGTCCTCTCCAGGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCT
GCTGGTGTTGGCCAATGCCCGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTG
GCAGGCCGGGCACAACTTCTACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAG
AGTTATGTTTACCGAGGACCTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGA
CCAGGGCTCCTGTGGCTCCTGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGT
GGAGGTGTCGGCGGAGGACCTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTT
CTGGACAAGAAAAGGCCTGGTTTCTGGTGGCCTCTATGAATCCCATGTAGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCG
CGTGTCCCTGGCAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAG
AGCTGTGCTGATGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGA
GGTCAGTTGCCCCATGTCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCT
CCTGGCCGTGAGTGGCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTC
TTTATGGGTAGAGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAG
TCGAGGCCGGACCAGTAGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGC
TGCTACATGGTATTACTCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTAT
CATCTGCCCTATAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCA
TGGCAGCCTGGAGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAA
GAGCCTGTCGCTGAAAATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACC
CACATTTGCAACCCCCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGG
CCTGAAGAAAGCCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGA
GAGTGAAGAGGAGGAGTTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTG
ACCAGCCCTTGAGCTCCCCAAAAACCTCACCCGA

>20477_20477_4_CTSB-TG_CTSB_chr8_11705575_ENST00000434271_TG_chr8_134042125_ENST00000542445_length(amino acids)=580AA_BP=177
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQW
PQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVVQT
HIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKP
ANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLG
GEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYP
AYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTS
ADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_5_CTSB-TG_CTSB_chr8_11705575_ENST00000530640_TG_chr8_134042125_ENST00000220616_length(transcript)=1983nt_BP=669nt
GGCCGGGGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCGCTCCGCTGCGCGCAGGCTGGGCTGC
AGGCTCTCGGCTGCAGCGCTGGGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCTGCTGGTGTTGG
CCAATGCCCGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTGGCAGGCCGGGC
ACAACTTCTACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAGAGTTATGTTTA
CCGAGGACCTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGACCAGGGCTCCT
GTGGCTCCTGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGTGGAGGTGTCGG
CGGAGGACCTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTTCTGGACAAGAA
AAGGCCTGGTTTCTGGTGGCCTCTATGAATCCCATGTAGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGG
CAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGA
TGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCC
CCATGTCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGA
GTGGCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAG
AGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGA
CCAGTAGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGT
ATTACTCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTA
TAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGG
AGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGC
TGAAAATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAA
CCCCCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAG
CCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGG
AGGAGTTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTG
AGCTCCCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATGCG
GTG

>20477_20477_5_CTSB-TG_CTSB_chr8_11705575_ENST00000530640_TG_chr8_134042125_ENST00000220616_length(amino acids)=580AA_BP=177
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQW
PQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVVQT
HIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKP
ANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLG
GEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYP
AYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTS
ADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_6_CTSB-TG_CTSB_chr8_11705575_ENST00000530640_TG_chr8_134042125_ENST00000377869_length(transcript)=1985nt_BP=669nt
GGCCGGGGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCGCTCCGCTGCGCGCAGGCTGGGCTGC
AGGCTCTCGGCTGCAGCGCTGGGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCTGCTGGTGTTGG
CCAATGCCCGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTGGCAGGCCGGGC
ACAACTTCTACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAGAGTTATGTTTA
CCGAGGACCTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGACCAGGGCTCCT
GTGGCTCCTGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGTGGAGGTGTCGG
CGGAGGACCTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTTCTGGACAAGAA
AAGGCCTGGTTTCTGGTGGCCTCTATGAATCCCATGTAGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGG
CAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGA
TGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCC
CCATGTCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGA
GTGGCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAG
AGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGA
CCAGTAGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGT
ATTACTCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTA
TAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGG
AGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGC
TGAAAATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAA
CCCCCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAG
CCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGG
AGGAGTTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTG
AGCTCCCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATGCG
GTGAA

>20477_20477_6_CTSB-TG_CTSB_chr8_11705575_ENST00000530640_TG_chr8_134042125_ENST00000377869_length(amino acids)=580AA_BP=177
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQW
PQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVVQT
HIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKP
ANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLG
GEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYP
AYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTS
ADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_7_CTSB-TG_CTSB_chr8_11705575_ENST00000530640_TG_chr8_134042125_ENST00000519543_length(transcript)=1989nt_BP=669nt
GGCCGGGGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCGCTCCGCTGCGCGCAGGCTGGGCTGC
AGGCTCTCGGCTGCAGCGCTGGGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCTGCTGGTGTTGG
CCAATGCCCGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTGGCAGGCCGGGC
ACAACTTCTACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAGAGTTATGTTTA
CCGAGGACCTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGACCAGGGCTCCT
GTGGCTCCTGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGTGGAGGTGTCGG
CGGAGGACCTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTTCTGGACAAGAA
AAGGCCTGGTTTCTGGTGGCCTCTATGAATCCCATGTAGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGG
CAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGA
TGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCC
CCATGTCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGA
GTGGCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAG
AGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGA
CCAGTAGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGT
ATTACTCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTA
TAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGG
AGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGC
TGAAAATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAA
CCCCCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAG
CCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGG
AGGAGTTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTG
AGCTCCCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATGCG
GTGAAGCAT

>20477_20477_7_CTSB-TG_CTSB_chr8_11705575_ENST00000530640_TG_chr8_134042125_ENST00000519543_length(amino acids)=580AA_BP=177
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQW
PQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVVQT
HIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKP
ANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLG
GEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYP
AYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTS
ADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_8_CTSB-TG_CTSB_chr8_11705575_ENST00000530640_TG_chr8_134042125_ENST00000542445_length(transcript)=1913nt_BP=669nt
GGCCGGGGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCGCTCCGCTGCGCGCAGGCTGGGCTGC
AGGCTCTCGGCTGCAGCGCTGGGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCTGCTGGTGTTGG
CCAATGCCCGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTGGCAGGCCGGGC
ACAACTTCTACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAGAGTTATGTTTA
CCGAGGACCTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGACCAGGGCTCCT
GTGGCTCCTGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGTGGAGGTGTCGG
CGGAGGACCTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTTCTGGACAAGAA
AAGGCCTGGTTTCTGGTGGCCTCTATGAATCCCATGTAGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGG
CAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGA
TGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCC
CCATGTCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGA
GTGGCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAG
AGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGA
CCAGTAGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGT
ATTACTCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTA
TAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGG
AGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGC
TGAAAATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAA
CCCCCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAG
CCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGG
AGGAGTTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTG
AGCTCCCCAAAAACCTCACCCGA

>20477_20477_8_CTSB-TG_CTSB_chr8_11705575_ENST00000530640_TG_chr8_134042125_ENST00000542445_length(amino acids)=580AA_BP=177
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQW
PQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVVQT
HIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKP
ANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLG
GEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYP
AYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTS
ADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_9_CTSB-TG_CTSB_chr8_11705575_ENST00000533455_TG_chr8_134042125_ENST00000220616_length(transcript)=2065nt_BP=751nt
GGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCGCTCCGCTGCGCGCAGGCTGGGCTGCAGGCTC
TCGGCTGCAGCGCTGGGCTGGTGTGCAGTGGTGCGACCACGGCTCACGGCAGCCTCAGCCACCCAGATGTAAGCGATCTGGTTCCCACCT
CAGCCTCCCGAGTAGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCTGCTGGTGTTGGCCAATGCC
CGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTGGCAGGCCGGGCACAACTTC
TACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAGAGTTATGTTTACCGAGGAC
CTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGACCAGGGCTCCTGTGGCTCC
TGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGTGGAGGTGTCGGCGGAGGAC
CTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTTCTGGACAAGAAAAGGCCTG
GTTTCTGGTGGCCTCTATGAATCCCATGTAGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGGCAGCAGAC
CGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGATGGGAGGC
TCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATGTCA
TCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTGGCCCT
TTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAGAGGTCGAT
CTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGTAGC
AAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTACTCT
CTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTATAATCGAC
ATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGGAGCTGCTG
GCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAAATC
ATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCCCCTGG
CCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAGCCGACTGC
TCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAGTTG
ACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTGAGCTCCCC
AAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATGCGGTG

>20477_20477_9_CTSB-TG_CTSB_chr8_11705575_ENST00000533455_TG_chr8_134042125_ENST00000220616_length(amino acids)=580AA_BP=177
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQW
PQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVVQT
HIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKP
ANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLG
GEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYP
AYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTS
ADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_10_CTSB-TG_CTSB_chr8_11705575_ENST00000533455_TG_chr8_134042125_ENST00000377869_length(transcript)=2067nt_BP=751nt
GGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCGCTCCGCTGCGCGCAGGCTGGGCTGCAGGCTC
TCGGCTGCAGCGCTGGGCTGGTGTGCAGTGGTGCGACCACGGCTCACGGCAGCCTCAGCCACCCAGATGTAAGCGATCTGGTTCCCACCT
CAGCCTCCCGAGTAGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCTGCTGGTGTTGGCCAATGCC
CGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTGGCAGGCCGGGCACAACTTC
TACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAGAGTTATGTTTACCGAGGAC
CTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGACCAGGGCTCCTGTGGCTCC
TGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGTGGAGGTGTCGGCGGAGGAC
CTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTTCTGGACAAGAAAAGGCCTG
GTTTCTGGTGGCCTCTATGAATCCCATGTAGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGGCAGCAGAC
CGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGATGGGAGGC
TCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATGTCA
TCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTGGCCCT
TTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAGAGGTCGAT
CTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGTAGC
AAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTACTCT
CTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTATAATCGAC
ATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGGAGCTGCTG
GCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAAATC
ATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCCCCTGG
CCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAGCCGACTGC
TCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAGTTG
ACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTGAGCTCCCC
AAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATGCGGTGAA

>20477_20477_10_CTSB-TG_CTSB_chr8_11705575_ENST00000533455_TG_chr8_134042125_ENST00000377869_length(amino acids)=580AA_BP=177
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQW
PQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVVQT
HIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKP
ANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLG
GEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYP
AYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTS
ADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_11_CTSB-TG_CTSB_chr8_11705575_ENST00000533455_TG_chr8_134042125_ENST00000519543_length(transcript)=2071nt_BP=751nt
GGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCGCTCCGCTGCGCGCAGGCTGGGCTGCAGGCTC
TCGGCTGCAGCGCTGGGCTGGTGTGCAGTGGTGCGACCACGGCTCACGGCAGCCTCAGCCACCCAGATGTAAGCGATCTGGTTCCCACCT
CAGCCTCCCGAGTAGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCTGCTGGTGTTGGCCAATGCC
CGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTGGCAGGCCGGGCACAACTTC
TACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAGAGTTATGTTTACCGAGGAC
CTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGACCAGGGCTCCTGTGGCTCC
TGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGTGGAGGTGTCGGCGGAGGAC
CTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTTCTGGACAAGAAAAGGCCTG
GTTTCTGGTGGCCTCTATGAATCCCATGTAGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGGCAGCAGAC
CGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGATGGGAGGC
TCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATGTCA
TCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTGGCCCT
TTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAGAGGTCGAT
CTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGTAGC
AAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTACTCT
CTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTATAATCGAC
ATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGGAGCTGCTG
GCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAAATC
ATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCCCCTGG
CCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAGCCGACTGC
TCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAGTTG
ACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTGAGCTCCCC
AAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATGCGGTGAAGCA
T

>20477_20477_11_CTSB-TG_CTSB_chr8_11705575_ENST00000533455_TG_chr8_134042125_ENST00000519543_length(amino acids)=580AA_BP=177
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQW
PQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVVQT
HIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKP
ANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLG
GEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYP
AYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTS
ADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_12_CTSB-TG_CTSB_chr8_11705575_ENST00000533455_TG_chr8_134042125_ENST00000542445_length(transcript)=1995nt_BP=751nt
GGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCGCTCCGCTGCGCGCAGGCTGGGCTGCAGGCTC
TCGGCTGCAGCGCTGGGCTGGTGTGCAGTGGTGCGACCACGGCTCACGGCAGCCTCAGCCACCCAGATGTAAGCGATCTGGTTCCCACCT
CAGCCTCCCGAGTAGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCTGCTGGTGTTGGCCAATGCC
CGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTGGCAGGCCGGGCACAACTTC
TACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAGAGTTATGTTTACCGAGGAC
CTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGACCAGGGCTCCTGTGGCTCC
TGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGTGGAGGTGTCGGCGGAGGAC
CTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTTCTGGACAAGAAAAGGCCTG
GTTTCTGGTGGCCTCTATGAATCCCATGTAGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGGCAGCAGAC
CGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGATGGGAGGC
TCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATGTCA
TCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTGGCCCT
TTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAGAGGTCGAT
CTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGTAGC
AAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTACTCT
CTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTATAATCGAC
ATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGGAGCTGCTG
GCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAAATC
ATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCCCCTGG
CCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAGCCGACTGC
TCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAGTTG
ACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTGAGCTCCCC
AAAAACCTCACCCGA

>20477_20477_12_CTSB-TG_CTSB_chr8_11705575_ENST00000533455_TG_chr8_134042125_ENST00000542445_length(amino acids)=580AA_BP=177
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQW
PQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVVQT
HIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKP
ANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLG
GEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYP
AYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTS
ADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_13_CTSB-TG_CTSB_chr8_11705577_ENST00000434271_TG_chr8_134042123_ENST00000220616_length(transcript)=2086nt_BP=770nt
GGGGCGGGGCCGGGAGGGTACTTAGGGCCGGGGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCG
CTCCGCTGCGCGCAGGCTGGGCTGCAGGCTCTCGGCTGCAGCGCTGGGTGAGTGCTGGGGACCCGGGGCCACCGCAGCGTAAGTGACCCA
GAGAGGTGTCCTGATGCCCTCTGTCCTCTCCAGGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCT
GCTGGTGTTGGCCAATGCCCGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTG
GCAGGCCGGGCACAACTTCTACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAG
AGTTATGTTTACCGAGGACCTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGA
CCAGGGCTCCTGTGGCTCCTGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGT
GGAGGTGTCGGCGGAGGACCTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTT
CTGGACAAGAAAAGGCCTGGTTTCTGGTGGCCTCTATGAATCCCATGTAGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGG
CGCGTGTCCCTGGCAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGG
AGAGCTGTGCTGATGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAG
GAGGTCAGTTGCCCCATGTCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAG
CTCCTGGCCGTGAGTGGCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGG
TCTTTATGGGTAGAGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAA
AGTCGAGGCCGGACCAGTAGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCT
GCTGCTACATGGTATTACTCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTT
ATCATCTGCCCTATAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGC
CATGGCAGCCTGGAGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAG
AAGAGCCTGTCGCTGAAAATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTA
CCCACATTTGCAACCCCCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAG
GGCCTGAAGAAAGCCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCA
GAGAGTGAAGAGGAGGAGTTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAG
TGACCAGCCCTTGAGCTCCCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAA
GTATCTACATGCGGTG

>20477_20477_13_CTSB-TG_CTSB_chr8_11705577_ENST00000434271_TG_chr8_134042123_ENST00000220616_length(amino acids)=387AA_BP=
MAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLA
VSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAAT
WYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAYEGQFSLEEKSL
SLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTSADGAKGGQSAESE
EEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_14_CTSB-TG_CTSB_chr8_11705577_ENST00000434271_TG_chr8_134042123_ENST00000377869_length(transcript)=2088nt_BP=770nt
GGGGCGGGGCCGGGAGGGTACTTAGGGCCGGGGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCG
CTCCGCTGCGCGCAGGCTGGGCTGCAGGCTCTCGGCTGCAGCGCTGGGTGAGTGCTGGGGACCCGGGGCCACCGCAGCGTAAGTGACCCA
GAGAGGTGTCCTGATGCCCTCTGTCCTCTCCAGGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCT
GCTGGTGTTGGCCAATGCCCGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTG
GCAGGCCGGGCACAACTTCTACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAG
AGTTATGTTTACCGAGGACCTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGA
CCAGGGCTCCTGTGGCTCCTGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGT
GGAGGTGTCGGCGGAGGACCTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTT
CTGGACAAGAAAAGGCCTGGTTTCTGGTGGCCTCTATGAATCCCATGTAGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGG
CGCGTGTCCCTGGCAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGG
AGAGCTGTGCTGATGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAG
GAGGTCAGTTGCCCCATGTCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAG
CTCCTGGCCGTGAGTGGCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGG
TCTTTATGGGTAGAGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAA
AGTCGAGGCCGGACCAGTAGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCT
GCTGCTACATGGTATTACTCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTT
ATCATCTGCCCTATAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGC
CATGGCAGCCTGGAGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAG
AAGAGCCTGTCGCTGAAAATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTA
CCCACATTTGCAACCCCCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAG
GGCCTGAAGAAAGCCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCA
GAGAGTGAAGAGGAGGAGTTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAG
TGACCAGCCCTTGAGCTCCCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAA
GTATCTACATGCGGTGAA

>20477_20477_14_CTSB-TG_CTSB_chr8_11705577_ENST00000434271_TG_chr8_134042123_ENST00000377869_length(amino acids)=387AA_BP=
MAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLA
VSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAAT
WYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAYEGQFSLEEKSL
SLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTSADGAKGGQSAESE
EEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_15_CTSB-TG_CTSB_chr8_11705577_ENST00000434271_TG_chr8_134042123_ENST00000519543_length(transcript)=2092nt_BP=770nt
GGGGCGGGGCCGGGAGGGTACTTAGGGCCGGGGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCG
CTCCGCTGCGCGCAGGCTGGGCTGCAGGCTCTCGGCTGCAGCGCTGGGTGAGTGCTGGGGACCCGGGGCCACCGCAGCGTAAGTGACCCA
GAGAGGTGTCCTGATGCCCTCTGTCCTCTCCAGGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCT
GCTGGTGTTGGCCAATGCCCGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTG
GCAGGCCGGGCACAACTTCTACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAG
AGTTATGTTTACCGAGGACCTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGA
CCAGGGCTCCTGTGGCTCCTGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGT
GGAGGTGTCGGCGGAGGACCTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTT
CTGGACAAGAAAAGGCCTGGTTTCTGGTGGCCTCTATGAATCCCATGTAGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGG
CGCGTGTCCCTGGCAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGG
AGAGCTGTGCTGATGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAG
GAGGTCAGTTGCCCCATGTCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAG
CTCCTGGCCGTGAGTGGCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGG
TCTTTATGGGTAGAGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAA
AGTCGAGGCCGGACCAGTAGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCT
GCTGCTACATGGTATTACTCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTT
ATCATCTGCCCTATAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGC
CATGGCAGCCTGGAGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAG
AAGAGCCTGTCGCTGAAAATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTA
CCCACATTTGCAACCCCCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAG
GGCCTGAAGAAAGCCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCA
GAGAGTGAAGAGGAGGAGTTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAG
TGACCAGCCCTTGAGCTCCCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAA
GTATCTACATGCGGTGAAGCAT

>20477_20477_15_CTSB-TG_CTSB_chr8_11705577_ENST00000434271_TG_chr8_134042123_ENST00000519543_length(amino acids)=387AA_BP=
MAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLA
VSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAAT
WYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAYEGQFSLEEKSL
SLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTSADGAKGGQSAESE
EEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_16_CTSB-TG_CTSB_chr8_11705577_ENST00000434271_TG_chr8_134042123_ENST00000542445_length(transcript)=2016nt_BP=770nt
GGGGCGGGGCCGGGAGGGTACTTAGGGCCGGGGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCG
CTCCGCTGCGCGCAGGCTGGGCTGCAGGCTCTCGGCTGCAGCGCTGGGTGAGTGCTGGGGACCCGGGGCCACCGCAGCGTAAGTGACCCA
GAGAGGTGTCCTGATGCCCTCTGTCCTCTCCAGGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCT
GCTGGTGTTGGCCAATGCCCGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTG
GCAGGCCGGGCACAACTTCTACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAG
AGTTATGTTTACCGAGGACCTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGA
CCAGGGCTCCTGTGGCTCCTGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGT
GGAGGTGTCGGCGGAGGACCTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTT
CTGGACAAGAAAAGGCCTGGTTTCTGGTGGCCTCTATGAATCCCATGTAGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGG
CGCGTGTCCCTGGCAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGG
AGAGCTGTGCTGATGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAG
GAGGTCAGTTGCCCCATGTCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAG
CTCCTGGCCGTGAGTGGCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGG
TCTTTATGGGTAGAGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAA
AGTCGAGGCCGGACCAGTAGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCT
GCTGCTACATGGTATTACTCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTT
ATCATCTGCCCTATAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGC
CATGGCAGCCTGGAGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAG
AAGAGCCTGTCGCTGAAAATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTA
CCCACATTTGCAACCCCCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAG
GGCCTGAAGAAAGCCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCA
GAGAGTGAAGAGGAGGAGTTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAG
TGACCAGCCCTTGAGCTCCCCAAAAACCTCACCCGA

>20477_20477_16_CTSB-TG_CTSB_chr8_11705577_ENST00000434271_TG_chr8_134042123_ENST00000542445_length(amino acids)=387AA_BP=
MAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLA
VSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAAT
WYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAYEGQFSLEEKSL
SLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTSADGAKGGQSAESE
EEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_17_CTSB-TG_CTSB_chr8_11705577_ENST00000530640_TG_chr8_134042123_ENST00000220616_length(transcript)=1985nt_BP=669nt
GGCCGGGGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCGCTCCGCTGCGCGCAGGCTGGGCTGC
AGGCTCTCGGCTGCAGCGCTGGGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCTGCTGGTGTTGG
CCAATGCCCGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTGGCAGGCCGGGC
ACAACTTCTACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAGAGTTATGTTTA
CCGAGGACCTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGACCAGGGCTCCT
GTGGCTCCTGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGTGGAGGTGTCGG
CGGAGGACCTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTTCTGGACAAGAA
AAGGCCTGGTTTCTGGTGGCCTCTATGAATCCCATGTAGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCT
GGCAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCT
GATGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTG
CCCCATGTCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGT
GAGTGGCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGT
AGAGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCG
GACCAGTAGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATG
GTATTACTCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCC
TATAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCT
GGAGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTC
GCTGAAAATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGC
AACCCCCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAA
AGCCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGA
GGAGGAGTTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCT
TGAGCTCCCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATG
CGGTG

>20477_20477_17_CTSB-TG_CTSB_chr8_11705577_ENST00000530640_TG_chr8_134042123_ENST00000220616_length(amino acids)=387AA_BP=
MAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLA
VSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAAT
WYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAYEGQFSLEEKSL
SLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTSADGAKGGQSAESE
EEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_18_CTSB-TG_CTSB_chr8_11705577_ENST00000530640_TG_chr8_134042123_ENST00000377869_length(transcript)=1987nt_BP=669nt
GGCCGGGGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCGCTCCGCTGCGCGCAGGCTGGGCTGC
AGGCTCTCGGCTGCAGCGCTGGGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCTGCTGGTGTTGG
CCAATGCCCGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTGGCAGGCCGGGC
ACAACTTCTACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAGAGTTATGTTTA
CCGAGGACCTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGACCAGGGCTCCT
GTGGCTCCTGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGTGGAGGTGTCGG
CGGAGGACCTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTTCTGGACAAGAA
AAGGCCTGGTTTCTGGTGGCCTCTATGAATCCCATGTAGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCT
GGCAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCT
GATGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTG
CCCCATGTCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGT
GAGTGGCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGT
AGAGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCG
GACCAGTAGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATG
GTATTACTCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCC
TATAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCT
GGAGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTC
GCTGAAAATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGC
AACCCCCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAA
AGCCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGA
GGAGGAGTTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCT
TGAGCTCCCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATG
CGGTGAA

>20477_20477_18_CTSB-TG_CTSB_chr8_11705577_ENST00000530640_TG_chr8_134042123_ENST00000377869_length(amino acids)=387AA_BP=
MAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLA
VSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAAT
WYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAYEGQFSLEEKSL
SLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTSADGAKGGQSAESE
EEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_19_CTSB-TG_CTSB_chr8_11705577_ENST00000530640_TG_chr8_134042123_ENST00000519543_length(transcript)=1991nt_BP=669nt
GGCCGGGGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCGCTCCGCTGCGCGCAGGCTGGGCTGC
AGGCTCTCGGCTGCAGCGCTGGGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCTGCTGGTGTTGG
CCAATGCCCGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTGGCAGGCCGGGC
ACAACTTCTACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAGAGTTATGTTTA
CCGAGGACCTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGACCAGGGCTCCT
GTGGCTCCTGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGTGGAGGTGTCGG
CGGAGGACCTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTTCTGGACAAGAA
AAGGCCTGGTTTCTGGTGGCCTCTATGAATCCCATGTAGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCT
GGCAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCT
GATGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTG
CCCCATGTCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGT
GAGTGGCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGT
AGAGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCG
GACCAGTAGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATG
GTATTACTCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCC
TATAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCT
GGAGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTC
GCTGAAAATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGC
AACCCCCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAA
AGCCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGA
GGAGGAGTTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCT
TGAGCTCCCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATG
CGGTGAAGCAT

>20477_20477_19_CTSB-TG_CTSB_chr8_11705577_ENST00000530640_TG_chr8_134042123_ENST00000519543_length(amino acids)=387AA_BP=
MAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLA
VSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAAT
WYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAYEGQFSLEEKSL
SLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTSADGAKGGQSAESE
EEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_20_CTSB-TG_CTSB_chr8_11705577_ENST00000530640_TG_chr8_134042123_ENST00000542445_length(transcript)=1915nt_BP=669nt
GGCCGGGGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCGCTCCGCTGCGCGCAGGCTGGGCTGC
AGGCTCTCGGCTGCAGCGCTGGGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCTGCTGGTGTTGG
CCAATGCCCGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTGGCAGGCCGGGC
ACAACTTCTACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAGAGTTATGTTTA
CCGAGGACCTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGACCAGGGCTCCT
GTGGCTCCTGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGTGGAGGTGTCGG
CGGAGGACCTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTTCTGGACAAGAA
AAGGCCTGGTTTCTGGTGGCCTCTATGAATCCCATGTAGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCT
GGCAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCT
GATGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTG
CCCCATGTCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGT
GAGTGGCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGT
AGAGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCG
GACCAGTAGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATG
GTATTACTCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCC
TATAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCT
GGAGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTC
GCTGAAAATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGC
AACCCCCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAA
AGCCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGA
GGAGGAGTTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCT
TGAGCTCCCCAAAAACCTCACCCGA

>20477_20477_20_CTSB-TG_CTSB_chr8_11705577_ENST00000530640_TG_chr8_134042123_ENST00000542445_length(amino acids)=387AA_BP=
MAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLA
VSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAAT
WYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAYEGQFSLEEKSL
SLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTSADGAKGGQSAESE
EEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_21_CTSB-TG_CTSB_chr8_11705577_ENST00000533455_TG_chr8_134042123_ENST00000220616_length(transcript)=2067nt_BP=751nt
GGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCGCTCCGCTGCGCGCAGGCTGGGCTGCAGGCTC
TCGGCTGCAGCGCTGGGCTGGTGTGCAGTGGTGCGACCACGGCTCACGGCAGCCTCAGCCACCCAGATGTAAGCGATCTGGTTCCCACCT
CAGCCTCCCGAGTAGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCTGCTGGTGTTGGCCAATGCC
CGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTGGCAGGCCGGGCACAACTTC
TACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAGAGTTATGTTTACCGAGGAC
CTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGACCAGGGCTCCTGTGGCTCC
TGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGTGGAGGTGTCGGCGGAGGAC
CTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTTCTGGACAAGAAAAGGCCTG
GTTTCTGGTGGCCTCTATGAATCCCATGTAGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGGCAGCAG
ACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGATGGGAG
GCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATGT
CATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTGGCC
CTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAGAGGTCG
ATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGTA
GCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTACT
CTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTATAATCG
ACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGGAGCTGC
TGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAAA
TCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCCCCT
GGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAGCCGACT
GCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAGT
TGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTGAGCTCC
CCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATGCGGTG

>20477_20477_21_CTSB-TG_CTSB_chr8_11705577_ENST00000533455_TG_chr8_134042123_ENST00000220616_length(amino acids)=387AA_BP=
MAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLA
VSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAAT
WYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAYEGQFSLEEKSL
SLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTSADGAKGGQSAESE
EEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_22_CTSB-TG_CTSB_chr8_11705577_ENST00000533455_TG_chr8_134042123_ENST00000377869_length(transcript)=2069nt_BP=751nt
GGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCGCTCCGCTGCGCGCAGGCTGGGCTGCAGGCTC
TCGGCTGCAGCGCTGGGCTGGTGTGCAGTGGTGCGACCACGGCTCACGGCAGCCTCAGCCACCCAGATGTAAGCGATCTGGTTCCCACCT
CAGCCTCCCGAGTAGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCTGCTGGTGTTGGCCAATGCC
CGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTGGCAGGCCGGGCACAACTTC
TACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAGAGTTATGTTTACCGAGGAC
CTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGACCAGGGCTCCTGTGGCTCC
TGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGTGGAGGTGTCGGCGGAGGAC
CTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTTCTGGACAAGAAAAGGCCTG
GTTTCTGGTGGCCTCTATGAATCCCATGTAGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGGCAGCAG
ACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGATGGGAG
GCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATGT
CATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTGGCC
CTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAGAGGTCG
ATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGTA
GCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTACT
CTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTATAATCG
ACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGGAGCTGC
TGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAAA
TCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCCCCT
GGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAGCCGACT
GCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAGT
TGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTGAGCTCC
CCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATGCGGTGAA

>20477_20477_22_CTSB-TG_CTSB_chr8_11705577_ENST00000533455_TG_chr8_134042123_ENST00000377869_length(amino acids)=387AA_BP=
MAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLA
VSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAAT
WYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAYEGQFSLEEKSL
SLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTSADGAKGGQSAESE
EEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_23_CTSB-TG_CTSB_chr8_11705577_ENST00000533455_TG_chr8_134042123_ENST00000519543_length(transcript)=2073nt_BP=751nt
GGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCGCTCCGCTGCGCGCAGGCTGGGCTGCAGGCTC
TCGGCTGCAGCGCTGGGCTGGTGTGCAGTGGTGCGACCACGGCTCACGGCAGCCTCAGCCACCCAGATGTAAGCGATCTGGTTCCCACCT
CAGCCTCCCGAGTAGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCTGCTGGTGTTGGCCAATGCC
CGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTGGCAGGCCGGGCACAACTTC
TACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAGAGTTATGTTTACCGAGGAC
CTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGACCAGGGCTCCTGTGGCTCC
TGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGTGGAGGTGTCGGCGGAGGAC
CTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTTCTGGACAAGAAAAGGCCTG
GTTTCTGGTGGCCTCTATGAATCCCATGTAGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGGCAGCAG
ACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGATGGGAG
GCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATGT
CATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTGGCC
CTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAGAGGTCG
ATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGTA
GCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTACT
CTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTATAATCG
ACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGGAGCTGC
TGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAAA
TCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCCCCT
GGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAGCCGACT
GCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAGT
TGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTGAGCTCC
CCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATGCGGTGAAG
CAT

>20477_20477_23_CTSB-TG_CTSB_chr8_11705577_ENST00000533455_TG_chr8_134042123_ENST00000519543_length(amino acids)=387AA_BP=
MAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLA
VSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAAT
WYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAYEGQFSLEEKSL
SLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTSADGAKGGQSAESE
EEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>20477_20477_24_CTSB-TG_CTSB_chr8_11705577_ENST00000533455_TG_chr8_134042123_ENST00000542445_length(transcript)=1997nt_BP=751nt
GGCTGGCCCAGGCTACGGCGGCTGCAGGGCTCCGGCAACCGCTCCGGCAACGCCAACCGCTCCGCTGCGCGCAGGCTGGGCTGCAGGCTC
TCGGCTGCAGCGCTGGGCTGGTGTGCAGTGGTGCGACCACGGCTCACGGCAGCCTCAGCCACCCAGATGTAAGCGATCTGGTTCCCACCT
CAGCCTCCCGAGTAGTGGATCTAGGATCCGGCTTCCAACATGTGGCAGCTCTGGGCCTCCCTCTGCTGCCTGCTGGTGTTGGCCAATGCC
CGGAGCAGGCCCTCTTTCCATCCCCTGTCGGATGAGCTGGTCAACTATGTCAACAAACGGAATACCACGTGGCAGGCCGGGCACAACTTC
TACAACGTGGACATGAGCTACTTGAAGAGGCTATGTGGTACCTTCCTGGGTGGGCCCAAGCCACCCCAGAGAGTTATGTTTACCGAGGAC
CTGAAGCTGCCTGCAAGCTTCGATGCACGGGAACAATGGCCACAGTGTCCCACCATCAAAGAGATCAGAGACCAGGGCTCCTGTGGCTCC
TGCTGGGCCTTCGGGGCTGTGGAAGCCATCTCTGACCGGATCTGCATCCACACCAATGCGCACGTCAGCGTGGAGGTGTCGGCGGAGGAC
CTGCTCACATGCTGTGGCAGCATGTGTGGGGACGGCTGTAATGGTGGCTATCCTGCTGAAGCTTGGAACTTCTGGACAAGAAAAGGCCTG
GTTTCTGGTGGCCTCTATGAATCCCATGTAGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGGCAGCAG
ACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGATGGGAG
GCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATGT
CATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTGGCC
CTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAGAGGTCG
ATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGTA
GCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTACT
CTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTATAATCG
ACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGGAGCTGC
TGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAAA
TCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCCCCT
GGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAGCCGACT
GCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAGT
TGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTGAGCTCC
CCAAAAACCTCACCCGA

>20477_20477_24_CTSB-TG_CTSB_chr8_11705577_ENST00000533455_TG_chr8_134042123_ENST00000542445_length(amino acids)=387AA_BP=
MAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLA
VSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAAT
WYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAYEGQFSLEEKSL
SLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTSADGAKGGQSAESE
EEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CTSB-TG


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CTSB-TG


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CTSB-TG


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCTSBC0027626Neoplasm Invasiveness2CTD_human
HgeneCTSBC0007134Renal Cell Carcinoma1CTD_human
HgeneCTSBC0017636Glioblastoma1CTD_human
HgeneCTSBC0026848Myopathy1CTD_human
HgeneCTSBC0027540Necrosis1CTD_human
HgeneCTSBC0033578Prostatic Neoplasms1CTD_human
HgeneCTSBC0033687Proteinuria1CTD_human
HgeneCTSBC0235874Disease Exacerbation1CTD_human
HgeneCTSBC0279702Conventional (Clear Cell) Renal Cell Carcinoma1CTD_human
HgeneCTSBC0334588Giant Cell Glioblastoma1CTD_human
HgeneCTSBC0376358Malignant neoplasm of prostate1CTD_human
HgeneCTSBC0406756Keratolytic winter erythema1CTD_human;ORPHANET
HgeneCTSBC1266042Chromophobe Renal Cell Carcinoma1CTD_human
HgeneCTSBC1266043Sarcomatoid Renal Cell Carcinoma1CTD_human
HgeneCTSBC1266044Collecting Duct Carcinoma of the Kidney1CTD_human
HgeneCTSBC1306837Papillary Renal Cell Carcinoma1CTD_human
HgeneCTSBC1621958Glioblastoma Multiforme1CTD_human
TgeneC0342194Thyroid Dyshormonogenesis 38CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneC0018021Goiter2CTD_human
TgeneC1848805Thyroid Dyshormonogenesis 12ORPHANET
TgeneC0003469Anxiety Disorders1CTD_human
TgeneC0004364Autoimmune Diseases1CTD_human
TgeneC0010308Congenital Hypothyroidism1GENOMICS_ENGLAND
TgeneC0011573Endogenous depression1CTD_human
TgeneC0011581Depressive disorder1CTD_human
TgeneC0013336Dwarfism1CTD_human
TgeneC0025193Melancholia1CTD_human
TgeneC0041696Unipolar Depression1CTD_human
TgeneC0086133Depressive Syndrome1CTD_human
TgeneC0282126Depression, Neurotic1CTD_human
TgeneC0376280Anxiety States, Neurotic1CTD_human
TgeneC0677607Hashimoto Disease1CTD_human
TgeneC0920350Autoimmune thyroiditis1CTD_human
TgeneC1279420Anxiety neurosis (finding)1CTD_human