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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
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Fusion gene:XXYLT1-ACAP2 (FusionGDB2 ID:HG152002TG23527)

Fusion Gene Summary for XXYLT1-ACAP2

Fusion gene summary

Fusion gene information	Fusion gene name: XXYLT1-ACAP2
	Fusion gene ID: hg152002tg23527
		Hgene	Tgene
	Gene symbol	XXYLT1	ACAP2
	Gene ID	152002	23527
	Gene name	xyloside xylosyltransferase 1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
	Synonyms	C3orf21	CENTB2\|CNT-B2
	Cytomap	('XXYLT1')('ACAP2') 3q29	3q29
	Type of gene	protein-coding	protein-coding
	Description	xyloside xylosyltransferase 1UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase	arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2Arf GAP with coiled coil, ANK repeat and PH domains 2centaurin-beta-2
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000310380, ENST00000355729, ENST00000429994, ENST00000437101, ENST00000356740, ENST00000460582,	ENST00000356740, ENST00000460582, ENST00000355729, ENST00000429994, ENST00000437101, ENST00000310380,
Fusion gene scores	* DoF score	10 X 6 X 7=420	9 X 9 X 3=243
	# samples	11	10
	** MAII score	log2(11/420*10)=-1.93288580414146 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(10/243*10)=-1.28095631383106 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: XXYLT1 [Title/Abstract] AND ACAP2 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	XXYLT1(194877178)-ACAP2(195112876), # samples:2 XXYLT1(194991284)-ACAP2(195066046), # samples:2
Anticipated loss of major functional domain due to fusion event.	XXYLT1-ACAP2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. XXYLT1-ACAP2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. XXYLT1-ACAP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. XXYLT1-ACAP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ACAP2-XXYLT1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ACAP2-XXYLT1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. XXYLT1-ACAP2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. ACAP2-XXYLT1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	XXYLT1	GO:0016266	O-glycan processing	8982869\|22117070
Tgene	ACAP2	GO:0030029	actin filament-based process	11062263

Fusion gene breakpoints across XXYLT1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across ACAP2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-A2-A0D2-01A	XXYLT1	chr3	194877178	-	ACAP2	chr3	195112876	-
ChimerDB4	BRCA	TCGA-B6-A0RS-01A	XXYLT1	chr3	194991284	-	ACAP2	chr3	195066046	-

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Fusion Gene ORF analysis for XXYLT1-ACAP2

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000310380	ENST00000472860	XXYLT1	chr3	194877178	-	ACAP2	chr3	195112876	-
5CDS-intron	ENST00000310380	ENST00000472860	XXYLT1	chr3	194991284	-	ACAP2	chr3	195066046	-
5CDS-intron	ENST00000355729	ENST00000472860	XXYLT1	chr3	194877178	-	ACAP2	chr3	195112876	-
5CDS-intron	ENST00000429994	ENST00000472860	XXYLT1	chr3	194877178	-	ACAP2	chr3	195112876	-
5CDS-intron	ENST00000437101	ENST00000472860	XXYLT1	chr3	194877178	-	ACAP2	chr3	195112876	-
Frame-shift	ENST00000437101	ENST00000326793	XXYLT1	chr3	194877178	-	ACAP2	chr3	195112876	-
In-frame	ENST00000310380	ENST00000326793	XXYLT1	chr3	194877178	-	ACAP2	chr3	195112876	-
In-frame	ENST00000310380	ENST00000326793	XXYLT1	chr3	194991284	-	ACAP2	chr3	195066046	-
In-frame	ENST00000355729	ENST00000326793	XXYLT1	chr3	194877178	-	ACAP2	chr3	195112876	-
In-frame	ENST00000429994	ENST00000326793	XXYLT1	chr3	194877178	-	ACAP2	chr3	195112876	-
intron-3CDS	ENST00000355729	ENST00000326793	XXYLT1	chr3	194991284	-	ACAP2	chr3	195066046	-
intron-3CDS	ENST00000356740	ENST00000326793	XXYLT1	chr3	194877178	-	ACAP2	chr3	195112876	-
intron-3CDS	ENST00000356740	ENST00000326793	XXYLT1	chr3	194991284	-	ACAP2	chr3	195066046	-
intron-3CDS	ENST00000429994	ENST00000326793	XXYLT1	chr3	194991284	-	ACAP2	chr3	195066046	-
intron-3CDS	ENST00000437101	ENST00000326793	XXYLT1	chr3	194991284	-	ACAP2	chr3	195066046	-
intron-3CDS	ENST00000460582	ENST00000326793	XXYLT1	chr3	194877178	-	ACAP2	chr3	195112876	-
intron-3CDS	ENST00000460582	ENST00000326793	XXYLT1	chr3	194991284	-	ACAP2	chr3	195066046	-
intron-intron	ENST00000355729	ENST00000472860	XXYLT1	chr3	194991284	-	ACAP2	chr3	195066046	-
intron-intron	ENST00000356740	ENST00000472860	XXYLT1	chr3	194877178	-	ACAP2	chr3	195112876	-
intron-intron	ENST00000356740	ENST00000472860	XXYLT1	chr3	194991284	-	ACAP2	chr3	195066046	-
intron-intron	ENST00000429994	ENST00000472860	XXYLT1	chr3	194991284	-	ACAP2	chr3	195066046	-
intron-intron	ENST00000437101	ENST00000472860	XXYLT1	chr3	194991284	-	ACAP2	chr3	195066046	-
intron-intron	ENST00000460582	ENST00000472860	XXYLT1	chr3	194877178	-	ACAP2	chr3	195112876	-
intron-intron	ENST00000460582	ENST00000472860	XXYLT1	chr3	194991284	-	ACAP2	chr3	195066046	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000310380	XXYLT1	chr3	194877178	-	ENST00000326793	ACAP2	chr3	195112876	-	7770	894	109	3177	1022
ENST00000429994	XXYLT1	chr3	194877178	-	ENST00000326793	ACAP2	chr3	195112876	-	7306	430	68	2713	881
ENST00000355729	XXYLT1	chr3	194877178	-	ENST00000326793	ACAP2	chr3	195112876	-	7052	176	0	2459	819

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000310380	ENST00000326793	XXYLT1	chr3	194877178	-	ACAP2	chr3	195112876	-	9.05E-05	0.9999095
ENST00000429994	ENST00000326793	XXYLT1	chr3	194877178	-	ACAP2	chr3	195112876	-	8.59E-05	0.99991405
ENST00000355729	ENST00000326793	XXYLT1	chr3	194877178	-	ACAP2	chr3	195112876	-	0.000729111	0.99927086

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Fusion Genomic Features for XXYLT1-ACAP2

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

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Fusion Protein Features for XXYLT1-ACAP2

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:194877178/chr3:195112876)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

XXYLT1

chr3:194877178

chr3:195112876

ENST00000310380

104_106

261

394.0

Region

UDP-alpha-D-xylose binding

Hgene

XXYLT1

chr3:194991284

chr3:195066046

ENST00000310380

104_106

168

394.0

Region

UDP-alpha-D-xylose binding

Hgene

XXYLT1

chr3:194877178

chr3:195112876

ENST00000310380

1_23

261

394.0

Topological domain

Cytoplasmic

Hgene

XXYLT1

chr3:194877178

chr3:195112876

ENST00000355729

1_23

191.0

Topological domain

Cytoplasmic

Hgene

XXYLT1

chr3:194877178

chr3:195112876

ENST00000437101

1_23

191.0

Topological domain

Cytoplasmic

Hgene

XXYLT1

chr3:194991284

chr3:195066046

ENST00000310380

1_23

168

394.0

Topological domain

Cytoplasmic

Hgene

XXYLT1

chr3:194877178

chr3:195112876

ENST00000310380

24_44

261

394.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Hgene

XXYLT1

chr3:194877178

chr3:195112876

ENST00000355729

24_44

191.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Hgene

XXYLT1

chr3:194877178

chr3:195112876

ENST00000437101

24_44

191.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Hgene

XXYLT1

chr3:194991284

chr3:195066046

ENST00000310380

24_44

168

394.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Tgene

ACAP2

chr3:194877178

chr3:195112876

ENST00000326793

266_361

779.0

Domain

Tgene

ACAP2

chr3:194877178

chr3:195112876

ENST00000326793

399_520

779.0

Domain

Arf-GAP

Tgene

ACAP2

chr3:194991284

chr3:195066046

ENST00000326793

266_361

779.0

Domain

Tgene

ACAP2

chr3:194991284

chr3:195066046

ENST00000326793

399_520

779.0

Domain

Arf-GAP

Tgene

ACAP2

chr3:194877178

chr3:195112876

ENST00000326793

640_669

779.0

Repeat

Note=ANK 1

Tgene

ACAP2

chr3:194877178

chr3:195112876

ENST00000326793

673_702

779.0

Repeat

Note=ANK 2

Tgene

ACAP2

chr3:194877178

chr3:195112876

ENST00000326793

706_735

779.0

Repeat

Note=ANK 3

Tgene

ACAP2

chr3:194991284

chr3:195066046

ENST00000326793

640_669

779.0

Repeat

Note=ANK 1

Tgene

ACAP2

chr3:194991284

chr3:195066046

ENST00000326793

673_702

779.0

Repeat

Note=ANK 2

Tgene

ACAP2

chr3:194991284

chr3:195066046

ENST00000326793

706_735

779.0

Repeat

Note=ANK 3

Tgene

ACAP2

chr3:194877178

chr3:195112876

ENST00000326793

414_437

779.0

Zinc finger

C4-type

Tgene

ACAP2

chr3:194991284

chr3:195066046

ENST00000326793

414_437

779.0

Zinc finger

C4-type

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

XXYLT1

chr3:194877178

chr3:195112876

ENST00000355729

104_106

191.0

Region

UDP-alpha-D-xylose binding

Hgene

XXYLT1

chr3:194877178

chr3:195112876

ENST00000356740

104_106

188.0

Region

UDP-alpha-D-xylose binding

Hgene

XXYLT1

chr3:194877178

chr3:195112876

ENST00000437101

104_106

191.0

Region

UDP-alpha-D-xylose binding

Hgene

XXYLT1

chr3:194991284

chr3:195066046

ENST00000355729

104_106

191.0

Region

UDP-alpha-D-xylose binding

Hgene

XXYLT1

chr3:194991284

chr3:195066046

ENST00000356740

104_106

188.0

Region

UDP-alpha-D-xylose binding

Hgene

XXYLT1

chr3:194991284

chr3:195066046

ENST00000437101

104_106

191.0

Region

UDP-alpha-D-xylose binding

Hgene

XXYLT1

chr3:194877178

chr3:195112876

ENST00000310380

45_393

261

394.0

Topological domain

Lumenal

Hgene

XXYLT1

chr3:194877178

chr3:195112876

ENST00000355729

45_393

191.0

Topological domain

Lumenal

Hgene

XXYLT1

chr3:194877178

chr3:195112876

ENST00000356740

1_23

188.0

Topological domain

Cytoplasmic

Hgene

XXYLT1

chr3:194877178

chr3:195112876

ENST00000356740

45_393

188.0

Topological domain

Lumenal

Hgene

XXYLT1

chr3:194877178

chr3:195112876

ENST00000437101

45_393

191.0

Topological domain

Lumenal

Hgene

XXYLT1

chr3:194991284

chr3:195066046

ENST00000310380

45_393

168

394.0

Topological domain

Lumenal

Hgene

XXYLT1

chr3:194991284

chr3:195066046

ENST00000355729

1_23

191.0

Topological domain

Cytoplasmic

Hgene

XXYLT1

chr3:194991284

chr3:195066046

ENST00000355729

45_393

191.0

Topological domain

Lumenal

Hgene

XXYLT1

chr3:194991284

chr3:195066046

ENST00000356740

1_23

188.0

Topological domain

Cytoplasmic

Hgene

XXYLT1

chr3:194991284

chr3:195066046

ENST00000356740

45_393

188.0

Topological domain

Lumenal

Hgene

XXYLT1

chr3:194991284

chr3:195066046

ENST00000437101

1_23

191.0

Topological domain

Cytoplasmic

Hgene

XXYLT1

chr3:194991284

chr3:195066046

ENST00000437101

45_393

191.0

Topological domain

Lumenal

Hgene

XXYLT1

chr3:194877178

chr3:195112876

ENST00000356740

24_44

188.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Hgene

XXYLT1

chr3:194991284

chr3:195066046

ENST00000355729

24_44

191.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Hgene

XXYLT1

chr3:194991284

chr3:195066046

ENST00000356740

24_44

188.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Hgene

XXYLT1

chr3:194991284

chr3:195066046

ENST00000437101

24_44

191.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Tgene

ACAP2

chr3:194877178

chr3:195112876

ENST00000326793

1_226

779.0

Domain

Note=BAR

Tgene

ACAP2

chr3:194991284

chr3:195066046

ENST00000326793

1_226

779.0

Domain

Note=BAR

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Fusion Gene Sequence for XXYLT1-ACAP2

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>99833_99833_1_XXYLT1-ACAP2_XXYLT1_chr3_194877178_ENST00000310380_ACAP2_chr3_195112876_ENST00000326793_length(transcript)=7770nt_BP=894nt
CCCCTTTCATGGCCGCCGCCTGGCGCCGGGGCTAAGTGGCCGCCGGCGTCCGGGTACCCGAGGGCTCTCCCGCGTTGCTGGCACCGCTGG
CGCCGCGGTCTCGTAGCGCATGGGCCTCCTCCGAGGCGGGCTCCCATGCGCTCGGGCCATGGCGCGCCTGGGCGCTGTGCGCTCCCACTA
CTGCGCCCTGCTGCTGGCCGCGGCGCTGGCCGTCTGCGCCTTCTACTACCTCGGCTCAGGCCGGGAGACCTTCTCCAGCGCCACCAAGAG
GCTGAAGGAGGCCCGCGCCGGGGCTCCCGCCGCGCCCTCGCCGCCCGCGCTGGAGCTAGCGCGGGGCTCCGTGGCGCCAGCCCCCGGCGC
GAAGGCCAAGAGCTTGGAGGGCGGCGGTGCCGGGCCGGTGGACTACCACCTGCTGATGATGTTCACCAAGGCGGAGCACAATGCCGCGCT
GCAGGCCAAGGCCCGCGTCGCGCTGCGCTCACTGCTGCGCCTCGCCAAGTTCGAGGCGCACGAGGTGCTTAACCTTCACTTCGTGAGCGA
GGAGGCCAGCCGCGAGGTGGCCAAGGGCCTGCTGCGGGAGCTCCTGCCGCCCGCCGCTGGCTTCAAGTGCAAGGTCATCTTCCACGATGT
TGCTGTGCTGACGGATAAGCTCTTCCCCATCGTGGAGGCCATGCAGAAGCACTTCAGTGCTGGCTTGGGAACCTACTACAGTGACTCCAT
CTTCTTCCTCTCGGTCGCCATGCATCAGATCATGCCCAAAGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACCAA
CATCCGGGAGTTGTTTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGGCAGC
TTTGGAAGAAGTAGAAGGTGATGTGGCAGAATTGGAACTAAAACTTGATAAGCTTGTGAAACTTTGTATTGCAATGATTGATACTGGAAA
AGCCTTTTGTGTTGCAAATAAACAGTTCATGAATGGGATTCGAGACCTGGCTCAGTATTCTAGTAATGATGCTGTCGTTGAGACAAGTTT
GACCAAGTTTTCTGACAGTCTTCAAGAAATGATAAATTTTCACACAATCCTGTTTGACCAAACTCAGAGATCAATTAAGGCACAGCTTCA
GAACTTTGTTAAAGAAGATCTTAGAAAATTCAAAGATGCCAAGAAGCAATTCGAAAAAGTCAGTGAAGAAAAAGAAAATGCGTTAGTAAA
AAATGCCCAAGTACAAAGAAACAAACAACATGAAGTTGAAGAAGCCACCAACATTCTGACAGCAACAAGAAAATGTTTCCGACACATAGC
CCTCGATTATGTGCTTCAGATTAATGTTCTTCAATCAAAAAGGAGATCAGAAATCCTAAAATCAATGTTGTCATTTATGTATGCCCATTT
GGCCTTCTTTCATCAAGGATATGATCTGTTTAGTGAACTTGGACCCTACATGAAGGATCTTGGTGCACAGTTGGATCGACTGGTTGTGGA
TGCAGCAAAGGAGAAAAGAGAAATGGAGCAAAAACATTCCACCATTCAACAAAAGGATTTCTCCAGTGATGATTCTAAGTTAGAATATAA
CGTAGATGCTGCAAATGGCATAGTTATGGAAGGATATCTGTTCAAACGAGCCAGCAATGCCTTCAAAACTTGGAACAGGCGCTGGTTTTC
AATACAGAATAATCAGTTGGTTTACCAGAAAAAATTTAAGGATAATCCGACTGTGGTAGTTGAAGACCTCAGGCTTTGCACAGTGAAACA
TTGTGAAGACATAGAGCGACGATTCTGCTTTGAGGTGGTCTCGCCAACAAAAAGTTGCATGCTCCAGGCAGATTCCGAAAAGCTGCGCCA
GGCATGGATTAAGGCTGTTCAGACCAGTATTGCTACTGCTTATAGAGAGAAGGGTGATGAATCAGAGAAGCTGGATAAGAAATCATCTCC
ATCCACAGGAAGCCTAGATTCTGGAAATGAGTCCAAAGAGAAATTATTGAAAGGAGAAAGTGCGCTTCAGCGGGTCCAGTGTATCCCTGG
CAATGCCAGCTGTTGTGACTGTGGCCTGGCAGATCCACGGTGGGCCAGCATCAACCTGGGCATCACCTTGTGTATCGAGTGCTCCGGAAT
TCACCGGAGCCTTGGGGTTCATTTTTCAAAAGTACGATCTTTAACTTTAGACACCTGGGAGCCAGAACTTTTAAAGCTTATGTGTGAGTT
GGGGAATGATGTTATAAATCGAGTTTATGAAGCTAATGTGGAAAAAATGGGAATAAAGAAACCCCAACCAGGACAAAGACAGGAGAAGGA
GGCATATATCAGAGCAAAATATGTGGAGAGGAAATTTGTGGATAAATATTCTATATCATTATCACCTCCTGAGCAGCAAAAAAAGTTTGT
CTCTAAAAGTTCTGAAGAAAAGAGGCTGAGCATTTCTAAATTTGGGCCAGGGGACCAAGTCAGAGCATCTGCCCAAAGTTCAGTCAGAAG
TAATGACAGTGGAATTCAGCAGAGCTCTGATGATGGAAGAGAATCTTTACCCTCCACGGTGTCAGCCAATAGTTTATATGAGCCTGAAGG
AGAAAGGCAAGATTCTTCTATGTTTCTTGACTCGAAACATCTTAATCCAGGACTTCAGCTTTATAGGGCGTCATATGAAAAAAACCTTCC
TAAAATGGCTGAGGCTTTGGCTCATGGTGCAGACGTGAACTGGGCCAATTCAGAGGAAAACAAAGCGACACCACTTATTCAGGCTGTATT
AGGGGGCTCTTTGGTGACGTGTGAGTTCCTCCTACAGAATGGTGCTAATGTCAACCAAAGAGATGTCCAAGGGCGGGGACCATTGCACCA
TGCCACCGTCTTAGGGCACACAGGGCAGGTATGTTTATTCCTAAAACGAGGTGCCAATCAACATGCCACTGATGAAGAAGGGAAAGACCC
TTTGAGCATAGCTGTGGAAGCAGCCAATGCTGATATAGTCACCTTGTTACGTTTAGCAAGAATGAATGAAGAGATGCGGGAATCAGAAGG
ACTTTATGGACAGCCAGGTGATGAAACTTATCAGGACATATTTCGTGATTTTTCCCAAATGGCATCCAATAATCCAGAGAAACTAAATCG
TTTCCAGCAAGATTCACAGAAATTCTGAATTTTTTTAAAAATGGGAAAATATGAAATCTGGTGACCCCCTAATGTATACAGCTAAAAAAT
CACAATTTTTTTACTGCTTTAATTCTACTTAATTTTGGTAGATATTGAATGGCTTGGAAAAGAGGTACCCATTCATATATTTATAAATTA
AAACATAGTTATCTAGTAGTAGGAGAGGAACCTAGTTTAGGACCTCTTTTATTAAAAAAGCCTATTTAAAGGGCTATTTCTGTAGACAGA
AGTTCAGTCTAGATTTAGGCCATCTCTAGGTTACAAGATGATAGGAGGTTAGACAAAAGTGATTCTTTTGCCAATGGGTGGTGGCATTGA
TTTTTTTCCTCCATGCATCTTGCCCAGGATCACTCAGTCAAGCATGTCTTCATCAAGTGGAAGCCAACTGTCCTGCCTGCCTCAAGAATA
TGTGTTTTCTTTAGCTTCCCTGAGGCTTTTTGGTGGTTCAGAAATAGGTGTGTGTGTTGATGTGTTTTTGGTAACCTAGCTTTCATACAC
ATAATATATGATTTATTAGAACTAGAGAATGTGTTTTCCCCGTTTGTTCATAAATGCGGTCGGTTATACTTCTTAGGTGACAGGTTATTG
TCCAGTACTTTAATGTATGTATGTATAATGGCTGTACAGGTAGACCATAATTCAGTCCTTTAGATTTATTTTATGCAGCAAAAAGAAGCT
CTTTTTTTTTTTTAATCACAAAAAAAAACCCCAGTTCAAAATGTGTAGTTCTTCATTGTTGGGTTGATTCCCCAAAACCTTGACAGATGT
ATCGATGGAATAAAAGTATGTTTTAAAGGTTACTTGAATGTCACAAAATTATGCCTTCATCAAAACTTTAAAGGAAAAATCAATTTATAA
AATCATGTAGGCCATTTTTATATTTGAAATTTGTCCTTTTAAAGATAGTTTTGCTGTTGCTCCTAGTGAAAGAAAAATCTCTGTACAAAG
GAGAAAAAGAACCCCACTTATTCTTAGTTAATACTAAAATATATAGCAATAAATTGCTGTTTATTTTTTCTACATCTATTTTGTGTACTT
GTACACAGTGTACATTCTTTTAAATTATATCGTGTATATAGCTTTAGTATTCGGTTACATGATTCACAGACCCCTGAATTCCAAAATATT
ATGGATAAACATTACCATTTATATGCTACAAATTAGTCTGATTCCATCTTTGAAAATGTCTTAAAGTATAAAATAATTAATTTGCTTTTT
TTTTTTTTTTTTCCCGAGATGGCGTCTTGCTGTGTCACCCAGGCTGGAGTGCAGTGGCACGATCTCAGCTCACTGCAGCCTCCTCCTCTT
GGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCCGCCACCATTCCGAGCTAATTTCTATATTTTTAGT
AAAGACGGGTTTCACCATTTTGGCCAGGTTGGTCTCGAACTCCTGACCTCAGGTGATCAGCCTGCTTTAGCCTCCCAGAGTGCTGGGATT
ACAGGCGTGAGCCACCGCACCCAGCCTAATTTGCCTTTTGATTCCTTCCCATTGTTGTCAACAATTAAGTCTATTCTTCTTTTAGAAATT
ATATGTAAATGATATTATTGATACTCTTTCTAAATAAGAGGTTTTAAAATATATAAAAACTTTATGATCCAATTATAGATAAATTTTCTA
ACATTTCCCAGTCACTAGGGTTTTATAAGTTGATTAAACATCAAATCAGAATCTAGCCAAGCAGGAATTATATTGAAATAAGTTCACATT
ACAGAAAAGGTTCCATAATTTGGCCAAACTGCATGCATGTAATGCTTATTTAGTAATGGTCACTGTATGTTAGATAAGGATAAAAATATA
TTTGTGAATTACTTCTGAGGAAATGCTAACTTCCACAGCATTGTATTTAATTATAACAATAACAGGAACATTAAATCTTTATCTTTGCTG
TTTCACCTCAAAGTCATAGATCATCTGGCTTTTTAGGCACCTTCACTAAAGGCAAAAATCTGATTTGTAGTTTTTATTAGCATGTACCTT
GAAATTATTTGACCAAGAAGCTCAAAGAAAAGAAGTACGTTAAAGAAAAAGAAAAAACCTCACTTTTCCTTTATAGTGTCCCTTCCTGTT
TTAATTCCTAAAGATCCTGACTTTTATCTGAGGAAGTCTAGGTAGTTTTCCTTTTGGATCTGGCCATTGGTGCGTGTTTCATTCAGATCA
CCTCTGGAATCTCTGTGGTTGTGAAGGCAATTCCTTATGAGACTCTTGCCTCCTGTGGCTTACGTGATGAATTGTTAATATGGCAGTAAT
TAATTAGTATCTACTTAAATTTAGTGGTCAGAAATGTATTTGAAGTGCCTTAAAGATGATCATGGTTCAGAATATCTTCAGAGAAAGCAA
AATCTTTAATATTGCAGGGAGCCTAGCAATACAAGTACACATTTCTGTGGCTTGATTTCTTGAATATGCTGAGACCCAATTTGGACTACA
TTTGGCAGAAATGATGGAGTAAACAGCAAGGCTTTAAATTAAATTAATAGTTACAAGGTAGGTTGGCTCTTAGGTGAATTTAGCCATGTC
AACTAATAGCTTTTATATGGTATGTAACAAATCTGAATTATGTTATGCTGTGAATTATTCAGTGCATTATAAGAAATCTTAGTTAATCAT
GCTTTTGGGCTTCATTAGTCAATGTGATTGGCCTTTTATTTTCTTTCCATAACTTATCTGCTATTATTAGTTTCTTATTCCTTATTATTA
ATCTGTTAGCTCATTATCATTAGCTTACTAACTTGAAAGTTAGATTAATATCAAAATAAGAATAGCAGCACTATGAAGAGTTAATAAAAT
GCAATTTCATGTTAGAGCTAGAATAAAAGTAATTGAGCAGTCATTTGCAAATGCTTCATTATAACATTTATGTGCTTAAGATTTCTAAGG
TTTTAAAAAGTTACCTTTAATACAATCCTTAGAAACTCAGAAATTTCCTGATATTCATTAGATTATGGTGTTTGCCTAATTTATACCGGT
TTTCACTGTATATTTTAATGAACTTTGATTGGTTACTTTTCCAGACATACAGATTTAATTTGGAATATGAACTTTGGTTCTTCATGAGTG
CATTTTGAAAAAGAAAAAAAGTACACATTCAGAATCTGGCCAATTTAAGTTTGTATTTTAAAAATATTTTATGCATGTTAAGTATGGTCG
CAGTAAATGAAATTGTGTTTAAGACTAAATTTACTACCGTTTTGAACAGACATTCCCAGATCATTCTTATATTGTCAGATAACACTTGTG
TATAATATCACTTTGGATCATGGACATGAGCTGGAAAAATGATGTATTTTTGTAGATTGTATGTCCAGAATGACTTTAGAACCGCATGAT
ACGGTGGAAGGAGCACTGGACTAGTCGTCACTACCCTTTTTGGATTCAGGGCTCCTCACAATTAAAATGAGTGTAATGAAACAAGGTGAA
AATATAGAAGCATCCCTTTGTATACTGTTTTGCTACTTACAGTGTACTTGGCATTGCTTTATCTCACTGGATTCTCATGGTAGGATTTCT
GAGATCTTAATCTAAGCTCCAAAGTTGTCTACTTTTTTGATCCTAGGGTGCTCCTTTTGTTTTACAGAGCAGGGTCACTTGATTTGCTAG
CTGGTGGCAGAATTGGCACCATTACCCAGGTCTGACTGACCACCAGTCAGAGGCACTTTATTTGTATCATGAAATGATTTGAAATCATTG
TAAAGCAGCGAAGTCTGATAATGAATGCCAGCTTTCCTTGTGCTTTGATAACAAAGACTCCAAATATTCTGGAGAACCTGGATAAAAGTT
TGAAGGGCTAGATTGGGATTTGAAGACAAAATTGTAGGAAATCTTACATTTTTGCAATAACAAACATTAATGAAAGCAAAACATTATAAA
AGTAATTTTAATTCACCACATACTTATCAATTTCTTGATGCTTCCAAATGACATCTACAGATATGGTTTTGTGGACATCTTTTTCTGTTT
ACATAAATTTATCCACTTAAAATGTGATAATGTGGAGACAAAGCAAGATTTGATTACATAAACTTTTCTCTGCATTGGTCTTTTCACTAT
CTTATTTGCTAACTTTTCTTATTTTTCTTCAACCTCCCCACCCTCCATTTTTTGGATATTAAACAGGGAAAGCTTGCTACATTATAAAGA
TTGTTGGCACCATTTATTTTACACAAAGGCTAAAGGTTAACTTTTGGAAATGATGAGCTACTTTTATATATGTGTTTACTCATGCTTTGT
GATATTTCTGGATCATTCCAGTCATAAAGACTTATTACATGTACTATTTCTTGCTACCTGTGAAAAGGTATATTTTAAAGAATGTATAAC
CAACAGTCCATTTACTTTTTATTAGTATGTAGAGGATTTGTATCTAATTCATGAATGTAGTTTTACAGTAGTTTGTCATTGTAAATGGAG
CAAAGTACATTATCTTCTAAAATGTACATTATGTAAGAATTGTAAATATACTTAAGTAATTTGTATGCCAAAAAATTACAATAAGTCAAT

>99833_99833_1_XXYLT1-ACAP2_XXYLT1_chr3_194877178_ENST00000310380_ACAP2_chr3_195112876_ENST00000326793_length(amino acids)=1022AA_BP=261
MGLLRGGLPCARAMARLGAVRSHYCALLLAAALAVCAFYYLGSGRETFSSATKRLKEARAGAPAAPSPPALELARGSVAPAPGAKAKSLE
GGGAGPVDYHLLMMFTKAEHNAALQAKARVALRSLLRLAKFEAHEVLNLHFVSEEASREVAKGLLRELLPPAAGFKCKVIFHDVAVLTDK
LFPIVEAMQKHFSAGLGTYYSDSIFFLSVAMHQIMPKEILQIIQLDLDLKFKTNIRELFEEFDSFLPGAIIGIAREMQPVYRAALEEVEG
DVAELELKLDKLVKLCIAMIDTGKAFCVANKQFMNGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKED
LRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQG
YDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKTWNRRWFSIQNNQL
VYQKKFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSLD
SGNESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVIN
RVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKSSEEKRLSISKFGPGDQVRASAQSSVRSNDSGIQ
QSSDDGRESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVT
CEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQPG

--------------------------------------------------------------
>99833_99833_2_XXYLT1-ACAP2_XXYLT1_chr3_194877178_ENST00000355729_ACAP2_chr3_195112876_ENST00000326793_length(transcript)=7052nt_BP=176nt
ATGTGGCCACCTCGCTGCAAGGATCCAGGAAGGCAGAGTGCGGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACC
AACATCCGGGAGTTGTTTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGGCA
GCTTTGGAAGAAGTAGAAGGTGATGTGGCAGAATTGGAACTAAAACTTGATAAGCTTGTGAAACTTTGTATTGCAATGATTGATACTGGA
AAAGCCTTTTGTGTTGCAAATAAACAGTTCATGAATGGGATTCGAGACCTGGCTCAGTATTCTAGTAATGATGCTGTCGTTGAGACAAGT
TTGACCAAGTTTTCTGACAGTCTTCAAGAAATGATAAATTTTCACACAATCCTGTTTGACCAAACTCAGAGATCAATTAAGGCACAGCTT
CAGAACTTTGTTAAAGAAGATCTTAGAAAATTCAAAGATGCCAAGAAGCAATTCGAAAAAGTCAGTGAAGAAAAAGAAAATGCGTTAGTA
AAAAATGCCCAAGTACAAAGAAACAAACAACATGAAGTTGAAGAAGCCACCAACATTCTGACAGCAACAAGAAAATGTTTCCGACACATA
GCCCTCGATTATGTGCTTCAGATTAATGTTCTTCAATCAAAAAGGAGATCAGAAATCCTAAAATCAATGTTGTCATTTATGTATGCCCAT
TTGGCCTTCTTTCATCAAGGATATGATCTGTTTAGTGAACTTGGACCCTACATGAAGGATCTTGGTGCACAGTTGGATCGACTGGTTGTG
GATGCAGCAAAGGAGAAAAGAGAAATGGAGCAAAAACATTCCACCATTCAACAAAAGGATTTCTCCAGTGATGATTCTAAGTTAGAATAT
AACGTAGATGCTGCAAATGGCATAGTTATGGAAGGATATCTGTTCAAACGAGCCAGCAATGCCTTCAAAACTTGGAACAGGCGCTGGTTT
TCAATACAGAATAATCAGTTGGTTTACCAGAAAAAATTTAAGGATAATCCGACTGTGGTAGTTGAAGACCTCAGGCTTTGCACAGTGAAA
CATTGTGAAGACATAGAGCGACGATTCTGCTTTGAGGTGGTCTCGCCAACAAAAAGTTGCATGCTCCAGGCAGATTCCGAAAAGCTGCGC
CAGGCATGGATTAAGGCTGTTCAGACCAGTATTGCTACTGCTTATAGAGAGAAGGGTGATGAATCAGAGAAGCTGGATAAGAAATCATCT
CCATCCACAGGAAGCCTAGATTCTGGAAATGAGTCCAAAGAGAAATTATTGAAAGGAGAAAGTGCGCTTCAGCGGGTCCAGTGTATCCCT
GGCAATGCCAGCTGTTGTGACTGTGGCCTGGCAGATCCACGGTGGGCCAGCATCAACCTGGGCATCACCTTGTGTATCGAGTGCTCCGGA
ATTCACCGGAGCCTTGGGGTTCATTTTTCAAAAGTACGATCTTTAACTTTAGACACCTGGGAGCCAGAACTTTTAAAGCTTATGTGTGAG
TTGGGGAATGATGTTATAAATCGAGTTTATGAAGCTAATGTGGAAAAAATGGGAATAAAGAAACCCCAACCAGGACAAAGACAGGAGAAG
GAGGCATATATCAGAGCAAAATATGTGGAGAGGAAATTTGTGGATAAATATTCTATATCATTATCACCTCCTGAGCAGCAAAAAAAGTTT
GTCTCTAAAAGTTCTGAAGAAAAGAGGCTGAGCATTTCTAAATTTGGGCCAGGGGACCAAGTCAGAGCATCTGCCCAAAGTTCAGTCAGA
AGTAATGACAGTGGAATTCAGCAGAGCTCTGATGATGGAAGAGAATCTTTACCCTCCACGGTGTCAGCCAATAGTTTATATGAGCCTGAA
GGAGAAAGGCAAGATTCTTCTATGTTTCTTGACTCGAAACATCTTAATCCAGGACTTCAGCTTTATAGGGCGTCATATGAAAAAAACCTT
CCTAAAATGGCTGAGGCTTTGGCTCATGGTGCAGACGTGAACTGGGCCAATTCAGAGGAAAACAAAGCGACACCACTTATTCAGGCTGTA
TTAGGGGGCTCTTTGGTGACGTGTGAGTTCCTCCTACAGAATGGTGCTAATGTCAACCAAAGAGATGTCCAAGGGCGGGGACCATTGCAC
CATGCCACCGTCTTAGGGCACACAGGGCAGGTATGTTTATTCCTAAAACGAGGTGCCAATCAACATGCCACTGATGAAGAAGGGAAAGAC
CCTTTGAGCATAGCTGTGGAAGCAGCCAATGCTGATATAGTCACCTTGTTACGTTTAGCAAGAATGAATGAAGAGATGCGGGAATCAGAA
GGACTTTATGGACAGCCAGGTGATGAAACTTATCAGGACATATTTCGTGATTTTTCCCAAATGGCATCCAATAATCCAGAGAAACTAAAT
CGTTTCCAGCAAGATTCACAGAAATTCTGAATTTTTTTAAAAATGGGAAAATATGAAATCTGGTGACCCCCTAATGTATACAGCTAAAAA
ATCACAATTTTTTTACTGCTTTAATTCTACTTAATTTTGGTAGATATTGAATGGCTTGGAAAAGAGGTACCCATTCATATATTTATAAAT
TAAAACATAGTTATCTAGTAGTAGGAGAGGAACCTAGTTTAGGACCTCTTTTATTAAAAAAGCCTATTTAAAGGGCTATTTCTGTAGACA
GAAGTTCAGTCTAGATTTAGGCCATCTCTAGGTTACAAGATGATAGGAGGTTAGACAAAAGTGATTCTTTTGCCAATGGGTGGTGGCATT
GATTTTTTTCCTCCATGCATCTTGCCCAGGATCACTCAGTCAAGCATGTCTTCATCAAGTGGAAGCCAACTGTCCTGCCTGCCTCAAGAA
TATGTGTTTTCTTTAGCTTCCCTGAGGCTTTTTGGTGGTTCAGAAATAGGTGTGTGTGTTGATGTGTTTTTGGTAACCTAGCTTTCATAC
ACATAATATATGATTTATTAGAACTAGAGAATGTGTTTTCCCCGTTTGTTCATAAATGCGGTCGGTTATACTTCTTAGGTGACAGGTTAT
TGTCCAGTACTTTAATGTATGTATGTATAATGGCTGTACAGGTAGACCATAATTCAGTCCTTTAGATTTATTTTATGCAGCAAAAAGAAG
CTCTTTTTTTTTTTTAATCACAAAAAAAAACCCCAGTTCAAAATGTGTAGTTCTTCATTGTTGGGTTGATTCCCCAAAACCTTGACAGAT
GTATCGATGGAATAAAAGTATGTTTTAAAGGTTACTTGAATGTCACAAAATTATGCCTTCATCAAAACTTTAAAGGAAAAATCAATTTAT
AAAATCATGTAGGCCATTTTTATATTTGAAATTTGTCCTTTTAAAGATAGTTTTGCTGTTGCTCCTAGTGAAAGAAAAATCTCTGTACAA
AGGAGAAAAAGAACCCCACTTATTCTTAGTTAATACTAAAATATATAGCAATAAATTGCTGTTTATTTTTTCTACATCTATTTTGTGTAC
TTGTACACAGTGTACATTCTTTTAAATTATATCGTGTATATAGCTTTAGTATTCGGTTACATGATTCACAGACCCCTGAATTCCAAAATA
TTATGGATAAACATTACCATTTATATGCTACAAATTAGTCTGATTCCATCTTTGAAAATGTCTTAAAGTATAAAATAATTAATTTGCTTT
TTTTTTTTTTTTTTCCCGAGATGGCGTCTTGCTGTGTCACCCAGGCTGGAGTGCAGTGGCACGATCTCAGCTCACTGCAGCCTCCTCCTC
TTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCCGCCACCATTCCGAGCTAATTTCTATATTTTTA
GTAAAGACGGGTTTCACCATTTTGGCCAGGTTGGTCTCGAACTCCTGACCTCAGGTGATCAGCCTGCTTTAGCCTCCCAGAGTGCTGGGA
TTACAGGCGTGAGCCACCGCACCCAGCCTAATTTGCCTTTTGATTCCTTCCCATTGTTGTCAACAATTAAGTCTATTCTTCTTTTAGAAA
TTATATGTAAATGATATTATTGATACTCTTTCTAAATAAGAGGTTTTAAAATATATAAAAACTTTATGATCCAATTATAGATAAATTTTC
TAACATTTCCCAGTCACTAGGGTTTTATAAGTTGATTAAACATCAAATCAGAATCTAGCCAAGCAGGAATTATATTGAAATAAGTTCACA
TTACAGAAAAGGTTCCATAATTTGGCCAAACTGCATGCATGTAATGCTTATTTAGTAATGGTCACTGTATGTTAGATAAGGATAAAAATA
TATTTGTGAATTACTTCTGAGGAAATGCTAACTTCCACAGCATTGTATTTAATTATAACAATAACAGGAACATTAAATCTTTATCTTTGC
TGTTTCACCTCAAAGTCATAGATCATCTGGCTTTTTAGGCACCTTCACTAAAGGCAAAAATCTGATTTGTAGTTTTTATTAGCATGTACC
TTGAAATTATTTGACCAAGAAGCTCAAAGAAAAGAAGTACGTTAAAGAAAAAGAAAAAACCTCACTTTTCCTTTATAGTGTCCCTTCCTG
TTTTAATTCCTAAAGATCCTGACTTTTATCTGAGGAAGTCTAGGTAGTTTTCCTTTTGGATCTGGCCATTGGTGCGTGTTTCATTCAGAT
CACCTCTGGAATCTCTGTGGTTGTGAAGGCAATTCCTTATGAGACTCTTGCCTCCTGTGGCTTACGTGATGAATTGTTAATATGGCAGTA
ATTAATTAGTATCTACTTAAATTTAGTGGTCAGAAATGTATTTGAAGTGCCTTAAAGATGATCATGGTTCAGAATATCTTCAGAGAAAGC
AAAATCTTTAATATTGCAGGGAGCCTAGCAATACAAGTACACATTTCTGTGGCTTGATTTCTTGAATATGCTGAGACCCAATTTGGACTA
CATTTGGCAGAAATGATGGAGTAAACAGCAAGGCTTTAAATTAAATTAATAGTTACAAGGTAGGTTGGCTCTTAGGTGAATTTAGCCATG
TCAACTAATAGCTTTTATATGGTATGTAACAAATCTGAATTATGTTATGCTGTGAATTATTCAGTGCATTATAAGAAATCTTAGTTAATC
ATGCTTTTGGGCTTCATTAGTCAATGTGATTGGCCTTTTATTTTCTTTCCATAACTTATCTGCTATTATTAGTTTCTTATTCCTTATTAT
TAATCTGTTAGCTCATTATCATTAGCTTACTAACTTGAAAGTTAGATTAATATCAAAATAAGAATAGCAGCACTATGAAGAGTTAATAAA
ATGCAATTTCATGTTAGAGCTAGAATAAAAGTAATTGAGCAGTCATTTGCAAATGCTTCATTATAACATTTATGTGCTTAAGATTTCTAA
GGTTTTAAAAAGTTACCTTTAATACAATCCTTAGAAACTCAGAAATTTCCTGATATTCATTAGATTATGGTGTTTGCCTAATTTATACCG
GTTTTCACTGTATATTTTAATGAACTTTGATTGGTTACTTTTCCAGACATACAGATTTAATTTGGAATATGAACTTTGGTTCTTCATGAG
TGCATTTTGAAAAAGAAAAAAAGTACACATTCAGAATCTGGCCAATTTAAGTTTGTATTTTAAAAATATTTTATGCATGTTAAGTATGGT
CGCAGTAAATGAAATTGTGTTTAAGACTAAATTTACTACCGTTTTGAACAGACATTCCCAGATCATTCTTATATTGTCAGATAACACTTG
TGTATAATATCACTTTGGATCATGGACATGAGCTGGAAAAATGATGTATTTTTGTAGATTGTATGTCCAGAATGACTTTAGAACCGCATG
ATACGGTGGAAGGAGCACTGGACTAGTCGTCACTACCCTTTTTGGATTCAGGGCTCCTCACAATTAAAATGAGTGTAATGAAACAAGGTG
AAAATATAGAAGCATCCCTTTGTATACTGTTTTGCTACTTACAGTGTACTTGGCATTGCTTTATCTCACTGGATTCTCATGGTAGGATTT
CTGAGATCTTAATCTAAGCTCCAAAGTTGTCTACTTTTTTGATCCTAGGGTGCTCCTTTTGTTTTACAGAGCAGGGTCACTTGATTTGCT
AGCTGGTGGCAGAATTGGCACCATTACCCAGGTCTGACTGACCACCAGTCAGAGGCACTTTATTTGTATCATGAAATGATTTGAAATCAT
TGTAAAGCAGCGAAGTCTGATAATGAATGCCAGCTTTCCTTGTGCTTTGATAACAAAGACTCCAAATATTCTGGAGAACCTGGATAAAAG
TTTGAAGGGCTAGATTGGGATTTGAAGACAAAATTGTAGGAAATCTTACATTTTTGCAATAACAAACATTAATGAAAGCAAAACATTATA
AAAGTAATTTTAATTCACCACATACTTATCAATTTCTTGATGCTTCCAAATGACATCTACAGATATGGTTTTGTGGACATCTTTTTCTGT
TTACATAAATTTATCCACTTAAAATGTGATAATGTGGAGACAAAGCAAGATTTGATTACATAAACTTTTCTCTGCATTGGTCTTTTCACT
ATCTTATTTGCTAACTTTTCTTATTTTTCTTCAACCTCCCCACCCTCCATTTTTTGGATATTAAACAGGGAAAGCTTGCTACATTATAAA
GATTGTTGGCACCATTTATTTTACACAAAGGCTAAAGGTTAACTTTTGGAAATGATGAGCTACTTTTATATATGTGTTTACTCATGCTTT
GTGATATTTCTGGATCATTCCAGTCATAAAGACTTATTACATGTACTATTTCTTGCTACCTGTGAAAAGGTATATTTTAAAGAATGTATA
ACCAACAGTCCATTTACTTTTTATTAGTATGTAGAGGATTTGTATCTAATTCATGAATGTAGTTTTACAGTAGTTTGTCATTGTAAATGG
AGCAAAGTACATTATCTTCTAAAATGTACATTATGTAAGAATTGTAAATATACTTAAGTAATTTGTATGCCAAAAAATTACAATAAGTCA

>99833_99833_2_XXYLT1-ACAP2_XXYLT1_chr3_194877178_ENST00000355729_ACAP2_chr3_195112876_ENST00000326793_length(amino acids)=819AA_BP=58
MWPPRCKDPGRQSAEILQIIQLDLDLKFKTNIRELFEEFDSFLPGAIIGIAREMQPVYRAALEEVEGDVAELELKLDKLVKLCIAMIDTG
KAFCVANKQFMNGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEKENALV
KNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVV
DAAKEKREMEQKHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQKKFKDNPTVVVEDLRLCTVK
HCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIP
GNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKPQPGQRQEK
EAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKSSEEKRLSISKFGPGDQVRASAQSSVRSNDSGIQQSSDDGRESLPSTVSANSLYEPE
GERQDSSMFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLH
HATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQPGDETYQDIFRDFSQMASNNPEKLN

--------------------------------------------------------------
>99833_99833_3_XXYLT1-ACAP2_XXYLT1_chr3_194877178_ENST00000429994_ACAP2_chr3_195112876_ENST00000326793_length(transcript)=7306nt_BP=430nt
GTGAGAGTCAGTGAGCTCTCAGGAGATCTGCTGTTTGAAAGTGTGTAGCGCTTCCCCCTTCTCTCTCTCTGTCCTGCTGCACTATGGTGA
GATGTGTCCCTTCCGCCGTGATTGTGTGTTTCCTGAGGCCTCCCCAGCCAGGCAGAACTGTCATCTTCCACGATGTTGCTGTGCTGACGG
ATAAGCTCTTCCCCATCGTGGAGGCCATGCAGAAGCACTTCAGTGCTGGCTTGGGAACCTACTACAGTGACTCCATCTTCTTCCTCTCGG
TCGCCATGCATCAGATCATGCCCAAAGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACCAACATCCGGGAGTTGT
TTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGGCAGCTTTGGAAGAAGTAG
AAGGTGATGTGGCAGAATTGGAACTAAAACTTGATAAGCTTGTGAAACTTTGTATTGCAATGATTGATACTGGAAAAGCCTTTTGTGTTG
CAAATAAACAGTTCATGAATGGGATTCGAGACCTGGCTCAGTATTCTAGTAATGATGCTGTCGTTGAGACAAGTTTGACCAAGTTTTCTG
ACAGTCTTCAAGAAATGATAAATTTTCACACAATCCTGTTTGACCAAACTCAGAGATCAATTAAGGCACAGCTTCAGAACTTTGTTAAAG
AAGATCTTAGAAAATTCAAAGATGCCAAGAAGCAATTCGAAAAAGTCAGTGAAGAAAAAGAAAATGCGTTAGTAAAAAATGCCCAAGTAC
AAAGAAACAAACAACATGAAGTTGAAGAAGCCACCAACATTCTGACAGCAACAAGAAAATGTTTCCGACACATAGCCCTCGATTATGTGC
TTCAGATTAATGTTCTTCAATCAAAAAGGAGATCAGAAATCCTAAAATCAATGTTGTCATTTATGTATGCCCATTTGGCCTTCTTTCATC
AAGGATATGATCTGTTTAGTGAACTTGGACCCTACATGAAGGATCTTGGTGCACAGTTGGATCGACTGGTTGTGGATGCAGCAAAGGAGA
AAAGAGAAATGGAGCAAAAACATTCCACCATTCAACAAAAGGATTTCTCCAGTGATGATTCTAAGTTAGAATATAACGTAGATGCTGCAA
ATGGCATAGTTATGGAAGGATATCTGTTCAAACGAGCCAGCAATGCCTTCAAAACTTGGAACAGGCGCTGGTTTTCAATACAGAATAATC
AGTTGGTTTACCAGAAAAAATTTAAGGATAATCCGACTGTGGTAGTTGAAGACCTCAGGCTTTGCACAGTGAAACATTGTGAAGACATAG
AGCGACGATTCTGCTTTGAGGTGGTCTCGCCAACAAAAAGTTGCATGCTCCAGGCAGATTCCGAAAAGCTGCGCCAGGCATGGATTAAGG
CTGTTCAGACCAGTATTGCTACTGCTTATAGAGAGAAGGGTGATGAATCAGAGAAGCTGGATAAGAAATCATCTCCATCCACAGGAAGCC
TAGATTCTGGAAATGAGTCCAAAGAGAAATTATTGAAAGGAGAAAGTGCGCTTCAGCGGGTCCAGTGTATCCCTGGCAATGCCAGCTGTT
GTGACTGTGGCCTGGCAGATCCACGGTGGGCCAGCATCAACCTGGGCATCACCTTGTGTATCGAGTGCTCCGGAATTCACCGGAGCCTTG
GGGTTCATTTTTCAAAAGTACGATCTTTAACTTTAGACACCTGGGAGCCAGAACTTTTAAAGCTTATGTGTGAGTTGGGGAATGATGTTA
TAAATCGAGTTTATGAAGCTAATGTGGAAAAAATGGGAATAAAGAAACCCCAACCAGGACAAAGACAGGAGAAGGAGGCATATATCAGAG
CAAAATATGTGGAGAGGAAATTTGTGGATAAATATTCTATATCATTATCACCTCCTGAGCAGCAAAAAAAGTTTGTCTCTAAAAGTTCTG
AAGAAAAGAGGCTGAGCATTTCTAAATTTGGGCCAGGGGACCAAGTCAGAGCATCTGCCCAAAGTTCAGTCAGAAGTAATGACAGTGGAA
TTCAGCAGAGCTCTGATGATGGAAGAGAATCTTTACCCTCCACGGTGTCAGCCAATAGTTTATATGAGCCTGAAGGAGAAAGGCAAGATT
CTTCTATGTTTCTTGACTCGAAACATCTTAATCCAGGACTTCAGCTTTATAGGGCGTCATATGAAAAAAACCTTCCTAAAATGGCTGAGG
CTTTGGCTCATGGTGCAGACGTGAACTGGGCCAATTCAGAGGAAAACAAAGCGACACCACTTATTCAGGCTGTATTAGGGGGCTCTTTGG
TGACGTGTGAGTTCCTCCTACAGAATGGTGCTAATGTCAACCAAAGAGATGTCCAAGGGCGGGGACCATTGCACCATGCCACCGTCTTAG
GGCACACAGGGCAGGTATGTTTATTCCTAAAACGAGGTGCCAATCAACATGCCACTGATGAAGAAGGGAAAGACCCTTTGAGCATAGCTG
TGGAAGCAGCCAATGCTGATATAGTCACCTTGTTACGTTTAGCAAGAATGAATGAAGAGATGCGGGAATCAGAAGGACTTTATGGACAGC
CAGGTGATGAAACTTATCAGGACATATTTCGTGATTTTTCCCAAATGGCATCCAATAATCCAGAGAAACTAAATCGTTTCCAGCAAGATT
CACAGAAATTCTGAATTTTTTTAAAAATGGGAAAATATGAAATCTGGTGACCCCCTAATGTATACAGCTAAAAAATCACAATTTTTTTAC
TGCTTTAATTCTACTTAATTTTGGTAGATATTGAATGGCTTGGAAAAGAGGTACCCATTCATATATTTATAAATTAAAACATAGTTATCT
AGTAGTAGGAGAGGAACCTAGTTTAGGACCTCTTTTATTAAAAAAGCCTATTTAAAGGGCTATTTCTGTAGACAGAAGTTCAGTCTAGAT
TTAGGCCATCTCTAGGTTACAAGATGATAGGAGGTTAGACAAAAGTGATTCTTTTGCCAATGGGTGGTGGCATTGATTTTTTTCCTCCAT
GCATCTTGCCCAGGATCACTCAGTCAAGCATGTCTTCATCAAGTGGAAGCCAACTGTCCTGCCTGCCTCAAGAATATGTGTTTTCTTTAG
CTTCCCTGAGGCTTTTTGGTGGTTCAGAAATAGGTGTGTGTGTTGATGTGTTTTTGGTAACCTAGCTTTCATACACATAATATATGATTT
ATTAGAACTAGAGAATGTGTTTTCCCCGTTTGTTCATAAATGCGGTCGGTTATACTTCTTAGGTGACAGGTTATTGTCCAGTACTTTAAT
GTATGTATGTATAATGGCTGTACAGGTAGACCATAATTCAGTCCTTTAGATTTATTTTATGCAGCAAAAAGAAGCTCTTTTTTTTTTTTA
ATCACAAAAAAAAACCCCAGTTCAAAATGTGTAGTTCTTCATTGTTGGGTTGATTCCCCAAAACCTTGACAGATGTATCGATGGAATAAA
AGTATGTTTTAAAGGTTACTTGAATGTCACAAAATTATGCCTTCATCAAAACTTTAAAGGAAAAATCAATTTATAAAATCATGTAGGCCA
TTTTTATATTTGAAATTTGTCCTTTTAAAGATAGTTTTGCTGTTGCTCCTAGTGAAAGAAAAATCTCTGTACAAAGGAGAAAAAGAACCC
CACTTATTCTTAGTTAATACTAAAATATATAGCAATAAATTGCTGTTTATTTTTTCTACATCTATTTTGTGTACTTGTACACAGTGTACA
TTCTTTTAAATTATATCGTGTATATAGCTTTAGTATTCGGTTACATGATTCACAGACCCCTGAATTCCAAAATATTATGGATAAACATTA
CCATTTATATGCTACAAATTAGTCTGATTCCATCTTTGAAAATGTCTTAAAGTATAAAATAATTAATTTGCTTTTTTTTTTTTTTTTTCC
CGAGATGGCGTCTTGCTGTGTCACCCAGGCTGGAGTGCAGTGGCACGATCTCAGCTCACTGCAGCCTCCTCCTCTTGGGTTCAAGCAATT
CTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCCGCCACCATTCCGAGCTAATTTCTATATTTTTAGTAAAGACGGGTTTCA
CCATTTTGGCCAGGTTGGTCTCGAACTCCTGACCTCAGGTGATCAGCCTGCTTTAGCCTCCCAGAGTGCTGGGATTACAGGCGTGAGCCA
CCGCACCCAGCCTAATTTGCCTTTTGATTCCTTCCCATTGTTGTCAACAATTAAGTCTATTCTTCTTTTAGAAATTATATGTAAATGATA
TTATTGATACTCTTTCTAAATAAGAGGTTTTAAAATATATAAAAACTTTATGATCCAATTATAGATAAATTTTCTAACATTTCCCAGTCA
CTAGGGTTTTATAAGTTGATTAAACATCAAATCAGAATCTAGCCAAGCAGGAATTATATTGAAATAAGTTCACATTACAGAAAAGGTTCC
ATAATTTGGCCAAACTGCATGCATGTAATGCTTATTTAGTAATGGTCACTGTATGTTAGATAAGGATAAAAATATATTTGTGAATTACTT
CTGAGGAAATGCTAACTTCCACAGCATTGTATTTAATTATAACAATAACAGGAACATTAAATCTTTATCTTTGCTGTTTCACCTCAAAGT
CATAGATCATCTGGCTTTTTAGGCACCTTCACTAAAGGCAAAAATCTGATTTGTAGTTTTTATTAGCATGTACCTTGAAATTATTTGACC
AAGAAGCTCAAAGAAAAGAAGTACGTTAAAGAAAAAGAAAAAACCTCACTTTTCCTTTATAGTGTCCCTTCCTGTTTTAATTCCTAAAGA
TCCTGACTTTTATCTGAGGAAGTCTAGGTAGTTTTCCTTTTGGATCTGGCCATTGGTGCGTGTTTCATTCAGATCACCTCTGGAATCTCT
GTGGTTGTGAAGGCAATTCCTTATGAGACTCTTGCCTCCTGTGGCTTACGTGATGAATTGTTAATATGGCAGTAATTAATTAGTATCTAC
TTAAATTTAGTGGTCAGAAATGTATTTGAAGTGCCTTAAAGATGATCATGGTTCAGAATATCTTCAGAGAAAGCAAAATCTTTAATATTG
CAGGGAGCCTAGCAATACAAGTACACATTTCTGTGGCTTGATTTCTTGAATATGCTGAGACCCAATTTGGACTACATTTGGCAGAAATGA
TGGAGTAAACAGCAAGGCTTTAAATTAAATTAATAGTTACAAGGTAGGTTGGCTCTTAGGTGAATTTAGCCATGTCAACTAATAGCTTTT
ATATGGTATGTAACAAATCTGAATTATGTTATGCTGTGAATTATTCAGTGCATTATAAGAAATCTTAGTTAATCATGCTTTTGGGCTTCA
TTAGTCAATGTGATTGGCCTTTTATTTTCTTTCCATAACTTATCTGCTATTATTAGTTTCTTATTCCTTATTATTAATCTGTTAGCTCAT
TATCATTAGCTTACTAACTTGAAAGTTAGATTAATATCAAAATAAGAATAGCAGCACTATGAAGAGTTAATAAAATGCAATTTCATGTTA
GAGCTAGAATAAAAGTAATTGAGCAGTCATTTGCAAATGCTTCATTATAACATTTATGTGCTTAAGATTTCTAAGGTTTTAAAAAGTTAC
CTTTAATACAATCCTTAGAAACTCAGAAATTTCCTGATATTCATTAGATTATGGTGTTTGCCTAATTTATACCGGTTTTCACTGTATATT
TTAATGAACTTTGATTGGTTACTTTTCCAGACATACAGATTTAATTTGGAATATGAACTTTGGTTCTTCATGAGTGCATTTTGAAAAAGA
AAAAAAGTACACATTCAGAATCTGGCCAATTTAAGTTTGTATTTTAAAAATATTTTATGCATGTTAAGTATGGTCGCAGTAAATGAAATT
GTGTTTAAGACTAAATTTACTACCGTTTTGAACAGACATTCCCAGATCATTCTTATATTGTCAGATAACACTTGTGTATAATATCACTTT
GGATCATGGACATGAGCTGGAAAAATGATGTATTTTTGTAGATTGTATGTCCAGAATGACTTTAGAACCGCATGATACGGTGGAAGGAGC
ACTGGACTAGTCGTCACTACCCTTTTTGGATTCAGGGCTCCTCACAATTAAAATGAGTGTAATGAAACAAGGTGAAAATATAGAAGCATC
CCTTTGTATACTGTTTTGCTACTTACAGTGTACTTGGCATTGCTTTATCTCACTGGATTCTCATGGTAGGATTTCTGAGATCTTAATCTA
AGCTCCAAAGTTGTCTACTTTTTTGATCCTAGGGTGCTCCTTTTGTTTTACAGAGCAGGGTCACTTGATTTGCTAGCTGGTGGCAGAATT
GGCACCATTACCCAGGTCTGACTGACCACCAGTCAGAGGCACTTTATTTGTATCATGAAATGATTTGAAATCATTGTAAAGCAGCGAAGT
CTGATAATGAATGCCAGCTTTCCTTGTGCTTTGATAACAAAGACTCCAAATATTCTGGAGAACCTGGATAAAAGTTTGAAGGGCTAGATT
GGGATTTGAAGACAAAATTGTAGGAAATCTTACATTTTTGCAATAACAAACATTAATGAAAGCAAAACATTATAAAAGTAATTTTAATTC
ACCACATACTTATCAATTTCTTGATGCTTCCAAATGACATCTACAGATATGGTTTTGTGGACATCTTTTTCTGTTTACATAAATTTATCC
ACTTAAAATGTGATAATGTGGAGACAAAGCAAGATTTGATTACATAAACTTTTCTCTGCATTGGTCTTTTCACTATCTTATTTGCTAACT
TTTCTTATTTTTCTTCAACCTCCCCACCCTCCATTTTTTGGATATTAAACAGGGAAAGCTTGCTACATTATAAAGATTGTTGGCACCATT
TATTTTACACAAAGGCTAAAGGTTAACTTTTGGAAATGATGAGCTACTTTTATATATGTGTTTACTCATGCTTTGTGATATTTCTGGATC
ATTCCAGTCATAAAGACTTATTACATGTACTATTTCTTGCTACCTGTGAAAAGGTATATTTTAAAGAATGTATAACCAACAGTCCATTTA
CTTTTTATTAGTATGTAGAGGATTTGTATCTAATTCATGAATGTAGTTTTACAGTAGTTTGTCATTGTAAATGGAGCAAAGTACATTATC
TTCTAAAATGTACATTATGTAAGAATTGTAAATATACTTAAGTAATTTGTATGCCAAAAAATTACAATAAGTCAATAAAGATCTCACCTC

>99833_99833_3_XXYLT1-ACAP2_XXYLT1_chr3_194877178_ENST00000429994_ACAP2_chr3_195112876_ENST00000326793_length(amino acids)=881AA_BP=120
MSCCTMVRCVPSAVIVCFLRPPQPGRTVIFHDVAVLTDKLFPIVEAMQKHFSAGLGTYYSDSIFFLSVAMHQIMPKEILQIIQLDLDLKF
KTNIRELFEEFDSFLPGAIIGIAREMQPVYRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFMNGIRDLAQYSSNDAVVE
TSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFR
HIALDYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDDSKL
EYNVDAANGIVMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQKKFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEK
LRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIEC
SGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQK
KFVSKSSEEKRLSISKFGPGDQVRASAQSSVRSNDSGIQQSSDDGRESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEK
NLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEG

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Fusion Gene PPI Analysis for XXYLT1-ACAP2

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Hgene	XXYLT1	chr3:194877178	chr3:195112876	ENST00000310380	-	3	4	263_266	261.6666666666667	394.0	target proteins
Hgene	XXYLT1	chr3:194877178	chr3:195112876	ENST00000355729	-	2	3	263_266	58.666666666666664	191.0	target proteins
Hgene	XXYLT1	chr3:194877178	chr3:195112876	ENST00000356740	-	1	2	263_266	0.0	188.0	target proteins
Hgene	XXYLT1	chr3:194877178	chr3:195112876	ENST00000437101	-	4	5	263_266	58.666666666666664	191.0	target proteins
Hgene	XXYLT1	chr3:194991284	chr3:195066046	ENST00000310380	-	1	4	263_266	168.0	394.0	target proteins
Hgene	XXYLT1	chr3:194991284	chr3:195066046	ENST00000355729	-	1	3	263_266	0.0	191.0	target proteins
Hgene	XXYLT1	chr3:194991284	chr3:195066046	ENST00000356740	-	1	2	263_266	0.0	188.0	target proteins
Hgene	XXYLT1	chr3:194991284	chr3:195066046	ENST00000437101	-	1	5	263_266	0	191.0	target proteins

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for XXYLT1-ACAP2

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for XXYLT1-ACAP2

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	XXYLT1	C0004238	Atrial Fibrillation	2	CTD_human
Hgene	XXYLT1	C0235480	Paroxysmal atrial fibrillation	2	CTD_human
Hgene	XXYLT1	C2585653	Persistent atrial fibrillation	2	CTD_human
Hgene	XXYLT1	C3468561	familial atrial fibrillation	2	CTD_human

Fusion Gene Studies in Kim Lab

Fusion gene:XXYLT1-ACAP2 (FusionGDB2 ID:HG152002TG23527)

Fusion Gene Summary for XXYLT1-ACAP2

Fusion Gene ORF analysis for XXYLT1-ACAP2

Fusion Genomic Features for XXYLT1-ACAP2

Fusion Protein Features for XXYLT1-ACAP2

Fusion Gene Sequence for XXYLT1-ACAP2

Fusion Gene PPI Analysis for XXYLT1-ACAP2

Related Drugs for XXYLT1-ACAP2

Related Diseases for XXYLT1-ACAP2

Fusion Gene Studies
in Kim Lab