|
Fusion Gene Summary | |
Fusion Gene ORF analysis | |
Fusion Genomic Features | |
Fusion Protein Features | |
Fusion Gene Sequence | |
Fusion Gene PPI analysis | |
Related Drugs | |
Related Diseases |
Fusion gene:CD55-UBE2G2 (FusionGDB2 ID:HG1604TG7327) |
Fusion Gene Summary for CD55-UBE2G2 |
Fusion gene summary |
Fusion gene information | Fusion gene name: CD55-UBE2G2 | Fusion gene ID: hg1604tg7327 | Hgene | Tgene | Gene symbol | CD55 | UBE2G2 | Gene ID | 1604 | 7327 |
Gene name | CD55 molecule (Cromer blood group) | ubiquitin conjugating enzyme E2 G2 | |
Synonyms | CHAPLE|CR|CROM|DAF|TC | UBC7 | |
Cytomap | ('CD55')('UBE2G2') 1q32.2 | 21q22.3 | |
Type of gene | protein-coding | protein-coding | |
Description | complement decay-accelerating factorCD55 antigenCD55 molecule, decay accelerating factor for complement (Cromer blood group)Cromer blood group antigen | ubiquitin-conjugating enzyme E2 G2E2 ubiquitin-conjugating enzyme G2ubiquitin carrier protein G2ubiquitin conjugating enzyme 7ubiquitin conjugating enzyme G2ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)ubiquitin-conjugating enzyme E2G 2 ( | |
Modification date | 20200313 | 20200313 | |
UniProtAcc | . | . | |
Ensembl transtripts involved in fusion gene | ENST00000367067, ENST00000465534, ENST00000314754, ENST00000367062, ENST00000367063, ENST00000367064, ENST00000367065, ENST00000391920, ENST00000391921, | ||
Fusion gene scores | * DoF score | 8 X 5 X 7=280 | 5 X 3 X 3=45 |
# samples | 9 | 5 | |
** MAII score | log2(9/280*10)=-1.63742992061529 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/45*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: CD55 [Title/Abstract] AND UBE2G2 [Title/Abstract] AND fusion [Title/Abstract] | ||
Most frequent breakpoint | CD55(207510754)-UBE2G2(46208010), # samples:1 | ||
Anticipated loss of major functional domain due to fusion event. | CD55-UBE2G2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CD55-UBE2G2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CD55-UBE2G2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CD55-UBE2G2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Partner | Gene | GO ID | GO term | PubMed ID |
Hgene | CD55 | GO:0007204 | positive regulation of cytosolic calcium ion concentration | 8223854 |
Hgene | CD55 | GO:0030449 | regulation of complement activation | 25284781 |
Hgene | CD55 | GO:0031664 | regulation of lipopolysaccharide-mediated signaling pathway | 12731067 |
Hgene | CD55 | GO:0035743 | CD4-positive, alpha-beta T cell cytokine production | 16818763 |
Hgene | CD55 | GO:0045916 | negative regulation of complement activation | 6211481 |
Hgene | CD55 | GO:1903659 | regulation of complement-dependent cytotoxicity | 25284781 |
Hgene | CD55 | GO:2000516 | positive regulation of CD4-positive, alpha-beta T cell activation | 16818763 |
Hgene | CD55 | GO:2000563 | positive regulation of CD4-positive, alpha-beta T cell proliferation | 16818763 |
Tgene | UBE2G2 | GO:0044257 | cellular protein catabolic process | 21628527 |
Tgene | UBE2G2 | GO:0070936 | protein K48-linked ubiquitination | 20061386 |
Fusion gene breakpoints across CD55 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene breakpoints across UBE2G2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChimerDB4 | OV | TCGA-57-1585 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
Top |
Fusion Gene ORF analysis for CD55-UBE2G2 |
Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
3UTR-3CDS | ENST00000367067 | ENST00000345496 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
3UTR-3CDS | ENST00000465534 | ENST00000345496 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
3UTR-5UTR | ENST00000367067 | ENST00000330942 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
3UTR-5UTR | ENST00000367067 | ENST00000477954 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
3UTR-5UTR | ENST00000465534 | ENST00000330942 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
3UTR-5UTR | ENST00000465534 | ENST00000477954 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
5CDS-5UTR | ENST00000314754 | ENST00000330942 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
5CDS-5UTR | ENST00000314754 | ENST00000477954 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
5CDS-5UTR | ENST00000367062 | ENST00000330942 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
5CDS-5UTR | ENST00000367062 | ENST00000477954 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
5CDS-5UTR | ENST00000367063 | ENST00000330942 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
5CDS-5UTR | ENST00000367063 | ENST00000477954 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
5CDS-5UTR | ENST00000367064 | ENST00000330942 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
5CDS-5UTR | ENST00000367064 | ENST00000477954 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
5CDS-5UTR | ENST00000367065 | ENST00000330942 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
5CDS-5UTR | ENST00000367065 | ENST00000477954 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
5CDS-5UTR | ENST00000391920 | ENST00000330942 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
5CDS-5UTR | ENST00000391920 | ENST00000477954 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
5CDS-5UTR | ENST00000391921 | ENST00000330942 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
5CDS-5UTR | ENST00000391921 | ENST00000477954 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
In-frame | ENST00000314754 | ENST00000345496 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
In-frame | ENST00000367062 | ENST00000345496 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
In-frame | ENST00000367063 | ENST00000345496 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
In-frame | ENST00000367064 | ENST00000345496 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
In-frame | ENST00000367065 | ENST00000345496 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
In-frame | ENST00000391920 | ENST00000345496 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
In-frame | ENST00000391921 | ENST00000345496 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - |
ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
ENST00000367064 | CD55 | chr1 | 207510754 | + | ENST00000345496 | UBE2G2 | chr21 | 46208010 | - | 4110 | 1318 | 81 | 1772 | 563 |
ENST00000367063 | CD55 | chr1 | 207510754 | + | ENST00000345496 | UBE2G2 | chr21 | 46208010 | - | 4086 | 1294 | 57 | 1748 | 563 |
ENST00000391921 | CD55 | chr1 | 207510754 | + | ENST00000345496 | UBE2G2 | chr21 | 46208010 | - | 3783 | 991 | 42 | 1445 | 467 |
ENST00000314754 | CD55 | chr1 | 207510754 | + | ENST00000345496 | UBE2G2 | chr21 | 46208010 | - | 3917 | 1125 | 65 | 1579 | 504 |
ENST00000391920 | CD55 | chr1 | 207510754 | + | ENST00000345496 | UBE2G2 | chr21 | 46208010 | - | 3870 | 1078 | 18 | 1532 | 504 |
ENST00000367062 | CD55 | chr1 | 207510754 | + | ENST00000345496 | UBE2G2 | chr21 | 46208010 | - | 3870 | 1078 | 18 | 1532 | 504 |
ENST00000367065 | CD55 | chr1 | 207510754 | + | ENST00000345496 | UBE2G2 | chr21 | 46208010 | - | 3870 | 1078 | 18 | 1532 | 504 |
DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
ENST00000367064 | ENST00000345496 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - | 0.000278882 | 0.9997211 |
ENST00000367063 | ENST00000345496 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - | 0.000281873 | 0.9997181 |
ENST00000391921 | ENST00000345496 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - | 0.000386266 | 0.9996138 |
ENST00000314754 | ENST00000345496 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - | 0.000250136 | 0.99974984 |
ENST00000391920 | ENST00000345496 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - | 0.000242193 | 0.9997578 |
ENST00000367062 | ENST00000345496 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - | 0.000242193 | 0.9997578 |
ENST00000367065 | ENST00000345496 | CD55 | chr1 | 207510754 | + | UBE2G2 | chr21 | 46208010 | - | 0.000242193 | 0.9997578 |
Top |
Fusion Genomic Features for CD55-UBE2G2 |
FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
Top |
Fusion Protein Features for CD55-UBE2G2 |
Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:207510754/chr21:46208010) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
Main function of each fusion partner protein. (from UniProt) |
Hgene | Tgene |
. | . |
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000314754 | + | 8 | 11 | 287_356 | 353 | 441.0 | Compositional bias | Note=Ser/Thr-rich |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000367062 | + | 8 | 11 | 287_356 | 353 | 436.0 | Compositional bias | Note=Ser/Thr-rich |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000367064 | + | 8 | 10 | 287_356 | 353 | 382.0 | Compositional bias | Note=Ser/Thr-rich |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000367065 | + | 8 | 11 | 287_356 | 353 | 440.0 | Compositional bias | Note=Ser/Thr-rich |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000391920 | + | 8 | 11 | 287_356 | 353 | 456.0 | Compositional bias | Note=Ser/Thr-rich |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000314754 | + | 8 | 11 | 161_222 | 353 | 441.0 | Domain | Sushi 3 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000314754 | + | 8 | 11 | 223_285 | 353 | 441.0 | Domain | Sushi 4 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000314754 | + | 8 | 11 | 35_96 | 353 | 441.0 | Domain | Sushi 1 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000314754 | + | 8 | 11 | 96_160 | 353 | 441.0 | Domain | Sushi 2 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000367062 | + | 8 | 11 | 161_222 | 353 | 436.0 | Domain | Sushi 3 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000367062 | + | 8 | 11 | 223_285 | 353 | 436.0 | Domain | Sushi 4 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000367062 | + | 8 | 11 | 35_96 | 353 | 436.0 | Domain | Sushi 1 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000367062 | + | 8 | 11 | 96_160 | 353 | 436.0 | Domain | Sushi 2 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000367064 | + | 8 | 10 | 161_222 | 353 | 382.0 | Domain | Sushi 3 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000367064 | + | 8 | 10 | 223_285 | 353 | 382.0 | Domain | Sushi 4 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000367064 | + | 8 | 10 | 35_96 | 353 | 382.0 | Domain | Sushi 1 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000367064 | + | 8 | 10 | 96_160 | 353 | 382.0 | Domain | Sushi 2 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000367065 | + | 8 | 11 | 161_222 | 353 | 440.0 | Domain | Sushi 3 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000367065 | + | 8 | 11 | 223_285 | 353 | 440.0 | Domain | Sushi 4 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000367065 | + | 8 | 11 | 35_96 | 353 | 440.0 | Domain | Sushi 1 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000367065 | + | 8 | 11 | 96_160 | 353 | 440.0 | Domain | Sushi 2 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000391920 | + | 8 | 11 | 161_222 | 353 | 456.0 | Domain | Sushi 3 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000391920 | + | 8 | 11 | 223_285 | 353 | 456.0 | Domain | Sushi 4 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000391920 | + | 8 | 11 | 35_96 | 353 | 456.0 | Domain | Sushi 1 |
Hgene | CD55 | chr1:207510754 | chr21:46208010 | ENST00000391920 | + | 8 | 11 | 96_160 | 353 | 456.0 | Domain | Sushi 2 |
Tgene | UBE2G2 | chr1:207510754 | chr21:46208010 | ENST00000330942 | 1 | 7 | 4_164 | 0 | 138.0 | Domain | UBC core |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Tgene | UBE2G2 | chr1:207510754 | chr21:46208010 | ENST00000345496 | 0 | 6 | 4_164 | 14 | 166.0 | Domain | UBC core |
Top |
Fusion Gene Sequence for CD55-UBE2G2 |
For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
>14558_14558_1_CD55-UBE2G2_CD55_chr1_207510754_ENST00000314754_UBE2G2_chr21_46208010_ENST00000345496_length(transcript)=3917nt_BP=1125nt CCGCTGGGCGTAGCTGCGACTCGGCGGAGTCCCGGCGGCGCGTCCTTGTTCTAACCCGGCGCGCCATGACCGTCGCGCGGCCGAGCGTGC CCGCGGCGCTGCCCCTCCTCGGGGAGCTGCCCCGGCTGCTGCTGCTGGTGCTGTTGTGCCTGCCGGCCGTGTGGGGTGACTGTGGCCTTC CCCCAGATGTACCTAATGCCCAGCCAGCTTTGGAAGGCCGTACAAGTTTTCCCGAGGATACTGTAATAACGTACAAATGTGAAGAAAGCT TTGTGAAAATTCCTGGCGAGAAGGACTCAGTGATCTGCCTTAAGGGCAGTCAATGGTCAGATATTGAAGAGTTCTGCAATCGTAGCTGCG AGGTGCCAACAAGGCTAAATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTTCCAGTCGGTACTGTTGTGGAATATGAGT GCCGTCCAGGTTACAGAAGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTAAAATGGTCCACAGCAGTCGAATTTTGTA AAAAGAAATCATGCCCTAATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCT CATGTAACACAGGGTACAAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAG AGTGCAGAGAAATTTATTGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTG TAACGTATGCATGTAATAAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCC CACCACCTGAATGCAGAGGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAG TCTCACCAACTTCTCAGAAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGC ATTTTCATGAAACAACCCCAAATAAAGGAAGTGGAACCACTTCAGAATTAACACTGAATCCTCCGGAAGGAATTGTAGCAGGCCCCATGA ATGAAGAGAACTTTTTTGAATGGGAGGCATTGATCATGGGCCCAGAAGACACCTGCTTTGAGTTTGGTGTTTTTCCTGCCATCCTGAGTT TCCCACTTGATTACCCGTTAAGTCCCCCAAAGATGAGATTTACCTGTGAGATGTTTCATCCCAACATCTACCCTGATGGGAGAGTCTGCA TTTCCATCCTCCACGCGCCAGGCGATGACCCCATGGGCTACGAGAGCAGCGCGGAGCGGTGGAGTCCTGTGCAGAGTGTGGAGAAGATCC TGCTGTCGGTGGTGAGCATGCTGGCAGAGCCCAATGACGAAAGTGGAGCTAACGTGGATGCGTCCAAAATGTGGCGCGATGACCGGGAGC AGTTCTATAAGATTGCCAAGCAGATCGTCCAGAAGTCTCTGGGACTGTGAGACCTGGCCTCGCACAGGCGCGCACACACCGCCAAGCAGC TCAGCATTCTCCCCCGGCACACTTAGTGACAGTGATGCTCTGTGCTGGTACCAAACAAGGCAGACTTGCAAGAACCATGGCATCTTTTTT TTTTTTCAAACCTTTCCTACTTCAAACAGGCTTCTCTTCTGAAATGATGACTTAATGTCGAATATTGACAGCTTACTGCAGTTTTACAGT ATTCCTCACAAAGGGCTTCAGGTAGATTATCAGAGCTGTCAGCACTACCTCTCCCCGCTGAAACCAGCAGTTCATGGCTTCCTGTGGATT CCCTCCCTCCCTGGAGTGTTGAGGGGGTTGTACCTGCCAGACTTCCAGGGGACGATGGAATACCCAGAACGCTCCTTCTGAAGAAATGGG GCCCTGTAGCTGCAGCACAGGGGAAGGGCCCGGCACCCTTTCTGGGTCCTTCCTGGTTCCCTGTGGGCCCCATGAGGAGTCCATTACTTC CTTTCTTCCTTCATATTTTACAGGCAGATGCTTTTCTTATAATCTAATTACATCTTTTCATTTGTTATATATTACAAACCATCACACTTA GAAATACTTCCAGGAAATGCTTTTTTGAAGTGTGAATTAATAAGAAATGGGGTAAATAGAAAAGAAATTTATTGCTGATTGGCCAGGTGC GGTGGTTCGTGCCTGTAATCCCAGCTCTTTGGGAGGCCAAGGCAGGTAGATCACAAGGTCAGGAAATTGAGACCATCCTGGCTAATACAG TGAAACCCCATGTCTGCTAAAATTACAAAAAATTAGCTGGGCGTGGTGGTGCACGCCTGTAGTCTCAGCTACTCAGGAGGCTGAGGCAGG AGAATCGCTTGAACCCGGGAGGCAGAGGTAGCAGTGAGCTGAAGTCCCGCCACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCAGTCT CAAAAAGAAAAAAGAAATTTATTGCTGATCACAAGGACAGACAGTTTTTTCCCGACCATACTCATCAAAGATTTACGTTTGTATATTAGT AACTAGTGCATTACTAGAGCAGGTGCAGGTGAGGTCTTTAAAGTTTCAATGAAAGTTTCTTCTGGATCTACAGAAAAAATTTTTTTTTTT CAATCTAAAAACTGGAAATTCTAGGGTTTTTGTACATTTTGGATGCACTGGGAATTTATTAGCACAAAATCATTCTTTGCAACTCAAAAT TCAGAAGGGACTCTACCATATCTTAGCTCAGAGCACAGAGGAGTGCCTTATCCCCACACTTGACTGGGCTGTGGAGGTGGGCATGTGGGC CCCTGGGCCCAGGCTGGGGACAGAGCCCTTGTTTTGTGACTTAGGATTTTGATGTGGTTCCCATGTTCTCTAACAGGGCCAGCTGAGCAG CACAGGCCAGGAGGCCACAGTGTAAGCAATAACAGATCTGCCACATGCAGAAGCAAATATCAGGCCTGTCGCACACGGGCGGCATTTAAA TAGGAATTTCTATTTTTGAAATAAGGGATGGTCTATGAGGCATACAGTAGATTTGATGTGATCCTTTTCTCCCTCCCTTCCATAATGGAT CGTGGTCTGTGTGACTGAACCCACACAGAGTGTCATGGGTGACAGTTTCTGGTTGAAGTAGCTCCACGCCTGGCTTCTGTGGACAGCAGA TTCTTTTCCTTCTCACAAGGGGCTCATTTAAAATTTGGAGGCTGGGTGCTGTGGCTCACGCCTGCAATCCCAGCACTTTGGGAGACTGAG GCGGGCGGATCATGAGGTCAGGAGATCGCGACCATCCTGGCTAACAGTGAAACCCTGTCTCCACTAAAAATACAAAAAATTAGCCGGGCG TGGTGGCGGGCGCCTGTAGTCCCAGCTACTCTGAAGACTGAGGCAGGAGAATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCTGAG ATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAATGGAACGCAGGGCAAGAACTCG TATTTGGAAGGAGATGGGGGAAAGGAGCGGTATTATACCTATGTTGTATTTGCAGGCAAATGAGATGGAGCCCTCTCTGTAAAGAAGAGT CATTTGTGCAAGTAGACGGGGTCTGTGGGTGCAGGCCCTGGAGGGGCACACAATTGCCTGGAGGCTTCTGTGAGATCGGGAGAGGGAGGA GAGGCAGTCTCTTGACAAAATAAAGTATTTTTATTCATTTGTATTTATTAAATGAAAAAACAATCCCATGGTGTCCCTGTTGTGTGGTGG >14558_14558_1_CD55-UBE2G2_CD55_chr1_207510754_ENST00000314754_UBE2G2_chr21_46208010_ENST00000345496_length(amino acids)=504AA_BP=353 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDI EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVN NDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSELTLNPP EGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHAPGDDPMGYESSAERWS -------------------------------------------------------------- >14558_14558_2_CD55-UBE2G2_CD55_chr1_207510754_ENST00000367062_UBE2G2_chr21_46208010_ENST00000345496_length(transcript)=3870nt_BP=1078nt GTTCTAACCCGGCGCGCCATGACCGTCGCGCGGCCGAGCGTGCCCGCGGCGCTGCCCCTCCTCGGGGAGCTGCCCCGGCTGCTGCTGCTG GTGCTGTTGTGCCTGCCGGCCGTGTGGGGTGACTGTGGCCTTCCCCCAGATGTACCTAATGCCCAGCCAGCTTTGGAAGGCCGTACAAGT TTTCCCGAGGATACTGTAATAACGTACAAATGTGAAGAAAGCTTTGTGAAAATTCCTGGCGAGAAGGACTCAGTGATCTGCCTTAAGGGC AGTCAATGGTCAGATATTGAAGAGTTCTGCAATCGTAGCTGCGAGGTGCCAACAAGGCTAAATTCTGCATCCCTCAAACAGCCTTATATC ACTCAGAATTATTTTCCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGAAGAGAACCTTCTCTATCACCAAAACTAACT TGCCTTCAGAATTTAAAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCTAATCCGGGAGAAATACGAAATGGTCAGATT GATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTACAAATTATTTGGCTCGACTTCTAGTTTTTGT CTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTATTGTCCAGCACCACCACAAATTGACAATGGA ATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAATAAAGGATTCACCATGATTGGAGAGCACTCT ATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGAGGAAAATCTCTAACTTCCAAGGTCCCACCA ACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAGAAAACCACCACAAAAACCACCACACCAAAT GCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACCCCAAATAAAGGAAGTGGAACCACTTCAGAA TTAACACTGAATCCTCCGGAAGGAATTGTAGCAGGCCCCATGAATGAAGAGAACTTTTTTGAATGGGAGGCATTGATCATGGGCCCAGAA GACACCTGCTTTGAGTTTGGTGTTTTTCCTGCCATCCTGAGTTTCCCACTTGATTACCCGTTAAGTCCCCCAAAGATGAGATTTACCTGT GAGATGTTTCATCCCAACATCTACCCTGATGGGAGAGTCTGCATTTCCATCCTCCACGCGCCAGGCGATGACCCCATGGGCTACGAGAGC AGCGCGGAGCGGTGGAGTCCTGTGCAGAGTGTGGAGAAGATCCTGCTGTCGGTGGTGAGCATGCTGGCAGAGCCCAATGACGAAAGTGGA GCTAACGTGGATGCGTCCAAAATGTGGCGCGATGACCGGGAGCAGTTCTATAAGATTGCCAAGCAGATCGTCCAGAAGTCTCTGGGACTG TGAGACCTGGCCTCGCACAGGCGCGCACACACCGCCAAGCAGCTCAGCATTCTCCCCCGGCACACTTAGTGACAGTGATGCTCTGTGCTG GTACCAAACAAGGCAGACTTGCAAGAACCATGGCATCTTTTTTTTTTTTCAAACCTTTCCTACTTCAAACAGGCTTCTCTTCTGAAATGA TGACTTAATGTCGAATATTGACAGCTTACTGCAGTTTTACAGTATTCCTCACAAAGGGCTTCAGGTAGATTATCAGAGCTGTCAGCACTA CCTCTCCCCGCTGAAACCAGCAGTTCATGGCTTCCTGTGGATTCCCTCCCTCCCTGGAGTGTTGAGGGGGTTGTACCTGCCAGACTTCCA GGGGACGATGGAATACCCAGAACGCTCCTTCTGAAGAAATGGGGCCCTGTAGCTGCAGCACAGGGGAAGGGCCCGGCACCCTTTCTGGGT CCTTCCTGGTTCCCTGTGGGCCCCATGAGGAGTCCATTACTTCCTTTCTTCCTTCATATTTTACAGGCAGATGCTTTTCTTATAATCTAA TTACATCTTTTCATTTGTTATATATTACAAACCATCACACTTAGAAATACTTCCAGGAAATGCTTTTTTGAAGTGTGAATTAATAAGAAA TGGGGTAAATAGAAAAGAAATTTATTGCTGATTGGCCAGGTGCGGTGGTTCGTGCCTGTAATCCCAGCTCTTTGGGAGGCCAAGGCAGGT AGATCACAAGGTCAGGAAATTGAGACCATCCTGGCTAATACAGTGAAACCCCATGTCTGCTAAAATTACAAAAAATTAGCTGGGCGTGGT GGTGCACGCCTGTAGTCTCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAGAGGTAGCAGTGAGCTGAAGTCC CGCCACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCAGTCTCAAAAAGAAAAAAGAAATTTATTGCTGATCACAAGGACAGACAGTTT TTTCCCGACCATACTCATCAAAGATTTACGTTTGTATATTAGTAACTAGTGCATTACTAGAGCAGGTGCAGGTGAGGTCTTTAAAGTTTC AATGAAAGTTTCTTCTGGATCTACAGAAAAAATTTTTTTTTTTCAATCTAAAAACTGGAAATTCTAGGGTTTTTGTACATTTTGGATGCA CTGGGAATTTATTAGCACAAAATCATTCTTTGCAACTCAAAATTCAGAAGGGACTCTACCATATCTTAGCTCAGAGCACAGAGGAGTGCC TTATCCCCACACTTGACTGGGCTGTGGAGGTGGGCATGTGGGCCCCTGGGCCCAGGCTGGGGACAGAGCCCTTGTTTTGTGACTTAGGAT TTTGATGTGGTTCCCATGTTCTCTAACAGGGCCAGCTGAGCAGCACAGGCCAGGAGGCCACAGTGTAAGCAATAACAGATCTGCCACATG CAGAAGCAAATATCAGGCCTGTCGCACACGGGCGGCATTTAAATAGGAATTTCTATTTTTGAAATAAGGGATGGTCTATGAGGCATACAG TAGATTTGATGTGATCCTTTTCTCCCTCCCTTCCATAATGGATCGTGGTCTGTGTGACTGAACCCACACAGAGTGTCATGGGTGACAGTT TCTGGTTGAAGTAGCTCCACGCCTGGCTTCTGTGGACAGCAGATTCTTTTCCTTCTCACAAGGGGCTCATTTAAAATTTGGAGGCTGGGT GCTGTGGCTCACGCCTGCAATCCCAGCACTTTGGGAGACTGAGGCGGGCGGATCATGAGGTCAGGAGATCGCGACCATCCTGGCTAACAG TGAAACCCTGTCTCCACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCTGAAGACTGAGGCAGG AGAATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCT CAAAAAAAAAAAAAAAAAAAATGGAACGCAGGGCAAGAACTCGTATTTGGAAGGAGATGGGGGAAAGGAGCGGTATTATACCTATGTTGT ATTTGCAGGCAAATGAGATGGAGCCCTCTCTGTAAAGAAGAGTCATTTGTGCAAGTAGACGGGGTCTGTGGGTGCAGGCCCTGGAGGGGC ACACAATTGCCTGGAGGCTTCTGTGAGATCGGGAGAGGGAGGAGAGGCAGTCTCTTGACAAAATAAAGTATTTTTATTCATTTGTATTTA TTAAATGAAAAAACAATCCCATGGTGTCCCTGTTGTGTGGTGGAACCTAATGACTGTTGAAATAAAGTTCTGTGTTTTCCCTGCCCTGCA >14558_14558_2_CD55-UBE2G2_CD55_chr1_207510754_ENST00000367062_UBE2G2_chr21_46208010_ENST00000345496_length(amino acids)=504AA_BP=353 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDI EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVN NDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSELTLNPP EGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHAPGDDPMGYESSAERWS -------------------------------------------------------------- >14558_14558_3_CD55-UBE2G2_CD55_chr1_207510754_ENST00000367063_UBE2G2_chr21_46208010_ENST00000345496_length(transcript)=4086nt_BP=1294nt GACGCCGGAGCCCTCTGACCGCACCTCTGACCACAACAAACCCCTACTCCACCCGTCTTGTTTGTCCCACCCTTGGTGACGCAGAGCCCC AGCCCAGACCCCGCCCAAAGCACTCATTTAACTGGTATTGCGGAGCCACGAGGCTTCTGCTTACTGCAACTCGCTCCGGCCGCTGGGCGT AGCTGCGACTCGGCGGAGTCCCGGCGGCGCGTCCTTGTTCTAACCCGGCGCGCCATGACCGTCGCGCGGCCGAGCGTGCCCGCGGCGCTG CCCCTCCTCGGGGAGCTGCCCCGGCTGCTGCTGCTGGTGCTGTTGTGCCTGCCGGCCGTGTGGGGTGACTGTGGCCTTCCCCCAGATGTA CCTAATGCCCAGCCAGCTTTGGAAGGCCGTACAAGTTTTCCCGAGGATACTGTAATAACGTACAAATGTGAAGAAAGCTTTGTGAAAATT CCTGGCGAGAAGGACTCAGTGATCTGCCTTAAGGGCAGTCAATGGTCAGATATTGAAGAGTTCTGCAATCGTAGCTGCGAGGTGCCAACA AGGCTAAATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTTCCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGT TACAGAAGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTAAAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCA TGCCCTAATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACA GGGTACAAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAA ATTTATTGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTGTAACGTATGCA TGTAATAAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAA TGCAGAGGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACT TCTCAGAAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAA ACAACCCCAAATAAAGGAAGTGGAACCACTTCAGAATTAACACTGAATCCTCCGGAAGGAATTGTAGCAGGCCCCATGAATGAAGAGAAC TTTTTTGAATGGGAGGCATTGATCATGGGCCCAGAAGACACCTGCTTTGAGTTTGGTGTTTTTCCTGCCATCCTGAGTTTCCCACTTGAT TACCCGTTAAGTCCCCCAAAGATGAGATTTACCTGTGAGATGTTTCATCCCAACATCTACCCTGATGGGAGAGTCTGCATTTCCATCCTC CACGCGCCAGGCGATGACCCCATGGGCTACGAGAGCAGCGCGGAGCGGTGGAGTCCTGTGCAGAGTGTGGAGAAGATCCTGCTGTCGGTG GTGAGCATGCTGGCAGAGCCCAATGACGAAAGTGGAGCTAACGTGGATGCGTCCAAAATGTGGCGCGATGACCGGGAGCAGTTCTATAAG ATTGCCAAGCAGATCGTCCAGAAGTCTCTGGGACTGTGAGACCTGGCCTCGCACAGGCGCGCACACACCGCCAAGCAGCTCAGCATTCTC CCCCGGCACACTTAGTGACAGTGATGCTCTGTGCTGGTACCAAACAAGGCAGACTTGCAAGAACCATGGCATCTTTTTTTTTTTTCAAAC CTTTCCTACTTCAAACAGGCTTCTCTTCTGAAATGATGACTTAATGTCGAATATTGACAGCTTACTGCAGTTTTACAGTATTCCTCACAA AGGGCTTCAGGTAGATTATCAGAGCTGTCAGCACTACCTCTCCCCGCTGAAACCAGCAGTTCATGGCTTCCTGTGGATTCCCTCCCTCCC TGGAGTGTTGAGGGGGTTGTACCTGCCAGACTTCCAGGGGACGATGGAATACCCAGAACGCTCCTTCTGAAGAAATGGGGCCCTGTAGCT GCAGCACAGGGGAAGGGCCCGGCACCCTTTCTGGGTCCTTCCTGGTTCCCTGTGGGCCCCATGAGGAGTCCATTACTTCCTTTCTTCCTT CATATTTTACAGGCAGATGCTTTTCTTATAATCTAATTACATCTTTTCATTTGTTATATATTACAAACCATCACACTTAGAAATACTTCC AGGAAATGCTTTTTTGAAGTGTGAATTAATAAGAAATGGGGTAAATAGAAAAGAAATTTATTGCTGATTGGCCAGGTGCGGTGGTTCGTG CCTGTAATCCCAGCTCTTTGGGAGGCCAAGGCAGGTAGATCACAAGGTCAGGAAATTGAGACCATCCTGGCTAATACAGTGAAACCCCAT GTCTGCTAAAATTACAAAAAATTAGCTGGGCGTGGTGGTGCACGCCTGTAGTCTCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTG AACCCGGGAGGCAGAGGTAGCAGTGAGCTGAAGTCCCGCCACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCAGTCTCAAAAAGAAAA AAGAAATTTATTGCTGATCACAAGGACAGACAGTTTTTTCCCGACCATACTCATCAAAGATTTACGTTTGTATATTAGTAACTAGTGCAT TACTAGAGCAGGTGCAGGTGAGGTCTTTAAAGTTTCAATGAAAGTTTCTTCTGGATCTACAGAAAAAATTTTTTTTTTTCAATCTAAAAA CTGGAAATTCTAGGGTTTTTGTACATTTTGGATGCACTGGGAATTTATTAGCACAAAATCATTCTTTGCAACTCAAAATTCAGAAGGGAC TCTACCATATCTTAGCTCAGAGCACAGAGGAGTGCCTTATCCCCACACTTGACTGGGCTGTGGAGGTGGGCATGTGGGCCCCTGGGCCCA GGCTGGGGACAGAGCCCTTGTTTTGTGACTTAGGATTTTGATGTGGTTCCCATGTTCTCTAACAGGGCCAGCTGAGCAGCACAGGCCAGG AGGCCACAGTGTAAGCAATAACAGATCTGCCACATGCAGAAGCAAATATCAGGCCTGTCGCACACGGGCGGCATTTAAATAGGAATTTCT ATTTTTGAAATAAGGGATGGTCTATGAGGCATACAGTAGATTTGATGTGATCCTTTTCTCCCTCCCTTCCATAATGGATCGTGGTCTGTG TGACTGAACCCACACAGAGTGTCATGGGTGACAGTTTCTGGTTGAAGTAGCTCCACGCCTGGCTTCTGTGGACAGCAGATTCTTTTCCTT CTCACAAGGGGCTCATTTAAAATTTGGAGGCTGGGTGCTGTGGCTCACGCCTGCAATCCCAGCACTTTGGGAGACTGAGGCGGGCGGATC ATGAGGTCAGGAGATCGCGACCATCCTGGCTAACAGTGAAACCCTGTCTCCACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGCGGGC GCCTGTAGTCCCAGCTACTCTGAAGACTGAGGCAGGAGAATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCTGAGATCACGCCACT GCACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAATGGAACGCAGGGCAAGAACTCGTATTTGGAAGG AGATGGGGGAAAGGAGCGGTATTATACCTATGTTGTATTTGCAGGCAAATGAGATGGAGCCCTCTCTGTAAAGAAGAGTCATTTGTGCAA GTAGACGGGGTCTGTGGGTGCAGGCCCTGGAGGGGCACACAATTGCCTGGAGGCTTCTGTGAGATCGGGAGAGGGAGGAGAGGCAGTCTC TTGACAAAATAAAGTATTTTTATTCATTTGTATTTATTAAATGAAAAAACAATCCCATGGTGTCCCTGTTGTGTGGTGGAACCTAATGAC >14558_14558_3_CD55-UBE2G2_CD55_chr1_207510754_ENST00000367063_UBE2G2_chr21_46208010_ENST00000345496_length(amino acids)=563AA_BP=412 MFVPPLVTQSPSPDPAQSTHLTGIAEPRGFCLLQLAPAAGRSCDSAESRRRVLVLTRRAMTVARPSVPAALPLLGELPRLLLLVLLCLPA VWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPV GTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSV QWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTT VNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSELTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEFG VFPAILSFPLDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLSVVSMLAEPNDESGANVDASK -------------------------------------------------------------- >14558_14558_4_CD55-UBE2G2_CD55_chr1_207510754_ENST00000367064_UBE2G2_chr21_46208010_ENST00000345496_length(transcript)=4110nt_BP=1318nt GAGTCTAGGGCCCCCGGGGCGTATGACGCCGGAGCCCTCTGACCGCACCTCTGACCACAACAAACCCCTACTCCACCCGTCTTGTTTGTC CCACCCTTGGTGACGCAGAGCCCCAGCCCAGACCCCGCCCAAAGCACTCATTTAACTGGTATTGCGGAGCCACGAGGCTTCTGCTTACTG CAACTCGCTCCGGCCGCTGGGCGTAGCTGCGACTCGGCGGAGTCCCGGCGGCGCGTCCTTGTTCTAACCCGGCGCGCCATGACCGTCGCG CGGCCGAGCGTGCCCGCGGCGCTGCCCCTCCTCGGGGAGCTGCCCCGGCTGCTGCTGCTGGTGCTGTTGTGCCTGCCGGCCGTGTGGGGT GACTGTGGCCTTCCCCCAGATGTACCTAATGCCCAGCCAGCTTTGGAAGGCCGTACAAGTTTTCCCGAGGATACTGTAATAACGTACAAA TGTGAAGAAAGCTTTGTGAAAATTCCTGGCGAGAAGGACTCAGTGATCTGCCTTAAGGGCAGTCAATGGTCAGATATTGAAGAGTTCTGC AATCGTAGCTGCGAGGTGCCAACAAGGCTAAATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTTCCAGTCGGTACTGTT GTGGAATATGAGTGCCGTCCAGGTTACAGAAGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTAAAATGGTCCACAGCA GTCGAATTTTGTAAAAAGAAATCATGCCCTAATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGCATATTATTTGGTGCA ACCATCTCCTTCTCATGTAACACAGGGTACAAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGCTCTGTCCAGTGGAGT GACCCGTTGCCAGAGTGCAGAGAAATTTATTGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAACGTGACCATTATGGA TATAGACAGTCTGTAACGTATGCATGTAATAAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTGAATAATGATGAAGGA GAGTGGAGTGGCCCACCACCTGAATGCAGAGGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCTACCACAGTAAATGTT CCAACTACAGAAGTCTCACCAACTTCTCAGAAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGGAGTACACCTGTTTCC AGGACAACCAAGCATTTTCATGAAACAACCCCAAATAAAGGAAGTGGAACCACTTCAGAATTAACACTGAATCCTCCGGAAGGAATTGTA GCAGGCCCCATGAATGAAGAGAACTTTTTTGAATGGGAGGCATTGATCATGGGCCCAGAAGACACCTGCTTTGAGTTTGGTGTTTTTCCT GCCATCCTGAGTTTCCCACTTGATTACCCGTTAAGTCCCCCAAAGATGAGATTTACCTGTGAGATGTTTCATCCCAACATCTACCCTGAT GGGAGAGTCTGCATTTCCATCCTCCACGCGCCAGGCGATGACCCCATGGGCTACGAGAGCAGCGCGGAGCGGTGGAGTCCTGTGCAGAGT GTGGAGAAGATCCTGCTGTCGGTGGTGAGCATGCTGGCAGAGCCCAATGACGAAAGTGGAGCTAACGTGGATGCGTCCAAAATGTGGCGC GATGACCGGGAGCAGTTCTATAAGATTGCCAAGCAGATCGTCCAGAAGTCTCTGGGACTGTGAGACCTGGCCTCGCACAGGCGCGCACAC ACCGCCAAGCAGCTCAGCATTCTCCCCCGGCACACTTAGTGACAGTGATGCTCTGTGCTGGTACCAAACAAGGCAGACTTGCAAGAACCA TGGCATCTTTTTTTTTTTTCAAACCTTTCCTACTTCAAACAGGCTTCTCTTCTGAAATGATGACTTAATGTCGAATATTGACAGCTTACT GCAGTTTTACAGTATTCCTCACAAAGGGCTTCAGGTAGATTATCAGAGCTGTCAGCACTACCTCTCCCCGCTGAAACCAGCAGTTCATGG CTTCCTGTGGATTCCCTCCCTCCCTGGAGTGTTGAGGGGGTTGTACCTGCCAGACTTCCAGGGGACGATGGAATACCCAGAACGCTCCTT CTGAAGAAATGGGGCCCTGTAGCTGCAGCACAGGGGAAGGGCCCGGCACCCTTTCTGGGTCCTTCCTGGTTCCCTGTGGGCCCCATGAGG AGTCCATTACTTCCTTTCTTCCTTCATATTTTACAGGCAGATGCTTTTCTTATAATCTAATTACATCTTTTCATTTGTTATATATTACAA ACCATCACACTTAGAAATACTTCCAGGAAATGCTTTTTTGAAGTGTGAATTAATAAGAAATGGGGTAAATAGAAAAGAAATTTATTGCTG ATTGGCCAGGTGCGGTGGTTCGTGCCTGTAATCCCAGCTCTTTGGGAGGCCAAGGCAGGTAGATCACAAGGTCAGGAAATTGAGACCATC CTGGCTAATACAGTGAAACCCCATGTCTGCTAAAATTACAAAAAATTAGCTGGGCGTGGTGGTGCACGCCTGTAGTCTCAGCTACTCAGG AGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAGAGGTAGCAGTGAGCTGAAGTCCCGCCACTGCACTCCAGCCTGGGCAACAGAG CGAGACTCAGTCTCAAAAAGAAAAAAGAAATTTATTGCTGATCACAAGGACAGACAGTTTTTTCCCGACCATACTCATCAAAGATTTACG TTTGTATATTAGTAACTAGTGCATTACTAGAGCAGGTGCAGGTGAGGTCTTTAAAGTTTCAATGAAAGTTTCTTCTGGATCTACAGAAAA AATTTTTTTTTTTCAATCTAAAAACTGGAAATTCTAGGGTTTTTGTACATTTTGGATGCACTGGGAATTTATTAGCACAAAATCATTCTT TGCAACTCAAAATTCAGAAGGGACTCTACCATATCTTAGCTCAGAGCACAGAGGAGTGCCTTATCCCCACACTTGACTGGGCTGTGGAGG TGGGCATGTGGGCCCCTGGGCCCAGGCTGGGGACAGAGCCCTTGTTTTGTGACTTAGGATTTTGATGTGGTTCCCATGTTCTCTAACAGG GCCAGCTGAGCAGCACAGGCCAGGAGGCCACAGTGTAAGCAATAACAGATCTGCCACATGCAGAAGCAAATATCAGGCCTGTCGCACACG GGCGGCATTTAAATAGGAATTTCTATTTTTGAAATAAGGGATGGTCTATGAGGCATACAGTAGATTTGATGTGATCCTTTTCTCCCTCCC TTCCATAATGGATCGTGGTCTGTGTGACTGAACCCACACAGAGTGTCATGGGTGACAGTTTCTGGTTGAAGTAGCTCCACGCCTGGCTTC TGTGGACAGCAGATTCTTTTCCTTCTCACAAGGGGCTCATTTAAAATTTGGAGGCTGGGTGCTGTGGCTCACGCCTGCAATCCCAGCACT TTGGGAGACTGAGGCGGGCGGATCATGAGGTCAGGAGATCGCGACCATCCTGGCTAACAGTGAAACCCTGTCTCCACTAAAAATACAAAA AATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCTGAAGACTGAGGCAGGAGAATGGCGTGAACCCAGGAGGCGGAGCTT GCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAATGGAACGCA GGGCAAGAACTCGTATTTGGAAGGAGATGGGGGAAAGGAGCGGTATTATACCTATGTTGTATTTGCAGGCAAATGAGATGGAGCCCTCTC TGTAAAGAAGAGTCATTTGTGCAAGTAGACGGGGTCTGTGGGTGCAGGCCCTGGAGGGGCACACAATTGCCTGGAGGCTTCTGTGAGATC GGGAGAGGGAGGAGAGGCAGTCTCTTGACAAAATAAAGTATTTTTATTCATTTGTATTTATTAAATGAAAAAACAATCCCATGGTGTCCC >14558_14558_4_CD55-UBE2G2_CD55_chr1_207510754_ENST00000367064_UBE2G2_chr21_46208010_ENST00000345496_length(amino acids)=563AA_BP=412 MFVPPLVTQSPSPDPAQSTHLTGIAEPRGFCLLQLAPAAGRSCDSAESRRRVLVLTRRAMTVARPSVPAALPLLGELPRLLLLVLLCLPA VWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPV GTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSV QWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTT VNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSELTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEFG VFPAILSFPLDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLSVVSMLAEPNDESGANVDASK -------------------------------------------------------------- >14558_14558_5_CD55-UBE2G2_CD55_chr1_207510754_ENST00000367065_UBE2G2_chr21_46208010_ENST00000345496_length(transcript)=3870nt_BP=1078nt GTTCTAACCCGGCGCGCCATGACCGTCGCGCGGCCGAGCGTGCCCGCGGCGCTGCCCCTCCTCGGGGAGCTGCCCCGGCTGCTGCTGCTG GTGCTGTTGTGCCTGCCGGCCGTGTGGGGTGACTGTGGCCTTCCCCCAGATGTACCTAATGCCCAGCCAGCTTTGGAAGGCCGTACAAGT TTTCCCGAGGATACTGTAATAACGTACAAATGTGAAGAAAGCTTTGTGAAAATTCCTGGCGAGAAGGACTCAGTGATCTGCCTTAAGGGC AGTCAATGGTCAGATATTGAAGAGTTCTGCAATCGTAGCTGCGAGGTGCCAACAAGGCTAAATTCTGCATCCCTCAAACAGCCTTATATC ACTCAGAATTATTTTCCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGAAGAGAACCTTCTCTATCACCAAAACTAACT TGCCTTCAGAATTTAAAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCTAATCCGGGAGAAATACGAAATGGTCAGATT GATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTACAAATTATTTGGCTCGACTTCTAGTTTTTGT CTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTATTGTCCAGCACCACCACAAATTGACAATGGA ATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAATAAAGGATTCACCATGATTGGAGAGCACTCT ATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGAGGAAAATCTCTAACTTCCAAGGTCCCACCA ACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAGAAAACCACCACAAAAACCACCACACCAAAT GCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACCCCAAATAAAGGAAGTGGAACCACTTCAGAA TTAACACTGAATCCTCCGGAAGGAATTGTAGCAGGCCCCATGAATGAAGAGAACTTTTTTGAATGGGAGGCATTGATCATGGGCCCAGAA GACACCTGCTTTGAGTTTGGTGTTTTTCCTGCCATCCTGAGTTTCCCACTTGATTACCCGTTAAGTCCCCCAAAGATGAGATTTACCTGT GAGATGTTTCATCCCAACATCTACCCTGATGGGAGAGTCTGCATTTCCATCCTCCACGCGCCAGGCGATGACCCCATGGGCTACGAGAGC AGCGCGGAGCGGTGGAGTCCTGTGCAGAGTGTGGAGAAGATCCTGCTGTCGGTGGTGAGCATGCTGGCAGAGCCCAATGACGAAAGTGGA GCTAACGTGGATGCGTCCAAAATGTGGCGCGATGACCGGGAGCAGTTCTATAAGATTGCCAAGCAGATCGTCCAGAAGTCTCTGGGACTG TGAGACCTGGCCTCGCACAGGCGCGCACACACCGCCAAGCAGCTCAGCATTCTCCCCCGGCACACTTAGTGACAGTGATGCTCTGTGCTG GTACCAAACAAGGCAGACTTGCAAGAACCATGGCATCTTTTTTTTTTTTCAAACCTTTCCTACTTCAAACAGGCTTCTCTTCTGAAATGA TGACTTAATGTCGAATATTGACAGCTTACTGCAGTTTTACAGTATTCCTCACAAAGGGCTTCAGGTAGATTATCAGAGCTGTCAGCACTA CCTCTCCCCGCTGAAACCAGCAGTTCATGGCTTCCTGTGGATTCCCTCCCTCCCTGGAGTGTTGAGGGGGTTGTACCTGCCAGACTTCCA GGGGACGATGGAATACCCAGAACGCTCCTTCTGAAGAAATGGGGCCCTGTAGCTGCAGCACAGGGGAAGGGCCCGGCACCCTTTCTGGGT CCTTCCTGGTTCCCTGTGGGCCCCATGAGGAGTCCATTACTTCCTTTCTTCCTTCATATTTTACAGGCAGATGCTTTTCTTATAATCTAA TTACATCTTTTCATTTGTTATATATTACAAACCATCACACTTAGAAATACTTCCAGGAAATGCTTTTTTGAAGTGTGAATTAATAAGAAA TGGGGTAAATAGAAAAGAAATTTATTGCTGATTGGCCAGGTGCGGTGGTTCGTGCCTGTAATCCCAGCTCTTTGGGAGGCCAAGGCAGGT AGATCACAAGGTCAGGAAATTGAGACCATCCTGGCTAATACAGTGAAACCCCATGTCTGCTAAAATTACAAAAAATTAGCTGGGCGTGGT GGTGCACGCCTGTAGTCTCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAGAGGTAGCAGTGAGCTGAAGTCC CGCCACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCAGTCTCAAAAAGAAAAAAGAAATTTATTGCTGATCACAAGGACAGACAGTTT TTTCCCGACCATACTCATCAAAGATTTACGTTTGTATATTAGTAACTAGTGCATTACTAGAGCAGGTGCAGGTGAGGTCTTTAAAGTTTC AATGAAAGTTTCTTCTGGATCTACAGAAAAAATTTTTTTTTTTCAATCTAAAAACTGGAAATTCTAGGGTTTTTGTACATTTTGGATGCA CTGGGAATTTATTAGCACAAAATCATTCTTTGCAACTCAAAATTCAGAAGGGACTCTACCATATCTTAGCTCAGAGCACAGAGGAGTGCC TTATCCCCACACTTGACTGGGCTGTGGAGGTGGGCATGTGGGCCCCTGGGCCCAGGCTGGGGACAGAGCCCTTGTTTTGTGACTTAGGAT TTTGATGTGGTTCCCATGTTCTCTAACAGGGCCAGCTGAGCAGCACAGGCCAGGAGGCCACAGTGTAAGCAATAACAGATCTGCCACATG CAGAAGCAAATATCAGGCCTGTCGCACACGGGCGGCATTTAAATAGGAATTTCTATTTTTGAAATAAGGGATGGTCTATGAGGCATACAG TAGATTTGATGTGATCCTTTTCTCCCTCCCTTCCATAATGGATCGTGGTCTGTGTGACTGAACCCACACAGAGTGTCATGGGTGACAGTT TCTGGTTGAAGTAGCTCCACGCCTGGCTTCTGTGGACAGCAGATTCTTTTCCTTCTCACAAGGGGCTCATTTAAAATTTGGAGGCTGGGT GCTGTGGCTCACGCCTGCAATCCCAGCACTTTGGGAGACTGAGGCGGGCGGATCATGAGGTCAGGAGATCGCGACCATCCTGGCTAACAG TGAAACCCTGTCTCCACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCTGAAGACTGAGGCAGG AGAATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCT CAAAAAAAAAAAAAAAAAAAATGGAACGCAGGGCAAGAACTCGTATTTGGAAGGAGATGGGGGAAAGGAGCGGTATTATACCTATGTTGT ATTTGCAGGCAAATGAGATGGAGCCCTCTCTGTAAAGAAGAGTCATTTGTGCAAGTAGACGGGGTCTGTGGGTGCAGGCCCTGGAGGGGC ACACAATTGCCTGGAGGCTTCTGTGAGATCGGGAGAGGGAGGAGAGGCAGTCTCTTGACAAAATAAAGTATTTTTATTCATTTGTATTTA TTAAATGAAAAAACAATCCCATGGTGTCCCTGTTGTGTGGTGGAACCTAATGACTGTTGAAATAAAGTTCTGTGTTTTCCCTGCCCTGCA >14558_14558_5_CD55-UBE2G2_CD55_chr1_207510754_ENST00000367065_UBE2G2_chr21_46208010_ENST00000345496_length(amino acids)=504AA_BP=353 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDI EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVN NDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSELTLNPP EGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHAPGDDPMGYESSAERWS -------------------------------------------------------------- >14558_14558_6_CD55-UBE2G2_CD55_chr1_207510754_ENST00000391920_UBE2G2_chr21_46208010_ENST00000345496_length(transcript)=3870nt_BP=1078nt GTTCTAACCCGGCGCGCCATGACCGTCGCGCGGCCGAGCGTGCCCGCGGCGCTGCCCCTCCTCGGGGAGCTGCCCCGGCTGCTGCTGCTG GTGCTGTTGTGCCTGCCGGCCGTGTGGGGTGACTGTGGCCTTCCCCCAGATGTACCTAATGCCCAGCCAGCTTTGGAAGGCCGTACAAGT TTTCCCGAGGATACTGTAATAACGTACAAATGTGAAGAAAGCTTTGTGAAAATTCCTGGCGAGAAGGACTCAGTGATCTGCCTTAAGGGC AGTCAATGGTCAGATATTGAAGAGTTCTGCAATCGTAGCTGCGAGGTGCCAACAAGGCTAAATTCTGCATCCCTCAAACAGCCTTATATC ACTCAGAATTATTTTCCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGAAGAGAACCTTCTCTATCACCAAAACTAACT TGCCTTCAGAATTTAAAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCTAATCCGGGAGAAATACGAAATGGTCAGATT GATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTACAAATTATTTGGCTCGACTTCTAGTTTTTGT CTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTATTGTCCAGCACCACCACAAATTGACAATGGA ATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAATAAAGGATTCACCATGATTGGAGAGCACTCT ATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGAGGAAAATCTCTAACTTCCAAGGTCCCACCA ACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAGAAAACCACCACAAAAACCACCACACCAAAT GCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACCCCAAATAAAGGAAGTGGAACCACTTCAGAA TTAACACTGAATCCTCCGGAAGGAATTGTAGCAGGCCCCATGAATGAAGAGAACTTTTTTGAATGGGAGGCATTGATCATGGGCCCAGAA GACACCTGCTTTGAGTTTGGTGTTTTTCCTGCCATCCTGAGTTTCCCACTTGATTACCCGTTAAGTCCCCCAAAGATGAGATTTACCTGT GAGATGTTTCATCCCAACATCTACCCTGATGGGAGAGTCTGCATTTCCATCCTCCACGCGCCAGGCGATGACCCCATGGGCTACGAGAGC AGCGCGGAGCGGTGGAGTCCTGTGCAGAGTGTGGAGAAGATCCTGCTGTCGGTGGTGAGCATGCTGGCAGAGCCCAATGACGAAAGTGGA GCTAACGTGGATGCGTCCAAAATGTGGCGCGATGACCGGGAGCAGTTCTATAAGATTGCCAAGCAGATCGTCCAGAAGTCTCTGGGACTG TGAGACCTGGCCTCGCACAGGCGCGCACACACCGCCAAGCAGCTCAGCATTCTCCCCCGGCACACTTAGTGACAGTGATGCTCTGTGCTG GTACCAAACAAGGCAGACTTGCAAGAACCATGGCATCTTTTTTTTTTTTCAAACCTTTCCTACTTCAAACAGGCTTCTCTTCTGAAATGA TGACTTAATGTCGAATATTGACAGCTTACTGCAGTTTTACAGTATTCCTCACAAAGGGCTTCAGGTAGATTATCAGAGCTGTCAGCACTA CCTCTCCCCGCTGAAACCAGCAGTTCATGGCTTCCTGTGGATTCCCTCCCTCCCTGGAGTGTTGAGGGGGTTGTACCTGCCAGACTTCCA GGGGACGATGGAATACCCAGAACGCTCCTTCTGAAGAAATGGGGCCCTGTAGCTGCAGCACAGGGGAAGGGCCCGGCACCCTTTCTGGGT CCTTCCTGGTTCCCTGTGGGCCCCATGAGGAGTCCATTACTTCCTTTCTTCCTTCATATTTTACAGGCAGATGCTTTTCTTATAATCTAA TTACATCTTTTCATTTGTTATATATTACAAACCATCACACTTAGAAATACTTCCAGGAAATGCTTTTTTGAAGTGTGAATTAATAAGAAA TGGGGTAAATAGAAAAGAAATTTATTGCTGATTGGCCAGGTGCGGTGGTTCGTGCCTGTAATCCCAGCTCTTTGGGAGGCCAAGGCAGGT AGATCACAAGGTCAGGAAATTGAGACCATCCTGGCTAATACAGTGAAACCCCATGTCTGCTAAAATTACAAAAAATTAGCTGGGCGTGGT GGTGCACGCCTGTAGTCTCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAGAGGTAGCAGTGAGCTGAAGTCC CGCCACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCAGTCTCAAAAAGAAAAAAGAAATTTATTGCTGATCACAAGGACAGACAGTTT TTTCCCGACCATACTCATCAAAGATTTACGTTTGTATATTAGTAACTAGTGCATTACTAGAGCAGGTGCAGGTGAGGTCTTTAAAGTTTC AATGAAAGTTTCTTCTGGATCTACAGAAAAAATTTTTTTTTTTCAATCTAAAAACTGGAAATTCTAGGGTTTTTGTACATTTTGGATGCA CTGGGAATTTATTAGCACAAAATCATTCTTTGCAACTCAAAATTCAGAAGGGACTCTACCATATCTTAGCTCAGAGCACAGAGGAGTGCC TTATCCCCACACTTGACTGGGCTGTGGAGGTGGGCATGTGGGCCCCTGGGCCCAGGCTGGGGACAGAGCCCTTGTTTTGTGACTTAGGAT TTTGATGTGGTTCCCATGTTCTCTAACAGGGCCAGCTGAGCAGCACAGGCCAGGAGGCCACAGTGTAAGCAATAACAGATCTGCCACATG CAGAAGCAAATATCAGGCCTGTCGCACACGGGCGGCATTTAAATAGGAATTTCTATTTTTGAAATAAGGGATGGTCTATGAGGCATACAG TAGATTTGATGTGATCCTTTTCTCCCTCCCTTCCATAATGGATCGTGGTCTGTGTGACTGAACCCACACAGAGTGTCATGGGTGACAGTT TCTGGTTGAAGTAGCTCCACGCCTGGCTTCTGTGGACAGCAGATTCTTTTCCTTCTCACAAGGGGCTCATTTAAAATTTGGAGGCTGGGT GCTGTGGCTCACGCCTGCAATCCCAGCACTTTGGGAGACTGAGGCGGGCGGATCATGAGGTCAGGAGATCGCGACCATCCTGGCTAACAG TGAAACCCTGTCTCCACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCTGAAGACTGAGGCAGG AGAATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCT CAAAAAAAAAAAAAAAAAAAATGGAACGCAGGGCAAGAACTCGTATTTGGAAGGAGATGGGGGAAAGGAGCGGTATTATACCTATGTTGT ATTTGCAGGCAAATGAGATGGAGCCCTCTCTGTAAAGAAGAGTCATTTGTGCAAGTAGACGGGGTCTGTGGGTGCAGGCCCTGGAGGGGC ACACAATTGCCTGGAGGCTTCTGTGAGATCGGGAGAGGGAGGAGAGGCAGTCTCTTGACAAAATAAAGTATTTTTATTCATTTGTATTTA TTAAATGAAAAAACAATCCCATGGTGTCCCTGTTGTGTGGTGGAACCTAATGACTGTTGAAATAAAGTTCTGTGTTTTCCCTGCCCTGCA >14558_14558_6_CD55-UBE2G2_CD55_chr1_207510754_ENST00000391920_UBE2G2_chr21_46208010_ENST00000345496_length(amino acids)=504AA_BP=353 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDI EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVN NDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSELTLNPP EGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHAPGDDPMGYESSAERWS -------------------------------------------------------------- >14558_14558_7_CD55-UBE2G2_CD55_chr1_207510754_ENST00000391921_UBE2G2_chr21_46208010_ENST00000345496_length(transcript)=3783nt_BP=991nt ACTCATTTAACTGGTATTGCGGAGCCACGAGGCTTCTGCTTACTGCAACTCGCTCCGGCCGCTGGGCGTAGCTGCGACTCGGCGGAGTCC CGGCGGCGCGTCCTTGTTCTAACCCGGCGCGCCATGACCGTCGCGCGGCCGAGCGTGCCCGCGGCGCTGCCCCTCCTCGGGGAGCTGCCC CGGCTGCTGCTGCTGGTGCTGTTGTGCCTGCCGGCCGTGTGGGGTGACTGTGGCCTTCCCCCAGATGTACCTAATGCCCAGCCAGCTTTG GAAGGCCGTACAAGTTTTCCCGAGGATACTGTAATAACGTACAAATGTGAAGAAAGCTTTGTGAAAATTCCTGGCGAGAAGGACTCAGTG ATCTGCCTTAAGGGCAGTCAATGGTCAGATATTGAAGAGTTCTGCAATCAGAAATCATGCCCTAATCCGGGAGAAATACGAAATGGTCAG ATTGATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTACAAATTATTTGGCTCGACTTCTAGTTTT TGTCTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTATTGTCCAGCACCACCACAAATTGACAAT GGAATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAATAAAGGATTCACCATGATTGGAGAGCAC TCTATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGAGGAAAATCTCTAACTTCCAAGGTCCCA CCAACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAGAAAACCACCACAAAAACCACCACACCA AATGCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACCCCAAATAAAGGAAGTGGAACCACTTCA GAATTAACACTGAATCCTCCGGAAGGAATTGTAGCAGGCCCCATGAATGAAGAGAACTTTTTTGAATGGGAGGCATTGATCATGGGCCCA GAAGACACCTGCTTTGAGTTTGGTGTTTTTCCTGCCATCCTGAGTTTCCCACTTGATTACCCGTTAAGTCCCCCAAAGATGAGATTTACC TGTGAGATGTTTCATCCCAACATCTACCCTGATGGGAGAGTCTGCATTTCCATCCTCCACGCGCCAGGCGATGACCCCATGGGCTACGAG AGCAGCGCGGAGCGGTGGAGTCCTGTGCAGAGTGTGGAGAAGATCCTGCTGTCGGTGGTGAGCATGCTGGCAGAGCCCAATGACGAAAGT GGAGCTAACGTGGATGCGTCCAAAATGTGGCGCGATGACCGGGAGCAGTTCTATAAGATTGCCAAGCAGATCGTCCAGAAGTCTCTGGGA CTGTGAGACCTGGCCTCGCACAGGCGCGCACACACCGCCAAGCAGCTCAGCATTCTCCCCCGGCACACTTAGTGACAGTGATGCTCTGTG CTGGTACCAAACAAGGCAGACTTGCAAGAACCATGGCATCTTTTTTTTTTTTCAAACCTTTCCTACTTCAAACAGGCTTCTCTTCTGAAA TGATGACTTAATGTCGAATATTGACAGCTTACTGCAGTTTTACAGTATTCCTCACAAAGGGCTTCAGGTAGATTATCAGAGCTGTCAGCA CTACCTCTCCCCGCTGAAACCAGCAGTTCATGGCTTCCTGTGGATTCCCTCCCTCCCTGGAGTGTTGAGGGGGTTGTACCTGCCAGACTT CCAGGGGACGATGGAATACCCAGAACGCTCCTTCTGAAGAAATGGGGCCCTGTAGCTGCAGCACAGGGGAAGGGCCCGGCACCCTTTCTG GGTCCTTCCTGGTTCCCTGTGGGCCCCATGAGGAGTCCATTACTTCCTTTCTTCCTTCATATTTTACAGGCAGATGCTTTTCTTATAATC TAATTACATCTTTTCATTTGTTATATATTACAAACCATCACACTTAGAAATACTTCCAGGAAATGCTTTTTTGAAGTGTGAATTAATAAG AAATGGGGTAAATAGAAAAGAAATTTATTGCTGATTGGCCAGGTGCGGTGGTTCGTGCCTGTAATCCCAGCTCTTTGGGAGGCCAAGGCA GGTAGATCACAAGGTCAGGAAATTGAGACCATCCTGGCTAATACAGTGAAACCCCATGTCTGCTAAAATTACAAAAAATTAGCTGGGCGT GGTGGTGCACGCCTGTAGTCTCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAGAGGTAGCAGTGAGCTGAAG TCCCGCCACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCAGTCTCAAAAAGAAAAAAGAAATTTATTGCTGATCACAAGGACAGACAG TTTTTTCCCGACCATACTCATCAAAGATTTACGTTTGTATATTAGTAACTAGTGCATTACTAGAGCAGGTGCAGGTGAGGTCTTTAAAGT TTCAATGAAAGTTTCTTCTGGATCTACAGAAAAAATTTTTTTTTTTCAATCTAAAAACTGGAAATTCTAGGGTTTTTGTACATTTTGGAT GCACTGGGAATTTATTAGCACAAAATCATTCTTTGCAACTCAAAATTCAGAAGGGACTCTACCATATCTTAGCTCAGAGCACAGAGGAGT GCCTTATCCCCACACTTGACTGGGCTGTGGAGGTGGGCATGTGGGCCCCTGGGCCCAGGCTGGGGACAGAGCCCTTGTTTTGTGACTTAG GATTTTGATGTGGTTCCCATGTTCTCTAACAGGGCCAGCTGAGCAGCACAGGCCAGGAGGCCACAGTGTAAGCAATAACAGATCTGCCAC ATGCAGAAGCAAATATCAGGCCTGTCGCACACGGGCGGCATTTAAATAGGAATTTCTATTTTTGAAATAAGGGATGGTCTATGAGGCATA CAGTAGATTTGATGTGATCCTTTTCTCCCTCCCTTCCATAATGGATCGTGGTCTGTGTGACTGAACCCACACAGAGTGTCATGGGTGACA GTTTCTGGTTGAAGTAGCTCCACGCCTGGCTTCTGTGGACAGCAGATTCTTTTCCTTCTCACAAGGGGCTCATTTAAAATTTGGAGGCTG GGTGCTGTGGCTCACGCCTGCAATCCCAGCACTTTGGGAGACTGAGGCGGGCGGATCATGAGGTCAGGAGATCGCGACCATCCTGGCTAA CAGTGAAACCCTGTCTCCACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCTGAAGACTGAGGC AGGAGAATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTG TCTCAAAAAAAAAAAAAAAAAAAATGGAACGCAGGGCAAGAACTCGTATTTGGAAGGAGATGGGGGAAAGGAGCGGTATTATACCTATGT TGTATTTGCAGGCAAATGAGATGGAGCCCTCTCTGTAAAGAAGAGTCATTTGTGCAAGTAGACGGGGTCTGTGGGTGCAGGCCCTGGAGG GGCACACAATTGCCTGGAGGCTTCTGTGAGATCGGGAGAGGGAGGAGAGGCAGTCTCTTGACAAAATAAAGTATTTTTATTCATTTGTAT TTATTAAATGAAAAAACAATCCCATGGTGTCCCTGTTGTGTGGTGGAACCTAATGACTGTTGAAATAAAGTTCTGTGTTTTCCCTGCCCT >14558_14558_7_CD55-UBE2G2_CD55_chr1_207510754_ENST00000391921_UBE2G2_chr21_46208010_ENST00000345496_length(amino acids)=467AA_BP=316 MQLAPAAGRSCDSAESRRRVLVLTRRAMTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITY KCEESFVKIPGEKDSVICLKGSQWSDIEEFCNQKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL PECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTT EVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSELTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAIL SFPLDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLSVVSMLAEPNDESGANVDASKMWRDDR -------------------------------------------------------------- |
Top |
Fusion Gene PPI Analysis for CD55-UBE2G2 |
Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
- Retained PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
- Lost PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
- Retained PPIs, but lost function due to frame-shift fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Related Drugs for CD55-UBE2G2 |
Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for CD55-UBE2G2 |
Diseases associated with fusion partners. (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | CD55 | C4538570 | COMPLEMENT HYPERACTIVATION, ANGIOPATHIC THROMBOSIS, AND PROTEIN-LOSING ENTEROPATHY | 2 | UNIPROT |
Hgene | CD55 | C0014175 | Endometriosis | 1 | CTD_human |
Hgene | CD55 | C0033680 | Protein-Losing Enteropathies | 1 | CTD_human;GENOMICS_ENGLAND |
Hgene | CD55 | C0086438 | Hypogammaglobulinemia | 1 | GENOMICS_ENGLAND |
Hgene | CD55 | C0236733 | Amphetamine-Related Disorders | 1 | CTD_human |
Hgene | CD55 | C0236804 | Amphetamine Addiction | 1 | CTD_human |
Hgene | CD55 | C0236807 | Amphetamine Abuse | 1 | CTD_human |
Hgene | CD55 | C0267372 | Primary intestinal lymphangiectasia | 1 | GENOMICS_ENGLAND |
Hgene | CD55 | C0269102 | Endometrioma | 1 | CTD_human |
Hgene | CD55 | C0272242 | Complement deficiency disease | 1 | GENOMICS_ENGLAND |