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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DCC-VEGFA (FusionGDB2 ID:HG1630TG7422)

Fusion Gene Summary for DCC-VEGFA

check button Fusion gene summary
Fusion gene informationFusion gene name: DCC-VEGFA
Fusion gene ID: hg1630tg7422
HgeneTgene
Gene symbol

DCC

VEGFA

Gene ID

1630

7422

Gene nameDCC netrin 1 receptorvascular endothelial growth factor A
SynonymsCRC18|CRCR1|HGPPS2|IGDCC1|MRMV1|NTN1R1MVCD1|VEGF|VPF
Cytomap('DCC')('VEGFA')

18q21.2

6p21.1

Type of geneprotein-codingprotein-coding
Descriptionnetrin receptor DCCcolorectal cancer suppressordeleted in colorectal carcinomaimmunoglobulin superfamily DCC subclass member 1putative colorectal tumor suppressortumor suppressor protein DCCvascular endothelial growth factor Avascular endothelial growth factor A121vascular endothelial growth factor A165vascular permeability factor
Modification date2020031320200329
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000412726, ENST00000442544, 
ENST00000580146, ENST00000581580, 
Fusion gene scores* DoF score9 X 9 X 2=16210 X 9 X 5=450
# samples 913
** MAII scorelog2(9/162*10)=-0.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(13/450*10)=-1.79141337818858
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DCC [Title/Abstract] AND VEGFA [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDCC(50549766)-VEGFA(43746273), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneVEGFA

GO:0000122

negative regulation of transcription by RNA polymerase II

18093989

TgeneVEGFA

GO:0001525

angiogenesis

11427521|21771332

TgeneVEGFA

GO:0001666

response to hypoxia

16490744

TgeneVEGFA

GO:0001934

positive regulation of protein phosphorylation

18386220|19033661

TgeneVEGFA

GO:0001938

positive regulation of endothelial cell proliferation

9202027|10022831|12714610|16489009|18386220|18577655|20497126

TgeneVEGFA

GO:0002042

cell migration involved in sprouting angiogenesis

18059339|20660291

TgeneVEGFA

GO:0002092

positive regulation of receptor internalization

20660291

TgeneVEGFA

GO:0008284

positive regulation of cell proliferation

7929439

TgeneVEGFA

GO:0008360

regulation of cell shape

7929439|10527820

TgeneVEGFA

GO:0010595

positive regulation of endothelial cell migration

10022831|19033661

TgeneVEGFA

GO:0010628

positive regulation of gene expression

18386220

TgeneVEGFA

GO:0010629

negative regulation of gene expression

28977001

TgeneVEGFA

GO:0010749

regulation of nitric oxide mediated signal transduction

16150726

TgeneVEGFA

GO:0030224

monocyte differentiation

21149635

TgeneVEGFA

GO:0030225

macrophage differentiation

21149635

TgeneVEGFA

GO:0030335

positive regulation of cell migration

7929439|17470632

TgeneVEGFA

GO:0030949

positive regulation of vascular endothelial growth factor receptor signaling pathway

1312256|7929439

TgeneVEGFA

GO:0031334

positive regulation of protein complex assembly

16489009|19033661

TgeneVEGFA

GO:0031954

positive regulation of protein autophosphorylation

20497126

TgeneVEGFA

GO:0032147

activation of protein kinase activity

18059339|20497126

TgeneVEGFA

GO:0032793

positive regulation of CREB transcription factor activity

20497126

TgeneVEGFA

GO:0033138

positive regulation of peptidyl-serine phosphorylation

18440775|20497126

TgeneVEGFA

GO:0035148

tube formation

19033661

TgeneVEGFA

GO:0035767

endothelial cell chemotaxis

18440775

TgeneVEGFA

GO:0035924

cellular response to vascular endothelial growth factor stimulus

18440775|20497126

TgeneVEGFA

GO:0038033

positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway

18440775|20497126|21245381

TgeneVEGFA

GO:0038091

positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway

17470632

TgeneVEGFA

GO:0042531

positive regulation of tyrosine phosphorylation of STAT protein

19390056

TgeneVEGFA

GO:0043117

positive regulation of vascular permeability

26598555

TgeneVEGFA

GO:0043154

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

18386220

TgeneVEGFA

GO:0043406

positive regulation of MAP kinase activity

18440775

TgeneVEGFA

GO:0043536

positive regulation of blood vessel endothelial cell migration

9202027|18440775|20497126

TgeneVEGFA

GO:0045766

positive regulation of angiogenesis

18440775|18577655|19033661|20497126

TgeneVEGFA

GO:0045785

positive regulation of cell adhesion

19674970

TgeneVEGFA

GO:0045944

positive regulation of transcription by RNA polymerase II

18059339

TgeneVEGFA

GO:0048010

vascular endothelial growth factor receptor signaling pathway

21245381

TgeneVEGFA

GO:0050731

positive regulation of peptidyl-tyrosine phosphorylation

10022831|16489009|20048167|21245381|26598555

TgeneVEGFA

GO:0050918

positive chemotaxis

20497126

TgeneVEGFA

GO:0050927

positive regulation of positive chemotaxis

7929439|12744932

TgeneVEGFA

GO:0051272

positive regulation of cellular component movement

10527820|12744932

TgeneVEGFA

GO:0051894

positive regulation of focal adhesion assembly

16489009

TgeneVEGFA

GO:0071456

cellular response to hypoxia

10575000

TgeneVEGFA

GO:0090037

positive regulation of protein kinase C signaling

18059339

TgeneVEGFA

GO:0090050

positive regulation of cell migration involved in sprouting angiogenesis

20551324

TgeneVEGFA

GO:0097533

cellular stress response to acid chemical

26299712

TgeneVEGFA

GO:1900086

positive regulation of peptidyl-tyrosine autophosphorylation

20660291

TgeneVEGFA

GO:1900745

positive regulation of p38MAPK cascade

18386220

TgeneVEGFA

GO:1901727

positive regulation of histone deacetylase activity

20497126

TgeneVEGFA

GO:1903141

negative regulation of establishment of endothelial barrier

20048167

TgeneVEGFA

GO:1903392

negative regulation of adherens junction organization

26598555

TgeneVEGFA

GO:1903572

positive regulation of protein kinase D signaling

20497126

TgeneVEGFA

GO:1903672

positive regulation of sprouting angiogenesis

26299712

TgeneVEGFA

GO:2000048

negative regulation of cell-cell adhesion mediated by cadherin

26598555



check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand


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Fusion Gene ORF analysis for DCC-VEGFA

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for DCC-VEGFA


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)


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Fusion Protein Features for DCC-VEGFA


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:50549766/:43746273)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for DCC-VEGFA


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for DCC-VEGFA


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DCC-VEGFA


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DCC-VEGFA


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneDCCC1834870MIRROR MOVEMENTS 12CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneDCCC0009402Colorectal Carcinoma1CTD_human;UNIPROT
HgeneDCCC0009404Colorectal Neoplasms1CTD_human
HgeneDCCC0020796Profound Mental Retardation1CTD_human
HgeneDCCC0025202melanoma1CTD_human
HgeneDCCC0025363Mental Retardation, Psychosocial1CTD_human
HgeneDCCC0036341Schizophrenia1PSYGENET
HgeneDCCC0162809Kallmann Syndrome1ORPHANET
HgeneDCCC0175754Agenesis of corpus callosum1CTD_human
HgeneDCCC0917816Mental deficiency1CTD_human
HgeneDCCC1846496Gaze Palsy, Familial Horizontal, with Progressive Scoliosis1ORPHANET
HgeneDCCC3179058Corpus Callosum Malformation1CTD_human
HgeneDCCC3714756Intellectual Disability1CTD_human
HgeneDCCC4479640GAZE PALSY, FAMILIAL HORIZONTAL, WITH PROGRESSIVE SCOLIOSIS, 21GENOMICS_ENGLAND;UNIPROT
HgeneDCCC4551964GAZE PALSY, FAMILIAL HORIZONTAL, WITH PROGRESSIVE SCOLIOSIS, 11CTD_human
TgeneC0011570Mental Depression5PSYGENET
TgeneC0011581Depressive disorder5PSYGENET
TgeneC0151744Myocardial Ischemia5CTD_human
TgeneC1269683Major Depressive Disorder5PSYGENET
TgeneC0033578Prostatic Neoplasms4CTD_human
TgeneC0376358Malignant neoplasm of prostate4CTD_human
TgeneC0004096Asthma3CTD_human
TgeneC0011884Diabetic Retinopathy3CTD_human
TgeneC0027627Neoplasm Metastasis3CTD_human
TgeneC0027659Neoplasms, Experimental3CTD_human
TgeneC0003865Arthritis, Adjuvant-Induced2CTD_human
TgeneC0005586Bipolar Disorder2PSYGENET
TgeneC0007137Squamous cell carcinoma2CTD_human
TgeneC0010054Coronary Arteriosclerosis2CTD_human
TgeneC0018801Heart failure2CTD_human
TgeneC0018802Congestive heart failure2CTD_human
TgeneC0022660Kidney Failure, Acute2CTD_human
TgeneC0023212Left-Sided Heart Failure2CTD_human
TgeneC0023893Liver Cirrhosis, Experimental2CTD_human
TgeneC0027686Pathologic Neovascularization2CTD_human
TgeneC0235527Heart Failure, Right-Sided2CTD_human
TgeneC0525045Mood Disorders2PSYGENET
TgeneC0971858Arthritis, Collagen-Induced2CTD_human
TgeneC0993582Arthritis, Experimental2CTD_human
TgeneC1565662Acute Kidney Insufficiency2CTD_human
TgeneC1956346Coronary Artery Disease2CTD_human
TgeneC1959583Myocardial Failure2CTD_human
TgeneC1961112Heart Decompensation2CTD_human
TgeneC2609414Acute kidney injury2CTD_human
TgeneC0001418Adenocarcinoma1CTD_human
TgeneC0002152Alloxan Diabetes1CTD_human
TgeneC0002395Alzheimer's Disease1CTD_human
TgeneC0003873Rheumatoid Arthritis1CTD_human
TgeneC0004153Atherosclerosis1CTD_human
TgeneC0006118Brain Neoplasms1CTD_human
TgeneC0006826Malignant Neoplasms1CTD_human
TgeneC0007102Malignant tumor of colon1CTD_human
TgeneC0007131Non-Small Cell Lung Carcinoma1CTD_human
TgeneC0007873Uterine Cervical Neoplasm1CTD_human
TgeneC0008677Bronchitis, Chronic1CTD_human
TgeneC0009375Colonic Neoplasms1CTD_human
TgeneC0010398Cruveilhier-Baumgarten Syndrome1CTD_human
TgeneC0011265Presenile dementia1CTD_human
TgeneC0011616Contact Dermatitis1CTD_human
TgeneC0011853Diabetes Mellitus, Experimental1CTD_human
TgeneC0011881Diabetic Nephropathy1CTD_human
TgeneC0013366Dyschondroplasias1CTD_human
TgeneC0014170Endometrial Neoplasms1CTD_human
TgeneC0014556Epilepsy, Temporal Lobe1CTD_human
TgeneC0014558Uncinate Epilepsy1CTD_human
TgeneC0017636Glioblastoma1CTD_human
TgeneC0017667Nodular glomerulosclerosis1CTD_human
TgeneC0018671Head and Neck Neoplasms1CTD_human
TgeneC0018675Head Neoplasms1CTD_human
TgeneC0018798Congenital Heart Defects1CTD_human
TgeneC0018799Heart Diseases1CTD_human
TgeneC0018923Hemangiosarcoma1CTD_human
TgeneC0019193Hepatitis, Toxic1CTD_human
TgeneC0020541Portal Hypertension1CTD_human
TgeneC0021368Inflammation1CTD_human
TgeneC0023186Learning Disorders1CTD_human
TgeneC0023466Leukemia, Monocytic, Chronic1CTD_human
TgeneC0023470Myeloid Leukemia1CTD_human
TgeneC0023890Liver Cirrhosis1CTD_human
TgeneC0024115Lung diseases1CTD_human
TgeneC0024440Macular Edema, Cystoid1CTD_human
TgeneC0025237Melnick-Needles Syndrome1CTD_human
TgeneC0025261Memory Disorders1CTD_human
TgeneC0026760Multiple Epiphyseal Dysplasia1CTD_human
TgeneC0027055Myocardial Reperfusion Injury1CTD_human
TgeneC0027533Neck Neoplasms1CTD_human
TgeneC0027643Neoplasm Recurrence, Local1CTD_human
TgeneC0027651Neoplasms1CTD_human
TgeneC0029422Osteochondrodysplasias1CTD_human
TgeneC0029463Osteosarcoma1CTD_human
TgeneC0030246Pustulosis of Palms and Soles1CTD_human
TgeneC0032927Precancerous Conditions1CTD_human
TgeneC0033687Proteinuria1CTD_human
TgeneC0033860Psoriasis1CTD_human
TgeneC0035228Respiratory Hypersensitivity1CTD_human
TgeneC0035309Retinal Diseases1CTD_human
TgeneC0035328Retinal Vein Occlusion1CTD_human
TgeneC0035412Rhabdomyosarcoma1CTD_human
TgeneC0036391Schwartz-Jampel Syndrome1CTD_human
TgeneC0038015Spondyloepiphyseal Dysplasia1CTD_human
TgeneC0038220Status Epilepticus1CTD_human
TgeneC0038358Gastric ulcer1CTD_human
TgeneC0038433Streptozotocin Diabetes1CTD_human
TgeneC0042076Urologic Neoplasms1CTD_human
TgeneC0085109Corneal Neovascularization1CTD_human
TgeneC0085605Liver Failure1CTD_human
TgeneC0086692Benign Neoplasm1CTD_human
TgeneC0153633Malignant neoplasm of brain1CTD_human
TgeneC0162351Contact hypersensitivity1CTD_human
TgeneC0178540Cerebral Hypoxia-Ischemia1CTD_human
TgeneC0205641Adenocarcinoma, Basal Cell1CTD_human
TgeneC0205642Adenocarcinoma, Oxyphilic1CTD_human
TgeneC0205643Carcinoma, Cribriform1CTD_human
TgeneC0205644Carcinoma, Granular Cell1CTD_human
TgeneC0205645Adenocarcinoma, Tubular1CTD_human
TgeneC0206726gliosarcoma1CTD_human
TgeneC0233794Memory impairment1CTD_human
TgeneC0239946Fibrosis, Liver1CTD_human
TgeneC0242350Erectile dysfunction1CTD_human
TgeneC0242383Age related macular degeneration1CTD_human
TgeneC0270823Petit mal status1CTD_human
TgeneC0271051Macular retinal edema1CTD_human
TgeneC0271178Irvine-Gass Syndrome1CTD_human
TgeneC0276496Familial Alzheimer Disease (FAD)1CTD_human
TgeneC0278996Malignant Head and Neck Neoplasm1CTD_human
TgeneC0282313Condition, Preneoplastic1CTD_human
TgeneC0311335Grand Mal Status Epilepticus1CTD_human
TgeneC0334588Giant Cell Glioblastoma1CTD_human
TgeneC0342257Complications of Diabetes Mellitus1CTD_human
TgeneC0393672Epilepsy, Benign Psychomotor, Childhood1CTD_human
TgeneC0393682Epilepsy, Lateral Temporal1CTD_human
TgeneC0393734Complex Partial Status Epilepticus1CTD_human
TgeneC0432272Van Buchem disease1CTD_human
TgeneC0476089Endometrial Carcinoma1CTD_human
TgeneC0494463Alzheimer Disease, Late Onset1CTD_human
TgeneC0496899Benign neoplasm of brain, unspecified1CTD_human
TgeneC0546126Acute Confusional Senile Dementia1CTD_human
TgeneC0600518Choroidal Neovascularization1CTD_human
TgeneC0678807prenatal alcohol exposure1PSYGENET
TgeneC0746787Cancer of Neck1CTD_human
TgeneC0750900Alzheimer's Disease, Focal Onset1CTD_human
TgeneC0750901Alzheimer Disease, Early Onset1CTD_human
TgeneC0750974Brain Tumor, Primary1CTD_human
TgeneC0750977Recurrent Brain Neoplasm1CTD_human
TgeneC0750979Primary malignant neoplasm of brain1CTD_human
TgeneC0751177Cancer of Head1CTD_human
TgeneC0751262Adult Learning Disorders1CTD_human
TgeneC0751263Learning Disturbance1CTD_human
TgeneC0751265Learning Disabilities1CTD_human
TgeneC0751292Age-Related Memory Disorders1CTD_human
TgeneC0751293Memory Disorder, Semantic1CTD_human
TgeneC0751294Memory Disorder, Spatial1CTD_human
TgeneC0751295Memory Loss1CTD_human
TgeneC0751522Status Epilepticus, Subclinical1CTD_human
TgeneC0751523Non-Convulsive Status Epilepticus1CTD_human
TgeneC0751524Simple Partial Status Epilepticus1CTD_human
TgeneC0751571Cancer of Urinary Tract1CTD_human
TgeneC0752304Hypoxic-Ischemic Encephalopathy1CTD_human
TgeneC0752305Anoxic-Ischemic Encephalopathy1CTD_human
TgeneC0752306Anoxia-Ischemia, Brain1CTD_human
TgeneC0752307Anoxia-Ischemia, Cerebral1CTD_human
TgeneC0752308Hypoxia-Ischemia, Brain1CTD_human
TgeneC0860207Drug-Induced Liver Disease1CTD_human
TgeneC0887833Carcinoma, Pancreatic Ductal1CTD_human
TgeneC0887900Upper Aerodigestive Tract Neoplasms1CTD_human
TgeneC1262760Hepatitis, Drug-Induced1CTD_human
TgeneC1330966Developmental Academic Disorder1CTD_human
TgeneC1527390Neoplasms, Intracranial1CTD_human
TgeneC1527411Thrombosis of retinal vein1CTD_human
TgeneC1563937Atherogenesis1CTD_human
TgeneC1621958Glioblastoma Multiforme1CTD_human
TgeneC2063866Depressive Disorder, Treatment-Resistant1PSYGENET
TgeneC2717961Thrombotic Microangiopathies1CTD_human
TgeneC2931852Clear-cell metastatic renal cell carcinoma1CTD_human
TgeneC2937358Cerebral Hemorrhage1CTD_human
TgeneC3541456Spondyloepiphyseal Dysplasia Tarda, X-Linked1CTD_human
TgeneC3658290Drug-Induced Acute Liver Injury1CTD_human
TgeneC4048328cervical cancer1CTD_human
TgeneC4277682Chemical and Drug Induced Liver Injury1CTD_human
TgeneC4279912Chemically-Induced Liver Toxicity1CTD_human
TgeneC4551479Schwartz-Jampel Syndrome, Type 11CTD_human