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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EML1-SPATA7 (FusionGDB2 ID:HG2009TG55812)

Fusion Gene Summary for EML1-SPATA7

check button Fusion gene summary
Fusion gene informationFusion gene name: EML1-SPATA7
Fusion gene ID: hg2009tg55812
HgeneTgene
Gene symbol

EML1

SPATA7

Gene ID

2009

55812

Gene nameEMAP like 1spermatogenesis associated 7
SynonymsBH|ELP79|EMAP|EMAP-1|EMAPLHEL-S-296|HSD-3.1|HSD3|LCA3
Cytomap('EML1')('SPATA7')

14q32.2

14q31.3

Type of geneprotein-codingprotein-coding
Descriptionechinoderm microtubule-associated protein-like 1echinoderm microtubule associated protein like 1spermatogenesis-associated protein 7epididymis secretory protein Li 296epididymis secretory sperm binding proteinspermatogenesis-associated protein HSD3
Modification date2020031320200328
UniProtAcc

O00423

.
Ensembl transtripts involved in fusion geneENST00000556758, ENST00000262233, 
ENST00000327921, ENST00000334192, 
Fusion gene scores* DoF score15 X 8 X 11=13203 X 4 X 3=36
# samples 174
** MAII scorelog2(17/1320*10)=-2.95693127810811
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: EML1 [Title/Abstract] AND SPATA7 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEML1(100317372)-SPATA7(88857725), # samples:1
Anticipated loss of major functional domain due to fusion event.EML1-SPATA7 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
EML1-SPATA7 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across EML1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across SPATA7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-E7-A85H-01AEML1chr14

100317372

-SPATA7chr14

88857725

+


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Fusion Gene ORF analysis for EML1-SPATA7

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000556758ENST00000356583EML1chr14

100317372

-SPATA7chr14

88857725

+
3UTR-3CDSENST00000556758ENST00000393545EML1chr14

100317372

-SPATA7chr14

88857725

+
3UTR-3CDSENST00000556758ENST00000556553EML1chr14

100317372

-SPATA7chr14

88857725

+
3UTR-3UTRENST00000556758ENST00000045347EML1chr14

100317372

-SPATA7chr14

88857725

+
3UTR-3UTRENST00000556758ENST00000554102EML1chr14

100317372

-SPATA7chr14

88857725

+
5CDS-3UTRENST00000262233ENST00000045347EML1chr14

100317372

-SPATA7chr14

88857725

+
5CDS-3UTRENST00000262233ENST00000554102EML1chr14

100317372

-SPATA7chr14

88857725

+
5CDS-3UTRENST00000327921ENST00000045347EML1chr14

100317372

-SPATA7chr14

88857725

+
5CDS-3UTRENST00000327921ENST00000554102EML1chr14

100317372

-SPATA7chr14

88857725

+
5CDS-3UTRENST00000334192ENST00000045347EML1chr14

100317372

-SPATA7chr14

88857725

+
5CDS-3UTRENST00000334192ENST00000554102EML1chr14

100317372

-SPATA7chr14

88857725

+
In-frameENST00000262233ENST00000356583EML1chr14

100317372

-SPATA7chr14

88857725

+
In-frameENST00000262233ENST00000393545EML1chr14

100317372

-SPATA7chr14

88857725

+
In-frameENST00000262233ENST00000556553EML1chr14

100317372

-SPATA7chr14

88857725

+
In-frameENST00000327921ENST00000356583EML1chr14

100317372

-SPATA7chr14

88857725

+
In-frameENST00000327921ENST00000393545EML1chr14

100317372

-SPATA7chr14

88857725

+
In-frameENST00000327921ENST00000556553EML1chr14

100317372

-SPATA7chr14

88857725

+
In-frameENST00000334192ENST00000356583EML1chr14

100317372

-SPATA7chr14

88857725

+
In-frameENST00000334192ENST00000393545EML1chr14

100317372

-SPATA7chr14

88857725

+
In-frameENST00000334192ENST00000556553EML1chr14

100317372

-SPATA7chr14

88857725

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000327921EML1chr14100317372-ENST00000556553SPATA7chr1488857725+297112489742932652
ENST00000327921EML1chr14100317372-ENST00000393545SPATA7chr1488857725+306312489743028684
ENST00000327921EML1chr14100317372-ENST00000356583SPATA7chr1488857725+296912489742932652
ENST00000262233EML1chr14100317372-ENST00000556553SPATA7chr1488857725+21123891392073644
ENST00000262233EML1chr14100317372-ENST00000393545SPATA7chr1488857725+22043891392169676
ENST00000262233EML1chr14100317372-ENST00000356583SPATA7chr1488857725+21103891392073644
ENST00000334192EML1chr14100317372-ENST00000556553SPATA7chr1488857725+21073841342068644
ENST00000334192EML1chr14100317372-ENST00000393545SPATA7chr1488857725+21993841342164676
ENST00000334192EML1chr14100317372-ENST00000356583SPATA7chr1488857725+21053841342068644

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000327921ENST00000556553EML1chr14100317372-SPATA7chr1488857725+0.0024952470.9975048
ENST00000327921ENST00000393545EML1chr14100317372-SPATA7chr1488857725+0.0021738620.99782616
ENST00000327921ENST00000356583EML1chr14100317372-SPATA7chr1488857725+0.0024991730.99750084
ENST00000262233ENST00000556553EML1chr14100317372-SPATA7chr1488857725+0.0019780740.99802196
ENST00000262233ENST00000393545EML1chr14100317372-SPATA7chr1488857725+0.0027005770.9972995
ENST00000262233ENST00000356583EML1chr14100317372-SPATA7chr1488857725+0.0019700520.9980299
ENST00000334192ENST00000556553EML1chr14100317372-SPATA7chr1488857725+0.0020774140.9979226
ENST00000334192ENST00000393545EML1chr14100317372-SPATA7chr1488857725+0.0028316010.99716836
ENST00000334192ENST00000356583EML1chr14100317372-SPATA7chr1488857725+0.0020695130.9979305

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Fusion Genomic Features for EML1-SPATA7


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for EML1-SPATA7


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:100317372/chr14:88857725)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EML1

O00423

.
FUNCTION: Modulates the assembly and organization of the microtubule cytoskeleton, and probably plays a role in regulating the orientation of the mitotic spindle and the orientation of the plane of cell division. Required for normal proliferation of neuronal progenitor cells in the developing brain and for normal brain development. Does not affect neuron migration per se. {ECO:0000250|UniProtKB:Q05BC3}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEML1chr14:100317372chr14:88857725ENST00000262233-222160_16683816.0Compositional biasNote=Poly-Ser
HgeneEML1chr14:100317372chr14:88857725ENST00000334192-223160_16683835.0Compositional biasNote=Poly-Ser
HgeneEML1chr14:100317372chr14:88857725ENST00000262233-222176_81583816.0RegionNote=Tandem atypical propeller in EMLs
HgeneEML1chr14:100317372chr14:88857725ENST00000334192-223176_81583835.0RegionNote=Tandem atypical propeller in EMLs
HgeneEML1chr14:100317372chr14:88857725ENST00000262233-222261_31083816.0RepeatNote=WD 1
HgeneEML1chr14:100317372chr14:88857725ENST00000262233-222315_35883816.0RepeatNote=WD 2
HgeneEML1chr14:100317372chr14:88857725ENST00000262233-222363_40083816.0RepeatNote=WD 3
HgeneEML1chr14:100317372chr14:88857725ENST00000262233-222409_44683816.0RepeatNote=WD 4
HgeneEML1chr14:100317372chr14:88857725ENST00000262233-222450_48983816.0RepeatNote=WD 5
HgeneEML1chr14:100317372chr14:88857725ENST00000262233-222493_53083816.0RepeatNote=WD 6
HgeneEML1chr14:100317372chr14:88857725ENST00000262233-222535_57283816.0RepeatNote=WD 7
HgeneEML1chr14:100317372chr14:88857725ENST00000262233-222578_61383816.0RepeatNote=WD 8
HgeneEML1chr14:100317372chr14:88857725ENST00000262233-222617_65583816.0RepeatNote=WD 9
HgeneEML1chr14:100317372chr14:88857725ENST00000262233-222664_70183816.0RepeatNote=WD 10
HgeneEML1chr14:100317372chr14:88857725ENST00000262233-222709_76883816.0RepeatNote=WD 11
HgeneEML1chr14:100317372chr14:88857725ENST00000262233-222775_81483816.0RepeatNote=WD 12
HgeneEML1chr14:100317372chr14:88857725ENST00000334192-223261_31083835.0RepeatNote=WD 1
HgeneEML1chr14:100317372chr14:88857725ENST00000334192-223315_35883835.0RepeatNote=WD 2
HgeneEML1chr14:100317372chr14:88857725ENST00000334192-223363_40083835.0RepeatNote=WD 3
HgeneEML1chr14:100317372chr14:88857725ENST00000334192-223409_44683835.0RepeatNote=WD 4
HgeneEML1chr14:100317372chr14:88857725ENST00000334192-223450_48983835.0RepeatNote=WD 5
HgeneEML1chr14:100317372chr14:88857725ENST00000334192-223493_53083835.0RepeatNote=WD 6
HgeneEML1chr14:100317372chr14:88857725ENST00000334192-223535_57283835.0RepeatNote=WD 7
HgeneEML1chr14:100317372chr14:88857725ENST00000334192-223578_61383835.0RepeatNote=WD 8
HgeneEML1chr14:100317372chr14:88857725ENST00000334192-223617_65583835.0RepeatNote=WD 9
HgeneEML1chr14:100317372chr14:88857725ENST00000334192-223664_70183835.0RepeatNote=WD 10
HgeneEML1chr14:100317372chr14:88857725ENST00000334192-223709_76883835.0RepeatNote=WD 11
HgeneEML1chr14:100317372chr14:88857725ENST00000334192-223775_81483835.0RepeatNote=WD 12


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Fusion Gene Sequence for EML1-SPATA7


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>26438_26438_1_EML1-SPATA7_EML1_chr14_100317372_ENST00000262233_SPATA7_chr14_88857725_ENST00000356583_length(transcript)=2110nt_BP=389nt
ATGGTAACCGGCAGCAGCAGCCGCCACAGCAGGGCCGGCCCCAGCGCCAGCGCCGGTCGCGGTCGGGCTCAGCTCAGTGTGTGGTGAGCG
GCGGCGGCGCGGCCGGGCCGGGGAGCGGGCGCGGCCCGGCGGCCTCAGCATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACAC
GTCCTCGCTGCTCCAGTTCTGCAACGATGACAGCGCTTCTGCTGCAAGTAGCATGGAGGTGACAGACCGCATTGCTTCACTGGAGCAGAG
AGTCCAGATGCAAGAAGACGACATCCAGCTGCTCAAATCAGCTCTAGCTGATGTGGTTCGGCGGCTGAACATTACTGAGGAACAGCAGGC
CGTGCTTAACAGGAAAGGACCTACCAAAGTCAGAGCAACCTCTGTCCTTCCCAGATATGGTCCACCGTGCCTATTTAAAGGACACTTGAG
CACCAAAAGTAATGCTGCAGTAGACTGCTCGGTTCCAGTAAGCGTGAGTACCAGCATAAAGTATGCAGACCAACAACGAAGAGAGAAACT
CAAAAAGGAATTAGCACAATGTGAAAAAGAGTTCAAATTAACTAAAACTGCAATGCGAGCCAATTATAAAAATAATTCCAAGTCACTTTT
TAATACCTTACAAAAGCCCTCAGGCGAACCGCAAATTGAGGATGACATGTTAAAAGAAGAAATGAATGGATTTTCATCCTTTGCAAGGTC
ACTAGTACCCTCTTCAGAGAGACTACACCTAAGTCTACATAAATCCAGTAAAGTCATCACAAATGGTCCTGAGAAGAACTCCAGTTCCTC
CCCGTCCAGTGTGGATTATGCAGCCTCCGGGCCCCGGAAACTGAGCTCTGGAGCCCTGTATGGCAGAAGGCCCAGAAGCACATTCCCAAA
TTCCCACCGGTTTCAGTTAGTCATTTCGAAAGCACCCAGTGGGGATCTTTTGGATAAACATTCTGAACTCTTTTCTAACAAACAATTGCC
ATTCACTCCTCGCACTTTAAAAACAGAAGCAAAATCTTTCCTGTCACAGTATCGCTATTATACACCTGCCAAAAGAAAAAAGGATTTTAC
AGATCAACGGATAGAAGCTGAAACCCAGACTGAATTAAGCTTTAAATCTGAGTTGGGGACAGCTGAGACTAAAAACATGACAGATTCAGA
AATGAACATAAAGCAGGCATCTAATTGTGTGACATATGATGCCAAAGAAAAAATAGCTCCTTTACCTTTAGAAGGGCATGACTCAACATG
GGATGAGATTAAGGATGATGCTCTTCAGCATTCCTCACCAAGGGCAATGTGTCAGTATTCCCTGAAGCCCCCTTCAACTCGTAAAATCTA
CTCTGATGAAGAAGAACTGTTGTATCTGAGTTTCATTGAAGATGTAACAGATGAAATTTTGAAACTTGGTTTATTTTCAAACAGGTTTTT
AGAACGACTGTTCGAGCGACATATAAAACAAAATAAACATTTGGAGGAGGAAAAAATGCGCCACCTGCTGCATGTCCTGAAAGTAGACTT
AGGCTGCACATCGGAGGAAAACTCGGTAAAGCAAAATGATGTTGATATGTTGAATGTATTTGATTTTGAAAAGGCTGGGAATTCAGAACC
AAATGAATTAAAAAATGAAAGTGAAGTAACAATTCAGCAGGAACGTCAACAATACCAAAAGGCTTTGGATATGTTATTGTCGGCACCAAA
GGATGAGAACGAGATATTCCCTTCACCAACTGAATTTTTCATGCCTATTTATAAATCAAAGCATTCAGAAGGGGTTATAATTCAACAGGT
GAATGATGAAACAAATCTTGAAACTTCAACTTTGGATGAAAATCATCCAAGTATTTCAGACAGTTTAACAGATCGGGAAACTTCTGTGAA
TGTCATTGAAGGTGATAGTGACCCTGAAAAGGTTGAGATTTCAAATGGATTATGTGGTCTTAACACATCACCCTCCCAATCTGTTCAGTT
CTCCAGTGTCAAAGGCGACAATAATCATGACATGGAGTTATCAACTCTTAAAATCATGGAAATGAGCATTGAGGACTGCCCTTTGGATGT
TTAATCTTCATTAATAAATACCTCAAATGGCCAGTAACTC

>26438_26438_1_EML1-SPATA7_EML1_chr14_100317372_ENST00000262233_SPATA7_chr14_88857725_ENST00000356583_length(amino acids)=644AA_BP=82
MEDGFSSYSSLYDTSSLLQFCNDDSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALADVVRRLNITEEQQAVLNRKGPTKVRATSVL
PRYGPPCLFKGHLSTKSNAAVDCSVPVSVSTSIKYADQQRREKLKKELAQCEKEFKLTKTAMRANYKNNSKSLFNTLQKPSGEPQIEDDM
LKEEMNGFSSFARSLVPSSERLHLSLHKSSKVITNGPEKNSSSSPSSVDYAASGPRKLSSGALYGRRPRSTFPNSHRFQLVISKAPSGDL
LDKHSELFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRKKDFTDQRIEAETQTELSFKSELGTAETKNMTDSEMNIKQASNCVTYDAKE
KIAPLPLEGHDSTWDEIKDDALQHSSPRAMCQYSLKPPSTRKIYSDEEELLYLSFIEDVTDEILKLGLFSNRFLERLFERHIKQNKHLEE
EKMRHLLHVLKVDLGCTSEENSVKQNDVDMLNVFDFEKAGNSEPNELKNESEVTIQQERQQYQKALDMLLSAPKDENEIFPSPTEFFMPI
YKSKHSEGVIIQQVNDETNLETSTLDENHPSISDSLTDRETSVNVIEGDSDPEKVEISNGLCGLNTSPSQSVQFSSVKGDNNHDMELSTL
KIMEMSIEDCPLDV

--------------------------------------------------------------
>26438_26438_2_EML1-SPATA7_EML1_chr14_100317372_ENST00000262233_SPATA7_chr14_88857725_ENST00000393545_length(transcript)=2204nt_BP=389nt
ATGGTAACCGGCAGCAGCAGCCGCCACAGCAGGGCCGGCCCCAGCGCCAGCGCCGGTCGCGGTCGGGCTCAGCTCAGTGTGTGGTGAGCG
GCGGCGGCGCGGCCGGGCCGGGGAGCGGGCGCGGCCCGGCGGCCTCAGCATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACAC
GTCCTCGCTGCTCCAGTTCTGCAACGATGACAGCGCTTCTGCTGCAAGTAGCATGGAGGTGACAGACCGCATTGCTTCACTGGAGCAGAG
AGTCCAGATGCAAGAAGACGACATCCAGCTGCTCAAATCAGCTCTAGCTGATGTGGTTCGGCGGCTGAACATTACTGAGGAACAGCAGGC
CGTGCTTAACAGGAAAGGACCTACCAAAGTCAGAGCAACCTCTGTCCTTCCCAGATATGGTCCACCGTGCCTATTTAAAGGACACTTGAG
CACCAAAAGTAATGCTTTTTGCACTGACTCCTCTTCTCTCAGACTAAGCACTCTCCAGCTGGTCAAGAATCACATGGCTGTTCACTATAA
TAAAATCCTTTCAGCCAAAGCTGCAGTAGACTGCTCGGTTCCAGTAAGCGTGAGTACCAGCATAAAGTATGCAGACCAACAACGAAGAGA
GAAACTCAAAAAGGAATTAGCACAATGTGAAAAAGAGTTCAAATTAACTAAAACTGCAATGCGAGCCAATTATAAAAATAATTCCAAGTC
ACTTTTTAATACCTTACAAAAGCCCTCAGGCGAACCGCAAATTGAGGATGACATGTTAAAAGAAGAAATGAATGGATTTTCATCCTTTGC
AAGGTCACTAGTACCCTCTTCAGAGAGACTACACCTAAGTCTACATAAATCCAGTAAAGTCATCACAAATGGTCCTGAGAAGAACTCCAG
TTCCTCCCCGTCCAGTGTGGATTATGCAGCCTCCGGGCCCCGGAAACTGAGCTCTGGAGCCCTGTATGGCAGAAGGCCCAGAAGCACATT
CCCAAATTCCCACCGGTTTCAGTTAGTCATTTCGAAAGCACCCAGTGGGGATCTTTTGGATAAACATTCTGAACTCTTTTCTAACAAACA
ATTGCCATTCACTCCTCGCACTTTAAAAACAGAAGCAAAATCTTTCCTGTCACAGTATCGCTATTATACACCTGCCAAAAGAAAAAAGGA
TTTTACAGATCAACGGATAGAAGCTGAAACCCAGACTGAATTAAGCTTTAAATCTGAGTTGGGGACAGCTGAGACTAAAAACATGACAGA
TTCAGAAATGAACATAAAGCAGGCATCTAATTGTGTGACATATGATGCCAAAGAAAAAATAGCTCCTTTACCTTTAGAAGGGCATGACTC
AACATGGGATGAGATTAAGGATGATGCTCTTCAGCATTCCTCACCAAGGGCAATGTGTCAGTATTCCCTGAAGCCCCCTTCAACTCGTAA
AATCTACTCTGATGAAGAAGAACTGTTGTATCTGAGTTTCATTGAAGATGTAACAGATGAAATTTTGAAACTTGGTTTATTTTCAAACAG
GTTTTTAGAACGACTGTTCGAGCGACATATAAAACAAAATAAACATTTGGAGGAGGAAAAAATGCGCCACCTGCTGCATGTCCTGAAAGT
AGACTTAGGCTGCACATCGGAGGAAAACTCGGTAAAGCAAAATGATGTTGATATGTTGAATGTATTTGATTTTGAAAAGGCTGGGAATTC
AGAACCAAATGAATTAAAAAATGAAAGTGAAGTAACAATTCAGCAGGAACGTCAACAATACCAAAAGGCTTTGGATATGTTATTGTCGGC
ACCAAAGGATGAGAACGAGATATTCCCTTCACCAACTGAATTTTTCATGCCTATTTATAAATCAAAGCATTCAGAAGGGGTTATAATTCA
ACAGGTGAATGATGAAACAAATCTTGAAACTTCAACTTTGGATGAAAATCATCCAAGTATTTCAGACAGTTTAACAGATCGGGAAACTTC
TGTGAATGTCATTGAAGGTGATAGTGACCCTGAAAAGGTTGAGATTTCAAATGGATTATGTGGTCTTAACACATCACCCTCCCAATCTGT
TCAGTTCTCCAGTGTCAAAGGCGACAATAATCATGACATGGAGTTATCAACTCTTAAAATCATGGAAATGAGCATTGAGGACTGCCCTTT
GGATGTTTAATCTTCATTAATAAATACCTCAAATGGCCAGTAAC

>26438_26438_2_EML1-SPATA7_EML1_chr14_100317372_ENST00000262233_SPATA7_chr14_88857725_ENST00000393545_length(amino acids)=676AA_BP=82
MEDGFSSYSSLYDTSSLLQFCNDDSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALADVVRRLNITEEQQAVLNRKGPTKVRATSVL
PRYGPPCLFKGHLSTKSNAFCTDSSSLRLSTLQLVKNHMAVHYNKILSAKAAVDCSVPVSVSTSIKYADQQRREKLKKELAQCEKEFKLT
KTAMRANYKNNSKSLFNTLQKPSGEPQIEDDMLKEEMNGFSSFARSLVPSSERLHLSLHKSSKVITNGPEKNSSSSPSSVDYAASGPRKL
SSGALYGRRPRSTFPNSHRFQLVISKAPSGDLLDKHSELFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRKKDFTDQRIEAETQTELSF
KSELGTAETKNMTDSEMNIKQASNCVTYDAKEKIAPLPLEGHDSTWDEIKDDALQHSSPRAMCQYSLKPPSTRKIYSDEEELLYLSFIED
VTDEILKLGLFSNRFLERLFERHIKQNKHLEEEKMRHLLHVLKVDLGCTSEENSVKQNDVDMLNVFDFEKAGNSEPNELKNESEVTIQQE
RQQYQKALDMLLSAPKDENEIFPSPTEFFMPIYKSKHSEGVIIQQVNDETNLETSTLDENHPSISDSLTDRETSVNVIEGDSDPEKVEIS
NGLCGLNTSPSQSVQFSSVKGDNNHDMELSTLKIMEMSIEDCPLDV

--------------------------------------------------------------
>26438_26438_3_EML1-SPATA7_EML1_chr14_100317372_ENST00000262233_SPATA7_chr14_88857725_ENST00000556553_length(transcript)=2112nt_BP=389nt
ATGGTAACCGGCAGCAGCAGCCGCCACAGCAGGGCCGGCCCCAGCGCCAGCGCCGGTCGCGGTCGGGCTCAGCTCAGTGTGTGGTGAGCG
GCGGCGGCGCGGCCGGGCCGGGGAGCGGGCGCGGCCCGGCGGCCTCAGCATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACAC
GTCCTCGCTGCTCCAGTTCTGCAACGATGACAGCGCTTCTGCTGCAAGTAGCATGGAGGTGACAGACCGCATTGCTTCACTGGAGCAGAG
AGTCCAGATGCAAGAAGACGACATCCAGCTGCTCAAATCAGCTCTAGCTGATGTGGTTCGGCGGCTGAACATTACTGAGGAACAGCAGGC
CGTGCTTAACAGGAAAGGACCTACCAAAGTCAGAGCAACCTCTGTCCTTCCCAGATATGGTCCACCGTGCCTATTTAAAGGACACTTGAG
CACCAAAAGTAATGCTGCAGTAGACTGCTCGGTTCCAGTAAGCGTGAGTACCAGCATAAAGTATGCAGACCAACAACGAAGAGAGAAACT
CAAAAAGGAATTAGCACAATGTGAAAAAGAGTTCAAATTAACTAAAACTGCAATGCGAGCCAATTATAAAAATAATTCCAAGTCACTTTT
TAATACCTTACAAAAGCCCTCAGGCGAACCGCAAATTGAGGATGACATGTTAAAAGAAGAAATGAATGGATTTTCATCCTTTGCAAGGTC
ACTAGTACCCTCTTCAGAGAGACTACACCTAAGTCTACATAAATCCAGTAAAGTCATCACAAATGGTCCTGAGAAGAACTCCAGTTCCTC
CCCGTCCAGTGTGGATTATGCAGCCTCCGGGCCCCGGAAACTGAGCTCTGGAGCCCTGTATGGCAGAAGGCCCAGAAGCACATTCCCAAA
TTCCCACCGGTTTCAGTTAGTCATTTCGAAAGCACCCAGTGGGGATCTTTTGGATAAACATTCTGAACTCTTTTCTAACAAACAATTGCC
ATTCACTCCTCGCACTTTAAAAACAGAAGCAAAATCTTTCCTGTCACAGTATCGCTATTATACACCTGCCAAAAGAAAAAAGGATTTTAC
AGATCAACGGATAGAAGCTGAAACCCAGACTGAATTAAGCTTTAAATCTGAGTTGGGGACAGCTGAGACTAAAAACATGACAGATTCAGA
AATGAACATAAAGCAGGCATCTAATTGTGTGACATATGATGCCAAAGAAAAAATAGCTCCTTTACCTTTAGAAGGGCATGACTCAACATG
GGATGAGATTAAGGATGATGCTCTTCAGCATTCCTCACCAAGGGCAATGTGTCAGTATTCCCTGAAGCCCCCTTCAACTCGTAAAATCTA
CTCTGATGAAGAAGAACTGTTGTATCTGAGTTTCATTGAAGATGTAACAGATGAAATTTTGAAACTTGGTTTATTTTCAAACAGGTTTTT
AGAACGACTGTTCGAGCGACATATAAAACAAAATAAACATTTGGAGGAGGAAAAAATGCGCCACCTGCTGCATGTCCTGAAAGTAGACTT
AGGCTGCACATCGGAGGAAAACTCGGTAAAGCAAAATGATGTTGATATGTTGAATGTATTTGATTTTGAAAAGGCTGGGAATTCAGAACC
AAATGAATTAAAAAATGAAAGTGAAGTAACAATTCAGCAGGAACGTCAACAATACCAAAAGGCTTTGGATATGTTATTGTCGGCACCAAA
GGATGAGAACGAGATATTCCCTTCACCAACTGAATTTTTCATGCCTATTTATAAATCAAAGCATTCAGAAGGGGTTATAATTCAACAGGT
GAATGATGAAACAAATCTTGAAACTTCAACTTTGGATGAAAATCATCCAAGTATTTCAGACAGTTTAACAGATCGGGAAACTTCTGTGAA
TGTCATTGAAGGTGATAGTGACCCTGAAAAGGTTGAGATTTCAAATGGATTATGTGGTCTTAACACATCACCCTCCCAATCTGTTCAGTT
CTCCAGTGTCAAAGGCGACAATAATCATGACATGGAGTTATCAACTCTTAAAATCATGGAAATGAGCATTGAGGACTGCCCTTTGGATGT
TTAATCTTCATTAATAAATACCTCAAATGGCCAGTAACTCAA

>26438_26438_3_EML1-SPATA7_EML1_chr14_100317372_ENST00000262233_SPATA7_chr14_88857725_ENST00000556553_length(amino acids)=644AA_BP=82
MEDGFSSYSSLYDTSSLLQFCNDDSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALADVVRRLNITEEQQAVLNRKGPTKVRATSVL
PRYGPPCLFKGHLSTKSNAAVDCSVPVSVSTSIKYADQQRREKLKKELAQCEKEFKLTKTAMRANYKNNSKSLFNTLQKPSGEPQIEDDM
LKEEMNGFSSFARSLVPSSERLHLSLHKSSKVITNGPEKNSSSSPSSVDYAASGPRKLSSGALYGRRPRSTFPNSHRFQLVISKAPSGDL
LDKHSELFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRKKDFTDQRIEAETQTELSFKSELGTAETKNMTDSEMNIKQASNCVTYDAKE
KIAPLPLEGHDSTWDEIKDDALQHSSPRAMCQYSLKPPSTRKIYSDEEELLYLSFIEDVTDEILKLGLFSNRFLERLFERHIKQNKHLEE
EKMRHLLHVLKVDLGCTSEENSVKQNDVDMLNVFDFEKAGNSEPNELKNESEVTIQQERQQYQKALDMLLSAPKDENEIFPSPTEFFMPI
YKSKHSEGVIIQQVNDETNLETSTLDENHPSISDSLTDRETSVNVIEGDSDPEKVEISNGLCGLNTSPSQSVQFSSVKGDNNHDMELSTL
KIMEMSIEDCPLDV

--------------------------------------------------------------
>26438_26438_4_EML1-SPATA7_EML1_chr14_100317372_ENST00000327921_SPATA7_chr14_88857725_ENST00000356583_length(transcript)=2969nt_BP=1248nt
TCCATGGCTTAGAAGGCTTTGCATCTTGAACATCCTGGATGCAGAGCGGTCACAGGCCATCCCCACAGATAGGTTCCTACAGATGGGGTG
TGTGACCATGTTCTCTCCTCCTCCACACCCCTCTGGGGCTTACAGCTACCAAAGCCCAAAATCCTTCAGGGCTCAGGCCTCAGGGCTAAA
CAGTGATTCACAGACTTTCACACTTCCCCACACACCCCCGCGCATGCCAACTTTTTGTTTCGGTAAATAAAGACATTCAAAAGTAATGAC
CATCTACTCTGGCCCTCATTTCATAAAAGCAAGGCTACTTTATCACCAATGTCAGATGAACAATCTCAGAATAAGGCTAAGTTCTAAAAT
TAAAATACATTTTATTTCATGACAAACTCCCTCTACATTTTCCTCACTATTCTGTAGACAGGCACTGGGGAGCCTCCCACACAGCTAGGG
CCCCTGGAGCACAGGCTGCAAAGACCCCAGGAGGTCCCAGAATCTACCTGCCTTAGGCCCAGAGAGGGGTGGACGTTGCCCAGGACCATG
CCGCTGGAACAGGAAAAAGGTTTTCCAGTTTTACCCCAGGCAATTCTCCATCAAAATGCCATCTGACTACAAAGAGGCAGGCACTTGCTT
CCGGATCCCCTCTCTGCTCTGCAGAACTCCCAGGCCACGGAGCTGATTTCACTAACTGCAGCCGTCCCCCTGGGGCGCCCCGTCTGCCCT
ACTTGCCATCACCCAGATGCGCAGGATCTTGTGGCAGAAAGCAGGAGCCTGGATGGGAAGAGGAGCAGCCAGGCCGAGGTGGGCGCCGCT
CCCCCTCCCCGGCCCTGCCCAGGTCCTCAGAGAGCTGGGACCTGAGACTCATTAGTGCCTGCATAATGGATGCCTCCTTCTCTCTTCTTG
GAAATCCCCAGCCCATCTTGCTTAATGGCCACGAGGGAAGTGGGATACCGGCGCTCTGCTCGTAAAGCCGGCCTCTGCCCCCCGCATCTC
CCCTTGGAGGAGGGGCGGCTGGGCGGCTTACACAGGGGAGGCCTGGTCTCTTGTCTTCTGCTTCACGACGGCTGGATGACAGCGCTTCTG
CTGCAAGTAGCATGGAGGTGACAGACCGCATTGCTTCACTGGAGCAGAGAGTCCAGATGCAAGAAGACGACATCCAGCTGCTCAAATCAG
CTCTAGCTGATGTGGTTCGGCGGCTGAACATTACTGAGGAACAGCAGGCCGTGCTTAACAGGAAAGGACCTACCAAAGTCAGAGCAACCT
CTGTCCTTCCCAGATATGGTCCACCGTGCCTATTTAAAGGACACTTGAGCACCAAAAGTAATGCTGCAGTAGACTGCTCGGTTCCAGTAA
GCGTGAGTACCAGCATAAAGTATGCAGACCAACAACGAAGAGAGAAACTCAAAAAGGAATTAGCACAATGTGAAAAAGAGTTCAAATTAA
CTAAAACTGCAATGCGAGCCAATTATAAAAATAATTCCAAGTCACTTTTTAATACCTTACAAAAGCCCTCAGGCGAACCGCAAATTGAGG
ATGACATGTTAAAAGAAGAAATGAATGGATTTTCATCCTTTGCAAGGTCACTAGTACCCTCTTCAGAGAGACTACACCTAAGTCTACATA
AATCCAGTAAAGTCATCACAAATGGTCCTGAGAAGAACTCCAGTTCCTCCCCGTCCAGTGTGGATTATGCAGCCTCCGGGCCCCGGAAAC
TGAGCTCTGGAGCCCTGTATGGCAGAAGGCCCAGAAGCACATTCCCAAATTCCCACCGGTTTCAGTTAGTCATTTCGAAAGCACCCAGTG
GGGATCTTTTGGATAAACATTCTGAACTCTTTTCTAACAAACAATTGCCATTCACTCCTCGCACTTTAAAAACAGAAGCAAAATCTTTCC
TGTCACAGTATCGCTATTATACACCTGCCAAAAGAAAAAAGGATTTTACAGATCAACGGATAGAAGCTGAAACCCAGACTGAATTAAGCT
TTAAATCTGAGTTGGGGACAGCTGAGACTAAAAACATGACAGATTCAGAAATGAACATAAAGCAGGCATCTAATTGTGTGACATATGATG
CCAAAGAAAAAATAGCTCCTTTACCTTTAGAAGGGCATGACTCAACATGGGATGAGATTAAGGATGATGCTCTTCAGCATTCCTCACCAA
GGGCAATGTGTCAGTATTCCCTGAAGCCCCCTTCAACTCGTAAAATCTACTCTGATGAAGAAGAACTGTTGTATCTGAGTTTCATTGAAG
ATGTAACAGATGAAATTTTGAAACTTGGTTTATTTTCAAACAGGTTTTTAGAACGACTGTTCGAGCGACATATAAAACAAAATAAACATT
TGGAGGAGGAAAAAATGCGCCACCTGCTGCATGTCCTGAAAGTAGACTTAGGCTGCACATCGGAGGAAAACTCGGTAAAGCAAAATGATG
TTGATATGTTGAATGTATTTGATTTTGAAAAGGCTGGGAATTCAGAACCAAATGAATTAAAAAATGAAAGTGAAGTAACAATTCAGCAGG
AACGTCAACAATACCAAAAGGCTTTGGATATGTTATTGTCGGCACCAAAGGATGAGAACGAGATATTCCCTTCACCAACTGAATTTTTCA
TGCCTATTTATAAATCAAAGCATTCAGAAGGGGTTATAATTCAACAGGTGAATGATGAAACAAATCTTGAAACTTCAACTTTGGATGAAA
ATCATCCAAGTATTTCAGACAGTTTAACAGATCGGGAAACTTCTGTGAATGTCATTGAAGGTGATAGTGACCCTGAAAAGGTTGAGATTT
CAAATGGATTATGTGGTCTTAACACATCACCCTCCCAATCTGTTCAGTTCTCCAGTGTCAAAGGCGACAATAATCATGACATGGAGTTAT
CAACTCTTAAAATCATGGAAATGAGCATTGAGGACTGCCCTTTGGATGTTTAATCTTCATTAATAAATACCTCAAATGGCCAGTAACTC

>26438_26438_4_EML1-SPATA7_EML1_chr14_100317372_ENST00000327921_SPATA7_chr14_88857725_ENST00000356583_length(amino acids)=652AA_BP=90
MPPASPLGGGAAGRLTQGRPGLLSSASRRLDDSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALADVVRRLNITEEQQAVLNRKGPT
KVRATSVLPRYGPPCLFKGHLSTKSNAAVDCSVPVSVSTSIKYADQQRREKLKKELAQCEKEFKLTKTAMRANYKNNSKSLFNTLQKPSG
EPQIEDDMLKEEMNGFSSFARSLVPSSERLHLSLHKSSKVITNGPEKNSSSSPSSVDYAASGPRKLSSGALYGRRPRSTFPNSHRFQLVI
SKAPSGDLLDKHSELFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRKKDFTDQRIEAETQTELSFKSELGTAETKNMTDSEMNIKQASN
CVTYDAKEKIAPLPLEGHDSTWDEIKDDALQHSSPRAMCQYSLKPPSTRKIYSDEEELLYLSFIEDVTDEILKLGLFSNRFLERLFERHI
KQNKHLEEEKMRHLLHVLKVDLGCTSEENSVKQNDVDMLNVFDFEKAGNSEPNELKNESEVTIQQERQQYQKALDMLLSAPKDENEIFPS
PTEFFMPIYKSKHSEGVIIQQVNDETNLETSTLDENHPSISDSLTDRETSVNVIEGDSDPEKVEISNGLCGLNTSPSQSVQFSSVKGDNN
HDMELSTLKIMEMSIEDCPLDV

--------------------------------------------------------------
>26438_26438_5_EML1-SPATA7_EML1_chr14_100317372_ENST00000327921_SPATA7_chr14_88857725_ENST00000393545_length(transcript)=3063nt_BP=1248nt
TCCATGGCTTAGAAGGCTTTGCATCTTGAACATCCTGGATGCAGAGCGGTCACAGGCCATCCCCACAGATAGGTTCCTACAGATGGGGTG
TGTGACCATGTTCTCTCCTCCTCCACACCCCTCTGGGGCTTACAGCTACCAAAGCCCAAAATCCTTCAGGGCTCAGGCCTCAGGGCTAAA
CAGTGATTCACAGACTTTCACACTTCCCCACACACCCCCGCGCATGCCAACTTTTTGTTTCGGTAAATAAAGACATTCAAAAGTAATGAC
CATCTACTCTGGCCCTCATTTCATAAAAGCAAGGCTACTTTATCACCAATGTCAGATGAACAATCTCAGAATAAGGCTAAGTTCTAAAAT
TAAAATACATTTTATTTCATGACAAACTCCCTCTACATTTTCCTCACTATTCTGTAGACAGGCACTGGGGAGCCTCCCACACAGCTAGGG
CCCCTGGAGCACAGGCTGCAAAGACCCCAGGAGGTCCCAGAATCTACCTGCCTTAGGCCCAGAGAGGGGTGGACGTTGCCCAGGACCATG
CCGCTGGAACAGGAAAAAGGTTTTCCAGTTTTACCCCAGGCAATTCTCCATCAAAATGCCATCTGACTACAAAGAGGCAGGCACTTGCTT
CCGGATCCCCTCTCTGCTCTGCAGAACTCCCAGGCCACGGAGCTGATTTCACTAACTGCAGCCGTCCCCCTGGGGCGCCCCGTCTGCCCT
ACTTGCCATCACCCAGATGCGCAGGATCTTGTGGCAGAAAGCAGGAGCCTGGATGGGAAGAGGAGCAGCCAGGCCGAGGTGGGCGCCGCT
CCCCCTCCCCGGCCCTGCCCAGGTCCTCAGAGAGCTGGGACCTGAGACTCATTAGTGCCTGCATAATGGATGCCTCCTTCTCTCTTCTTG
GAAATCCCCAGCCCATCTTGCTTAATGGCCACGAGGGAAGTGGGATACCGGCGCTCTGCTCGTAAAGCCGGCCTCTGCCCCCCGCATCTC
CCCTTGGAGGAGGGGCGGCTGGGCGGCTTACACAGGGGAGGCCTGGTCTCTTGTCTTCTGCTTCACGACGGCTGGATGACAGCGCTTCTG
CTGCAAGTAGCATGGAGGTGACAGACCGCATTGCTTCACTGGAGCAGAGAGTCCAGATGCAAGAAGACGACATCCAGCTGCTCAAATCAG
CTCTAGCTGATGTGGTTCGGCGGCTGAACATTACTGAGGAACAGCAGGCCGTGCTTAACAGGAAAGGACCTACCAAAGTCAGAGCAACCT
CTGTCCTTCCCAGATATGGTCCACCGTGCCTATTTAAAGGACACTTGAGCACCAAAAGTAATGCTTTTTGCACTGACTCCTCTTCTCTCA
GACTAAGCACTCTCCAGCTGGTCAAGAATCACATGGCTGTTCACTATAATAAAATCCTTTCAGCCAAAGCTGCAGTAGACTGCTCGGTTC
CAGTAAGCGTGAGTACCAGCATAAAGTATGCAGACCAACAACGAAGAGAGAAACTCAAAAAGGAATTAGCACAATGTGAAAAAGAGTTCA
AATTAACTAAAACTGCAATGCGAGCCAATTATAAAAATAATTCCAAGTCACTTTTTAATACCTTACAAAAGCCCTCAGGCGAACCGCAAA
TTGAGGATGACATGTTAAAAGAAGAAATGAATGGATTTTCATCCTTTGCAAGGTCACTAGTACCCTCTTCAGAGAGACTACACCTAAGTC
TACATAAATCCAGTAAAGTCATCACAAATGGTCCTGAGAAGAACTCCAGTTCCTCCCCGTCCAGTGTGGATTATGCAGCCTCCGGGCCCC
GGAAACTGAGCTCTGGAGCCCTGTATGGCAGAAGGCCCAGAAGCACATTCCCAAATTCCCACCGGTTTCAGTTAGTCATTTCGAAAGCAC
CCAGTGGGGATCTTTTGGATAAACATTCTGAACTCTTTTCTAACAAACAATTGCCATTCACTCCTCGCACTTTAAAAACAGAAGCAAAAT
CTTTCCTGTCACAGTATCGCTATTATACACCTGCCAAAAGAAAAAAGGATTTTACAGATCAACGGATAGAAGCTGAAACCCAGACTGAAT
TAAGCTTTAAATCTGAGTTGGGGACAGCTGAGACTAAAAACATGACAGATTCAGAAATGAACATAAAGCAGGCATCTAATTGTGTGACAT
ATGATGCCAAAGAAAAAATAGCTCCTTTACCTTTAGAAGGGCATGACTCAACATGGGATGAGATTAAGGATGATGCTCTTCAGCATTCCT
CACCAAGGGCAATGTGTCAGTATTCCCTGAAGCCCCCTTCAACTCGTAAAATCTACTCTGATGAAGAAGAACTGTTGTATCTGAGTTTCA
TTGAAGATGTAACAGATGAAATTTTGAAACTTGGTTTATTTTCAAACAGGTTTTTAGAACGACTGTTCGAGCGACATATAAAACAAAATA
AACATTTGGAGGAGGAAAAAATGCGCCACCTGCTGCATGTCCTGAAAGTAGACTTAGGCTGCACATCGGAGGAAAACTCGGTAAAGCAAA
ATGATGTTGATATGTTGAATGTATTTGATTTTGAAAAGGCTGGGAATTCAGAACCAAATGAATTAAAAAATGAAAGTGAAGTAACAATTC
AGCAGGAACGTCAACAATACCAAAAGGCTTTGGATATGTTATTGTCGGCACCAAAGGATGAGAACGAGATATTCCCTTCACCAACTGAAT
TTTTCATGCCTATTTATAAATCAAAGCATTCAGAAGGGGTTATAATTCAACAGGTGAATGATGAAACAAATCTTGAAACTTCAACTTTGG
ATGAAAATCATCCAAGTATTTCAGACAGTTTAACAGATCGGGAAACTTCTGTGAATGTCATTGAAGGTGATAGTGACCCTGAAAAGGTTG
AGATTTCAAATGGATTATGTGGTCTTAACACATCACCCTCCCAATCTGTTCAGTTCTCCAGTGTCAAAGGCGACAATAATCATGACATGG
AGTTATCAACTCTTAAAATCATGGAAATGAGCATTGAGGACTGCCCTTTGGATGTTTAATCTTCATTAATAAATACCTCAAATGGCCAGT
AAC

>26438_26438_5_EML1-SPATA7_EML1_chr14_100317372_ENST00000327921_SPATA7_chr14_88857725_ENST00000393545_length(amino acids)=684AA_BP=90
MPPASPLGGGAAGRLTQGRPGLLSSASRRLDDSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALADVVRRLNITEEQQAVLNRKGPT
KVRATSVLPRYGPPCLFKGHLSTKSNAFCTDSSSLRLSTLQLVKNHMAVHYNKILSAKAAVDCSVPVSVSTSIKYADQQRREKLKKELAQ
CEKEFKLTKTAMRANYKNNSKSLFNTLQKPSGEPQIEDDMLKEEMNGFSSFARSLVPSSERLHLSLHKSSKVITNGPEKNSSSSPSSVDY
AASGPRKLSSGALYGRRPRSTFPNSHRFQLVISKAPSGDLLDKHSELFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRKKDFTDQRIEA
ETQTELSFKSELGTAETKNMTDSEMNIKQASNCVTYDAKEKIAPLPLEGHDSTWDEIKDDALQHSSPRAMCQYSLKPPSTRKIYSDEEEL
LYLSFIEDVTDEILKLGLFSNRFLERLFERHIKQNKHLEEEKMRHLLHVLKVDLGCTSEENSVKQNDVDMLNVFDFEKAGNSEPNELKNE
SEVTIQQERQQYQKALDMLLSAPKDENEIFPSPTEFFMPIYKSKHSEGVIIQQVNDETNLETSTLDENHPSISDSLTDRETSVNVIEGDS
DPEKVEISNGLCGLNTSPSQSVQFSSVKGDNNHDMELSTLKIMEMSIEDCPLDV

--------------------------------------------------------------
>26438_26438_6_EML1-SPATA7_EML1_chr14_100317372_ENST00000327921_SPATA7_chr14_88857725_ENST00000556553_length(transcript)=2971nt_BP=1248nt
TCCATGGCTTAGAAGGCTTTGCATCTTGAACATCCTGGATGCAGAGCGGTCACAGGCCATCCCCACAGATAGGTTCCTACAGATGGGGTG
TGTGACCATGTTCTCTCCTCCTCCACACCCCTCTGGGGCTTACAGCTACCAAAGCCCAAAATCCTTCAGGGCTCAGGCCTCAGGGCTAAA
CAGTGATTCACAGACTTTCACACTTCCCCACACACCCCCGCGCATGCCAACTTTTTGTTTCGGTAAATAAAGACATTCAAAAGTAATGAC
CATCTACTCTGGCCCTCATTTCATAAAAGCAAGGCTACTTTATCACCAATGTCAGATGAACAATCTCAGAATAAGGCTAAGTTCTAAAAT
TAAAATACATTTTATTTCATGACAAACTCCCTCTACATTTTCCTCACTATTCTGTAGACAGGCACTGGGGAGCCTCCCACACAGCTAGGG
CCCCTGGAGCACAGGCTGCAAAGACCCCAGGAGGTCCCAGAATCTACCTGCCTTAGGCCCAGAGAGGGGTGGACGTTGCCCAGGACCATG
CCGCTGGAACAGGAAAAAGGTTTTCCAGTTTTACCCCAGGCAATTCTCCATCAAAATGCCATCTGACTACAAAGAGGCAGGCACTTGCTT
CCGGATCCCCTCTCTGCTCTGCAGAACTCCCAGGCCACGGAGCTGATTTCACTAACTGCAGCCGTCCCCCTGGGGCGCCCCGTCTGCCCT
ACTTGCCATCACCCAGATGCGCAGGATCTTGTGGCAGAAAGCAGGAGCCTGGATGGGAAGAGGAGCAGCCAGGCCGAGGTGGGCGCCGCT
CCCCCTCCCCGGCCCTGCCCAGGTCCTCAGAGAGCTGGGACCTGAGACTCATTAGTGCCTGCATAATGGATGCCTCCTTCTCTCTTCTTG
GAAATCCCCAGCCCATCTTGCTTAATGGCCACGAGGGAAGTGGGATACCGGCGCTCTGCTCGTAAAGCCGGCCTCTGCCCCCCGCATCTC
CCCTTGGAGGAGGGGCGGCTGGGCGGCTTACACAGGGGAGGCCTGGTCTCTTGTCTTCTGCTTCACGACGGCTGGATGACAGCGCTTCTG
CTGCAAGTAGCATGGAGGTGACAGACCGCATTGCTTCACTGGAGCAGAGAGTCCAGATGCAAGAAGACGACATCCAGCTGCTCAAATCAG
CTCTAGCTGATGTGGTTCGGCGGCTGAACATTACTGAGGAACAGCAGGCCGTGCTTAACAGGAAAGGACCTACCAAAGTCAGAGCAACCT
CTGTCCTTCCCAGATATGGTCCACCGTGCCTATTTAAAGGACACTTGAGCACCAAAAGTAATGCTGCAGTAGACTGCTCGGTTCCAGTAA
GCGTGAGTACCAGCATAAAGTATGCAGACCAACAACGAAGAGAGAAACTCAAAAAGGAATTAGCACAATGTGAAAAAGAGTTCAAATTAA
CTAAAACTGCAATGCGAGCCAATTATAAAAATAATTCCAAGTCACTTTTTAATACCTTACAAAAGCCCTCAGGCGAACCGCAAATTGAGG
ATGACATGTTAAAAGAAGAAATGAATGGATTTTCATCCTTTGCAAGGTCACTAGTACCCTCTTCAGAGAGACTACACCTAAGTCTACATA
AATCCAGTAAAGTCATCACAAATGGTCCTGAGAAGAACTCCAGTTCCTCCCCGTCCAGTGTGGATTATGCAGCCTCCGGGCCCCGGAAAC
TGAGCTCTGGAGCCCTGTATGGCAGAAGGCCCAGAAGCACATTCCCAAATTCCCACCGGTTTCAGTTAGTCATTTCGAAAGCACCCAGTG
GGGATCTTTTGGATAAACATTCTGAACTCTTTTCTAACAAACAATTGCCATTCACTCCTCGCACTTTAAAAACAGAAGCAAAATCTTTCC
TGTCACAGTATCGCTATTATACACCTGCCAAAAGAAAAAAGGATTTTACAGATCAACGGATAGAAGCTGAAACCCAGACTGAATTAAGCT
TTAAATCTGAGTTGGGGACAGCTGAGACTAAAAACATGACAGATTCAGAAATGAACATAAAGCAGGCATCTAATTGTGTGACATATGATG
CCAAAGAAAAAATAGCTCCTTTACCTTTAGAAGGGCATGACTCAACATGGGATGAGATTAAGGATGATGCTCTTCAGCATTCCTCACCAA
GGGCAATGTGTCAGTATTCCCTGAAGCCCCCTTCAACTCGTAAAATCTACTCTGATGAAGAAGAACTGTTGTATCTGAGTTTCATTGAAG
ATGTAACAGATGAAATTTTGAAACTTGGTTTATTTTCAAACAGGTTTTTAGAACGACTGTTCGAGCGACATATAAAACAAAATAAACATT
TGGAGGAGGAAAAAATGCGCCACCTGCTGCATGTCCTGAAAGTAGACTTAGGCTGCACATCGGAGGAAAACTCGGTAAAGCAAAATGATG
TTGATATGTTGAATGTATTTGATTTTGAAAAGGCTGGGAATTCAGAACCAAATGAATTAAAAAATGAAAGTGAAGTAACAATTCAGCAGG
AACGTCAACAATACCAAAAGGCTTTGGATATGTTATTGTCGGCACCAAAGGATGAGAACGAGATATTCCCTTCACCAACTGAATTTTTCA
TGCCTATTTATAAATCAAAGCATTCAGAAGGGGTTATAATTCAACAGGTGAATGATGAAACAAATCTTGAAACTTCAACTTTGGATGAAA
ATCATCCAAGTATTTCAGACAGTTTAACAGATCGGGAAACTTCTGTGAATGTCATTGAAGGTGATAGTGACCCTGAAAAGGTTGAGATTT
CAAATGGATTATGTGGTCTTAACACATCACCCTCCCAATCTGTTCAGTTCTCCAGTGTCAAAGGCGACAATAATCATGACATGGAGTTAT
CAACTCTTAAAATCATGGAAATGAGCATTGAGGACTGCCCTTTGGATGTTTAATCTTCATTAATAAATACCTCAAATGGCCAGTAACTCA
A

>26438_26438_6_EML1-SPATA7_EML1_chr14_100317372_ENST00000327921_SPATA7_chr14_88857725_ENST00000556553_length(amino acids)=652AA_BP=90
MPPASPLGGGAAGRLTQGRPGLLSSASRRLDDSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALADVVRRLNITEEQQAVLNRKGPT
KVRATSVLPRYGPPCLFKGHLSTKSNAAVDCSVPVSVSTSIKYADQQRREKLKKELAQCEKEFKLTKTAMRANYKNNSKSLFNTLQKPSG
EPQIEDDMLKEEMNGFSSFARSLVPSSERLHLSLHKSSKVITNGPEKNSSSSPSSVDYAASGPRKLSSGALYGRRPRSTFPNSHRFQLVI
SKAPSGDLLDKHSELFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRKKDFTDQRIEAETQTELSFKSELGTAETKNMTDSEMNIKQASN
CVTYDAKEKIAPLPLEGHDSTWDEIKDDALQHSSPRAMCQYSLKPPSTRKIYSDEEELLYLSFIEDVTDEILKLGLFSNRFLERLFERHI
KQNKHLEEEKMRHLLHVLKVDLGCTSEENSVKQNDVDMLNVFDFEKAGNSEPNELKNESEVTIQQERQQYQKALDMLLSAPKDENEIFPS
PTEFFMPIYKSKHSEGVIIQQVNDETNLETSTLDENHPSISDSLTDRETSVNVIEGDSDPEKVEISNGLCGLNTSPSQSVQFSSVKGDNN
HDMELSTLKIMEMSIEDCPLDV

--------------------------------------------------------------
>26438_26438_7_EML1-SPATA7_EML1_chr14_100317372_ENST00000334192_SPATA7_chr14_88857725_ENST00000356583_length(transcript)=2105nt_BP=384nt
AACCGGCAGCAGCAGCCGCCACAGCAGGGCCGGCCCCAGCGCCAGCGCCGGTCGCGGTCGGGCTCAGCTCAGTGTGTGGTGAGCGGCGGC
GGCGCGGCCGGGCCGGGGAGCGGGCGCGGCCCGGCGGCCTCAGCATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACACGTCCT
CGCTGCTCCAGTTCTGCAACGATGACAGCGCTTCTGCTGCAAGTAGCATGGAGGTGACAGACCGCATTGCTTCACTGGAGCAGAGAGTCC
AGATGCAAGAAGACGACATCCAGCTGCTCAAATCAGCTCTAGCTGATGTGGTTCGGCGGCTGAACATTACTGAGGAACAGCAGGCCGTGC
TTAACAGGAAAGGACCTACCAAAGTCAGAGCAACCTCTGTCCTTCCCAGATATGGTCCACCGTGCCTATTTAAAGGACACTTGAGCACCA
AAAGTAATGCTGCAGTAGACTGCTCGGTTCCAGTAAGCGTGAGTACCAGCATAAAGTATGCAGACCAACAACGAAGAGAGAAACTCAAAA
AGGAATTAGCACAATGTGAAAAAGAGTTCAAATTAACTAAAACTGCAATGCGAGCCAATTATAAAAATAATTCCAAGTCACTTTTTAATA
CCTTACAAAAGCCCTCAGGCGAACCGCAAATTGAGGATGACATGTTAAAAGAAGAAATGAATGGATTTTCATCCTTTGCAAGGTCACTAG
TACCCTCTTCAGAGAGACTACACCTAAGTCTACATAAATCCAGTAAAGTCATCACAAATGGTCCTGAGAAGAACTCCAGTTCCTCCCCGT
CCAGTGTGGATTATGCAGCCTCCGGGCCCCGGAAACTGAGCTCTGGAGCCCTGTATGGCAGAAGGCCCAGAAGCACATTCCCAAATTCCC
ACCGGTTTCAGTTAGTCATTTCGAAAGCACCCAGTGGGGATCTTTTGGATAAACATTCTGAACTCTTTTCTAACAAACAATTGCCATTCA
CTCCTCGCACTTTAAAAACAGAAGCAAAATCTTTCCTGTCACAGTATCGCTATTATACACCTGCCAAAAGAAAAAAGGATTTTACAGATC
AACGGATAGAAGCTGAAACCCAGACTGAATTAAGCTTTAAATCTGAGTTGGGGACAGCTGAGACTAAAAACATGACAGATTCAGAAATGA
ACATAAAGCAGGCATCTAATTGTGTGACATATGATGCCAAAGAAAAAATAGCTCCTTTACCTTTAGAAGGGCATGACTCAACATGGGATG
AGATTAAGGATGATGCTCTTCAGCATTCCTCACCAAGGGCAATGTGTCAGTATTCCCTGAAGCCCCCTTCAACTCGTAAAATCTACTCTG
ATGAAGAAGAACTGTTGTATCTGAGTTTCATTGAAGATGTAACAGATGAAATTTTGAAACTTGGTTTATTTTCAAACAGGTTTTTAGAAC
GACTGTTCGAGCGACATATAAAACAAAATAAACATTTGGAGGAGGAAAAAATGCGCCACCTGCTGCATGTCCTGAAAGTAGACTTAGGCT
GCACATCGGAGGAAAACTCGGTAAAGCAAAATGATGTTGATATGTTGAATGTATTTGATTTTGAAAAGGCTGGGAATTCAGAACCAAATG
AATTAAAAAATGAAAGTGAAGTAACAATTCAGCAGGAACGTCAACAATACCAAAAGGCTTTGGATATGTTATTGTCGGCACCAAAGGATG
AGAACGAGATATTCCCTTCACCAACTGAATTTTTCATGCCTATTTATAAATCAAAGCATTCAGAAGGGGTTATAATTCAACAGGTGAATG
ATGAAACAAATCTTGAAACTTCAACTTTGGATGAAAATCATCCAAGTATTTCAGACAGTTTAACAGATCGGGAAACTTCTGTGAATGTCA
TTGAAGGTGATAGTGACCCTGAAAAGGTTGAGATTTCAAATGGATTATGTGGTCTTAACACATCACCCTCCCAATCTGTTCAGTTCTCCA
GTGTCAAAGGCGACAATAATCATGACATGGAGTTATCAACTCTTAAAATCATGGAAATGAGCATTGAGGACTGCCCTTTGGATGTTTAAT
CTTCATTAATAAATACCTCAAATGGCCAGTAACTC

>26438_26438_7_EML1-SPATA7_EML1_chr14_100317372_ENST00000334192_SPATA7_chr14_88857725_ENST00000356583_length(amino acids)=644AA_BP=82
MEDGFSSYSSLYDTSSLLQFCNDDSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALADVVRRLNITEEQQAVLNRKGPTKVRATSVL
PRYGPPCLFKGHLSTKSNAAVDCSVPVSVSTSIKYADQQRREKLKKELAQCEKEFKLTKTAMRANYKNNSKSLFNTLQKPSGEPQIEDDM
LKEEMNGFSSFARSLVPSSERLHLSLHKSSKVITNGPEKNSSSSPSSVDYAASGPRKLSSGALYGRRPRSTFPNSHRFQLVISKAPSGDL
LDKHSELFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRKKDFTDQRIEAETQTELSFKSELGTAETKNMTDSEMNIKQASNCVTYDAKE
KIAPLPLEGHDSTWDEIKDDALQHSSPRAMCQYSLKPPSTRKIYSDEEELLYLSFIEDVTDEILKLGLFSNRFLERLFERHIKQNKHLEE
EKMRHLLHVLKVDLGCTSEENSVKQNDVDMLNVFDFEKAGNSEPNELKNESEVTIQQERQQYQKALDMLLSAPKDENEIFPSPTEFFMPI
YKSKHSEGVIIQQVNDETNLETSTLDENHPSISDSLTDRETSVNVIEGDSDPEKVEISNGLCGLNTSPSQSVQFSSVKGDNNHDMELSTL
KIMEMSIEDCPLDV

--------------------------------------------------------------
>26438_26438_8_EML1-SPATA7_EML1_chr14_100317372_ENST00000334192_SPATA7_chr14_88857725_ENST00000393545_length(transcript)=2199nt_BP=384nt
AACCGGCAGCAGCAGCCGCCACAGCAGGGCCGGCCCCAGCGCCAGCGCCGGTCGCGGTCGGGCTCAGCTCAGTGTGTGGTGAGCGGCGGC
GGCGCGGCCGGGCCGGGGAGCGGGCGCGGCCCGGCGGCCTCAGCATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACACGTCCT
CGCTGCTCCAGTTCTGCAACGATGACAGCGCTTCTGCTGCAAGTAGCATGGAGGTGACAGACCGCATTGCTTCACTGGAGCAGAGAGTCC
AGATGCAAGAAGACGACATCCAGCTGCTCAAATCAGCTCTAGCTGATGTGGTTCGGCGGCTGAACATTACTGAGGAACAGCAGGCCGTGC
TTAACAGGAAAGGACCTACCAAAGTCAGAGCAACCTCTGTCCTTCCCAGATATGGTCCACCGTGCCTATTTAAAGGACACTTGAGCACCA
AAAGTAATGCTTTTTGCACTGACTCCTCTTCTCTCAGACTAAGCACTCTCCAGCTGGTCAAGAATCACATGGCTGTTCACTATAATAAAA
TCCTTTCAGCCAAAGCTGCAGTAGACTGCTCGGTTCCAGTAAGCGTGAGTACCAGCATAAAGTATGCAGACCAACAACGAAGAGAGAAAC
TCAAAAAGGAATTAGCACAATGTGAAAAAGAGTTCAAATTAACTAAAACTGCAATGCGAGCCAATTATAAAAATAATTCCAAGTCACTTT
TTAATACCTTACAAAAGCCCTCAGGCGAACCGCAAATTGAGGATGACATGTTAAAAGAAGAAATGAATGGATTTTCATCCTTTGCAAGGT
CACTAGTACCCTCTTCAGAGAGACTACACCTAAGTCTACATAAATCCAGTAAAGTCATCACAAATGGTCCTGAGAAGAACTCCAGTTCCT
CCCCGTCCAGTGTGGATTATGCAGCCTCCGGGCCCCGGAAACTGAGCTCTGGAGCCCTGTATGGCAGAAGGCCCAGAAGCACATTCCCAA
ATTCCCACCGGTTTCAGTTAGTCATTTCGAAAGCACCCAGTGGGGATCTTTTGGATAAACATTCTGAACTCTTTTCTAACAAACAATTGC
CATTCACTCCTCGCACTTTAAAAACAGAAGCAAAATCTTTCCTGTCACAGTATCGCTATTATACACCTGCCAAAAGAAAAAAGGATTTTA
CAGATCAACGGATAGAAGCTGAAACCCAGACTGAATTAAGCTTTAAATCTGAGTTGGGGACAGCTGAGACTAAAAACATGACAGATTCAG
AAATGAACATAAAGCAGGCATCTAATTGTGTGACATATGATGCCAAAGAAAAAATAGCTCCTTTACCTTTAGAAGGGCATGACTCAACAT
GGGATGAGATTAAGGATGATGCTCTTCAGCATTCCTCACCAAGGGCAATGTGTCAGTATTCCCTGAAGCCCCCTTCAACTCGTAAAATCT
ACTCTGATGAAGAAGAACTGTTGTATCTGAGTTTCATTGAAGATGTAACAGATGAAATTTTGAAACTTGGTTTATTTTCAAACAGGTTTT
TAGAACGACTGTTCGAGCGACATATAAAACAAAATAAACATTTGGAGGAGGAAAAAATGCGCCACCTGCTGCATGTCCTGAAAGTAGACT
TAGGCTGCACATCGGAGGAAAACTCGGTAAAGCAAAATGATGTTGATATGTTGAATGTATTTGATTTTGAAAAGGCTGGGAATTCAGAAC
CAAATGAATTAAAAAATGAAAGTGAAGTAACAATTCAGCAGGAACGTCAACAATACCAAAAGGCTTTGGATATGTTATTGTCGGCACCAA
AGGATGAGAACGAGATATTCCCTTCACCAACTGAATTTTTCATGCCTATTTATAAATCAAAGCATTCAGAAGGGGTTATAATTCAACAGG
TGAATGATGAAACAAATCTTGAAACTTCAACTTTGGATGAAAATCATCCAAGTATTTCAGACAGTTTAACAGATCGGGAAACTTCTGTGA
ATGTCATTGAAGGTGATAGTGACCCTGAAAAGGTTGAGATTTCAAATGGATTATGTGGTCTTAACACATCACCCTCCCAATCTGTTCAGT
TCTCCAGTGTCAAAGGCGACAATAATCATGACATGGAGTTATCAACTCTTAAAATCATGGAAATGAGCATTGAGGACTGCCCTTTGGATG
TTTAATCTTCATTAATAAATACCTCAAATGGCCAGTAAC

>26438_26438_8_EML1-SPATA7_EML1_chr14_100317372_ENST00000334192_SPATA7_chr14_88857725_ENST00000393545_length(amino acids)=676AA_BP=82
MEDGFSSYSSLYDTSSLLQFCNDDSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALADVVRRLNITEEQQAVLNRKGPTKVRATSVL
PRYGPPCLFKGHLSTKSNAFCTDSSSLRLSTLQLVKNHMAVHYNKILSAKAAVDCSVPVSVSTSIKYADQQRREKLKKELAQCEKEFKLT
KTAMRANYKNNSKSLFNTLQKPSGEPQIEDDMLKEEMNGFSSFARSLVPSSERLHLSLHKSSKVITNGPEKNSSSSPSSVDYAASGPRKL
SSGALYGRRPRSTFPNSHRFQLVISKAPSGDLLDKHSELFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRKKDFTDQRIEAETQTELSF
KSELGTAETKNMTDSEMNIKQASNCVTYDAKEKIAPLPLEGHDSTWDEIKDDALQHSSPRAMCQYSLKPPSTRKIYSDEEELLYLSFIED
VTDEILKLGLFSNRFLERLFERHIKQNKHLEEEKMRHLLHVLKVDLGCTSEENSVKQNDVDMLNVFDFEKAGNSEPNELKNESEVTIQQE
RQQYQKALDMLLSAPKDENEIFPSPTEFFMPIYKSKHSEGVIIQQVNDETNLETSTLDENHPSISDSLTDRETSVNVIEGDSDPEKVEIS
NGLCGLNTSPSQSVQFSSVKGDNNHDMELSTLKIMEMSIEDCPLDV

--------------------------------------------------------------
>26438_26438_9_EML1-SPATA7_EML1_chr14_100317372_ENST00000334192_SPATA7_chr14_88857725_ENST00000556553_length(transcript)=2107nt_BP=384nt
AACCGGCAGCAGCAGCCGCCACAGCAGGGCCGGCCCCAGCGCCAGCGCCGGTCGCGGTCGGGCTCAGCTCAGTGTGTGGTGAGCGGCGGC
GGCGCGGCCGGGCCGGGGAGCGGGCGCGGCCCGGCGGCCTCAGCATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACACGTCCT
CGCTGCTCCAGTTCTGCAACGATGACAGCGCTTCTGCTGCAAGTAGCATGGAGGTGACAGACCGCATTGCTTCACTGGAGCAGAGAGTCC
AGATGCAAGAAGACGACATCCAGCTGCTCAAATCAGCTCTAGCTGATGTGGTTCGGCGGCTGAACATTACTGAGGAACAGCAGGCCGTGC
TTAACAGGAAAGGACCTACCAAAGTCAGAGCAACCTCTGTCCTTCCCAGATATGGTCCACCGTGCCTATTTAAAGGACACTTGAGCACCA
AAAGTAATGCTGCAGTAGACTGCTCGGTTCCAGTAAGCGTGAGTACCAGCATAAAGTATGCAGACCAACAACGAAGAGAGAAACTCAAAA
AGGAATTAGCACAATGTGAAAAAGAGTTCAAATTAACTAAAACTGCAATGCGAGCCAATTATAAAAATAATTCCAAGTCACTTTTTAATA
CCTTACAAAAGCCCTCAGGCGAACCGCAAATTGAGGATGACATGTTAAAAGAAGAAATGAATGGATTTTCATCCTTTGCAAGGTCACTAG
TACCCTCTTCAGAGAGACTACACCTAAGTCTACATAAATCCAGTAAAGTCATCACAAATGGTCCTGAGAAGAACTCCAGTTCCTCCCCGT
CCAGTGTGGATTATGCAGCCTCCGGGCCCCGGAAACTGAGCTCTGGAGCCCTGTATGGCAGAAGGCCCAGAAGCACATTCCCAAATTCCC
ACCGGTTTCAGTTAGTCATTTCGAAAGCACCCAGTGGGGATCTTTTGGATAAACATTCTGAACTCTTTTCTAACAAACAATTGCCATTCA
CTCCTCGCACTTTAAAAACAGAAGCAAAATCTTTCCTGTCACAGTATCGCTATTATACACCTGCCAAAAGAAAAAAGGATTTTACAGATC
AACGGATAGAAGCTGAAACCCAGACTGAATTAAGCTTTAAATCTGAGTTGGGGACAGCTGAGACTAAAAACATGACAGATTCAGAAATGA
ACATAAAGCAGGCATCTAATTGTGTGACATATGATGCCAAAGAAAAAATAGCTCCTTTACCTTTAGAAGGGCATGACTCAACATGGGATG
AGATTAAGGATGATGCTCTTCAGCATTCCTCACCAAGGGCAATGTGTCAGTATTCCCTGAAGCCCCCTTCAACTCGTAAAATCTACTCTG
ATGAAGAAGAACTGTTGTATCTGAGTTTCATTGAAGATGTAACAGATGAAATTTTGAAACTTGGTTTATTTTCAAACAGGTTTTTAGAAC
GACTGTTCGAGCGACATATAAAACAAAATAAACATTTGGAGGAGGAAAAAATGCGCCACCTGCTGCATGTCCTGAAAGTAGACTTAGGCT
GCACATCGGAGGAAAACTCGGTAAAGCAAAATGATGTTGATATGTTGAATGTATTTGATTTTGAAAAGGCTGGGAATTCAGAACCAAATG
AATTAAAAAATGAAAGTGAAGTAACAATTCAGCAGGAACGTCAACAATACCAAAAGGCTTTGGATATGTTATTGTCGGCACCAAAGGATG
AGAACGAGATATTCCCTTCACCAACTGAATTTTTCATGCCTATTTATAAATCAAAGCATTCAGAAGGGGTTATAATTCAACAGGTGAATG
ATGAAACAAATCTTGAAACTTCAACTTTGGATGAAAATCATCCAAGTATTTCAGACAGTTTAACAGATCGGGAAACTTCTGTGAATGTCA
TTGAAGGTGATAGTGACCCTGAAAAGGTTGAGATTTCAAATGGATTATGTGGTCTTAACACATCACCCTCCCAATCTGTTCAGTTCTCCA
GTGTCAAAGGCGACAATAATCATGACATGGAGTTATCAACTCTTAAAATCATGGAAATGAGCATTGAGGACTGCCCTTTGGATGTTTAAT
CTTCATTAATAAATACCTCAAATGGCCAGTAACTCAA

>26438_26438_9_EML1-SPATA7_EML1_chr14_100317372_ENST00000334192_SPATA7_chr14_88857725_ENST00000556553_length(amino acids)=644AA_BP=82
MEDGFSSYSSLYDTSSLLQFCNDDSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALADVVRRLNITEEQQAVLNRKGPTKVRATSVL
PRYGPPCLFKGHLSTKSNAAVDCSVPVSVSTSIKYADQQRREKLKKELAQCEKEFKLTKTAMRANYKNNSKSLFNTLQKPSGEPQIEDDM
LKEEMNGFSSFARSLVPSSERLHLSLHKSSKVITNGPEKNSSSSPSSVDYAASGPRKLSSGALYGRRPRSTFPNSHRFQLVISKAPSGDL
LDKHSELFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRKKDFTDQRIEAETQTELSFKSELGTAETKNMTDSEMNIKQASNCVTYDAKE
KIAPLPLEGHDSTWDEIKDDALQHSSPRAMCQYSLKPPSTRKIYSDEEELLYLSFIEDVTDEILKLGLFSNRFLERLFERHIKQNKHLEE
EKMRHLLHVLKVDLGCTSEENSVKQNDVDMLNVFDFEKAGNSEPNELKNESEVTIQQERQQYQKALDMLLSAPKDENEIFPSPTEFFMPI
YKSKHSEGVIIQQVNDETNLETSTLDENHPSISDSLTDRETSVNVIEGDSDPEKVEISNGLCGLNTSPSQSVQFSSVKGDNNHDMELSTL
KIMEMSIEDCPLDV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for EML1-SPATA7


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EML1-SPATA7


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for EML1-SPATA7


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneEML1C4284594BAND HETEROTOPIA2GENOMICS_ENGLAND;UNIPROT
HgeneEML1C1848201Subcortical Band Heterotopia1ORPHANET
TgeneC0339527Leber Congenital Amaurosis2CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneC0035334Retinitis Pigmentosa1CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneC1858080Retinal Dystrophy, Early Onset Severe1ORPHANET
TgeneC3540662Congenital Amaurosis of Retinal Origin1CTD_human