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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EMP2-TERF2 (FusionGDB2 ID:HG2013TG7014)

Fusion Gene Summary for EMP2-TERF2

check button Fusion gene summary
Fusion gene informationFusion gene name: EMP2-TERF2
Fusion gene ID: hg2013tg7014
HgeneTgene
Gene symbol

EMP2

TERF2

Gene ID

2013

7014

Gene nameepithelial membrane protein 2telomeric repeat binding factor 2
SynonymsXMPTRBF2|TRF2
Cytomap('EMP2')('TERF2')

16p13.13

16q22.1

Type of geneprotein-codingprotein-coding
Descriptionepithelial membrane protein 2telomeric repeat-binding factor 2TTAGGG repeat-binding factor 2telomeric DNA-binding proteintelomeric repeat binding protein 2
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000359543, ENST00000536829, 
ENST00000566033, 
Fusion gene scores* DoF score15 X 12 X 10=18008 X 7 X 5=280
# samples 1712
** MAII scorelog2(17/1800*10)=-3.40439025507934
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/280*10)=-1.22239242133645
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EMP2 [Title/Abstract] AND TERF2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEMP2(10637427)-TERF2(69419389), # samples:2
Anticipated loss of major functional domain due to fusion event.EMP2-TERF2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
EMP2-TERF2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
EMP2-TERF2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
EMP2-TERF2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneEMP2

GO:0001954

positive regulation of cell-matrix adhesion

16216233

HgeneEMP2

GO:0003093

regulation of glomerular filtration

24814193

HgeneEMP2

GO:0007015

actin filament organization

19494199

HgeneEMP2

GO:0007155

cell adhesion

19494199

HgeneEMP2

GO:0007160

cell-matrix adhesion

19494199

HgeneEMP2

GO:0008219

cell death

12107182

HgeneEMP2

GO:0008283

cell proliferation

21637765

HgeneEMP2

GO:0010594

regulation of endothelial cell migration

23334331

HgeneEMP2

GO:0016477

cell migration

21637765

HgeneEMP2

GO:0032060

bleb assembly

12107182

HgeneEMP2

GO:0032147

activation of protein kinase activity

21637765

HgeneEMP2

GO:0043534

blood vessel endothelial cell migration

23439602

HgeneEMP2

GO:0043549

regulation of kinase activity

18469192

HgeneEMP2

GO:0045765

regulation of angiogenesis

23334331

HgeneEMP2

GO:0070252

actin-mediated cell contraction

18469192|22728127

HgeneEMP2

GO:2001046

positive regulation of integrin-mediated signaling pathway

16216233

HgeneEMP2

GO:2001212

regulation of vasculogenesis

23334331

TgeneTERF2

GO:0031627

telomeric loop formation

10338214

TgeneTERF2

GO:0032205

negative regulation of telomere maintenance

17055345

TgeneTERF2

GO:0032210

regulation of telomere maintenance via telomerase

23685356

TgeneTERF2

GO:0032211

negative regulation of telomere maintenance via telomerase

17055345

TgeneTERF2

GO:1903770

negative regulation of beta-galactosidase activity

11927518

TgeneTERF2

GO:1905778

negative regulation of exonuclease activity

15200954

TgeneTERF2

GO:1905839

negative regulation of telomeric D-loop disassembly

15200954


check buttonFusion gene breakpoints across EMP2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across TERF2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-77-7463-01AEMP2chr16

10637427

-TERF2chr16

69419389

-
ChimerDB4LUSCTCGA-77-7463EMP2chr16

10637426

-TERF2chr16

69419389

-
ChimerDB4LUSCTCGA-77-7463EMP2chr16

10637427

-TERF2chr16

69419389

-


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Fusion Gene ORF analysis for EMP2-TERF2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000359543ENST00000567296EMP2chr16

10637427

-TERF2chr16

69419389

-
5CDS-5UTRENST00000359543ENST00000567296EMP2chr16

10637426

-TERF2chr16

69419389

-
5CDS-5UTRENST00000359543ENST00000569611EMP2chr16

10637427

-TERF2chr16

69419389

-
5CDS-5UTRENST00000359543ENST00000569611EMP2chr16

10637426

-TERF2chr16

69419389

-
5CDS-5UTRENST00000536829ENST00000567296EMP2chr16

10637427

-TERF2chr16

69419389

-
5CDS-5UTRENST00000536829ENST00000567296EMP2chr16

10637426

-TERF2chr16

69419389

-
5CDS-5UTRENST00000536829ENST00000569611EMP2chr16

10637427

-TERF2chr16

69419389

-
5CDS-5UTRENST00000536829ENST00000569611EMP2chr16

10637426

-TERF2chr16

69419389

-
In-frameENST00000359543ENST00000254942EMP2chr16

10637427

-TERF2chr16

69419389

-
In-frameENST00000359543ENST00000254942EMP2chr16

10637426

-TERF2chr16

69419389

-
In-frameENST00000359543ENST00000603068EMP2chr16

10637427

-TERF2chr16

69419389

-
In-frameENST00000359543ENST00000603068EMP2chr16

10637426

-TERF2chr16

69419389

-
In-frameENST00000536829ENST00000254942EMP2chr16

10637427

-TERF2chr16

69419389

-
In-frameENST00000536829ENST00000254942EMP2chr16

10637426

-TERF2chr16

69419389

-
In-frameENST00000536829ENST00000603068EMP2chr16

10637427

-TERF2chr16

69419389

-
In-frameENST00000536829ENST00000603068EMP2chr16

10637426

-TERF2chr16

69419389

-
intron-3CDSENST00000566033ENST00000254942EMP2chr16

10637427

-TERF2chr16

69419389

-
intron-3CDSENST00000566033ENST00000254942EMP2chr16

10637426

-TERF2chr16

69419389

-
intron-3CDSENST00000566033ENST00000603068EMP2chr16

10637427

-TERF2chr16

69419389

-
intron-3CDSENST00000566033ENST00000603068EMP2chr16

10637426

-TERF2chr16

69419389

-
intron-5UTRENST00000566033ENST00000567296EMP2chr16

10637427

-TERF2chr16

69419389

-
intron-5UTRENST00000566033ENST00000567296EMP2chr16

10637426

-TERF2chr16

69419389

-
intron-5UTRENST00000566033ENST00000569611EMP2chr16

10637427

-TERF2chr16

69419389

-
intron-5UTRENST00000566033ENST00000569611EMP2chr16

10637426

-TERF2chr16

69419389

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000359543EMP2chr1610637427-ENST00000254942TERF2chr1669419389-29663792101628472
ENST00000359543EMP2chr1610637427-ENST00000603068TERF2chr1669419389-28953792101628472
ENST00000536829EMP2chr1610637427-ENST00000254942TERF2chr1669419389-29773901281639503
ENST00000536829EMP2chr1610637427-ENST00000603068TERF2chr1669419389-29063901281639503
ENST00000359543EMP2chr1610637426-ENST00000254942TERF2chr1669419389-29663792101628472
ENST00000359543EMP2chr1610637426-ENST00000603068TERF2chr1669419389-28953792101628472
ENST00000536829EMP2chr1610637426-ENST00000254942TERF2chr1669419389-29773901281639503
ENST00000536829EMP2chr1610637426-ENST00000603068TERF2chr1669419389-29063901281639503

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000359543ENST00000254942EMP2chr1610637427-TERF2chr1669419389-0.001162860.9988372
ENST00000359543ENST00000603068EMP2chr1610637427-TERF2chr1669419389-0.0012493730.99875057
ENST00000536829ENST00000254942EMP2chr1610637427-TERF2chr1669419389-0.0011787070.9988213
ENST00000536829ENST00000603068EMP2chr1610637427-TERF2chr1669419389-0.0012626130.9987374
ENST00000359543ENST00000254942EMP2chr1610637426-TERF2chr1669419389-0.001162860.9988372
ENST00000359543ENST00000603068EMP2chr1610637426-TERF2chr1669419389-0.0012493730.99875057
ENST00000536829ENST00000254942EMP2chr1610637426-TERF2chr1669419389-0.0011787070.9988213
ENST00000536829ENST00000603068EMP2chr1610637426-TERF2chr1669419389-0.0012626130.9987374

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Fusion Genomic Features for EMP2-TERF2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for EMP2-TERF2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:10637427/chr16:69419389)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEMP2chr16:10637426chr16:69419389ENST00000359543-351_2156168.0TransmembraneHelical
HgeneEMP2chr16:10637426chr16:69419389ENST00000536829-351_2156168.0TransmembraneHelical
HgeneEMP2chr16:10637427chr16:69419389ENST00000359543-351_2156168.0TransmembraneHelical
HgeneEMP2chr16:10637427chr16:69419389ENST00000536829-351_2156168.0TransmembraneHelical
TgeneTERF2chr16:10637426chr16:69419389ENST00000254942010512_537126543.0DNA bindingH-T-H motif
TgeneTERF2chr16:10637426chr16:69419389ENST00000603068010512_53784501.0DNA bindingH-T-H motif
TgeneTERF2chr16:10637427chr16:69419389ENST00000254942010512_537126543.0DNA bindingH-T-H motif
TgeneTERF2chr16:10637427chr16:69419389ENST00000603068010512_53784501.0DNA bindingH-T-H motif
TgeneTERF2chr16:10637426chr16:69419389ENST00000254942010484_541126543.0DomainHTH myb-type
TgeneTERF2chr16:10637426chr16:69419389ENST00000603068010484_54184501.0DomainHTH myb-type
TgeneTERF2chr16:10637427chr16:69419389ENST00000254942010484_541126543.0DomainHTH myb-type
TgeneTERF2chr16:10637427chr16:69419389ENST00000603068010484_54184501.0DomainHTH myb-type
TgeneTERF2chr16:10637426chr16:69419389ENST00000254942010371_375126543.0MotifNuclear localization signal
TgeneTERF2chr16:10637426chr16:69419389ENST00000603068010371_37584501.0MotifNuclear localization signal
TgeneTERF2chr16:10637427chr16:69419389ENST00000254942010371_375126543.0MotifNuclear localization signal
TgeneTERF2chr16:10637427chr16:69419389ENST00000603068010371_37584501.0MotifNuclear localization signal
TgeneTERF2chr16:10637426chr16:69419389ENST0000060306801084_28784501.0RegionNote=TRFH dimerization
TgeneTERF2chr16:10637427chr16:69419389ENST0000060306801084_28784501.0RegionNote=TRFH dimerization

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEMP2chr16:10637426chr16:69419389ENST00000359543-35143_16356168.0TransmembraneHelical
HgeneEMP2chr16:10637426chr16:69419389ENST00000359543-3567_8756168.0TransmembraneHelical
HgeneEMP2chr16:10637426chr16:69419389ENST00000359543-3595_11556168.0TransmembraneHelical
HgeneEMP2chr16:10637426chr16:69419389ENST00000536829-35143_16356168.0TransmembraneHelical
HgeneEMP2chr16:10637426chr16:69419389ENST00000536829-3567_8756168.0TransmembraneHelical
HgeneEMP2chr16:10637426chr16:69419389ENST00000536829-3595_11556168.0TransmembraneHelical
HgeneEMP2chr16:10637427chr16:69419389ENST00000359543-35143_16356168.0TransmembraneHelical
HgeneEMP2chr16:10637427chr16:69419389ENST00000359543-3567_8756168.0TransmembraneHelical
HgeneEMP2chr16:10637427chr16:69419389ENST00000359543-3595_11556168.0TransmembraneHelical
HgeneEMP2chr16:10637427chr16:69419389ENST00000536829-35143_16356168.0TransmembraneHelical
HgeneEMP2chr16:10637427chr16:69419389ENST00000536829-3567_8756168.0TransmembraneHelical
HgeneEMP2chr16:10637427chr16:69419389ENST00000536829-3595_11556168.0TransmembraneHelical
TgeneTERF2chr16:10637426chr16:69419389ENST0000025494201055_72126543.0Compositional biasNote=Arg-rich (basic)
TgeneTERF2chr16:10637426chr16:69419389ENST0000060306801055_7284501.0Compositional biasNote=Arg-rich (basic)
TgeneTERF2chr16:10637427chr16:69419389ENST0000025494201055_72126543.0Compositional biasNote=Arg-rich (basic)
TgeneTERF2chr16:10637427chr16:69419389ENST0000060306801055_7284501.0Compositional biasNote=Arg-rich (basic)
TgeneTERF2chr16:10637426chr16:69419389ENST0000025494201084_287126543.0RegionNote=TRFH dimerization
TgeneTERF2chr16:10637427chr16:69419389ENST0000025494201084_287126543.0RegionNote=TRFH dimerization


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Fusion Gene Sequence for EMP2-TERF2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>26505_26505_1_EMP2-TERF2_EMP2_chr16_10637426_ENST00000359543_TERF2_chr16_69419389_ENST00000254942_length(transcript)=2966nt_BP=379nt
GGCGGGATCGGGGAAGGAGGGGCCCCGCCGCCTAGAGGGTGGAGGGAGGGCGCGCAGTCCCAGCCCAGAGCTTCAAAACAGCCCGGCGGC
CTCGCCTCGCACCCCCAGCCAGTCCGTCGATCCAGCTGCCAGCGCAGCCGCCAGCGCCGGCACATCCCGCTCTGGGCTTTAAACGTGACC
CCTCGCCTCGACTCGCCCTGCCCTGTGAAAATGTTGGTGCTTCTTGCTTTCATCATCGCCTTCCACATCACCTCTGCAGCCTTGCTGTTC
ATTGCCACCGTCGACAATGCCTGGTGGGTAGGAGATGAGTTTTTTGCAGATGTCTGGAGAATATGTACCAACAACACGAATTGCACAGTC
ATCAATGACAGCTTTCAAGCTTTGCTTGTCAGGCCCTTGGGGAAGGAGCACACCGTGTCCCGATTGCTGCGGGTTATGCAGTGTCTGTCG
CGGATTGAAGAAGGGGAAAATTTAGACTGTTCCTTTGATATGGAGGCTGAGCTCACACCACTGGAATCAGCTATCAATGTGCTGGAGATG
ATTAAAACGGAATTTACACTGACAGAAGCAGTGGTCGAATCCAGTAGAAAACTGGTCAAGGAAGCTGCTGTCATTATTTGTATCAAAAAC
AAAGAATTTGAAAAGGCTTCAAAAATTTTGAAAAAACATATGTCCAAGGACCCCACAACTCAGAAGCTGAGAAATGATCTCCTGAATATT
ATTCGAGAAAAGAACTTGGCCCATCCTGTTATCCAGAACTTTTCATATGAGACCTTCCAGCAGAAGATGCTGCGCTTCCTGGAGAGCCAC
CTGGATGACGCCGAGCCCTACCTCCTCACGATGGCCAAAAAGGCTTTGAAATCTGAGTCCGCTGCCTCAAGTACAGGGAAGGAAGATAAA
CAGCCAGCACCAGGGCCTGTGGAAAAGCCACCCAGAGAACCCGCAAGGCAGCTACGGAATCCTCCAACCACCATTGGAATGATGACTCTG
AAAGCAGCTTTCAAGACTCTGTCTGGTGCACAGGATTCTGAGGCAGCCTTTGCAAAACTGGACCAGAAGGATCTGGTTCTTCCTACTCAA
GCTCTCCCAGCATCACCAGCCCTCAAAAACAAGAGACCCAGAAAAGATGAAAACGAAAGTTCAGCCCCGGCTGACGGTGAGGGTGGCTCG
GAACTGCAGCCCAAGAACAAGCGCATGACAATAAGCAGATTGGTCTTGGAGGAGGACAGCCAGAGTACTGAGCCCAGCGCAGGCCTCAAC
TCCTCCCAGGAGGCCGCTTCAGCGCCACCATCCAAGCCCACCGTTCTCAACCAACCCCTCCCTGGAGAGAAGAATCCCAAAGTACCCAAA
GGCAAGTGGAACAGCTCTAATGGGGTTGAAGAAAAGGAGACTTGGGTGGAAGAGGATGAACTGTTTCAAGTTCAGGCAGCACCAGATGAA
GACAGTACAACCAATATAACAAAAAAGCAGAAGTGGACTGTAGAAGAAAGCGAGTGGGTCAAGGCTGGAGTGCAGAAATATGGGGAAGGA
AACTGGGCTGCCATTTCTAAAAATTACCCATTTGTTAACCGAACAGCTGTGATGATTAAGGATCGCTGGCGGACCATGAAAAGACTTGGC
ATGAACTGAAACAGGCTTTCATTTCCACAGAATTCACAGGAGCATGGTTCCTAATAATAGCCCCTGATAGTCTGCTCTTTCTTTCTTTTT
CTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCGACCTCCGTCTC
CCGGGCTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCATCACGCCCGGCTAATGTTTTGTATTTTT
AGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCAACTCGGCCTCCCAAAGTGCTGGGA
TTACAGGCATGAGCCACCGCGCCTGGCATCTGCTGTTTCTTTCAGAAGCTGGGCTGGGATGAGAATTTTGGGCAACCTCCTTCGACGTGG
GGGAGGTCCCATTTCCACTTCATCACTGTTGGAGATCATGGAGCTAAGAAGCAGAGCCAAGTCCACCCATGTCCTTGGCAGAGATGACAG
GCACACAGCTTGTGCAGTGCCAGAATATCATTAGCGTTTCCCTTCTTTAGTGGTTTGCTTAAATTTAAATCCCTGGTAATCTGTAGAACC
TTCTCCTAGGAAATGGTGAAGTCTATTAGGAGCCACTTGTGACTCCATGACCTGTTAAAACCAGCAATGTGAGTATTATTTGGAGTAAAT
TTGTTCCACGTCAAGTTCTGGCCTTCTGATGCAAATGCAAAGGAACTTAGTCTGTTATGAACCCAGGTTGATGACAGACCAGTCCTTGTG
GAATAAGATTCCCTTTAAAAACTCTTTAGCCAGTCGTGACATCAACCCTAGACCTGTCTGCCTTGGCATTTGCTGTCAACATCTGCTGGG
CTATGTAGGCAGGTTAATCCTCCACTTCTCATGTGGTTGAACCAGTGTGTTTTTTGGTAAAATGGTGATTGTAGATAAGATTAGTTCCCT
GATCCCCTGCCCCCTGTCCCCTGCCTCTTTTCCCAATTCCCTTCCTTATGCTGGACTTTTAAAGCTTAAAAAAAATCCGATTGAATATAA
ATGCCTAATTTCATTCTTTGTGAAATGGTTGCTTCCTCCTGATTCCCTAATTGTGCTGTGTTCGTGTCTTGCACTGGAATTCAACATTCC
CTTCTCCTTTTGTACTGTGTTGTGCTTGCTGTCTCTCCCGGACACCCTTAAAGACTGTCTTTTTAGCAAAAAATTTCAGTAAAGTGTTTT

>26505_26505_1_EMP2-TERF2_EMP2_chr16_10637426_ENST00000359543_TERF2_chr16_69419389_ENST00000254942_length(amino acids)=472AA_BP=56
MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDSFQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDC
SFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPV
IQNFSYETFQQKMLRFLESHLDDAEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGA
QDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPP
SKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYP

--------------------------------------------------------------
>26505_26505_2_EMP2-TERF2_EMP2_chr16_10637426_ENST00000359543_TERF2_chr16_69419389_ENST00000603068_length(transcript)=2895nt_BP=379nt
GGCGGGATCGGGGAAGGAGGGGCCCCGCCGCCTAGAGGGTGGAGGGAGGGCGCGCAGTCCCAGCCCAGAGCTTCAAAACAGCCCGGCGGC
CTCGCCTCGCACCCCCAGCCAGTCCGTCGATCCAGCTGCCAGCGCAGCCGCCAGCGCCGGCACATCCCGCTCTGGGCTTTAAACGTGACC
CCTCGCCTCGACTCGCCCTGCCCTGTGAAAATGTTGGTGCTTCTTGCTTTCATCATCGCCTTCCACATCACCTCTGCAGCCTTGCTGTTC
ATTGCCACCGTCGACAATGCCTGGTGGGTAGGAGATGAGTTTTTTGCAGATGTCTGGAGAATATGTACCAACAACACGAATTGCACAGTC
ATCAATGACAGCTTTCAAGCTTTGCTTGTCAGGCCCTTGGGGAAGGAGCACACCGTGTCCCGATTGCTGCGGGTTATGCAGTGTCTGTCG
CGGATTGAAGAAGGGGAAAATTTAGACTGTTCCTTTGATATGGAGGCTGAGCTCACACCACTGGAATCAGCTATCAATGTGCTGGAGATG
ATTAAAACGGAATTTACACTGACAGAAGCAGTGGTCGAATCCAGTAGAAAACTGGTCAAGGAAGCTGCTGTCATTATTTGTATCAAAAAC
AAAGAATTTGAAAAGGCTTCAAAAATTTTGAAAAAACATATGTCCAAGGACCCCACAACTCAGAAGCTGAGAAATGATCTCCTGAATATT
ATTCGAGAAAAGAACTTGGCCCATCCTGTTATCCAGAACTTTTCATATGAGACCTTCCAGCAGAAGATGCTGCGCTTCCTGGAGAGCCAC
CTGGATGACGCCGAGCCCTACCTCCTCACGATGGCCAAAAAGGCTTTGAAATCTGAGTCCGCTGCCTCAAGTACAGGGAAGGAAGATAAA
CAGCCAGCACCAGGGCCTGTGGAAAAGCCACCCAGAGAACCCGCAAGGCAGCTACGGAATCCTCCAACCACCATTGGAATGATGACTCTG
AAAGCAGCTTTCAAGACTCTGTCTGGTGCACAGGATTCTGAGGCAGCCTTTGCAAAACTGGACCAGAAGGATCTGGTTCTTCCTACTCAA
GCTCTCCCAGCATCACCAGCCCTCAAAAACAAGAGACCCAGAAAAGATGAAAACGAAAGTTCAGCCCCGGCTGACGGTGAGGGTGGCTCG
GAACTGCAGCCCAAGAACAAGCGCATGACAATAAGCAGATTGGTCTTGGAGGAGGACAGCCAGAGTACTGAGCCCAGCGCAGGCCTCAAC
TCCTCCCAGGAGGCCGCTTCAGCGCCACCATCCAAGCCCACCGTTCTCAACCAACCCCTCCCTGGAGAGAAGAATCCCAAAGTACCCAAA
GGCAAGTGGAACAGCTCTAATGGGGTTGAAGAAAAGGAGACTTGGGTGGAAGAGGATGAACTGTTTCAAGTTCAGGCAGCACCAGATGAA
GACAGTACAACCAATATAACAAAAAAGCAGAAGTGGACTGTAGAAGAAAGCGAGTGGGTCAAGGCTGGAGTGCAGAAATATGGGGAAGGA
AACTGGGCTGCCATTTCTAAAAATTACCCATTTGTTAACCGAACAGCTGTGATGATTAAGGATCGCTGGCGGACCATGAAAAGACTTGGC
ATGAACTGAAACAGGCTTTCATTTCCACAGAATTCACAGGAGCATGGTTCCTAATAATAGCCCCTGATAGTCTGCTCTTTCTTTCTTTTT
CTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCGACCTCCGTCTC
CCGGGCTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCATCACGCCCGGCTAATGTTTTGTATTTTT
AGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCAACTCGGCCTCCCAAAGTGCTGGGA
TTACAGGCATGAGCCACCGCGCCTGGCATCTGCTGTTTCTTTCAGAAGCTGGGCTGGGATGAGAATTTTGGGCAACCTCCTTCGACGTGG
GGGAGGTCCCATTTCCACTTCATCACTGTTGGAGATCATGGAGCTAAGAAGCAGAGCCAAGTCCACCCATGTCCTTGGCAGAGATGACAG
GCACACAGCTTGTGCAGTGCCAGAATATCATTAGCGTTTCCCTTCTTTAGTGGTTTGCTTAAATTTAAATCCCTGGTAATCTGTAGAACC
TTCTCCTAGGAAATGGTGAAGTCTATTAGGAGCCACTTGTGACTCCATGACCTGTTAAAACCAGCAATGTGAGTATTATTTGGAGTAAAT
TTGTTCCACGTCAAGTTCTGGCCTTCTGATGCAAATGCAAAGGAACTTAGTCTGTTATGAACCCAGGTTGATGACAGACCAGTCCTTGTG
GAATAAGATTCCCTTTAAAAACTCTTTAGCCAGTCGTGACATCAACCCTAGACCTGTCTGCCTTGGCATTTGCTGTCAACATCTGCTGGG
CTATGTAGGCAGGTTAATCCTCCACTTCTCATGTGGTTGAACCAGTGTGTTTTTTGGTAAAATGGTGATTGTAGATAAGATTAGTTCCCT
GATCCCCTGCCCCCTGTCCCCTGCCTCTTTTCCCAATTCCCTTCCTTATGCTGGACTTTTAAAGCTTAAAAAAAATCCGATTGAATATAA
ATGCCTAATTTCATTCTTTGTGAAATGGTTGCTTCCTCCTGATTCCCTAATTGTGCTGTGTTCGTGTCTTGCACTGGAATTCAACATTCC
CTTCTCCTTTTGTACTGTGTTGTGCTTGCTGTCTCTCCCGGACACCCTTAAAGACTGTCTTTTTAGCAAAAAATTTCAGTAAAGTGTTTT

>26505_26505_2_EMP2-TERF2_EMP2_chr16_10637426_ENST00000359543_TERF2_chr16_69419389_ENST00000603068_length(amino acids)=472AA_BP=56
MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDSFQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDC
SFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPV
IQNFSYETFQQKMLRFLESHLDDAEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGA
QDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPP
SKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYP

--------------------------------------------------------------
>26505_26505_3_EMP2-TERF2_EMP2_chr16_10637426_ENST00000536829_TERF2_chr16_69419389_ENST00000254942_length(transcript)=2977nt_BP=390nt
GGCCTGGGAGTCCTTGCAGGGTGGCCTGGGTGACTGCTCACCAGCCCGGCCCTCCCCAGGGTTCTGGGCCAGAGCCTCCCTGGCCGTTGG
AGCGGGAGCTGTGGGTGGAACACTTCTGAATTGGGAGATTGCCTCGGACCTCCAGACGCCGAACATCTCAGCACATCCCGCTCTGGGCTT
TAAACGTGACCCCTCGCCTCGACTCGCCCTGCCCTGTGAAAATGTTGGTGCTTCTTGCTTTCATCATCGCCTTCCACATCACCTCTGCAG
CCTTGCTGTTCATTGCCACCGTCGACAATGCCTGGTGGGTAGGAGATGAGTTTTTTGCAGATGTCTGGAGAATATGTACCAACAACACGA
ATTGCACAGTCATCAATGACAGCTTTCAAGCTTTGCTTGTCAGGCCCTTGGGGAAGGAGCACACCGTGTCCCGATTGCTGCGGGTTATGC
AGTGTCTGTCGCGGATTGAAGAAGGGGAAAATTTAGACTGTTCCTTTGATATGGAGGCTGAGCTCACACCACTGGAATCAGCTATCAATG
TGCTGGAGATGATTAAAACGGAATTTACACTGACAGAAGCAGTGGTCGAATCCAGTAGAAAACTGGTCAAGGAAGCTGCTGTCATTATTT
GTATCAAAAACAAAGAATTTGAAAAGGCTTCAAAAATTTTGAAAAAACATATGTCCAAGGACCCCACAACTCAGAAGCTGAGAAATGATC
TCCTGAATATTATTCGAGAAAAGAACTTGGCCCATCCTGTTATCCAGAACTTTTCATATGAGACCTTCCAGCAGAAGATGCTGCGCTTCC
TGGAGAGCCACCTGGATGACGCCGAGCCCTACCTCCTCACGATGGCCAAAAAGGCTTTGAAATCTGAGTCCGCTGCCTCAAGTACAGGGA
AGGAAGATAAACAGCCAGCACCAGGGCCTGTGGAAAAGCCACCCAGAGAACCCGCAAGGCAGCTACGGAATCCTCCAACCACCATTGGAA
TGATGACTCTGAAAGCAGCTTTCAAGACTCTGTCTGGTGCACAGGATTCTGAGGCAGCCTTTGCAAAACTGGACCAGAAGGATCTGGTTC
TTCCTACTCAAGCTCTCCCAGCATCACCAGCCCTCAAAAACAAGAGACCCAGAAAAGATGAAAACGAAAGTTCAGCCCCGGCTGACGGTG
AGGGTGGCTCGGAACTGCAGCCCAAGAACAAGCGCATGACAATAAGCAGATTGGTCTTGGAGGAGGACAGCCAGAGTACTGAGCCCAGCG
CAGGCCTCAACTCCTCCCAGGAGGCCGCTTCAGCGCCACCATCCAAGCCCACCGTTCTCAACCAACCCCTCCCTGGAGAGAAGAATCCCA
AAGTACCCAAAGGCAAGTGGAACAGCTCTAATGGGGTTGAAGAAAAGGAGACTTGGGTGGAAGAGGATGAACTGTTTCAAGTTCAGGCAG
CACCAGATGAAGACAGTACAACCAATATAACAAAAAAGCAGAAGTGGACTGTAGAAGAAAGCGAGTGGGTCAAGGCTGGAGTGCAGAAAT
ATGGGGAAGGAAACTGGGCTGCCATTTCTAAAAATTACCCATTTGTTAACCGAACAGCTGTGATGATTAAGGATCGCTGGCGGACCATGA
AAAGACTTGGCATGAACTGAAACAGGCTTTCATTTCCACAGAATTCACAGGAGCATGGTTCCTAATAATAGCCCCTGATAGTCTGCTCTT
TCTTTCTTTTTCTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCG
ACCTCCGTCTCCCGGGCTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCATCACGCCCGGCTAATGT
TTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCAACTCGGCCTCCCA
AAGTGCTGGGATTACAGGCATGAGCCACCGCGCCTGGCATCTGCTGTTTCTTTCAGAAGCTGGGCTGGGATGAGAATTTTGGGCAACCTC
CTTCGACGTGGGGGAGGTCCCATTTCCACTTCATCACTGTTGGAGATCATGGAGCTAAGAAGCAGAGCCAAGTCCACCCATGTCCTTGGC
AGAGATGACAGGCACACAGCTTGTGCAGTGCCAGAATATCATTAGCGTTTCCCTTCTTTAGTGGTTTGCTTAAATTTAAATCCCTGGTAA
TCTGTAGAACCTTCTCCTAGGAAATGGTGAAGTCTATTAGGAGCCACTTGTGACTCCATGACCTGTTAAAACCAGCAATGTGAGTATTAT
TTGGAGTAAATTTGTTCCACGTCAAGTTCTGGCCTTCTGATGCAAATGCAAAGGAACTTAGTCTGTTATGAACCCAGGTTGATGACAGAC
CAGTCCTTGTGGAATAAGATTCCCTTTAAAAACTCTTTAGCCAGTCGTGACATCAACCCTAGACCTGTCTGCCTTGGCATTTGCTGTCAA
CATCTGCTGGGCTATGTAGGCAGGTTAATCCTCCACTTCTCATGTGGTTGAACCAGTGTGTTTTTTGGTAAAATGGTGATTGTAGATAAG
ATTAGTTCCCTGATCCCCTGCCCCCTGTCCCCTGCCTCTTTTCCCAATTCCCTTCCTTATGCTGGACTTTTAAAGCTTAAAAAAAATCCG
ATTGAATATAAATGCCTAATTTCATTCTTTGTGAAATGGTTGCTTCCTCCTGATTCCCTAATTGTGCTGTGTTCGTGTCTTGCACTGGAA
TTCAACATTCCCTTCTCCTTTTGTACTGTGTTGTGCTTGCTGTCTCTCCCGGACACCCTTAAAGACTGTCTTTTTAGCAAAAAATTTCAG
TAAAGTGTTTTCTGTAATCTTTTTTTAAAAGGTGAGAACTAATTATTGTCCATACTTGTAGCATTCTTCATTAAAGTCTTGCTTCTCTCA

>26505_26505_3_EMP2-TERF2_EMP2_chr16_10637426_ENST00000536829_TERF2_chr16_69419389_ENST00000254942_length(amino acids)=503AA_BP=87
MPRTSRRRTSQHIPLWALNVTPRLDSPCPVKMLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDSFQALL
VRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKI
LKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRFLESHLDDAEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEK
PPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRM
TISRLVLEEDSQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKK

--------------------------------------------------------------
>26505_26505_4_EMP2-TERF2_EMP2_chr16_10637426_ENST00000536829_TERF2_chr16_69419389_ENST00000603068_length(transcript)=2906nt_BP=390nt
GGCCTGGGAGTCCTTGCAGGGTGGCCTGGGTGACTGCTCACCAGCCCGGCCCTCCCCAGGGTTCTGGGCCAGAGCCTCCCTGGCCGTTGG
AGCGGGAGCTGTGGGTGGAACACTTCTGAATTGGGAGATTGCCTCGGACCTCCAGACGCCGAACATCTCAGCACATCCCGCTCTGGGCTT
TAAACGTGACCCCTCGCCTCGACTCGCCCTGCCCTGTGAAAATGTTGGTGCTTCTTGCTTTCATCATCGCCTTCCACATCACCTCTGCAG
CCTTGCTGTTCATTGCCACCGTCGACAATGCCTGGTGGGTAGGAGATGAGTTTTTTGCAGATGTCTGGAGAATATGTACCAACAACACGA
ATTGCACAGTCATCAATGACAGCTTTCAAGCTTTGCTTGTCAGGCCCTTGGGGAAGGAGCACACCGTGTCCCGATTGCTGCGGGTTATGC
AGTGTCTGTCGCGGATTGAAGAAGGGGAAAATTTAGACTGTTCCTTTGATATGGAGGCTGAGCTCACACCACTGGAATCAGCTATCAATG
TGCTGGAGATGATTAAAACGGAATTTACACTGACAGAAGCAGTGGTCGAATCCAGTAGAAAACTGGTCAAGGAAGCTGCTGTCATTATTT
GTATCAAAAACAAAGAATTTGAAAAGGCTTCAAAAATTTTGAAAAAACATATGTCCAAGGACCCCACAACTCAGAAGCTGAGAAATGATC
TCCTGAATATTATTCGAGAAAAGAACTTGGCCCATCCTGTTATCCAGAACTTTTCATATGAGACCTTCCAGCAGAAGATGCTGCGCTTCC
TGGAGAGCCACCTGGATGACGCCGAGCCCTACCTCCTCACGATGGCCAAAAAGGCTTTGAAATCTGAGTCCGCTGCCTCAAGTACAGGGA
AGGAAGATAAACAGCCAGCACCAGGGCCTGTGGAAAAGCCACCCAGAGAACCCGCAAGGCAGCTACGGAATCCTCCAACCACCATTGGAA
TGATGACTCTGAAAGCAGCTTTCAAGACTCTGTCTGGTGCACAGGATTCTGAGGCAGCCTTTGCAAAACTGGACCAGAAGGATCTGGTTC
TTCCTACTCAAGCTCTCCCAGCATCACCAGCCCTCAAAAACAAGAGACCCAGAAAAGATGAAAACGAAAGTTCAGCCCCGGCTGACGGTG
AGGGTGGCTCGGAACTGCAGCCCAAGAACAAGCGCATGACAATAAGCAGATTGGTCTTGGAGGAGGACAGCCAGAGTACTGAGCCCAGCG
CAGGCCTCAACTCCTCCCAGGAGGCCGCTTCAGCGCCACCATCCAAGCCCACCGTTCTCAACCAACCCCTCCCTGGAGAGAAGAATCCCA
AAGTACCCAAAGGCAAGTGGAACAGCTCTAATGGGGTTGAAGAAAAGGAGACTTGGGTGGAAGAGGATGAACTGTTTCAAGTTCAGGCAG
CACCAGATGAAGACAGTACAACCAATATAACAAAAAAGCAGAAGTGGACTGTAGAAGAAAGCGAGTGGGTCAAGGCTGGAGTGCAGAAAT
ATGGGGAAGGAAACTGGGCTGCCATTTCTAAAAATTACCCATTTGTTAACCGAACAGCTGTGATGATTAAGGATCGCTGGCGGACCATGA
AAAGACTTGGCATGAACTGAAACAGGCTTTCATTTCCACAGAATTCACAGGAGCATGGTTCCTAATAATAGCCCCTGATAGTCTGCTCTT
TCTTTCTTTTTCTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCG
ACCTCCGTCTCCCGGGCTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCATCACGCCCGGCTAATGT
TTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCAACTCGGCCTCCCA
AAGTGCTGGGATTACAGGCATGAGCCACCGCGCCTGGCATCTGCTGTTTCTTTCAGAAGCTGGGCTGGGATGAGAATTTTGGGCAACCTC
CTTCGACGTGGGGGAGGTCCCATTTCCACTTCATCACTGTTGGAGATCATGGAGCTAAGAAGCAGAGCCAAGTCCACCCATGTCCTTGGC
AGAGATGACAGGCACACAGCTTGTGCAGTGCCAGAATATCATTAGCGTTTCCCTTCTTTAGTGGTTTGCTTAAATTTAAATCCCTGGTAA
TCTGTAGAACCTTCTCCTAGGAAATGGTGAAGTCTATTAGGAGCCACTTGTGACTCCATGACCTGTTAAAACCAGCAATGTGAGTATTAT
TTGGAGTAAATTTGTTCCACGTCAAGTTCTGGCCTTCTGATGCAAATGCAAAGGAACTTAGTCTGTTATGAACCCAGGTTGATGACAGAC
CAGTCCTTGTGGAATAAGATTCCCTTTAAAAACTCTTTAGCCAGTCGTGACATCAACCCTAGACCTGTCTGCCTTGGCATTTGCTGTCAA
CATCTGCTGGGCTATGTAGGCAGGTTAATCCTCCACTTCTCATGTGGTTGAACCAGTGTGTTTTTTGGTAAAATGGTGATTGTAGATAAG
ATTAGTTCCCTGATCCCCTGCCCCCTGTCCCCTGCCTCTTTTCCCAATTCCCTTCCTTATGCTGGACTTTTAAAGCTTAAAAAAAATCCG
ATTGAATATAAATGCCTAATTTCATTCTTTGTGAAATGGTTGCTTCCTCCTGATTCCCTAATTGTGCTGTGTTCGTGTCTTGCACTGGAA
TTCAACATTCCCTTCTCCTTTTGTACTGTGTTGTGCTTGCTGTCTCTCCCGGACACCCTTAAAGACTGTCTTTTTAGCAAAAAATTTCAG

>26505_26505_4_EMP2-TERF2_EMP2_chr16_10637426_ENST00000536829_TERF2_chr16_69419389_ENST00000603068_length(amino acids)=503AA_BP=87
MPRTSRRRTSQHIPLWALNVTPRLDSPCPVKMLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDSFQALL
VRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKI
LKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRFLESHLDDAEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEK
PPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRM
TISRLVLEEDSQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKK

--------------------------------------------------------------
>26505_26505_5_EMP2-TERF2_EMP2_chr16_10637427_ENST00000359543_TERF2_chr16_69419389_ENST00000254942_length(transcript)=2966nt_BP=379nt
GGCGGGATCGGGGAAGGAGGGGCCCCGCCGCCTAGAGGGTGGAGGGAGGGCGCGCAGTCCCAGCCCAGAGCTTCAAAACAGCCCGGCGGC
CTCGCCTCGCACCCCCAGCCAGTCCGTCGATCCAGCTGCCAGCGCAGCCGCCAGCGCCGGCACATCCCGCTCTGGGCTTTAAACGTGACC
CCTCGCCTCGACTCGCCCTGCCCTGTGAAAATGTTGGTGCTTCTTGCTTTCATCATCGCCTTCCACATCACCTCTGCAGCCTTGCTGTTC
ATTGCCACCGTCGACAATGCCTGGTGGGTAGGAGATGAGTTTTTTGCAGATGTCTGGAGAATATGTACCAACAACACGAATTGCACAGTC
ATCAATGACAGCTTTCAAGCTTTGCTTGTCAGGCCCTTGGGGAAGGAGCACACCGTGTCCCGATTGCTGCGGGTTATGCAGTGTCTGTCG
CGGATTGAAGAAGGGGAAAATTTAGACTGTTCCTTTGATATGGAGGCTGAGCTCACACCACTGGAATCAGCTATCAATGTGCTGGAGATG
ATTAAAACGGAATTTACACTGACAGAAGCAGTGGTCGAATCCAGTAGAAAACTGGTCAAGGAAGCTGCTGTCATTATTTGTATCAAAAAC
AAAGAATTTGAAAAGGCTTCAAAAATTTTGAAAAAACATATGTCCAAGGACCCCACAACTCAGAAGCTGAGAAATGATCTCCTGAATATT
ATTCGAGAAAAGAACTTGGCCCATCCTGTTATCCAGAACTTTTCATATGAGACCTTCCAGCAGAAGATGCTGCGCTTCCTGGAGAGCCAC
CTGGATGACGCCGAGCCCTACCTCCTCACGATGGCCAAAAAGGCTTTGAAATCTGAGTCCGCTGCCTCAAGTACAGGGAAGGAAGATAAA
CAGCCAGCACCAGGGCCTGTGGAAAAGCCACCCAGAGAACCCGCAAGGCAGCTACGGAATCCTCCAACCACCATTGGAATGATGACTCTG
AAAGCAGCTTTCAAGACTCTGTCTGGTGCACAGGATTCTGAGGCAGCCTTTGCAAAACTGGACCAGAAGGATCTGGTTCTTCCTACTCAA
GCTCTCCCAGCATCACCAGCCCTCAAAAACAAGAGACCCAGAAAAGATGAAAACGAAAGTTCAGCCCCGGCTGACGGTGAGGGTGGCTCG
GAACTGCAGCCCAAGAACAAGCGCATGACAATAAGCAGATTGGTCTTGGAGGAGGACAGCCAGAGTACTGAGCCCAGCGCAGGCCTCAAC
TCCTCCCAGGAGGCCGCTTCAGCGCCACCATCCAAGCCCACCGTTCTCAACCAACCCCTCCCTGGAGAGAAGAATCCCAAAGTACCCAAA
GGCAAGTGGAACAGCTCTAATGGGGTTGAAGAAAAGGAGACTTGGGTGGAAGAGGATGAACTGTTTCAAGTTCAGGCAGCACCAGATGAA
GACAGTACAACCAATATAACAAAAAAGCAGAAGTGGACTGTAGAAGAAAGCGAGTGGGTCAAGGCTGGAGTGCAGAAATATGGGGAAGGA
AACTGGGCTGCCATTTCTAAAAATTACCCATTTGTTAACCGAACAGCTGTGATGATTAAGGATCGCTGGCGGACCATGAAAAGACTTGGC
ATGAACTGAAACAGGCTTTCATTTCCACAGAATTCACAGGAGCATGGTTCCTAATAATAGCCCCTGATAGTCTGCTCTTTCTTTCTTTTT
CTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCGACCTCCGTCTC
CCGGGCTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCATCACGCCCGGCTAATGTTTTGTATTTTT
AGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCAACTCGGCCTCCCAAAGTGCTGGGA
TTACAGGCATGAGCCACCGCGCCTGGCATCTGCTGTTTCTTTCAGAAGCTGGGCTGGGATGAGAATTTTGGGCAACCTCCTTCGACGTGG
GGGAGGTCCCATTTCCACTTCATCACTGTTGGAGATCATGGAGCTAAGAAGCAGAGCCAAGTCCACCCATGTCCTTGGCAGAGATGACAG
GCACACAGCTTGTGCAGTGCCAGAATATCATTAGCGTTTCCCTTCTTTAGTGGTTTGCTTAAATTTAAATCCCTGGTAATCTGTAGAACC
TTCTCCTAGGAAATGGTGAAGTCTATTAGGAGCCACTTGTGACTCCATGACCTGTTAAAACCAGCAATGTGAGTATTATTTGGAGTAAAT
TTGTTCCACGTCAAGTTCTGGCCTTCTGATGCAAATGCAAAGGAACTTAGTCTGTTATGAACCCAGGTTGATGACAGACCAGTCCTTGTG
GAATAAGATTCCCTTTAAAAACTCTTTAGCCAGTCGTGACATCAACCCTAGACCTGTCTGCCTTGGCATTTGCTGTCAACATCTGCTGGG
CTATGTAGGCAGGTTAATCCTCCACTTCTCATGTGGTTGAACCAGTGTGTTTTTTGGTAAAATGGTGATTGTAGATAAGATTAGTTCCCT
GATCCCCTGCCCCCTGTCCCCTGCCTCTTTTCCCAATTCCCTTCCTTATGCTGGACTTTTAAAGCTTAAAAAAAATCCGATTGAATATAA
ATGCCTAATTTCATTCTTTGTGAAATGGTTGCTTCCTCCTGATTCCCTAATTGTGCTGTGTTCGTGTCTTGCACTGGAATTCAACATTCC
CTTCTCCTTTTGTACTGTGTTGTGCTTGCTGTCTCTCCCGGACACCCTTAAAGACTGTCTTTTTAGCAAAAAATTTCAGTAAAGTGTTTT

>26505_26505_5_EMP2-TERF2_EMP2_chr16_10637427_ENST00000359543_TERF2_chr16_69419389_ENST00000254942_length(amino acids)=472AA_BP=56
MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDSFQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDC
SFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPV
IQNFSYETFQQKMLRFLESHLDDAEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGA
QDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPP
SKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYP

--------------------------------------------------------------
>26505_26505_6_EMP2-TERF2_EMP2_chr16_10637427_ENST00000359543_TERF2_chr16_69419389_ENST00000603068_length(transcript)=2895nt_BP=379nt
GGCGGGATCGGGGAAGGAGGGGCCCCGCCGCCTAGAGGGTGGAGGGAGGGCGCGCAGTCCCAGCCCAGAGCTTCAAAACAGCCCGGCGGC
CTCGCCTCGCACCCCCAGCCAGTCCGTCGATCCAGCTGCCAGCGCAGCCGCCAGCGCCGGCACATCCCGCTCTGGGCTTTAAACGTGACC
CCTCGCCTCGACTCGCCCTGCCCTGTGAAAATGTTGGTGCTTCTTGCTTTCATCATCGCCTTCCACATCACCTCTGCAGCCTTGCTGTTC
ATTGCCACCGTCGACAATGCCTGGTGGGTAGGAGATGAGTTTTTTGCAGATGTCTGGAGAATATGTACCAACAACACGAATTGCACAGTC
ATCAATGACAGCTTTCAAGCTTTGCTTGTCAGGCCCTTGGGGAAGGAGCACACCGTGTCCCGATTGCTGCGGGTTATGCAGTGTCTGTCG
CGGATTGAAGAAGGGGAAAATTTAGACTGTTCCTTTGATATGGAGGCTGAGCTCACACCACTGGAATCAGCTATCAATGTGCTGGAGATG
ATTAAAACGGAATTTACACTGACAGAAGCAGTGGTCGAATCCAGTAGAAAACTGGTCAAGGAAGCTGCTGTCATTATTTGTATCAAAAAC
AAAGAATTTGAAAAGGCTTCAAAAATTTTGAAAAAACATATGTCCAAGGACCCCACAACTCAGAAGCTGAGAAATGATCTCCTGAATATT
ATTCGAGAAAAGAACTTGGCCCATCCTGTTATCCAGAACTTTTCATATGAGACCTTCCAGCAGAAGATGCTGCGCTTCCTGGAGAGCCAC
CTGGATGACGCCGAGCCCTACCTCCTCACGATGGCCAAAAAGGCTTTGAAATCTGAGTCCGCTGCCTCAAGTACAGGGAAGGAAGATAAA
CAGCCAGCACCAGGGCCTGTGGAAAAGCCACCCAGAGAACCCGCAAGGCAGCTACGGAATCCTCCAACCACCATTGGAATGATGACTCTG
AAAGCAGCTTTCAAGACTCTGTCTGGTGCACAGGATTCTGAGGCAGCCTTTGCAAAACTGGACCAGAAGGATCTGGTTCTTCCTACTCAA
GCTCTCCCAGCATCACCAGCCCTCAAAAACAAGAGACCCAGAAAAGATGAAAACGAAAGTTCAGCCCCGGCTGACGGTGAGGGTGGCTCG
GAACTGCAGCCCAAGAACAAGCGCATGACAATAAGCAGATTGGTCTTGGAGGAGGACAGCCAGAGTACTGAGCCCAGCGCAGGCCTCAAC
TCCTCCCAGGAGGCCGCTTCAGCGCCACCATCCAAGCCCACCGTTCTCAACCAACCCCTCCCTGGAGAGAAGAATCCCAAAGTACCCAAA
GGCAAGTGGAACAGCTCTAATGGGGTTGAAGAAAAGGAGACTTGGGTGGAAGAGGATGAACTGTTTCAAGTTCAGGCAGCACCAGATGAA
GACAGTACAACCAATATAACAAAAAAGCAGAAGTGGACTGTAGAAGAAAGCGAGTGGGTCAAGGCTGGAGTGCAGAAATATGGGGAAGGA
AACTGGGCTGCCATTTCTAAAAATTACCCATTTGTTAACCGAACAGCTGTGATGATTAAGGATCGCTGGCGGACCATGAAAAGACTTGGC
ATGAACTGAAACAGGCTTTCATTTCCACAGAATTCACAGGAGCATGGTTCCTAATAATAGCCCCTGATAGTCTGCTCTTTCTTTCTTTTT
CTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCGACCTCCGTCTC
CCGGGCTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCATCACGCCCGGCTAATGTTTTGTATTTTT
AGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCAACTCGGCCTCCCAAAGTGCTGGGA
TTACAGGCATGAGCCACCGCGCCTGGCATCTGCTGTTTCTTTCAGAAGCTGGGCTGGGATGAGAATTTTGGGCAACCTCCTTCGACGTGG
GGGAGGTCCCATTTCCACTTCATCACTGTTGGAGATCATGGAGCTAAGAAGCAGAGCCAAGTCCACCCATGTCCTTGGCAGAGATGACAG
GCACACAGCTTGTGCAGTGCCAGAATATCATTAGCGTTTCCCTTCTTTAGTGGTTTGCTTAAATTTAAATCCCTGGTAATCTGTAGAACC
TTCTCCTAGGAAATGGTGAAGTCTATTAGGAGCCACTTGTGACTCCATGACCTGTTAAAACCAGCAATGTGAGTATTATTTGGAGTAAAT
TTGTTCCACGTCAAGTTCTGGCCTTCTGATGCAAATGCAAAGGAACTTAGTCTGTTATGAACCCAGGTTGATGACAGACCAGTCCTTGTG
GAATAAGATTCCCTTTAAAAACTCTTTAGCCAGTCGTGACATCAACCCTAGACCTGTCTGCCTTGGCATTTGCTGTCAACATCTGCTGGG
CTATGTAGGCAGGTTAATCCTCCACTTCTCATGTGGTTGAACCAGTGTGTTTTTTGGTAAAATGGTGATTGTAGATAAGATTAGTTCCCT
GATCCCCTGCCCCCTGTCCCCTGCCTCTTTTCCCAATTCCCTTCCTTATGCTGGACTTTTAAAGCTTAAAAAAAATCCGATTGAATATAA
ATGCCTAATTTCATTCTTTGTGAAATGGTTGCTTCCTCCTGATTCCCTAATTGTGCTGTGTTCGTGTCTTGCACTGGAATTCAACATTCC
CTTCTCCTTTTGTACTGTGTTGTGCTTGCTGTCTCTCCCGGACACCCTTAAAGACTGTCTTTTTAGCAAAAAATTTCAGTAAAGTGTTTT

>26505_26505_6_EMP2-TERF2_EMP2_chr16_10637427_ENST00000359543_TERF2_chr16_69419389_ENST00000603068_length(amino acids)=472AA_BP=56
MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDSFQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDC
SFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPV
IQNFSYETFQQKMLRFLESHLDDAEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGA
QDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPP
SKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYP

--------------------------------------------------------------
>26505_26505_7_EMP2-TERF2_EMP2_chr16_10637427_ENST00000536829_TERF2_chr16_69419389_ENST00000254942_length(transcript)=2977nt_BP=390nt
GGCCTGGGAGTCCTTGCAGGGTGGCCTGGGTGACTGCTCACCAGCCCGGCCCTCCCCAGGGTTCTGGGCCAGAGCCTCCCTGGCCGTTGG
AGCGGGAGCTGTGGGTGGAACACTTCTGAATTGGGAGATTGCCTCGGACCTCCAGACGCCGAACATCTCAGCACATCCCGCTCTGGGCTT
TAAACGTGACCCCTCGCCTCGACTCGCCCTGCCCTGTGAAAATGTTGGTGCTTCTTGCTTTCATCATCGCCTTCCACATCACCTCTGCAG
CCTTGCTGTTCATTGCCACCGTCGACAATGCCTGGTGGGTAGGAGATGAGTTTTTTGCAGATGTCTGGAGAATATGTACCAACAACACGA
ATTGCACAGTCATCAATGACAGCTTTCAAGCTTTGCTTGTCAGGCCCTTGGGGAAGGAGCACACCGTGTCCCGATTGCTGCGGGTTATGC
AGTGTCTGTCGCGGATTGAAGAAGGGGAAAATTTAGACTGTTCCTTTGATATGGAGGCTGAGCTCACACCACTGGAATCAGCTATCAATG
TGCTGGAGATGATTAAAACGGAATTTACACTGACAGAAGCAGTGGTCGAATCCAGTAGAAAACTGGTCAAGGAAGCTGCTGTCATTATTT
GTATCAAAAACAAAGAATTTGAAAAGGCTTCAAAAATTTTGAAAAAACATATGTCCAAGGACCCCACAACTCAGAAGCTGAGAAATGATC
TCCTGAATATTATTCGAGAAAAGAACTTGGCCCATCCTGTTATCCAGAACTTTTCATATGAGACCTTCCAGCAGAAGATGCTGCGCTTCC
TGGAGAGCCACCTGGATGACGCCGAGCCCTACCTCCTCACGATGGCCAAAAAGGCTTTGAAATCTGAGTCCGCTGCCTCAAGTACAGGGA
AGGAAGATAAACAGCCAGCACCAGGGCCTGTGGAAAAGCCACCCAGAGAACCCGCAAGGCAGCTACGGAATCCTCCAACCACCATTGGAA
TGATGACTCTGAAAGCAGCTTTCAAGACTCTGTCTGGTGCACAGGATTCTGAGGCAGCCTTTGCAAAACTGGACCAGAAGGATCTGGTTC
TTCCTACTCAAGCTCTCCCAGCATCACCAGCCCTCAAAAACAAGAGACCCAGAAAAGATGAAAACGAAAGTTCAGCCCCGGCTGACGGTG
AGGGTGGCTCGGAACTGCAGCCCAAGAACAAGCGCATGACAATAAGCAGATTGGTCTTGGAGGAGGACAGCCAGAGTACTGAGCCCAGCG
CAGGCCTCAACTCCTCCCAGGAGGCCGCTTCAGCGCCACCATCCAAGCCCACCGTTCTCAACCAACCCCTCCCTGGAGAGAAGAATCCCA
AAGTACCCAAAGGCAAGTGGAACAGCTCTAATGGGGTTGAAGAAAAGGAGACTTGGGTGGAAGAGGATGAACTGTTTCAAGTTCAGGCAG
CACCAGATGAAGACAGTACAACCAATATAACAAAAAAGCAGAAGTGGACTGTAGAAGAAAGCGAGTGGGTCAAGGCTGGAGTGCAGAAAT
ATGGGGAAGGAAACTGGGCTGCCATTTCTAAAAATTACCCATTTGTTAACCGAACAGCTGTGATGATTAAGGATCGCTGGCGGACCATGA
AAAGACTTGGCATGAACTGAAACAGGCTTTCATTTCCACAGAATTCACAGGAGCATGGTTCCTAATAATAGCCCCTGATAGTCTGCTCTT
TCTTTCTTTTTCTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCG
ACCTCCGTCTCCCGGGCTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCATCACGCCCGGCTAATGT
TTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCAACTCGGCCTCCCA
AAGTGCTGGGATTACAGGCATGAGCCACCGCGCCTGGCATCTGCTGTTTCTTTCAGAAGCTGGGCTGGGATGAGAATTTTGGGCAACCTC
CTTCGACGTGGGGGAGGTCCCATTTCCACTTCATCACTGTTGGAGATCATGGAGCTAAGAAGCAGAGCCAAGTCCACCCATGTCCTTGGC
AGAGATGACAGGCACACAGCTTGTGCAGTGCCAGAATATCATTAGCGTTTCCCTTCTTTAGTGGTTTGCTTAAATTTAAATCCCTGGTAA
TCTGTAGAACCTTCTCCTAGGAAATGGTGAAGTCTATTAGGAGCCACTTGTGACTCCATGACCTGTTAAAACCAGCAATGTGAGTATTAT
TTGGAGTAAATTTGTTCCACGTCAAGTTCTGGCCTTCTGATGCAAATGCAAAGGAACTTAGTCTGTTATGAACCCAGGTTGATGACAGAC
CAGTCCTTGTGGAATAAGATTCCCTTTAAAAACTCTTTAGCCAGTCGTGACATCAACCCTAGACCTGTCTGCCTTGGCATTTGCTGTCAA
CATCTGCTGGGCTATGTAGGCAGGTTAATCCTCCACTTCTCATGTGGTTGAACCAGTGTGTTTTTTGGTAAAATGGTGATTGTAGATAAG
ATTAGTTCCCTGATCCCCTGCCCCCTGTCCCCTGCCTCTTTTCCCAATTCCCTTCCTTATGCTGGACTTTTAAAGCTTAAAAAAAATCCG
ATTGAATATAAATGCCTAATTTCATTCTTTGTGAAATGGTTGCTTCCTCCTGATTCCCTAATTGTGCTGTGTTCGTGTCTTGCACTGGAA
TTCAACATTCCCTTCTCCTTTTGTACTGTGTTGTGCTTGCTGTCTCTCCCGGACACCCTTAAAGACTGTCTTTTTAGCAAAAAATTTCAG
TAAAGTGTTTTCTGTAATCTTTTTTTAAAAGGTGAGAACTAATTATTGTCCATACTTGTAGCATTCTTCATTAAAGTCTTGCTTCTCTCA

>26505_26505_7_EMP2-TERF2_EMP2_chr16_10637427_ENST00000536829_TERF2_chr16_69419389_ENST00000254942_length(amino acids)=503AA_BP=87
MPRTSRRRTSQHIPLWALNVTPRLDSPCPVKMLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDSFQALL
VRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKI
LKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRFLESHLDDAEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEK
PPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRM
TISRLVLEEDSQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKK

--------------------------------------------------------------
>26505_26505_8_EMP2-TERF2_EMP2_chr16_10637427_ENST00000536829_TERF2_chr16_69419389_ENST00000603068_length(transcript)=2906nt_BP=390nt
GGCCTGGGAGTCCTTGCAGGGTGGCCTGGGTGACTGCTCACCAGCCCGGCCCTCCCCAGGGTTCTGGGCCAGAGCCTCCCTGGCCGTTGG
AGCGGGAGCTGTGGGTGGAACACTTCTGAATTGGGAGATTGCCTCGGACCTCCAGACGCCGAACATCTCAGCACATCCCGCTCTGGGCTT
TAAACGTGACCCCTCGCCTCGACTCGCCCTGCCCTGTGAAAATGTTGGTGCTTCTTGCTTTCATCATCGCCTTCCACATCACCTCTGCAG
CCTTGCTGTTCATTGCCACCGTCGACAATGCCTGGTGGGTAGGAGATGAGTTTTTTGCAGATGTCTGGAGAATATGTACCAACAACACGA
ATTGCACAGTCATCAATGACAGCTTTCAAGCTTTGCTTGTCAGGCCCTTGGGGAAGGAGCACACCGTGTCCCGATTGCTGCGGGTTATGC
AGTGTCTGTCGCGGATTGAAGAAGGGGAAAATTTAGACTGTTCCTTTGATATGGAGGCTGAGCTCACACCACTGGAATCAGCTATCAATG
TGCTGGAGATGATTAAAACGGAATTTACACTGACAGAAGCAGTGGTCGAATCCAGTAGAAAACTGGTCAAGGAAGCTGCTGTCATTATTT
GTATCAAAAACAAAGAATTTGAAAAGGCTTCAAAAATTTTGAAAAAACATATGTCCAAGGACCCCACAACTCAGAAGCTGAGAAATGATC
TCCTGAATATTATTCGAGAAAAGAACTTGGCCCATCCTGTTATCCAGAACTTTTCATATGAGACCTTCCAGCAGAAGATGCTGCGCTTCC
TGGAGAGCCACCTGGATGACGCCGAGCCCTACCTCCTCACGATGGCCAAAAAGGCTTTGAAATCTGAGTCCGCTGCCTCAAGTACAGGGA
AGGAAGATAAACAGCCAGCACCAGGGCCTGTGGAAAAGCCACCCAGAGAACCCGCAAGGCAGCTACGGAATCCTCCAACCACCATTGGAA
TGATGACTCTGAAAGCAGCTTTCAAGACTCTGTCTGGTGCACAGGATTCTGAGGCAGCCTTTGCAAAACTGGACCAGAAGGATCTGGTTC
TTCCTACTCAAGCTCTCCCAGCATCACCAGCCCTCAAAAACAAGAGACCCAGAAAAGATGAAAACGAAAGTTCAGCCCCGGCTGACGGTG
AGGGTGGCTCGGAACTGCAGCCCAAGAACAAGCGCATGACAATAAGCAGATTGGTCTTGGAGGAGGACAGCCAGAGTACTGAGCCCAGCG
CAGGCCTCAACTCCTCCCAGGAGGCCGCTTCAGCGCCACCATCCAAGCCCACCGTTCTCAACCAACCCCTCCCTGGAGAGAAGAATCCCA
AAGTACCCAAAGGCAAGTGGAACAGCTCTAATGGGGTTGAAGAAAAGGAGACTTGGGTGGAAGAGGATGAACTGTTTCAAGTTCAGGCAG
CACCAGATGAAGACAGTACAACCAATATAACAAAAAAGCAGAAGTGGACTGTAGAAGAAAGCGAGTGGGTCAAGGCTGGAGTGCAGAAAT
ATGGGGAAGGAAACTGGGCTGCCATTTCTAAAAATTACCCATTTGTTAACCGAACAGCTGTGATGATTAAGGATCGCTGGCGGACCATGA
AAAGACTTGGCATGAACTGAAACAGGCTTTCATTTCCACAGAATTCACAGGAGCATGGTTCCTAATAATAGCCCCTGATAGTCTGCTCTT
TCTTTCTTTTTCTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCG
ACCTCCGTCTCCCGGGCTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCATCACGCCCGGCTAATGT
TTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCAACTCGGCCTCCCA
AAGTGCTGGGATTACAGGCATGAGCCACCGCGCCTGGCATCTGCTGTTTCTTTCAGAAGCTGGGCTGGGATGAGAATTTTGGGCAACCTC
CTTCGACGTGGGGGAGGTCCCATTTCCACTTCATCACTGTTGGAGATCATGGAGCTAAGAAGCAGAGCCAAGTCCACCCATGTCCTTGGC
AGAGATGACAGGCACACAGCTTGTGCAGTGCCAGAATATCATTAGCGTTTCCCTTCTTTAGTGGTTTGCTTAAATTTAAATCCCTGGTAA
TCTGTAGAACCTTCTCCTAGGAAATGGTGAAGTCTATTAGGAGCCACTTGTGACTCCATGACCTGTTAAAACCAGCAATGTGAGTATTAT
TTGGAGTAAATTTGTTCCACGTCAAGTTCTGGCCTTCTGATGCAAATGCAAAGGAACTTAGTCTGTTATGAACCCAGGTTGATGACAGAC
CAGTCCTTGTGGAATAAGATTCCCTTTAAAAACTCTTTAGCCAGTCGTGACATCAACCCTAGACCTGTCTGCCTTGGCATTTGCTGTCAA
CATCTGCTGGGCTATGTAGGCAGGTTAATCCTCCACTTCTCATGTGGTTGAACCAGTGTGTTTTTTGGTAAAATGGTGATTGTAGATAAG
ATTAGTTCCCTGATCCCCTGCCCCCTGTCCCCTGCCTCTTTTCCCAATTCCCTTCCTTATGCTGGACTTTTAAAGCTTAAAAAAAATCCG
ATTGAATATAAATGCCTAATTTCATTCTTTGTGAAATGGTTGCTTCCTCCTGATTCCCTAATTGTGCTGTGTTCGTGTCTTGCACTGGAA
TTCAACATTCCCTTCTCCTTTTGTACTGTGTTGTGCTTGCTGTCTCTCCCGGACACCCTTAAAGACTGTCTTTTTAGCAAAAAATTTCAG

>26505_26505_8_EMP2-TERF2_EMP2_chr16_10637427_ENST00000536829_TERF2_chr16_69419389_ENST00000603068_length(amino acids)=503AA_BP=87
MPRTSRRRTSQHIPLWALNVTPRLDSPCPVKMLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDSFQALL
VRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKI
LKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRFLESHLDDAEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEK
PPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRM
TISRLVLEEDSQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for EMP2-TERF2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EMP2-TERF2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for EMP2-TERF2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneEMP2C0403396Steroid-sensitive nephrotic syndrome1GENOMICS_ENGLAND
HgeneEMP2C1868672NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE1ORPHANET
HgeneEMP2C4014507NEPHROTIC SYNDROME, TYPE 101CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneC0023493Adult T-Cell Lymphoma/Leukemia1CTD_human