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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ABCA2-TRIM14 (FusionGDB2 ID:HG20TG9830)

Fusion Gene Summary for ABCA2-TRIM14

check button Fusion gene summary
Fusion gene informationFusion gene name: ABCA2-TRIM14
Fusion gene ID: hg20tg9830
HgeneTgene
Gene symbol

ABCA2

TRIM14

Gene ID

20

9830

Gene nameATP binding cassette subfamily A member 2tripartite motif containing 14
SynonymsABC2-
Cytomap('ABCA2')('TRIM14')

9q34.3

9q22.33

Type of geneprotein-codingprotein-coding
DescriptionATP-binding cassette sub-family A member 2ATP-binding cassette 2ATP-binding cassette transporter 2ATP-binding cassette, sub-family A (ABC1), member 2ATP-binding cassette, sub-family A, member 2tripartite motif-containing protein 14tripartite motif protein TRIM14
Modification date2020031320200315
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000265662, ENST00000341511, 
ENST00000371605, ENST00000492260, 
Fusion gene scores* DoF score9 X 10 X 3=2707 X 7 X 3=147
# samples 108
** MAII scorelog2(10/270*10)=-1.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(8/147*10)=-0.877744249949002
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ABCA2 [Title/Abstract] AND TRIM14 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointABCA2(139922527)-TRIM14(100862446), # samples:3
Anticipated loss of major functional domain due to fusion event.ABCA2-TRIM14 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABCA2-TRIM14 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABCA2-TRIM14 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ABCA2-TRIM14 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneABCA2

GO:0006357

regulation of transcription by RNA polymerase II

15238223

HgeneABCA2

GO:0010872

regulation of cholesterol esterification

24201375

HgeneABCA2

GO:0032384

negative regulation of intracellular cholesterol transport

21810484

HgeneABCA2

GO:0032805

positive regulation of low-density lipoprotein particle receptor catabolic process

21810484

HgeneABCA2

GO:0042986

positive regulation of amyloid precursor protein biosynthetic process

20704561

HgeneABCA2

GO:0045540

regulation of cholesterol biosynthetic process

21810484

HgeneABCA2

GO:0046512

sphingosine biosynthetic process

26510981

HgeneABCA2

GO:0071072

negative regulation of phospholipid biosynthetic process

24201375

HgeneABCA2

GO:0090155

negative regulation of sphingolipid biosynthetic process

24201375

HgeneABCA2

GO:0090156

cellular sphingolipid homeostasis

26510981

HgeneABCA2

GO:0090370

negative regulation of cholesterol efflux

21810484

HgeneABCA2

GO:0099040

ceramide translocation

24201375

HgeneABCA2

GO:1905598

negative regulation of low-density lipoprotein receptor activity

21810484

HgeneABCA2

GO:1905601

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

21810484

TgeneTRIM14

GO:0032897

negative regulation of viral transcription

18248090

TgeneTRIM14

GO:0045087

innate immune response

18248090

TgeneTRIM14

GO:0051091

positive regulation of DNA-binding transcription factor activity

23077300

TgeneTRIM14

GO:0051092

positive regulation of NF-kappaB transcription factor activity

23077300


check buttonFusion gene breakpoints across ABCA2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across TRIM14 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-E1-5304-01AABCA2chr9

139922527

-TRIM14chr9

100862446

-
ChimerDB4LGGTCGA-E1-5304ABCA2chr9

139922526

-TRIM14chr9

100862446

-
ChimerDB4LGGTCGA-E1-5304ABCA2chr9

139922527

-TRIM14chr9

100862446

-
ChimerDB4LGGTCGA-E1-5304ABCA2chr9

139923169

-TRIM14chr9

100862446

-


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Fusion Gene ORF analysis for ABCA2-TRIM14

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000265662ENST00000341469ABCA2chr9

139922527

-TRIM14chr9

100862446

-
5CDS-intronENST00000265662ENST00000341469ABCA2chr9

139922526

-TRIM14chr9

100862446

-
5CDS-intronENST00000265662ENST00000342043ABCA2chr9

139922527

-TRIM14chr9

100862446

-
5CDS-intronENST00000265662ENST00000342043ABCA2chr9

139922526

-TRIM14chr9

100862446

-
5CDS-intronENST00000265662ENST00000478530ABCA2chr9

139922527

-TRIM14chr9

100862446

-
5CDS-intronENST00000265662ENST00000478530ABCA2chr9

139922526

-TRIM14chr9

100862446

-
5CDS-intronENST00000265662ENST00000538344ABCA2chr9

139922527

-TRIM14chr9

100862446

-
5CDS-intronENST00000265662ENST00000538344ABCA2chr9

139922526

-TRIM14chr9

100862446

-
5CDS-intronENST00000341511ENST00000341469ABCA2chr9

139922527

-TRIM14chr9

100862446

-
5CDS-intronENST00000341511ENST00000341469ABCA2chr9

139922526

-TRIM14chr9

100862446

-
5CDS-intronENST00000341511ENST00000342043ABCA2chr9

139922527

-TRIM14chr9

100862446

-
5CDS-intronENST00000341511ENST00000342043ABCA2chr9

139922526

-TRIM14chr9

100862446

-
5CDS-intronENST00000341511ENST00000478530ABCA2chr9

139922527

-TRIM14chr9

100862446

-
5CDS-intronENST00000341511ENST00000478530ABCA2chr9

139922526

-TRIM14chr9

100862446

-
5CDS-intronENST00000341511ENST00000538344ABCA2chr9

139922527

-TRIM14chr9

100862446

-
5CDS-intronENST00000341511ENST00000538344ABCA2chr9

139922526

-TRIM14chr9

100862446

-
5CDS-intronENST00000371605ENST00000341469ABCA2chr9

139922527

-TRIM14chr9

100862446

-
5CDS-intronENST00000371605ENST00000341469ABCA2chr9

139922526

-TRIM14chr9

100862446

-
5CDS-intronENST00000371605ENST00000342043ABCA2chr9

139922527

-TRIM14chr9

100862446

-
5CDS-intronENST00000371605ENST00000342043ABCA2chr9

139922526

-TRIM14chr9

100862446

-
5CDS-intronENST00000371605ENST00000478530ABCA2chr9

139922527

-TRIM14chr9

100862446

-
5CDS-intronENST00000371605ENST00000478530ABCA2chr9

139922526

-TRIM14chr9

100862446

-
5CDS-intronENST00000371605ENST00000538344ABCA2chr9

139922527

-TRIM14chr9

100862446

-
5CDS-intronENST00000371605ENST00000538344ABCA2chr9

139922526

-TRIM14chr9

100862446

-
5UTR-3CDSENST00000492260ENST00000375098ABCA2chr9

139922527

-TRIM14chr9

100862446

-
5UTR-3CDSENST00000492260ENST00000375098ABCA2chr9

139922526

-TRIM14chr9

100862446

-
5UTR-intronENST00000492260ENST00000341469ABCA2chr9

139922527

-TRIM14chr9

100862446

-
5UTR-intronENST00000492260ENST00000341469ABCA2chr9

139922526

-TRIM14chr9

100862446

-
5UTR-intronENST00000492260ENST00000342043ABCA2chr9

139922527

-TRIM14chr9

100862446

-
5UTR-intronENST00000492260ENST00000342043ABCA2chr9

139922526

-TRIM14chr9

100862446

-
5UTR-intronENST00000492260ENST00000478530ABCA2chr9

139922527

-TRIM14chr9

100862446

-
5UTR-intronENST00000492260ENST00000478530ABCA2chr9

139922526

-TRIM14chr9

100862446

-
5UTR-intronENST00000492260ENST00000538344ABCA2chr9

139922527

-TRIM14chr9

100862446

-
5UTR-intronENST00000492260ENST00000538344ABCA2chr9

139922526

-TRIM14chr9

100862446

-
In-frameENST00000265662ENST00000375098ABCA2chr9

139922527

-TRIM14chr9

100862446

-
In-frameENST00000265662ENST00000375098ABCA2chr9

139922526

-TRIM14chr9

100862446

-
In-frameENST00000341511ENST00000375098ABCA2chr9

139922527

-TRIM14chr9

100862446

-
In-frameENST00000341511ENST00000375098ABCA2chr9

139922526

-TRIM14chr9

100862446

-
In-frameENST00000371605ENST00000375098ABCA2chr9

139922527

-TRIM14chr9

100862446

-
In-frameENST00000371605ENST00000375098ABCA2chr9

139922526

-TRIM14chr9

100862446

-
intron-3CDSENST00000265662ENST00000375098ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-3CDSENST00000341511ENST00000375098ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-3CDSENST00000371605ENST00000375098ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-3CDSENST00000492260ENST00000375098ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-intronENST00000265662ENST00000341469ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-intronENST00000265662ENST00000342043ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-intronENST00000265662ENST00000478530ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-intronENST00000265662ENST00000538344ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-intronENST00000341511ENST00000341469ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-intronENST00000341511ENST00000342043ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-intronENST00000341511ENST00000478530ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-intronENST00000341511ENST00000538344ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-intronENST00000371605ENST00000341469ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-intronENST00000371605ENST00000342043ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-intronENST00000371605ENST00000478530ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-intronENST00000371605ENST00000538344ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-intronENST00000492260ENST00000341469ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-intronENST00000492260ENST00000342043ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-intronENST00000492260ENST00000478530ABCA2chr9

139923169

-TRIM14chr9

100862446

-
intron-intronENST00000492260ENST00000538344ABCA2chr9

139923169

-TRIM14chr9

100862446

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000341511ABCA2chr9139922527-ENST00000375098TRIM14chr9100862446-1583116501141363
ENST00000265662ABCA2chr9139922527-ENST00000375098TRIM14chr9100862446-16812141481239363
ENST00000371605ABCA2chr9139922527-ENST00000375098TRIM14chr9100862446-16812141481239363
ENST00000341511ABCA2chr9139922526-ENST00000375098TRIM14chr9100862446-1583116501141363
ENST00000265662ABCA2chr9139922526-ENST00000375098TRIM14chr9100862446-16812141481239363
ENST00000371605ABCA2chr9139922526-ENST00000375098TRIM14chr9100862446-16812141481239363

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000341511ENST00000375098ABCA2chr9139922527-TRIM14chr9100862446-0.0251190810.974881
ENST00000265662ENST00000375098ABCA2chr9139922527-TRIM14chr9100862446-0.0246457010.9753543
ENST00000371605ENST00000375098ABCA2chr9139922527-TRIM14chr9100862446-0.0246457010.9753543
ENST00000341511ENST00000375098ABCA2chr9139922526-TRIM14chr9100862446-0.0251190810.974881
ENST00000265662ENST00000375098ABCA2chr9139922526-TRIM14chr9100862446-0.0246457010.9753543
ENST00000371605ENST00000375098ABCA2chr9139922526-TRIM14chr9100862446-0.0246457010.9753543

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Fusion Genomic Features for ABCA2-TRIM14


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ABCA2-TRIM14


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:139922527/chr9:100862446)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTRIM14chr9:139922526chr9:100862446ENST0000034146916135_156101443.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM14chr9:139922526chr9:100862446ENST0000034204317135_156101564.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM14chr9:139922526chr9:100862446ENST0000037509817135_156101660.3333333333334Coiled coilOntology_term=ECO:0000255
TgeneTRIM14chr9:139922527chr9:100862446ENST0000034146916135_156101443.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM14chr9:139922527chr9:100862446ENST0000034204317135_156101564.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM14chr9:139922527chr9:100862446ENST0000037509817135_156101660.3333333333334Coiled coilOntology_term=ECO:0000255
TgeneTRIM14chr9:139922526chr9:100862446ENST0000034146916249_442101443.0DomainB30.2/SPRY
TgeneTRIM14chr9:139922526chr9:100862446ENST0000034204317249_442101564.0DomainB30.2/SPRY
TgeneTRIM14chr9:139922526chr9:100862446ENST0000037509817249_442101660.3333333333334DomainB30.2/SPRY
TgeneTRIM14chr9:139922527chr9:100862446ENST0000034146916249_442101443.0DomainB30.2/SPRY
TgeneTRIM14chr9:139922527chr9:100862446ENST0000034204317249_442101564.0DomainB30.2/SPRY
TgeneTRIM14chr9:139922527chr9:100862446ENST0000037509817249_442101660.3333333333334DomainB30.2/SPRY

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-1492050_2285222437.0DomainABC transporter 2
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-149990_1221222437.0DomainABC transporter 1
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-1482050_2285222436.0DomainABC transporter 2
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-148990_1221222436.0DomainABC transporter 1
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-1492050_2285222437.0DomainABC transporter 2
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-149990_1221222437.0DomainABC transporter 1
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-1482050_2285222436.0DomainABC transporter 2
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-148990_1221222436.0DomainABC transporter 1
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-1491024_1031222437.0Nucleotide bindingATP 1
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-1492087_2094222437.0Nucleotide bindingATP 2
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-1481024_1031222436.0Nucleotide bindingATP 1
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-1482087_2094222436.0Nucleotide bindingATP 2
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-1491024_1031222437.0Nucleotide bindingATP 1
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-1492087_2094222437.0Nucleotide bindingATP 2
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-1481024_1031222436.0Nucleotide bindingATP 1
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-1482087_2094222436.0Nucleotide bindingATP 2
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-1491456_1476222437.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-1491792_1812222437.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-1491841_1861222437.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-1491872_1892222437.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-1491905_1925222437.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-1491991_2011222437.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-14922_42222437.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-14954_74222437.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-149699_719222437.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-149750_770222437.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-149782_802222437.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-149813_833222437.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-149857_877222437.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000341511-149893_913222437.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-1481456_1476222436.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-1481792_1812222436.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-1481841_1861222436.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-1481872_1892222436.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-1481905_1925222436.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-1481991_2011222436.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-14822_42222436.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-14854_74222436.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-148699_719222436.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-148750_770222436.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-148782_802222436.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-148813_833222436.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-148857_877222436.0TransmembraneHelical
HgeneABCA2chr9:139922526chr9:100862446ENST00000371605-148893_913222436.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-1491456_1476222437.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-1491792_1812222437.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-1491841_1861222437.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-1491872_1892222437.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-1491905_1925222437.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-1491991_2011222437.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-14922_42222437.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-14954_74222437.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-149699_719222437.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-149750_770222437.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-149782_802222437.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-149813_833222437.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-149857_877222437.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000341511-149893_913222437.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-1481456_1476222436.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-1481792_1812222436.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-1481841_1861222436.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-1481872_1892222436.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-1481905_1925222436.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-1481991_2011222436.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-14822_42222436.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-14854_74222436.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-148699_719222436.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-148750_770222436.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-148782_802222436.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-148813_833222436.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-148857_877222436.0TransmembraneHelical
HgeneABCA2chr9:139922527chr9:100862446ENST00000371605-148893_913222436.0TransmembraneHelical
TgeneTRIM14chr9:139922526chr9:100862446ENST000003414691676_109101443.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM14chr9:139922526chr9:100862446ENST000003420431776_109101564.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM14chr9:139922526chr9:100862446ENST000003750981776_109101660.3333333333334Coiled coilOntology_term=ECO:0000255
TgeneTRIM14chr9:139922527chr9:100862446ENST000003414691676_109101443.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM14chr9:139922527chr9:100862446ENST000003420431776_109101564.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM14chr9:139922527chr9:100862446ENST000003750981776_109101660.3333333333334Coiled coilOntology_term=ECO:0000255
TgeneTRIM14chr9:139922526chr9:100862446ENST000003414691619_61101443.0Zinc fingerB box-type
TgeneTRIM14chr9:139922526chr9:100862446ENST000003420431719_61101564.0Zinc fingerB box-type
TgeneTRIM14chr9:139922526chr9:100862446ENST000003750981719_61101660.3333333333334Zinc fingerB box-type
TgeneTRIM14chr9:139922527chr9:100862446ENST000003414691619_61101443.0Zinc fingerB box-type
TgeneTRIM14chr9:139922527chr9:100862446ENST000003420431719_61101564.0Zinc fingerB box-type
TgeneTRIM14chr9:139922527chr9:100862446ENST000003750981719_61101660.3333333333334Zinc fingerB box-type


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Fusion Gene Sequence for ABCA2-TRIM14


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>185_185_1_ABCA2-TRIM14_ABCA2_chr9_139922526_ENST00000265662_TRIM14_chr9_100862446_ENST00000375098_length(transcript)=1681nt_BP=214nt
GGGGCGGAGCCAGCGCGGATCGGGTCCCGGACGCCCGAGCGCCCCGCCCCCGCGCGGGCGATGCCCAGCGGCGCGGCGGGCTGCGGGGCC
CGGCGGGGCGCGCAGAGGAGCGGGCCGCGGCGCTGAGGCGGCGGAGCGTGGCCCCGCCATGGGCTTCCTGCACCAGCTGCAGCTGCTGCT
CTGGAAGAACGTGACGCTCAAACGCCGGAGCCCGGCTAATGCAGAGTCAAGTAAAACCTGGCTGAAGGGGAAATTCACTGAACTCAGATT
ACTACTTGACGAAGAGGAAGCGCTGGCCAAGAAATTCATTGATAAAAACACGCAGCTTACCCTCCAGGTGTACAGGGAACAAGCTGACTC
TTGCAGAGAGCAACTTGACATCATGAATGATCTCTCCAACAGGGTCTGGAGTATCAGCCAGGAGCCCGATCCTGTCCAGAGGCTTCAGGC
ATACACGGCCACCGAGCAGGAGATGCAGCAGCAGATGAGCCTCGGGGAGCTGTGCCATCCCGTGCCCCTCTCCTTTGAGCCCGTCAAGAG
CTTCTTTAAGGGCCTCGTGGAAGCCGTGGAGAGTACATTACAGACGCCATTGGACATTCGCCTTAAGGAAAGCATAAACTGCCAGCTCTC
AGACCCTTCCAGCACCAAGCCAGGTACCTTGTTGAAAACCAGCCCCTCACCAGAGCGATCGCTATTGCTGAAATACGCGCGCACGCCCAC
GCTGGATCCTGACACGATGCACGCGCGCCTGCGCCTGTCCGCCGATCGCCTGACGGTGCGCTGCGGCCTGCTGGGCAGCCTGGGGCCCGT
GCCCGTGCTGCGGTTCGACGCGCTCTGGCAAGTGCTGGCTCGTGACTGCTTCGCCACCGGCCGCCACTACTGGGAGGTTGACGTGCAGGA
GGCGGGCGCCGGCTGGTGGGTGGGCGCGGCCTACGCCTCCCTTCGGCGCCGCGGGGCCTCGGCCGCCGCCCGCCTGGGCTGCAACCGCCA
GTCCTGGTGCCTCAAGCGCTACGACCTTGAGTACTGGGCCTTCCACGACGGCCAGCGCAGCCGCCTGCGGCCCCGCGACGACCTCGACCG
GCTCGGCGTCTTCCTGGACTACGAGGCCGGCGTCCTCGCCTTCTACGACGTGACGGGCGGCATGAGCCACCTGCATACCTTCCGCGCCAC
GTTCCAGGAGCCGCTCTACCCGGCCCTGCGGCTCTGGGAGGGGGCCATCAGCATCCCCCGGCTGCCCTAGGGGCCAGGACCGGCGTGACA
GCCTCCAGAATGTCATGGAAGCAGAATCGTACAGTATGTTCCCTTCTGCATATGCTGCTTTCTCACTCAGCATCATTTCCTTGAGATGCA
TCCAGGCTGCTGCACGCATCAATAGTTCATTCCTGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCGCTTTGGGAGGCCGATGTGGG
TGGATCACAAGGTCAGGAGTTTGAGACTAGCCTGGCCAAGATGGTGAAACCCCATCTCTGCAAAAAATACAAAAATTAGCCGGGCACCAT
GGCATGTGCCTGTAATCCCTGCTACTCAGGAGGCTGAGGAAGGAGAATCACTTGAACCCGGGCAGCGGAGGTTGCAGTGAGCCGAGATCA

>185_185_1_ABCA2-TRIM14_ABCA2_chr9_139922526_ENST00000265662_TRIM14_chr9_100862446_ENST00000375098_length(amino acids)=363AA_BP=22
MGFLHQLQLLLWKNVTLKRRSPANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSIS
QEPDPVQRLQAYTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSPER
SLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGA
SAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGAISIP

--------------------------------------------------------------
>185_185_2_ABCA2-TRIM14_ABCA2_chr9_139922526_ENST00000341511_TRIM14_chr9_100862446_ENST00000375098_length(transcript)=1583nt_BP=116nt
CGCGCAGAGGAGCGGGCCGCGGCGCTGAGGCGGCGGAGCGTGGCCCCGCCATGGGCTTCCTGCACCAGCTGCAGCTGCTGCTCTGGAAGA
ACGTGACGCTCAAACGCCGGAGCCCGGCTAATGCAGAGTCAAGTAAAACCTGGCTGAAGGGGAAATTCACTGAACTCAGATTACTACTTG
ACGAAGAGGAAGCGCTGGCCAAGAAATTCATTGATAAAAACACGCAGCTTACCCTCCAGGTGTACAGGGAACAAGCTGACTCTTGCAGAG
AGCAACTTGACATCATGAATGATCTCTCCAACAGGGTCTGGAGTATCAGCCAGGAGCCCGATCCTGTCCAGAGGCTTCAGGCATACACGG
CCACCGAGCAGGAGATGCAGCAGCAGATGAGCCTCGGGGAGCTGTGCCATCCCGTGCCCCTCTCCTTTGAGCCCGTCAAGAGCTTCTTTA
AGGGCCTCGTGGAAGCCGTGGAGAGTACATTACAGACGCCATTGGACATTCGCCTTAAGGAAAGCATAAACTGCCAGCTCTCAGACCCTT
CCAGCACCAAGCCAGGTACCTTGTTGAAAACCAGCCCCTCACCAGAGCGATCGCTATTGCTGAAATACGCGCGCACGCCCACGCTGGATC
CTGACACGATGCACGCGCGCCTGCGCCTGTCCGCCGATCGCCTGACGGTGCGCTGCGGCCTGCTGGGCAGCCTGGGGCCCGTGCCCGTGC
TGCGGTTCGACGCGCTCTGGCAAGTGCTGGCTCGTGACTGCTTCGCCACCGGCCGCCACTACTGGGAGGTTGACGTGCAGGAGGCGGGCG
CCGGCTGGTGGGTGGGCGCGGCCTACGCCTCCCTTCGGCGCCGCGGGGCCTCGGCCGCCGCCCGCCTGGGCTGCAACCGCCAGTCCTGGT
GCCTCAAGCGCTACGACCTTGAGTACTGGGCCTTCCACGACGGCCAGCGCAGCCGCCTGCGGCCCCGCGACGACCTCGACCGGCTCGGCG
TCTTCCTGGACTACGAGGCCGGCGTCCTCGCCTTCTACGACGTGACGGGCGGCATGAGCCACCTGCATACCTTCCGCGCCACGTTCCAGG
AGCCGCTCTACCCGGCCCTGCGGCTCTGGGAGGGGGCCATCAGCATCCCCCGGCTGCCCTAGGGGCCAGGACCGGCGTGACAGCCTCCAG
AATGTCATGGAAGCAGAATCGTACAGTATGTTCCCTTCTGCATATGCTGCTTTCTCACTCAGCATCATTTCCTTGAGATGCATCCAGGCT
GCTGCACGCATCAATAGTTCATTCCTGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCGCTTTGGGAGGCCGATGTGGGTGGATCAC
AAGGTCAGGAGTTTGAGACTAGCCTGGCCAAGATGGTGAAACCCCATCTCTGCAAAAAATACAAAAATTAGCCGGGCACCATGGCATGTG
CCTGTAATCCCTGCTACTCAGGAGGCTGAGGAAGGAGAATCACTTGAACCCGGGCAGCGGAGGTTGCAGTGAGCCGAGATCACACCACTG

>185_185_2_ABCA2-TRIM14_ABCA2_chr9_139922526_ENST00000341511_TRIM14_chr9_100862446_ENST00000375098_length(amino acids)=363AA_BP=22
MGFLHQLQLLLWKNVTLKRRSPANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSIS
QEPDPVQRLQAYTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSPER
SLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGA
SAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGAISIP

--------------------------------------------------------------
>185_185_3_ABCA2-TRIM14_ABCA2_chr9_139922526_ENST00000371605_TRIM14_chr9_100862446_ENST00000375098_length(transcript)=1681nt_BP=214nt
GGGGCGGAGCCAGCGCGGATCGGGTCCCGGACGCCCGAGCGCCCCGCCCCCGCGCGGGCGATGCCCAGCGGCGCGGCGGGCTGCGGGGCC
CGGCGGGGCGCGCAGAGGAGCGGGCCGCGGCGCTGAGGCGGCGGAGCGTGGCCCCGCCATGGGCTTCCTGCACCAGCTGCAGCTGCTGCT
CTGGAAGAACGTGACGCTCAAACGCCGGAGCCCGGCTAATGCAGAGTCAAGTAAAACCTGGCTGAAGGGGAAATTCACTGAACTCAGATT
ACTACTTGACGAAGAGGAAGCGCTGGCCAAGAAATTCATTGATAAAAACACGCAGCTTACCCTCCAGGTGTACAGGGAACAAGCTGACTC
TTGCAGAGAGCAACTTGACATCATGAATGATCTCTCCAACAGGGTCTGGAGTATCAGCCAGGAGCCCGATCCTGTCCAGAGGCTTCAGGC
ATACACGGCCACCGAGCAGGAGATGCAGCAGCAGATGAGCCTCGGGGAGCTGTGCCATCCCGTGCCCCTCTCCTTTGAGCCCGTCAAGAG
CTTCTTTAAGGGCCTCGTGGAAGCCGTGGAGAGTACATTACAGACGCCATTGGACATTCGCCTTAAGGAAAGCATAAACTGCCAGCTCTC
AGACCCTTCCAGCACCAAGCCAGGTACCTTGTTGAAAACCAGCCCCTCACCAGAGCGATCGCTATTGCTGAAATACGCGCGCACGCCCAC
GCTGGATCCTGACACGATGCACGCGCGCCTGCGCCTGTCCGCCGATCGCCTGACGGTGCGCTGCGGCCTGCTGGGCAGCCTGGGGCCCGT
GCCCGTGCTGCGGTTCGACGCGCTCTGGCAAGTGCTGGCTCGTGACTGCTTCGCCACCGGCCGCCACTACTGGGAGGTTGACGTGCAGGA
GGCGGGCGCCGGCTGGTGGGTGGGCGCGGCCTACGCCTCCCTTCGGCGCCGCGGGGCCTCGGCCGCCGCCCGCCTGGGCTGCAACCGCCA
GTCCTGGTGCCTCAAGCGCTACGACCTTGAGTACTGGGCCTTCCACGACGGCCAGCGCAGCCGCCTGCGGCCCCGCGACGACCTCGACCG
GCTCGGCGTCTTCCTGGACTACGAGGCCGGCGTCCTCGCCTTCTACGACGTGACGGGCGGCATGAGCCACCTGCATACCTTCCGCGCCAC
GTTCCAGGAGCCGCTCTACCCGGCCCTGCGGCTCTGGGAGGGGGCCATCAGCATCCCCCGGCTGCCCTAGGGGCCAGGACCGGCGTGACA
GCCTCCAGAATGTCATGGAAGCAGAATCGTACAGTATGTTCCCTTCTGCATATGCTGCTTTCTCACTCAGCATCATTTCCTTGAGATGCA
TCCAGGCTGCTGCACGCATCAATAGTTCATTCCTGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCGCTTTGGGAGGCCGATGTGGG
TGGATCACAAGGTCAGGAGTTTGAGACTAGCCTGGCCAAGATGGTGAAACCCCATCTCTGCAAAAAATACAAAAATTAGCCGGGCACCAT
GGCATGTGCCTGTAATCCCTGCTACTCAGGAGGCTGAGGAAGGAGAATCACTTGAACCCGGGCAGCGGAGGTTGCAGTGAGCCGAGATCA

>185_185_3_ABCA2-TRIM14_ABCA2_chr9_139922526_ENST00000371605_TRIM14_chr9_100862446_ENST00000375098_length(amino acids)=363AA_BP=22
MGFLHQLQLLLWKNVTLKRRSPANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSIS
QEPDPVQRLQAYTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSPER
SLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGA
SAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGAISIP

--------------------------------------------------------------
>185_185_4_ABCA2-TRIM14_ABCA2_chr9_139922527_ENST00000265662_TRIM14_chr9_100862446_ENST00000375098_length(transcript)=1681nt_BP=214nt
GGGGCGGAGCCAGCGCGGATCGGGTCCCGGACGCCCGAGCGCCCCGCCCCCGCGCGGGCGATGCCCAGCGGCGCGGCGGGCTGCGGGGCC
CGGCGGGGCGCGCAGAGGAGCGGGCCGCGGCGCTGAGGCGGCGGAGCGTGGCCCCGCCATGGGCTTCCTGCACCAGCTGCAGCTGCTGCT
CTGGAAGAACGTGACGCTCAAACGCCGGAGCCCGGCTAATGCAGAGTCAAGTAAAACCTGGCTGAAGGGGAAATTCACTGAACTCAGATT
ACTACTTGACGAAGAGGAAGCGCTGGCCAAGAAATTCATTGATAAAAACACGCAGCTTACCCTCCAGGTGTACAGGGAACAAGCTGACTC
TTGCAGAGAGCAACTTGACATCATGAATGATCTCTCCAACAGGGTCTGGAGTATCAGCCAGGAGCCCGATCCTGTCCAGAGGCTTCAGGC
ATACACGGCCACCGAGCAGGAGATGCAGCAGCAGATGAGCCTCGGGGAGCTGTGCCATCCCGTGCCCCTCTCCTTTGAGCCCGTCAAGAG
CTTCTTTAAGGGCCTCGTGGAAGCCGTGGAGAGTACATTACAGACGCCATTGGACATTCGCCTTAAGGAAAGCATAAACTGCCAGCTCTC
AGACCCTTCCAGCACCAAGCCAGGTACCTTGTTGAAAACCAGCCCCTCACCAGAGCGATCGCTATTGCTGAAATACGCGCGCACGCCCAC
GCTGGATCCTGACACGATGCACGCGCGCCTGCGCCTGTCCGCCGATCGCCTGACGGTGCGCTGCGGCCTGCTGGGCAGCCTGGGGCCCGT
GCCCGTGCTGCGGTTCGACGCGCTCTGGCAAGTGCTGGCTCGTGACTGCTTCGCCACCGGCCGCCACTACTGGGAGGTTGACGTGCAGGA
GGCGGGCGCCGGCTGGTGGGTGGGCGCGGCCTACGCCTCCCTTCGGCGCCGCGGGGCCTCGGCCGCCGCCCGCCTGGGCTGCAACCGCCA
GTCCTGGTGCCTCAAGCGCTACGACCTTGAGTACTGGGCCTTCCACGACGGCCAGCGCAGCCGCCTGCGGCCCCGCGACGACCTCGACCG
GCTCGGCGTCTTCCTGGACTACGAGGCCGGCGTCCTCGCCTTCTACGACGTGACGGGCGGCATGAGCCACCTGCATACCTTCCGCGCCAC
GTTCCAGGAGCCGCTCTACCCGGCCCTGCGGCTCTGGGAGGGGGCCATCAGCATCCCCCGGCTGCCCTAGGGGCCAGGACCGGCGTGACA
GCCTCCAGAATGTCATGGAAGCAGAATCGTACAGTATGTTCCCTTCTGCATATGCTGCTTTCTCACTCAGCATCATTTCCTTGAGATGCA
TCCAGGCTGCTGCACGCATCAATAGTTCATTCCTGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCGCTTTGGGAGGCCGATGTGGG
TGGATCACAAGGTCAGGAGTTTGAGACTAGCCTGGCCAAGATGGTGAAACCCCATCTCTGCAAAAAATACAAAAATTAGCCGGGCACCAT
GGCATGTGCCTGTAATCCCTGCTACTCAGGAGGCTGAGGAAGGAGAATCACTTGAACCCGGGCAGCGGAGGTTGCAGTGAGCCGAGATCA

>185_185_4_ABCA2-TRIM14_ABCA2_chr9_139922527_ENST00000265662_TRIM14_chr9_100862446_ENST00000375098_length(amino acids)=363AA_BP=22
MGFLHQLQLLLWKNVTLKRRSPANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSIS
QEPDPVQRLQAYTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSPER
SLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGA
SAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGAISIP

--------------------------------------------------------------
>185_185_5_ABCA2-TRIM14_ABCA2_chr9_139922527_ENST00000341511_TRIM14_chr9_100862446_ENST00000375098_length(transcript)=1583nt_BP=116nt
CGCGCAGAGGAGCGGGCCGCGGCGCTGAGGCGGCGGAGCGTGGCCCCGCCATGGGCTTCCTGCACCAGCTGCAGCTGCTGCTCTGGAAGA
ACGTGACGCTCAAACGCCGGAGCCCGGCTAATGCAGAGTCAAGTAAAACCTGGCTGAAGGGGAAATTCACTGAACTCAGATTACTACTTG
ACGAAGAGGAAGCGCTGGCCAAGAAATTCATTGATAAAAACACGCAGCTTACCCTCCAGGTGTACAGGGAACAAGCTGACTCTTGCAGAG
AGCAACTTGACATCATGAATGATCTCTCCAACAGGGTCTGGAGTATCAGCCAGGAGCCCGATCCTGTCCAGAGGCTTCAGGCATACACGG
CCACCGAGCAGGAGATGCAGCAGCAGATGAGCCTCGGGGAGCTGTGCCATCCCGTGCCCCTCTCCTTTGAGCCCGTCAAGAGCTTCTTTA
AGGGCCTCGTGGAAGCCGTGGAGAGTACATTACAGACGCCATTGGACATTCGCCTTAAGGAAAGCATAAACTGCCAGCTCTCAGACCCTT
CCAGCACCAAGCCAGGTACCTTGTTGAAAACCAGCCCCTCACCAGAGCGATCGCTATTGCTGAAATACGCGCGCACGCCCACGCTGGATC
CTGACACGATGCACGCGCGCCTGCGCCTGTCCGCCGATCGCCTGACGGTGCGCTGCGGCCTGCTGGGCAGCCTGGGGCCCGTGCCCGTGC
TGCGGTTCGACGCGCTCTGGCAAGTGCTGGCTCGTGACTGCTTCGCCACCGGCCGCCACTACTGGGAGGTTGACGTGCAGGAGGCGGGCG
CCGGCTGGTGGGTGGGCGCGGCCTACGCCTCCCTTCGGCGCCGCGGGGCCTCGGCCGCCGCCCGCCTGGGCTGCAACCGCCAGTCCTGGT
GCCTCAAGCGCTACGACCTTGAGTACTGGGCCTTCCACGACGGCCAGCGCAGCCGCCTGCGGCCCCGCGACGACCTCGACCGGCTCGGCG
TCTTCCTGGACTACGAGGCCGGCGTCCTCGCCTTCTACGACGTGACGGGCGGCATGAGCCACCTGCATACCTTCCGCGCCACGTTCCAGG
AGCCGCTCTACCCGGCCCTGCGGCTCTGGGAGGGGGCCATCAGCATCCCCCGGCTGCCCTAGGGGCCAGGACCGGCGTGACAGCCTCCAG
AATGTCATGGAAGCAGAATCGTACAGTATGTTCCCTTCTGCATATGCTGCTTTCTCACTCAGCATCATTTCCTTGAGATGCATCCAGGCT
GCTGCACGCATCAATAGTTCATTCCTGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCGCTTTGGGAGGCCGATGTGGGTGGATCAC
AAGGTCAGGAGTTTGAGACTAGCCTGGCCAAGATGGTGAAACCCCATCTCTGCAAAAAATACAAAAATTAGCCGGGCACCATGGCATGTG
CCTGTAATCCCTGCTACTCAGGAGGCTGAGGAAGGAGAATCACTTGAACCCGGGCAGCGGAGGTTGCAGTGAGCCGAGATCACACCACTG

>185_185_5_ABCA2-TRIM14_ABCA2_chr9_139922527_ENST00000341511_TRIM14_chr9_100862446_ENST00000375098_length(amino acids)=363AA_BP=22
MGFLHQLQLLLWKNVTLKRRSPANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSIS
QEPDPVQRLQAYTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSPER
SLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGA
SAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGAISIP

--------------------------------------------------------------
>185_185_6_ABCA2-TRIM14_ABCA2_chr9_139922527_ENST00000371605_TRIM14_chr9_100862446_ENST00000375098_length(transcript)=1681nt_BP=214nt
GGGGCGGAGCCAGCGCGGATCGGGTCCCGGACGCCCGAGCGCCCCGCCCCCGCGCGGGCGATGCCCAGCGGCGCGGCGGGCTGCGGGGCC
CGGCGGGGCGCGCAGAGGAGCGGGCCGCGGCGCTGAGGCGGCGGAGCGTGGCCCCGCCATGGGCTTCCTGCACCAGCTGCAGCTGCTGCT
CTGGAAGAACGTGACGCTCAAACGCCGGAGCCCGGCTAATGCAGAGTCAAGTAAAACCTGGCTGAAGGGGAAATTCACTGAACTCAGATT
ACTACTTGACGAAGAGGAAGCGCTGGCCAAGAAATTCATTGATAAAAACACGCAGCTTACCCTCCAGGTGTACAGGGAACAAGCTGACTC
TTGCAGAGAGCAACTTGACATCATGAATGATCTCTCCAACAGGGTCTGGAGTATCAGCCAGGAGCCCGATCCTGTCCAGAGGCTTCAGGC
ATACACGGCCACCGAGCAGGAGATGCAGCAGCAGATGAGCCTCGGGGAGCTGTGCCATCCCGTGCCCCTCTCCTTTGAGCCCGTCAAGAG
CTTCTTTAAGGGCCTCGTGGAAGCCGTGGAGAGTACATTACAGACGCCATTGGACATTCGCCTTAAGGAAAGCATAAACTGCCAGCTCTC
AGACCCTTCCAGCACCAAGCCAGGTACCTTGTTGAAAACCAGCCCCTCACCAGAGCGATCGCTATTGCTGAAATACGCGCGCACGCCCAC
GCTGGATCCTGACACGATGCACGCGCGCCTGCGCCTGTCCGCCGATCGCCTGACGGTGCGCTGCGGCCTGCTGGGCAGCCTGGGGCCCGT
GCCCGTGCTGCGGTTCGACGCGCTCTGGCAAGTGCTGGCTCGTGACTGCTTCGCCACCGGCCGCCACTACTGGGAGGTTGACGTGCAGGA
GGCGGGCGCCGGCTGGTGGGTGGGCGCGGCCTACGCCTCCCTTCGGCGCCGCGGGGCCTCGGCCGCCGCCCGCCTGGGCTGCAACCGCCA
GTCCTGGTGCCTCAAGCGCTACGACCTTGAGTACTGGGCCTTCCACGACGGCCAGCGCAGCCGCCTGCGGCCCCGCGACGACCTCGACCG
GCTCGGCGTCTTCCTGGACTACGAGGCCGGCGTCCTCGCCTTCTACGACGTGACGGGCGGCATGAGCCACCTGCATACCTTCCGCGCCAC
GTTCCAGGAGCCGCTCTACCCGGCCCTGCGGCTCTGGGAGGGGGCCATCAGCATCCCCCGGCTGCCCTAGGGGCCAGGACCGGCGTGACA
GCCTCCAGAATGTCATGGAAGCAGAATCGTACAGTATGTTCCCTTCTGCATATGCTGCTTTCTCACTCAGCATCATTTCCTTGAGATGCA
TCCAGGCTGCTGCACGCATCAATAGTTCATTCCTGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCGCTTTGGGAGGCCGATGTGGG
TGGATCACAAGGTCAGGAGTTTGAGACTAGCCTGGCCAAGATGGTGAAACCCCATCTCTGCAAAAAATACAAAAATTAGCCGGGCACCAT
GGCATGTGCCTGTAATCCCTGCTACTCAGGAGGCTGAGGAAGGAGAATCACTTGAACCCGGGCAGCGGAGGTTGCAGTGAGCCGAGATCA

>185_185_6_ABCA2-TRIM14_ABCA2_chr9_139922527_ENST00000371605_TRIM14_chr9_100862446_ENST00000375098_length(amino acids)=363AA_BP=22
MGFLHQLQLLLWKNVTLKRRSPANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSIS
QEPDPVQRLQAYTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSPER
SLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGA
SAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGAISIP

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Fusion Gene PPI Analysis for ABCA2-TRIM14


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ABCA2-TRIM14


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ABCA2-TRIM14


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource