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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EYA2-SYS1 (FusionGDB2 ID:HG2139TG90196)

Fusion Gene Summary for EYA2-SYS1

check button Fusion gene summary
Fusion gene informationFusion gene name: EYA2-SYS1
Fusion gene ID: hg2139tg90196
HgeneTgene
Gene symbol

EYA2

SYS1

Gene ID

2139

90196

Gene nameEYA transcriptional coactivator and phosphatase 2SYS1 golgi trafficking protein
SynonymsEAB1C20orf169|dJ453C12.4|dJ453C12.4.1
Cytomap('EYA2')('SYS1')

20q13.12

20q13.12

Type of geneprotein-codingprotein-coding
Descriptioneyes absent homolog 2protein SYS1 homologSYS1 Golgi-localized integral membrane protein homolog
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000317304, ENST00000327619, 
ENST00000357410, ENST00000497428, 
Fusion gene scores* DoF score7 X 5 X 6=2101 X 1 X 1=1
# samples 101
** MAII scorelog2(10/210*10)=-1.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(1/1*10)=3.32192809488736
Context

PubMed: EYA2 [Title/Abstract] AND SYS1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEYA2(45725807)-SYS1(43994259), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneEYA2

GO:0016576

histone dephosphorylation

19351884


check buttonFusion gene breakpoints across EYA2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across SYS1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-KK-A5A1-01AEYA2chr20

45725807

-SYS1chr20

43994259

+
ChimerDB4PRADTCGA-KK-A5A1-01AEYA2chr20

45725807

+SYS1chr20

43994259

+
ChimerDB4PRADTCGA-KK-A5A1EYA2chr20

45725807

+SYS1chr20

43994259

+


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Fusion Gene ORF analysis for EYA2-SYS1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000317304ENST00000479779EYA2chr20

45725807

+SYS1chr20

43994259

+
5CDS-3UTRENST00000327619ENST00000479779EYA2chr20

45725807

+SYS1chr20

43994259

+
5CDS-3UTRENST00000357410ENST00000479779EYA2chr20

45725807

+SYS1chr20

43994259

+
In-frameENST00000317304ENST00000243918EYA2chr20

45725807

+SYS1chr20

43994259

+
In-frameENST00000317304ENST00000372727EYA2chr20

45725807

+SYS1chr20

43994259

+
In-frameENST00000317304ENST00000414310EYA2chr20

45725807

+SYS1chr20

43994259

+
In-frameENST00000317304ENST00000426004EYA2chr20

45725807

+SYS1chr20

43994259

+
In-frameENST00000327619ENST00000243918EYA2chr20

45725807

+SYS1chr20

43994259

+
In-frameENST00000327619ENST00000372727EYA2chr20

45725807

+SYS1chr20

43994259

+
In-frameENST00000327619ENST00000414310EYA2chr20

45725807

+SYS1chr20

43994259

+
In-frameENST00000327619ENST00000426004EYA2chr20

45725807

+SYS1chr20

43994259

+
In-frameENST00000357410ENST00000243918EYA2chr20

45725807

+SYS1chr20

43994259

+
In-frameENST00000357410ENST00000372727EYA2chr20

45725807

+SYS1chr20

43994259

+
In-frameENST00000357410ENST00000414310EYA2chr20

45725807

+SYS1chr20

43994259

+
In-frameENST00000357410ENST00000426004EYA2chr20

45725807

+SYS1chr20

43994259

+
intron-3CDSENST00000497428ENST00000243918EYA2chr20

45725807

+SYS1chr20

43994259

+
intron-3CDSENST00000497428ENST00000372727EYA2chr20

45725807

+SYS1chr20

43994259

+
intron-3CDSENST00000497428ENST00000414310EYA2chr20

45725807

+SYS1chr20

43994259

+
intron-3CDSENST00000497428ENST00000426004EYA2chr20

45725807

+SYS1chr20

43994259

+
intron-3UTRENST00000497428ENST00000479779EYA2chr20

45725807

+SYS1chr20

43994259

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000357410EYA2chr2045725807+ENST00000372727SYS1chr2043994259+16701262681570500
ENST00000357410EYA2chr2045725807+ENST00000414310SYS1chr2043994259+16811262681570500
ENST00000357410EYA2chr2045725807+ENST00000243918SYS1chr2043994259+36711262681570500
ENST00000357410EYA2chr2045725807+ENST00000426004SYS1chr2043994259+38351262681330420
ENST00000327619EYA2chr2045725807+ENST00000372727SYS1chr2043994259+16701262681570500
ENST00000327619EYA2chr2045725807+ENST00000414310SYS1chr2043994259+16811262681570500
ENST00000327619EYA2chr2045725807+ENST00000243918SYS1chr2043994259+36711262681570500
ENST00000327619EYA2chr2045725807+ENST00000426004SYS1chr2043994259+38351262681330420
ENST00000317304EYA2chr2045725807+ENST00000372727SYS1chr2043994259+1306898101206398
ENST00000317304EYA2chr2045725807+ENST00000414310SYS1chr2043994259+1317898101206398
ENST00000317304EYA2chr2045725807+ENST00000243918SYS1chr2043994259+3307898101206398
ENST00000317304EYA2chr2045725807+ENST00000426004SYS1chr2043994259+347189810966318

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000357410ENST00000372727EYA2chr2045725807+SYS1chr2043994259+0.043628840.9563712
ENST00000357410ENST00000414310EYA2chr2045725807+SYS1chr2043994259+0.041740560.95825946
ENST00000357410ENST00000243918EYA2chr2045725807+SYS1chr2043994259+0.0136651690.9863348
ENST00000357410ENST00000426004EYA2chr2045725807+SYS1chr2043994259+0.0081571670.99184287
ENST00000327619ENST00000372727EYA2chr2045725807+SYS1chr2043994259+0.043628840.9563712
ENST00000327619ENST00000414310EYA2chr2045725807+SYS1chr2043994259+0.041740560.95825946
ENST00000327619ENST00000243918EYA2chr2045725807+SYS1chr2043994259+0.0136651690.9863348
ENST00000327619ENST00000426004EYA2chr2045725807+SYS1chr2043994259+0.0081571670.99184287
ENST00000317304ENST00000372727EYA2chr2045725807+SYS1chr2043994259+0.0413275140.9586725
ENST00000317304ENST00000414310EYA2chr2045725807+SYS1chr2043994259+0.038538810.96146125
ENST00000317304ENST00000243918EYA2chr2045725807+SYS1chr2043994259+0.0106599610.98934
ENST00000317304ENST00000426004EYA2chr2045725807+SYS1chr2043994259+0.0071908530.9928092

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Fusion Genomic Features for EYA2-SYS1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
EYA2chr2045725807+SYS1chr2043994258+0.015928120.9840719
EYA2chr2045725807+SYS1chr2043994258+0.015928120.9840719
EYA2chr2045725807+SYS1chr2043994258+0.015928120.9840719
EYA2chr2045725807+SYS1chr2043994258+0.015928120.9840719

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for EYA2-SYS1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:45725807/chr20:43994259)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSYS1chr20:45725807chr20:43994259ENST0000024391814113_13354157.0TransmembraneHelical
TgeneSYS1chr20:45725807chr20:43994259ENST000002439181465_8554157.0TransmembraneHelical
TgeneSYS1chr20:45725807chr20:43994259ENST000002439181491_11154157.0TransmembraneHelical
TgeneSYS1chr20:45725807chr20:43994259ENST0000037272725113_13354157.0TransmembraneHelical
TgeneSYS1chr20:45725807chr20:43994259ENST000003727272565_8554157.0TransmembraneHelical
TgeneSYS1chr20:45725807chr20:43994259ENST000003727272591_11154157.0TransmembraneHelical
TgeneSYS1chr20:45725807chr20:43994259ENST0000042600414113_1335477.0TransmembraneHelical
TgeneSYS1chr20:45725807chr20:43994259ENST000004260041465_855477.0TransmembraneHelical
TgeneSYS1chr20:45725807chr20:43994259ENST000004260041491_1115477.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSYS1chr20:45725807chr20:43994259ENST000002439181413_3354157.0TransmembraneHelical
TgeneSYS1chr20:45725807chr20:43994259ENST000003727272513_3354157.0TransmembraneHelical
TgeneSYS1chr20:45725807chr20:43994259ENST000004260041413_335477.0TransmembraneHelical


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Fusion Gene Sequence for EYA2-SYS1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>28053_28053_1_EYA2-SYS1_EYA2_chr20_45725807_ENST00000317304_SYS1_chr20_43994259_ENST00000243918_length(transcript)=3307nt_BP=898nt
GTACAAGGAAATGGTAGAACTAGTGATCTCACCCAGCCTCACTGTAAACAGCGATTGTCTGGATAAACTGAAGTTTAACCGTGCTGACGC
TGCTGTGTGGACTCTGAGTGACAGACAAGGCATCACCAAATCGGCCCCCCTGAGAGTGTCCCAGCTCTTCTCCAGATCTTGCCCACGTGT
CCTCCCCCGCCAGCCTTCCACAGCCATGGCAGCCTACGGCCAGACGCAGTACAGTGCGGGGATCCAGCAGGCTACCCCCTATACAGCTTA
CCCACCTCCAGCACAAGCCTATGGAATCCCTTCCTACAGCATCAAGACAGAAGACAGCTTGAACCATTCCCCTGGCCAGAGTGGATTCCT
CAGCTATGGCTCCAGCTTCAGCACCTCACCCACTGGACAGAGCCCATACACCTACCAGATGCACGGCACAACAGGGTTCTATCAAGGAGG
AAATGGACTGGGCAACGCAGCCGGTTTCGGGAGTGTGCACCAGGACTATCCTTCCTACCCCGGCTTCCCCCAGAGCCAGTACCCCCAGTA
TTACGGCTCATCCTACAACCCTCCCTACGTCCCGGCCAGCAGCATCTGCCCTTCGCCCCTCTCCACGTCCACCTACGTCCTCCAGGAGGC
ATCTCACAACGTCCCCAACCAGAGTTCCGAGTCACTTGCTGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGGGAGA
CACAGACAGGCCGCACCGGGCCTCCGACGGGAAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATGAGAT
TGAGCGTGTGTTCGTGTGGGACTTGGATGAGACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGAAGAT
CCTGGGCTTTTCCACCCCTCCAGGCCGGCTCTCCATGATGTCCTTCATCCTCAACGCCCTCACCTGTGCCCTGGGCTTGCTGTACTTCAT
CCGGCGAGGAAAGCAGTGTCTGGATTTCACTGTCACTGTCCATTTCTTTCACCTCCTGGGCTGCTGGTTCTACAGCTCCCGTTTCCCCTC
GGCGCTGACCTGGTGGCTGGTCCAAGCCGTGTGCATTGCACTCATGGCTGTCATCGGGGAGTACCTGTGCATGCGGACGGAGCTCAAGGA
GATACCCCTCAACTCAGCCCCTAAATCCAATGTCTAGAATCAGGCCCTTTGGACATCCTGCTGACACTTGGGCCCCTTAACACCTTGGGC
TGCTCAGACCCTCCAGATGAGGTCCAGCCCAGATCTGAGAGGAACCCTGGAAATGTGAAGTCTCTGTTGGTTTGGGAGAGATAGTGAGGG
CCTGTCAAAGAAGGCAGGTAGCAGTCAGCATGACAGCTGCAAGAATGACCTCTGTCTGTTGAAGCCTTGGTATCTGAGAGGTCAGGAAGG
GGACCTCTTTGAGGGTAATAACAGAATTGGAACCATGCCACTCTTGAGCCACAATACCTGTCACCAGCCTGTTGTTTTAAGAGAGAAAAA
AAATCAAGGATATCTGATTGGAGCAAACCACTTCTTTAGTCATCTGTCTTACCCCCCTGGGACAGCTGTTACCTTTGCAGTGTTGCCGAA
TCACAGCAGTTACCTTTGCAGTGTTGCCGAATCACAGCAGTTCTGTTGGAGAAACGCTTGGTTTCCGGATCCAGAGCCACAGAAAGAAAT
GTAGGTGTGAAGTATTAGGCTGCTGTCAGGGAGAGGATGGCAGATGGAGGCATCAAGCACAAGGAAAATGCACAACCTGTGCCCTGTTAT
ACACACGTTCATGTGCACCCAAGAACCTATGACTTTCTTCCAGTTCCTTCTACCAGGTCCCCATCCTGCTGCCAGCTCTCAACATAGCAG
GCCATAGGACCCAGAGAAGAATCCCAGCGTTGCTCAAAGTCTAACCATCATAAAGACACTGCCTGTCTTCTAGGAATGACCAGGCACCCA
GCTCCCACTGGACTCCAATTTTTTTTCCTGCCTTATTTAGAATTCTTTGGCGGGAAGGGTATGATGGGTTCCCAGAGACAAGAAGCCCAA
CCTTCTGGCCTGGGCTGTGCTGATAGTGCTGAGGGAGATAGGAATTTGCTGCTAAGATTTTTCTTTGGGGTGGAGTTTCCTCTGTGAGGG
GCTTGCAGCTATCCTTCCTGTGTATACAAATACAGTATTTTCCATGGTTCTGCCTGCACTTACTTTGTAATGCCACGGTTGAGATTGAGA
GAGATCAGCGCAGCCAGGCAAGGGAACTTTAAAGAATTATTAGGCCACCTTCTCCCTTTCCTGGACCCCAGAGTCATTCCTCCATTTGGT
TAAAATACTCAGTGCAGGGAACTCTTACATCCTGTCTCCTTCACTTGCAGCGTCCCCTGCTATGCCTCAGGTGAACCACATAATTCTTGG
GTTTCCGTTCCTACTTGCTAGTGATTTCTGAACATGTTCAATGGAGCGGCACACAGTCTAGACCCACTTCCGCATTGAAACCTTCACTGT
TCCTCTTTGGTTTCTTCAGAGCTTTCCCAAGAGAGCTGTCAGTTTTCAGCTGTCAGTAACACAAATGAGTTTATGGTAACACAAATGAGT
TTTGCTATCTCTCTGAGAAGCTCATCTGACCTCCTGACTCTCAGCCCTACAGAGTAGGGAGTTGATGCTGACAGGATGAAGATTTAGGAA
TAAATATGCCTGGGAAGAGACTGGGAAGGTTCTAGGGTGAGGCACCTCAGTAACTCATGGTACCTTGGCCAAGTTGGAAGGAAGCAGTTT
GTTAATGAGGCACAGTAATCCTGGCTGCAGGGTCTAGGAGGTAAGACCAGCTGGGATGACCTTCCCTGGGTTAATCAATTTCCCTCTAGA
CAACACAAACTGCAGGCATGTGACTAACTTTGAAAGAACACCCATCATGTGGCTGCTGTCACCCTTGACCAGCCGTGGTGGTGGTTACTC
CATCTGTGGTTGGAGCGCCTCTTTGGGATTCACTTCAAGGTCTTGTGCCTATTTTTCTGCATATCTTCTGTGATGACAAATCTCTGTCCC
CTGAGTGTTAATTTGATTTTTAGAAATGGCCAAAAGTCACGTGATCCAAACTTTTTTTCAGTAATATGGAGACTGAGCTGCATGGTAGTT
GGGGATCAAAAATATGTGACCTTAATGAGATTTTTATGATTTCTAAAGTAACAATAAAAGCAGTTTTTAGAGTTGAGTTCCAGAGAGGGC
AGGGCAATGGCAGTGACATGTTTGTCATTTTAATAATAAATAACATCTATTGAGTGCTTAAGAGGTG

>28053_28053_1_EYA2-SYS1_EYA2_chr20_45725807_ENST00000317304_SYS1_chr20_43994259_ENST00000243918_length(amino acids)=398AA_BP=296
MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPP
AQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERV
FVWDLDETIIIFHSLLTGTFASRYGKILGFSTPPGRLSMMSFILNALTCALGLLYFIRRGKQCLDFTVTVHFFHLLGCWFYSSRFPSALT
WWLVQAVCIALMAVIGEYLCMRTELKEIPLNSAPKSNV

--------------------------------------------------------------
>28053_28053_2_EYA2-SYS1_EYA2_chr20_45725807_ENST00000317304_SYS1_chr20_43994259_ENST00000372727_length(transcript)=1306nt_BP=898nt
GTACAAGGAAATGGTAGAACTAGTGATCTCACCCAGCCTCACTGTAAACAGCGATTGTCTGGATAAACTGAAGTTTAACCGTGCTGACGC
TGCTGTGTGGACTCTGAGTGACAGACAAGGCATCACCAAATCGGCCCCCCTGAGAGTGTCCCAGCTCTTCTCCAGATCTTGCCCACGTGT
CCTCCCCCGCCAGCCTTCCACAGCCATGGCAGCCTACGGCCAGACGCAGTACAGTGCGGGGATCCAGCAGGCTACCCCCTATACAGCTTA
CCCACCTCCAGCACAAGCCTATGGAATCCCTTCCTACAGCATCAAGACAGAAGACAGCTTGAACCATTCCCCTGGCCAGAGTGGATTCCT
CAGCTATGGCTCCAGCTTCAGCACCTCACCCACTGGACAGAGCCCATACACCTACCAGATGCACGGCACAACAGGGTTCTATCAAGGAGG
AAATGGACTGGGCAACGCAGCCGGTTTCGGGAGTGTGCACCAGGACTATCCTTCCTACCCCGGCTTCCCCCAGAGCCAGTACCCCCAGTA
TTACGGCTCATCCTACAACCCTCCCTACGTCCCGGCCAGCAGCATCTGCCCTTCGCCCCTCTCCACGTCCACCTACGTCCTCCAGGAGGC
ATCTCACAACGTCCCCAACCAGAGTTCCGAGTCACTTGCTGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGGGAGA
CACAGACAGGCCGCACCGGGCCTCCGACGGGAAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATGAGAT
TGAGCGTGTGTTCGTGTGGGACTTGGATGAGACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGAAGAT
CCTGGGCTTTTCCACCCCTCCAGGCCGGCTCTCCATGATGTCCTTCATCCTCAACGCCCTCACCTGTGCCCTGGGCTTGCTGTACTTCAT
CCGGCGAGGAAAGCAGTGTCTGGATTTCACTGTCACTGTCCATTTCTTTCACCTCCTGGGCTGCTGGTTCTACAGCTCCCGTTTCCCCTC
GGCGCTGACCTGGTGGCTGGTCCAAGCCGTGTGCATTGCACTCATGGCTGTCATCGGGGAGTACCTGTGCATGCGGACGGAGCTCAAGGA
GATACCCCTCAACTCAGCCCCTAAATCCAATGTCTAGAATCAGGCCCTTTGGACATCCTGCTGACACTTGGGCCCCTTAACACCTTGGGC
TGCTCAGACCCTCCAGATGAGGTCCAGCCCAGATCTGAGAGGAACC

>28053_28053_2_EYA2-SYS1_EYA2_chr20_45725807_ENST00000317304_SYS1_chr20_43994259_ENST00000372727_length(amino acids)=398AA_BP=296
MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPP
AQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERV
FVWDLDETIIIFHSLLTGTFASRYGKILGFSTPPGRLSMMSFILNALTCALGLLYFIRRGKQCLDFTVTVHFFHLLGCWFYSSRFPSALT
WWLVQAVCIALMAVIGEYLCMRTELKEIPLNSAPKSNV

--------------------------------------------------------------
>28053_28053_3_EYA2-SYS1_EYA2_chr20_45725807_ENST00000317304_SYS1_chr20_43994259_ENST00000414310_length(transcript)=1317nt_BP=898nt
GTACAAGGAAATGGTAGAACTAGTGATCTCACCCAGCCTCACTGTAAACAGCGATTGTCTGGATAAACTGAAGTTTAACCGTGCTGACGC
TGCTGTGTGGACTCTGAGTGACAGACAAGGCATCACCAAATCGGCCCCCCTGAGAGTGTCCCAGCTCTTCTCCAGATCTTGCCCACGTGT
CCTCCCCCGCCAGCCTTCCACAGCCATGGCAGCCTACGGCCAGACGCAGTACAGTGCGGGGATCCAGCAGGCTACCCCCTATACAGCTTA
CCCACCTCCAGCACAAGCCTATGGAATCCCTTCCTACAGCATCAAGACAGAAGACAGCTTGAACCATTCCCCTGGCCAGAGTGGATTCCT
CAGCTATGGCTCCAGCTTCAGCACCTCACCCACTGGACAGAGCCCATACACCTACCAGATGCACGGCACAACAGGGTTCTATCAAGGAGG
AAATGGACTGGGCAACGCAGCCGGTTTCGGGAGTGTGCACCAGGACTATCCTTCCTACCCCGGCTTCCCCCAGAGCCAGTACCCCCAGTA
TTACGGCTCATCCTACAACCCTCCCTACGTCCCGGCCAGCAGCATCTGCCCTTCGCCCCTCTCCACGTCCACCTACGTCCTCCAGGAGGC
ATCTCACAACGTCCCCAACCAGAGTTCCGAGTCACTTGCTGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGGGAGA
CACAGACAGGCCGCACCGGGCCTCCGACGGGAAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATGAGAT
TGAGCGTGTGTTCGTGTGGGACTTGGATGAGACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGAAGAT
CCTGGGCTTTTCCACCCCTCCAGGCCGGCTCTCCATGATGTCCTTCATCCTCAACGCCCTCACCTGTGCCCTGGGCTTGCTGTACTTCAT
CCGGCGAGGAAAGCAGTGTCTGGATTTCACTGTCACTGTCCATTTCTTTCACCTCCTGGGCTGCTGGTTCTACAGCTCCCGTTTCCCCTC
GGCGCTGACCTGGTGGCTGGTCCAAGCCGTGTGCATTGCACTCATGGCTGTCATCGGGGAGTACCTGTGCATGCGGACGGAGCTCAAGGA
GATACCCCTCAACTCAGCCCCTAAATCCAATGTCTAGAATCAGGCCCTTTGGACATCCTGCTGACACTTGGGCCCCTTAACACCTTGGGC
TGCTCAGACCCTCCAGATGAGGTCCAGCCCAGATCTGAGAGGAACCCTGGAAATGTG

>28053_28053_3_EYA2-SYS1_EYA2_chr20_45725807_ENST00000317304_SYS1_chr20_43994259_ENST00000414310_length(amino acids)=398AA_BP=296
MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPP
AQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERV
FVWDLDETIIIFHSLLTGTFASRYGKILGFSTPPGRLSMMSFILNALTCALGLLYFIRRGKQCLDFTVTVHFFHLLGCWFYSSRFPSALT
WWLVQAVCIALMAVIGEYLCMRTELKEIPLNSAPKSNV

--------------------------------------------------------------
>28053_28053_4_EYA2-SYS1_EYA2_chr20_45725807_ENST00000317304_SYS1_chr20_43994259_ENST00000426004_length(transcript)=3471nt_BP=898nt
GTACAAGGAAATGGTAGAACTAGTGATCTCACCCAGCCTCACTGTAAACAGCGATTGTCTGGATAAACTGAAGTTTAACCGTGCTGACGC
TGCTGTGTGGACTCTGAGTGACAGACAAGGCATCACCAAATCGGCCCCCCTGAGAGTGTCCCAGCTCTTCTCCAGATCTTGCCCACGTGT
CCTCCCCCGCCAGCCTTCCACAGCCATGGCAGCCTACGGCCAGACGCAGTACAGTGCGGGGATCCAGCAGGCTACCCCCTATACAGCTTA
CCCACCTCCAGCACAAGCCTATGGAATCCCTTCCTACAGCATCAAGACAGAAGACAGCTTGAACCATTCCCCTGGCCAGAGTGGATTCCT
CAGCTATGGCTCCAGCTTCAGCACCTCACCCACTGGACAGAGCCCATACACCTACCAGATGCACGGCACAACAGGGTTCTATCAAGGAGG
AAATGGACTGGGCAACGCAGCCGGTTTCGGGAGTGTGCACCAGGACTATCCTTCCTACCCCGGCTTCCCCCAGAGCCAGTACCCCCAGTA
TTACGGCTCATCCTACAACCCTCCCTACGTCCCGGCCAGCAGCATCTGCCCTTCGCCCCTCTCCACGTCCACCTACGTCCTCCAGGAGGC
ATCTCACAACGTCCCCAACCAGAGTTCCGAGTCACTTGCTGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGGGAGA
CACAGACAGGCCGCACCGGGCCTCCGACGGGAAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATGAGAT
TGAGCGTGTGTTCGTGTGGGACTTGGATGAGACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGAAGAT
CCTGGGCTTTTCCACCCCTCCAGGCCGGCTCTCCATGATGTCCTTCATCCTCAACGCCCTCACCTGACAGGGTCTTGCTCTCTTGCCCAG
GCTGGAGTGCAGTGGCGAAGTCACAGCTCACTGCAGCCTCGACTCCTGGGCTTAAGCGATCCTCCGACCTCAGCCTCCTGAGTAGCTGAT
ACTACAAGCGCAAGGCACCACATCTGGCTAATTTTTAAATTTTTTGTAGAGACAGTGTCTCATTATGTTGCCCAGGATGGTCTTGAACTC
CTGGCCTCAAGCAGTCTTCCTGCCTCGACCTCCCAAGGTGCTGGGATTACAGGCGTGAGCCACCATGCCTAGCCTGTTCAGAGTAAATCT
TATTTGAGGCATGAATCAATCAAACATAAATAGAGAGTTGAATTGATCTTAGAGGGAATGGGATGCAGCAAAGCCCTACTTGACCATCTC
CCCCCTCCCACATTTGGAAATCCTTAAACCCACTTATGTAGGCCTCTGACTGTGAGATTCAGAGCCACAGCAGTTTCCACCTCTGCTAAG
GCCTTCAGGCAGTGAGATGGCTCACTTCAGTGCCCCTCCTTCCACACATCTCCTAGCTGTATCCTGAGACGCCTCAACCTAGTCACTACC
CTTCTGTATGATGTTGGTCTAAGGCTTCCCCCTCTCTGGACATGAAGGCGGAGCCTCCCAGCACTACCAGCCACACACCACTCAAGACTC
CAGATCCTGAACCCTGACTCTGGGGCCCAGCTCTGGGCCTGGCTTGGGGCTTGCATCTCACCTAGCCTGGCAGTGTTGTTGTCACACCCA
CCTTGTATGGATGCCACATAGGCATTTCAAGTGATGCGGAGCAGAAGCGGGTGCAGCGGCGCTTGACCCAACGCAGGGTGGAGGATCTGC
ACATCACCCTGGGCGCCGGGAGGTGGATTCGTGTGGGCAGCCCCTCAAACCAGATCCACTGGTCGGCTACATCCAGCTGCTTCATGTGCC
CCATGGGAGTTCTATTGCGGTAGGGCTTAATGAAGATGACTCGGGGGCCCTCGGTGAGTGGTTGCCTCCCCTGGACTCCAGGGTTCAAGC
TATCATCCCTCGATGTCCTTGGAACCTCAGGCTCTATATGCTTTTCTTTCCGTGGCATTGCCGCCAATGACGTTTTCTCCTTGTTCCTCA
TCCCTGACTGCACCTGGGACTTCCACTCCTTGTACTCTTTTTTCTTAGGGTCCCCTGTGGACTCTAATTTCTTGGACTTGAGTTCCTTCT
CGGAGCACCCGATCTCCTGGAACTCTTCATTATTTTGTTTTGTTTTATTGCAGGCACTGTTTTCCCTGGCAGGGAGAGGAAAGGCAGTCA
GCACAGCAGGACCGAGGCCCTGGTTCCCGAGACAGTTGCTATGTAGCCAGCTCAGGGGAGCCTGTTAAGAAAGGCTAGAGGGGCCTGCAA
AGAAACTTCTCTACTGCCCAGAGGCCTTGTGCTGGTGTGAGGAGGTGTGATGAGCACTAGCAGAGGGATGTGAGAGATTGGGAAGGTGAA
AGCCATGACTAGTAGTTAAGGCCCCTAAGAATGAATATTGTCTACATCATCTGCCACTAGATTAGGGTTCTGTCTCTCTGGACTTCAGCT
GGGAGGGTGAACAGTCCAGTAGTTTTTCTAAATTGTGCTCCAAGAACCTTAGGGTTCTGAGGAGGTGTCTCAATGTCACCTCCCCTGACC
CACTGGGGCAGGATACCTCTCCCCAGCTCATAACAACACAATTGGGGCTTGGAAATAGATATTTGAACAGAGGTTTCACTGCTTTAATAA
AGTTGGAAAACTGTTCAAGACCAGCCTGGGCAACATGGTGAGACTCTGTCTCCATACAAAAAAAAAATTTTTAAGTTGGAAAATGATGGG
GCTAGATGATCCTGATCCTTCTAGCTCTATGTTTCCTGATTGCCTGCGACTAGAGGCCAAATCAGAAAGAGGAGCCCAGAAAGGTGGCCT
TGACAGAAATATTAAATGCTGAGACTTTCCCAAAGGGTGTCTGTAACAGACTGGGCCCCCTGCAAACCCCCAGTGGCAACACCATCCTAG
CCAAGGGCGTGGAGAGAGATGAGGCCTTGGGCTGCAGATAATGGCAATACTGTGATGATAATAATGGCTCCCGCTGATTGAGTCCTCGCT
CTATGCCAGACTCGGGACCCTTACAACTTGGGATCCTTACTATTTCTGTGAAGTAGAAGGCAGTGAAACAGAGTGGCTTACAGAGCACAG
GTGTTGGATTCAGACAAACGGGCTCAGATTCTGCTTCTGCCTCTTACCACCTGTGTGATTTGGGCAAGATATTTAACCTCTCAGAGCCTT
AGCTTCCTTATCTGTAAAACTAGGATAATTCTGTCTACCTAACAGGATTGTTGTGAAGAATAAACTAAATGGGAAAATTCTTAAGTGCTT
AACACTGTAGGATGGTACTTAGCAGGCACCAATCAATGTTAGCTTTCTTAATACTGTCATGTGACTTATGAGGAAACGGTTTGAACTTGT
CTCGGAGGCATGGTAAAAAAAAATAAAAATAAAAATAAATTAATAAAGAAA

>28053_28053_4_EYA2-SYS1_EYA2_chr20_45725807_ENST00000317304_SYS1_chr20_43994259_ENST00000426004_length(amino acids)=318AA_BP=296
MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPP
AQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERV
FVWDLDETIIIFHSLLTGTFASRYGKILGFSTPPGRLSMMSFILNALT

--------------------------------------------------------------
>28053_28053_5_EYA2-SYS1_EYA2_chr20_45725807_ENST00000327619_SYS1_chr20_43994259_ENST00000243918_length(transcript)=3671nt_BP=1262nt
GCGCGCTCTGCTCGGCTGCAGGCTCAGGAAGCGGCGCGGCGGCACGTGCTGGGCCAGAGCCCCGCGCCCTGCGTCCAGCCGCCGGGTGTG
TGCGCCCGCGTAGCCCAGCGTCGCGCCTCGGCGCCCCCACGCGCCCACGCAGCGGCGCGGGGACCCGGGCGGGGGCAGAGGGAGGGCCCG
GCCCAGGGAGGAGAAGGGGCCGGTCCTCCCGGCGCAGGCAGCAGCCGCGGCAGCCCAGGAGGCGGAGGCAGCGGCAACGGCAGAGACAGC
AACGTGCCCGCCGCAGTCAGCCCGGCCTCGTCGGACCCGCACCGGCCCGCCCGCCCGCCCGCACCGCGTCGGGGCGCCCTCTCCACTGCG
CGCGGTACAAGGAAATGGTAGAACTAGTGATCTCACCCAGCCTCACTGTAAACAGCGATTGTCTGGATAAACTGAAGTTTAACCGTGCTG
ACGCTGCTGTGTGGACTCTGAGTGACAGACAAGGCATCACCAAATCGGCCCCCCTGAGAGTGTCCCAGCTCTTCTCCAGATCTTGCCCAC
GTGTCCTCCCCCGCCAGCCTTCCACAGCCATGGCAGCCTACGGCCAGACGCAGTACAGTGCGGGGATCCAGCAGGCTACCCCCTATACAG
CTTACCCACCTCCAGCACAAGCCTATGGAATCCCTTCCTACAGCATCAAGACAGAAGACAGCTTGAACCATTCCCCTGGCCAGAGTGGAT
TCCTCAGCTATGGCTCCAGCTTCAGCACCTCACCCACTGGACAGAGCCCATACACCTACCAGATGCACGGCACAACAGGGTTCTATCAAG
GAGGAAATGGACTGGGCAACGCAGCCGGTTTCGGGAGTGTGCACCAGGACTATCCTTCCTACCCCGGCTTCCCCCAGAGCCAGTACCCCC
AGTATTACGGCTCATCCTACAACCCTCCCTACGTCCCGGCCAGCAGCATCTGCCCTTCGCCCCTCTCCACGTCCACCTACGTCCTCCAGG
AGGCATCTCACAACGTCCCCAACCAGAGTTCCGAGTCACTTGCTGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGG
GAGACACAGACAGGCCGCACCGGGCCTCCGACGGGAAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATG
AGATTGAGCGTGTGTTCGTGTGGGACTTGGATGAGACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGA
AGATCCTGGGCTTTTCCACCCCTCCAGGCCGGCTCTCCATGATGTCCTTCATCCTCAACGCCCTCACCTGTGCCCTGGGCTTGCTGTACT
TCATCCGGCGAGGAAAGCAGTGTCTGGATTTCACTGTCACTGTCCATTTCTTTCACCTCCTGGGCTGCTGGTTCTACAGCTCCCGTTTCC
CCTCGGCGCTGACCTGGTGGCTGGTCCAAGCCGTGTGCATTGCACTCATGGCTGTCATCGGGGAGTACCTGTGCATGCGGACGGAGCTCA
AGGAGATACCCCTCAACTCAGCCCCTAAATCCAATGTCTAGAATCAGGCCCTTTGGACATCCTGCTGACACTTGGGCCCCTTAACACCTT
GGGCTGCTCAGACCCTCCAGATGAGGTCCAGCCCAGATCTGAGAGGAACCCTGGAAATGTGAAGTCTCTGTTGGTTTGGGAGAGATAGTG
AGGGCCTGTCAAAGAAGGCAGGTAGCAGTCAGCATGACAGCTGCAAGAATGACCTCTGTCTGTTGAAGCCTTGGTATCTGAGAGGTCAGG
AAGGGGACCTCTTTGAGGGTAATAACAGAATTGGAACCATGCCACTCTTGAGCCACAATACCTGTCACCAGCCTGTTGTTTTAAGAGAGA
AAAAAAATCAAGGATATCTGATTGGAGCAAACCACTTCTTTAGTCATCTGTCTTACCCCCCTGGGACAGCTGTTACCTTTGCAGTGTTGC
CGAATCACAGCAGTTACCTTTGCAGTGTTGCCGAATCACAGCAGTTCTGTTGGAGAAACGCTTGGTTTCCGGATCCAGAGCCACAGAAAG
AAATGTAGGTGTGAAGTATTAGGCTGCTGTCAGGGAGAGGATGGCAGATGGAGGCATCAAGCACAAGGAAAATGCACAACCTGTGCCCTG
TTATACACACGTTCATGTGCACCCAAGAACCTATGACTTTCTTCCAGTTCCTTCTACCAGGTCCCCATCCTGCTGCCAGCTCTCAACATA
GCAGGCCATAGGACCCAGAGAAGAATCCCAGCGTTGCTCAAAGTCTAACCATCATAAAGACACTGCCTGTCTTCTAGGAATGACCAGGCA
CCCAGCTCCCACTGGACTCCAATTTTTTTTCCTGCCTTATTTAGAATTCTTTGGCGGGAAGGGTATGATGGGTTCCCAGAGACAAGAAGC
CCAACCTTCTGGCCTGGGCTGTGCTGATAGTGCTGAGGGAGATAGGAATTTGCTGCTAAGATTTTTCTTTGGGGTGGAGTTTCCTCTGTG
AGGGGCTTGCAGCTATCCTTCCTGTGTATACAAATACAGTATTTTCCATGGTTCTGCCTGCACTTACTTTGTAATGCCACGGTTGAGATT
GAGAGAGATCAGCGCAGCCAGGCAAGGGAACTTTAAAGAATTATTAGGCCACCTTCTCCCTTTCCTGGACCCCAGAGTCATTCCTCCATT
TGGTTAAAATACTCAGTGCAGGGAACTCTTACATCCTGTCTCCTTCACTTGCAGCGTCCCCTGCTATGCCTCAGGTGAACCACATAATTC
TTGGGTTTCCGTTCCTACTTGCTAGTGATTTCTGAACATGTTCAATGGAGCGGCACACAGTCTAGACCCACTTCCGCATTGAAACCTTCA
CTGTTCCTCTTTGGTTTCTTCAGAGCTTTCCCAAGAGAGCTGTCAGTTTTCAGCTGTCAGTAACACAAATGAGTTTATGGTAACACAAAT
GAGTTTTGCTATCTCTCTGAGAAGCTCATCTGACCTCCTGACTCTCAGCCCTACAGAGTAGGGAGTTGATGCTGACAGGATGAAGATTTA
GGAATAAATATGCCTGGGAAGAGACTGGGAAGGTTCTAGGGTGAGGCACCTCAGTAACTCATGGTACCTTGGCCAAGTTGGAAGGAAGCA
GTTTGTTAATGAGGCACAGTAATCCTGGCTGCAGGGTCTAGGAGGTAAGACCAGCTGGGATGACCTTCCCTGGGTTAATCAATTTCCCTC
TAGACAACACAAACTGCAGGCATGTGACTAACTTTGAAAGAACACCCATCATGTGGCTGCTGTCACCCTTGACCAGCCGTGGTGGTGGTT
ACTCCATCTGTGGTTGGAGCGCCTCTTTGGGATTCACTTCAAGGTCTTGTGCCTATTTTTCTGCATATCTTCTGTGATGACAAATCTCTG
TCCCCTGAGTGTTAATTTGATTTTTAGAAATGGCCAAAAGTCACGTGATCCAAACTTTTTTTCAGTAATATGGAGACTGAGCTGCATGGT
AGTTGGGGATCAAAAATATGTGACCTTAATGAGATTTTTATGATTTCTAAAGTAACAATAAAAGCAGTTTTTAGAGTTGAGTTCCAGAGA
GGGCAGGGCAATGGCAGTGACATGTTTGTCATTTTAATAATAAATAACATCTATTGAGTGCTTAAGAGGTG

>28053_28053_5_EYA2-SYS1_EYA2_chr20_45725807_ENST00000327619_SYS1_chr20_43994259_ENST00000243918_length(amino acids)=500AA_BP=398
MRPAAGCVRPRSPASRLGAPTRPRSGAGTRAGAEGGPGPGRRRGRSSRRRQQPRQPRRRRQRQRQRQQRARRSQPGLVGPAPARPPARTA
SGRPLHCARYKEMVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGI
QQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG
FPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSD
PSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKILGFSTPPGRLSMMSFILNALTCALGLLYFIRRGKQCLDFTVTVHFFHLLGC
WFYSSRFPSALTWWLVQAVCIALMAVIGEYLCMRTELKEIPLNSAPKSNV

--------------------------------------------------------------
>28053_28053_6_EYA2-SYS1_EYA2_chr20_45725807_ENST00000327619_SYS1_chr20_43994259_ENST00000372727_length(transcript)=1670nt_BP=1262nt
GCGCGCTCTGCTCGGCTGCAGGCTCAGGAAGCGGCGCGGCGGCACGTGCTGGGCCAGAGCCCCGCGCCCTGCGTCCAGCCGCCGGGTGTG
TGCGCCCGCGTAGCCCAGCGTCGCGCCTCGGCGCCCCCACGCGCCCACGCAGCGGCGCGGGGACCCGGGCGGGGGCAGAGGGAGGGCCCG
GCCCAGGGAGGAGAAGGGGCCGGTCCTCCCGGCGCAGGCAGCAGCCGCGGCAGCCCAGGAGGCGGAGGCAGCGGCAACGGCAGAGACAGC
AACGTGCCCGCCGCAGTCAGCCCGGCCTCGTCGGACCCGCACCGGCCCGCCCGCCCGCCCGCACCGCGTCGGGGCGCCCTCTCCACTGCG
CGCGGTACAAGGAAATGGTAGAACTAGTGATCTCACCCAGCCTCACTGTAAACAGCGATTGTCTGGATAAACTGAAGTTTAACCGTGCTG
ACGCTGCTGTGTGGACTCTGAGTGACAGACAAGGCATCACCAAATCGGCCCCCCTGAGAGTGTCCCAGCTCTTCTCCAGATCTTGCCCAC
GTGTCCTCCCCCGCCAGCCTTCCACAGCCATGGCAGCCTACGGCCAGACGCAGTACAGTGCGGGGATCCAGCAGGCTACCCCCTATACAG
CTTACCCACCTCCAGCACAAGCCTATGGAATCCCTTCCTACAGCATCAAGACAGAAGACAGCTTGAACCATTCCCCTGGCCAGAGTGGAT
TCCTCAGCTATGGCTCCAGCTTCAGCACCTCACCCACTGGACAGAGCCCATACACCTACCAGATGCACGGCACAACAGGGTTCTATCAAG
GAGGAAATGGACTGGGCAACGCAGCCGGTTTCGGGAGTGTGCACCAGGACTATCCTTCCTACCCCGGCTTCCCCCAGAGCCAGTACCCCC
AGTATTACGGCTCATCCTACAACCCTCCCTACGTCCCGGCCAGCAGCATCTGCCCTTCGCCCCTCTCCACGTCCACCTACGTCCTCCAGG
AGGCATCTCACAACGTCCCCAACCAGAGTTCCGAGTCACTTGCTGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGG
GAGACACAGACAGGCCGCACCGGGCCTCCGACGGGAAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATG
AGATTGAGCGTGTGTTCGTGTGGGACTTGGATGAGACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGA
AGATCCTGGGCTTTTCCACCCCTCCAGGCCGGCTCTCCATGATGTCCTTCATCCTCAACGCCCTCACCTGTGCCCTGGGCTTGCTGTACT
TCATCCGGCGAGGAAAGCAGTGTCTGGATTTCACTGTCACTGTCCATTTCTTTCACCTCCTGGGCTGCTGGTTCTACAGCTCCCGTTTCC
CCTCGGCGCTGACCTGGTGGCTGGTCCAAGCCGTGTGCATTGCACTCATGGCTGTCATCGGGGAGTACCTGTGCATGCGGACGGAGCTCA
AGGAGATACCCCTCAACTCAGCCCCTAAATCCAATGTCTAGAATCAGGCCCTTTGGACATCCTGCTGACACTTGGGCCCCTTAACACCTT
GGGCTGCTCAGACCCTCCAGATGAGGTCCAGCCCAGATCTGAGAGGAACC

>28053_28053_6_EYA2-SYS1_EYA2_chr20_45725807_ENST00000327619_SYS1_chr20_43994259_ENST00000372727_length(amino acids)=500AA_BP=398
MRPAAGCVRPRSPASRLGAPTRPRSGAGTRAGAEGGPGPGRRRGRSSRRRQQPRQPRRRRQRQRQRQQRARRSQPGLVGPAPARPPARTA
SGRPLHCARYKEMVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGI
QQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG
FPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSD
PSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKILGFSTPPGRLSMMSFILNALTCALGLLYFIRRGKQCLDFTVTVHFFHLLGC
WFYSSRFPSALTWWLVQAVCIALMAVIGEYLCMRTELKEIPLNSAPKSNV

--------------------------------------------------------------
>28053_28053_7_EYA2-SYS1_EYA2_chr20_45725807_ENST00000327619_SYS1_chr20_43994259_ENST00000414310_length(transcript)=1681nt_BP=1262nt
GCGCGCTCTGCTCGGCTGCAGGCTCAGGAAGCGGCGCGGCGGCACGTGCTGGGCCAGAGCCCCGCGCCCTGCGTCCAGCCGCCGGGTGTG
TGCGCCCGCGTAGCCCAGCGTCGCGCCTCGGCGCCCCCACGCGCCCACGCAGCGGCGCGGGGACCCGGGCGGGGGCAGAGGGAGGGCCCG
GCCCAGGGAGGAGAAGGGGCCGGTCCTCCCGGCGCAGGCAGCAGCCGCGGCAGCCCAGGAGGCGGAGGCAGCGGCAACGGCAGAGACAGC
AACGTGCCCGCCGCAGTCAGCCCGGCCTCGTCGGACCCGCACCGGCCCGCCCGCCCGCCCGCACCGCGTCGGGGCGCCCTCTCCACTGCG
CGCGGTACAAGGAAATGGTAGAACTAGTGATCTCACCCAGCCTCACTGTAAACAGCGATTGTCTGGATAAACTGAAGTTTAACCGTGCTG
ACGCTGCTGTGTGGACTCTGAGTGACAGACAAGGCATCACCAAATCGGCCCCCCTGAGAGTGTCCCAGCTCTTCTCCAGATCTTGCCCAC
GTGTCCTCCCCCGCCAGCCTTCCACAGCCATGGCAGCCTACGGCCAGACGCAGTACAGTGCGGGGATCCAGCAGGCTACCCCCTATACAG
CTTACCCACCTCCAGCACAAGCCTATGGAATCCCTTCCTACAGCATCAAGACAGAAGACAGCTTGAACCATTCCCCTGGCCAGAGTGGAT
TCCTCAGCTATGGCTCCAGCTTCAGCACCTCACCCACTGGACAGAGCCCATACACCTACCAGATGCACGGCACAACAGGGTTCTATCAAG
GAGGAAATGGACTGGGCAACGCAGCCGGTTTCGGGAGTGTGCACCAGGACTATCCTTCCTACCCCGGCTTCCCCCAGAGCCAGTACCCCC
AGTATTACGGCTCATCCTACAACCCTCCCTACGTCCCGGCCAGCAGCATCTGCCCTTCGCCCCTCTCCACGTCCACCTACGTCCTCCAGG
AGGCATCTCACAACGTCCCCAACCAGAGTTCCGAGTCACTTGCTGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGG
GAGACACAGACAGGCCGCACCGGGCCTCCGACGGGAAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATG
AGATTGAGCGTGTGTTCGTGTGGGACTTGGATGAGACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGA
AGATCCTGGGCTTTTCCACCCCTCCAGGCCGGCTCTCCATGATGTCCTTCATCCTCAACGCCCTCACCTGTGCCCTGGGCTTGCTGTACT
TCATCCGGCGAGGAAAGCAGTGTCTGGATTTCACTGTCACTGTCCATTTCTTTCACCTCCTGGGCTGCTGGTTCTACAGCTCCCGTTTCC
CCTCGGCGCTGACCTGGTGGCTGGTCCAAGCCGTGTGCATTGCACTCATGGCTGTCATCGGGGAGTACCTGTGCATGCGGACGGAGCTCA
AGGAGATACCCCTCAACTCAGCCCCTAAATCCAATGTCTAGAATCAGGCCCTTTGGACATCCTGCTGACACTTGGGCCCCTTAACACCTT
GGGCTGCTCAGACCCTCCAGATGAGGTCCAGCCCAGATCTGAGAGGAACCCTGGAAATGTG

>28053_28053_7_EYA2-SYS1_EYA2_chr20_45725807_ENST00000327619_SYS1_chr20_43994259_ENST00000414310_length(amino acids)=500AA_BP=398
MRPAAGCVRPRSPASRLGAPTRPRSGAGTRAGAEGGPGPGRRRGRSSRRRQQPRQPRRRRQRQRQRQQRARRSQPGLVGPAPARPPARTA
SGRPLHCARYKEMVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGI
QQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG
FPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSD
PSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKILGFSTPPGRLSMMSFILNALTCALGLLYFIRRGKQCLDFTVTVHFFHLLGC
WFYSSRFPSALTWWLVQAVCIALMAVIGEYLCMRTELKEIPLNSAPKSNV

--------------------------------------------------------------
>28053_28053_8_EYA2-SYS1_EYA2_chr20_45725807_ENST00000327619_SYS1_chr20_43994259_ENST00000426004_length(transcript)=3835nt_BP=1262nt
GCGCGCTCTGCTCGGCTGCAGGCTCAGGAAGCGGCGCGGCGGCACGTGCTGGGCCAGAGCCCCGCGCCCTGCGTCCAGCCGCCGGGTGTG
TGCGCCCGCGTAGCCCAGCGTCGCGCCTCGGCGCCCCCACGCGCCCACGCAGCGGCGCGGGGACCCGGGCGGGGGCAGAGGGAGGGCCCG
GCCCAGGGAGGAGAAGGGGCCGGTCCTCCCGGCGCAGGCAGCAGCCGCGGCAGCCCAGGAGGCGGAGGCAGCGGCAACGGCAGAGACAGC
AACGTGCCCGCCGCAGTCAGCCCGGCCTCGTCGGACCCGCACCGGCCCGCCCGCCCGCCCGCACCGCGTCGGGGCGCCCTCTCCACTGCG
CGCGGTACAAGGAAATGGTAGAACTAGTGATCTCACCCAGCCTCACTGTAAACAGCGATTGTCTGGATAAACTGAAGTTTAACCGTGCTG
ACGCTGCTGTGTGGACTCTGAGTGACAGACAAGGCATCACCAAATCGGCCCCCCTGAGAGTGTCCCAGCTCTTCTCCAGATCTTGCCCAC
GTGTCCTCCCCCGCCAGCCTTCCACAGCCATGGCAGCCTACGGCCAGACGCAGTACAGTGCGGGGATCCAGCAGGCTACCCCCTATACAG
CTTACCCACCTCCAGCACAAGCCTATGGAATCCCTTCCTACAGCATCAAGACAGAAGACAGCTTGAACCATTCCCCTGGCCAGAGTGGAT
TCCTCAGCTATGGCTCCAGCTTCAGCACCTCACCCACTGGACAGAGCCCATACACCTACCAGATGCACGGCACAACAGGGTTCTATCAAG
GAGGAAATGGACTGGGCAACGCAGCCGGTTTCGGGAGTGTGCACCAGGACTATCCTTCCTACCCCGGCTTCCCCCAGAGCCAGTACCCCC
AGTATTACGGCTCATCCTACAACCCTCCCTACGTCCCGGCCAGCAGCATCTGCCCTTCGCCCCTCTCCACGTCCACCTACGTCCTCCAGG
AGGCATCTCACAACGTCCCCAACCAGAGTTCCGAGTCACTTGCTGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGG
GAGACACAGACAGGCCGCACCGGGCCTCCGACGGGAAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATG
AGATTGAGCGTGTGTTCGTGTGGGACTTGGATGAGACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGA
AGATCCTGGGCTTTTCCACCCCTCCAGGCCGGCTCTCCATGATGTCCTTCATCCTCAACGCCCTCACCTGACAGGGTCTTGCTCTCTTGC
CCAGGCTGGAGTGCAGTGGCGAAGTCACAGCTCACTGCAGCCTCGACTCCTGGGCTTAAGCGATCCTCCGACCTCAGCCTCCTGAGTAGC
TGATACTACAAGCGCAAGGCACCACATCTGGCTAATTTTTAAATTTTTTGTAGAGACAGTGTCTCATTATGTTGCCCAGGATGGTCTTGA
ACTCCTGGCCTCAAGCAGTCTTCCTGCCTCGACCTCCCAAGGTGCTGGGATTACAGGCGTGAGCCACCATGCCTAGCCTGTTCAGAGTAA
ATCTTATTTGAGGCATGAATCAATCAAACATAAATAGAGAGTTGAATTGATCTTAGAGGGAATGGGATGCAGCAAAGCCCTACTTGACCA
TCTCCCCCCTCCCACATTTGGAAATCCTTAAACCCACTTATGTAGGCCTCTGACTGTGAGATTCAGAGCCACAGCAGTTTCCACCTCTGC
TAAGGCCTTCAGGCAGTGAGATGGCTCACTTCAGTGCCCCTCCTTCCACACATCTCCTAGCTGTATCCTGAGACGCCTCAACCTAGTCAC
TACCCTTCTGTATGATGTTGGTCTAAGGCTTCCCCCTCTCTGGACATGAAGGCGGAGCCTCCCAGCACTACCAGCCACACACCACTCAAG
ACTCCAGATCCTGAACCCTGACTCTGGGGCCCAGCTCTGGGCCTGGCTTGGGGCTTGCATCTCACCTAGCCTGGCAGTGTTGTTGTCACA
CCCACCTTGTATGGATGCCACATAGGCATTTCAAGTGATGCGGAGCAGAAGCGGGTGCAGCGGCGCTTGACCCAACGCAGGGTGGAGGAT
CTGCACATCACCCTGGGCGCCGGGAGGTGGATTCGTGTGGGCAGCCCCTCAAACCAGATCCACTGGTCGGCTACATCCAGCTGCTTCATG
TGCCCCATGGGAGTTCTATTGCGGTAGGGCTTAATGAAGATGACTCGGGGGCCCTCGGTGAGTGGTTGCCTCCCCTGGACTCCAGGGTTC
AAGCTATCATCCCTCGATGTCCTTGGAACCTCAGGCTCTATATGCTTTTCTTTCCGTGGCATTGCCGCCAATGACGTTTTCTCCTTGTTC
CTCATCCCTGACTGCACCTGGGACTTCCACTCCTTGTACTCTTTTTTCTTAGGGTCCCCTGTGGACTCTAATTTCTTGGACTTGAGTTCC
TTCTCGGAGCACCCGATCTCCTGGAACTCTTCATTATTTTGTTTTGTTTTATTGCAGGCACTGTTTTCCCTGGCAGGGAGAGGAAAGGCA
GTCAGCACAGCAGGACCGAGGCCCTGGTTCCCGAGACAGTTGCTATGTAGCCAGCTCAGGGGAGCCTGTTAAGAAAGGCTAGAGGGGCCT
GCAAAGAAACTTCTCTACTGCCCAGAGGCCTTGTGCTGGTGTGAGGAGGTGTGATGAGCACTAGCAGAGGGATGTGAGAGATTGGGAAGG
TGAAAGCCATGACTAGTAGTTAAGGCCCCTAAGAATGAATATTGTCTACATCATCTGCCACTAGATTAGGGTTCTGTCTCTCTGGACTTC
AGCTGGGAGGGTGAACAGTCCAGTAGTTTTTCTAAATTGTGCTCCAAGAACCTTAGGGTTCTGAGGAGGTGTCTCAATGTCACCTCCCCT
GACCCACTGGGGCAGGATACCTCTCCCCAGCTCATAACAACACAATTGGGGCTTGGAAATAGATATTTGAACAGAGGTTTCACTGCTTTA
ATAAAGTTGGAAAACTGTTCAAGACCAGCCTGGGCAACATGGTGAGACTCTGTCTCCATACAAAAAAAAAATTTTTAAGTTGGAAAATGA
TGGGGCTAGATGATCCTGATCCTTCTAGCTCTATGTTTCCTGATTGCCTGCGACTAGAGGCCAAATCAGAAAGAGGAGCCCAGAAAGGTG
GCCTTGACAGAAATATTAAATGCTGAGACTTTCCCAAAGGGTGTCTGTAACAGACTGGGCCCCCTGCAAACCCCCAGTGGCAACACCATC
CTAGCCAAGGGCGTGGAGAGAGATGAGGCCTTGGGCTGCAGATAATGGCAATACTGTGATGATAATAATGGCTCCCGCTGATTGAGTCCT
CGCTCTATGCCAGACTCGGGACCCTTACAACTTGGGATCCTTACTATTTCTGTGAAGTAGAAGGCAGTGAAACAGAGTGGCTTACAGAGC
ACAGGTGTTGGATTCAGACAAACGGGCTCAGATTCTGCTTCTGCCTCTTACCACCTGTGTGATTTGGGCAAGATATTTAACCTCTCAGAG
CCTTAGCTTCCTTATCTGTAAAACTAGGATAATTCTGTCTACCTAACAGGATTGTTGTGAAGAATAAACTAAATGGGAAAATTCTTAAGT
GCTTAACACTGTAGGATGGTACTTAGCAGGCACCAATCAATGTTAGCTTTCTTAATACTGTCATGTGACTTATGAGGAAACGGTTTGAAC
TTGTCTCGGAGGCATGGTAAAAAAAAATAAAAATAAAAATAAATTAATAAAGAAA

>28053_28053_8_EYA2-SYS1_EYA2_chr20_45725807_ENST00000327619_SYS1_chr20_43994259_ENST00000426004_length(amino acids)=420AA_BP=398
MRPAAGCVRPRSPASRLGAPTRPRSGAGTRAGAEGGPGPGRRRGRSSRRRQQPRQPRRRRQRQRQRQQRARRSQPGLVGPAPARPPARTA
SGRPLHCARYKEMVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGI
QQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG
FPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSD
PSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKILGFSTPPGRLSMMSFILNALT

--------------------------------------------------------------
>28053_28053_9_EYA2-SYS1_EYA2_chr20_45725807_ENST00000357410_SYS1_chr20_43994259_ENST00000243918_length(transcript)=3671nt_BP=1262nt
GCGCGCTCTGCTCGGCTGCAGGCTCAGGAAGCGGCGCGGCGGCACGTGCTGGGCCAGAGCCCCGCGCCCTGCGTCCAGCCGCCGGGTGTG
TGCGCCCGCGTAGCCCAGCGTCGCGCCTCGGCGCCCCCACGCGCCCACGCAGCGGCGCGGGGACCCGGGCGGGGGCAGAGGGAGGGCCCG
GCCCAGGGAGGAGAAGGGGCCGGTCCTCCCGGCGCAGGCAGCAGCCGCGGCAGCCCAGGAGGCGGAGGCAGCGGCAACGGCAGAGACAGC
AACGTGCCCGCCGCAGTCAGCCCGGCCTCGTCGGACCCGCACCGGCCCGCCCGCCCGCCCGCACCGCGTCGGGGCGCCCTCTCCACTGCG
CGCGGTACAAGGAAATGGTAGAACTAGTGATCTCACCCAGCCTCACTGTAAACAGCGATTGTCTGGATAAACTGAAGTTTAACCGTGCTG
ACGCTGCTGTGTGGACTCTGAGTGACAGACAAGGCATCACCAAATCGGCCCCCCTGAGAGTGTCCCAGCTCTTCTCCAGATCTTGCCCAC
GTGTCCTCCCCCGCCAGCCTTCCACAGCCATGGCAGCCTACGGCCAGACGCAGTACAGTGCGGGGATCCAGCAGGCTACCCCCTATACAG
CTTACCCACCTCCAGCACAAGCCTATGGAATCCCTTCCTACAGCATCAAGACAGAAGACAGCTTGAACCATTCCCCTGGCCAGAGTGGAT
TCCTCAGCTATGGCTCCAGCTTCAGCACCTCACCCACTGGACAGAGCCCATACACCTACCAGATGCACGGCACAACAGGGTTCTATCAAG
GAGGAAATGGACTGGGCAACGCAGCCGGTTTCGGGAGTGTGCACCAGGACTATCCTTCCTACCCCGGCTTCCCCCAGAGCCAGTACCCCC
AGTATTACGGCTCATCCTACAACCCTCCCTACGTCCCGGCCAGCAGCATCTGCCCTTCGCCCCTCTCCACGTCCACCTACGTCCTCCAGG
AGGCATCTCACAACGTCCCCAACCAGAGTTCCGAGTCACTTGCTGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGG
GAGACACAGACAGGCCGCACCGGGCCTCCGACGGGAAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATG
AGATTGAGCGTGTGTTCGTGTGGGACTTGGATGAGACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGA
AGATCCTGGGCTTTTCCACCCCTCCAGGCCGGCTCTCCATGATGTCCTTCATCCTCAACGCCCTCACCTGTGCCCTGGGCTTGCTGTACT
TCATCCGGCGAGGAAAGCAGTGTCTGGATTTCACTGTCACTGTCCATTTCTTTCACCTCCTGGGCTGCTGGTTCTACAGCTCCCGTTTCC
CCTCGGCGCTGACCTGGTGGCTGGTCCAAGCCGTGTGCATTGCACTCATGGCTGTCATCGGGGAGTACCTGTGCATGCGGACGGAGCTCA
AGGAGATACCCCTCAACTCAGCCCCTAAATCCAATGTCTAGAATCAGGCCCTTTGGACATCCTGCTGACACTTGGGCCCCTTAACACCTT
GGGCTGCTCAGACCCTCCAGATGAGGTCCAGCCCAGATCTGAGAGGAACCCTGGAAATGTGAAGTCTCTGTTGGTTTGGGAGAGATAGTG
AGGGCCTGTCAAAGAAGGCAGGTAGCAGTCAGCATGACAGCTGCAAGAATGACCTCTGTCTGTTGAAGCCTTGGTATCTGAGAGGTCAGG
AAGGGGACCTCTTTGAGGGTAATAACAGAATTGGAACCATGCCACTCTTGAGCCACAATACCTGTCACCAGCCTGTTGTTTTAAGAGAGA
AAAAAAATCAAGGATATCTGATTGGAGCAAACCACTTCTTTAGTCATCTGTCTTACCCCCCTGGGACAGCTGTTACCTTTGCAGTGTTGC
CGAATCACAGCAGTTACCTTTGCAGTGTTGCCGAATCACAGCAGTTCTGTTGGAGAAACGCTTGGTTTCCGGATCCAGAGCCACAGAAAG
AAATGTAGGTGTGAAGTATTAGGCTGCTGTCAGGGAGAGGATGGCAGATGGAGGCATCAAGCACAAGGAAAATGCACAACCTGTGCCCTG
TTATACACACGTTCATGTGCACCCAAGAACCTATGACTTTCTTCCAGTTCCTTCTACCAGGTCCCCATCCTGCTGCCAGCTCTCAACATA
GCAGGCCATAGGACCCAGAGAAGAATCCCAGCGTTGCTCAAAGTCTAACCATCATAAAGACACTGCCTGTCTTCTAGGAATGACCAGGCA
CCCAGCTCCCACTGGACTCCAATTTTTTTTCCTGCCTTATTTAGAATTCTTTGGCGGGAAGGGTATGATGGGTTCCCAGAGACAAGAAGC
CCAACCTTCTGGCCTGGGCTGTGCTGATAGTGCTGAGGGAGATAGGAATTTGCTGCTAAGATTTTTCTTTGGGGTGGAGTTTCCTCTGTG
AGGGGCTTGCAGCTATCCTTCCTGTGTATACAAATACAGTATTTTCCATGGTTCTGCCTGCACTTACTTTGTAATGCCACGGTTGAGATT
GAGAGAGATCAGCGCAGCCAGGCAAGGGAACTTTAAAGAATTATTAGGCCACCTTCTCCCTTTCCTGGACCCCAGAGTCATTCCTCCATT
TGGTTAAAATACTCAGTGCAGGGAACTCTTACATCCTGTCTCCTTCACTTGCAGCGTCCCCTGCTATGCCTCAGGTGAACCACATAATTC
TTGGGTTTCCGTTCCTACTTGCTAGTGATTTCTGAACATGTTCAATGGAGCGGCACACAGTCTAGACCCACTTCCGCATTGAAACCTTCA
CTGTTCCTCTTTGGTTTCTTCAGAGCTTTCCCAAGAGAGCTGTCAGTTTTCAGCTGTCAGTAACACAAATGAGTTTATGGTAACACAAAT
GAGTTTTGCTATCTCTCTGAGAAGCTCATCTGACCTCCTGACTCTCAGCCCTACAGAGTAGGGAGTTGATGCTGACAGGATGAAGATTTA
GGAATAAATATGCCTGGGAAGAGACTGGGAAGGTTCTAGGGTGAGGCACCTCAGTAACTCATGGTACCTTGGCCAAGTTGGAAGGAAGCA
GTTTGTTAATGAGGCACAGTAATCCTGGCTGCAGGGTCTAGGAGGTAAGACCAGCTGGGATGACCTTCCCTGGGTTAATCAATTTCCCTC
TAGACAACACAAACTGCAGGCATGTGACTAACTTTGAAAGAACACCCATCATGTGGCTGCTGTCACCCTTGACCAGCCGTGGTGGTGGTT
ACTCCATCTGTGGTTGGAGCGCCTCTTTGGGATTCACTTCAAGGTCTTGTGCCTATTTTTCTGCATATCTTCTGTGATGACAAATCTCTG
TCCCCTGAGTGTTAATTTGATTTTTAGAAATGGCCAAAAGTCACGTGATCCAAACTTTTTTTCAGTAATATGGAGACTGAGCTGCATGGT
AGTTGGGGATCAAAAATATGTGACCTTAATGAGATTTTTATGATTTCTAAAGTAACAATAAAAGCAGTTTTTAGAGTTGAGTTCCAGAGA
GGGCAGGGCAATGGCAGTGACATGTTTGTCATTTTAATAATAAATAACATCTATTGAGTGCTTAAGAGGTG

>28053_28053_9_EYA2-SYS1_EYA2_chr20_45725807_ENST00000357410_SYS1_chr20_43994259_ENST00000243918_length(amino acids)=500AA_BP=398
MRPAAGCVRPRSPASRLGAPTRPRSGAGTRAGAEGGPGPGRRRGRSSRRRQQPRQPRRRRQRQRQRQQRARRSQPGLVGPAPARPPARTA
SGRPLHCARYKEMVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGI
QQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG
FPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSD
PSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKILGFSTPPGRLSMMSFILNALTCALGLLYFIRRGKQCLDFTVTVHFFHLLGC
WFYSSRFPSALTWWLVQAVCIALMAVIGEYLCMRTELKEIPLNSAPKSNV

--------------------------------------------------------------
>28053_28053_10_EYA2-SYS1_EYA2_chr20_45725807_ENST00000357410_SYS1_chr20_43994259_ENST00000372727_length(transcript)=1670nt_BP=1262nt
GCGCGCTCTGCTCGGCTGCAGGCTCAGGAAGCGGCGCGGCGGCACGTGCTGGGCCAGAGCCCCGCGCCCTGCGTCCAGCCGCCGGGTGTG
TGCGCCCGCGTAGCCCAGCGTCGCGCCTCGGCGCCCCCACGCGCCCACGCAGCGGCGCGGGGACCCGGGCGGGGGCAGAGGGAGGGCCCG
GCCCAGGGAGGAGAAGGGGCCGGTCCTCCCGGCGCAGGCAGCAGCCGCGGCAGCCCAGGAGGCGGAGGCAGCGGCAACGGCAGAGACAGC
AACGTGCCCGCCGCAGTCAGCCCGGCCTCGTCGGACCCGCACCGGCCCGCCCGCCCGCCCGCACCGCGTCGGGGCGCCCTCTCCACTGCG
CGCGGTACAAGGAAATGGTAGAACTAGTGATCTCACCCAGCCTCACTGTAAACAGCGATTGTCTGGATAAACTGAAGTTTAACCGTGCTG
ACGCTGCTGTGTGGACTCTGAGTGACAGACAAGGCATCACCAAATCGGCCCCCCTGAGAGTGTCCCAGCTCTTCTCCAGATCTTGCCCAC
GTGTCCTCCCCCGCCAGCCTTCCACAGCCATGGCAGCCTACGGCCAGACGCAGTACAGTGCGGGGATCCAGCAGGCTACCCCCTATACAG
CTTACCCACCTCCAGCACAAGCCTATGGAATCCCTTCCTACAGCATCAAGACAGAAGACAGCTTGAACCATTCCCCTGGCCAGAGTGGAT
TCCTCAGCTATGGCTCCAGCTTCAGCACCTCACCCACTGGACAGAGCCCATACACCTACCAGATGCACGGCACAACAGGGTTCTATCAAG
GAGGAAATGGACTGGGCAACGCAGCCGGTTTCGGGAGTGTGCACCAGGACTATCCTTCCTACCCCGGCTTCCCCCAGAGCCAGTACCCCC
AGTATTACGGCTCATCCTACAACCCTCCCTACGTCCCGGCCAGCAGCATCTGCCCTTCGCCCCTCTCCACGTCCACCTACGTCCTCCAGG
AGGCATCTCACAACGTCCCCAACCAGAGTTCCGAGTCACTTGCTGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGG
GAGACACAGACAGGCCGCACCGGGCCTCCGACGGGAAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATG
AGATTGAGCGTGTGTTCGTGTGGGACTTGGATGAGACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGA
AGATCCTGGGCTTTTCCACCCCTCCAGGCCGGCTCTCCATGATGTCCTTCATCCTCAACGCCCTCACCTGTGCCCTGGGCTTGCTGTACT
TCATCCGGCGAGGAAAGCAGTGTCTGGATTTCACTGTCACTGTCCATTTCTTTCACCTCCTGGGCTGCTGGTTCTACAGCTCCCGTTTCC
CCTCGGCGCTGACCTGGTGGCTGGTCCAAGCCGTGTGCATTGCACTCATGGCTGTCATCGGGGAGTACCTGTGCATGCGGACGGAGCTCA
AGGAGATACCCCTCAACTCAGCCCCTAAATCCAATGTCTAGAATCAGGCCCTTTGGACATCCTGCTGACACTTGGGCCCCTTAACACCTT
GGGCTGCTCAGACCCTCCAGATGAGGTCCAGCCCAGATCTGAGAGGAACC

>28053_28053_10_EYA2-SYS1_EYA2_chr20_45725807_ENST00000357410_SYS1_chr20_43994259_ENST00000372727_length(amino acids)=500AA_BP=398
MRPAAGCVRPRSPASRLGAPTRPRSGAGTRAGAEGGPGPGRRRGRSSRRRQQPRQPRRRRQRQRQRQQRARRSQPGLVGPAPARPPARTA
SGRPLHCARYKEMVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGI
QQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG
FPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSD
PSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKILGFSTPPGRLSMMSFILNALTCALGLLYFIRRGKQCLDFTVTVHFFHLLGC
WFYSSRFPSALTWWLVQAVCIALMAVIGEYLCMRTELKEIPLNSAPKSNV

--------------------------------------------------------------
>28053_28053_11_EYA2-SYS1_EYA2_chr20_45725807_ENST00000357410_SYS1_chr20_43994259_ENST00000414310_length(transcript)=1681nt_BP=1262nt
GCGCGCTCTGCTCGGCTGCAGGCTCAGGAAGCGGCGCGGCGGCACGTGCTGGGCCAGAGCCCCGCGCCCTGCGTCCAGCCGCCGGGTGTG
TGCGCCCGCGTAGCCCAGCGTCGCGCCTCGGCGCCCCCACGCGCCCACGCAGCGGCGCGGGGACCCGGGCGGGGGCAGAGGGAGGGCCCG
GCCCAGGGAGGAGAAGGGGCCGGTCCTCCCGGCGCAGGCAGCAGCCGCGGCAGCCCAGGAGGCGGAGGCAGCGGCAACGGCAGAGACAGC
AACGTGCCCGCCGCAGTCAGCCCGGCCTCGTCGGACCCGCACCGGCCCGCCCGCCCGCCCGCACCGCGTCGGGGCGCCCTCTCCACTGCG
CGCGGTACAAGGAAATGGTAGAACTAGTGATCTCACCCAGCCTCACTGTAAACAGCGATTGTCTGGATAAACTGAAGTTTAACCGTGCTG
ACGCTGCTGTGTGGACTCTGAGTGACAGACAAGGCATCACCAAATCGGCCCCCCTGAGAGTGTCCCAGCTCTTCTCCAGATCTTGCCCAC
GTGTCCTCCCCCGCCAGCCTTCCACAGCCATGGCAGCCTACGGCCAGACGCAGTACAGTGCGGGGATCCAGCAGGCTACCCCCTATACAG
CTTACCCACCTCCAGCACAAGCCTATGGAATCCCTTCCTACAGCATCAAGACAGAAGACAGCTTGAACCATTCCCCTGGCCAGAGTGGAT
TCCTCAGCTATGGCTCCAGCTTCAGCACCTCACCCACTGGACAGAGCCCATACACCTACCAGATGCACGGCACAACAGGGTTCTATCAAG
GAGGAAATGGACTGGGCAACGCAGCCGGTTTCGGGAGTGTGCACCAGGACTATCCTTCCTACCCCGGCTTCCCCCAGAGCCAGTACCCCC
AGTATTACGGCTCATCCTACAACCCTCCCTACGTCCCGGCCAGCAGCATCTGCCCTTCGCCCCTCTCCACGTCCACCTACGTCCTCCAGG
AGGCATCTCACAACGTCCCCAACCAGAGTTCCGAGTCACTTGCTGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGG
GAGACACAGACAGGCCGCACCGGGCCTCCGACGGGAAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATG
AGATTGAGCGTGTGTTCGTGTGGGACTTGGATGAGACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGA
AGATCCTGGGCTTTTCCACCCCTCCAGGCCGGCTCTCCATGATGTCCTTCATCCTCAACGCCCTCACCTGTGCCCTGGGCTTGCTGTACT
TCATCCGGCGAGGAAAGCAGTGTCTGGATTTCACTGTCACTGTCCATTTCTTTCACCTCCTGGGCTGCTGGTTCTACAGCTCCCGTTTCC
CCTCGGCGCTGACCTGGTGGCTGGTCCAAGCCGTGTGCATTGCACTCATGGCTGTCATCGGGGAGTACCTGTGCATGCGGACGGAGCTCA
AGGAGATACCCCTCAACTCAGCCCCTAAATCCAATGTCTAGAATCAGGCCCTTTGGACATCCTGCTGACACTTGGGCCCCTTAACACCTT
GGGCTGCTCAGACCCTCCAGATGAGGTCCAGCCCAGATCTGAGAGGAACCCTGGAAATGTG

>28053_28053_11_EYA2-SYS1_EYA2_chr20_45725807_ENST00000357410_SYS1_chr20_43994259_ENST00000414310_length(amino acids)=500AA_BP=398
MRPAAGCVRPRSPASRLGAPTRPRSGAGTRAGAEGGPGPGRRRGRSSRRRQQPRQPRRRRQRQRQRQQRARRSQPGLVGPAPARPPARTA
SGRPLHCARYKEMVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGI
QQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG
FPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSD
PSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKILGFSTPPGRLSMMSFILNALTCALGLLYFIRRGKQCLDFTVTVHFFHLLGC
WFYSSRFPSALTWWLVQAVCIALMAVIGEYLCMRTELKEIPLNSAPKSNV

--------------------------------------------------------------
>28053_28053_12_EYA2-SYS1_EYA2_chr20_45725807_ENST00000357410_SYS1_chr20_43994259_ENST00000426004_length(transcript)=3835nt_BP=1262nt
GCGCGCTCTGCTCGGCTGCAGGCTCAGGAAGCGGCGCGGCGGCACGTGCTGGGCCAGAGCCCCGCGCCCTGCGTCCAGCCGCCGGGTGTG
TGCGCCCGCGTAGCCCAGCGTCGCGCCTCGGCGCCCCCACGCGCCCACGCAGCGGCGCGGGGACCCGGGCGGGGGCAGAGGGAGGGCCCG
GCCCAGGGAGGAGAAGGGGCCGGTCCTCCCGGCGCAGGCAGCAGCCGCGGCAGCCCAGGAGGCGGAGGCAGCGGCAACGGCAGAGACAGC
AACGTGCCCGCCGCAGTCAGCCCGGCCTCGTCGGACCCGCACCGGCCCGCCCGCCCGCCCGCACCGCGTCGGGGCGCCCTCTCCACTGCG
CGCGGTACAAGGAAATGGTAGAACTAGTGATCTCACCCAGCCTCACTGTAAACAGCGATTGTCTGGATAAACTGAAGTTTAACCGTGCTG
ACGCTGCTGTGTGGACTCTGAGTGACAGACAAGGCATCACCAAATCGGCCCCCCTGAGAGTGTCCCAGCTCTTCTCCAGATCTTGCCCAC
GTGTCCTCCCCCGCCAGCCTTCCACAGCCATGGCAGCCTACGGCCAGACGCAGTACAGTGCGGGGATCCAGCAGGCTACCCCCTATACAG
CTTACCCACCTCCAGCACAAGCCTATGGAATCCCTTCCTACAGCATCAAGACAGAAGACAGCTTGAACCATTCCCCTGGCCAGAGTGGAT
TCCTCAGCTATGGCTCCAGCTTCAGCACCTCACCCACTGGACAGAGCCCATACACCTACCAGATGCACGGCACAACAGGGTTCTATCAAG
GAGGAAATGGACTGGGCAACGCAGCCGGTTTCGGGAGTGTGCACCAGGACTATCCTTCCTACCCCGGCTTCCCCCAGAGCCAGTACCCCC
AGTATTACGGCTCATCCTACAACCCTCCCTACGTCCCGGCCAGCAGCATCTGCCCTTCGCCCCTCTCCACGTCCACCTACGTCCTCCAGG
AGGCATCTCACAACGTCCCCAACCAGAGTTCCGAGTCACTTGCTGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGG
GAGACACAGACAGGCCGCACCGGGCCTCCGACGGGAAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATG
AGATTGAGCGTGTGTTCGTGTGGGACTTGGATGAGACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGA
AGATCCTGGGCTTTTCCACCCCTCCAGGCCGGCTCTCCATGATGTCCTTCATCCTCAACGCCCTCACCTGACAGGGTCTTGCTCTCTTGC
CCAGGCTGGAGTGCAGTGGCGAAGTCACAGCTCACTGCAGCCTCGACTCCTGGGCTTAAGCGATCCTCCGACCTCAGCCTCCTGAGTAGC
TGATACTACAAGCGCAAGGCACCACATCTGGCTAATTTTTAAATTTTTTGTAGAGACAGTGTCTCATTATGTTGCCCAGGATGGTCTTGA
ACTCCTGGCCTCAAGCAGTCTTCCTGCCTCGACCTCCCAAGGTGCTGGGATTACAGGCGTGAGCCACCATGCCTAGCCTGTTCAGAGTAA
ATCTTATTTGAGGCATGAATCAATCAAACATAAATAGAGAGTTGAATTGATCTTAGAGGGAATGGGATGCAGCAAAGCCCTACTTGACCA
TCTCCCCCCTCCCACATTTGGAAATCCTTAAACCCACTTATGTAGGCCTCTGACTGTGAGATTCAGAGCCACAGCAGTTTCCACCTCTGC
TAAGGCCTTCAGGCAGTGAGATGGCTCACTTCAGTGCCCCTCCTTCCACACATCTCCTAGCTGTATCCTGAGACGCCTCAACCTAGTCAC
TACCCTTCTGTATGATGTTGGTCTAAGGCTTCCCCCTCTCTGGACATGAAGGCGGAGCCTCCCAGCACTACCAGCCACACACCACTCAAG
ACTCCAGATCCTGAACCCTGACTCTGGGGCCCAGCTCTGGGCCTGGCTTGGGGCTTGCATCTCACCTAGCCTGGCAGTGTTGTTGTCACA
CCCACCTTGTATGGATGCCACATAGGCATTTCAAGTGATGCGGAGCAGAAGCGGGTGCAGCGGCGCTTGACCCAACGCAGGGTGGAGGAT
CTGCACATCACCCTGGGCGCCGGGAGGTGGATTCGTGTGGGCAGCCCCTCAAACCAGATCCACTGGTCGGCTACATCCAGCTGCTTCATG
TGCCCCATGGGAGTTCTATTGCGGTAGGGCTTAATGAAGATGACTCGGGGGCCCTCGGTGAGTGGTTGCCTCCCCTGGACTCCAGGGTTC
AAGCTATCATCCCTCGATGTCCTTGGAACCTCAGGCTCTATATGCTTTTCTTTCCGTGGCATTGCCGCCAATGACGTTTTCTCCTTGTTC
CTCATCCCTGACTGCACCTGGGACTTCCACTCCTTGTACTCTTTTTTCTTAGGGTCCCCTGTGGACTCTAATTTCTTGGACTTGAGTTCC
TTCTCGGAGCACCCGATCTCCTGGAACTCTTCATTATTTTGTTTTGTTTTATTGCAGGCACTGTTTTCCCTGGCAGGGAGAGGAAAGGCA
GTCAGCACAGCAGGACCGAGGCCCTGGTTCCCGAGACAGTTGCTATGTAGCCAGCTCAGGGGAGCCTGTTAAGAAAGGCTAGAGGGGCCT
GCAAAGAAACTTCTCTACTGCCCAGAGGCCTTGTGCTGGTGTGAGGAGGTGTGATGAGCACTAGCAGAGGGATGTGAGAGATTGGGAAGG
TGAAAGCCATGACTAGTAGTTAAGGCCCCTAAGAATGAATATTGTCTACATCATCTGCCACTAGATTAGGGTTCTGTCTCTCTGGACTTC
AGCTGGGAGGGTGAACAGTCCAGTAGTTTTTCTAAATTGTGCTCCAAGAACCTTAGGGTTCTGAGGAGGTGTCTCAATGTCACCTCCCCT
GACCCACTGGGGCAGGATACCTCTCCCCAGCTCATAACAACACAATTGGGGCTTGGAAATAGATATTTGAACAGAGGTTTCACTGCTTTA
ATAAAGTTGGAAAACTGTTCAAGACCAGCCTGGGCAACATGGTGAGACTCTGTCTCCATACAAAAAAAAAATTTTTAAGTTGGAAAATGA
TGGGGCTAGATGATCCTGATCCTTCTAGCTCTATGTTTCCTGATTGCCTGCGACTAGAGGCCAAATCAGAAAGAGGAGCCCAGAAAGGTG
GCCTTGACAGAAATATTAAATGCTGAGACTTTCCCAAAGGGTGTCTGTAACAGACTGGGCCCCCTGCAAACCCCCAGTGGCAACACCATC
CTAGCCAAGGGCGTGGAGAGAGATGAGGCCTTGGGCTGCAGATAATGGCAATACTGTGATGATAATAATGGCTCCCGCTGATTGAGTCCT
CGCTCTATGCCAGACTCGGGACCCTTACAACTTGGGATCCTTACTATTTCTGTGAAGTAGAAGGCAGTGAAACAGAGTGGCTTACAGAGC
ACAGGTGTTGGATTCAGACAAACGGGCTCAGATTCTGCTTCTGCCTCTTACCACCTGTGTGATTTGGGCAAGATATTTAACCTCTCAGAG
CCTTAGCTTCCTTATCTGTAAAACTAGGATAATTCTGTCTACCTAACAGGATTGTTGTGAAGAATAAACTAAATGGGAAAATTCTTAAGT
GCTTAACACTGTAGGATGGTACTTAGCAGGCACCAATCAATGTTAGCTTTCTTAATACTGTCATGTGACTTATGAGGAAACGGTTTGAAC
TTGTCTCGGAGGCATGGTAAAAAAAAATAAAAATAAAAATAAATTAATAAAGAAA

>28053_28053_12_EYA2-SYS1_EYA2_chr20_45725807_ENST00000357410_SYS1_chr20_43994259_ENST00000426004_length(amino acids)=420AA_BP=398
MRPAAGCVRPRSPASRLGAPTRPRSGAGTRAGAEGGPGPGRRRGRSSRRRQQPRQPRRRRQRQRQRQQRARRSQPGLVGPAPARPPARTA
SGRPLHCARYKEMVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGI
QQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG
FPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSD
PSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKILGFSTPPGRLSMMSFILNALT

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Fusion Gene PPI Analysis for EYA2-SYS1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EYA2-SYS1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for EYA2-SYS1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource