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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:FDFT1-TNKS (FusionGDB2 ID:HG2222TG8658) |
Fusion Gene Summary for FDFT1-TNKS |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FDFT1-TNKS | Fusion gene ID: hg2222tg8658 | Hgene | Tgene | Gene symbol | FDFT1 | TNKS | Gene ID | 2222 | 8658 |
| Gene name | farnesyl-diphosphate farnesyltransferase 1 | tankyrase | |
| Synonyms | DGPT|ERG9|SQS|SQSD|SS | ARTD5|PARP-5a|PARP5A|PARPL|TIN1|TINF1|TNKS1|pART5 | |
| Cytomap | ('FDFT1')('TNKS') 8p23.1 | 8p23.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | squalene synthaseFPP:FPP farnesyltransferasepresqualene-di-diphosphate synthasesqualene synthetase | poly [ADP-ribose] polymerase tankyrase-1ADP-ribosyltransferase diphtheria toxin-like 5TANK1TNKS-1TRF1-interacting ankyrin-related ADP-ribose polymerase 1poly [ADP-ribose] polymerase 5Aprotein poly-ADP-ribosyltransferase tankyrase-1tankyrase Itanky | |
| Modification date | 20200320 | 20200313 | |
| UniProtAcc | P37268 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000220584, ENST00000443614, ENST00000446331, ENST00000525777, ENST00000525900, ENST00000528643, ENST00000528812, ENST00000530664, ENST00000538689, | ||
| Fusion gene scores | * DoF score | 16 X 12 X 9=1728 | 8 X 9 X 6=432 |
| # samples | 20 | 9 | |
| ** MAII score | log2(20/1728*10)=-3.11103131238874 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/432*10)=-2.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: FDFT1 [Title/Abstract] AND TNKS [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | FDFT1(11660440)-TNKS(9562173), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | FDFT1-TNKS seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. FDFT1-TNKS seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. FDFT1-TNKS seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. FDFT1-TNKS seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | TNKS | GO:0000209 | protein polyubiquitination | 19759537|21478859 |
| Tgene | TNKS | GO:0006471 | protein ADP-ribosylation | 9822378|15133513|21270334 |
| Tgene | TNKS | GO:0018105 | peptidyl-serine phosphorylation | 17026964 |
| Tgene | TNKS | GO:0018107 | peptidyl-threonine phosphorylation | 17026964 |
| Tgene | TNKS | GO:0032212 | positive regulation of telomere maintenance via telomerase | 12782650|18221737 |
| Tgene | TNKS | GO:0045944 | positive regulation of transcription by RNA polymerase II | 19245366 |
| Tgene | TNKS | GO:0051973 | positive regulation of telomerase activity | 12782650 |
| Tgene | TNKS | GO:0070212 | protein poly-ADP-ribosylation | 9822378|16076287|25043379 |
| Tgene | TNKS | GO:0070213 | protein auto-ADP-ribosylation | 9822378|15133513|19759537|21478859 |
| Tgene | TNKS | GO:1904355 | positive regulation of telomere capping | 21531765 |
| Tgene | TNKS | GO:1904743 | negative regulation of telomeric DNA binding | 9822378 |
| Fusion gene breakpoints across FDFT1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across TNKS (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BLCA | TCGA-GC-A4ZW-01A | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
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Fusion Gene ORF analysis for FDFT1-TNKS |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-3UTR | ENST00000220584 | ENST00000518027 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| 5CDS-3UTR | ENST00000443614 | ENST00000518027 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| 5CDS-intron | ENST00000220584 | ENST00000522110 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| 5CDS-intron | ENST00000443614 | ENST00000522110 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| In-frame | ENST00000220584 | ENST00000310430 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| In-frame | ENST00000220584 | ENST00000518281 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| In-frame | ENST00000220584 | ENST00000520408 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| In-frame | ENST00000443614 | ENST00000310430 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| In-frame | ENST00000443614 | ENST00000518281 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| In-frame | ENST00000443614 | ENST00000520408 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000446331 | ENST00000310430 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000446331 | ENST00000518281 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000446331 | ENST00000520408 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000525777 | ENST00000310430 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000525777 | ENST00000518281 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000525777 | ENST00000520408 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000525900 | ENST00000310430 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000525900 | ENST00000518281 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000525900 | ENST00000520408 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000528643 | ENST00000310430 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000528643 | ENST00000518281 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000528643 | ENST00000520408 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000528812 | ENST00000310430 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000528812 | ENST00000518281 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000528812 | ENST00000520408 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000530664 | ENST00000310430 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000530664 | ENST00000518281 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000530664 | ENST00000520408 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000538689 | ENST00000310430 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000538689 | ENST00000518281 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3CDS | ENST00000538689 | ENST00000520408 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3UTR | ENST00000446331 | ENST00000518027 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3UTR | ENST00000525777 | ENST00000518027 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3UTR | ENST00000525900 | ENST00000518027 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3UTR | ENST00000528643 | ENST00000518027 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3UTR | ENST00000528812 | ENST00000518027 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3UTR | ENST00000530664 | ENST00000518027 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-3UTR | ENST00000538689 | ENST00000518027 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-intron | ENST00000446331 | ENST00000522110 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-intron | ENST00000525777 | ENST00000522110 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-intron | ENST00000525900 | ENST00000522110 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-intron | ENST00000528643 | ENST00000522110 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-intron | ENST00000528812 | ENST00000522110 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-intron | ENST00000530664 | ENST00000522110 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| intron-intron | ENST00000538689 | ENST00000522110 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000220584 | FDFT1 | chr8 | 11660440 | + | ENST00000520408 | TNKS | chr8 | 9562173 | + | 1152 | 321 | 222 | 1067 | 281 |
| ENST00000220584 | FDFT1 | chr8 | 11660440 | + | ENST00000310430 | TNKS | chr8 | 9562173 | + | 8808 | 321 | 222 | 3197 | 991 |
| ENST00000220584 | FDFT1 | chr8 | 11660440 | + | ENST00000518281 | TNKS | chr8 | 9562173 | + | 3391 | 321 | 222 | 3197 | 991 |
| ENST00000443614 | FDFT1 | chr8 | 11660440 | + | ENST00000520408 | TNKS | chr8 | 9562173 | + | 1024 | 193 | 94 | 939 | 281 |
| ENST00000443614 | FDFT1 | chr8 | 11660440 | + | ENST00000310430 | TNKS | chr8 | 9562173 | + | 8680 | 193 | 94 | 3069 | 991 |
| ENST00000443614 | FDFT1 | chr8 | 11660440 | + | ENST00000518281 | TNKS | chr8 | 9562173 | + | 3263 | 193 | 94 | 3069 | 991 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000220584 | ENST00000520408 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + | 0.003045551 | 0.99695444 |
| ENST00000220584 | ENST00000310430 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + | 0.000251723 | 0.9997483 |
| ENST00000220584 | ENST00000518281 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + | 0.002204993 | 0.997795 |
| ENST00000443614 | ENST00000520408 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + | 0.001958652 | 0.9980413 |
| ENST00000443614 | ENST00000310430 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + | 0.000208535 | 0.99979144 |
| ENST00000443614 | ENST00000518281 | FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562173 | + | 0.001738184 | 0.99826187 |
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Fusion Genomic Features for FDFT1-TNKS |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562172 | + | 1.25E-08 | 1 |
| FDFT1 | chr8 | 11660440 | + | TNKS | chr8 | 9562172 | + | 1.25E-08 | 1 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for FDFT1-TNKS |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:11660440/chr8:9562173) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FDFT1 | . |
| FUNCTION: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene. Proceeds in two distinct steps. In the first half-reaction, two molecules of FPP react to form the stable presqualene diphosphate intermediate (PSQPP), with concomitant release of a proton and a molecule of inorganic diphosphate. In the second half-reaction, PSQPP undergoes heterolysis, isomerization, and reduction with NADPH or NADH to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway. {ECO:0000269|PubMed:10896663, ECO:0000269|PubMed:24531458}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 1030_1089 | 369 | 1328.0 | Domain | SAM | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 1112_1317 | 369 | 1328.0 | Domain | PARP catalytic | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 368_397 | 369 | 1328.0 | Repeat | ANK 6 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 401_430 | 369 | 1328.0 | Repeat | ANK 7 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 434_463 | 369 | 1328.0 | Repeat | ANK 8 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 521_553 | 369 | 1328.0 | Repeat | ANK 9 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 557_586 | 369 | 1328.0 | Repeat | ANK 10 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 590_619 | 369 | 1328.0 | Repeat | ANK 11 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 621_647 | 369 | 1328.0 | Repeat | ANK 12 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 649_679 | 369 | 1328.0 | Repeat | ANK 13 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 683_712 | 369 | 1328.0 | Repeat | ANK 14 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 716_745 | 369 | 1328.0 | Repeat | ANK 15 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 749_778 | 369 | 1328.0 | Repeat | ANK 16 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 782_810 | 369 | 1328.0 | Repeat | ANK 17 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 836_865 | 369 | 1328.0 | Repeat | ANK 18 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 869_898 | 369 | 1328.0 | Repeat | ANK 19 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 902_931 | 369 | 1328.0 | Repeat | ANK 20 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 935_964 | 369 | 1328.0 | Repeat | ANK 21 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | FDFT1 | chr8:11660440 | chr8:9562173 | ENST00000220584 | + | 1 | 8 | 284_304 | 33 | 418.0 | Transmembrane | Helical |
| Hgene | FDFT1 | chr8:11660440 | chr8:9562173 | ENST00000220584 | + | 1 | 8 | 384_404 | 33 | 418.0 | Transmembrane | Helical |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 109_161 | 369 | 1328.0 | Compositional bias | Ser-rich | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 20_83 | 369 | 1328.0 | Compositional bias | Pro-rich | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 9_14 | 369 | 1328.0 | Compositional bias | Poly-His | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 181_209 | 369 | 1328.0 | Repeat | ANK 1 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 215_244 | 369 | 1328.0 | Repeat | ANK 2 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 248_277 | 369 | 1328.0 | Repeat | ANK 3 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 281_310 | 369 | 1328.0 | Repeat | ANK 4 | |
| Tgene | TNKS | chr8:11660440 | chr8:9562173 | ENST00000310430 | 4 | 27 | 335_364 | 369 | 1328.0 | Repeat | ANK 5 |
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Fusion Gene Sequence for FDFT1-TNKS |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >30051_30051_1_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000220584_TNKS_chr8_9562173_ENST00000310430_length(transcript)=8808nt_BP=321nt AATCAGCGCCCGTCAGCCCACCCCACGAGGCCGCAGCTAGCCCCGCTGGCGGCCGAGGCCGGTTGAAGTGGGCGGAGCGGCGGGCGGGGC GTCGCCGTACTAGGCCTGCCCCCTGTCCGGCCAGCCCCTCGAAGCACCTACTCCACAGGTCCAGCCGGCCGGTGAGCGCCTGGGGACCGC AGAGGTGAGAGTCGCGCCCGGGAGTCCGCCGCCTGCGCCAGGATGGAGTTCGTGAAATGCCTTGGCCACCCCGAAGAGTTCTACAACCTG GTGCGCTTCCGGATCGGGGGCAAGCGGAAGGTGATGCCCAAGATGGACCAGTCGACTCCTTTACATCTAGCAGCGGGCTACAACAGAGTT CGAATAGTTCAGCTTCTTCTTCAGCATGGTGCTGATGTTCATGCAAAAGACAAAGGTGGACTTGTGCCTCTTCATAATGCATGTTCATAT GGACATTATGAAGTCACAGAACTGCTACTAAAGCATGGAGCTTGTGTTAATGCCATGGATCTCTGGCAGTTTACTCCACTGCACGAGGCT GCTTCCAAGAACCGTGTAGAAGTCTGCTCTTTGTTACTTAGCCATGGCGCTGATCCTACATTAGTCAACTGCCATGGCAAAAGTGCTGTG GATATGGCTCCAACTCCGGAGCTTAGGGAGAGATTGACTTATGAATTTAAAGGTCATTCTTTACTACAAGCAGCCAGAGAAGCAGACTTA GCTAAAGTTAAAAAAACACTCGCTCTGGAAATCATTAATTTCAAACAACCGCAGTCTCATGAAACAGCACTGCACTGTGCTGTGGCCTCT CTGCATCCCAAACGTAAACAAGTGACAGAATTGTTACTTAGAAAAGGAGCAAATGTTAATGAAAAAAATAAAGATTTCATGACTCCCCTG CATGTTGCAGCCGAAAGAGCCCATAATGATGTCATGGAAGTTCTGCATAAGCATGGCGCCAAGATGAATGCACTGGACACCCTTGGTCAG ACTGCTTTGCATAGAGCCGCCCTAGCAGGTCACCTGCAGACCTGCCGCCTCCTGCTGAGTTACGGCTCTGACCCCTCCATCATCTCCTTA CAAGGCTTCACAGCAGCACAGATGGGCAATGAAGCAGTGCAGCAGATTCTGAGTGAGAGTACACCTATACGTACTTCTGATGTTGATTAT CGACTCTTAGAGGCATCTAAAGCTGGAGACTTGGAAACTGTGAAGCAACTTTGCAGCTCTCAAAATGTGAATTGTAGAGACTTAGAGGGC CGGCATTCCACGCCCTTACACTTCGCAGCAGGCTACAACCGCGTGTCTGTTGTAGAGTACCTGCTACACCACGGTGCCGATGTCCATGCC AAAGACAAGGGTGGCTTGGTGCCCCTTCATAATGCCTGTTCATATGGACACTATGAGGTGGCTGAGCTTTTAGTAAGGCATGGGGCTTCT GTCAATGTGGCGGACTTATGGAAATTTACCCCTCTCCATGAAGCAGCAGCTAAAGGAAAGTATGAAATCTGCAAGCTCCTTTTAAAACAT GGAGCAGATCCAACTAAAAAGAACAGAGATGGAAATACACCTTTGGATTTGGTAAAGGAAGGAGACACAGATATTCAGGACTTACTGAGA GGGGATGCTGCTTTGTTGGATGCTGCCAAGAAGGGCTGCCTGGCAAGAGTGCAGAAGCTCTGTACCCCAGAGAATATCAACTGCAGAGAC ACCCAGGGCAGAAATTCAACCCCTCTGCACCTGGCAGCAGGCTATAATAACCTGGAAGTAGCTGAATATCTTCTAGAGCATGGAGCTGAT GTTAATGCCCAGGACAAGGGTGGTTTAATTCCTCTTCATAATGCGGCATCTTATGGGCATGTTGACATAGCGGCTTTATTGATAAAATAC AACACGTGTGTAAATGCAACAGATAAGTGGGCGTTTACTCCCCTCCATGAAGCAGCCCAGAAAGGAAGGACGCAGCTGTGCGCCCTCCTC CTAGCGCATGGTGCAGACCCCACCATGAAGAACCAGGAAGGCCAGACGCCTCTGGATCTGGCAACAGCTGACGATATCAGAGCTTTGCTG ATAGATGCCATGCCCCCAGAGGCCTTACCTACCTGTTTTAAACCTCAGGCTACTGTAGTGAGTGCCTCTCTGATCTCACCAGCATCCACC CCCTCCTGCCTCTCGGCTGCCAGCAGCATAGACAACCTCACTGGCCCTTTAGCAGAGTTGGCCGTAGGAGGAGCCTCCAATGCAGGGGAT GGCGCCGCGGGAACAGAAAGGAAGGAAGGAGAAGTTGCTGGTCTTGACATGAATATCAGCCAATTTCTAAAAAGCCTTGGCCTTGAACAC CTTCGGGATATCTTTGAAACAGAACAGATTACACTAGATGTGTTGGCTGATATGGGTCATGAAGAGTTGAAAGAAATAGGCATCAATGCA TATGGGCACCGCCACAAATTAATCAAAGGAGTAGAAAGACTCTTAGGTGGACAACAAGGCACCAATCCTTATTTGACTTTTCACTGTGTT AATCAGGGAACGATTTTGCTGGATCTTGCTCCAGAAGATAAAGAATATCAGTCAGTGGAAGAAGAGATGCAAAGTACTATTCGAGAACAC AGAGATGGTGGTAATGCTGGCGGCATCTTCAACAGATACAATGTCATTCGAATTCAAAAAGTTGTCAACAAGAAGTTGAGGGAGCGGTTC TGCCACCGACAGAAGGAAGTGTCTGAGGAGAATCACAACCATCACAATGAGCGCATGTTGTTTCATGGTTCTCCTTTCATTAATGCCATT ATTCATAAAGGGTTTGATGAGCGACATGCATACATAGGAGGAATGTTTGGGGCCGGGATTTATTTTGCTGAAAACTCCTCAAAAAGCAAC CAATATGTTTATGGAATTGGAGGAGGAACAGGCTGCCCTACACACAAGGACAGGTCATGCTATATATGTCACAGACAAATGCTCTTCTGT AGAGTGACCCTTGGGAAATCCTTTCTGCAGTTTAGCACCATGAAAATGGCCCACGCGCCTCCAGGGCACCACTCAGTCATTGGTAGACCG AGCGTCAATGGGCTGGCATATGCTGAATATGTCATCTACAGAGGAGAACAGGCATACCCAGAGTATCTTATCACTTACCAGATCATGAAG CCAGAAGCCCCTTCCCAGACCGCAACAGCCGCAGAGCAGAAGACCTAGTGAATGCCTGCTGGTGAAGGCCAGATCAGATTTCAACCTGGG ACTGGATTACAGAGGATTGTTTCTAATAACAACATCAATATTCTAGAAGTCCCTGACAGCCTAGAAATAAGCTGTTTGTCTTCTATAAAG CATTGCTATAGTGATGAATAGTATGAGTAACTGATACATACTCAACTGCTACTGTTCCCTTTGAGGAAATGTTTACAGGGGCGGCCTTTT AACATATCTCAGGCTCATTTTCATTGCAATTATCCATTTCTAAAACAAGATTGCTTCGATCTAGACTTGGAAATGGAAAATAAGAAAACC AATGCTTTTTCAAATGTTCACAATTCACACACTACATTTGTTTTGTTATGCATGACGTGTCTATAACAAATATACACATACGACAGGCAA CAAGCTTGTTTTTGATTTGCCAGACATGCATCATTGGCTATTGTTTGTTTGTTTTTTGTTTTTTTGTGTTTTTTGGGTTACTTTGAAAAT GAGCCAGAGCCTTCTTGAGGATATTTTGCACAAAGTCACGCTGACAAAATCATTAGCAGTGCAACCCAAGCTTCTGGCTGAGCAAGATTC AGTTTCCACTTTTTAAAATTTTTTTATTTTGCTCTGTAGCTGCACTTCTCGTTATCATAAATTGAGATGAAAAGGAAAAAACATCAAGTT TTAGTACCTTTTTATGAATTGGCCTATCTTACAAGAGAAGGGCACAAACACCAACCTGACTTAGGAACGCCTAAATTCAGAGAAGTCAAA GCCGGTGAAGGCCACTTGCTCTTTCCAACACAAGCCTGCCACAGAGGTCTTCGGGACAGTACTGGAGATGCAGGTTGACACGGGCTTGAG TTCCAAGGTGAAAAAACTGGGGAGGCTGTGAAGGAAGAGCTGCATTAAGGAGGGTGAGGAGCGTGTGGTTCTGTATCATGGCAGCCCCAA TGGATCCAGGGGATGCCTCCAAAAAATACATGCTTCCCTTCCCTTAATCTGTACTGTTGGGATTGTTACCCCTCCAAATTAGCTGCCTTA TTTCAAAAGTCAGTGAAATTACTGCACTTGATGAGGGTCACAAAAATACCACTTGATTGTTTCTTTAGTTGAGAATGCTGGGATTCAGAC TCGAATAGTGGATAGATACACACAAATGCAAGGACTTTTTTGTTTACTCCAGATTTGGGGTTTATTTTGAGTGGCATGCTTCAAATAGTT CATAAAGATCCTTGCATTAAATTTCTGAACCATTTCTTCAAACTTCTTAGTGTGTTTAGACAAGGAGAACAAAAATTGAAACCAAAGCCC TTTCTGTTATTTTTTCAATGAAGGTGAGAAAGAAATACCATACAATTTTCTTTGTGAAATTACTGTTTATTTTCATCAACATTTACCAAG TGCCATTGACATTTATAAAAAAAAATGATCCTTTATAGTTCTTACACTTGCCCTTTTCACCTTAACTGAATATGAATTGAGTGCACTAAC TTATTTACTTGATATACTGTGCATCTACTCTGCTTTGAAGCGAAAGAAATATAAACACGAGGAGGAATAGGAAAGACAGTGTGACACAAA CTTGCCATTGCAATTCAAAGCCCTGAAAACGATGGGTTTAATGCAAGGTGATTAAGCTGTGACCTCCTTTAATCTCCTGAAGCAAAATAA AATGGTTACATGCAAAACTTCTAGAAATAGACTCTTAAAATATATACATTTTGCTTTGATTTTGGCTTCAACCCAGTGCTGGAACTAGGC ATCCAGACTAGTTTGAATGTTTGTAGCTGAATTTTTATGGGTCCTCAAAATTAAATCGAGAATTAGCCTCAGTTGTTGCTTCTTTTGAAG TTTCAGTGACCCAAGCTGGGTGTTTGTGTCTTGGCTACTTGTTTAATAGCACTAGAATTCCAGGTGAAGCTTTGAGAGTTGATATTCATT AAGAGGGCTTTTTTTCCCCTTCTTTCCTTCTCTTTTGCTGTAACAAAGGGTTGAAGAAATTGCCATCTGTGTAGTTTTCAGTAGCTGTCA AGTGTGTCTTACTTACCTTCCCCCAGACGTAGTTTAAAATGGTAAACACAGCTGTGATTTTTAGTTAAGTAAAAGAGTTAATATGATATA GATATGGAAAGCTTTATGGCTTCATTAAAAAGATAAACCACTACCTAACTGTGGTTGTATGTTGTTTCCATCATACTAACTAGATGAATG GATGCGCCAGTTTTCATCTTGGTCCTTACACTTGAGAAGTTAAACTGTGGTTCAGTATTTAAACTGCCAGTGTTATACGTCTCATGCTCT GTGTGCCAGGTGAAGGTACTGTGTAAGGAAGACATTTGCGGTGCTTCTTGTCCTATAATGATTCAAGTATATAGTAGTTCTTGAAAGAGT GTGCATATATTACTCATCTGCTTAAGAGAGTGGGTTAATGGATATATCAGAGGAGCCAAATACATTTTTTTCAGAACTTGAAAACCAAAG GTCATCATGAGTGCACTCAAAAGTTAGGACAAGTTTATTACATTTGGGATTTTCATCTGTAGCCGTATGAAGAACCCTTTCCAATATAAA AGCATGGCATTAAATTAGGCTGAAGTCTTTTATTTTTTGTATATGTACTATATAGAAATACTAGCAAGTTAGGATCATCCAATATGGCCT ACCCCGAAATGGCCCCTCTGTTTCCCTAACCACATGGAAGAAAGAATCTGAACGTCTCCACCGGCTCTACCCGAGTTCCAAAACTAAAGG GCTTCTCCAGACCTGATGGTTCCAGTTTACCTGCTGTTGGCCTGCTGGATACTTGACTCAGGCATAAATTAAGTGCCCTGGTCCCGAACT TTCTCCCTGTATTTGACCTCCTTCCCTCTTTCCTAAATTACTAGTCTGGAATTAAAATTAGCTCCAGCAATGACCTTTGACTCCATTCAT TTTCTCCTCATCTTGGGTCTTAAAAAAGGAGACCAGATACCTCCTAGCTTTTGTATCACAACCAGGAATGGGTATTAGGCCTCATGCGCT TTGCTCAGAACACTGCCGCTTTGTTAACAAATGACAGCATGGAACCCAGAGTTTTGATTCGATGCAAAATAACAGCAGTGCAACCAGGAT TCTTGTTTTCCTTTTCCTTCTTGGAGTTTGGAATTTCTAGCTTTTCAAGCAGCATAAGTAGAATCAACATTAGGATGTTTTCATGAAATA GCATCCTTATACTTCTTTGAGCTTGATGTTAGTGGCTAGACTGATTTCCCTTTGCTCTCAAAATACAAAGTGCATTGAAGTATACAGAGA AATGCCTGAATATGGCAAGCAAATAATGTAGATTAACATTCTATTATTGTATCCGTTTTACAAAAAATAAAATTTTGATATATGCCGGAG AACGGCATTAGAATGCAATAAGTTGTCTAGGTTTTTCTGTTTCAGTGTCTCTCCCAATGGCACGAAGGGTTATTGGGCATTGTCCCCACC CCCGCCTTTTTAACATGTGCACTATCTGGATTCCTGTAAATGGCCTTGCAAACAGAAGTGGTGTGTATTTTCAAGCACCTTTCCCCCATT GTATCCGAATCCCTCTTGTGTGATATCTGTGACAAATAGCCTTCTTCTTGTGTTTTCTGTTGGACTAATTGTCTCACGTAAAGCTATAGA CCTTACTAATTTGGCAGGTATTCAAAACTGCCATTAAGATAGGATTTCATGTCAGATACGTATTTAAAGAGTAAAGTCAAATTTGTTTAA TGTCAGATCAGTGACAGAAGTGAAAAGAAAGTAATTGTGAAAGTGATGTTTGAGCTATTGTACACATCTAGCATATGGAAAGCAAATGCA CTCGAAAACTACTATTCTAGAACATGAGGCTTCTTCAGCAACTTGTGCACTCTGCCATTAATAAATTAAATTTTTCCCCTCTAGAAAGCC TTAACTATGGCGGAAACTTTTTAACCTTTTATATTTTAATAAATAAAACATTGTAGTCCCATTTCTTAGTGTTTGAAAGGTGTGTCAGTG AGTCGGCCATGTCTCCATGTGTTTCAGACCTGTTCATCTTATTTTATGATGGTATATTTCATAAGTAATATTCCCTTACATGCAATGGAG CTGATTAAAATTAATCCATTTCAATTTCTCCATATTGGAACTTCCTCAGCTACCAGATTTCTGGTTTGGAGAAGTGCTGGAAAGATTTCA AAGCCTATTCAGTTGTGTATGTGGGGATACGACAGCAACTGTGATACCTTGTAGAATATGAGTGATATGCAAGCTGTGTTTTTTAATTGT TTTAAAATGTAAATTATGGTTATGCTAAAGTGAAAACCTAGAGGAAGCTAATGATTTTATATACTTTGCACGACCAAATATGGTCGTAGT ATGACGAGTTTTATACATTGCCAGAGAGTTCTGCCTCCTCTGAAATAACATTCGCACTGTAGATTGCATTTCGGCTTTTCCTCCTTTCAC ATTCTTTTTTGCTTTACACTTCACGTCTTCGCACCTGCCCTACCTCCCATCCTTTCAAAGAGGTTTCTTTCACGTTCCAGAATTCAGATT GTTCTGTGATTTCTTTTACATCAGTCTACCCATTTCTGCAGGCAGCCCTGAAAGCCCTTGTGTTGATTCAGAGTGTTTGCAGAGAAATGC AGTTGAACCCTGGTAGTGGGGTGTCCCTCACACACCCGCGCACCCCTCCCAAAGTTCAGGATGAAAGGCTAGAAAACCCATTCAAAGTTA GGAAAGAACACAGATCTTTGAGGCCGATAGCCTAGACCTAGAAGATGACCTTGAGTATGTAAACATTGTCTCCGTGACACAAAACACTGA AACTCTTCATGTGCATATAACACCTGCTTCTGCTCCCATTGTTTCAAGCTCATCTTATCTTTGTAGTAGTAATGTTTGTCTTTGATACCT ACAAACTAAAAAGGTACTTTTATCAAGGTTTCTCAAAACATTTACAAAACCAGCTTTGAGAAAATGTTATGTTGCCTGGCAACAGCACTC GGAGTAGTAATTGTGTTTTCTCATTGTGATGTTGGTCTGTGTGAGCAACCAGTGTAGTGACTCTTTGGTTCATTATTCGTGTTGTTTTTA TTTTTAGTCTCTGTGTGACCCAACAGTGGCAGGGGTTACAACCCCCTCTCCTTTCTTTTTTGTATTTATCTATTTGTAGGATTGTCAGAT CAAGTACAAGATGCCCAGTTAAGTTTGAATTTCAGAGAAACAATTTCACGTTAAGAATGTTTCATGCAATATTTGGCATATATTTACAGT AAAAGCATTCATTATTTGTCTGAAATTCAAATTTAACTGAGCATGCTGGTTTTTCTCATTGTTTGGTTTTTCTAAATCTGGCAATCCTAC AGCTGTGGTCATGGGAAATCACCTACAGCATGTTAAAGTCCTCTAGTCATCATCTCGTCACCTGAAATGGAAGTCCTTTTTCCCTCACCC TCCACTTCTTTCCAAAGGAGGGCATCAAGGAACTTAACCTGCCTGCCTGGTGGGTTTCTATTTAAGACATCTTTGTGATTATATTTAACC >30051_30051_1_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000220584_TNKS_chr8_9562173_ENST00000310430_length(amino acids)=991AA_BP=317 MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA CVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINF KQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQT CRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNR VSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTP LDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHN AASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDAMPPEALPTCFK PQATVVSASLISPASTPSCLSAASSIDNLTGPLAELAVGGASNAGDGAAGTERKEGEVAGLDMNISQFLKSLGLEHLRDIFETEQITLDV LADMGHEELKEIGINAYGHRHKLIKGVERLLGGQQGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYN VIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPT HKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTATAAEQK -------------------------------------------------------------- >30051_30051_2_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000220584_TNKS_chr8_9562173_ENST00000518281_length(transcript)=3391nt_BP=321nt AATCAGCGCCCGTCAGCCCACCCCACGAGGCCGCAGCTAGCCCCGCTGGCGGCCGAGGCCGGTTGAAGTGGGCGGAGCGGCGGGCGGGGC GTCGCCGTACTAGGCCTGCCCCCTGTCCGGCCAGCCCCTCGAAGCACCTACTCCACAGGTCCAGCCGGCCGGTGAGCGCCTGGGGACCGC AGAGGTGAGAGTCGCGCCCGGGAGTCCGCCGCCTGCGCCAGGATGGAGTTCGTGAAATGCCTTGGCCACCCCGAAGAGTTCTACAACCTG GTGCGCTTCCGGATCGGGGGCAAGCGGAAGGTGATGCCCAAGATGGACCAGTCGACTCCTTTACATCTAGCAGCGGGCTACAACAGAGTT CGAATAGTTCAGCTTCTTCTTCAGCATGGTGCTGATGTTCATGCAAAAGACAAAGGTGGACTTGTGCCTCTTCATAATGCATGTTCATAT GGACATTATGAAGTCACAGAACTGCTACTAAAGCATGGAGCTTGTGTTAATGCCATGGATCTCTGGCAGTTTACTCCACTGCACGAGGCT GCTTCCAAGAACCGTGTAGAAGTCTGCTCTTTGTTACTTAGCCATGGCGCTGATCCTACATTAGTCAACTGCCATGGCAAAAGTGCTGTG GATATGGCTCCAACTCCGGAGCTTAGGGAGAGATTGACTTATGAATTTAAAGGTCATTCTTTACTACAAGCAGCCAGAGAAGCAGACTTA GCTAAAGTTAAAAAAACACTCGCTCTGGAAATCATTAATTTCAAACAACCGCAGTCTCATGAAACAGCACTGCACTGTGCTGTGGCCTCT CTGCATCCCAAACGTAAACAAGTGACAGAATTGTTACTTAGAAAAGGAGCAAATGTTAATGAAAAAAATAAAGATTTCATGACTCCCCTG CATGTTGCAGCCGAAAGAGCCCATAATGATGTCATGGAAGTTCTGCATAAGCATGGCGCCAAGATGAATGCACTGGACACCCTTGGTCAG ACTGCTTTGCATAGAGCCGCCCTAGCAGGTCACCTGCAGACCTGCCGCCTCCTGCTGAGTTACGGCTCTGACCCCTCCATCATCTCCTTA CAAGGCTTCACAGCAGCACAGATGGGCAATGAAGCAGTGCAGCAGATTCTGAGTGAGAGTACACCTATACGTACTTCTGATGTTGATTAT CGACTCTTAGAGGCATCTAAAGCTGGAGACTTGGAAACTGTGAAGCAACTTTGCAGCTCTCAAAATGTGAATTGTAGAGACTTAGAGGGC CGGCATTCCACGCCCTTACACTTCGCAGCAGGCTACAACCGCGTGTCTGTTGTAGAGTACCTGCTACACCACGGTGCCGATGTCCATGCC AAAGACAAGGGTGGCTTGGTGCCCCTTCATAATGCCTGTTCATATGGACACTATGAGGTGGCTGAGCTTTTAGTAAGGCATGGGGCTTCT GTCAATGTGGCGGACTTATGGAAATTTACCCCTCTCCATGAAGCAGCAGCTAAAGGAAAGTATGAAATCTGCAAGCTCCTTTTAAAACAT GGAGCAGATCCAACTAAAAAGAACAGAGATGGAAATACACCTTTGGATTTGGTAAAGGAAGGAGACACAGATATTCAGGACTTACTGAGA GGGGATGCTGCTTTGTTGGATGCTGCCAAGAAGGGCTGCCTGGCAAGAGTGCAGAAGCTCTGTACCCCAGAGAATATCAACTGCAGAGAC ACCCAGGGCAGAAATTCAACCCCTCTGCACCTGGCAGCAGGCTATAATAACCTGGAAGTAGCTGAATATCTTCTAGAGCATGGAGCTGAT GTTAATGCCCAGGACAAGGGTGGTTTAATTCCTCTTCATAATGCGGCATCTTATGGGCATGTTGACATAGCGGCTTTATTGATAAAATAC AACACGTGTGTAAATGCAACAGATAAGTGGGCGTTTACTCCCCTCCATGAAGCAGCCCAGAAAGGAAGGACGCAGCTGTGCGCCCTCCTC CTAGCGCATGGTGCAGACCCCACCATGAAGAACCAGGAAGGCCAGACGCCTCTGGATCTGGCAACAGCTGACGATATCAGAGCTTTGCTG ATAGATGCCATGCCCCCAGAGGCCTTACCTACCTGTTTTAAACCTCAGGCTACTGTAGTGAGTGCCTCTCTGATCTCACCAGCATCCACC CCCTCCTGCCTCTCGGCTGCCAGCAGCATAGACAACCTCACTGGCCCTTTAGCAGAGTTGGCCGTAGGAGGAGCCTCCAATGCAGGGGAT GGCGCCGCGGGAACAGAAAGGAAGGAAGGAGAAGTTGCTGGTCTTGACATGAATATCAGCCAATTTCTAAAAAGCCTTGGCCTTGAACAC CTTCGGGATATCTTTGAAACAGAACAGATTACACTAGATGTGTTGGCTGATATGGGTCATGAAGAGTTGAAAGAAATAGGCATCAATGCA TATGGGCACCGCCACAAATTAATCAAAGGAGTAGAAAGACTCTTAGGTGGACAACAAGGCACCAATCCTTATTTGACTTTTCACTGTGTT AATCAGGGAACGATTTTGCTGGATCTTGCTCCAGAAGATAAAGAATATCAGTCAGTGGAAGAAGAGATGCAAAGTACTATTCGAGAACAC AGAGATGGTGGTAATGCTGGCGGCATCTTCAACAGATACAATGTCATTCGAATTCAAAAAGTTGTCAACAAGAAGTTGAGGGAGCGGTTC TGCCACCGACAGAAGGAAGTGTCTGAGGAGAATCACAACCATCACAATGAGCGCATGTTGTTTCATGGTTCTCCTTTCATTAATGCCATT ATTCATAAAGGGTTTGATGAGCGACATGCATACATAGGAGGAATGTTTGGGGCCGGGATTTATTTTGCTGAAAACTCCTCAAAAAGCAAC CAATATGTTTATGGAATTGGAGGAGGAACAGGCTGCCCTACACACAAGGACAGGTCATGCTATATATGTCACAGACAAATGCTCTTCTGT AGAGTGACCCTTGGGAAATCCTTTCTGCAGTTTAGCACCATGAAAATGGCCCACGCGCCTCCAGGGCACCACTCAGTCATTGGTAGACCG AGCGTCAATGGGCTGGCATATGCTGAATATGTCATCTACAGAGGAGAACAGGCATACCCAGAGTATCTTATCACTTACCAGATCATGAAG CCAGAAGCCCCTTCCCAGACCGCAACAGCCGCAGAGCAGAAGACCTAGTGAATGCCTGCTGGTGAAGGCCAGATCAGATTTCAACCTGGG ACTGGATTACAGAGGATTGTTTCTAATAACAACATCAATATTCTAGAAGTCCCTGACAGCCTAGAAATAAGCTGTTTGTCTTCTATAAAG >30051_30051_2_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000220584_TNKS_chr8_9562173_ENST00000518281_length(amino acids)=991AA_BP=317 MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA CVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINF KQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQT CRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNR VSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTP LDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHN AASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDAMPPEALPTCFK PQATVVSASLISPASTPSCLSAASSIDNLTGPLAELAVGGASNAGDGAAGTERKEGEVAGLDMNISQFLKSLGLEHLRDIFETEQITLDV LADMGHEELKEIGINAYGHRHKLIKGVERLLGGQQGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYN VIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPT HKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTATAAEQK -------------------------------------------------------------- >30051_30051_3_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000220584_TNKS_chr8_9562173_ENST00000520408_length(transcript)=1152nt_BP=321nt AATCAGCGCCCGTCAGCCCACCCCACGAGGCCGCAGCTAGCCCCGCTGGCGGCCGAGGCCGGTTGAAGTGGGCGGAGCGGCGGGCGGGGC GTCGCCGTACTAGGCCTGCCCCCTGTCCGGCCAGCCCCTCGAAGCACCTACTCCACAGGTCCAGCCGGCCGGTGAGCGCCTGGGGACCGC AGAGGTGAGAGTCGCGCCCGGGAGTCCGCCGCCTGCGCCAGGATGGAGTTCGTGAAATGCCTTGGCCACCCCGAAGAGTTCTACAACCTG GTGCGCTTCCGGATCGGGGGCAAGCGGAAGGTGATGCCCAAGATGGACCAGTCGACTCCTTTACATCTAGCAGCGGGCTACAACAGAGTT CGAATAGTTCAGCTTCTTCTTCAGCATGGTGCTGATGTTCATGCAAAAGACAAAGGTGGACTTGTGCCTCTTCATAATGCATGTTCATAT GGACATTATGAAGTCACAGAACTGCTACTAAAGCATGGAGCTTGTGTTAATGCCATGGATCTCTGGCAGTTTACTCCACTGCACGAGGCT GCTTCCAAGAACCGTGTAGAAGTCTGCTCTTTGTTACTTAGCCATGGCGCTGATCCTACATTAGTCAACTGCCATGGCAAAAGTGCTGTG GATATGGCTCCAACTCCGGAGCTTAGGGAGAGATTGACTTATGAATTTAAAGGTCATTCTTTACTACAAGCAGCCAGAGAAGCAGACTTA GCTAAAGTTAAAAAAACACTCGCTCTGGAAATCATTAATTTCAAACAACCGCAGTCTCATGAAACAGCACTGCACTGTGCTGTGGCCTCT CTGCATCCCAAACGTAAACAAGTGACAGAATTGTTACTTAGAAAAGGAGCAAATGTTAATGAAAAAAATAAAGATTTCATGACTCCCCTG CATGTTGCAGCCGAAAGAGCCCATAATGATGTCATGGAAGTTCTGCATAAGCATGGCGCCAAGGTGAGGCACACACCTGAGCAGAGTGCC AGACTCAGCACTGAGCAGCCAGCTGCTCTTAACACTGCTTCTCTCTCTCCGATTTTTCTGAAGAAACTAATTTTATAAAGGACTATTAGT >30051_30051_3_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000220584_TNKS_chr8_9562173_ENST00000520408_length(amino acids)=281AA_BP=33 MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA CVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINF KQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKVRHTPEQSARLSTEQPAALNTAS -------------------------------------------------------------- >30051_30051_4_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000443614_TNKS_chr8_9562173_ENST00000310430_length(transcript)=8680nt_BP=193nt TCGAAGCACCTACTCCACAGGTCCAGCCGGCCGGTGAGCGCCTGGGGACCGCAGAGGTGAGAGTCGCGCCCGGGAGTCCGCCGCCTGCGC CAGGATGGAGTTCGTGAAATGCCTTGGCCACCCCGAAGAGTTCTACAACCTGGTGCGCTTCCGGATCGGGGGCAAGCGGAAGGTGATGCC CAAGATGGACCAGTCGACTCCTTTACATCTAGCAGCGGGCTACAACAGAGTTCGAATAGTTCAGCTTCTTCTTCAGCATGGTGCTGATGT TCATGCAAAAGACAAAGGTGGACTTGTGCCTCTTCATAATGCATGTTCATATGGACATTATGAAGTCACAGAACTGCTACTAAAGCATGG AGCTTGTGTTAATGCCATGGATCTCTGGCAGTTTACTCCACTGCACGAGGCTGCTTCCAAGAACCGTGTAGAAGTCTGCTCTTTGTTACT TAGCCATGGCGCTGATCCTACATTAGTCAACTGCCATGGCAAAAGTGCTGTGGATATGGCTCCAACTCCGGAGCTTAGGGAGAGATTGAC TTATGAATTTAAAGGTCATTCTTTACTACAAGCAGCCAGAGAAGCAGACTTAGCTAAAGTTAAAAAAACACTCGCTCTGGAAATCATTAA TTTCAAACAACCGCAGTCTCATGAAACAGCACTGCACTGTGCTGTGGCCTCTCTGCATCCCAAACGTAAACAAGTGACAGAATTGTTACT TAGAAAAGGAGCAAATGTTAATGAAAAAAATAAAGATTTCATGACTCCCCTGCATGTTGCAGCCGAAAGAGCCCATAATGATGTCATGGA AGTTCTGCATAAGCATGGCGCCAAGATGAATGCACTGGACACCCTTGGTCAGACTGCTTTGCATAGAGCCGCCCTAGCAGGTCACCTGCA GACCTGCCGCCTCCTGCTGAGTTACGGCTCTGACCCCTCCATCATCTCCTTACAAGGCTTCACAGCAGCACAGATGGGCAATGAAGCAGT GCAGCAGATTCTGAGTGAGAGTACACCTATACGTACTTCTGATGTTGATTATCGACTCTTAGAGGCATCTAAAGCTGGAGACTTGGAAAC TGTGAAGCAACTTTGCAGCTCTCAAAATGTGAATTGTAGAGACTTAGAGGGCCGGCATTCCACGCCCTTACACTTCGCAGCAGGCTACAA CCGCGTGTCTGTTGTAGAGTACCTGCTACACCACGGTGCCGATGTCCATGCCAAAGACAAGGGTGGCTTGGTGCCCCTTCATAATGCCTG TTCATATGGACACTATGAGGTGGCTGAGCTTTTAGTAAGGCATGGGGCTTCTGTCAATGTGGCGGACTTATGGAAATTTACCCCTCTCCA TGAAGCAGCAGCTAAAGGAAAGTATGAAATCTGCAAGCTCCTTTTAAAACATGGAGCAGATCCAACTAAAAAGAACAGAGATGGAAATAC ACCTTTGGATTTGGTAAAGGAAGGAGACACAGATATTCAGGACTTACTGAGAGGGGATGCTGCTTTGTTGGATGCTGCCAAGAAGGGCTG CCTGGCAAGAGTGCAGAAGCTCTGTACCCCAGAGAATATCAACTGCAGAGACACCCAGGGCAGAAATTCAACCCCTCTGCACCTGGCAGC AGGCTATAATAACCTGGAAGTAGCTGAATATCTTCTAGAGCATGGAGCTGATGTTAATGCCCAGGACAAGGGTGGTTTAATTCCTCTTCA TAATGCGGCATCTTATGGGCATGTTGACATAGCGGCTTTATTGATAAAATACAACACGTGTGTAAATGCAACAGATAAGTGGGCGTTTAC TCCCCTCCATGAAGCAGCCCAGAAAGGAAGGACGCAGCTGTGCGCCCTCCTCCTAGCGCATGGTGCAGACCCCACCATGAAGAACCAGGA AGGCCAGACGCCTCTGGATCTGGCAACAGCTGACGATATCAGAGCTTTGCTGATAGATGCCATGCCCCCAGAGGCCTTACCTACCTGTTT TAAACCTCAGGCTACTGTAGTGAGTGCCTCTCTGATCTCACCAGCATCCACCCCCTCCTGCCTCTCGGCTGCCAGCAGCATAGACAACCT CACTGGCCCTTTAGCAGAGTTGGCCGTAGGAGGAGCCTCCAATGCAGGGGATGGCGCCGCGGGAACAGAAAGGAAGGAAGGAGAAGTTGC TGGTCTTGACATGAATATCAGCCAATTTCTAAAAAGCCTTGGCCTTGAACACCTTCGGGATATCTTTGAAACAGAACAGATTACACTAGA TGTGTTGGCTGATATGGGTCATGAAGAGTTGAAAGAAATAGGCATCAATGCATATGGGCACCGCCACAAATTAATCAAAGGAGTAGAAAG ACTCTTAGGTGGACAACAAGGCACCAATCCTTATTTGACTTTTCACTGTGTTAATCAGGGAACGATTTTGCTGGATCTTGCTCCAGAAGA TAAAGAATATCAGTCAGTGGAAGAAGAGATGCAAAGTACTATTCGAGAACACAGAGATGGTGGTAATGCTGGCGGCATCTTCAACAGATA CAATGTCATTCGAATTCAAAAAGTTGTCAACAAGAAGTTGAGGGAGCGGTTCTGCCACCGACAGAAGGAAGTGTCTGAGGAGAATCACAA CCATCACAATGAGCGCATGTTGTTTCATGGTTCTCCTTTCATTAATGCCATTATTCATAAAGGGTTTGATGAGCGACATGCATACATAGG AGGAATGTTTGGGGCCGGGATTTATTTTGCTGAAAACTCCTCAAAAAGCAACCAATATGTTTATGGAATTGGAGGAGGAACAGGCTGCCC TACACACAAGGACAGGTCATGCTATATATGTCACAGACAAATGCTCTTCTGTAGAGTGACCCTTGGGAAATCCTTTCTGCAGTTTAGCAC CATGAAAATGGCCCACGCGCCTCCAGGGCACCACTCAGTCATTGGTAGACCGAGCGTCAATGGGCTGGCATATGCTGAATATGTCATCTA CAGAGGAGAACAGGCATACCCAGAGTATCTTATCACTTACCAGATCATGAAGCCAGAAGCCCCTTCCCAGACCGCAACAGCCGCAGAGCA GAAGACCTAGTGAATGCCTGCTGGTGAAGGCCAGATCAGATTTCAACCTGGGACTGGATTACAGAGGATTGTTTCTAATAACAACATCAA TATTCTAGAAGTCCCTGACAGCCTAGAAATAAGCTGTTTGTCTTCTATAAAGCATTGCTATAGTGATGAATAGTATGAGTAACTGATACA TACTCAACTGCTACTGTTCCCTTTGAGGAAATGTTTACAGGGGCGGCCTTTTAACATATCTCAGGCTCATTTTCATTGCAATTATCCATT TCTAAAACAAGATTGCTTCGATCTAGACTTGGAAATGGAAAATAAGAAAACCAATGCTTTTTCAAATGTTCACAATTCACACACTACATT TGTTTTGTTATGCATGACGTGTCTATAACAAATATACACATACGACAGGCAACAAGCTTGTTTTTGATTTGCCAGACATGCATCATTGGC TATTGTTTGTTTGTTTTTTGTTTTTTTGTGTTTTTTGGGTTACTTTGAAAATGAGCCAGAGCCTTCTTGAGGATATTTTGCACAAAGTCA CGCTGACAAAATCATTAGCAGTGCAACCCAAGCTTCTGGCTGAGCAAGATTCAGTTTCCACTTTTTAAAATTTTTTTATTTTGCTCTGTA GCTGCACTTCTCGTTATCATAAATTGAGATGAAAAGGAAAAAACATCAAGTTTTAGTACCTTTTTATGAATTGGCCTATCTTACAAGAGA AGGGCACAAACACCAACCTGACTTAGGAACGCCTAAATTCAGAGAAGTCAAAGCCGGTGAAGGCCACTTGCTCTTTCCAACACAAGCCTG CCACAGAGGTCTTCGGGACAGTACTGGAGATGCAGGTTGACACGGGCTTGAGTTCCAAGGTGAAAAAACTGGGGAGGCTGTGAAGGAAGA GCTGCATTAAGGAGGGTGAGGAGCGTGTGGTTCTGTATCATGGCAGCCCCAATGGATCCAGGGGATGCCTCCAAAAAATACATGCTTCCC TTCCCTTAATCTGTACTGTTGGGATTGTTACCCCTCCAAATTAGCTGCCTTATTTCAAAAGTCAGTGAAATTACTGCACTTGATGAGGGT CACAAAAATACCACTTGATTGTTTCTTTAGTTGAGAATGCTGGGATTCAGACTCGAATAGTGGATAGATACACACAAATGCAAGGACTTT TTTGTTTACTCCAGATTTGGGGTTTATTTTGAGTGGCATGCTTCAAATAGTTCATAAAGATCCTTGCATTAAATTTCTGAACCATTTCTT CAAACTTCTTAGTGTGTTTAGACAAGGAGAACAAAAATTGAAACCAAAGCCCTTTCTGTTATTTTTTCAATGAAGGTGAGAAAGAAATAC CATACAATTTTCTTTGTGAAATTACTGTTTATTTTCATCAACATTTACCAAGTGCCATTGACATTTATAAAAAAAAATGATCCTTTATAG TTCTTACACTTGCCCTTTTCACCTTAACTGAATATGAATTGAGTGCACTAACTTATTTACTTGATATACTGTGCATCTACTCTGCTTTGA AGCGAAAGAAATATAAACACGAGGAGGAATAGGAAAGACAGTGTGACACAAACTTGCCATTGCAATTCAAAGCCCTGAAAACGATGGGTT TAATGCAAGGTGATTAAGCTGTGACCTCCTTTAATCTCCTGAAGCAAAATAAAATGGTTACATGCAAAACTTCTAGAAATAGACTCTTAA AATATATACATTTTGCTTTGATTTTGGCTTCAACCCAGTGCTGGAACTAGGCATCCAGACTAGTTTGAATGTTTGTAGCTGAATTTTTAT GGGTCCTCAAAATTAAATCGAGAATTAGCCTCAGTTGTTGCTTCTTTTGAAGTTTCAGTGACCCAAGCTGGGTGTTTGTGTCTTGGCTAC TTGTTTAATAGCACTAGAATTCCAGGTGAAGCTTTGAGAGTTGATATTCATTAAGAGGGCTTTTTTTCCCCTTCTTTCCTTCTCTTTTGC TGTAACAAAGGGTTGAAGAAATTGCCATCTGTGTAGTTTTCAGTAGCTGTCAAGTGTGTCTTACTTACCTTCCCCCAGACGTAGTTTAAA ATGGTAAACACAGCTGTGATTTTTAGTTAAGTAAAAGAGTTAATATGATATAGATATGGAAAGCTTTATGGCTTCATTAAAAAGATAAAC CACTACCTAACTGTGGTTGTATGTTGTTTCCATCATACTAACTAGATGAATGGATGCGCCAGTTTTCATCTTGGTCCTTACACTTGAGAA GTTAAACTGTGGTTCAGTATTTAAACTGCCAGTGTTATACGTCTCATGCTCTGTGTGCCAGGTGAAGGTACTGTGTAAGGAAGACATTTG CGGTGCTTCTTGTCCTATAATGATTCAAGTATATAGTAGTTCTTGAAAGAGTGTGCATATATTACTCATCTGCTTAAGAGAGTGGGTTAA TGGATATATCAGAGGAGCCAAATACATTTTTTTCAGAACTTGAAAACCAAAGGTCATCATGAGTGCACTCAAAAGTTAGGACAAGTTTAT TACATTTGGGATTTTCATCTGTAGCCGTATGAAGAACCCTTTCCAATATAAAAGCATGGCATTAAATTAGGCTGAAGTCTTTTATTTTTT GTATATGTACTATATAGAAATACTAGCAAGTTAGGATCATCCAATATGGCCTACCCCGAAATGGCCCCTCTGTTTCCCTAACCACATGGA AGAAAGAATCTGAACGTCTCCACCGGCTCTACCCGAGTTCCAAAACTAAAGGGCTTCTCCAGACCTGATGGTTCCAGTTTACCTGCTGTT GGCCTGCTGGATACTTGACTCAGGCATAAATTAAGTGCCCTGGTCCCGAACTTTCTCCCTGTATTTGACCTCCTTCCCTCTTTCCTAAAT TACTAGTCTGGAATTAAAATTAGCTCCAGCAATGACCTTTGACTCCATTCATTTTCTCCTCATCTTGGGTCTTAAAAAAGGAGACCAGAT ACCTCCTAGCTTTTGTATCACAACCAGGAATGGGTATTAGGCCTCATGCGCTTTGCTCAGAACACTGCCGCTTTGTTAACAAATGACAGC ATGGAACCCAGAGTTTTGATTCGATGCAAAATAACAGCAGTGCAACCAGGATTCTTGTTTTCCTTTTCCTTCTTGGAGTTTGGAATTTCT AGCTTTTCAAGCAGCATAAGTAGAATCAACATTAGGATGTTTTCATGAAATAGCATCCTTATACTTCTTTGAGCTTGATGTTAGTGGCTA GACTGATTTCCCTTTGCTCTCAAAATACAAAGTGCATTGAAGTATACAGAGAAATGCCTGAATATGGCAAGCAAATAATGTAGATTAACA TTCTATTATTGTATCCGTTTTACAAAAAATAAAATTTTGATATATGCCGGAGAACGGCATTAGAATGCAATAAGTTGTCTAGGTTTTTCT GTTTCAGTGTCTCTCCCAATGGCACGAAGGGTTATTGGGCATTGTCCCCACCCCCGCCTTTTTAACATGTGCACTATCTGGATTCCTGTA AATGGCCTTGCAAACAGAAGTGGTGTGTATTTTCAAGCACCTTTCCCCCATTGTATCCGAATCCCTCTTGTGTGATATCTGTGACAAATA GCCTTCTTCTTGTGTTTTCTGTTGGACTAATTGTCTCACGTAAAGCTATAGACCTTACTAATTTGGCAGGTATTCAAAACTGCCATTAAG ATAGGATTTCATGTCAGATACGTATTTAAAGAGTAAAGTCAAATTTGTTTAATGTCAGATCAGTGACAGAAGTGAAAAGAAAGTAATTGT GAAAGTGATGTTTGAGCTATTGTACACATCTAGCATATGGAAAGCAAATGCACTCGAAAACTACTATTCTAGAACATGAGGCTTCTTCAG CAACTTGTGCACTCTGCCATTAATAAATTAAATTTTTCCCCTCTAGAAAGCCTTAACTATGGCGGAAACTTTTTAACCTTTTATATTTTA ATAAATAAAACATTGTAGTCCCATTTCTTAGTGTTTGAAAGGTGTGTCAGTGAGTCGGCCATGTCTCCATGTGTTTCAGACCTGTTCATC TTATTTTATGATGGTATATTTCATAAGTAATATTCCCTTACATGCAATGGAGCTGATTAAAATTAATCCATTTCAATTTCTCCATATTGG AACTTCCTCAGCTACCAGATTTCTGGTTTGGAGAAGTGCTGGAAAGATTTCAAAGCCTATTCAGTTGTGTATGTGGGGATACGACAGCAA CTGTGATACCTTGTAGAATATGAGTGATATGCAAGCTGTGTTTTTTAATTGTTTTAAAATGTAAATTATGGTTATGCTAAAGTGAAAACC TAGAGGAAGCTAATGATTTTATATACTTTGCACGACCAAATATGGTCGTAGTATGACGAGTTTTATACATTGCCAGAGAGTTCTGCCTCC TCTGAAATAACATTCGCACTGTAGATTGCATTTCGGCTTTTCCTCCTTTCACATTCTTTTTTGCTTTACACTTCACGTCTTCGCACCTGC CCTACCTCCCATCCTTTCAAAGAGGTTTCTTTCACGTTCCAGAATTCAGATTGTTCTGTGATTTCTTTTACATCAGTCTACCCATTTCTG CAGGCAGCCCTGAAAGCCCTTGTGTTGATTCAGAGTGTTTGCAGAGAAATGCAGTTGAACCCTGGTAGTGGGGTGTCCCTCACACACCCG CGCACCCCTCCCAAAGTTCAGGATGAAAGGCTAGAAAACCCATTCAAAGTTAGGAAAGAACACAGATCTTTGAGGCCGATAGCCTAGACC TAGAAGATGACCTTGAGTATGTAAACATTGTCTCCGTGACACAAAACACTGAAACTCTTCATGTGCATATAACACCTGCTTCTGCTCCCA TTGTTTCAAGCTCATCTTATCTTTGTAGTAGTAATGTTTGTCTTTGATACCTACAAACTAAAAAGGTACTTTTATCAAGGTTTCTCAAAA CATTTACAAAACCAGCTTTGAGAAAATGTTATGTTGCCTGGCAACAGCACTCGGAGTAGTAATTGTGTTTTCTCATTGTGATGTTGGTCT GTGTGAGCAACCAGTGTAGTGACTCTTTGGTTCATTATTCGTGTTGTTTTTATTTTTAGTCTCTGTGTGACCCAACAGTGGCAGGGGTTA CAACCCCCTCTCCTTTCTTTTTTGTATTTATCTATTTGTAGGATTGTCAGATCAAGTACAAGATGCCCAGTTAAGTTTGAATTTCAGAGA AACAATTTCACGTTAAGAATGTTTCATGCAATATTTGGCATATATTTACAGTAAAAGCATTCATTATTTGTCTGAAATTCAAATTTAACT GAGCATGCTGGTTTTTCTCATTGTTTGGTTTTTCTAAATCTGGCAATCCTACAGCTGTGGTCATGGGAAATCACCTACAGCATGTTAAAG TCCTCTAGTCATCATCTCGTCACCTGAAATGGAAGTCCTTTTTCCCTCACCCTCCACTTCTTTCCAAAGGAGGGCATCAAGGAACTTAAC CTGCCTGCCTGGTGGGTTTCTATTTAAGACATCTTTGTGATTATATTTAACCTGCAATTGTGCTTTGGCTTAATGTCTAGCTCACTGTAC >30051_30051_4_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000443614_TNKS_chr8_9562173_ENST00000310430_length(amino acids)=991AA_BP=317 MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA CVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINF KQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQT CRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNR VSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTP LDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHN AASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDAMPPEALPTCFK PQATVVSASLISPASTPSCLSAASSIDNLTGPLAELAVGGASNAGDGAAGTERKEGEVAGLDMNISQFLKSLGLEHLRDIFETEQITLDV LADMGHEELKEIGINAYGHRHKLIKGVERLLGGQQGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYN VIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPT HKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTATAAEQK -------------------------------------------------------------- >30051_30051_5_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000443614_TNKS_chr8_9562173_ENST00000518281_length(transcript)=3263nt_BP=193nt TCGAAGCACCTACTCCACAGGTCCAGCCGGCCGGTGAGCGCCTGGGGACCGCAGAGGTGAGAGTCGCGCCCGGGAGTCCGCCGCCTGCGC CAGGATGGAGTTCGTGAAATGCCTTGGCCACCCCGAAGAGTTCTACAACCTGGTGCGCTTCCGGATCGGGGGCAAGCGGAAGGTGATGCC CAAGATGGACCAGTCGACTCCTTTACATCTAGCAGCGGGCTACAACAGAGTTCGAATAGTTCAGCTTCTTCTTCAGCATGGTGCTGATGT TCATGCAAAAGACAAAGGTGGACTTGTGCCTCTTCATAATGCATGTTCATATGGACATTATGAAGTCACAGAACTGCTACTAAAGCATGG AGCTTGTGTTAATGCCATGGATCTCTGGCAGTTTACTCCACTGCACGAGGCTGCTTCCAAGAACCGTGTAGAAGTCTGCTCTTTGTTACT TAGCCATGGCGCTGATCCTACATTAGTCAACTGCCATGGCAAAAGTGCTGTGGATATGGCTCCAACTCCGGAGCTTAGGGAGAGATTGAC TTATGAATTTAAAGGTCATTCTTTACTACAAGCAGCCAGAGAAGCAGACTTAGCTAAAGTTAAAAAAACACTCGCTCTGGAAATCATTAA TTTCAAACAACCGCAGTCTCATGAAACAGCACTGCACTGTGCTGTGGCCTCTCTGCATCCCAAACGTAAACAAGTGACAGAATTGTTACT TAGAAAAGGAGCAAATGTTAATGAAAAAAATAAAGATTTCATGACTCCCCTGCATGTTGCAGCCGAAAGAGCCCATAATGATGTCATGGA AGTTCTGCATAAGCATGGCGCCAAGATGAATGCACTGGACACCCTTGGTCAGACTGCTTTGCATAGAGCCGCCCTAGCAGGTCACCTGCA GACCTGCCGCCTCCTGCTGAGTTACGGCTCTGACCCCTCCATCATCTCCTTACAAGGCTTCACAGCAGCACAGATGGGCAATGAAGCAGT GCAGCAGATTCTGAGTGAGAGTACACCTATACGTACTTCTGATGTTGATTATCGACTCTTAGAGGCATCTAAAGCTGGAGACTTGGAAAC TGTGAAGCAACTTTGCAGCTCTCAAAATGTGAATTGTAGAGACTTAGAGGGCCGGCATTCCACGCCCTTACACTTCGCAGCAGGCTACAA CCGCGTGTCTGTTGTAGAGTACCTGCTACACCACGGTGCCGATGTCCATGCCAAAGACAAGGGTGGCTTGGTGCCCCTTCATAATGCCTG TTCATATGGACACTATGAGGTGGCTGAGCTTTTAGTAAGGCATGGGGCTTCTGTCAATGTGGCGGACTTATGGAAATTTACCCCTCTCCA TGAAGCAGCAGCTAAAGGAAAGTATGAAATCTGCAAGCTCCTTTTAAAACATGGAGCAGATCCAACTAAAAAGAACAGAGATGGAAATAC ACCTTTGGATTTGGTAAAGGAAGGAGACACAGATATTCAGGACTTACTGAGAGGGGATGCTGCTTTGTTGGATGCTGCCAAGAAGGGCTG CCTGGCAAGAGTGCAGAAGCTCTGTACCCCAGAGAATATCAACTGCAGAGACACCCAGGGCAGAAATTCAACCCCTCTGCACCTGGCAGC AGGCTATAATAACCTGGAAGTAGCTGAATATCTTCTAGAGCATGGAGCTGATGTTAATGCCCAGGACAAGGGTGGTTTAATTCCTCTTCA TAATGCGGCATCTTATGGGCATGTTGACATAGCGGCTTTATTGATAAAATACAACACGTGTGTAAATGCAACAGATAAGTGGGCGTTTAC TCCCCTCCATGAAGCAGCCCAGAAAGGAAGGACGCAGCTGTGCGCCCTCCTCCTAGCGCATGGTGCAGACCCCACCATGAAGAACCAGGA AGGCCAGACGCCTCTGGATCTGGCAACAGCTGACGATATCAGAGCTTTGCTGATAGATGCCATGCCCCCAGAGGCCTTACCTACCTGTTT TAAACCTCAGGCTACTGTAGTGAGTGCCTCTCTGATCTCACCAGCATCCACCCCCTCCTGCCTCTCGGCTGCCAGCAGCATAGACAACCT CACTGGCCCTTTAGCAGAGTTGGCCGTAGGAGGAGCCTCCAATGCAGGGGATGGCGCCGCGGGAACAGAAAGGAAGGAAGGAGAAGTTGC TGGTCTTGACATGAATATCAGCCAATTTCTAAAAAGCCTTGGCCTTGAACACCTTCGGGATATCTTTGAAACAGAACAGATTACACTAGA TGTGTTGGCTGATATGGGTCATGAAGAGTTGAAAGAAATAGGCATCAATGCATATGGGCACCGCCACAAATTAATCAAAGGAGTAGAAAG ACTCTTAGGTGGACAACAAGGCACCAATCCTTATTTGACTTTTCACTGTGTTAATCAGGGAACGATTTTGCTGGATCTTGCTCCAGAAGA TAAAGAATATCAGTCAGTGGAAGAAGAGATGCAAAGTACTATTCGAGAACACAGAGATGGTGGTAATGCTGGCGGCATCTTCAACAGATA CAATGTCATTCGAATTCAAAAAGTTGTCAACAAGAAGTTGAGGGAGCGGTTCTGCCACCGACAGAAGGAAGTGTCTGAGGAGAATCACAA CCATCACAATGAGCGCATGTTGTTTCATGGTTCTCCTTTCATTAATGCCATTATTCATAAAGGGTTTGATGAGCGACATGCATACATAGG AGGAATGTTTGGGGCCGGGATTTATTTTGCTGAAAACTCCTCAAAAAGCAACCAATATGTTTATGGAATTGGAGGAGGAACAGGCTGCCC TACACACAAGGACAGGTCATGCTATATATGTCACAGACAAATGCTCTTCTGTAGAGTGACCCTTGGGAAATCCTTTCTGCAGTTTAGCAC CATGAAAATGGCCCACGCGCCTCCAGGGCACCACTCAGTCATTGGTAGACCGAGCGTCAATGGGCTGGCATATGCTGAATATGTCATCTA CAGAGGAGAACAGGCATACCCAGAGTATCTTATCACTTACCAGATCATGAAGCCAGAAGCCCCTTCCCAGACCGCAACAGCCGCAGAGCA GAAGACCTAGTGAATGCCTGCTGGTGAAGGCCAGATCAGATTTCAACCTGGGACTGGATTACAGAGGATTGTTTCTAATAACAACATCAA TATTCTAGAAGTCCCTGACAGCCTAGAAATAAGCTGTTTGTCTTCTATAAAGCATTGCTATAGTGATGAATAGTATGAGTAACTGATACA >30051_30051_5_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000443614_TNKS_chr8_9562173_ENST00000518281_length(amino acids)=991AA_BP=317 MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA CVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINF KQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQT CRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNR VSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTP LDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHN AASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDAMPPEALPTCFK PQATVVSASLISPASTPSCLSAASSIDNLTGPLAELAVGGASNAGDGAAGTERKEGEVAGLDMNISQFLKSLGLEHLRDIFETEQITLDV LADMGHEELKEIGINAYGHRHKLIKGVERLLGGQQGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYN VIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPT HKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTATAAEQK -------------------------------------------------------------- >30051_30051_6_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000443614_TNKS_chr8_9562173_ENST00000520408_length(transcript)=1024nt_BP=193nt TCGAAGCACCTACTCCACAGGTCCAGCCGGCCGGTGAGCGCCTGGGGACCGCAGAGGTGAGAGTCGCGCCCGGGAGTCCGCCGCCTGCGC CAGGATGGAGTTCGTGAAATGCCTTGGCCACCCCGAAGAGTTCTACAACCTGGTGCGCTTCCGGATCGGGGGCAAGCGGAAGGTGATGCC CAAGATGGACCAGTCGACTCCTTTACATCTAGCAGCGGGCTACAACAGAGTTCGAATAGTTCAGCTTCTTCTTCAGCATGGTGCTGATGT TCATGCAAAAGACAAAGGTGGACTTGTGCCTCTTCATAATGCATGTTCATATGGACATTATGAAGTCACAGAACTGCTACTAAAGCATGG AGCTTGTGTTAATGCCATGGATCTCTGGCAGTTTACTCCACTGCACGAGGCTGCTTCCAAGAACCGTGTAGAAGTCTGCTCTTTGTTACT TAGCCATGGCGCTGATCCTACATTAGTCAACTGCCATGGCAAAAGTGCTGTGGATATGGCTCCAACTCCGGAGCTTAGGGAGAGATTGAC TTATGAATTTAAAGGTCATTCTTTACTACAAGCAGCCAGAGAAGCAGACTTAGCTAAAGTTAAAAAAACACTCGCTCTGGAAATCATTAA TTTCAAACAACCGCAGTCTCATGAAACAGCACTGCACTGTGCTGTGGCCTCTCTGCATCCCAAACGTAAACAAGTGACAGAATTGTTACT TAGAAAAGGAGCAAATGTTAATGAAAAAAATAAAGATTTCATGACTCCCCTGCATGTTGCAGCCGAAAGAGCCCATAATGATGTCATGGA AGTTCTGCATAAGCATGGCGCCAAGGTGAGGCACACACCTGAGCAGAGTGCCAGACTCAGCACTGAGCAGCCAGCTGCTCTTAACACTGC TTCTCTCTCTCCGATTTTTCTGAAGAAACTAATTTTATAAAGGACTATTAGTTCGTACTTAAATTCATGGATTCTCCTATAAAGCTGATT >30051_30051_6_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000443614_TNKS_chr8_9562173_ENST00000520408_length(amino acids)=281AA_BP=33 MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA CVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINF KQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKVRHTPEQSARLSTEQPAALNTAS -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for FDFT1-TNKS |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for FDFT1-TNKS |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for FDFT1-TNKS |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | FDFT1 | C0006868 | Cannabis Abuse | 1 | CTD_human |
| Hgene | FDFT1 | C0006870 | Cannabis Dependence | 1 | CTD_human |
| Hgene | FDFT1 | C0009171 | Cocaine Abuse | 1 | CTD_human |
| Hgene | FDFT1 | C0018614 | Hashish Abuse | 1 | CTD_human |
| Hgene | FDFT1 | C0024809 | Marijuana Abuse | 1 | CTD_human |
| Hgene | FDFT1 | C0031391 | Phencyclidine Abuse | 1 | CTD_human |
| Hgene | FDFT1 | C0036572 | Seizures | 1 | GENOMICS_ENGLAND |
| Hgene | FDFT1 | C0037268 | Skin Abnormalities | 1 | GENOMICS_ENGLAND |
| Hgene | FDFT1 | C0234398 | Visual Cortex Disorder | 1 | GENOMICS_ENGLAND |
| Hgene | FDFT1 | C0236735 | Cannabis-Related Disorder | 1 | CTD_human |
| Hgene | FDFT1 | C0236736 | Cocaine-Related Disorders | 1 | CTD_human |
| Hgene | FDFT1 | C0236742 | Phencyclidine-Related Disorders | 1 | CTD_human |
| Hgene | FDFT1 | C0600427 | Cocaine Dependence | 1 | CTD_human |
| Hgene | FDFT1 | C2239176 | Liver carcinoma | 1 | CTD_human |
| Hgene | FDFT1 | C3553450 | Profound global developmental delay | 1 | GENOMICS_ENGLAND |
| Hgene | FDFT1 | C3714756 | Intellectual Disability | 1 | GENOMICS_ENGLAND |
| Hgene | FDFT1 | C4022810 | Abnormality of nervous system morphology | 1 | GENOMICS_ENGLAND |
| Hgene | FDFT1 | C4025871 | Abnormality of the face | 1 | GENOMICS_ENGLAND |
| Hgene | FDFT1 | C4048268 | Cortical visual impairment | 1 | GENOMICS_ENGLAND |
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