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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ANKRD28-PHF21A (FusionGDB2 ID:HG23243TG51317)

Fusion Gene Summary for ANKRD28-PHF21A

check button Fusion gene summary
Fusion gene informationFusion gene name: ANKRD28-PHF21A
Fusion gene ID: hg23243tg51317
HgeneTgene
Gene symbol

ANKRD28

PHF21A

Gene ID

23243

51317

Gene nameankyrin repeat domain 28PHD finger protein 21A
SynonymsCFAP79|FAP79|PITK|PPP1R65BHC80|BM-006|IDDBCS|NEDMS
Cytomap('ANKRD28')('PHF21A')

3p25.1

11p11.2

Type of geneprotein-codingprotein-coding
Descriptionserine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit APP6-ARS-Aankyrin repeat domain-containing protein 28phosphatase interactor targeting K proteinphosphatase interactor targeting protein hnRNP Kprotein phosphatase 1, regulatory PHD finger protein 21ABHC80aBRAF35-HDAC complex protein BHC80BRAF35/HDAC2 complex (80 kDa)
Modification date2020032020200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000383777, ENST00000399451, 
ENST00000497037, 
Fusion gene scores* DoF score18 X 13 X 13=304213 X 10 X 8=1040
# samples 2114
** MAII scorelog2(21/3042*10)=-3.85655892005837
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/1040*10)=-2.89308479608349
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANKRD28 [Title/Abstract] AND PHF21A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANKRD28(15836729)-PHF21A(45975176), # samples:1
Anticipated loss of major functional domain due to fusion event.ANKRD28-PHF21A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ANKRD28-PHF21A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ANKRD28-PHF21A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ANKRD28-PHF21A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ANKRD28 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across PHF21A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-EW-A1OYANKRD28chr3

15836729

-PHF21Achr11

45975176

-


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Fusion Gene ORF analysis for ANKRD28-PHF21A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000383777ENST00000527753ANKRD28chr3

15836729

-PHF21Achr11

45975176

-
5CDS-5UTRENST00000399451ENST00000527753ANKRD28chr3

15836729

-PHF21Achr11

45975176

-
5UTR-3CDSENST00000497037ENST00000257821ANKRD28chr3

15836729

-PHF21Achr11

45975176

-
5UTR-3CDSENST00000497037ENST00000323180ANKRD28chr3

15836729

-PHF21Achr11

45975176

-
5UTR-3CDSENST00000497037ENST00000418153ANKRD28chr3

15836729

-PHF21Achr11

45975176

-
5UTR-5UTRENST00000497037ENST00000527753ANKRD28chr3

15836729

-PHF21Achr11

45975176

-
In-frameENST00000383777ENST00000257821ANKRD28chr3

15836729

-PHF21Achr11

45975176

-
In-frameENST00000383777ENST00000323180ANKRD28chr3

15836729

-PHF21Achr11

45975176

-
In-frameENST00000383777ENST00000418153ANKRD28chr3

15836729

-PHF21Achr11

45975176

-
In-frameENST00000399451ENST00000257821ANKRD28chr3

15836729

-PHF21Achr11

45975176

-
In-frameENST00000399451ENST00000323180ANKRD28chr3

15836729

-PHF21Achr11

45975176

-
In-frameENST00000399451ENST00000418153ANKRD28chr3

15836729

-PHF21Achr11

45975176

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000383777ANKRD28chr315836729-ENST00000257821PHF21Achr1145975176-590821001259419
ENST00000383777ANKRD28chr315836729-ENST00000323180PHF21Achr1145975176-252121001118372
ENST00000383777ANKRD28chr315836729-ENST00000418153PHF21Achr1145975176-174721001259419
ENST00000399451ANKRD28chr315836729-ENST00000257821PHF21Achr1145975176-61774793681528386
ENST00000399451ANKRD28chr315836729-ENST00000323180PHF21Achr1145975176-27904793681387339
ENST00000399451ANKRD28chr315836729-ENST00000418153PHF21Achr1145975176-20164793681528386

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000383777ENST00000257821ANKRD28chr315836729-PHF21Achr1145975176-0.0016202680.9983797
ENST00000383777ENST00000323180ANKRD28chr315836729-PHF21Achr1145975176-0.0010602160.9989398
ENST00000383777ENST00000418153ANKRD28chr315836729-PHF21Achr1145975176-0.002945840.9970541
ENST00000399451ENST00000257821ANKRD28chr315836729-PHF21Achr1145975176-0.0015561730.9984439
ENST00000399451ENST00000323180ANKRD28chr315836729-PHF21Achr1145975176-0.0011974740.99880254
ENST00000399451ENST00000418153ANKRD28chr315836729-PHF21Achr1145975176-0.0048503720.9951497

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Fusion Genomic Features for ANKRD28-PHF21A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ANKRD28-PHF21A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:15836729/chr11:45975176)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-22840_69701087.0RepeatNote=ANK 1
TgenePHF21Achr3:15836729chr11:45975176ENST00000257821818558_603332682.0Coiled coilOntology_term=ECO:0000255
TgenePHF21Achr3:15836729chr11:45975176ENST00000323180818558_603332635.0Coiled coilOntology_term=ECO:0000255
TgenePHF21Achr3:15836729chr11:45975176ENST00000418153818558_603331681.0Coiled coilOntology_term=ECO:0000255
TgenePHF21Achr3:15836729chr11:45975176ENST00000257821818425_437332682.0DNA bindingNote=A.T hook
TgenePHF21Achr3:15836729chr11:45975176ENST00000323180818425_437332635.0DNA bindingNote=A.T hook
TgenePHF21Achr3:15836729chr11:45975176ENST00000418153818425_437331681.0DNA bindingNote=A.T hook
TgenePHF21Achr3:15836729chr11:45975176ENST00000257821818486_680332682.0RegionNote=Required for transcriptional repression
TgenePHF21Achr3:15836729chr11:45975176ENST00000323180818486_680332635.0RegionNote=Required for transcriptional repression
TgenePHF21Achr3:15836729chr11:45975176ENST00000418153818486_680331681.0RegionNote=Required for transcriptional repression
TgenePHF21Achr3:15836729chr11:45975176ENST00000257821818488_535332682.0Zinc fingerPHD-type
TgenePHF21Achr3:15836729chr11:45975176ENST00000323180818488_535332635.0Zinc fingerPHD-type
TgenePHF21Achr3:15836729chr11:45975176ENST00000418153818488_535331681.0Zinc fingerPHD-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228106_135701087.0RepeatNote=ANK 3
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228139_168701087.0RepeatNote=ANK 4
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228172_201701087.0RepeatNote=ANK 5
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228205_234701087.0RepeatNote=ANK 6
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228238_267701087.0RepeatNote=ANK 7
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228271_301701087.0RepeatNote=ANK 8
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228305_334701087.0RepeatNote=ANK 9
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228338_367701087.0RepeatNote=ANK 10
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228371_400701087.0RepeatNote=ANK 11
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228404_433701087.0RepeatNote=ANK 12
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228437_466701087.0RepeatNote=ANK 13
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228470_500701087.0RepeatNote=ANK 14
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228504_534701087.0RepeatNote=ANK 15
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228549_578701087.0RepeatNote=ANK 16
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228582_611701087.0RepeatNote=ANK 17
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228616_645701087.0RepeatNote=ANK 18
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228652_681701087.0RepeatNote=ANK 19
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228685_714701087.0RepeatNote=ANK 20
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228718_747701087.0RepeatNote=ANK 21
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-22873_102701087.0RepeatNote=ANK 2
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228755_784701087.0RepeatNote=ANK 22
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228787_817701087.0RepeatNote=ANK 23
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228822_851701087.0RepeatNote=ANK 24
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228855_885701087.0RepeatNote=ANK 25
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228889_918701087.0RepeatNote=ANK 26
HgeneANKRD28chr3:15836729chr11:45975176ENST00000383777-228925_954701087.0RepeatNote=ANK 27
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228106_135371054.0RepeatNote=ANK 3
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228139_168371054.0RepeatNote=ANK 4
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228172_201371054.0RepeatNote=ANK 5
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228205_234371054.0RepeatNote=ANK 6
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228238_267371054.0RepeatNote=ANK 7
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228271_301371054.0RepeatNote=ANK 8
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228305_334371054.0RepeatNote=ANK 9
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228338_367371054.0RepeatNote=ANK 10
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228371_400371054.0RepeatNote=ANK 11
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228404_433371054.0RepeatNote=ANK 12
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-22840_69371054.0RepeatNote=ANK 1
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228437_466371054.0RepeatNote=ANK 13
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228470_500371054.0RepeatNote=ANK 14
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228504_534371054.0RepeatNote=ANK 15
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228549_578371054.0RepeatNote=ANK 16
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228582_611371054.0RepeatNote=ANK 17
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228616_645371054.0RepeatNote=ANK 18
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228652_681371054.0RepeatNote=ANK 19
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228685_714371054.0RepeatNote=ANK 20
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228718_747371054.0RepeatNote=ANK 21
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-22873_102371054.0RepeatNote=ANK 2
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228755_784371054.0RepeatNote=ANK 22
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228787_817371054.0RepeatNote=ANK 23
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228822_851371054.0RepeatNote=ANK 24
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228855_885371054.0RepeatNote=ANK 25
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228889_918371054.0RepeatNote=ANK 26
HgeneANKRD28chr3:15836729chr11:45975176ENST00000399451-228925_954371054.0RepeatNote=ANK 27
TgenePHF21Achr3:15836729chr11:45975176ENST000002578218184_108332682.0Compositional biasNote=Gln-rich
TgenePHF21Achr3:15836729chr11:45975176ENST000003231808184_108332635.0Compositional biasNote=Gln-rich
TgenePHF21Achr3:15836729chr11:45975176ENST000004181538184_108331681.0Compositional biasNote=Gln-rich


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Fusion Gene Sequence for ANKRD28-PHF21A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>4671_4671_1_ANKRD28-PHF21A_ANKRD28_chr3_15836729_ENST00000383777_PHF21A_chr11_45975176_ENST00000257821_length(transcript)=5908nt_BP=210nt
ATGAGTCGAGTGTGTATTGTTGTTTTGGAGGAGGTAGAAGATGAATCTCCTGCATTCATTTCTAAATTGCCACAGGAAAATAAATCCCTA
CATTCTCCACCTTCTGGAAATGTATTGGTAAGATATCCATCACTGGTGCAAGCTATATTTAACGGAGATCCTGATGAAGTTCGAGCACTA
ATATTTAAGAAAGAAGATGTTAACTTTCAGACAGTTAAATCTCACACAGAAACAGATGAGAAACAAACAGAGAGCCGCACCATCACCCCA
CCTGCTGCACCCAAACCAAAACGGGAGGAGAACCCTCAGAAACTTGCCTTCATGGTGTCTCTAGGGTTGGTAACACATGACCATCTAGAA
GAAATCCAAAGCAAGAGGCAAGAGCGAAAAAGAAGAACAACAGCAAATCCGGTCTACAGTGGAGCAGTCTTTGAGCCAGAGCGTAAGAAG
AGTGCAGTGACATACCTAAACAGCACAATGCACCCTGGGACCCGGAAGAGAGGTCGTCCTCCAAAATACAATGCAGTGCTGGGGTTTGGA
GCCCTTACCCCAACATCCCCCCAATCCAGTCATCCTGACTCCCCTGAAAATGAAAAGACAGAGACCACATTCACTTTCCCTGCACCTGTT
CAGCCTGTGTCCCTGCCCAGCCCCACCTCCACAGACGGTGATATTCATGAGGATTTTTGCAGCGTTTGCAGAAAAAGTGGCCAGTTACTG
ATGTGCGACACATGTTCCCGTGTATATCATTTGGACTGCTTAGACCCCCCTCTGAAAACAATTCCCAAGGGCATGTGGATCTGTCCCAGA
TGTCAGGACCAGATGCTGAAGAAGGAAGAAGCAATTCCATGGCCTGGAACTTTAGCAATTGTTCATTCCTATATTGCCTACAAAGCAGCA
AAAGAAGAAGAGAAACAGAAGTTACTTAAATGGAGTTCAGATTTAAAACAAGAACGAGAACAACTAGAGCAAAAGGTGAAACAGCTCAGC
AATTCCATAAGTAAATGCATGGAAATGAAGAACACCATCCTGGCCCGGCAGAAGGAGATGCACAGCTCCCTGGAGAAGGTAAAACAGCTG
ATTCGCCTCATCCACGGCATCGACCTCTCCAAACCTGTAGACTCTGAGGCCACTGTGGGGGCCATCTCCAATGGCCCGGACTGCACCCCC
CCTGCCAATGCCGCCACCTCCACGCCGGCCCCTTCCCCCTCCTCCCAGAGCTGCACAGCGAACTGTAACCAGGGGGAAGAGACTAAATAA
CAGAGCCCCTCTAGGAGAAGCCACGGGATCCCGGCGGCAAGGAGAACAGAACACTGAAGACTCTAGAAAAGCAAAGCCGGATTTCTGGAA
AGTGCAGAATTCTTTTGGTTCTTTGGTTCCAGAGAGAGAGAAGATGCTTGTGCCAGGTGGCACCAGAGTTTGCCAATTGATCCTTCTTAT
TCTGTGTGTACATGCAAAGATTGGACCATGTTACATGAAATAGTGCCAGCTGGAGGTTCTTTGCCAGCACCATGCCAAGTGAAATAATAT
ATTTACTCTCTCTATTATACACCAGTGTGTGCCTGCAGCAGCCTCCACAGCCACGATGGGTTTGTTTCTGTTTTCTTGGGTGGGGAGCAG
GGACGGGCGGAGGGAGGAGAGCAGGTTTCAGATCCTTACTTGCCGAGCCGTTTGTTTAGGTAGAGAAGACAAGTCCAAAGAGTGTGTGGG
CTTTCCTGTTTCTAAACTTTCGCTACTATAAAACCAAAAAAAGGAATTGAGATTTCACCAACCCCAGTGCCCAGAAGAGGGAAGGGGAGT
GGCTGGAGGGAGCAGGGGGTGGGACAGTGTATCAAATAAGCAGTATTTAATCACCTCTGGCGGGGGCCTCGTGCAAGGGGAGACTGACAC
CAAGAACAGCCAGTAGGTTCTTCTCCCCTGCACTCTGCTCCCTGCGCGGTAACCCCACCACTCCTGAAGCCTGCCCAGTCTCCTTCCTTC
CCTGCTTGGTGAGTCGCGCATCTCCGTGGTTATCCCGCTGTCTCCTCTCCAAGAACAAGCAGAGCCCGGGCCACTGGCCCTTGCCCAAGG
CAGGGAAGAAGGATGTGTGTGTCCAGGAAGGAAAAAAAGGTGGATCAGTGATTTTACTTGAAAACAAGCTCCATCCCTTTTCTATATTTA
TAAGAAGAGAAGATCTTGAGTGAAGCAGCACGCGACCCAGGTGTGTGTGAATTGAATGGAGACGTTTCTTTTCTCTTTCTTTAATTTTTG
TTTTTGTTCTTTTTTTCTTTAAGGAAAGTTTTATTTTACTGTTCATTTTACTTTCTTGGTAACAAAAACTAAAATAAGGAATAGAAAAGC
TGTTTTTCAGGCTGACAGTCCAATTAAGGGTAGCCAAGACCTTGCATGGTAGAGTAGGAATCATAGTGTCAGTGAGGTCCCGTGAGTCTT
TGTGAGTCCTTGTGTCATCGTTCGGGCACTGTTTTTTTATGCAAGGGCAAAAATCTTTGTATCTGGGGAAAAAAAACTTTTTTTTAAATT
AAAAAGGAAAATAAAAGATATTGAGGTCTTCCTAGTGTTACTTAAATTAAGATCAAGGTAAGAAACATTGTAAAAAAAAATTACAAAAGT
GCTATTTGTTTCCTAAAAACAGTGATTTCTATTAAAAAGGTGTCAGAACTGGAGAAAATGCCGTGTAGTTATAATTTTTTAGCACAGACC
CTGCTGATCACGATGACATTTTGCCGTGTGTGTGTCTCTAGACTGGTGGGCCAGTCTCCTTGAAGGACAGAGGCGGAGCTCCCCACCCTT
CTCTCTCCTCAGAAAAGACCGTGCTCTCTTCTTGGTGCAGGGATCTTGTCTCCTGTTGTGAAGCCCAAATGGAAGCGTGGATGGTATCAG
GGCCCTACCCGTGGTCTTCTCAGATTCTGCTAGAGCAAAAGGCTGGTGCCTAAATAAGATCCCTTCCTTTGGTGCTGCTTTTGGTCTTTC
AGCCACCAGCATTATGAGTGCCTGGGGGACACCTCCGAGGGAACTGGCCAGCGGAGCTCTGTGGTGCGCACGCACCCTGGCCGTGACAGG
AGGGTGCGGGAGTACAGGCTGGCTGCATCAGCCCTTGGTGCTTAGAACAGAGGAGGAGTGACATGTTTTGAGGGTACGTCTCTGAGACAG
AGCCCCAGCGTGGCCTTCGCTCTGTCTTGCCTTTGGGGAGAGGTCTGAAGCTCCCACTCCTTTCTCTGCCTGTTGGCTCCAGGCACCAGA
AATTTACTCCACTCCACCCACCCACAAGCCTCCTGGGTGACCCTGGGCTAGAATTGCTGCGCTTGCCTCGGCTTGGCCGGTTGTGGCCTC
TCCTTGAGAAAACCAGGGTTGTGAAAGACTCAGACCATTCTCTCATCTTGCCTTGTCAGAAGTAAATTGTGTCAGATTTGTGCTCTCGCT
GGAGACCTTTGCCCCTTGCGTGCCCCTGGCCGATGGGAGGGCGGTGGAGGCTCTGTACCCTGGCCCTGCTGGAGCATCTCCCCCAAGCCC
ACTCCAGGCCCTGGGAATGGCCAGAGTCTAGGAGAGGTAGAAACGATCCTATCAGCTTCTCTCCCACCCAATTAGGCCCAGAGAGACAAA
GACAGATCTGAAAGCAAATGCAACAGAGAAGAGACACTTCTTAGAGTAAAATGTGTCTCATCTCTATCAGCCATCGCCTTTCATCTTCCC
AGGGGCCTCAGAAGAAGGAATTAAGTTAGGCTGAACAGGCCTCAGAGTTAGGCCCTGGCTGCTTGATTGGCTGAGGGGGAAAGAGTTCCC
TTTTCTCATTCAGAAACCAAGGTGCTGTGTCTAGTCAGGGAGCCTTGGAGATGCCTGGACTAGTTGGAGGAATCGTTGGCAGAGGATCAG
AGACCAGCAGCAGGCTGTCTGCCCTGTCTAGAGCTCTTCCCCTCAACTTGTCTGGGCCCATCTGGGGGTTGCCACACAACACCTAACTTA
CCTTTTCCTGAAAGAAGTTGGGAAACCATCATCACTAGAGGCCTTTGCTCAGAGAGGAGCTGCCTTAGGAGTCTTGGGTCGGAGGACGGG
GCTAGGAATTGACCAGGGCTTTGCCTGCCGCCCTCAGCAGTGTCGGGTACATTCTGACCTCGCCTGCAGCTGGGCTGTGGATTCTTCCTG
ACATTCAGATGTGAGCTGTTTTGGGAGTCAGCTAGTATGGAGTACGAGATGCAACCCAGCCCCCAAACCTACATTCTGCACTCAAATTCC
AAAACACTGCTTTACTGTAAAGAAGAGGCCCCTGGCACCCAATCTCCCTGTCCTTCACTGTCCCCTCAGACCTGGGCGGGGAGGGGGGGG
GGCCTGTGACCACCTGAGACATACGCTCGTGACACTGCCCCACCCCAGCCACCTCCACTTGCTTCCTCCTCCTTCCCTCCGCTGCTCTTT
CCCCACGGCCCAGAATTTAGCTGCTCTGACAGCCACTTTTGAGACCAGCTGGCTTTGTAGTCACTTCAGAGAGCTGGAGCGGCTGCCCAC
TGGGCCCTGACTGGGAGTCCCCTGCCAGCTCCTGATCAGGCGCTGCGCCCTGGTGGCAGTGATGACTGGGAGTCCCCTGCCAGCTCCTGT
CCAGGCGCTGCATCCTGGTAACAGTGAGGCCATGTTGCTGTCATCTCCACCTCTGCATTCTTGCTGCCTGTGGGTCCTTTTTCTTTCATG
GAGCCTGCTGGGTCTTGTCTCACCTGTGCTGAGCTCCTCTGGGGTTTTGATTTCTTCCTTCCTTATCAGGCCCTTTGGGGTAAGCCTGCT
GGTTGTACCTGACATAGGGAGGCAGTTAGGGGCAGTCCCTGGTGGGGCCGCCCTGGCAGCCTCCAGCTGGCACCATCGTGTGCCTGGTTT
CCCTGCAACACCTGCCTCTCTGTCCCTGCTGCTGCTTGGCTCAGGCCCAACAGGCAGCGTGCATGGAGGTGGTTACACACAGCTGTTTCC
GTGAGGGTGACCGTGTCTGCAGCACGCTTCCGTCTCCGCATGCACGGCTGCCTCTCCAGCCACCTCTGATACTTCTCTCTTGGGGCCATC
AGAGCCTCCCTTGGGCTGTCACCTCCCAGCTCACACACACTCTTCAGTGGTTTCCTCTCTTCATTCTCTTATAGGGCGTGGTCCTTCTTA
TTTATCTAAAGGGCTGAATTTAGGAGACTTTTTACCCAGGGGCAAAAGGCTCTTAGGGTAATGAGATGGATGGTGGCCCAGGTGCATTTT
CCAGGGCCTGGGTTCTCCAGATCCCGTGGCTTCTGTTGAGTGGAGGCAACTTTGCTCTGTGTGAACCTCGCCCCTGTCCCTCTGCCGGGC
ACCCCTGGCAGGAAGCAGGACTCCCATCCTCACCCTGACTTAGACTGTCCTCTGAGTCAGCTCCTCTCCAAGACAGGAGTGGGCAGCCCT
GGGCAGTCTTCTGGCCCCTTGCTAAAGTGAGGGGCAGGAAGCTGGGGCTGCCCTCCAGAAAGCCGGGGTAGGAACTCTGAAAAATACCTC
CTCTAAACGGAAGCAGGGCTCTCCAGTTCCACTTGGCGCCCCCTCCCACAAGGCCCTTCCTCCCTGAGGACCCCACCCCCCTACCCCTTC
CCCAGCAGCCTTTGGACCCTCACCTCTCTCCGGTGTCCGTGGGTCCTCAGCCCAGGGTGAGCTGCAGTCAGGCGGGATGGGACGGGCAGG
CCAGAGGTCAGCCAGCTCCTAGCAGAGAAGAGCCAGCCAGACCCCAACCCTGTCTCTTGTCCATGCCCTTTGTGATTTCAGTCTTGGTAG
ACTTGTATTTGGAGTTTTGTGCTTCAAAGTTTTTGTTTTTGTTTGTTTGGTTTTTGTTTTGAGGGGGTGGGGGGGGATACAGAGCAGCTG

>4671_4671_1_ANKRD28-PHF21A_ANKRD28_chr3_15836729_ENST00000383777_PHF21A_chr11_45975176_ENST00000257821_length(amino acids)=419AA_BP=70
MSRVCIVVLEEVEDESPAFISKLPQENKSLHSPPSGNVLVRYPSLVQAIFNGDPDEVRALIFKKEDVNFQTVKSHTETDEKQTESRTITP
PAAPKPKREENPQKLAFMVSLGLVTHDHLEEIQSKRQERKRRTTANPVYSGAVFEPERKKSAVTYLNSTMHPGTRKRGRPPKYNAVLGFG
ALTPTSPQSSHPDSPENEKTETTFTFPAPVQPVSLPSPTSTDGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPR
CQDQMLKKEEAIPWPGTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQEREQLEQKVKQLSNSISKCMEMKNTILARQKEMHSSLEKVKQL

--------------------------------------------------------------
>4671_4671_2_ANKRD28-PHF21A_ANKRD28_chr3_15836729_ENST00000383777_PHF21A_chr11_45975176_ENST00000323180_length(transcript)=2521nt_BP=210nt
ATGAGTCGAGTGTGTATTGTTGTTTTGGAGGAGGTAGAAGATGAATCTCCTGCATTCATTTCTAAATTGCCACAGGAAAATAAATCCCTA
CATTCTCCACCTTCTGGAAATGTATTGGTAAGATATCCATCACTGGTGCAAGCTATATTTAACGGAGATCCTGATGAAGTTCGAGCACTA
ATATTTAAGAAAGAAGATGTTAACTTTCAGACAGTTAAATCTCACACAGAAACAGATGAGAAACAAACAGAGAGCCGCACCATCACCCCA
CCTGCTGCACCCAAACCAAAACGGGAGGAGAACCCTCAGAAACTTGCCTTCATGGTGTCTCTAGGGTTGGTAACACATGACCATCTAGAA
GAAATCCAAAGCAAGAGGCAAGAGCGAAAAAGAAGAACAACAGCAAATCCGGTCTACAGTGGAGCAGTCTTTGAGCCAGAGCGTAAGAAG
AGTGCAGTGACATACCTAAACAGCACAATGCACCCTGGGACCCGGAAGAGAGCCAATGAGGAACACTGGCCAAAGGGTGATATTCATGAG
GATTTTTGCAGCGTTTGCAGAAAAAGTGGCCAGTTACTGATGTGCGACACATGTTCCCGTGTATATCATTTGGACTGCTTAGACCCCCCT
CTGAAAACAATTCCCAAGGGCATGTGGATCTGTCCCAGATGTCAGGACCAGATGCTGAAGAAGGAAGAAGCAATTCCATGGCCTGGAACT
TTAGCAATTGTTCATTCCTATATTGCCTACAAAGCAGCAAAAGAAGAAGAGAAACAGAAGTTACTTAAATGGAGTTCAGATTTAAAACAA
GAACGAGAACAACTAGAGCAAAAGGTGAAACAGCTCAGCAATTCCATAAGTAAATGCATGGAAATGAAGAACACCATCCTGGCCCGGCAG
AAGGAGATGCACAGCTCCCTGGAGAAGGTAAAACAGCTGATTCGCCTCATCCACGGCATCGACCTCTCCAAACCTGTAGACTCTGAGGCC
ACTGTGGGGGCCATCTCCAATGGCCCGGACTGCACCCCCCCTGCCAATGCCGCCACCTCCACGCCGGCCCCTTCCCCCTCCTCCCAGAGC
TGCACAGCGAACTGTAACCAGGGGGAAGAGACTAAATAACAGAGCCCCTCTAGGAGAAGCCACGGGATCCCGGCGGCAAGGAGAACAGAA
CACTGAAGACTCTAGAAAAGCAAAGCCGGATTTCTGGAAAGTGCAGAATTCTTTTGGTTCTTTGGTTCCAGAGAGAGAGAAGATGCTTGT
GCCAGGTGGCACCAGAGTTTGCCAATTGATCCTTCTTATTCTGTGTGTACATGCAAAGATTGGACCATGTTACATGAAATAGTGCCAGCT
GGAGGTTCTTTGCCAGCACCATGCCAAGTGAAATAATATATTTACTCTCTCTATTATACACCAGTGTGTGCCTGCAGCAGCCTCCACAGC
CACGATGGGTTTGTTTCTGTTTTCTTGGGTGGGGAGCAGGGACGGGCGGAGGGAGGAGAGCAGGTTTCAGATCCTTACTTGCCGAGCCGT
TTGTTTAGGTAGAGAAGACAAGTCCAAAGAGTGTGTGGGCTTTCCTGTTTCTAAACTTTCGCTACTATAAAACCAAAAAAAGGAATTGAG
ATTTCACCAACCCCAGTGCCCAGAAGAGGGAAGGGGAGTGGCTGGAGGGAGCAGGGGGTGGGACAGTGTATCAAATAAGCAGTATTTAAT
CACCTCTGGCGGGGGCCTCGTGCAAGGGGAGACTGACACCAAGAACAGCCAGTAGGTTCTTCTCCCCTGCACTCTGCTCCCTGCGCGGTA
ACCCCACCACTCCTGAAGCCTGCCCAGTCTCCTTCCTTCCCTGCTTGGTGAGTCGCGCATCTCCGTGGTTATCCCGCTGTCTCCTCTCCA
AGAACAAGCAGAGCCCGGGCCACTGGCCCTTGCCCAAGGCAGGGAAGAAGGATGTGTGTGTCCAGGAAGGAAAAAAAGGTGGATCAGTGA
TTTTACTTGAAAACAAGCTCCATCCCTTTTCTATATTTATAAGAAGAGAAGATCTTGAGTGAAGCAGCACGCGACCCAGGTGTGTGTGAA
TTGAATGGAGACGTTTCTTTTCTCTTTCTTTAATTTTTGTTTTTGTTCTTTTTTTCTTTAAGGAAAGTTTTATTTTACTGTTCATTTTAC
TTTCTTGGTAACAAAAACTAAAATAAGGAATAGAAAAGCTGTTTTTCAGGCTGACAGTCCAATTAAGGGTAGCCAAGACCTTGCATGGTA
GAGTAGGAATCATAGTGTCAGTGAGGTCCCGTGAGTCTTTGTGAGTCCTTGTGTCATCGTTCGGGCACTGTTTTTTTATGCAAGGGCAAA
AATCTTTGTATCTGGGGAAAAAAAACTTTTTTTTAAATTAAAAAGGAAAATAAAAGATATTGAGGTCTTCCTAGTGTTACTTAAATTAAG
ATCAAGGTAAGAAACATTGTAAAAAAAAATTACAAAAGTGCTATTTGTTTCCTAAAAACAGTGATTTCTATTAAAAAGGTGTCAGAACTG

>4671_4671_2_ANKRD28-PHF21A_ANKRD28_chr3_15836729_ENST00000383777_PHF21A_chr11_45975176_ENST00000323180_length(amino acids)=372AA_BP=70
MSRVCIVVLEEVEDESPAFISKLPQENKSLHSPPSGNVLVRYPSLVQAIFNGDPDEVRALIFKKEDVNFQTVKSHTETDEKQTESRTITP
PAAPKPKREENPQKLAFMVSLGLVTHDHLEEIQSKRQERKRRTTANPVYSGAVFEPERKKSAVTYLNSTMHPGTRKRANEEHWPKGDIHE
DFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKKEEAIPWPGTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQ
EREQLEQKVKQLSNSISKCMEMKNTILARQKEMHSSLEKVKQLIRLIHGIDLSKPVDSEATVGAISNGPDCTPPANAATSTPAPSPSSQS

--------------------------------------------------------------
>4671_4671_3_ANKRD28-PHF21A_ANKRD28_chr3_15836729_ENST00000383777_PHF21A_chr11_45975176_ENST00000418153_length(transcript)=1747nt_BP=210nt
ATGAGTCGAGTGTGTATTGTTGTTTTGGAGGAGGTAGAAGATGAATCTCCTGCATTCATTTCTAAATTGCCACAGGAAAATAAATCCCTA
CATTCTCCACCTTCTGGAAATGTATTGGTAAGATATCCATCACTGGTGCAAGCTATATTTAACGGAGATCCTGATGAAGTTCGAGCACTA
ATATTTAAGAAAGAAGATGTTAACTTTCAGACAGTTAAATCTCACACAGAAACAGATGAGAAACAAACAGAGAGCCGCACCATCACCCCA
CCTGCTGCACCCAAACCAAAACGGGAGGAGAACCCTCAGAAACTTGCCTTCATGGTGTCTCTAGGGTTGGTAACACATGACCATCTAGAA
GAAATCCAAAGCAAGAGGCAAGAGCGAAAAAGAAGAACAACAGCAAATCCGGTCTACAGTGGAGCAGTCTTTGAGCCAGAGCGTAAGAAG
AGTGCAGTGACATACCTAAACAGCACAATGCACCCTGGGACCCGGAAGAGAGGTCGTCCTCCAAAATACAATGCAGTGCTGGGGTTTGGA
GCCCTTACCCCAACATCCCCCCAATCCAGTCATCCTGACTCCCCTGAAAATGAAAAGACAGAGACCACATTCACTTTCCCTGCACCTGTT
CAGCCTGTGTCCCTGCCCAGCCCCACCTCCACAGACGGTGATATTCATGAGGATTTTTGCAGCGTTTGCAGAAAAAGTGGCCAGTTACTG
ATGTGCGACACATGTTCCCGTGTATATCATTTGGACTGCTTAGACCCCCCTCTGAAAACAATTCCCAAGGGCATGTGGATCTGTCCCAGA
TGTCAGGACCAGATGCTGAAGAAGGAAGAAGCAATTCCATGGCCTGGAACTTTAGCAATTGTTCATTCCTATATTGCCTACAAAGCAGCA
AAAGAAGAAGAGAAACAGAAGTTACTTAAATGGAGTTCAGATTTAAAACAAGAACGAGAACAACTAGAGCAAAAGGTGAAACAGCTCAGC
AATTCCATAAGTAAATGCATGGAAATGAAGAACACCATCCTGGCCCGGCAGAAGGAGATGCACAGCTCCCTGGAGAAGGTAAAACAGCTG
ATTCGCCTCATCCACGGCATCGACCTCTCCAAACCTGTAGACTCTGAGGCCACTGTGGGGGCCATCTCCAATGGCCCGGACTGCACCCCC
CCTGCCAATGCCGCCACCTCCACGCCGGCCCCTTCCCCCTCCTCCCAGAGCTGCACAGCGAACTGTAACCAGGGGGAAGAGACTAAATAA
CAGAGCCCCTCTAGGAGAAGCCACGGGATCCCGGCGGCAAGGAGAACAGAACACTGAAGACTCTAGAAAAGCAAAGCCGGATTTCTGGAA
AGTGCAGAATTCTTTTGGTTCTTTGGTTCCAGAGAGAGAGAAGATGCTTGTGCCAGGTGGCACCAGAGTTTGCCAATTGATCCTTCTTAT
TCTGTGTGTACATGCAAAGATTGGACCATGTTACATGAAATAGTGCCAGCTGGAGGTTCTTTGCCAGCACCATGCCAAGTGAAATAATAT
ATTTACTCTCTCTATTATACACCAGTGTGTGCCTGCAGCAGCCTCCACAGCCACGATGGGTTTGTTTCTGTTTTCTTGGGTGGGGAGCAG
GGACGGGCGGAGGGAGGAGAGCAGGTTTCAGATCCTTACTTGCCGAGCCGTTTGTTTAGGTAGAGAAGACAAGTCCAAAGAGTGTGTGGG

>4671_4671_3_ANKRD28-PHF21A_ANKRD28_chr3_15836729_ENST00000383777_PHF21A_chr11_45975176_ENST00000418153_length(amino acids)=419AA_BP=70
MSRVCIVVLEEVEDESPAFISKLPQENKSLHSPPSGNVLVRYPSLVQAIFNGDPDEVRALIFKKEDVNFQTVKSHTETDEKQTESRTITP
PAAPKPKREENPQKLAFMVSLGLVTHDHLEEIQSKRQERKRRTTANPVYSGAVFEPERKKSAVTYLNSTMHPGTRKRGRPPKYNAVLGFG
ALTPTSPQSSHPDSPENEKTETTFTFPAPVQPVSLPSPTSTDGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPR
CQDQMLKKEEAIPWPGTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQEREQLEQKVKQLSNSISKCMEMKNTILARQKEMHSSLEKVKQL

--------------------------------------------------------------
>4671_4671_4_ANKRD28-PHF21A_ANKRD28_chr3_15836729_ENST00000399451_PHF21A_chr11_45975176_ENST00000257821_length(transcript)=6177nt_BP=479nt
GCGGCCGCGGGGGCTGCCAGGGTATTTCGGGAAGGGGGCGTGAGGAGGCGGCGGCGGCAGCGGCGGGTAGGGCAGGCAGCAGAGGGAAGG
AGAAAGAAAGGAAGGAAGAGGGCGGGGAGTCCTCAGAGGAGGAGGCGGGACCGGCCGGGCACCTCACCTCTCGGCGGCGGCGGCGGCGGC
GGCGGCGGCGGGCGGCCGGGGAGGCGGCGCCGCCCCCTGCCCGCAGGTCTTCTCAGCGCAGTCGGCCGCGGACCCGCTGGTCCCGGGCAG
CGGCCAAGGCTACTGGGGCGGGAGCAGTGGGCCGGTCGGCGGCGGCAGCGGCAGCGGCGGAGGAGGAGGAGGCTGGAGTGGGCGCGGAGG
CGACCGCCATGGCGTTCCTCAAACTCCGTGACCAGCCATCACTGGTGCAAGCTATATTTAACGGAGATCCTGATGAAGTTCGAGCACTAA
TATTTAAGAAAGAAGATGTTAACTTTCAGACAGTTAAATCTCACACAGAAACAGATGAGAAACAAACAGAGAGCCGCACCATCACCCCAC
CTGCTGCACCCAAACCAAAACGGGAGGAGAACCCTCAGAAACTTGCCTTCATGGTGTCTCTAGGGTTGGTAACACATGACCATCTAGAAG
AAATCCAAAGCAAGAGGCAAGAGCGAAAAAGAAGAACAACAGCAAATCCGGTCTACAGTGGAGCAGTCTTTGAGCCAGAGCGTAAGAAGA
GTGCAGTGACATACCTAAACAGCACAATGCACCCTGGGACCCGGAAGAGAGGTCGTCCTCCAAAATACAATGCAGTGCTGGGGTTTGGAG
CCCTTACCCCAACATCCCCCCAATCCAGTCATCCTGACTCCCCTGAAAATGAAAAGACAGAGACCACATTCACTTTCCCTGCACCTGTTC
AGCCTGTGTCCCTGCCCAGCCCCACCTCCACAGACGGTGATATTCATGAGGATTTTTGCAGCGTTTGCAGAAAAAGTGGCCAGTTACTGA
TGTGCGACACATGTTCCCGTGTATATCATTTGGACTGCTTAGACCCCCCTCTGAAAACAATTCCCAAGGGCATGTGGATCTGTCCCAGAT
GTCAGGACCAGATGCTGAAGAAGGAAGAAGCAATTCCATGGCCTGGAACTTTAGCAATTGTTCATTCCTATATTGCCTACAAAGCAGCAA
AAGAAGAAGAGAAACAGAAGTTACTTAAATGGAGTTCAGATTTAAAACAAGAACGAGAACAACTAGAGCAAAAGGTGAAACAGCTCAGCA
ATTCCATAAGTAAATGCATGGAAATGAAGAACACCATCCTGGCCCGGCAGAAGGAGATGCACAGCTCCCTGGAGAAGGTAAAACAGCTGA
TTCGCCTCATCCACGGCATCGACCTCTCCAAACCTGTAGACTCTGAGGCCACTGTGGGGGCCATCTCCAATGGCCCGGACTGCACCCCCC
CTGCCAATGCCGCCACCTCCACGCCGGCCCCTTCCCCCTCCTCCCAGAGCTGCACAGCGAACTGTAACCAGGGGGAAGAGACTAAATAAC
AGAGCCCCTCTAGGAGAAGCCACGGGATCCCGGCGGCAAGGAGAACAGAACACTGAAGACTCTAGAAAAGCAAAGCCGGATTTCTGGAAA
GTGCAGAATTCTTTTGGTTCTTTGGTTCCAGAGAGAGAGAAGATGCTTGTGCCAGGTGGCACCAGAGTTTGCCAATTGATCCTTCTTATT
CTGTGTGTACATGCAAAGATTGGACCATGTTACATGAAATAGTGCCAGCTGGAGGTTCTTTGCCAGCACCATGCCAAGTGAAATAATATA
TTTACTCTCTCTATTATACACCAGTGTGTGCCTGCAGCAGCCTCCACAGCCACGATGGGTTTGTTTCTGTTTTCTTGGGTGGGGAGCAGG
GACGGGCGGAGGGAGGAGAGCAGGTTTCAGATCCTTACTTGCCGAGCCGTTTGTTTAGGTAGAGAAGACAAGTCCAAAGAGTGTGTGGGC
TTTCCTGTTTCTAAACTTTCGCTACTATAAAACCAAAAAAAGGAATTGAGATTTCACCAACCCCAGTGCCCAGAAGAGGGAAGGGGAGTG
GCTGGAGGGAGCAGGGGGTGGGACAGTGTATCAAATAAGCAGTATTTAATCACCTCTGGCGGGGGCCTCGTGCAAGGGGAGACTGACACC
AAGAACAGCCAGTAGGTTCTTCTCCCCTGCACTCTGCTCCCTGCGCGGTAACCCCACCACTCCTGAAGCCTGCCCAGTCTCCTTCCTTCC
CTGCTTGGTGAGTCGCGCATCTCCGTGGTTATCCCGCTGTCTCCTCTCCAAGAACAAGCAGAGCCCGGGCCACTGGCCCTTGCCCAAGGC
AGGGAAGAAGGATGTGTGTGTCCAGGAAGGAAAAAAAGGTGGATCAGTGATTTTACTTGAAAACAAGCTCCATCCCTTTTCTATATTTAT
AAGAAGAGAAGATCTTGAGTGAAGCAGCACGCGACCCAGGTGTGTGTGAATTGAATGGAGACGTTTCTTTTCTCTTTCTTTAATTTTTGT
TTTTGTTCTTTTTTTCTTTAAGGAAAGTTTTATTTTACTGTTCATTTTACTTTCTTGGTAACAAAAACTAAAATAAGGAATAGAAAAGCT
GTTTTTCAGGCTGACAGTCCAATTAAGGGTAGCCAAGACCTTGCATGGTAGAGTAGGAATCATAGTGTCAGTGAGGTCCCGTGAGTCTTT
GTGAGTCCTTGTGTCATCGTTCGGGCACTGTTTTTTTATGCAAGGGCAAAAATCTTTGTATCTGGGGAAAAAAAACTTTTTTTTAAATTA
AAAAGGAAAATAAAAGATATTGAGGTCTTCCTAGTGTTACTTAAATTAAGATCAAGGTAAGAAACATTGTAAAAAAAAATTACAAAAGTG
CTATTTGTTTCCTAAAAACAGTGATTTCTATTAAAAAGGTGTCAGAACTGGAGAAAATGCCGTGTAGTTATAATTTTTTAGCACAGACCC
TGCTGATCACGATGACATTTTGCCGTGTGTGTGTCTCTAGACTGGTGGGCCAGTCTCCTTGAAGGACAGAGGCGGAGCTCCCCACCCTTC
TCTCTCCTCAGAAAAGACCGTGCTCTCTTCTTGGTGCAGGGATCTTGTCTCCTGTTGTGAAGCCCAAATGGAAGCGTGGATGGTATCAGG
GCCCTACCCGTGGTCTTCTCAGATTCTGCTAGAGCAAAAGGCTGGTGCCTAAATAAGATCCCTTCCTTTGGTGCTGCTTTTGGTCTTTCA
GCCACCAGCATTATGAGTGCCTGGGGGACACCTCCGAGGGAACTGGCCAGCGGAGCTCTGTGGTGCGCACGCACCCTGGCCGTGACAGGA
GGGTGCGGGAGTACAGGCTGGCTGCATCAGCCCTTGGTGCTTAGAACAGAGGAGGAGTGACATGTTTTGAGGGTACGTCTCTGAGACAGA
GCCCCAGCGTGGCCTTCGCTCTGTCTTGCCTTTGGGGAGAGGTCTGAAGCTCCCACTCCTTTCTCTGCCTGTTGGCTCCAGGCACCAGAA
ATTTACTCCACTCCACCCACCCACAAGCCTCCTGGGTGACCCTGGGCTAGAATTGCTGCGCTTGCCTCGGCTTGGCCGGTTGTGGCCTCT
CCTTGAGAAAACCAGGGTTGTGAAAGACTCAGACCATTCTCTCATCTTGCCTTGTCAGAAGTAAATTGTGTCAGATTTGTGCTCTCGCTG
GAGACCTTTGCCCCTTGCGTGCCCCTGGCCGATGGGAGGGCGGTGGAGGCTCTGTACCCTGGCCCTGCTGGAGCATCTCCCCCAAGCCCA
CTCCAGGCCCTGGGAATGGCCAGAGTCTAGGAGAGGTAGAAACGATCCTATCAGCTTCTCTCCCACCCAATTAGGCCCAGAGAGACAAAG
ACAGATCTGAAAGCAAATGCAACAGAGAAGAGACACTTCTTAGAGTAAAATGTGTCTCATCTCTATCAGCCATCGCCTTTCATCTTCCCA
GGGGCCTCAGAAGAAGGAATTAAGTTAGGCTGAACAGGCCTCAGAGTTAGGCCCTGGCTGCTTGATTGGCTGAGGGGGAAAGAGTTCCCT
TTTCTCATTCAGAAACCAAGGTGCTGTGTCTAGTCAGGGAGCCTTGGAGATGCCTGGACTAGTTGGAGGAATCGTTGGCAGAGGATCAGA
GACCAGCAGCAGGCTGTCTGCCCTGTCTAGAGCTCTTCCCCTCAACTTGTCTGGGCCCATCTGGGGGTTGCCACACAACACCTAACTTAC
CTTTTCCTGAAAGAAGTTGGGAAACCATCATCACTAGAGGCCTTTGCTCAGAGAGGAGCTGCCTTAGGAGTCTTGGGTCGGAGGACGGGG
CTAGGAATTGACCAGGGCTTTGCCTGCCGCCCTCAGCAGTGTCGGGTACATTCTGACCTCGCCTGCAGCTGGGCTGTGGATTCTTCCTGA
CATTCAGATGTGAGCTGTTTTGGGAGTCAGCTAGTATGGAGTACGAGATGCAACCCAGCCCCCAAACCTACATTCTGCACTCAAATTCCA
AAACACTGCTTTACTGTAAAGAAGAGGCCCCTGGCACCCAATCTCCCTGTCCTTCACTGTCCCCTCAGACCTGGGCGGGGAGGGGGGGGG
GCCTGTGACCACCTGAGACATACGCTCGTGACACTGCCCCACCCCAGCCACCTCCACTTGCTTCCTCCTCCTTCCCTCCGCTGCTCTTTC
CCCACGGCCCAGAATTTAGCTGCTCTGACAGCCACTTTTGAGACCAGCTGGCTTTGTAGTCACTTCAGAGAGCTGGAGCGGCTGCCCACT
GGGCCCTGACTGGGAGTCCCCTGCCAGCTCCTGATCAGGCGCTGCGCCCTGGTGGCAGTGATGACTGGGAGTCCCCTGCCAGCTCCTGTC
CAGGCGCTGCATCCTGGTAACAGTGAGGCCATGTTGCTGTCATCTCCACCTCTGCATTCTTGCTGCCTGTGGGTCCTTTTTCTTTCATGG
AGCCTGCTGGGTCTTGTCTCACCTGTGCTGAGCTCCTCTGGGGTTTTGATTTCTTCCTTCCTTATCAGGCCCTTTGGGGTAAGCCTGCTG
GTTGTACCTGACATAGGGAGGCAGTTAGGGGCAGTCCCTGGTGGGGCCGCCCTGGCAGCCTCCAGCTGGCACCATCGTGTGCCTGGTTTC
CCTGCAACACCTGCCTCTCTGTCCCTGCTGCTGCTTGGCTCAGGCCCAACAGGCAGCGTGCATGGAGGTGGTTACACACAGCTGTTTCCG
TGAGGGTGACCGTGTCTGCAGCACGCTTCCGTCTCCGCATGCACGGCTGCCTCTCCAGCCACCTCTGATACTTCTCTCTTGGGGCCATCA
GAGCCTCCCTTGGGCTGTCACCTCCCAGCTCACACACACTCTTCAGTGGTTTCCTCTCTTCATTCTCTTATAGGGCGTGGTCCTTCTTAT
TTATCTAAAGGGCTGAATTTAGGAGACTTTTTACCCAGGGGCAAAAGGCTCTTAGGGTAATGAGATGGATGGTGGCCCAGGTGCATTTTC
CAGGGCCTGGGTTCTCCAGATCCCGTGGCTTCTGTTGAGTGGAGGCAACTTTGCTCTGTGTGAACCTCGCCCCTGTCCCTCTGCCGGGCA
CCCCTGGCAGGAAGCAGGACTCCCATCCTCACCCTGACTTAGACTGTCCTCTGAGTCAGCTCCTCTCCAAGACAGGAGTGGGCAGCCCTG
GGCAGTCTTCTGGCCCCTTGCTAAAGTGAGGGGCAGGAAGCTGGGGCTGCCCTCCAGAAAGCCGGGGTAGGAACTCTGAAAAATACCTCC
TCTAAACGGAAGCAGGGCTCTCCAGTTCCACTTGGCGCCCCCTCCCACAAGGCCCTTCCTCCCTGAGGACCCCACCCCCCTACCCCTTCC
CCAGCAGCCTTTGGACCCTCACCTCTCTCCGGTGTCCGTGGGTCCTCAGCCCAGGGTGAGCTGCAGTCAGGCGGGATGGGACGGGCAGGC
CAGAGGTCAGCCAGCTCCTAGCAGAGAAGAGCCAGCCAGACCCCAACCCTGTCTCTTGTCCATGCCCTTTGTGATTTCAGTCTTGGTAGA
CTTGTATTTGGAGTTTTGTGCTTCAAAGTTTTTGTTTTTGTTTGTTTGGTTTTTGTTTTGAGGGGGTGGGGGGGGATACAGAGCAGCTGA

>4671_4671_4_ANKRD28-PHF21A_ANKRD28_chr3_15836729_ENST00000399451_PHF21A_chr11_45975176_ENST00000257821_length(amino acids)=386AA_BP=37
MAFLKLRDQPSLVQAIFNGDPDEVRALIFKKEDVNFQTVKSHTETDEKQTESRTITPPAAPKPKREENPQKLAFMVSLGLVTHDHLEEIQ
SKRQERKRRTTANPVYSGAVFEPERKKSAVTYLNSTMHPGTRKRGRPPKYNAVLGFGALTPTSPQSSHPDSPENEKTETTFTFPAPVQPV
SLPSPTSTDGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKKEEAIPWPGTLAIVHSYIAYKAAKEE
EKQKLLKWSSDLKQEREQLEQKVKQLSNSISKCMEMKNTILARQKEMHSSLEKVKQLIRLIHGIDLSKPVDSEATVGAISNGPDCTPPAN

--------------------------------------------------------------
>4671_4671_5_ANKRD28-PHF21A_ANKRD28_chr3_15836729_ENST00000399451_PHF21A_chr11_45975176_ENST00000323180_length(transcript)=2790nt_BP=479nt
GCGGCCGCGGGGGCTGCCAGGGTATTTCGGGAAGGGGGCGTGAGGAGGCGGCGGCGGCAGCGGCGGGTAGGGCAGGCAGCAGAGGGAAGG
AGAAAGAAAGGAAGGAAGAGGGCGGGGAGTCCTCAGAGGAGGAGGCGGGACCGGCCGGGCACCTCACCTCTCGGCGGCGGCGGCGGCGGC
GGCGGCGGCGGGCGGCCGGGGAGGCGGCGCCGCCCCCTGCCCGCAGGTCTTCTCAGCGCAGTCGGCCGCGGACCCGCTGGTCCCGGGCAG
CGGCCAAGGCTACTGGGGCGGGAGCAGTGGGCCGGTCGGCGGCGGCAGCGGCAGCGGCGGAGGAGGAGGAGGCTGGAGTGGGCGCGGAGG
CGACCGCCATGGCGTTCCTCAAACTCCGTGACCAGCCATCACTGGTGCAAGCTATATTTAACGGAGATCCTGATGAAGTTCGAGCACTAA
TATTTAAGAAAGAAGATGTTAACTTTCAGACAGTTAAATCTCACACAGAAACAGATGAGAAACAAACAGAGAGCCGCACCATCACCCCAC
CTGCTGCACCCAAACCAAAACGGGAGGAGAACCCTCAGAAACTTGCCTTCATGGTGTCTCTAGGGTTGGTAACACATGACCATCTAGAAG
AAATCCAAAGCAAGAGGCAAGAGCGAAAAAGAAGAACAACAGCAAATCCGGTCTACAGTGGAGCAGTCTTTGAGCCAGAGCGTAAGAAGA
GTGCAGTGACATACCTAAACAGCACAATGCACCCTGGGACCCGGAAGAGAGCCAATGAGGAACACTGGCCAAAGGGTGATATTCATGAGG
ATTTTTGCAGCGTTTGCAGAAAAAGTGGCCAGTTACTGATGTGCGACACATGTTCCCGTGTATATCATTTGGACTGCTTAGACCCCCCTC
TGAAAACAATTCCCAAGGGCATGTGGATCTGTCCCAGATGTCAGGACCAGATGCTGAAGAAGGAAGAAGCAATTCCATGGCCTGGAACTT
TAGCAATTGTTCATTCCTATATTGCCTACAAAGCAGCAAAAGAAGAAGAGAAACAGAAGTTACTTAAATGGAGTTCAGATTTAAAACAAG
AACGAGAACAACTAGAGCAAAAGGTGAAACAGCTCAGCAATTCCATAAGTAAATGCATGGAAATGAAGAACACCATCCTGGCCCGGCAGA
AGGAGATGCACAGCTCCCTGGAGAAGGTAAAACAGCTGATTCGCCTCATCCACGGCATCGACCTCTCCAAACCTGTAGACTCTGAGGCCA
CTGTGGGGGCCATCTCCAATGGCCCGGACTGCACCCCCCCTGCCAATGCCGCCACCTCCACGCCGGCCCCTTCCCCCTCCTCCCAGAGCT
GCACAGCGAACTGTAACCAGGGGGAAGAGACTAAATAACAGAGCCCCTCTAGGAGAAGCCACGGGATCCCGGCGGCAAGGAGAACAGAAC
ACTGAAGACTCTAGAAAAGCAAAGCCGGATTTCTGGAAAGTGCAGAATTCTTTTGGTTCTTTGGTTCCAGAGAGAGAGAAGATGCTTGTG
CCAGGTGGCACCAGAGTTTGCCAATTGATCCTTCTTATTCTGTGTGTACATGCAAAGATTGGACCATGTTACATGAAATAGTGCCAGCTG
GAGGTTCTTTGCCAGCACCATGCCAAGTGAAATAATATATTTACTCTCTCTATTATACACCAGTGTGTGCCTGCAGCAGCCTCCACAGCC
ACGATGGGTTTGTTTCTGTTTTCTTGGGTGGGGAGCAGGGACGGGCGGAGGGAGGAGAGCAGGTTTCAGATCCTTACTTGCCGAGCCGTT
TGTTTAGGTAGAGAAGACAAGTCCAAAGAGTGTGTGGGCTTTCCTGTTTCTAAACTTTCGCTACTATAAAACCAAAAAAAGGAATTGAGA
TTTCACCAACCCCAGTGCCCAGAAGAGGGAAGGGGAGTGGCTGGAGGGAGCAGGGGGTGGGACAGTGTATCAAATAAGCAGTATTTAATC
ACCTCTGGCGGGGGCCTCGTGCAAGGGGAGACTGACACCAAGAACAGCCAGTAGGTTCTTCTCCCCTGCACTCTGCTCCCTGCGCGGTAA
CCCCACCACTCCTGAAGCCTGCCCAGTCTCCTTCCTTCCCTGCTTGGTGAGTCGCGCATCTCCGTGGTTATCCCGCTGTCTCCTCTCCAA
GAACAAGCAGAGCCCGGGCCACTGGCCCTTGCCCAAGGCAGGGAAGAAGGATGTGTGTGTCCAGGAAGGAAAAAAAGGTGGATCAGTGAT
TTTACTTGAAAACAAGCTCCATCCCTTTTCTATATTTATAAGAAGAGAAGATCTTGAGTGAAGCAGCACGCGACCCAGGTGTGTGTGAAT
TGAATGGAGACGTTTCTTTTCTCTTTCTTTAATTTTTGTTTTTGTTCTTTTTTTCTTTAAGGAAAGTTTTATTTTACTGTTCATTTTACT
TTCTTGGTAACAAAAACTAAAATAAGGAATAGAAAAGCTGTTTTTCAGGCTGACAGTCCAATTAAGGGTAGCCAAGACCTTGCATGGTAG
AGTAGGAATCATAGTGTCAGTGAGGTCCCGTGAGTCTTTGTGAGTCCTTGTGTCATCGTTCGGGCACTGTTTTTTTATGCAAGGGCAAAA
ATCTTTGTATCTGGGGAAAAAAAACTTTTTTTTAAATTAAAAAGGAAAATAAAAGATATTGAGGTCTTCCTAGTGTTACTTAAATTAAGA
TCAAGGTAAGAAACATTGTAAAAAAAAATTACAAAAGTGCTATTTGTTTCCTAAAAACAGTGATTTCTATTAAAAAGGTGTCAGAACTGG

>4671_4671_5_ANKRD28-PHF21A_ANKRD28_chr3_15836729_ENST00000399451_PHF21A_chr11_45975176_ENST00000323180_length(amino acids)=339AA_BP=37
MAFLKLRDQPSLVQAIFNGDPDEVRALIFKKEDVNFQTVKSHTETDEKQTESRTITPPAAPKPKREENPQKLAFMVSLGLVTHDHLEEIQ
SKRQERKRRTTANPVYSGAVFEPERKKSAVTYLNSTMHPGTRKRANEEHWPKGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKT
IPKGMWICPRCQDQMLKKEEAIPWPGTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQEREQLEQKVKQLSNSISKCMEMKNTILARQKEM

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>4671_4671_6_ANKRD28-PHF21A_ANKRD28_chr3_15836729_ENST00000399451_PHF21A_chr11_45975176_ENST00000418153_length(transcript)=2016nt_BP=479nt
GCGGCCGCGGGGGCTGCCAGGGTATTTCGGGAAGGGGGCGTGAGGAGGCGGCGGCGGCAGCGGCGGGTAGGGCAGGCAGCAGAGGGAAGG
AGAAAGAAAGGAAGGAAGAGGGCGGGGAGTCCTCAGAGGAGGAGGCGGGACCGGCCGGGCACCTCACCTCTCGGCGGCGGCGGCGGCGGC
GGCGGCGGCGGGCGGCCGGGGAGGCGGCGCCGCCCCCTGCCCGCAGGTCTTCTCAGCGCAGTCGGCCGCGGACCCGCTGGTCCCGGGCAG
CGGCCAAGGCTACTGGGGCGGGAGCAGTGGGCCGGTCGGCGGCGGCAGCGGCAGCGGCGGAGGAGGAGGAGGCTGGAGTGGGCGCGGAGG
CGACCGCCATGGCGTTCCTCAAACTCCGTGACCAGCCATCACTGGTGCAAGCTATATTTAACGGAGATCCTGATGAAGTTCGAGCACTAA
TATTTAAGAAAGAAGATGTTAACTTTCAGACAGTTAAATCTCACACAGAAACAGATGAGAAACAAACAGAGAGCCGCACCATCACCCCAC
CTGCTGCACCCAAACCAAAACGGGAGGAGAACCCTCAGAAACTTGCCTTCATGGTGTCTCTAGGGTTGGTAACACATGACCATCTAGAAG
AAATCCAAAGCAAGAGGCAAGAGCGAAAAAGAAGAACAACAGCAAATCCGGTCTACAGTGGAGCAGTCTTTGAGCCAGAGCGTAAGAAGA
GTGCAGTGACATACCTAAACAGCACAATGCACCCTGGGACCCGGAAGAGAGGTCGTCCTCCAAAATACAATGCAGTGCTGGGGTTTGGAG
CCCTTACCCCAACATCCCCCCAATCCAGTCATCCTGACTCCCCTGAAAATGAAAAGACAGAGACCACATTCACTTTCCCTGCACCTGTTC
AGCCTGTGTCCCTGCCCAGCCCCACCTCCACAGACGGTGATATTCATGAGGATTTTTGCAGCGTTTGCAGAAAAAGTGGCCAGTTACTGA
TGTGCGACACATGTTCCCGTGTATATCATTTGGACTGCTTAGACCCCCCTCTGAAAACAATTCCCAAGGGCATGTGGATCTGTCCCAGAT
GTCAGGACCAGATGCTGAAGAAGGAAGAAGCAATTCCATGGCCTGGAACTTTAGCAATTGTTCATTCCTATATTGCCTACAAAGCAGCAA
AAGAAGAAGAGAAACAGAAGTTACTTAAATGGAGTTCAGATTTAAAACAAGAACGAGAACAACTAGAGCAAAAGGTGAAACAGCTCAGCA
ATTCCATAAGTAAATGCATGGAAATGAAGAACACCATCCTGGCCCGGCAGAAGGAGATGCACAGCTCCCTGGAGAAGGTAAAACAGCTGA
TTCGCCTCATCCACGGCATCGACCTCTCCAAACCTGTAGACTCTGAGGCCACTGTGGGGGCCATCTCCAATGGCCCGGACTGCACCCCCC
CTGCCAATGCCGCCACCTCCACGCCGGCCCCTTCCCCCTCCTCCCAGAGCTGCACAGCGAACTGTAACCAGGGGGAAGAGACTAAATAAC
AGAGCCCCTCTAGGAGAAGCCACGGGATCCCGGCGGCAAGGAGAACAGAACACTGAAGACTCTAGAAAAGCAAAGCCGGATTTCTGGAAA
GTGCAGAATTCTTTTGGTTCTTTGGTTCCAGAGAGAGAGAAGATGCTTGTGCCAGGTGGCACCAGAGTTTGCCAATTGATCCTTCTTATT
CTGTGTGTACATGCAAAGATTGGACCATGTTACATGAAATAGTGCCAGCTGGAGGTTCTTTGCCAGCACCATGCCAAGTGAAATAATATA
TTTACTCTCTCTATTATACACCAGTGTGTGCCTGCAGCAGCCTCCACAGCCACGATGGGTTTGTTTCTGTTTTCTTGGGTGGGGAGCAGG
GACGGGCGGAGGGAGGAGAGCAGGTTTCAGATCCTTACTTGCCGAGCCGTTTGTTTAGGTAGAGAAGACAAGTCCAAAGAGTGTGTGGGC

>4671_4671_6_ANKRD28-PHF21A_ANKRD28_chr3_15836729_ENST00000399451_PHF21A_chr11_45975176_ENST00000418153_length(amino acids)=386AA_BP=37
MAFLKLRDQPSLVQAIFNGDPDEVRALIFKKEDVNFQTVKSHTETDEKQTESRTITPPAAPKPKREENPQKLAFMVSLGLVTHDHLEEIQ
SKRQERKRRTTANPVYSGAVFEPERKKSAVTYLNSTMHPGTRKRGRPPKYNAVLGFGALTPTSPQSSHPDSPENEKTETTFTFPAPVQPV
SLPSPTSTDGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKKEEAIPWPGTLAIVHSYIAYKAAKEE
EKQKLLKWSSDLKQEREQLEQKVKQLSNSISKCMEMKNTILARQKEMHSSLEKVKQLIRLIHGIDLSKPVDSEATVGAISNGPDCTPPAN

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Fusion Gene PPI Analysis for ANKRD28-PHF21A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ANKRD28-PHF21A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ANKRD28-PHF21A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC1832588Chromosome 11p11.2 Deletion Syndrome2GENOMICS_ENGLAND;ORPHANET
TgeneC0036421Systemic Scleroderma1GENOMICS_ENGLAND
TgeneC1849193PEELING SKIN SYNDROME1GENOMICS_ENGLAND
TgeneC3714756Intellectual Disability1GENOMICS_ENGLAND
TgeneC4721610Carcinoma, Ovarian Epithelial1CTD_human