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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CAMSAP2-CARS (FusionGDB2 ID:HG23271TG833)

Fusion Gene Summary for CAMSAP2-CARS

check button Fusion gene summary
Fusion gene informationFusion gene name: CAMSAP2-CARS
Fusion gene ID: hg23271tg833
HgeneTgene
Gene symbol

CAMSAP2

CARS

Gene ID

23271

833

Gene namecalmodulin regulated spectrin associated protein family member 2cysteinyl-tRNA synthetase 1
SynonymsCAMSAP1L1CARS|CYSRS|MGC:11246
Cytomap('CAMSAP1L1','CAMSAP2')('CARS','CARS')

1q32.1

11p15.4

Type of geneprotein-codingprotein-coding
Descriptioncalmodulin-regulated spectrin-associated protein 2calmodulin-regulated spectrin-associated protein 1-like protein 1cysteine--tRNA ligase, cytoplasmiccysteine tRNA ligase 1, cytoplasmiccysteine translase
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000236925, ENST00000358823, 
ENST00000413307, 
Fusion gene scores* DoF score10 X 9 X 5=45011 X 12 X 6=792
# samples 1012
** MAII scorelog2(10/450*10)=-2.16992500144231
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/792*10)=-2.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CAMSAP2 [Title/Abstract] AND CARS [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCAMSAP1L1(200824017)-CARS(3022478), # samples:1
CAMSAP2(200824017)-CARS(3022478), # samples:2
Anticipated loss of major functional domain due to fusion event.CAMSAP2-CARS seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CAMSAP2-CARS seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CAMSAP2-CARS seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CAMSAP2-CARS seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CAMSAP2-CARS seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CAMSAP2-CARS seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
CAMSAP2-CARS seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCAMSAP2

GO:0000226

microtubule cytoskeleton organization

24486153|24706919|24908486|27666745

HgeneCAMSAP2

GO:0031113

regulation of microtubule polymerization

24486153|24706919

HgeneCAMSAP2

GO:0050773

regulation of dendrite development

24908486

HgeneCAMSAP2

GO:0061564

axon development

24908486

HgeneCAMSAP2

GO:1903358

regulation of Golgi organization

27666745

TgeneCARS

GO:0006423

cysteinyl-tRNA aminoacylation

10908348|17303165


check buttonFusion gene breakpoints across CAMSAP2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CARS (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-43-8115-01ACAMSAP1L1chr1

200824017

-CARSchr11

3022478

-
ChimerDB4LUSCTCGA-43-8115-01ACAMSAP2chr1

200824017

+CARSchr11

3022478

-
ChimerDB4LUSCTCGA-43-8115CAMSAP2chr1

200824017

+CARSchr11

3022478

-


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Fusion Gene ORF analysis for CAMSAP2-CARS

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000236925ENST00000397114CAMSAP2chr1

200824017

+CARSchr11

3022478

-
5CDS-5UTRENST00000236925ENST00000401769CAMSAP2chr1

200824017

+CARSchr11

3022478

-
5CDS-5UTRENST00000236925ENST00000470221CAMSAP2chr1

200824017

+CARSchr11

3022478

-
5CDS-5UTRENST00000358823ENST00000397114CAMSAP2chr1

200824017

+CARSchr11

3022478

-
5CDS-5UTRENST00000358823ENST00000401769CAMSAP2chr1

200824017

+CARSchr11

3022478

-
5CDS-5UTRENST00000358823ENST00000470221CAMSAP2chr1

200824017

+CARSchr11

3022478

-
5CDS-5UTRENST00000413307ENST00000397114CAMSAP2chr1

200824017

+CARSchr11

3022478

-
5CDS-5UTRENST00000413307ENST00000401769CAMSAP2chr1

200824017

+CARSchr11

3022478

-
5CDS-5UTRENST00000413307ENST00000470221CAMSAP2chr1

200824017

+CARSchr11

3022478

-
Frame-shiftENST00000236925ENST00000278224CAMSAP2chr1

200824017

+CARSchr11

3022478

-
Frame-shiftENST00000236925ENST00000380525CAMSAP2chr1

200824017

+CARSchr11

3022478

-
Frame-shiftENST00000358823ENST00000278224CAMSAP2chr1

200824017

+CARSchr11

3022478

-
Frame-shiftENST00000358823ENST00000380525CAMSAP2chr1

200824017

+CARSchr11

3022478

-
Frame-shiftENST00000413307ENST00000278224CAMSAP2chr1

200824017

+CARSchr11

3022478

-
Frame-shiftENST00000413307ENST00000380525CAMSAP2chr1

200824017

+CARSchr11

3022478

-
In-frameENST00000236925ENST00000397111CAMSAP2chr1

200824017

+CARSchr11

3022478

-
In-frameENST00000358823ENST00000397111CAMSAP2chr1

200824017

+CARSchr11

3022478

-
In-frameENST00000413307ENST00000397111CAMSAP2chr1

200824017

+CARSchr11

3022478

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000358823CAMSAP2chr1200824017+ENST00000397111CARSchr113022478-4493416627042261318
ENST00000413307CAMSAP2chr1200824017+ENST00000397111CARSchr113022478-422438974939571302
ENST00000236925CAMSAP2chr1200824017+ENST00000397111CARSchr113022478-430539784940381329

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000358823ENST00000397111CAMSAP2chr1200824017+CARSchr113022478-0.0002927070.9997073
ENST00000413307ENST00000397111CAMSAP2chr1200824017+CARSchr113022478-0.0002914750.9997085
ENST00000236925ENST00000397111CAMSAP2chr1200824017+CARSchr113022478-0.0002008920.9997991

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Fusion Genomic Features for CAMSAP2-CARS


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for CAMSAP2-CARS


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:200824017/chr11:3022478)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000236925+15181166_123813091490.0Coiled coilOntology_term=ECO:0000255
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000236925+1518756_79313091490.0Coiled coilOntology_term=ECO:0000255
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000236925+1518887_92613091490.0Coiled coilOntology_term=ECO:0000255
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000358823+14171166_123812981479.0Coiled coilOntology_term=ECO:0000255
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000358823+1417756_79312981479.0Coiled coilOntology_term=ECO:0000255
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000358823+1417887_92612981479.0Coiled coilOntology_term=ECO:0000255
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000413307+14171166_123812821463.0Coiled coilOntology_term=ECO:0000255
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000413307+1417756_79312821463.0Coiled coilOntology_term=ECO:0000255
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000413307+1417887_92612821463.0Coiled coilOntology_term=ECO:0000255
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000236925+1518222_33513091490.0DomainCalponin-homology (CH)
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000358823+1417222_33512981479.0DomainCalponin-homology (CH)
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000413307+1417222_33512821463.0DomainCalponin-homology (CH)
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000236925+1518922_103413091490.0RegionMBD region
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000358823+1417922_103412981479.0RegionMBD region
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000413307+1417922_103412821463.0RegionMBD region

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000236925+15181349_148313091490.0DomainCKK
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000358823+14171349_148312981479.0DomainCKK
HgeneCAMSAP2chr1:200824017chr11:3022478ENST00000413307+14171349_148312821463.0DomainCKK
TgeneCARSchr1:200824017chr11:3022478ENST000002782242022406_410706727.0MotifNote='KMSKS' region
TgeneCARSchr1:200824017chr11:3022478ENST00000278224202257_67706727.0MotifNote='HIGH' region
TgeneCARSchr1:200824017chr11:3022478ENST000003805252123406_410787832.0MotifNote='KMSKS' region
TgeneCARSchr1:200824017chr11:3022478ENST00000380525212357_67787832.0MotifNote='HIGH' region
TgeneCARSchr1:200824017chr11:3022478ENST000003971112022406_410704749.0MotifNote='KMSKS' region
TgeneCARSchr1:200824017chr11:3022478ENST00000397111202257_67704749.0MotifNote='HIGH' region


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Fusion Gene Sequence for CAMSAP2-CARS


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>12741_12741_1_CAMSAP2-CARS_CAMSAP2_chr1_200824017_ENST00000236925_CARS_chr11_3022478_ENST00000397111_length(transcript)=4305nt_BP=3978nt
CGCCATGTGAAGGTTAGGGCCGGGACATCCCGAGGAGCCGCGGTGAAAGATGGGGGATGCTGCAGACCCCAGGGAGATGAGAAAGACGTT
CATTGTTCCAGCCATCAAGCCTTTTGACCACTATGATTTCTCCAGGGCCAAAATCGCCTGCAATCTGGCCTGGCTGGTGGCCAAAGCCTT
TGGGACAGAAAATGTGCCAGAGGAACTTCAAGAACCATTTTACACAGATCAGTATGACCAGGAACACATCAAACCACCTGTTGTTAATTT
GCTTCTATCGGCTGAACTATACTGTCGTGCTGGGAGTCTCATTCTCAAGAGTGATGCTGCAAAACCCCTTTTGGGCCATGATGCTGTAAT
CCAGGCTTTAGCACAGAAAGGTCTTTATGTCACTGACCAGGAAAAATTGGTAACTGAACGAGATCTCCACAAGAAACCCATACAGATGAG
TGCACATTTGGCCATGATCGATACCCTCATGATGGCTTATACTGTAGAAATGGTCAGTATAGAAAAAGTAATTGCGTGTGCTCAGCAGTA
TTCAGCTTTTTTTCAAGCCACAGATCTGCCCTATGATATTGAGGACGCTGTCATGTACTGGATAAATAAGGTAAATGAACATTTGAAAGA
CATAATGGAACAAGAACAAAAACTGAAAGAACATCACACAGTTGAAGCTCCAGGAGGTCAAAAGTCTCCTTCCAAATGGTTTTGGAAACT
GGTTCCAGCTCGTTATCGGAAAGAGCAAACATTGCTTAAGCAACTGCCTTGCATTCCATTGGTAGAAAATTTGTTGAAGGATGGGACAGA
TGGCTGTGCATTAGCTGCCCTTATTCATTTTTACTGTCCTGATGTTGTCAGATTAGAGGATATTTGTTTGAAAGAAACTATGTCTTTGGC
TGATAGCCTGTATAATCTGCAGCTGATTCAAGAATTTTGCCAAGAATACTTGAACCAGTGTTGCCATTTCACTCTGGAAGATATGCTCTA
TGCTGCTTCATCCATAAAGAGTAATTATTTGGTGTTCATGGCGGAACTGTTCTGGTGGTTTGAAGTGGTGAAGCCGTCTTTTGTACAGCC
TCGTGTTGTTCGTCCACAAGGAGCTGAACCTGTAAAAGATATGCCTTCAATTCCTGTCTTGAATGCTGCCAAAAGAAATGTCTTAGATAG
TAGTTCTGACTTCCCTTCAAGTGGGGAAGGAGCTACATTTACACAGTCTCATCATCATTTGCCTTCTAGGTATTCACGTCCCCAGGCTCA
TTCTTCAGCCTCAGGAGGAATTAGAAGGTCTTCATCTATGTCTTATGTTGATGGCTTCATAGGGACATGGCCCAAAGAGAAAAGATCATC
AGTGCATGGCGTATCATTTGATATTTCTTTTGATAAAGAAGATAGTGTACAGAGATCCACTCCAAACCGAGGAATCACTCGTTCTATTAG
TAATGAAGGACTTACTCTGAACAACAGTCATGTATCTAAACACATTAGGAAAAATTTGTCCTTCAAGCCAATAAATGGAGAAGAGGAAGC
AGAGAGCATTGAAGAAGAACTTAATATAGATTCTCACAGTGACCTCAAATCTTGTGTGCCCCTTAACACAAATGAACTAAATTCTAATGA
GAATATTCATTACAAGCTTCCAAATGGAGCTTTACAAAATAGAATACTTCTTGACGAGTTTGGCAATCAGATCGAGACACCAAGCATTGA
AGAAGCATTACAAATAATTCATGATACTGAAAAATCTCCTCATACACCTCAGCCAGACCAAATTGCTAATGGCTTCTTTCTTCATAGTCA
AGAAATGAGTATCTTAAATTCAAATATCAAGTTAAATCAATCTAGTCCTGATAATGTAACTGATACGAAAGGTGCCTTGAGTCCCATAAC
TGACAATACTGAAGTAGACACTGGAATTCACGTTCCTTCAGAAGATATTCCTGAAACTATGGACGAAGATTCTTCGTTGAGAGATTATAC
TGTAAGCTTGGACTCTGACATGGATGATGCATCTAAATTTCTTCAGGATTATGATATTCGAACTGGCAACACCAGGGAAGCTTTGAGTCC
TTGTCCAAGTACTGTAAGTACCAAGTCTCAGCCAGGCAGCAGTGCTTCTTCTAGTTCTGGAGTTAAAATGACCAGCTTTGCTGAACAAAA
ATTCAGGAAACTGAATCATACCGATGGAAAAAGTAGTGGAAGCAGTTCTCAAAAAACTACACCAGAAGGCTCTGAACTTAATATTCCTCA
TGTGGTTGCTTGGGCACAAATTCCAGAAGAAACAGGGCTTCCACAGGGACGGGACACTACCCAGCTGTTGGCCTCTGAAATGGTGCATCT
TAGGATGAAACTAGAAGAAAAGAGGCGTGCTATAGAAGCCCAGAAAAAGAAAATGGAAGCTGCTTTTACCAAACAGAGACAGAAAATGGG
AAGGACAGCATTCCTTACTGTAGTGAAAAAGAAAGGGGATGGGATATCTCCTCTACGAGAGGAAGCGGCGGGTGCAGAAGATGAGAAAGT
ATATACTGATCGAGCAAAAGAAAAGGAATCACAAAAAACTGATGGACAAAGGAGCAAGTCACTGGCAGATATAAAAGAGAGCATGGAGAA
TCCTCAAGCCAAATGGCTAAAGTCTCCAACTACACCTATTGATCCTGAGAAGCAGTGGAACCTGGCAAGCCCCTCAGAAGAAACTTTAAA
TGAAGGAGAGATTTTAGAATATACCAAATCCATTGAAAAGTTAAATTCATCCCTGCATTTTCTACAACAAGAAATGCAACGCTTGTCACT
TCAGCAGGAGATGTTAATGCAGATGAGAGAGCAACAATCTTGGGTGATTTCACCTCCACAACCCTCTCCACAGAAACAGATTCGAGATTT
TAAGCCTTCTAAGCAGGCAGGCCTGTCATCAGCCATTGCACCATTCTCCTCAGACTCCCCTCGTCCTACTCACCCATCTCCACAGTCTTC
TAACAGGAAAAGTGCATCTTTTTCTGTTAAAAGTCAAAGGACTCCTAGGCCAAATGAGTTAAAAATAACACCTTTGAATCGAACCTTGAC
ACCTCCTCGGTCTGTGGATAGCCTTCCTCGGTTAAGGAGGTTTTCACCAAGTCAAGTTCCTATTCAAACTAGGTCATTTGTATGTTTTGG
GGATGATGGAGAACCTCAGTTAAAGGAATCCAAACCTAAAGAGGAAGTTAAAAAGGAGGAATTGGAATCCAAAGGGACTTTGGAACAGCG
TGGACATAATCCAGAAGAAAAGGAAATCAAACCTTTTGAGTCAACAGTCTCTGAAGTCCTATCACTGCCTGTCACAGAGACTGTATGTCT
GACACCAAATGAGGACCAATTGAATCAACCCACAGAACCCCCTCCTAAACCCGTTTTCCCACCCACTGCTCCAAAAAATGTTAATCTGAT
TGAAGTTTCCCTCTCAGATTTGAAACCCCCTGAAAAGGCTGATGTACCTGTTGAAAAATATGATGGAGAAAGTGATAAAGAACAATTTGA
TGATGACCAGAAAGTATGCTGTGGATTCTTTTTTAAGGATGATCAAAAAGCAGAAAATGATATGGCAATGAAACGGGCAGCTTTGTTGGA
GAAAAGATTAAGAAGGGAAAAGGAAACTCAGCTCCGGAAACAACAGTTGGAAGCAGAAATGGAGCATAAGAAGGAGGAAACAAGGCGTAA
AACTGAGGAAGAACGTCAGAAGAAAGAAGATGAGAGAGCACGCAGAGAATTTATTAGGCAAGAATATATGAGGCGGAAACAACTGAAACT
AATGGAAGATATGGATACAGTAATTAAACCCCGTCCTCAAGTAGTAAAACAAAAAAAACAGCGACCAAAATCTATTCACAGAGATCATAT
TGAATCCCCCAAAACACCAATAAAGGGTCCTCCAGTCTCTAGCCTTTCTTTGGCATCGCTGAACACGGGTGATAACGAGAGTGTACATTC
AGGCAAGAGGACGCCAAGGGTCTGCCCACACATGACATGGAGGGCAAAGAGCTCAGCAAAGGGCAAGCCAAGAAGCTGAAGAAGCTCTTC
GAGGCTCAGGAGAAGCTCTACAAGGAATATCTGCAGATGGCCCAGAATGGAAGCTTCCAGTGAGGGGGCACAGGACTGACTTTTTAAACC
ATTGTGGACTAGTGGCTGCTGTCTGCCTCAGTGACAATGTCCCAGCGCTCCTATCATGTTTACAGTCACCCTTGGGTCCTAAATTAAGAG
TTGTGTTCATGTAGGTTCGTGTCGTCGTTGGCTCTGAGACATTGATAATAAATTTTTCTCAACAGTGAGACCCTC

>12741_12741_1_CAMSAP2-CARS_CAMSAP2_chr1_200824017_ENST00000236925_CARS_chr11_3022478_ENST00000397111_length(amino acids)=1329AA_BP=1309
MGDAADPREMRKTFIVPAIKPFDHYDFSRAKIACNLAWLVAKAFGTENVPEELQEPFYTDQYDQEHIKPPVVNLLLSAELYCRAGSLILK
SDAAKPLLGHDAVIQALAQKGLYVTDQEKLVTERDLHKKPIQMSAHLAMIDTLMMAYTVEMVSIEKVIACAQQYSAFFQATDLPYDIEDA
VMYWINKVNEHLKDIMEQEQKLKEHHTVEAPGGQKSPSKWFWKLVPARYRKEQTLLKQLPCIPLVENLLKDGTDGCALAALIHFYCPDVV
RLEDICLKETMSLADSLYNLQLIQEFCQEYLNQCCHFTLEDMLYAASSIKSNYLVFMAELFWWFEVVKPSFVQPRVVRPQGAEPVKDMPS
IPVLNAAKRNVLDSSSDFPSSGEGATFTQSHHHLPSRYSRPQAHSSASGGIRRSSSMSYVDGFIGTWPKEKRSSVHGVSFDISFDKEDSV
QRSTPNRGITRSISNEGLTLNNSHVSKHIRKNLSFKPINGEEEAESIEEELNIDSHSDLKSCVPLNTNELNSNENIHYKLPNGALQNRIL
LDEFGNQIETPSIEEALQIIHDTEKSPHTPQPDQIANGFFLHSQEMSILNSNIKLNQSSPDNVTDTKGALSPITDNTEVDTGIHVPSEDI
PETMDEDSSLRDYTVSLDSDMDDASKFLQDYDIRTGNTREALSPCPSTVSTKSQPGSSASSSSGVKMTSFAEQKFRKLNHTDGKSSGSSS
QKTTPEGSELNIPHVVAWAQIPEETGLPQGRDTTQLLASEMVHLRMKLEEKRRAIEAQKKKMEAAFTKQRQKMGRTAFLTVVKKKGDGIS
PLREEAAGAEDEKVYTDRAKEKESQKTDGQRSKSLADIKESMENPQAKWLKSPTTPIDPEKQWNLASPSEETLNEGEILEYTKSIEKLNS
SLHFLQQEMQRLSLQQEMLMQMREQQSWVISPPQPSPQKQIRDFKPSKQAGLSSAIAPFSSDSPRPTHPSPQSSNRKSASFSVKSQRTPR
PNELKITPLNRTLTPPRSVDSLPRLRRFSPSQVPIQTRSFVCFGDDGEPQLKESKPKEEVKKEELESKGTLEQRGHNPEEKEIKPFESTV
SEVLSLPVTETVCLTPNEDQLNQPTEPPPKPVFPPTAPKNVNLIEVSLSDLKPPEKADVPVEKYDGESDKEQFDDDQKVCCGFFFKDDQK
AENDMAMKRAALLEKRLRREKETQLRKQQLEAEMEHKKEETRRKTEEERQKKEDERARREFIRQEYMRRKQLKLMEDMDTVIKPRPQVVK
QKKQRPKSIHRDHIESPKTPIKGPPVSSLSLASLNTGDNESVHSGKRTPRVCPHMTWRAKSSAKGKPRS

--------------------------------------------------------------
>12741_12741_2_CAMSAP2-CARS_CAMSAP2_chr1_200824017_ENST00000358823_CARS_chr11_3022478_ENST00000397111_length(transcript)=4493nt_BP=4166nt
ACGGGGCGGACCTCGCGCGGACGGACGGACGGAGACGGCGCCGCCACATTCCTATGCCCGGGAGCGGCGGCGGCGGCGGCGGCGGCTCCC
GCGGGAGGCGGCAGGCGCGCGGCGCGGACAGCTGAGCTTCTCCTCCGTCGGCGCCCGGGCGGACATCGCCCGGGCCCCGATGGTTTGAGC
TTGCTTCTCCCTCCCTCCCGACCCCCGTGGTGGCGAGGCCACGCCATGTGAAGGTTAGGGCCGGGACATCCCGAGGAGCCGCGGTGAAAG
ATGGGGGATGCTGCAGACCCCAGGGAGATGAGAAAGACGTTCATTGTTCCAGCCATCAAGCCTTTTGACCACTATGATTTCTCCAGGGCC
AAAATCGCCTGCAATCTGGCCTGGCTGGTGGCCAAAGCCTTTGGGACAGAAAATGTGCCAGAGGAACTTCAAGAACCATTTTACACAGAT
CAGTATGACCAGGAACACATCAAACCACCTGTTGTTAATTTGCTTCTATCGGCTGAACTATACTGTCGTGCTGGGAGTCTCATTCTCAAG
AGTGATGCTGCAAAACCCCTTTTGGGCCATGATGCTGTAATCCAGGCTTTAGCACAGAAAGGTCTTTATGTCACTGACCAGGAAAAATTG
GTAACTGAACGAGATCTCCACAAGAAACCCATACAGATGAGTGCACATTTGGCCATGATCGATACCCTCATGATGGCTTATACTGTAGAA
ATGGTCAGTATAGAAAAAGTAATTGCGTGTGCTCAGCAGTATTCAGCTTTTTTTCAAGCCACAGATCTGCCCTATGATATTGAGGACGCT
GTCATGTACTGGATAAATAAGGTAAATGAACATTTGAAAGACATAATGGAACAAGAACAAAAACTGAAAGAACATCACACAGTTGAAGCT
CCAGGAGGTCAAAAGGCTCGTTATCGGAAAGAGCAAACATTGCTTAAGCAACTGCCTTGCATTCCATTGGTAGAAAATTTGTTGAAGGAT
GGGACAGATGGCTGTGCATTAGCTGCCCTTATTCATTTTTACTGTCCTGATGTTGTCAGATTAGAGGATATTTGTTTGAAAGAAACTATG
TCTTTGGCTGATAGCCTGTATAATCTGCAGCTGATTCAAGAATTTTGCCAAGAATACTTGAACCAGTGTTGCCATTTCACTCTGGAAGAT
ATGCTCTATGCTGCTTCATCCATAAAGAGTAATTATTTGGTGTTCATGGCGGAACTGTTCTGGTGGTTTGAAGTGGTGAAGCCGTCTTTT
GTACAGCCTCGTGTTGTTCGTCCACAAGGAGCTGAACCTGTAAAAGATATGCCTTCAATTCCTGTCTTGAATGCTGCCAAAAGAAATGTC
TTAGATAGTAGTTCTGACTTCCCTTCAAGTGGGGAAGGAGCTACATTTACACAGTCTCATCATCATTTGCCTTCTAGGTATTCACGTCCC
CAGGCTCATTCTTCAGCCTCAGGAGGAATTAGAAGGTCTTCATCTATGTCTTATGTTGATGGCTTCATAGGGACATGGCCCAAAGAGAAA
AGATCATCAGTGCATGGCGTATCATTTGATATTTCTTTTGATAAAGAAGATAGTGTACAGAGATCCACTCCAAACCGAGGAATCACTCGT
TCTATTAGTAATGAAGGACTTACTCTGAACAACAGTCATGTATCTAAACACATTAGGAAAAATTTGTCCTTCAAGCCAATAAATGGAGAA
GAGGAAGCAGAGAGCATTGAAGAAGAACTTAATATAGATTCTCACAGTGACCTCAAATCTTGTGTGCCCCTTAACACAAATGAACTAAAT
TCTAATGAGAATATTCATTACAAGCTTCCAAATGGAGCTTTACAAAATAGAATACTTCTTGACGAGTTTGGCAATCAGATCGAGACACCA
AGCATTGAAGAAGCATTACAAATAATTCATGATACTGAAAAATCTCCTCATACACCTCAGCCAGACCAAATTGCTAATGGCTTCTTTCTT
CATAGTCAAGAAATGAGTATCTTAAATTCAAATATCAAGTTAAATCAATCTAGTCCTGATAATGTAACTGATACGAAAGGTGCCTTGAGT
CCCATAACTGACAATACTGAAGTAGACACTGGAATTCACGTTCCTTCAGAAGATATTCCTGAAACTATGGACGAAGATTCTTCGTTGAGA
GATTATACTGTAAGCTTGGACTCTGACATGGATGATGCATCTAAATTTCTTCAGGATTATGATATTCGAACTGGCAACACCAGGGAAGCT
TTGAGTCCTTGTCCAAGTACTGTAAGTACCAAGTCTCAGCCAGGCAGCAGTGCTTCTTCTAGTTCTGGAGTTAAAATGACCAGCTTTGCT
GAACAAAAATTCAGGAAACTGAATCATACCGATGGAAAAAGTAGTGGAAGCAGTTCTCAAAAAACTACACCAGAAGGCTCTGAACTTAAT
ATTCCTCATGTGGTTGCTTGGGCACAAATTCCAGAAGAAACAGGGCTTCCACAGGGACGGGACACTACCCAGCTGTTGGCCTCTGAAATG
GTGCATCTTAGGATGAAACTAGAAGAAAAGAGGCGTGCTATAGAAGCCCAGAAAAAGAAAATGGAAGCTGCTTTTACCAAACAGAGACAG
AAAATGGGAAGGACAGCATTCCTTACTGTAGTGAAAAAGAAAGGGGATGGGATATCTCCTCTACGAGAGGAAGCGGCGGGTGCAGAAGAT
GAGAAAGTATATACTGATCGAGCAAAAGAAAAGGAATCACAAAAAACTGATGGACAAAGGAGCAAGTCACTGGCAGATATAAAAGAGAGC
ATGGAGAATCCTCAAGCCAAATGGCTAAAGTCTCCAACTACACCTATTGATCCTGAGAAGCAGTGGAACCTGGCAAGCCCCTCAGAAGAA
ACTTTAAATGAAGGAGAGATTTTAGAATATACCAAATCCATTGAAAAGTTAAATTCATCCCTGCATTTTCTACAACAAGAAATGCAACGC
TTGTCACTTCAGCAGGAGATGTTAATGCAGATGAGAGAGCAACAATCTTGGGTGATTTCACCTCCACAACCCTCTCCACAGAAACAGATT
CGAGATTTTAAGCCTTCTAAGCAGGCAGGCCTGTCATCAGCCATTGCACCATTCTCCTCAGACTCCCCTCGTCCTACTCACCCATCTCCA
CAGTCTTCTAACAGGAAAAGTGCATCTTTTTCTGTTAAAAGTCAAAGGACTCCTAGGCCAAATGAGTTAAAAATAACACCTTTGAATCGA
ACCTTGACACCTCCTCGGTCTGTGGATAGCCTTCCTCGGTTAAGGAGGTTTTCACCAAGTCAAGTTCCTATTCAAACTAGGTCATTTGTA
TGTTTTGGGGATGATGGAGAACCTCAGTTAAAGGAATCCAAACCTAAAGAGGAAGTTAAAAAGGAGGAATTGGAATCCAAAGGGACTTTG
GAACAGCGTGGACATAATCCAGAAGAAAAGGAAATCAAACCTTTTGAGTCAACAGTCTCTGAAGTCCTATCACTGCCTGTCACAGAGACT
GTATGTCTGACACCAAATGAGGACCAATTGAATCAACCCACAGAACCCCCTCCTAAACCCGTTTTCCCACCCACTGCTCCAAAAAATGTT
AATCTGATTGAAGTTTCCCTCTCAGATTTGAAACCCCCTGAAAAGGCTGATGTACCTGTTGAAAAATATGATGGAGAAAGTGATAAAGAA
CAATTTGATGATGACCAGAAAGTATGCTGTGGATTCTTTTTTAAGGATGATCAAAAAGCAGAAAATGATATGGCAATGAAACGGGCAGCT
TTGTTGGAGAAAAGATTAAGAAGGGAAAAGGAAACTCAGCTCCGGAAACAACAGTTGGAAGCAGAAATGGAGCATAAGAAGGAGGAAACA
AGGCGTAAAACTGAGGAAGAACGTCAGAAGAAAGAAGATGAGAGAGCACGCAGAGAATTTATTAGGCAAGAATATATGAGGCGGAAACAA
CTGAAACTAATGGAAGATATGGATACAGTAATTAAACCCCGTCCTCAAGTAGTAAAACAAAAAAAACAGCGACCAAAATCTATTCACAGA
GATCATATTGAATCCCCCAAAACACCAATAAAGGGTCCTCCAGTCTCTAGCCTTTCTTTGGCATCGCTGAACACGGGTGATAACGAGAGT
GTACATTCAGGCAAGAGGACGCCAAGGGTCTGCCCACACATGACATGGAGGGCAAAGAGCTCAGCAAAGGGCAAGCCAAGAAGCTGAAGA
AGCTCTTCGAGGCTCAGGAGAAGCTCTACAAGGAATATCTGCAGATGGCCCAGAATGGAAGCTTCCAGTGAGGGGGCACAGGACTGACTT
TTTAAACCATTGTGGACTAGTGGCTGCTGTCTGCCTCAGTGACAATGTCCCAGCGCTCCTATCATGTTTACAGTCACCCTTGGGTCCTAA
ATTAAGAGTTGTGTTCATGTAGGTTCGTGTCGTCGTTGGCTCTGAGACATTGATAATAAATTTTTCTCAACAGTGAGACCCTC

>12741_12741_2_CAMSAP2-CARS_CAMSAP2_chr1_200824017_ENST00000358823_CARS_chr11_3022478_ENST00000397111_length(amino acids)=1318AA_BP=1298
MGDAADPREMRKTFIVPAIKPFDHYDFSRAKIACNLAWLVAKAFGTENVPEELQEPFYTDQYDQEHIKPPVVNLLLSAELYCRAGSLILK
SDAAKPLLGHDAVIQALAQKGLYVTDQEKLVTERDLHKKPIQMSAHLAMIDTLMMAYTVEMVSIEKVIACAQQYSAFFQATDLPYDIEDA
VMYWINKVNEHLKDIMEQEQKLKEHHTVEAPGGQKARYRKEQTLLKQLPCIPLVENLLKDGTDGCALAALIHFYCPDVVRLEDICLKETM
SLADSLYNLQLIQEFCQEYLNQCCHFTLEDMLYAASSIKSNYLVFMAELFWWFEVVKPSFVQPRVVRPQGAEPVKDMPSIPVLNAAKRNV
LDSSSDFPSSGEGATFTQSHHHLPSRYSRPQAHSSASGGIRRSSSMSYVDGFIGTWPKEKRSSVHGVSFDISFDKEDSVQRSTPNRGITR
SISNEGLTLNNSHVSKHIRKNLSFKPINGEEEAESIEEELNIDSHSDLKSCVPLNTNELNSNENIHYKLPNGALQNRILLDEFGNQIETP
SIEEALQIIHDTEKSPHTPQPDQIANGFFLHSQEMSILNSNIKLNQSSPDNVTDTKGALSPITDNTEVDTGIHVPSEDIPETMDEDSSLR
DYTVSLDSDMDDASKFLQDYDIRTGNTREALSPCPSTVSTKSQPGSSASSSSGVKMTSFAEQKFRKLNHTDGKSSGSSSQKTTPEGSELN
IPHVVAWAQIPEETGLPQGRDTTQLLASEMVHLRMKLEEKRRAIEAQKKKMEAAFTKQRQKMGRTAFLTVVKKKGDGISPLREEAAGAED
EKVYTDRAKEKESQKTDGQRSKSLADIKESMENPQAKWLKSPTTPIDPEKQWNLASPSEETLNEGEILEYTKSIEKLNSSLHFLQQEMQR
LSLQQEMLMQMREQQSWVISPPQPSPQKQIRDFKPSKQAGLSSAIAPFSSDSPRPTHPSPQSSNRKSASFSVKSQRTPRPNELKITPLNR
TLTPPRSVDSLPRLRRFSPSQVPIQTRSFVCFGDDGEPQLKESKPKEEVKKEELESKGTLEQRGHNPEEKEIKPFESTVSEVLSLPVTET
VCLTPNEDQLNQPTEPPPKPVFPPTAPKNVNLIEVSLSDLKPPEKADVPVEKYDGESDKEQFDDDQKVCCGFFFKDDQKAENDMAMKRAA
LLEKRLRREKETQLRKQQLEAEMEHKKEETRRKTEEERQKKEDERARREFIRQEYMRRKQLKLMEDMDTVIKPRPQVVKQKKQRPKSIHR
DHIESPKTPIKGPPVSSLSLASLNTGDNESVHSGKRTPRVCPHMTWRAKSSAKGKPRS

--------------------------------------------------------------
>12741_12741_3_CAMSAP2-CARS_CAMSAP2_chr1_200824017_ENST00000413307_CARS_chr11_3022478_ENST00000397111_length(transcript)=4224nt_BP=3897nt
CGCCATGTGAAGGTTAGGGCCGGGACATCCCGAGGAGCCGCGGTGAAAGATGGGGGATGCTGCAGACCCCAGGGAGATGAGAAAGACGTT
CATTGTTCCAGCCATCAAGCCTTTTGACCACTATGATTTCTCCAGGGCCAAAATCGCCTGCAATCTGGCCTGGCTGGTGGCCAAAGCCTT
TGGGACAGAAAATGTGCCAGAGGAACTTCAAGAACCATTTTACACAGATCAGTATGACCAGGAACACATCAAACCACCTGTTGTTAATTT
GCTTCTATCGGCTGAACTATACTGTCGTGCTGGGAGTCTCATTCTCAAGAGTGATGCTGCAAAACCCCTTTTGGGCCATGATGCTGTAAT
CCAGGCTTTAGCACAGAAAGGTCTTTATGTCACTGACCAGGAAAAATTGGTAACTGAACGAGATCTCCACAAGAAACCCATACAGATGAG
TGCACATTTGGCCATGATCGATACCCTCATGATGGCTTATACTGTAGAAATGGTCAGTATAGAAAAAGTAATTGCGTGTGCTCAGCAGTA
TTCAGCTTTTTTTCAAGCCACAGATCTGCCCTATGATATTGAGGACGCTGTCATGTACTGGATAAATAAGGTAAATGAACATTTGAAAGA
CATAATGGAACAAGAACAAAAACTGAAAGAACATCACACAGTTGAAGCTCCAGGAGGTCAAAAGGCTCGTTATCGGAAAGAGCAAACATT
GCTTAAGCAACTGCCTTGCATTCCATTGGTAGAAAATTTGTTGAAGGATGGGACAGATGGCTGTGCATTAGCTGCCCTTATTCATTTTTA
CTGTCCTGATGTTGTCAGATTAGAGGATATTTGTTTGAAAGAAACTATGTCTTTGGCTGATAGCCTGTATAATCTGCAGCTGATTCAAGA
ATTTTGCCAAGAATACTTGAACCAGTGTTGCCATTTCACTCTGGAAGATATGCTCTATGCTGCTTCATCCATAAAGAGTAATTATTTGGT
GTTCATGGCGGAACTGTTCTGGTGGTTTGAAGTGGTGAAGCCGTCTTTTGTACAGCCTCGTGTTGTTCGTCCACAAGGAGCTGAACCTGT
AAAAGATATGCCTTCAATTCCTGTCTTGAATGCTGCCAAAAGAAATGTCTTAGATAGTAGTTCTGACTTCCCTTCAAGGTATTCACGTCC
CCAGGCTCATTCTTCAGCCTCAGGAGGAATTAGAAGGTCTTCATCTATGTCTTATGTTGATGGCTTCATAGGGACATGGCCCAAAGAGAA
AAGATCATCAGTGCATGGCGTATCATTTGATATTTCTTTTGATAAAGAAGATAGTGTACAGAGATCCACTCCAAACCGAGGAATCACTCG
TTCTATTAGTAATGAAGGACTTACTCTGAACAACAGTCATGTATCTAAACACATTAGGAAAAATTTGTCCTTCAAGCCAATAAATGGAGA
AGAGGAAGCAGAGAGCATTGAAGAAGAACTTAATATAGATTCTCACAGTGACCTCAAATCTTGTGTGCCCCTTAACACAAATGAACTAAA
TTCTAATGAGAATATTCATTACAAGCTTCCAAATGGAGCTTTACAAAATAGAATACTTCTTGACGAGTTTGGCAATCAGATCGAGACACC
AAGCATTGAAGAAGCATTACAAATAATTCATGATACTGAAAAATCTCCTCATACACCTCAGCCAGACCAAATTGCTAATGGCTTCTTTCT
TCATAGTCAAGAAATGAGTATCTTAAATTCAAATATCAAGTTAAATCAATCTAGTCCTGATAATGTAACTGATACGAAAGGTGCCTTGAG
TCCCATAACTGACAATACTGAAGTAGACACTGGAATTCACGTTCCTTCAGAAGATATTCCTGAAACTATGGACGAAGATTCTTCGTTGAG
AGATTATACTGTAAGCTTGGACTCTGACATGGATGATGCATCTAAATTTCTTCAGGATTATGATATTCGAACTGGCAACACCAGGGAAGC
TTTGAGTCCTTGTCCAAGTACTGTAAGTACCAAGTCTCAGCCAGGCAGCAGTGCTTCTTCTAGTTCTGGAGTTAAAATGACCAGCTTTGC
TGAACAAAAATTCAGGAAACTGAATCATACCGATGGAAAAAGTAGTGGAAGCAGTTCTCAAAAAACTACACCAGAAGGCTCTGAACTTAA
TATTCCTCATGTGGTTGCTTGGGCACAAATTCCAGAAGAAACAGGGCTTCCACAGGGACGGGACACTACCCAGCTGTTGGCCTCTGAAAT
GGTGCATCTTAGGATGAAACTAGAAGAAAAGAGGCGTGCTATAGAAGCCCAGAAAAAGAAAATGGAAGCTGCTTTTACCAAACAGAGACA
GAAAATGGGAAGGACAGCATTCCTTACTGTAGTGAAAAAGAAAGGGGATGGGATATCTCCTCTACGAGAGGAAGCGGCGGGTGCAGAAGA
TGAGAAAGTATATACTGATCGAGCAAAAGAAAAGGAATCACAAAAAACTGATGGACAAAGGAGCAAGTCACTGGCAGATATAAAAGAGAG
CATGGAGAATCCTCAAGCCAAATGGCTAAAGTCTCCAACTACACCTATTGATCCTGAGAAGCAGTGGAACCTGGCAAGCCCCTCAGAAGA
AACTTTAAATGAAGGAGAGATTTTAGAATATACCAAATCCATTGAAAAGTTAAATTCATCCCTGCATTTTCTACAACAAGAAATGCAACG
CTTGTCACTTCAGCAGGAGATGTTAATGCAGATGAGAGAGCAACAATCTTGGGTGATTTCACCTCCACAACCCTCTCCACAGAAACAGAT
TCGAGATTTTAAGCCTTCTAAGCAGGCAGGCCTGTCATCAGCCATTGCACCATTCTCCTCAGACTCCCCTCGTCCTACTCACCCATCTCC
ACAGTCTTCTAACAGGAAAAGTGCATCTTTTTCTGTTAAAAGTCAAAGGACTCCTAGGCCAAATGAGTTAAAAATAACACCTTTGAATCG
AACCTTGACACCTCCTCGGTCTGTGGATAGCCTTCCTCGGTTAAGGAGGTTTTCACCAAGTCAAGTTCCTATTCAAACTAGGTCATTTGT
ATGTTTTGGGGATGATGGAGAACCTCAGTTAAAGGAATCCAAACCTAAAGAGGAAGTTAAAAAGGAGGAATTGGAATCCAAAGGGACTTT
GGAACAGCGTGGACATAATCCAGAAGAAAAGGAAATCAAACCTTTTGAGTCAACAGTCTCTGAAGTCCTATCACTGCCTGTCACAGAGAC
TGTATGTCTGACACCAAATGAGGACCAATTGAATCAACCCACAGAACCCCCTCCTAAACCCGTTTTCCCACCCACTGCTCCAAAAAATGT
TAATCTGATTGAAGTTTCCCTCTCAGATTTGAAACCCCCTGAAAAGGCTGATGTACCTGTTGAAAAATATGATGGAGAAAGTGATAAAGA
ACAATTTGATGATGACCAGAAAGTATGCTGTGGATTCTTTTTTAAGGATGATCAAAAAGCAGAAAATGATATGGCAATGAAACGGGCAGC
TTTGTTGGAGAAAAGATTAAGAAGGGAAAAGGAAACTCAGCTCCGGAAACAACAGTTGGAAGCAGAAATGGAGCATAAGAAGGAGGAAAC
AAGGCGTAAAACTGAGGAAGAACGTCAGAAGAAAGAAGATGAGAGAGCACGCAGAGAATTTATTAGGCAAGAATATATGAGGCGGAAACA
ACTGAAACTAATGGAAGATATGGATACAGTAATTAAACCCCGTCCTCAAGTAGTAAAACAAAAAAAACAGCGACCAAAATCTATTCACAG
AGATCATATTGAATCCCCCAAAACACCAATAAAGGGTCCTCCAGTCTCTAGCCTTTCTTTGGCATCGCTGAACACGGGTGATAACGAGAG
TGTACATTCAGGCAAGAGGACGCCAAGGGTCTGCCCACACATGACATGGAGGGCAAAGAGCTCAGCAAAGGGCAAGCCAAGAAGCTGAAG
AAGCTCTTCGAGGCTCAGGAGAAGCTCTACAAGGAATATCTGCAGATGGCCCAGAATGGAAGCTTCCAGTGAGGGGGCACAGGACTGACT
TTTTAAACCATTGTGGACTAGTGGCTGCTGTCTGCCTCAGTGACAATGTCCCAGCGCTCCTATCATGTTTACAGTCACCCTTGGGTCCTA
AATTAAGAGTTGTGTTCATGTAGGTTCGTGTCGTCGTTGGCTCTGAGACATTGATAATAAATTTTTCTCAACAGTGAGACCCTC

>12741_12741_3_CAMSAP2-CARS_CAMSAP2_chr1_200824017_ENST00000413307_CARS_chr11_3022478_ENST00000397111_length(amino acids)=1302AA_BP=1282
MGDAADPREMRKTFIVPAIKPFDHYDFSRAKIACNLAWLVAKAFGTENVPEELQEPFYTDQYDQEHIKPPVVNLLLSAELYCRAGSLILK
SDAAKPLLGHDAVIQALAQKGLYVTDQEKLVTERDLHKKPIQMSAHLAMIDTLMMAYTVEMVSIEKVIACAQQYSAFFQATDLPYDIEDA
VMYWINKVNEHLKDIMEQEQKLKEHHTVEAPGGQKARYRKEQTLLKQLPCIPLVENLLKDGTDGCALAALIHFYCPDVVRLEDICLKETM
SLADSLYNLQLIQEFCQEYLNQCCHFTLEDMLYAASSIKSNYLVFMAELFWWFEVVKPSFVQPRVVRPQGAEPVKDMPSIPVLNAAKRNV
LDSSSDFPSRYSRPQAHSSASGGIRRSSSMSYVDGFIGTWPKEKRSSVHGVSFDISFDKEDSVQRSTPNRGITRSISNEGLTLNNSHVSK
HIRKNLSFKPINGEEEAESIEEELNIDSHSDLKSCVPLNTNELNSNENIHYKLPNGALQNRILLDEFGNQIETPSIEEALQIIHDTEKSP
HTPQPDQIANGFFLHSQEMSILNSNIKLNQSSPDNVTDTKGALSPITDNTEVDTGIHVPSEDIPETMDEDSSLRDYTVSLDSDMDDASKF
LQDYDIRTGNTREALSPCPSTVSTKSQPGSSASSSSGVKMTSFAEQKFRKLNHTDGKSSGSSSQKTTPEGSELNIPHVVAWAQIPEETGL
PQGRDTTQLLASEMVHLRMKLEEKRRAIEAQKKKMEAAFTKQRQKMGRTAFLTVVKKKGDGISPLREEAAGAEDEKVYTDRAKEKESQKT
DGQRSKSLADIKESMENPQAKWLKSPTTPIDPEKQWNLASPSEETLNEGEILEYTKSIEKLNSSLHFLQQEMQRLSLQQEMLMQMREQQS
WVISPPQPSPQKQIRDFKPSKQAGLSSAIAPFSSDSPRPTHPSPQSSNRKSASFSVKSQRTPRPNELKITPLNRTLTPPRSVDSLPRLRR
FSPSQVPIQTRSFVCFGDDGEPQLKESKPKEEVKKEELESKGTLEQRGHNPEEKEIKPFESTVSEVLSLPVTETVCLTPNEDQLNQPTEP
PPKPVFPPTAPKNVNLIEVSLSDLKPPEKADVPVEKYDGESDKEQFDDDQKVCCGFFFKDDQKAENDMAMKRAALLEKRLRREKETQLRK
QQLEAEMEHKKEETRRKTEEERQKKEDERARREFIRQEYMRRKQLKLMEDMDTVIKPRPQVVKQKKQRPKSIHRDHIESPKTPIKGPPVS
SLSLASLNTGDNESVHSGKRTPRVCPHMTWRAKSSAKGKPRS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CAMSAP2-CARS


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CAMSAP2-CARS


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CAMSAP2-CARS


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource