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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CLEC16A-ATF7IP2 (FusionGDB2 ID:HG23274TG80063)

Fusion Gene Summary for CLEC16A-ATF7IP2

check button Fusion gene summary
Fusion gene informationFusion gene name: CLEC16A-ATF7IP2
Fusion gene ID: hg23274tg80063
HgeneTgene
Gene symbol

CLEC16A

ATF7IP2

Gene ID

23274

80063

Gene nameC-type lectin domain containing 16Aactivating transcription factor 7 interacting protein 2
SynonymsGop-1|KIAA0350MCAF2
Cytomap('CLEC16A')('ATF7IP2')

16p13.13

16p13.2-p13.13

Type of geneprotein-codingprotein-coding
Descriptionprotein CLEC16AC-type lectin domain family 16 member Aactivating transcription factor 7-interacting protein 2ATF7-interacting protein 2MBD1-containing chromatin associated factor 2
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000465491, ENST00000409552, 
ENST00000409790, ENST00000381822, 
Fusion gene scores* DoF score13 X 9 X 9=10533 X 5 X 3=45
# samples 165
** MAII scorelog2(16/1053*10)=-2.71836162613835
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/45*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: CLEC16A [Title/Abstract] AND ATF7IP2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCLEC16A(11154879)-ATF7IP2(10574736), # samples:2
Anticipated loss of major functional domain due to fusion event.CLEC16A-ATF7IP2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CLEC16A-ATF7IP2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CLEC16A-ATF7IP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CLEC16A-ATF7IP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CLEC16A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ATF7IP2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-JY-A6FHCLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
ChimerDB4STADTCGA-VQ-A8PE-01ACLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
ChimerDB4STADTCGA-VQ-A8PECLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+


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Fusion Gene ORF analysis for CLEC16A-ATF7IP2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000465491ENST00000396559CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
3UTR-3CDSENST00000465491ENST00000396559CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
3UTR-3CDSENST00000465491ENST00000396560CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
3UTR-3CDSENST00000465491ENST00000396560CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
3UTR-intronENST00000465491ENST00000324570CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
3UTR-intronENST00000465491ENST00000324570CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
3UTR-intronENST00000465491ENST00000356427CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
3UTR-intronENST00000465491ENST00000356427CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
3UTR-intronENST00000465491ENST00000543967CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
3UTR-intronENST00000465491ENST00000543967CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
3UTR-intronENST00000465491ENST00000561932CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
3UTR-intronENST00000465491ENST00000561932CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
5CDS-5UTRENST00000409552ENST00000324570CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
5CDS-5UTRENST00000409552ENST00000356427CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
5CDS-5UTRENST00000409552ENST00000543967CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
5CDS-5UTRENST00000409790ENST00000324570CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
5CDS-5UTRENST00000409790ENST00000356427CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
5CDS-5UTRENST00000409790ENST00000543967CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
5CDS-intronENST00000409552ENST00000324570CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
5CDS-intronENST00000409552ENST00000324570CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
5CDS-intronENST00000409552ENST00000356427CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
5CDS-intronENST00000409552ENST00000356427CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
5CDS-intronENST00000409552ENST00000543967CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
5CDS-intronENST00000409552ENST00000543967CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
5CDS-intronENST00000409552ENST00000561932CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
5CDS-intronENST00000409552ENST00000561932CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
5CDS-intronENST00000409552ENST00000561932CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
5CDS-intronENST00000409790ENST00000324570CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
5CDS-intronENST00000409790ENST00000324570CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
5CDS-intronENST00000409790ENST00000356427CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
5CDS-intronENST00000409790ENST00000356427CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
5CDS-intronENST00000409790ENST00000543967CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
5CDS-intronENST00000409790ENST00000543967CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
5CDS-intronENST00000409790ENST00000561932CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
5CDS-intronENST00000409790ENST00000561932CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
5CDS-intronENST00000409790ENST00000561932CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
5UTR-3CDSENST00000381822ENST00000396559CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
5UTR-3CDSENST00000381822ENST00000396560CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
5UTR-5UTRENST00000381822ENST00000324570CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
5UTR-5UTRENST00000381822ENST00000356427CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
5UTR-5UTRENST00000381822ENST00000543967CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
5UTR-intronENST00000381822ENST00000561932CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
Frame-shiftENST00000409552ENST00000396559CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
Frame-shiftENST00000409552ENST00000396559CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
Frame-shiftENST00000409552ENST00000396559CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
Frame-shiftENST00000409552ENST00000396560CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
Frame-shiftENST00000409790ENST00000396559CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
Frame-shiftENST00000409790ENST00000396559CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
Frame-shiftENST00000409790ENST00000396559CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
Frame-shiftENST00000409790ENST00000396560CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
In-frameENST00000409552ENST00000396560CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
In-frameENST00000409552ENST00000396560CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
In-frameENST00000409790ENST00000396560CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
In-frameENST00000409790ENST00000396560CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
intron-3CDSENST00000381822ENST00000396559CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
intron-3CDSENST00000381822ENST00000396559CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
intron-3CDSENST00000381822ENST00000396560CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
intron-3CDSENST00000381822ENST00000396560CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
intron-3CDSENST00000465491ENST00000396559CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
intron-3CDSENST00000465491ENST00000396560CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
intron-5UTRENST00000465491ENST00000324570CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
intron-5UTRENST00000465491ENST00000356427CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
intron-5UTRENST00000465491ENST00000543967CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+
intron-intronENST00000381822ENST00000324570CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
intron-intronENST00000381822ENST00000324570CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
intron-intronENST00000381822ENST00000356427CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
intron-intronENST00000381822ENST00000356427CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
intron-intronENST00000381822ENST00000543967CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
intron-intronENST00000381822ENST00000543967CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
intron-intronENST00000381822ENST00000561932CLEC16Achr16

11154879

+ATF7IP2chr16

10574736

+
intron-intronENST00000381822ENST00000561932CLEC16Achr16

11154879

+ATF7IP2chr16

10574735

+
intron-intronENST00000465491ENST00000561932CLEC16Achr16

11220003

+ATF7IP2chr16

10565966

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000409790CLEC16Achr1611154879+ENST00000396560ATF7IP2chr1610574736+423523462302845871
ENST00000409552CLEC16Achr1611154879+ENST00000396560ATF7IP2chr1610574736+408821991372698853
ENST00000409790CLEC16Achr1611154879+ENST00000396560ATF7IP2chr1610574735+423523462302845871
ENST00000409552CLEC16Achr1611154879+ENST00000396560ATF7IP2chr1610574735+408821991372698853

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000409790ENST00000396560CLEC16Achr1611154879+ATF7IP2chr1610574736+0.0009534950.9990465
ENST00000409552ENST00000396560CLEC16Achr1611154879+ATF7IP2chr1610574736+0.0010051340.9989949
ENST00000409790ENST00000396560CLEC16Achr1611154879+ATF7IP2chr1610574735+0.0009534950.9990465
ENST00000409552ENST00000396560CLEC16Achr1611154879+ATF7IP2chr1610574735+0.0010051340.9989949

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Fusion Genomic Features for CLEC16A-ATF7IP2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CLEC16Achr1611220003+ATF7IP2chr1610565966+0.0020589690.99794096
CLEC16Achr1611154879+ATF7IP2chr1610574735+0.0001462410.99985373
CLEC16Achr1611154879+ATF7IP2chr1610574735+0.0001462410.99985373
CLEC16Achr1611220003+ATF7IP2chr1610565966+0.0020589690.99794096
CLEC16Achr1611154879+ATF7IP2chr1610574735+0.0001462410.99985373
CLEC16Achr1611154879+ATF7IP2chr1610574735+0.0001462410.99985373

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CLEC16A-ATF7IP2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:11154879/chr16:10574736)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCLEC16Achr16:11154879chr16:10574735ENST00000409552+182151_198687907.0DomainFPL
HgeneCLEC16Achr16:11154879chr16:10574735ENST00000409790+192451_1987051054.0DomainFPL
HgeneCLEC16Achr16:11154879chr16:10574736ENST00000409552+182151_198687907.0DomainFPL
HgeneCLEC16Achr16:11154879chr16:10574736ENST00000409790+192451_1987051054.0DomainFPL
TgeneATF7IP2chr16:11154879chr16:10574735ENST0000032457069575_680494544.0DomainFibronectin type-III
TgeneATF7IP2chr16:11154879chr16:10574735ENST00000356427710575_680516683.0DomainFibronectin type-III
TgeneATF7IP2chr16:11154879chr16:10574735ENST00000396559912575_680494544.0DomainFibronectin type-III
TgeneATF7IP2chr16:11154879chr16:10574735ENST00000396560912575_680516683.0DomainFibronectin type-III
TgeneATF7IP2chr16:11154879chr16:10574736ENST0000032457069575_680494544.0DomainFibronectin type-III
TgeneATF7IP2chr16:11154879chr16:10574736ENST00000356427710575_680516683.0DomainFibronectin type-III
TgeneATF7IP2chr16:11154879chr16:10574736ENST00000396559912575_680494544.0DomainFibronectin type-III
TgeneATF7IP2chr16:11154879chr16:10574736ENST00000396560912575_680516683.0DomainFibronectin type-III

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCLEC16Achr16:11154879chr16:10574735ENST00000381822+14892_9330141.0Compositional biasNote=Ser-rich
HgeneCLEC16Achr16:11154879chr16:10574735ENST00000409552+1821892_933687907.0Compositional biasNote=Ser-rich
HgeneCLEC16Achr16:11154879chr16:10574735ENST00000409790+1924892_9337051054.0Compositional biasNote=Ser-rich
HgeneCLEC16Achr16:11154879chr16:10574736ENST00000381822+14892_9330141.0Compositional biasNote=Ser-rich
HgeneCLEC16Achr16:11154879chr16:10574736ENST00000409552+1821892_933687907.0Compositional biasNote=Ser-rich
HgeneCLEC16Achr16:11154879chr16:10574736ENST00000409790+1924892_9337051054.0Compositional biasNote=Ser-rich
HgeneCLEC16Achr16:11154879chr16:10574735ENST00000381822+1451_1980141.0DomainFPL
HgeneCLEC16Achr16:11154879chr16:10574736ENST00000381822+1451_1980141.0DomainFPL
TgeneATF7IP2chr16:11154879chr16:10574735ENST0000032457069328_378494544.0Coiled coilOntology_term=ECO:0000255
TgeneATF7IP2chr16:11154879chr16:10574735ENST00000356427710328_378516683.0Coiled coilOntology_term=ECO:0000255
TgeneATF7IP2chr16:11154879chr16:10574735ENST00000396559912328_378494544.0Coiled coilOntology_term=ECO:0000255
TgeneATF7IP2chr16:11154879chr16:10574735ENST00000396560912328_378516683.0Coiled coilOntology_term=ECO:0000255
TgeneATF7IP2chr16:11154879chr16:10574736ENST0000032457069328_378494544.0Coiled coilOntology_term=ECO:0000255
TgeneATF7IP2chr16:11154879chr16:10574736ENST00000356427710328_378516683.0Coiled coilOntology_term=ECO:0000255
TgeneATF7IP2chr16:11154879chr16:10574736ENST00000396559912328_378494544.0Coiled coilOntology_term=ECO:0000255
TgeneATF7IP2chr16:11154879chr16:10574736ENST00000396560912328_378516683.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for CLEC16A-ATF7IP2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>17074_17074_1_CLEC16A-ATF7IP2_CLEC16A_chr16_11154879_ENST00000409552_ATF7IP2_chr16_10574735_ENST00000396560_length(transcript)=4088nt_BP=2199nt
CGGGGAGGAAGGCGGCTCGCGGTTCCTCCACCGCCTCCGCCGCCGCATCCTCCGCTTGTGCTACCGCCGCGGGCGCTGGGCCGCTCTGCT
GGTCCGGCATGAGACCGTGAGACGAGAGACGGGTCGGGGCCGCCGACATGTTTGGCCGCTCGCGGAGCTGGGTGGGCGGGGGCCATGGCA
AGACTTCCCGCAACATCCACTCCTTGGACCACCTCAAGTATCTGTACCACGTTTTGACCAAAAACACCACAGTCACAGAACAGAACCGGA
ACCTGCTAGTGGAGACCATCCGTTCCATCACTGAGATCCTGATCTGGGGAGATCAAAATGACAGCTCTGTATTTGACTTCTTCCTGGAGA
AGAATATGTTTGTTTTCTTCTTGAACATCTTGCGGCAAAAGTCGGGCCGTTACGTGTGCGTTCAGCTGCTGCAGACCTTGAACATCCTCT
TTGAGAACATCAGTCACGAGACCTCACTTTATTATTTGCTCTCAAATAACTACGTAAATTCTATCATCGTTCATAAATTTGACTTTTCTG
ATGAGGAGATTATGGCCTATTATATATCGTTCCTGAAAACACTTTCGTTAAAACTCAACAACCACACTGTCCATTTCTTTTATAATGAGC
ACACCAATGACTTTGCCCTGTACACAGAAGCCATCAAGTTTTTCAACCACCCTGAAAGCATGGTTAGAATTGCTGTAAGAACCATAACTT
TGAATGTCTATAAAGTGGATAACCAGGCCATGCTGCACTACATCCGAGATAAAACTGCTGTTCCTTACTTCTCCAATTTGGTCTGGTTCA
TTGGGAGCCATGTGATCGAACTCGATGACTGCGTGCAGACTGATGAGGAGCATCGGAATCGGGGTAAACTGAGTGATCTGGTGGCAGAGC
ACCTAGACCACCTGCACTATCTCAATGACATCCTGATCATCAACTGTGAGTTCCTCAACGATGTGCTCACTGACCACCTGCTCAACAGGC
TCTTCCTGCCCCTCTACGTGTACTCACTGGAGAACCAGGACAAGGGAGGAGAACGGCCGAAAATTAGCCTGCCGGTGTCTCTTTATCTTC
TGTCACAGGTCTTCTTAATTATACATCATGCACCGCTGGTGAACTCGTTAGCTGAAGTCATTCTGAATGGTGATCTGTCTGAGATGTACG
CTAAGACTGAACAGGATATTCAGAGAAGTTCTGCCAAGCCCAGCATTCGGTGCTTCATTAAACCCACCGAGACACTCGAGCGGTCCCTTG
AGATGAACAAGCACAAGGGCAAGAGGCGGGTGCAAAAGAGACCCAACTACAAAAACGTTGGGGAAGAAGAAGATGAGGAGAAAGGGCCCA
CCGAGGATGCCCAAGAAGACGCCGAGAAGGCTAAAGAGATCGAGATGGTGATCATGGAGCGTAGCAAGCTCTCAGAGCTGGCCGCCAGCA
CCTCCGTGCAGGAGCAGAACACCACGGACGAGGAGAAAAGCGCCGCCGCCACCTGCTCTGAGAGCACGCAATGGAGCAGACCCTTCCTGG
ATATGGTGTACCACGCGCTGGACAGCCCGGATGATGATTACCATGCCCTGTTCGTGCTCTGCCTCCTCTATGCCATGTCTCATAATAAAG
GCATGGATCCTGAAAAATTAGAGCGAATCCAGCTCCCCGTGCCAAATGCGGCCGAGAAGACCACCTACAACCACCCGCTAGCTGAAAGAC
TCATCAGGATCATGAACAACGCTGCCCAGCCAGATGGGAAGATCCGGCTGGCGACGCTGGAGCTGAGCTGCCTGCTTCTGAAGCAGCAAG
TCCTGATGAGTGCTGGCTGCATCATGAAGGACGTGCACCTGGCCTGCCTGGAGGGTGCGAGAGAAGAAAGTGTTCACCTTGTACGACATT
TTTATAAGGGAGAAGACATTTTTTTGGACATGTTTGAAGATGAGTATAGGAGCATGACAATGAAGCCCATGAACGTGGAATATCTCATGA
TGGACGCCTCCATCCTGCTGCCCCCAACAGGCACGCCACTGACGGGCATTGACTTCGTGAAGCGGCTGCCGTGTGGCGATGTGGAGAAGA
CCCGGCGGGCCATCCGGGTGTTCTTCATGCTGCGTTCCCTGTCACTGCAATTGCGAGGGGAGCCTGAGACACAGTTGCCGCTGACTCGGG
AGGAGGACCTGATCAAGACTGATGATGTCCTGGATCTGAAAAGTCCAGTATCCCCCCTGGAGTCACATTCGAAAGCTGCTTCAAACTCAA
AGGAAACAACCCCATTGGCACAAAATGCAGTCCAGGTTCCTGAGTCCTTTGAGCACCTGCCACCTCTCCCAGAACCACCAGCACCACTAC
CTGAATTAGTAGACAAAACCCGAGACACACTTCCTCCCCAGAAGCCTGAGCTCAAAGTGAAACGGGTTTTCAGACCCAATGGCATTGCCC
TGACTTGGAATATAACCAAAATCAATCCCAAGTGTGCTCCTGTAGAAAGCTACCACCTCTTCCTGTGTCATGAGAACTCTAATAATAAGT
TGATTTGGAAGAAGATTGGAGAAATTAAAGCTTTACCACTCCCCATGGCCTGTACTTTATCTCAGTTTTTAGCTTCCAACAGATACTATT
TTACTGTCCAATCAAAAGATATTTTTGGACGATATGGACCATTCTGTGATATAAAATCTATCCCTGGGTTTTCTGAAAATCTTACGTAAA
AGGTGTTTAATAATGATATACTACTTTTTTTTTCATATTTGTTTGTTTGCAATGTTACTGTAATACTATTTGCCATTGTAAAAGGCCAGC
TCAGATTGTGAGCCCTTTCTATTGGGACAGTCCTCTTCTATATGTTTTAAGTGGCCAGTAATTTAATGAATTTCTGGTTTGTATTAAATA
TGTCCTTCCAATGGATAAGTTCTAAAACATACGCTATCATTGGCCCATGTTGCTGAGGTGCATTGTGAACAATACCTTTAGTGACTGTGG
AACTGCTGCTTCTATCAGAAGACCTAGGATACAAGCAGCCACTGTTTCCTCCGTTAACAATCAGCTTTTAGTAACCTGCTGTGGTCAGCA
TAGCTACAGGAAAAGTCAGCCCTTGACTGAGGGCCAGATCATCCCTGGAGTGCACCTCTACTAAGATTTTATGAAAAGATGACATGTTGG
GCTGCATGATAAAAGTTAATTATAAAAATTAAAAGATTTTTTTTTTTGAGATGGAATATTGCTCTGTTGCCCAGGCTGGAGTACAGTGGT
CACTGCAACCTCCATCTCCCTGGTTCAAGCAATTCTCCTATGTCAGCCTCCCAAGTAGCTGGGACTATAGTCACTTGCCACCATGCCCGG
CTAATTTATTTTTAGTAGAGATGAGGTTTCACCTTGTTGGTCAGGCTGGTCTCAAACTCCTGACCTCAGGGGATCCACCCGCCTCGGCCT
CCCGAAGTGCTGGGATTATAGGCGTAAGCCACCATGCCTGGCCAAAAATTAAAAGATTTTATGAAACGAAATGGCTTCCCATTCTTTCTA
TTCAGCTTCTAAGTGGGCTATTCATTTGTGCTCTCCTCTTTTTTGTTTTGTTTTGCACTTTGTCAATCATTTGGGGAAATAGCCTGGAGG
TCTTTCCTGAATCTGTTTGTAGACATAATAAAATTTGTGTGCTGTGTACACAAAAACATAATGTATCTTATGAAAGCATTACCCAACCTG
TTTGAGTTGAGAATGCATTTGTCCACCTTTGATTTGAGGCTTTAGTTTGCTGATTTCCTAAATGCTACCCTTTGATCATTTCCTGGCCAC
CATCACAATACTAAGGGGCTCAGATGTGTCTTGTGCCCACCTCTTCCTGAGAAGAGATGGAAGTGGAGCTGTGACTAGTACAAGCAGCCC
AAGAAACTCTGAACGGGGCCCAATGGAGGCAAACTTGAGCAAATAATTGGGATGATAAGAAACAAAAATAATCCCAACTGTTTGAAAGTT
CGAAAGAGGGGCATTCTTTTCTGGTACATGGTGAGAGTTCAGGCTCCAGAGACTCAAAACGGAATGGTTTTCCTTGGCATTTTGTAAATG
CTCTCACATCTGTAGCAATAAAGCTGTTATTTTCTGCA

>17074_17074_1_CLEC16A-ATF7IP2_CLEC16A_chr16_11154879_ENST00000409552_ATF7IP2_chr16_10574735_ENST00000396560_length(amino acids)=853AA_BP=683
MFGRSRSWVGGGHGKTSRNIHSLDHLKYLYHVLTKNTTVTEQNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSG
RYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFN
HPESMVRIAVRTITLNVYKVDNQAMLHYIRDKTAVPYFSNLVWFIGSHVIELDDCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINC
EFLNDVLTDHLLNRLFLPLYVYSLENQDKGGERPKISLPVSLYLLSQVFLIIHHAPLVNSLAEVILNGDLSEMYAKTEQDIQRSSAKPSI
RCFIKPTETLERSLEMNKHKGKRRVQKRPNYKNVGEEEDEEKGPTEDAQEDAEKAKEIEMVIMERSKLSELAASTSVQEQNTTDEEKSAA
ATCSESTQWSRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLERIQLPVPNAAEKTTYNHPLAERLIRIMNNAAQPDGKIR
LATLELSCLLLKQQVLMSAGCIMKDVHLACLEGAREESVHLVRHFYKGEDIFLDMFEDEYRSMTMKPMNVEYLMMDASILLPPTGTPLTG
IDFVKRLPCGDVEKTRRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLKSPVSPLESHSKAASNSKETTPLAQNAVQVPES
FEHLPPLPEPPAPLPELVDKTRDTLPPQKPELKVKRVFRPNGIALTWNITKINPKCAPVESYHLFLCHENSNNKLIWKKIGEIKALPLPM
ACTLSQFLASNRYYFTVQSKDIFGRYGPFCDIKSIPGFSENLT

--------------------------------------------------------------
>17074_17074_2_CLEC16A-ATF7IP2_CLEC16A_chr16_11154879_ENST00000409552_ATF7IP2_chr16_10574736_ENST00000396560_length(transcript)=4088nt_BP=2199nt
CGGGGAGGAAGGCGGCTCGCGGTTCCTCCACCGCCTCCGCCGCCGCATCCTCCGCTTGTGCTACCGCCGCGGGCGCTGGGCCGCTCTGCT
GGTCCGGCATGAGACCGTGAGACGAGAGACGGGTCGGGGCCGCCGACATGTTTGGCCGCTCGCGGAGCTGGGTGGGCGGGGGCCATGGCA
AGACTTCCCGCAACATCCACTCCTTGGACCACCTCAAGTATCTGTACCACGTTTTGACCAAAAACACCACAGTCACAGAACAGAACCGGA
ACCTGCTAGTGGAGACCATCCGTTCCATCACTGAGATCCTGATCTGGGGAGATCAAAATGACAGCTCTGTATTTGACTTCTTCCTGGAGA
AGAATATGTTTGTTTTCTTCTTGAACATCTTGCGGCAAAAGTCGGGCCGTTACGTGTGCGTTCAGCTGCTGCAGACCTTGAACATCCTCT
TTGAGAACATCAGTCACGAGACCTCACTTTATTATTTGCTCTCAAATAACTACGTAAATTCTATCATCGTTCATAAATTTGACTTTTCTG
ATGAGGAGATTATGGCCTATTATATATCGTTCCTGAAAACACTTTCGTTAAAACTCAACAACCACACTGTCCATTTCTTTTATAATGAGC
ACACCAATGACTTTGCCCTGTACACAGAAGCCATCAAGTTTTTCAACCACCCTGAAAGCATGGTTAGAATTGCTGTAAGAACCATAACTT
TGAATGTCTATAAAGTGGATAACCAGGCCATGCTGCACTACATCCGAGATAAAACTGCTGTTCCTTACTTCTCCAATTTGGTCTGGTTCA
TTGGGAGCCATGTGATCGAACTCGATGACTGCGTGCAGACTGATGAGGAGCATCGGAATCGGGGTAAACTGAGTGATCTGGTGGCAGAGC
ACCTAGACCACCTGCACTATCTCAATGACATCCTGATCATCAACTGTGAGTTCCTCAACGATGTGCTCACTGACCACCTGCTCAACAGGC
TCTTCCTGCCCCTCTACGTGTACTCACTGGAGAACCAGGACAAGGGAGGAGAACGGCCGAAAATTAGCCTGCCGGTGTCTCTTTATCTTC
TGTCACAGGTCTTCTTAATTATACATCATGCACCGCTGGTGAACTCGTTAGCTGAAGTCATTCTGAATGGTGATCTGTCTGAGATGTACG
CTAAGACTGAACAGGATATTCAGAGAAGTTCTGCCAAGCCCAGCATTCGGTGCTTCATTAAACCCACCGAGACACTCGAGCGGTCCCTTG
AGATGAACAAGCACAAGGGCAAGAGGCGGGTGCAAAAGAGACCCAACTACAAAAACGTTGGGGAAGAAGAAGATGAGGAGAAAGGGCCCA
CCGAGGATGCCCAAGAAGACGCCGAGAAGGCTAAAGAGATCGAGATGGTGATCATGGAGCGTAGCAAGCTCTCAGAGCTGGCCGCCAGCA
CCTCCGTGCAGGAGCAGAACACCACGGACGAGGAGAAAAGCGCCGCCGCCACCTGCTCTGAGAGCACGCAATGGAGCAGACCCTTCCTGG
ATATGGTGTACCACGCGCTGGACAGCCCGGATGATGATTACCATGCCCTGTTCGTGCTCTGCCTCCTCTATGCCATGTCTCATAATAAAG
GCATGGATCCTGAAAAATTAGAGCGAATCCAGCTCCCCGTGCCAAATGCGGCCGAGAAGACCACCTACAACCACCCGCTAGCTGAAAGAC
TCATCAGGATCATGAACAACGCTGCCCAGCCAGATGGGAAGATCCGGCTGGCGACGCTGGAGCTGAGCTGCCTGCTTCTGAAGCAGCAAG
TCCTGATGAGTGCTGGCTGCATCATGAAGGACGTGCACCTGGCCTGCCTGGAGGGTGCGAGAGAAGAAAGTGTTCACCTTGTACGACATT
TTTATAAGGGAGAAGACATTTTTTTGGACATGTTTGAAGATGAGTATAGGAGCATGACAATGAAGCCCATGAACGTGGAATATCTCATGA
TGGACGCCTCCATCCTGCTGCCCCCAACAGGCACGCCACTGACGGGCATTGACTTCGTGAAGCGGCTGCCGTGTGGCGATGTGGAGAAGA
CCCGGCGGGCCATCCGGGTGTTCTTCATGCTGCGTTCCCTGTCACTGCAATTGCGAGGGGAGCCTGAGACACAGTTGCCGCTGACTCGGG
AGGAGGACCTGATCAAGACTGATGATGTCCTGGATCTGAAAAGTCCAGTATCCCCCCTGGAGTCACATTCGAAAGCTGCTTCAAACTCAA
AGGAAACAACCCCATTGGCACAAAATGCAGTCCAGGTTCCTGAGTCCTTTGAGCACCTGCCACCTCTCCCAGAACCACCAGCACCACTAC
CTGAATTAGTAGACAAAACCCGAGACACACTTCCTCCCCAGAAGCCTGAGCTCAAAGTGAAACGGGTTTTCAGACCCAATGGCATTGCCC
TGACTTGGAATATAACCAAAATCAATCCCAAGTGTGCTCCTGTAGAAAGCTACCACCTCTTCCTGTGTCATGAGAACTCTAATAATAAGT
TGATTTGGAAGAAGATTGGAGAAATTAAAGCTTTACCACTCCCCATGGCCTGTACTTTATCTCAGTTTTTAGCTTCCAACAGATACTATT
TTACTGTCCAATCAAAAGATATTTTTGGACGATATGGACCATTCTGTGATATAAAATCTATCCCTGGGTTTTCTGAAAATCTTACGTAAA
AGGTGTTTAATAATGATATACTACTTTTTTTTTCATATTTGTTTGTTTGCAATGTTACTGTAATACTATTTGCCATTGTAAAAGGCCAGC
TCAGATTGTGAGCCCTTTCTATTGGGACAGTCCTCTTCTATATGTTTTAAGTGGCCAGTAATTTAATGAATTTCTGGTTTGTATTAAATA
TGTCCTTCCAATGGATAAGTTCTAAAACATACGCTATCATTGGCCCATGTTGCTGAGGTGCATTGTGAACAATACCTTTAGTGACTGTGG
AACTGCTGCTTCTATCAGAAGACCTAGGATACAAGCAGCCACTGTTTCCTCCGTTAACAATCAGCTTTTAGTAACCTGCTGTGGTCAGCA
TAGCTACAGGAAAAGTCAGCCCTTGACTGAGGGCCAGATCATCCCTGGAGTGCACCTCTACTAAGATTTTATGAAAAGATGACATGTTGG
GCTGCATGATAAAAGTTAATTATAAAAATTAAAAGATTTTTTTTTTTGAGATGGAATATTGCTCTGTTGCCCAGGCTGGAGTACAGTGGT
CACTGCAACCTCCATCTCCCTGGTTCAAGCAATTCTCCTATGTCAGCCTCCCAAGTAGCTGGGACTATAGTCACTTGCCACCATGCCCGG
CTAATTTATTTTTAGTAGAGATGAGGTTTCACCTTGTTGGTCAGGCTGGTCTCAAACTCCTGACCTCAGGGGATCCACCCGCCTCGGCCT
CCCGAAGTGCTGGGATTATAGGCGTAAGCCACCATGCCTGGCCAAAAATTAAAAGATTTTATGAAACGAAATGGCTTCCCATTCTTTCTA
TTCAGCTTCTAAGTGGGCTATTCATTTGTGCTCTCCTCTTTTTTGTTTTGTTTTGCACTTTGTCAATCATTTGGGGAAATAGCCTGGAGG
TCTTTCCTGAATCTGTTTGTAGACATAATAAAATTTGTGTGCTGTGTACACAAAAACATAATGTATCTTATGAAAGCATTACCCAACCTG
TTTGAGTTGAGAATGCATTTGTCCACCTTTGATTTGAGGCTTTAGTTTGCTGATTTCCTAAATGCTACCCTTTGATCATTTCCTGGCCAC
CATCACAATACTAAGGGGCTCAGATGTGTCTTGTGCCCACCTCTTCCTGAGAAGAGATGGAAGTGGAGCTGTGACTAGTACAAGCAGCCC
AAGAAACTCTGAACGGGGCCCAATGGAGGCAAACTTGAGCAAATAATTGGGATGATAAGAAACAAAAATAATCCCAACTGTTTGAAAGTT
CGAAAGAGGGGCATTCTTTTCTGGTACATGGTGAGAGTTCAGGCTCCAGAGACTCAAAACGGAATGGTTTTCCTTGGCATTTTGTAAATG
CTCTCACATCTGTAGCAATAAAGCTGTTATTTTCTGCA

>17074_17074_2_CLEC16A-ATF7IP2_CLEC16A_chr16_11154879_ENST00000409552_ATF7IP2_chr16_10574736_ENST00000396560_length(amino acids)=853AA_BP=683
MFGRSRSWVGGGHGKTSRNIHSLDHLKYLYHVLTKNTTVTEQNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSG
RYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFN
HPESMVRIAVRTITLNVYKVDNQAMLHYIRDKTAVPYFSNLVWFIGSHVIELDDCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINC
EFLNDVLTDHLLNRLFLPLYVYSLENQDKGGERPKISLPVSLYLLSQVFLIIHHAPLVNSLAEVILNGDLSEMYAKTEQDIQRSSAKPSI
RCFIKPTETLERSLEMNKHKGKRRVQKRPNYKNVGEEEDEEKGPTEDAQEDAEKAKEIEMVIMERSKLSELAASTSVQEQNTTDEEKSAA
ATCSESTQWSRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLERIQLPVPNAAEKTTYNHPLAERLIRIMNNAAQPDGKIR
LATLELSCLLLKQQVLMSAGCIMKDVHLACLEGAREESVHLVRHFYKGEDIFLDMFEDEYRSMTMKPMNVEYLMMDASILLPPTGTPLTG
IDFVKRLPCGDVEKTRRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLKSPVSPLESHSKAASNSKETTPLAQNAVQVPES
FEHLPPLPEPPAPLPELVDKTRDTLPPQKPELKVKRVFRPNGIALTWNITKINPKCAPVESYHLFLCHENSNNKLIWKKIGEIKALPLPM
ACTLSQFLASNRYYFTVQSKDIFGRYGPFCDIKSIPGFSENLT

--------------------------------------------------------------
>17074_17074_3_CLEC16A-ATF7IP2_CLEC16A_chr16_11154879_ENST00000409790_ATF7IP2_chr16_10574735_ENST00000396560_length(transcript)=4235nt_BP=2346nt
AACTGCATTTCCCAGCGCCCCACGCGGCGGCGGCCGTAAAGCGCGGCGGTCGAACGGCCGGTTCCGGCTGAATGTCAGTGCTGGGCTGTG
GGCCGGGGAGGAAGGCGGCTCGCGGTTCCTCCACCGCCTCCGCCGCCGCATCCTCCGCTTGTGCTACCGCCGCGGGCGCTGGGCCGCTCT
GCTGGTCCGGCATGAGACCGTGAGACGAGAGACGGGTCGGGGCCGCCGACATGTTTGGCCGCTCGCGGAGCTGGGTGGGCGGGGGCCATG
GCAAGACTTCCCGCAACATCCACTCCTTGGACCACCTCAAGTATCTGTACCACGTTTTGACCAAAAACACCACAGTCACAGAACAGAACC
GGAACCTGCTAGTGGAGACCATCCGTTCCATCACTGAGATCCTGATCTGGGGAGATCAAAATGACAGCTCTGTATTTGACTTCTTCCTGG
AGAAGAATATGTTTGTTTTCTTCTTGAACATCTTGCGGCAAAAGTCGGGCCGTTACGTGTGCGTTCAGCTGCTGCAGACCTTGAACATCC
TCTTTGAGAACATCAGTCACGAGACCTCACTTTATTATTTGCTCTCAAATAACTACGTAAATTCTATCATCGTTCATAAATTTGACTTTT
CTGATGAGGAGATTATGGCCTATTATATATCGTTCCTGAAAACACTTTCGTTAAAACTCAACAACCACACTGTCCATTTCTTTTATAATG
AGCACACCAATGACTTTGCCCTGTACACAGAAGCCATCAAGTTTTTCAACCACCCTGAAAGCATGGTTAGAATTGCTGTAAGAACCATAA
CTTTGAATGTCTATAAAGTGTCATTGGATAACCAGGCCATGCTGCACTACATCCGAGATAAAACTGCTGTTCCTTACTTCTCCAATTTGG
TCTGGTTCATTGGGAGCCATGTGATCGAACTCGATGACTGCGTGCAGACTGATGAGGAGCATCGGAATCGGGGTAAACTGAGTGATCTGG
TGGCAGAGCACCTAGACCACCTGCACTATCTCAATGACATCCTGATCATCAACTGTGAGTTCCTCAACGATGTGCTCACTGACCACCTGC
TCAACAGGCTCTTCCTGCCCCTCTACGTGTACTCACTGGAGAACCAGGACAAGGGAGGAGAACGGCCGAAAATTAGCCTGCCGGTGTCTC
TTTATCTTCTGTCACAGGTCTTCTTAATTATACATCATGCACCGCTGGTGAACTCGTTAGCTGAAGTCATTCTGAATGGTGATCTGTCTG
AGATGTACGCTAAGACTGAACAGGATATTCAGAGAAGTTCTGCCAAGCCCAGCATTCGGTGCTTCATTAAACCCACCGAGACACTCGAGC
GGTCCCTTGAGATGAACAAGCACAAGGGCAAGAGGCGGGTGCAAAAGAGACCCAACTACAAAAACGTTGGGGAAGAAGAAGATGAGGAGA
AAGGGCCCACCGAGGATGCCCAAGAAGACGCCGAGAAGGCTAAAGGTACAGAGGGTGGTTCAAAAGGCATCAAGACGAGTGGGGAGAGTG
AAGAGATCGAGATGGTGATCATGGAGCGTAGCAAGCTCTCAGAGCTGGCCGCCAGCACCTCCGTGCAGGAGCAGAACACCACGGACGAGG
AGAAAAGCGCCGCCGCCACCTGCTCTGAGAGCACGCAATGGAGCAGACCCTTCCTGGATATGGTGTACCACGCGCTGGACAGCCCGGATG
ATGATTACCATGCCCTGTTCGTGCTCTGCCTCCTCTATGCCATGTCTCATAATAAAGGCATGGATCCTGAAAAATTAGAGCGAATCCAGC
TCCCCGTGCCAAATGCGGCCGAGAAGACCACCTACAACCACCCGCTAGCTGAAAGACTCATCAGGATCATGAACAACGCTGCCCAGCCAG
ATGGGAAGATCCGGCTGGCGACGCTGGAGCTGAGCTGCCTGCTTCTGAAGCAGCAAGTCCTGATGAGTGCTGGCTGCATCATGAAGGACG
TGCACCTGGCCTGCCTGGAGGGTGCGAGAGAAGAAAGTGTTCACCTTGTACGACATTTTTATAAGGGAGAAGACATTTTTTTGGACATGT
TTGAAGATGAGTATAGGAGCATGACAATGAAGCCCATGAACGTGGAATATCTCATGATGGACGCCTCCATCCTGCTGCCCCCAACAGGCA
CGCCACTGACGGGCATTGACTTCGTGAAGCGGCTGCCGTGTGGCGATGTGGAGAAGACCCGGCGGGCCATCCGGGTGTTCTTCATGCTGC
GTTCCCTGTCACTGCAATTGCGAGGGGAGCCTGAGACACAGTTGCCGCTGACTCGGGAGGAGGACCTGATCAAGACTGATGATGTCCTGG
ATCTGAAAAGTCCAGTATCCCCCCTGGAGTCACATTCGAAAGCTGCTTCAAACTCAAAGGAAACAACCCCATTGGCACAAAATGCAGTCC
AGGTTCCTGAGTCCTTTGAGCACCTGCCACCTCTCCCAGAACCACCAGCACCACTACCTGAATTAGTAGACAAAACCCGAGACACACTTC
CTCCCCAGAAGCCTGAGCTCAAAGTGAAACGGGTTTTCAGACCCAATGGCATTGCCCTGACTTGGAATATAACCAAAATCAATCCCAAGT
GTGCTCCTGTAGAAAGCTACCACCTCTTCCTGTGTCATGAGAACTCTAATAATAAGTTGATTTGGAAGAAGATTGGAGAAATTAAAGCTT
TACCACTCCCCATGGCCTGTACTTTATCTCAGTTTTTAGCTTCCAACAGATACTATTTTACTGTCCAATCAAAAGATATTTTTGGACGAT
ATGGACCATTCTGTGATATAAAATCTATCCCTGGGTTTTCTGAAAATCTTACGTAAAAGGTGTTTAATAATGATATACTACTTTTTTTTT
CATATTTGTTTGTTTGCAATGTTACTGTAATACTATTTGCCATTGTAAAAGGCCAGCTCAGATTGTGAGCCCTTTCTATTGGGACAGTCC
TCTTCTATATGTTTTAAGTGGCCAGTAATTTAATGAATTTCTGGTTTGTATTAAATATGTCCTTCCAATGGATAAGTTCTAAAACATACG
CTATCATTGGCCCATGTTGCTGAGGTGCATTGTGAACAATACCTTTAGTGACTGTGGAACTGCTGCTTCTATCAGAAGACCTAGGATACA
AGCAGCCACTGTTTCCTCCGTTAACAATCAGCTTTTAGTAACCTGCTGTGGTCAGCATAGCTACAGGAAAAGTCAGCCCTTGACTGAGGG
CCAGATCATCCCTGGAGTGCACCTCTACTAAGATTTTATGAAAAGATGACATGTTGGGCTGCATGATAAAAGTTAATTATAAAAATTAAA
AGATTTTTTTTTTTGAGATGGAATATTGCTCTGTTGCCCAGGCTGGAGTACAGTGGTCACTGCAACCTCCATCTCCCTGGTTCAAGCAAT
TCTCCTATGTCAGCCTCCCAAGTAGCTGGGACTATAGTCACTTGCCACCATGCCCGGCTAATTTATTTTTAGTAGAGATGAGGTTTCACC
TTGTTGGTCAGGCTGGTCTCAAACTCCTGACCTCAGGGGATCCACCCGCCTCGGCCTCCCGAAGTGCTGGGATTATAGGCGTAAGCCACC
ATGCCTGGCCAAAAATTAAAAGATTTTATGAAACGAAATGGCTTCCCATTCTTTCTATTCAGCTTCTAAGTGGGCTATTCATTTGTGCTC
TCCTCTTTTTTGTTTTGTTTTGCACTTTGTCAATCATTTGGGGAAATAGCCTGGAGGTCTTTCCTGAATCTGTTTGTAGACATAATAAAA
TTTGTGTGCTGTGTACACAAAAACATAATGTATCTTATGAAAGCATTACCCAACCTGTTTGAGTTGAGAATGCATTTGTCCACCTTTGAT
TTGAGGCTTTAGTTTGCTGATTTCCTAAATGCTACCCTTTGATCATTTCCTGGCCACCATCACAATACTAAGGGGCTCAGATGTGTCTTG
TGCCCACCTCTTCCTGAGAAGAGATGGAAGTGGAGCTGTGACTAGTACAAGCAGCCCAAGAAACTCTGAACGGGGCCCAATGGAGGCAAA
CTTGAGCAAATAATTGGGATGATAAGAAACAAAAATAATCCCAACTGTTTGAAAGTTCGAAAGAGGGGCATTCTTTTCTGGTACATGGTG
AGAGTTCAGGCTCCAGAGACTCAAAACGGAATGGTTTTCCTTGGCATTTTGTAAATGCTCTCACATCTGTAGCAATAAAGCTGTTATTTT
CTGCA

>17074_17074_3_CLEC16A-ATF7IP2_CLEC16A_chr16_11154879_ENST00000409790_ATF7IP2_chr16_10574735_ENST00000396560_length(amino acids)=871AA_BP=701
MFGRSRSWVGGGHGKTSRNIHSLDHLKYLYHVLTKNTTVTEQNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSG
RYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFN
HPESMVRIAVRTITLNVYKVSLDNQAMLHYIRDKTAVPYFSNLVWFIGSHVIELDDCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILII
NCEFLNDVLTDHLLNRLFLPLYVYSLENQDKGGERPKISLPVSLYLLSQVFLIIHHAPLVNSLAEVILNGDLSEMYAKTEQDIQRSSAKP
SIRCFIKPTETLERSLEMNKHKGKRRVQKRPNYKNVGEEEDEEKGPTEDAQEDAEKAKGTEGGSKGIKTSGESEEIEMVIMERSKLSELA
ASTSVQEQNTTDEEKSAAATCSESTQWSRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLERIQLPVPNAAEKTTYNHPLA
ERLIRIMNNAAQPDGKIRLATLELSCLLLKQQVLMSAGCIMKDVHLACLEGAREESVHLVRHFYKGEDIFLDMFEDEYRSMTMKPMNVEY
LMMDASILLPPTGTPLTGIDFVKRLPCGDVEKTRRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLKSPVSPLESHSKAAS
NSKETTPLAQNAVQVPESFEHLPPLPEPPAPLPELVDKTRDTLPPQKPELKVKRVFRPNGIALTWNITKINPKCAPVESYHLFLCHENSN
NKLIWKKIGEIKALPLPMACTLSQFLASNRYYFTVQSKDIFGRYGPFCDIKSIPGFSENLT

--------------------------------------------------------------
>17074_17074_4_CLEC16A-ATF7IP2_CLEC16A_chr16_11154879_ENST00000409790_ATF7IP2_chr16_10574736_ENST00000396560_length(transcript)=4235nt_BP=2346nt
AACTGCATTTCCCAGCGCCCCACGCGGCGGCGGCCGTAAAGCGCGGCGGTCGAACGGCCGGTTCCGGCTGAATGTCAGTGCTGGGCTGTG
GGCCGGGGAGGAAGGCGGCTCGCGGTTCCTCCACCGCCTCCGCCGCCGCATCCTCCGCTTGTGCTACCGCCGCGGGCGCTGGGCCGCTCT
GCTGGTCCGGCATGAGACCGTGAGACGAGAGACGGGTCGGGGCCGCCGACATGTTTGGCCGCTCGCGGAGCTGGGTGGGCGGGGGCCATG
GCAAGACTTCCCGCAACATCCACTCCTTGGACCACCTCAAGTATCTGTACCACGTTTTGACCAAAAACACCACAGTCACAGAACAGAACC
GGAACCTGCTAGTGGAGACCATCCGTTCCATCACTGAGATCCTGATCTGGGGAGATCAAAATGACAGCTCTGTATTTGACTTCTTCCTGG
AGAAGAATATGTTTGTTTTCTTCTTGAACATCTTGCGGCAAAAGTCGGGCCGTTACGTGTGCGTTCAGCTGCTGCAGACCTTGAACATCC
TCTTTGAGAACATCAGTCACGAGACCTCACTTTATTATTTGCTCTCAAATAACTACGTAAATTCTATCATCGTTCATAAATTTGACTTTT
CTGATGAGGAGATTATGGCCTATTATATATCGTTCCTGAAAACACTTTCGTTAAAACTCAACAACCACACTGTCCATTTCTTTTATAATG
AGCACACCAATGACTTTGCCCTGTACACAGAAGCCATCAAGTTTTTCAACCACCCTGAAAGCATGGTTAGAATTGCTGTAAGAACCATAA
CTTTGAATGTCTATAAAGTGTCATTGGATAACCAGGCCATGCTGCACTACATCCGAGATAAAACTGCTGTTCCTTACTTCTCCAATTTGG
TCTGGTTCATTGGGAGCCATGTGATCGAACTCGATGACTGCGTGCAGACTGATGAGGAGCATCGGAATCGGGGTAAACTGAGTGATCTGG
TGGCAGAGCACCTAGACCACCTGCACTATCTCAATGACATCCTGATCATCAACTGTGAGTTCCTCAACGATGTGCTCACTGACCACCTGC
TCAACAGGCTCTTCCTGCCCCTCTACGTGTACTCACTGGAGAACCAGGACAAGGGAGGAGAACGGCCGAAAATTAGCCTGCCGGTGTCTC
TTTATCTTCTGTCACAGGTCTTCTTAATTATACATCATGCACCGCTGGTGAACTCGTTAGCTGAAGTCATTCTGAATGGTGATCTGTCTG
AGATGTACGCTAAGACTGAACAGGATATTCAGAGAAGTTCTGCCAAGCCCAGCATTCGGTGCTTCATTAAACCCACCGAGACACTCGAGC
GGTCCCTTGAGATGAACAAGCACAAGGGCAAGAGGCGGGTGCAAAAGAGACCCAACTACAAAAACGTTGGGGAAGAAGAAGATGAGGAGA
AAGGGCCCACCGAGGATGCCCAAGAAGACGCCGAGAAGGCTAAAGGTACAGAGGGTGGTTCAAAAGGCATCAAGACGAGTGGGGAGAGTG
AAGAGATCGAGATGGTGATCATGGAGCGTAGCAAGCTCTCAGAGCTGGCCGCCAGCACCTCCGTGCAGGAGCAGAACACCACGGACGAGG
AGAAAAGCGCCGCCGCCACCTGCTCTGAGAGCACGCAATGGAGCAGACCCTTCCTGGATATGGTGTACCACGCGCTGGACAGCCCGGATG
ATGATTACCATGCCCTGTTCGTGCTCTGCCTCCTCTATGCCATGTCTCATAATAAAGGCATGGATCCTGAAAAATTAGAGCGAATCCAGC
TCCCCGTGCCAAATGCGGCCGAGAAGACCACCTACAACCACCCGCTAGCTGAAAGACTCATCAGGATCATGAACAACGCTGCCCAGCCAG
ATGGGAAGATCCGGCTGGCGACGCTGGAGCTGAGCTGCCTGCTTCTGAAGCAGCAAGTCCTGATGAGTGCTGGCTGCATCATGAAGGACG
TGCACCTGGCCTGCCTGGAGGGTGCGAGAGAAGAAAGTGTTCACCTTGTACGACATTTTTATAAGGGAGAAGACATTTTTTTGGACATGT
TTGAAGATGAGTATAGGAGCATGACAATGAAGCCCATGAACGTGGAATATCTCATGATGGACGCCTCCATCCTGCTGCCCCCAACAGGCA
CGCCACTGACGGGCATTGACTTCGTGAAGCGGCTGCCGTGTGGCGATGTGGAGAAGACCCGGCGGGCCATCCGGGTGTTCTTCATGCTGC
GTTCCCTGTCACTGCAATTGCGAGGGGAGCCTGAGACACAGTTGCCGCTGACTCGGGAGGAGGACCTGATCAAGACTGATGATGTCCTGG
ATCTGAAAAGTCCAGTATCCCCCCTGGAGTCACATTCGAAAGCTGCTTCAAACTCAAAGGAAACAACCCCATTGGCACAAAATGCAGTCC
AGGTTCCTGAGTCCTTTGAGCACCTGCCACCTCTCCCAGAACCACCAGCACCACTACCTGAATTAGTAGACAAAACCCGAGACACACTTC
CTCCCCAGAAGCCTGAGCTCAAAGTGAAACGGGTTTTCAGACCCAATGGCATTGCCCTGACTTGGAATATAACCAAAATCAATCCCAAGT
GTGCTCCTGTAGAAAGCTACCACCTCTTCCTGTGTCATGAGAACTCTAATAATAAGTTGATTTGGAAGAAGATTGGAGAAATTAAAGCTT
TACCACTCCCCATGGCCTGTACTTTATCTCAGTTTTTAGCTTCCAACAGATACTATTTTACTGTCCAATCAAAAGATATTTTTGGACGAT
ATGGACCATTCTGTGATATAAAATCTATCCCTGGGTTTTCTGAAAATCTTACGTAAAAGGTGTTTAATAATGATATACTACTTTTTTTTT
CATATTTGTTTGTTTGCAATGTTACTGTAATACTATTTGCCATTGTAAAAGGCCAGCTCAGATTGTGAGCCCTTTCTATTGGGACAGTCC
TCTTCTATATGTTTTAAGTGGCCAGTAATTTAATGAATTTCTGGTTTGTATTAAATATGTCCTTCCAATGGATAAGTTCTAAAACATACG
CTATCATTGGCCCATGTTGCTGAGGTGCATTGTGAACAATACCTTTAGTGACTGTGGAACTGCTGCTTCTATCAGAAGACCTAGGATACA
AGCAGCCACTGTTTCCTCCGTTAACAATCAGCTTTTAGTAACCTGCTGTGGTCAGCATAGCTACAGGAAAAGTCAGCCCTTGACTGAGGG
CCAGATCATCCCTGGAGTGCACCTCTACTAAGATTTTATGAAAAGATGACATGTTGGGCTGCATGATAAAAGTTAATTATAAAAATTAAA
AGATTTTTTTTTTTGAGATGGAATATTGCTCTGTTGCCCAGGCTGGAGTACAGTGGTCACTGCAACCTCCATCTCCCTGGTTCAAGCAAT
TCTCCTATGTCAGCCTCCCAAGTAGCTGGGACTATAGTCACTTGCCACCATGCCCGGCTAATTTATTTTTAGTAGAGATGAGGTTTCACC
TTGTTGGTCAGGCTGGTCTCAAACTCCTGACCTCAGGGGATCCACCCGCCTCGGCCTCCCGAAGTGCTGGGATTATAGGCGTAAGCCACC
ATGCCTGGCCAAAAATTAAAAGATTTTATGAAACGAAATGGCTTCCCATTCTTTCTATTCAGCTTCTAAGTGGGCTATTCATTTGTGCTC
TCCTCTTTTTTGTTTTGTTTTGCACTTTGTCAATCATTTGGGGAAATAGCCTGGAGGTCTTTCCTGAATCTGTTTGTAGACATAATAAAA
TTTGTGTGCTGTGTACACAAAAACATAATGTATCTTATGAAAGCATTACCCAACCTGTTTGAGTTGAGAATGCATTTGTCCACCTTTGAT
TTGAGGCTTTAGTTTGCTGATTTCCTAAATGCTACCCTTTGATCATTTCCTGGCCACCATCACAATACTAAGGGGCTCAGATGTGTCTTG
TGCCCACCTCTTCCTGAGAAGAGATGGAAGTGGAGCTGTGACTAGTACAAGCAGCCCAAGAAACTCTGAACGGGGCCCAATGGAGGCAAA
CTTGAGCAAATAATTGGGATGATAAGAAACAAAAATAATCCCAACTGTTTGAAAGTTCGAAAGAGGGGCATTCTTTTCTGGTACATGGTG
AGAGTTCAGGCTCCAGAGACTCAAAACGGAATGGTTTTCCTTGGCATTTTGTAAATGCTCTCACATCTGTAGCAATAAAGCTGTTATTTT
CTGCA

>17074_17074_4_CLEC16A-ATF7IP2_CLEC16A_chr16_11154879_ENST00000409790_ATF7IP2_chr16_10574736_ENST00000396560_length(amino acids)=871AA_BP=701
MFGRSRSWVGGGHGKTSRNIHSLDHLKYLYHVLTKNTTVTEQNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSG
RYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFN
HPESMVRIAVRTITLNVYKVSLDNQAMLHYIRDKTAVPYFSNLVWFIGSHVIELDDCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILII
NCEFLNDVLTDHLLNRLFLPLYVYSLENQDKGGERPKISLPVSLYLLSQVFLIIHHAPLVNSLAEVILNGDLSEMYAKTEQDIQRSSAKP
SIRCFIKPTETLERSLEMNKHKGKRRVQKRPNYKNVGEEEDEEKGPTEDAQEDAEKAKGTEGGSKGIKTSGESEEIEMVIMERSKLSELA
ASTSVQEQNTTDEEKSAAATCSESTQWSRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLERIQLPVPNAAEKTTYNHPLA
ERLIRIMNNAAQPDGKIRLATLELSCLLLKQQVLMSAGCIMKDVHLACLEGAREESVHLVRHFYKGEDIFLDMFEDEYRSMTMKPMNVEY
LMMDASILLPPTGTPLTGIDFVKRLPCGDVEKTRRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLKSPVSPLESHSKAAS
NSKETTPLAQNAVQVPESFEHLPPLPEPPAPLPELVDKTRDTLPPQKPELKVKRVFRPNGIALTWNITKINPKCAPVESYHLFLCHENSN
NKLIWKKIGEIKALPLPMACTLSQFLASNRYYFTVQSKDIFGRYGPFCDIKSIPGFSENLT

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Fusion Gene PPI Analysis for CLEC16A-ATF7IP2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CLEC16A-ATF7IP2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CLEC16A-ATF7IP2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCLEC16AC0011854Diabetes Mellitus, Insulin-Dependent2CTD_human
HgeneCLEC16AC0026769Multiple Sclerosis2CTD_human
HgeneCLEC16AC0162538Immunoglobulin A deficiency (disorder)2CTD_human
HgeneCLEC16AC0205734Diabetes, Autoimmune2CTD_human
HgeneCLEC16AC0342302Brittle diabetes2CTD_human
HgeneCLEC16AC0751324Multiple Sclerosis, Acute Fulminating2CTD_human
HgeneCLEC16AC3837958Diabetes Mellitus, Ketosis-Prone2CTD_human
HgeneCLEC16AC4554117Diabetes Mellitus, Sudden-Onset2CTD_human
HgeneCLEC16AC0001403Addison Disease1CTD_human
HgeneCLEC16AC0008312Primary biliary cirrhosis1CTD_human
HgeneCLEC16AC0023892Biliary cirrhosis1CTD_human
HgeneCLEC16AC0024141Lupus Erythematosus, Systemic1CTD_human
HgeneCLEC16AC0238065Secondary Biliary Cholangitis1CTD_human
HgeneCLEC16AC0242380Libman-Sacks Disease1CTD_human
HgeneCLEC16AC4551595Biliary Cirrhosis, Primary, 11CTD_human