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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:KLHL18-TEX264 (FusionGDB2 ID:HG23276TG51368)

Fusion Gene Summary for KLHL18-TEX264

check button Fusion gene summary
Fusion gene informationFusion gene name: KLHL18-TEX264
Fusion gene ID: hg23276tg51368
HgeneTgene
Gene symbol

KLHL18

TEX264

Gene ID

23276

51368

Gene namekelch like family member 18testis expressed 264, ER-phagy receptor
Synonyms-ZSIG11
Cytomap('KLHL18')('TEX264')

3p21.31

3p21.2

Type of geneprotein-codingprotein-coding
Descriptionkelch-like protein 18testis-expressed protein 264testis expressed 264testis expressed gene 264testis-expressed sequence 264 protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000483201, ENST00000232766, 
ENST00000455924, 
Fusion gene scores* DoF score4 X 1 X 4=165 X 7 X 5=175
# samples 56
** MAII scorelog2(5/16*10)=1.64385618977472
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(6/175*10)=-1.54432051622381
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KLHL18 [Title/Abstract] AND TEX264 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKLHL18(47324584)-TEX264(51718429), # samples:2
Anticipated loss of major functional domain due to fusion event.KLHL18-TEX264 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
KLHL18-TEX264 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
KLHL18-TEX264 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
KLHL18-TEX264 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneKLHL18

GO:0016567

protein ubiquitination

23213400


check buttonFusion gene breakpoints across KLHL18 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across TEX264 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A3KC-01AKLHL18chr3

47324584

-TEX264chr3

51708287

+
ChimerDB4BRCATCGA-A2-A3KC-01AKLHL18chr3

47324584

+TEX264chr3

51718429

+
ChimerDB4BRCATCGA-A2-A3KCKLHL18chr3

47324584

+TEX264chr3

51708286

+
ChimerDB4BRCATCGA-A2-A3KCKLHL18chr3

47324584

+TEX264chr3

51718428

+


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Fusion Gene ORF analysis for KLHL18-TEX264

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000483201ENST00000341333KLHL18chr3

47324584

+TEX264chr3

51718429

+
3UTR-3CDSENST00000483201ENST00000341333KLHL18chr3

47324584

+TEX264chr3

51718428

+
3UTR-3CDSENST00000483201ENST00000395057KLHL18chr3

47324584

+TEX264chr3

51718429

+
3UTR-3CDSENST00000483201ENST00000395057KLHL18chr3

47324584

+TEX264chr3

51718428

+
3UTR-3CDSENST00000483201ENST00000415259KLHL18chr3

47324584

+TEX264chr3

51718429

+
3UTR-3CDSENST00000483201ENST00000415259KLHL18chr3

47324584

+TEX264chr3

51718428

+
3UTR-3CDSENST00000483201ENST00000416589KLHL18chr3

47324584

+TEX264chr3

51718429

+
3UTR-3CDSENST00000483201ENST00000416589KLHL18chr3

47324584

+TEX264chr3

51718428

+
3UTR-3CDSENST00000483201ENST00000457573KLHL18chr3

47324584

+TEX264chr3

51718429

+
3UTR-3CDSENST00000483201ENST00000457573KLHL18chr3

47324584

+TEX264chr3

51718428

+
3UTR-3UTRENST00000483201ENST00000463857KLHL18chr3

47324584

+TEX264chr3

51718429

+
3UTR-3UTRENST00000483201ENST00000463857KLHL18chr3

47324584

+TEX264chr3

51718428

+
3UTR-5UTRENST00000483201ENST00000341333KLHL18chr3

47324584

-TEX264chr3

51708287

+
3UTR-5UTRENST00000483201ENST00000341333KLHL18chr3

47324584

+TEX264chr3

51708286

+
3UTR-5UTRENST00000483201ENST00000395057KLHL18chr3

47324584

-TEX264chr3

51708287

+
3UTR-5UTRENST00000483201ENST00000395057KLHL18chr3

47324584

+TEX264chr3

51708286

+
3UTR-5UTRENST00000483201ENST00000415259KLHL18chr3

47324584

-TEX264chr3

51708287

+
3UTR-5UTRENST00000483201ENST00000415259KLHL18chr3

47324584

+TEX264chr3

51708286

+
3UTR-5UTRENST00000483201ENST00000416589KLHL18chr3

47324584

-TEX264chr3

51708287

+
3UTR-5UTRENST00000483201ENST00000416589KLHL18chr3

47324584

+TEX264chr3

51708286

+
3UTR-5UTRENST00000483201ENST00000457573KLHL18chr3

47324584

-TEX264chr3

51708287

+
3UTR-5UTRENST00000483201ENST00000457573KLHL18chr3

47324584

+TEX264chr3

51708286

+
3UTR-intronENST00000483201ENST00000463857KLHL18chr3

47324584

-TEX264chr3

51708287

+
3UTR-intronENST00000483201ENST00000463857KLHL18chr3

47324584

+TEX264chr3

51708286

+
5CDS-3UTRENST00000232766ENST00000463857KLHL18chr3

47324584

+TEX264chr3

51718429

+
5CDS-3UTRENST00000232766ENST00000463857KLHL18chr3

47324584

+TEX264chr3

51718428

+
5CDS-5UTRENST00000232766ENST00000341333KLHL18chr3

47324584

-TEX264chr3

51708287

+
5CDS-5UTRENST00000232766ENST00000341333KLHL18chr3

47324584

+TEX264chr3

51708286

+
5CDS-5UTRENST00000232766ENST00000395057KLHL18chr3

47324584

-TEX264chr3

51708287

+
5CDS-5UTRENST00000232766ENST00000395057KLHL18chr3

47324584

+TEX264chr3

51708286

+
5CDS-5UTRENST00000232766ENST00000415259KLHL18chr3

47324584

-TEX264chr3

51708287

+
5CDS-5UTRENST00000232766ENST00000415259KLHL18chr3

47324584

+TEX264chr3

51708286

+
5CDS-5UTRENST00000232766ENST00000416589KLHL18chr3

47324584

-TEX264chr3

51708287

+
5CDS-5UTRENST00000232766ENST00000416589KLHL18chr3

47324584

+TEX264chr3

51708286

+
5CDS-5UTRENST00000232766ENST00000457573KLHL18chr3

47324584

-TEX264chr3

51708287

+
5CDS-5UTRENST00000232766ENST00000457573KLHL18chr3

47324584

+TEX264chr3

51708286

+
5CDS-intronENST00000232766ENST00000463857KLHL18chr3

47324584

-TEX264chr3

51708287

+
5CDS-intronENST00000232766ENST00000463857KLHL18chr3

47324584

+TEX264chr3

51708286

+
5UTR-3CDSENST00000455924ENST00000341333KLHL18chr3

47324584

+TEX264chr3

51718429

+
5UTR-3CDSENST00000455924ENST00000341333KLHL18chr3

47324584

+TEX264chr3

51718428

+
5UTR-3CDSENST00000455924ENST00000395057KLHL18chr3

47324584

+TEX264chr3

51718429

+
5UTR-3CDSENST00000455924ENST00000395057KLHL18chr3

47324584

+TEX264chr3

51718428

+
5UTR-3CDSENST00000455924ENST00000415259KLHL18chr3

47324584

+TEX264chr3

51718429

+
5UTR-3CDSENST00000455924ENST00000415259KLHL18chr3

47324584

+TEX264chr3

51718428

+
5UTR-3CDSENST00000455924ENST00000416589KLHL18chr3

47324584

+TEX264chr3

51718429

+
5UTR-3CDSENST00000455924ENST00000416589KLHL18chr3

47324584

+TEX264chr3

51718428

+
5UTR-3CDSENST00000455924ENST00000457573KLHL18chr3

47324584

+TEX264chr3

51718429

+
5UTR-3CDSENST00000455924ENST00000457573KLHL18chr3

47324584

+TEX264chr3

51718428

+
5UTR-3UTRENST00000455924ENST00000463857KLHL18chr3

47324584

+TEX264chr3

51718429

+
5UTR-3UTRENST00000455924ENST00000463857KLHL18chr3

47324584

+TEX264chr3

51718428

+
5UTR-5UTRENST00000455924ENST00000341333KLHL18chr3

47324584

-TEX264chr3

51708287

+
5UTR-5UTRENST00000455924ENST00000341333KLHL18chr3

47324584

+TEX264chr3

51708286

+
5UTR-5UTRENST00000455924ENST00000395057KLHL18chr3

47324584

-TEX264chr3

51708287

+
5UTR-5UTRENST00000455924ENST00000395057KLHL18chr3

47324584

+TEX264chr3

51708286

+
5UTR-5UTRENST00000455924ENST00000415259KLHL18chr3

47324584

-TEX264chr3

51708287

+
5UTR-5UTRENST00000455924ENST00000415259KLHL18chr3

47324584

+TEX264chr3

51708286

+
5UTR-5UTRENST00000455924ENST00000416589KLHL18chr3

47324584

-TEX264chr3

51708287

+
5UTR-5UTRENST00000455924ENST00000416589KLHL18chr3

47324584

+TEX264chr3

51708286

+
5UTR-5UTRENST00000455924ENST00000457573KLHL18chr3

47324584

-TEX264chr3

51708287

+
5UTR-5UTRENST00000455924ENST00000457573KLHL18chr3

47324584

+TEX264chr3

51708286

+
5UTR-intronENST00000455924ENST00000463857KLHL18chr3

47324584

-TEX264chr3

51708287

+
5UTR-intronENST00000455924ENST00000463857KLHL18chr3

47324584

+TEX264chr3

51708286

+
In-frameENST00000232766ENST00000341333KLHL18chr3

47324584

+TEX264chr3

51718429

+
In-frameENST00000232766ENST00000341333KLHL18chr3

47324584

+TEX264chr3

51718428

+
In-frameENST00000232766ENST00000395057KLHL18chr3

47324584

+TEX264chr3

51718429

+
In-frameENST00000232766ENST00000395057KLHL18chr3

47324584

+TEX264chr3

51718428

+
In-frameENST00000232766ENST00000415259KLHL18chr3

47324584

+TEX264chr3

51718429

+
In-frameENST00000232766ENST00000415259KLHL18chr3

47324584

+TEX264chr3

51718428

+
In-frameENST00000232766ENST00000416589KLHL18chr3

47324584

+TEX264chr3

51718429

+
In-frameENST00000232766ENST00000416589KLHL18chr3

47324584

+TEX264chr3

51718428

+
In-frameENST00000232766ENST00000457573KLHL18chr3

47324584

+TEX264chr3

51718429

+
In-frameENST00000232766ENST00000457573KLHL18chr3

47324584

+TEX264chr3

51718428

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000232766KLHL18chr347324584+ENST00000457573TEX264chr351718429+11391492832276
ENST00000232766KLHL18chr347324584+ENST00000341333TEX264chr351718429+11401492832276
ENST00000232766KLHL18chr347324584+ENST00000415259TEX264chr351718429+11001492832276
ENST00000232766KLHL18chr347324584+ENST00000395057TEX264chr351718429+11381492832276
ENST00000232766KLHL18chr347324584+ENST00000416589TEX264chr351718429+11341492832276
ENST00000232766KLHL18chr347324584+ENST00000457573TEX264chr351718428+11391492832276
ENST00000232766KLHL18chr347324584+ENST00000341333TEX264chr351718428+11401492832276
ENST00000232766KLHL18chr347324584+ENST00000415259TEX264chr351718428+11001492832276
ENST00000232766KLHL18chr347324584+ENST00000395057TEX264chr351718428+11381492832276
ENST00000232766KLHL18chr347324584+ENST00000416589TEX264chr351718428+11341492832276

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000232766ENST00000457573KLHL18chr347324584+TEX264chr351718429+0.014608990.985391
ENST00000232766ENST00000341333KLHL18chr347324584+TEX264chr351718429+0.0147059340.985294
ENST00000232766ENST00000415259KLHL18chr347324584+TEX264chr351718429+0.0137830950.9862169
ENST00000232766ENST00000395057KLHL18chr347324584+TEX264chr351718429+0.0146199480.98538
ENST00000232766ENST00000416589KLHL18chr347324584+TEX264chr351718429+0.0141074520.9858926
ENST00000232766ENST00000457573KLHL18chr347324584+TEX264chr351718428+0.014608990.985391
ENST00000232766ENST00000341333KLHL18chr347324584+TEX264chr351718428+0.0147059340.985294
ENST00000232766ENST00000415259KLHL18chr347324584+TEX264chr351718428+0.0137830950.9862169
ENST00000232766ENST00000395057KLHL18chr347324584+TEX264chr351718428+0.0146199480.98538
ENST00000232766ENST00000416589KLHL18chr347324584+TEX264chr351718428+0.0141074520.9858926

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Fusion Genomic Features for KLHL18-TEX264


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
KLHL18chr347324584+TEX264chr351718428+2.23E-101
KLHL18chr347324584+TEX264chr351708286+7.13E-101
KLHL18chr347324584+TEX264chr351718428+2.23E-101
KLHL18chr347324584+TEX264chr351718428+2.23E-101
KLHL18chr347324584+TEX264chr351708286+7.13E-101
KLHL18chr347324584+TEX264chr351718428+2.23E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for KLHL18-TEX264


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:47324584/chr3:51718429)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTEX264chr3:47324584chr3:51718428ENST0000034133315273_27686314.0MotifLIR motif
TgeneTEX264chr3:47324584chr3:51718428ENST0000039505715273_27686314.0MotifLIR motif
TgeneTEX264chr3:47324584chr3:51718428ENST0000041525915273_27686314.0MotifLIR motif
TgeneTEX264chr3:47324584chr3:51718428ENST0000041658915273_27686314.0MotifLIR motif
TgeneTEX264chr3:47324584chr3:51718428ENST0000045757326273_27686314.0MotifLIR motif
TgeneTEX264chr3:47324584chr3:51718429ENST0000034133315273_27686314.0MotifLIR motif
TgeneTEX264chr3:47324584chr3:51718429ENST0000039505715273_27686314.0MotifLIR motif
TgeneTEX264chr3:47324584chr3:51718429ENST0000041525915273_27686314.0MotifLIR motif
TgeneTEX264chr3:47324584chr3:51718429ENST0000041658915273_27686314.0MotifLIR motif
TgeneTEX264chr3:47324584chr3:51718429ENST0000045757326273_27686314.0MotifLIR motif
TgeneTEX264chr3:47324584chr3:51718428ENST0000034133315193_31386314.0RegionIntrinsically disordered region (IDR)
TgeneTEX264chr3:47324584chr3:51718428ENST0000039505715193_31386314.0RegionIntrinsically disordered region (IDR)
TgeneTEX264chr3:47324584chr3:51718428ENST0000041525915193_31386314.0RegionIntrinsically disordered region (IDR)
TgeneTEX264chr3:47324584chr3:51718428ENST0000041658915193_31386314.0RegionIntrinsically disordered region (IDR)
TgeneTEX264chr3:47324584chr3:51718428ENST0000045757326193_31386314.0RegionIntrinsically disordered region (IDR)
TgeneTEX264chr3:47324584chr3:51718429ENST0000034133315193_31386314.0RegionIntrinsically disordered region (IDR)
TgeneTEX264chr3:47324584chr3:51718429ENST0000039505715193_31386314.0RegionIntrinsically disordered region (IDR)
TgeneTEX264chr3:47324584chr3:51718429ENST0000041525915193_31386314.0RegionIntrinsically disordered region (IDR)
TgeneTEX264chr3:47324584chr3:51718429ENST0000041658915193_31386314.0RegionIntrinsically disordered region (IDR)
TgeneTEX264chr3:47324584chr3:51718429ENST0000045757326193_31386314.0RegionIntrinsically disordered region (IDR)

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKLHL18chr3:47324584chr3:51718428ENST00000232766+110140_24243575.0DomainNote=BACK
HgeneKLHL18chr3:47324584chr3:51718428ENST00000232766+11066_10543575.0DomainBTB
HgeneKLHL18chr3:47324584chr3:51718429ENST00000232766+110140_24243575.0DomainNote=BACK
HgeneKLHL18chr3:47324584chr3:51718429ENST00000232766+11066_10543575.0DomainBTB
HgeneKLHL18chr3:47324584chr3:51718428ENST00000232766+110289_33643575.0RepeatNote=Kelch 1
HgeneKLHL18chr3:47324584chr3:51718428ENST00000232766+110337_38343575.0RepeatNote=Kelch 2
HgeneKLHL18chr3:47324584chr3:51718428ENST00000232766+110384_43043575.0RepeatNote=Kelch 3
HgeneKLHL18chr3:47324584chr3:51718428ENST00000232766+110432_47743575.0RepeatNote=Kelch 4
HgeneKLHL18chr3:47324584chr3:51718428ENST00000232766+110479_52443575.0RepeatNote=Kelch 5
HgeneKLHL18chr3:47324584chr3:51718428ENST00000232766+110525_57143575.0RepeatNote=Kelch 6
HgeneKLHL18chr3:47324584chr3:51718429ENST00000232766+110289_33643575.0RepeatNote=Kelch 1
HgeneKLHL18chr3:47324584chr3:51718429ENST00000232766+110337_38343575.0RepeatNote=Kelch 2
HgeneKLHL18chr3:47324584chr3:51718429ENST00000232766+110384_43043575.0RepeatNote=Kelch 3
HgeneKLHL18chr3:47324584chr3:51718429ENST00000232766+110432_47743575.0RepeatNote=Kelch 4
HgeneKLHL18chr3:47324584chr3:51718429ENST00000232766+110479_52443575.0RepeatNote=Kelch 5
HgeneKLHL18chr3:47324584chr3:51718429ENST00000232766+110525_57143575.0RepeatNote=Kelch 6
TgeneTEX264chr3:47324584chr3:51718428ENST00000341333151_686314.0Topological domainLumenal
TgeneTEX264chr3:47324584chr3:51718428ENST000003413331532_31386314.0Topological domainCytoplasmic
TgeneTEX264chr3:47324584chr3:51718428ENST00000395057151_686314.0Topological domainLumenal
TgeneTEX264chr3:47324584chr3:51718428ENST000003950571532_31386314.0Topological domainCytoplasmic
TgeneTEX264chr3:47324584chr3:51718428ENST00000415259151_686314.0Topological domainLumenal
TgeneTEX264chr3:47324584chr3:51718428ENST000004152591532_31386314.0Topological domainCytoplasmic
TgeneTEX264chr3:47324584chr3:51718428ENST00000416589151_686314.0Topological domainLumenal
TgeneTEX264chr3:47324584chr3:51718428ENST000004165891532_31386314.0Topological domainCytoplasmic
TgeneTEX264chr3:47324584chr3:51718428ENST00000457573261_686314.0Topological domainLumenal
TgeneTEX264chr3:47324584chr3:51718428ENST000004575732632_31386314.0Topological domainCytoplasmic
TgeneTEX264chr3:47324584chr3:51718429ENST00000341333151_686314.0Topological domainLumenal
TgeneTEX264chr3:47324584chr3:51718429ENST000003413331532_31386314.0Topological domainCytoplasmic
TgeneTEX264chr3:47324584chr3:51718429ENST00000395057151_686314.0Topological domainLumenal
TgeneTEX264chr3:47324584chr3:51718429ENST000003950571532_31386314.0Topological domainCytoplasmic
TgeneTEX264chr3:47324584chr3:51718429ENST00000415259151_686314.0Topological domainLumenal
TgeneTEX264chr3:47324584chr3:51718429ENST000004152591532_31386314.0Topological domainCytoplasmic
TgeneTEX264chr3:47324584chr3:51718429ENST00000416589151_686314.0Topological domainLumenal
TgeneTEX264chr3:47324584chr3:51718429ENST000004165891532_31386314.0Topological domainCytoplasmic
TgeneTEX264chr3:47324584chr3:51718429ENST00000457573261_686314.0Topological domainLumenal
TgeneTEX264chr3:47324584chr3:51718429ENST000004575732632_31386314.0Topological domainCytoplasmic
TgeneTEX264chr3:47324584chr3:51718428ENST00000341333157_3186314.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneTEX264chr3:47324584chr3:51718428ENST00000395057157_3186314.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneTEX264chr3:47324584chr3:51718428ENST00000415259157_3186314.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneTEX264chr3:47324584chr3:51718428ENST00000416589157_3186314.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneTEX264chr3:47324584chr3:51718428ENST00000457573267_3186314.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneTEX264chr3:47324584chr3:51718429ENST00000341333157_3186314.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneTEX264chr3:47324584chr3:51718429ENST00000395057157_3186314.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneTEX264chr3:47324584chr3:51718429ENST00000415259157_3186314.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneTEX264chr3:47324584chr3:51718429ENST00000416589157_3186314.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneTEX264chr3:47324584chr3:51718429ENST00000457573267_3186314.0TransmembraneHelical%3B Signal-anchor for type III membrane protein


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Fusion Gene Sequence for KLHL18-TEX264


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>42949_42949_1_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718428_ENST00000341333_length(transcript)=1140nt_BP=149nt
AGTTGCAGCGGCCGGGGAAGATGGTGGAGGACGGCGCGGAGGAGCTGGAGGATCTGGTGCACTTCTCCGTGTCTGAGTTGCCTAGTCGCG
GCTACGGCGTCATGGAGGAGATCCGGCGGCAGGGCAAGCTGTGCGACGTGACCCTCAAGGTGCCCCCTGATAAGTGCCGATGTGCCGTGG
GCAGCATCCTGAGTGAAGGTGAGGAATCGCCCTCCCCTGAGCTCATCGACCTCTACCAGAAATTTGGCTTCAAGGTGTTCTCCTTCCCGG
CACCCAGCCATGTGGTGACAGCCACCTTCCCCTACACCACCATTCTGTCCATCTGGCTGGCTACCCGCCGTGTCCATCCTGCCTTGGACA
CCTACATCAAGGAGCGGAAGCTGTGTGCCTATCCTCGGCTGGAGATCTACCAGGAAGACCAGATCCATTTCATGTGCCCACTGGCACGGC
AGGGAGACTTCTATGTGCCTGAGATGAAGGAGACAGAGTGGAAATGGCGGGGGCTTGTGGAGGCCATTGACACCCAGGTGGATGGCACAG
GAGCTGACACAATGAGTGACACGAGTTCTGTAAGCTTGGAAGTGAGCCCTGGCAGCCGGGAGACTTCAGCTGCCACACTGTCACCTGGGG
CGAGCAGCCGTGGCTGGGATGACGGTGACACCCGCAGCGAGCACAGCTACAGCGAGTCAGGTGCCAGCGGCTCCTCTTTTGAGGAGCTGG
ACTTGGAGGGCGAGGGGCCCTTAGGGGAGTCACGGCTGGACCCTGGGACTGAGCCCCTGGGGACTACCAAGTGGCTCTGGGAGCCCACTG
CCCCTGAGAAGGGCAAGGAGTAACCCATGGCCTGCACCCTCCTGCAGTGCAGTTGCTGAGGAACTGAGCAGACTCTCCAGCAGACTCTCC
AGCCCTCTTCCTCCTTCCTCTGGGGGAGGAGGGGTTCCTGAGGGACCTGACTTCCCCTGCTCCAGGCCTCTTGCTAAGCCTTCTCCTCAC
TGCCCTTTAGGCTCCCAGGGCCAGAGGAGCCAGGGACTATTTTCTGCACCAGCCCCCAGGGCTGCCACCCCTGTTGTGTCTTTTTTTCAG
ACTCACAGTGGAGCTTCCAGGACCCAGAATAAAGCCAATGATTTACTTGTTTCACCTGGA

>42949_42949_1_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718428_ENST00000341333_length(amino acids)=276AA_BP=49
LQRPGKMVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKVPPDKCRCAVGSILSEGEESPSPELIDLYQKFGFKVFSFPA
PSHVVTATFPYTTILSIWLATRRVHPALDTYIKERKLCAYPRLEIYQEDQIHFMCPLARQGDFYVPEMKETEWKWRGLVEAIDTQVDGTG
ADTMSDTSSVSLEVSPGSRETSAATLSPGASSRGWDDGDTRSEHSYSESGASGSSFEELDLEGEGPLGESRLDPGTEPLGTTKWLWEPTA
PEKGKE

--------------------------------------------------------------
>42949_42949_2_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718428_ENST00000395057_length(transcript)=1138nt_BP=149nt
AGTTGCAGCGGCCGGGGAAGATGGTGGAGGACGGCGCGGAGGAGCTGGAGGATCTGGTGCACTTCTCCGTGTCTGAGTTGCCTAGTCGCG
GCTACGGCGTCATGGAGGAGATCCGGCGGCAGGGCAAGCTGTGCGACGTGACCCTCAAGGTGCCCCCTGATAAGTGCCGATGTGCCGTGG
GCAGCATCCTGAGTGAAGGTGAGGAATCGCCCTCCCCTGAGCTCATCGACCTCTACCAGAAATTTGGCTTCAAGGTGTTCTCCTTCCCGG
CACCCAGCCATGTGGTGACAGCCACCTTCCCCTACACCACCATTCTGTCCATCTGGCTGGCTACCCGCCGTGTCCATCCTGCCTTGGACA
CCTACATCAAGGAGCGGAAGCTGTGTGCCTATCCTCGGCTGGAGATCTACCAGGAAGACCAGATCCATTTCATGTGCCCACTGGCACGGC
AGGGAGACTTCTATGTGCCTGAGATGAAGGAGACAGAGTGGAAATGGCGGGGGCTTGTGGAGGCCATTGACACCCAGGTGGATGGCACAG
GAGCTGACACAATGAGTGACACGAGTTCTGTAAGCTTGGAAGTGAGCCCTGGCAGCCGGGAGACTTCAGCTGCCACACTGTCACCTGGGG
CGAGCAGCCGTGGCTGGGATGACGGTGACACCCGCAGCGAGCACAGCTACAGCGAGTCAGGTGCCAGCGGCTCCTCTTTTGAGGAGCTGG
ACTTGGAGGGCGAGGGGCCCTTAGGGGAGTCACGGCTGGACCCTGGGACTGAGCCCCTGGGGACTACCAAGTGGCTCTGGGAGCCCACTG
CCCCTGAGAAGGGCAAGGAGTAACCCATGGCCTGCACCCTCCTGCAGTGCAGTTGCTGAGGAACTGAGCAGACTCTCCAGCAGACTCTCC
AGCCCTCTTCCTCCTTCCTCTGGGGGAGGAGGGGTTCCTGAGGGACCTGACTTCCCCTGCTCCAGGCCTCTTGCTAAGCCTTCTCCTCAC
TGCCCTTTAGGCTCCCAGGGCCAGAGGAGCCAGGGACTATTTTCTGCACCAGCCCCCAGGGCTGCCACCCCTGTTGTGTCTTTTTTTCAG
ACTCACAGTGGAGCTTCCAGGACCCAGAATAAAGCCAATGATTTACTTGTTTCACCTG

>42949_42949_2_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718428_ENST00000395057_length(amino acids)=276AA_BP=49
LQRPGKMVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKVPPDKCRCAVGSILSEGEESPSPELIDLYQKFGFKVFSFPA
PSHVVTATFPYTTILSIWLATRRVHPALDTYIKERKLCAYPRLEIYQEDQIHFMCPLARQGDFYVPEMKETEWKWRGLVEAIDTQVDGTG
ADTMSDTSSVSLEVSPGSRETSAATLSPGASSRGWDDGDTRSEHSYSESGASGSSFEELDLEGEGPLGESRLDPGTEPLGTTKWLWEPTA
PEKGKE

--------------------------------------------------------------
>42949_42949_3_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718428_ENST00000415259_length(transcript)=1100nt_BP=149nt
AGTTGCAGCGGCCGGGGAAGATGGTGGAGGACGGCGCGGAGGAGCTGGAGGATCTGGTGCACTTCTCCGTGTCTGAGTTGCCTAGTCGCG
GCTACGGCGTCATGGAGGAGATCCGGCGGCAGGGCAAGCTGTGCGACGTGACCCTCAAGGTGCCCCCTGATAAGTGCCGATGTGCCGTGG
GCAGCATCCTGAGTGAAGGTGAGGAATCGCCCTCCCCTGAGCTCATCGACCTCTACCAGAAATTTGGCTTCAAGGTGTTCTCCTTCCCGG
CACCCAGCCATGTGGTGACAGCCACCTTCCCCTACACCACCATTCTGTCCATCTGGCTGGCTACCCGCCGTGTCCATCCTGCCTTGGACA
CCTACATCAAGGAGCGGAAGCTGTGTGCCTATCCTCGGCTGGAGATCTACCAGGAAGACCAGATCCATTTCATGTGCCCACTGGCACGGC
AGGGAGACTTCTATGTGCCTGAGATGAAGGAGACAGAGTGGAAATGGCGGGGGCTTGTGGAGGCCATTGACACCCAGGTGGATGGCACAG
GAGCTGACACAATGAGTGACACGAGTTCTGTAAGCTTGGAAGTGAGCCCTGGCAGCCGGGAGACTTCAGCTGCCACACTGTCACCTGGGG
CGAGCAGCCGTGGCTGGGATGACGGTGACACCCGCAGCGAGCACAGCTACAGCGAGTCAGGTGCCAGCGGCTCCTCTTTTGAGGAGCTGG
ACTTGGAGGGCGAGGGGCCCTTAGGGGAGTCACGGCTGGACCCTGGGACTGAGCCCCTGGGGACTACCAAGTGGCTCTGGGAGCCCACTG
CCCCTGAGAAGGGCAAGGAGTAACCCATGGCCTGCACCCTCCTGCAGTGCAGTTGCTGAGGAACTGAGCAGACTCTCCAGCAGACTCTCC
AGCCCTCTTCCTCCTTCCTCTGGGGGAGGAGGGGTTCCTGAGGGACCTGACTTCCCCTGCTCCAGGCCTCTTGCTAAGCCTTCTCCTCAC
TGCCCTTTAGGCTCCCAGGGCCAGAGGAGCCAGGGACTATTTTCTGCACCAGCCCCCAGGGCTGCCACCCCTGTTGTGTCTTTTTTTCAG
ACTCACAGTGGAGCTTCCAG

>42949_42949_3_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718428_ENST00000415259_length(amino acids)=276AA_BP=49
LQRPGKMVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKVPPDKCRCAVGSILSEGEESPSPELIDLYQKFGFKVFSFPA
PSHVVTATFPYTTILSIWLATRRVHPALDTYIKERKLCAYPRLEIYQEDQIHFMCPLARQGDFYVPEMKETEWKWRGLVEAIDTQVDGTG
ADTMSDTSSVSLEVSPGSRETSAATLSPGASSRGWDDGDTRSEHSYSESGASGSSFEELDLEGEGPLGESRLDPGTEPLGTTKWLWEPTA
PEKGKE

--------------------------------------------------------------
>42949_42949_4_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718428_ENST00000416589_length(transcript)=1134nt_BP=149nt
AGTTGCAGCGGCCGGGGAAGATGGTGGAGGACGGCGCGGAGGAGCTGGAGGATCTGGTGCACTTCTCCGTGTCTGAGTTGCCTAGTCGCG
GCTACGGCGTCATGGAGGAGATCCGGCGGCAGGGCAAGCTGTGCGACGTGACCCTCAAGGTGCCCCCTGATAAGTGCCGATGTGCCGTGG
GCAGCATCCTGAGTGAAGGTGAGGAATCGCCCTCCCCTGAGCTCATCGACCTCTACCAGAAATTTGGCTTCAAGGTGTTCTCCTTCCCGG
CACCCAGCCATGTGGTGACAGCCACCTTCCCCTACACCACCATTCTGTCCATCTGGCTGGCTACCCGCCGTGTCCATCCTGCCTTGGACA
CCTACATCAAGGAGCGGAAGCTGTGTGCCTATCCTCGGCTGGAGATCTACCAGGAAGACCAGATCCATTTCATGTGCCCACTGGCACGGC
AGGGAGACTTCTATGTGCCTGAGATGAAGGAGACAGAGTGGAAATGGCGGGGGCTTGTGGAGGCCATTGACACCCAGGTGGATGGCACAG
GAGCTGACACAATGAGTGACACGAGTTCTGTAAGCTTGGAAGTGAGCCCTGGCAGCCGGGAGACTTCAGCTGCCACACTGTCACCTGGGG
CGAGCAGCCGTGGCTGGGATGACGGTGACACCCGCAGCGAGCACAGCTACAGCGAGTCAGGTGCCAGCGGCTCCTCTTTTGAGGAGCTGG
ACTTGGAGGGCGAGGGGCCCTTAGGGGAGTCACGGCTGGACCCTGGGACTGAGCCCCTGGGGACTACCAAGTGGCTCTGGGAGCCCACTG
CCCCTGAGAAGGGCAAGGAGTAACCCATGGCCTGCACCCTCCTGCAGTGCAGTTGCTGAGGAACTGAGCAGACTCTCCAGCAGACTCTCC
AGCCCTCTTCCTCCTTCCTCTGGGGGAGGAGGGGTTCCTGAGGGACCTGACTTCCCCTGCTCCAGGCCTCTTGCTAAGCCTTCTCCTCAC
TGCCCTTTAGGCTCCCAGGGCCAGAGGAGCCAGGGACTATTTTCTGCACCAGCCCCCAGGGCTGCCACCCCTGTTGTGTCTTTTTTTCAG
ACTCACAGTGGAGCTTCCAGGACCCAGAATAAAGCCAATGATTTACTTGTTTCA

>42949_42949_4_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718428_ENST00000416589_length(amino acids)=276AA_BP=49
LQRPGKMVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKVPPDKCRCAVGSILSEGEESPSPELIDLYQKFGFKVFSFPA
PSHVVTATFPYTTILSIWLATRRVHPALDTYIKERKLCAYPRLEIYQEDQIHFMCPLARQGDFYVPEMKETEWKWRGLVEAIDTQVDGTG
ADTMSDTSSVSLEVSPGSRETSAATLSPGASSRGWDDGDTRSEHSYSESGASGSSFEELDLEGEGPLGESRLDPGTEPLGTTKWLWEPTA
PEKGKE

--------------------------------------------------------------
>42949_42949_5_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718428_ENST00000457573_length(transcript)=1139nt_BP=149nt
AGTTGCAGCGGCCGGGGAAGATGGTGGAGGACGGCGCGGAGGAGCTGGAGGATCTGGTGCACTTCTCCGTGTCTGAGTTGCCTAGTCGCG
GCTACGGCGTCATGGAGGAGATCCGGCGGCAGGGCAAGCTGTGCGACGTGACCCTCAAGGTGCCCCCTGATAAGTGCCGATGTGCCGTGG
GCAGCATCCTGAGTGAAGGTGAGGAATCGCCCTCCCCTGAGCTCATCGACCTCTACCAGAAATTTGGCTTCAAGGTGTTCTCCTTCCCGG
CACCCAGCCATGTGGTGACAGCCACCTTCCCCTACACCACCATTCTGTCCATCTGGCTGGCTACCCGCCGTGTCCATCCTGCCTTGGACA
CCTACATCAAGGAGCGGAAGCTGTGTGCCTATCCTCGGCTGGAGATCTACCAGGAAGACCAGATCCATTTCATGTGCCCACTGGCACGGC
AGGGAGACTTCTATGTGCCTGAGATGAAGGAGACAGAGTGGAAATGGCGGGGGCTTGTGGAGGCCATTGACACCCAGGTGGATGGCACAG
GAGCTGACACAATGAGTGACACGAGTTCTGTAAGCTTGGAAGTGAGCCCTGGCAGCCGGGAGACTTCAGCTGCCACACTGTCACCTGGGG
CGAGCAGCCGTGGCTGGGATGACGGTGACACCCGCAGCGAGCACAGCTACAGCGAGTCAGGTGCCAGCGGCTCCTCTTTTGAGGAGCTGG
ACTTGGAGGGCGAGGGGCCCTTAGGGGAGTCACGGCTGGACCCTGGGACTGAGCCCCTGGGGACTACCAAGTGGCTCTGGGAGCCCACTG
CCCCTGAGAAGGGCAAGGAGTAACCCATGGCCTGCACCCTCCTGCAGTGCAGTTGCTGAGGAACTGAGCAGACTCTCCAGCAGACTCTCC
AGCCCTCTTCCTCCTTCCTCTGGGGGAGGAGGGGTTCCTGAGGGACCTGACTTCCCCTGCTCCAGGCCTCTTGCTAAGCCTTCTCCTCAC
TGCCCTTTAGGCTCCCAGGGCCAGAGGAGCCAGGGACTATTTTCTGCACCAGCCCCCAGGGCTGCCACCCCTGTTGTGTCTTTTTTTCAG
ACTCACAGTGGAGCTTCCAGGACCCAGAATAAAGCCAATGATTTACTTGTTTCACCTGG

>42949_42949_5_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718428_ENST00000457573_length(amino acids)=276AA_BP=49
LQRPGKMVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKVPPDKCRCAVGSILSEGEESPSPELIDLYQKFGFKVFSFPA
PSHVVTATFPYTTILSIWLATRRVHPALDTYIKERKLCAYPRLEIYQEDQIHFMCPLARQGDFYVPEMKETEWKWRGLVEAIDTQVDGTG
ADTMSDTSSVSLEVSPGSRETSAATLSPGASSRGWDDGDTRSEHSYSESGASGSSFEELDLEGEGPLGESRLDPGTEPLGTTKWLWEPTA
PEKGKE

--------------------------------------------------------------
>42949_42949_6_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718429_ENST00000341333_length(transcript)=1140nt_BP=149nt
AGTTGCAGCGGCCGGGGAAGATGGTGGAGGACGGCGCGGAGGAGCTGGAGGATCTGGTGCACTTCTCCGTGTCTGAGTTGCCTAGTCGCG
GCTACGGCGTCATGGAGGAGATCCGGCGGCAGGGCAAGCTGTGCGACGTGACCCTCAAGGTGCCCCCTGATAAGTGCCGATGTGCCGTGG
GCAGCATCCTGAGTGAAGGTGAGGAATCGCCCTCCCCTGAGCTCATCGACCTCTACCAGAAATTTGGCTTCAAGGTGTTCTCCTTCCCGG
CACCCAGCCATGTGGTGACAGCCACCTTCCCCTACACCACCATTCTGTCCATCTGGCTGGCTACCCGCCGTGTCCATCCTGCCTTGGACA
CCTACATCAAGGAGCGGAAGCTGTGTGCCTATCCTCGGCTGGAGATCTACCAGGAAGACCAGATCCATTTCATGTGCCCACTGGCACGGC
AGGGAGACTTCTATGTGCCTGAGATGAAGGAGACAGAGTGGAAATGGCGGGGGCTTGTGGAGGCCATTGACACCCAGGTGGATGGCACAG
GAGCTGACACAATGAGTGACACGAGTTCTGTAAGCTTGGAAGTGAGCCCTGGCAGCCGGGAGACTTCAGCTGCCACACTGTCACCTGGGG
CGAGCAGCCGTGGCTGGGATGACGGTGACACCCGCAGCGAGCACAGCTACAGCGAGTCAGGTGCCAGCGGCTCCTCTTTTGAGGAGCTGG
ACTTGGAGGGCGAGGGGCCCTTAGGGGAGTCACGGCTGGACCCTGGGACTGAGCCCCTGGGGACTACCAAGTGGCTCTGGGAGCCCACTG
CCCCTGAGAAGGGCAAGGAGTAACCCATGGCCTGCACCCTCCTGCAGTGCAGTTGCTGAGGAACTGAGCAGACTCTCCAGCAGACTCTCC
AGCCCTCTTCCTCCTTCCTCTGGGGGAGGAGGGGTTCCTGAGGGACCTGACTTCCCCTGCTCCAGGCCTCTTGCTAAGCCTTCTCCTCAC
TGCCCTTTAGGCTCCCAGGGCCAGAGGAGCCAGGGACTATTTTCTGCACCAGCCCCCAGGGCTGCCACCCCTGTTGTGTCTTTTTTTCAG
ACTCACAGTGGAGCTTCCAGGACCCAGAATAAAGCCAATGATTTACTTGTTTCACCTGGA

>42949_42949_6_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718429_ENST00000341333_length(amino acids)=276AA_BP=49
LQRPGKMVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKVPPDKCRCAVGSILSEGEESPSPELIDLYQKFGFKVFSFPA
PSHVVTATFPYTTILSIWLATRRVHPALDTYIKERKLCAYPRLEIYQEDQIHFMCPLARQGDFYVPEMKETEWKWRGLVEAIDTQVDGTG
ADTMSDTSSVSLEVSPGSRETSAATLSPGASSRGWDDGDTRSEHSYSESGASGSSFEELDLEGEGPLGESRLDPGTEPLGTTKWLWEPTA
PEKGKE

--------------------------------------------------------------
>42949_42949_7_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718429_ENST00000395057_length(transcript)=1138nt_BP=149nt
AGTTGCAGCGGCCGGGGAAGATGGTGGAGGACGGCGCGGAGGAGCTGGAGGATCTGGTGCACTTCTCCGTGTCTGAGTTGCCTAGTCGCG
GCTACGGCGTCATGGAGGAGATCCGGCGGCAGGGCAAGCTGTGCGACGTGACCCTCAAGGTGCCCCCTGATAAGTGCCGATGTGCCGTGG
GCAGCATCCTGAGTGAAGGTGAGGAATCGCCCTCCCCTGAGCTCATCGACCTCTACCAGAAATTTGGCTTCAAGGTGTTCTCCTTCCCGG
CACCCAGCCATGTGGTGACAGCCACCTTCCCCTACACCACCATTCTGTCCATCTGGCTGGCTACCCGCCGTGTCCATCCTGCCTTGGACA
CCTACATCAAGGAGCGGAAGCTGTGTGCCTATCCTCGGCTGGAGATCTACCAGGAAGACCAGATCCATTTCATGTGCCCACTGGCACGGC
AGGGAGACTTCTATGTGCCTGAGATGAAGGAGACAGAGTGGAAATGGCGGGGGCTTGTGGAGGCCATTGACACCCAGGTGGATGGCACAG
GAGCTGACACAATGAGTGACACGAGTTCTGTAAGCTTGGAAGTGAGCCCTGGCAGCCGGGAGACTTCAGCTGCCACACTGTCACCTGGGG
CGAGCAGCCGTGGCTGGGATGACGGTGACACCCGCAGCGAGCACAGCTACAGCGAGTCAGGTGCCAGCGGCTCCTCTTTTGAGGAGCTGG
ACTTGGAGGGCGAGGGGCCCTTAGGGGAGTCACGGCTGGACCCTGGGACTGAGCCCCTGGGGACTACCAAGTGGCTCTGGGAGCCCACTG
CCCCTGAGAAGGGCAAGGAGTAACCCATGGCCTGCACCCTCCTGCAGTGCAGTTGCTGAGGAACTGAGCAGACTCTCCAGCAGACTCTCC
AGCCCTCTTCCTCCTTCCTCTGGGGGAGGAGGGGTTCCTGAGGGACCTGACTTCCCCTGCTCCAGGCCTCTTGCTAAGCCTTCTCCTCAC
TGCCCTTTAGGCTCCCAGGGCCAGAGGAGCCAGGGACTATTTTCTGCACCAGCCCCCAGGGCTGCCACCCCTGTTGTGTCTTTTTTTCAG
ACTCACAGTGGAGCTTCCAGGACCCAGAATAAAGCCAATGATTTACTTGTTTCACCTG

>42949_42949_7_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718429_ENST00000395057_length(amino acids)=276AA_BP=49
LQRPGKMVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKVPPDKCRCAVGSILSEGEESPSPELIDLYQKFGFKVFSFPA
PSHVVTATFPYTTILSIWLATRRVHPALDTYIKERKLCAYPRLEIYQEDQIHFMCPLARQGDFYVPEMKETEWKWRGLVEAIDTQVDGTG
ADTMSDTSSVSLEVSPGSRETSAATLSPGASSRGWDDGDTRSEHSYSESGASGSSFEELDLEGEGPLGESRLDPGTEPLGTTKWLWEPTA
PEKGKE

--------------------------------------------------------------
>42949_42949_8_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718429_ENST00000415259_length(transcript)=1100nt_BP=149nt
AGTTGCAGCGGCCGGGGAAGATGGTGGAGGACGGCGCGGAGGAGCTGGAGGATCTGGTGCACTTCTCCGTGTCTGAGTTGCCTAGTCGCG
GCTACGGCGTCATGGAGGAGATCCGGCGGCAGGGCAAGCTGTGCGACGTGACCCTCAAGGTGCCCCCTGATAAGTGCCGATGTGCCGTGG
GCAGCATCCTGAGTGAAGGTGAGGAATCGCCCTCCCCTGAGCTCATCGACCTCTACCAGAAATTTGGCTTCAAGGTGTTCTCCTTCCCGG
CACCCAGCCATGTGGTGACAGCCACCTTCCCCTACACCACCATTCTGTCCATCTGGCTGGCTACCCGCCGTGTCCATCCTGCCTTGGACA
CCTACATCAAGGAGCGGAAGCTGTGTGCCTATCCTCGGCTGGAGATCTACCAGGAAGACCAGATCCATTTCATGTGCCCACTGGCACGGC
AGGGAGACTTCTATGTGCCTGAGATGAAGGAGACAGAGTGGAAATGGCGGGGGCTTGTGGAGGCCATTGACACCCAGGTGGATGGCACAG
GAGCTGACACAATGAGTGACACGAGTTCTGTAAGCTTGGAAGTGAGCCCTGGCAGCCGGGAGACTTCAGCTGCCACACTGTCACCTGGGG
CGAGCAGCCGTGGCTGGGATGACGGTGACACCCGCAGCGAGCACAGCTACAGCGAGTCAGGTGCCAGCGGCTCCTCTTTTGAGGAGCTGG
ACTTGGAGGGCGAGGGGCCCTTAGGGGAGTCACGGCTGGACCCTGGGACTGAGCCCCTGGGGACTACCAAGTGGCTCTGGGAGCCCACTG
CCCCTGAGAAGGGCAAGGAGTAACCCATGGCCTGCACCCTCCTGCAGTGCAGTTGCTGAGGAACTGAGCAGACTCTCCAGCAGACTCTCC
AGCCCTCTTCCTCCTTCCTCTGGGGGAGGAGGGGTTCCTGAGGGACCTGACTTCCCCTGCTCCAGGCCTCTTGCTAAGCCTTCTCCTCAC
TGCCCTTTAGGCTCCCAGGGCCAGAGGAGCCAGGGACTATTTTCTGCACCAGCCCCCAGGGCTGCCACCCCTGTTGTGTCTTTTTTTCAG
ACTCACAGTGGAGCTTCCAG

>42949_42949_8_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718429_ENST00000415259_length(amino acids)=276AA_BP=49
LQRPGKMVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKVPPDKCRCAVGSILSEGEESPSPELIDLYQKFGFKVFSFPA
PSHVVTATFPYTTILSIWLATRRVHPALDTYIKERKLCAYPRLEIYQEDQIHFMCPLARQGDFYVPEMKETEWKWRGLVEAIDTQVDGTG
ADTMSDTSSVSLEVSPGSRETSAATLSPGASSRGWDDGDTRSEHSYSESGASGSSFEELDLEGEGPLGESRLDPGTEPLGTTKWLWEPTA
PEKGKE

--------------------------------------------------------------
>42949_42949_9_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718429_ENST00000416589_length(transcript)=1134nt_BP=149nt
AGTTGCAGCGGCCGGGGAAGATGGTGGAGGACGGCGCGGAGGAGCTGGAGGATCTGGTGCACTTCTCCGTGTCTGAGTTGCCTAGTCGCG
GCTACGGCGTCATGGAGGAGATCCGGCGGCAGGGCAAGCTGTGCGACGTGACCCTCAAGGTGCCCCCTGATAAGTGCCGATGTGCCGTGG
GCAGCATCCTGAGTGAAGGTGAGGAATCGCCCTCCCCTGAGCTCATCGACCTCTACCAGAAATTTGGCTTCAAGGTGTTCTCCTTCCCGG
CACCCAGCCATGTGGTGACAGCCACCTTCCCCTACACCACCATTCTGTCCATCTGGCTGGCTACCCGCCGTGTCCATCCTGCCTTGGACA
CCTACATCAAGGAGCGGAAGCTGTGTGCCTATCCTCGGCTGGAGATCTACCAGGAAGACCAGATCCATTTCATGTGCCCACTGGCACGGC
AGGGAGACTTCTATGTGCCTGAGATGAAGGAGACAGAGTGGAAATGGCGGGGGCTTGTGGAGGCCATTGACACCCAGGTGGATGGCACAG
GAGCTGACACAATGAGTGACACGAGTTCTGTAAGCTTGGAAGTGAGCCCTGGCAGCCGGGAGACTTCAGCTGCCACACTGTCACCTGGGG
CGAGCAGCCGTGGCTGGGATGACGGTGACACCCGCAGCGAGCACAGCTACAGCGAGTCAGGTGCCAGCGGCTCCTCTTTTGAGGAGCTGG
ACTTGGAGGGCGAGGGGCCCTTAGGGGAGTCACGGCTGGACCCTGGGACTGAGCCCCTGGGGACTACCAAGTGGCTCTGGGAGCCCACTG
CCCCTGAGAAGGGCAAGGAGTAACCCATGGCCTGCACCCTCCTGCAGTGCAGTTGCTGAGGAACTGAGCAGACTCTCCAGCAGACTCTCC
AGCCCTCTTCCTCCTTCCTCTGGGGGAGGAGGGGTTCCTGAGGGACCTGACTTCCCCTGCTCCAGGCCTCTTGCTAAGCCTTCTCCTCAC
TGCCCTTTAGGCTCCCAGGGCCAGAGGAGCCAGGGACTATTTTCTGCACCAGCCCCCAGGGCTGCCACCCCTGTTGTGTCTTTTTTTCAG
ACTCACAGTGGAGCTTCCAGGACCCAGAATAAAGCCAATGATTTACTTGTTTCA

>42949_42949_9_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718429_ENST00000416589_length(amino acids)=276AA_BP=49
LQRPGKMVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKVPPDKCRCAVGSILSEGEESPSPELIDLYQKFGFKVFSFPA
PSHVVTATFPYTTILSIWLATRRVHPALDTYIKERKLCAYPRLEIYQEDQIHFMCPLARQGDFYVPEMKETEWKWRGLVEAIDTQVDGTG
ADTMSDTSSVSLEVSPGSRETSAATLSPGASSRGWDDGDTRSEHSYSESGASGSSFEELDLEGEGPLGESRLDPGTEPLGTTKWLWEPTA
PEKGKE

--------------------------------------------------------------
>42949_42949_10_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718429_ENST00000457573_length(transcript)=1139nt_BP=149nt
AGTTGCAGCGGCCGGGGAAGATGGTGGAGGACGGCGCGGAGGAGCTGGAGGATCTGGTGCACTTCTCCGTGTCTGAGTTGCCTAGTCGCG
GCTACGGCGTCATGGAGGAGATCCGGCGGCAGGGCAAGCTGTGCGACGTGACCCTCAAGGTGCCCCCTGATAAGTGCCGATGTGCCGTGG
GCAGCATCCTGAGTGAAGGTGAGGAATCGCCCTCCCCTGAGCTCATCGACCTCTACCAGAAATTTGGCTTCAAGGTGTTCTCCTTCCCGG
CACCCAGCCATGTGGTGACAGCCACCTTCCCCTACACCACCATTCTGTCCATCTGGCTGGCTACCCGCCGTGTCCATCCTGCCTTGGACA
CCTACATCAAGGAGCGGAAGCTGTGTGCCTATCCTCGGCTGGAGATCTACCAGGAAGACCAGATCCATTTCATGTGCCCACTGGCACGGC
AGGGAGACTTCTATGTGCCTGAGATGAAGGAGACAGAGTGGAAATGGCGGGGGCTTGTGGAGGCCATTGACACCCAGGTGGATGGCACAG
GAGCTGACACAATGAGTGACACGAGTTCTGTAAGCTTGGAAGTGAGCCCTGGCAGCCGGGAGACTTCAGCTGCCACACTGTCACCTGGGG
CGAGCAGCCGTGGCTGGGATGACGGTGACACCCGCAGCGAGCACAGCTACAGCGAGTCAGGTGCCAGCGGCTCCTCTTTTGAGGAGCTGG
ACTTGGAGGGCGAGGGGCCCTTAGGGGAGTCACGGCTGGACCCTGGGACTGAGCCCCTGGGGACTACCAAGTGGCTCTGGGAGCCCACTG
CCCCTGAGAAGGGCAAGGAGTAACCCATGGCCTGCACCCTCCTGCAGTGCAGTTGCTGAGGAACTGAGCAGACTCTCCAGCAGACTCTCC
AGCCCTCTTCCTCCTTCCTCTGGGGGAGGAGGGGTTCCTGAGGGACCTGACTTCCCCTGCTCCAGGCCTCTTGCTAAGCCTTCTCCTCAC
TGCCCTTTAGGCTCCCAGGGCCAGAGGAGCCAGGGACTATTTTCTGCACCAGCCCCCAGGGCTGCCACCCCTGTTGTGTCTTTTTTTCAG
ACTCACAGTGGAGCTTCCAGGACCCAGAATAAAGCCAATGATTTACTTGTTTCACCTGG

>42949_42949_10_KLHL18-TEX264_KLHL18_chr3_47324584_ENST00000232766_TEX264_chr3_51718429_ENST00000457573_length(amino acids)=276AA_BP=49
LQRPGKMVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKVPPDKCRCAVGSILSEGEESPSPELIDLYQKFGFKVFSFPA
PSHVVTATFPYTTILSIWLATRRVHPALDTYIKERKLCAYPRLEIYQEDQIHFMCPLARQGDFYVPEMKETEWKWRGLVEAIDTQVDGTG
ADTMSDTSSVSLEVSPGSRETSAATLSPGASSRGWDDGDTRSEHSYSESGASGSSFEELDLEGEGPLGESRLDPGTEPLGTTKWLWEPTA
PEKGKE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for KLHL18-TEX264


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for KLHL18-TEX264


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for KLHL18-TEX264


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource