![]() |
||||||
|
![]() | Fusion Gene Summary |
![]() | Fusion Gene ORF analysis |
![]() | Fusion Genomic Features |
![]() | Fusion Protein Features |
![]() | Fusion Gene Sequence |
![]() | Fusion Gene PPI analysis |
![]() | Related Drugs |
![]() | Related Diseases |
Fusion gene:FN1-ABCA12 (FusionGDB2 ID:HG2335TG26154) |
Fusion Gene Summary for FN1-ABCA12 |
![]() |
Fusion gene information | Fusion gene name: FN1-ABCA12 | Fusion gene ID: hg2335tg26154 | Hgene | Tgene | Gene symbol | FN1 | ABCA12 | Gene ID | 2335 | 26154 |
Gene name | fibronectin 1 | ATP binding cassette subfamily A member 12 | |
Synonyms | CIG|ED-B|FINC|FN|FNZ|GFND|GFND2|LETS|MSF|SMDCF | ARCI4A|ARCI4B|ICR2B|LI2 | |
Cytomap | ('FN1')('ABCA12') 2q35 | 2q35 | |
Type of gene | protein-coding | protein-coding | |
Description | fibronectincold-insoluble globulinepididymis secretory sperm binding proteinmigration-stimulating factor | ATP-binding cassette sub-family A member 12ATP-binding cassette transporter 12ATP-binding cassette, sub-family A (ABC1), member 12 | |
Modification date | 20200329 | 20200313 | |
UniProtAcc | P02751 | . | |
Ensembl transtripts involved in fusion gene | ENST00000323926, ENST00000336916, ENST00000345488, ENST00000346544, ENST00000354785, ENST00000356005, ENST00000357009, ENST00000357867, ENST00000359671, ENST00000421182, ENST00000432072, ENST00000443816, ENST00000446046, ENST00000426059, ENST00000490833, | ||
Fusion gene scores | * DoF score | 47 X 49 X 13=29939 | 5 X 6 X 4=120 |
# samples | 48 | 5 | |
** MAII score | log2(48/29939*10)=-5.96284781832542 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/120*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: FN1 [Title/Abstract] AND ABCA12 [Title/Abstract] AND fusion [Title/Abstract] | ||
Most frequent breakpoint | FN1(216259250)-ABCA12(215945571), # samples:1 FN1(216259250)-ABCA12(215940339), # samples:1 | ||
Anticipated loss of major functional domain due to fusion event. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
![]() |
Partner | Gene | GO ID | GO term | PubMed ID |
Hgene | FN1 | GO:0001932 | regulation of protein phosphorylation | 11792823 |
Hgene | FN1 | GO:0008284 | positive regulation of cell proliferation | 25834989 |
Hgene | FN1 | GO:0010628 | positive regulation of gene expression | 25834989 |
Hgene | FN1 | GO:0018149 | peptide cross-linking | 3997886 |
Hgene | FN1 | GO:0034446 | substrate adhesion-dependent cell spreading | 16236823 |
Hgene | FN1 | GO:0035987 | endodermal cell differentiation | 23154389 |
Hgene | FN1 | GO:0048146 | positive regulation of fibroblast proliferation | 25834989 |
Hgene | FN1 | GO:0051702 | interaction with symbiont | 12167537|12421310|19429745 |
Hgene | FN1 | GO:0070372 | regulation of ERK1 and ERK2 cascade | 11792823 |
Hgene | FN1 | GO:1901166 | neural crest cell migration involved in autonomic nervous system development | 26571399 |
Hgene | FN1 | GO:1904237 | positive regulation of substrate-dependent cell migration, cell attachment to substrate | 25834989 |
Hgene | FN1 | GO:2001202 | negative regulation of transforming growth factor-beta secretion | 25834989 |
Tgene | ABCA12 | GO:0006869 | lipid transport | 16007253 |
Tgene | ABCA12 | GO:0010875 | positive regulation of cholesterol efflux | 23931754 |
Tgene | ABCA12 | GO:0072659 | protein localization to plasma membrane | 23931754 |
![]() * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChimerDB4 | LUAD | TCGA-86-8669-01A | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
ChimerDB4 | LUAD | TCGA-86-8669-01A | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
Top |
Fusion Gene ORF analysis for FN1-ABCA12 |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
5CDS-intron | ENST00000323926 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000323926 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000323926 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000323926 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000323926 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000323926 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000336916 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000336916 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000336916 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000336916 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000336916 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000336916 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000345488 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000345488 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000345488 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000345488 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000345488 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000345488 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000346544 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000346544 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000346544 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000346544 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000346544 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000346544 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000354785 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000354785 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000354785 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000354785 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000354785 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000354785 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000356005 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000356005 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000356005 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000356005 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000356005 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000356005 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000357009 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000357009 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000357009 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000357009 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000357009 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000357009 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000357867 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000357867 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000357867 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000357867 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000357867 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000357867 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000359671 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000359671 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000359671 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000359671 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000359671 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000359671 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000421182 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000421182 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000421182 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000421182 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000421182 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000421182 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000432072 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000432072 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000432072 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000432072 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000432072 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000432072 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000443816 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000443816 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000443816 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000443816 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000443816 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000443816 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000446046 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000446046 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000446046 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000446046 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
5CDS-intron | ENST00000446046 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
5CDS-intron | ENST00000446046 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
intron-intron | ENST00000426059 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
intron-intron | ENST00000426059 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
intron-intron | ENST00000426059 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
intron-intron | ENST00000426059 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
intron-intron | ENST00000426059 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
intron-intron | ENST00000426059 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
intron-intron | ENST00000490833 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
intron-intron | ENST00000490833 | ENST00000272895 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
intron-intron | ENST00000490833 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
intron-intron | ENST00000490833 | ENST00000389661 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
intron-intron | ENST00000490833 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215940339 | - |
intron-intron | ENST00000490833 | ENST00000412081 | FN1 | chr2 | 216259250 | - | ABCA12 | chr2 | 215945571 | - |
![]() |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
![]() |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
Top |
Fusion Genomic Features for FN1-ABCA12 |
![]() |
Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
Top |
Fusion Protein Features for FN1-ABCA12 |
![]() Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:216259250/:215945571) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
![]() |
![]() |
Hgene | Tgene |
FN1 | . |
FUNCTION: Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin (PubMed:3024962, PubMed:3900070, PubMed:3593230, PubMed:7989369). Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape (PubMed:3024962, PubMed:3900070, PubMed:3593230, PubMed:7989369). Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization (By similarity). Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). Acts as a ligand for the LILRB4 receptor, inhibiting FCGR1A/CD64-mediated monocyte activation (PubMed:34089617). {ECO:0000250|UniProtKB:P11276, ECO:0000269|PubMed:3024962, ECO:0000269|PubMed:34089617, ECO:0000269|PubMed:3593230, ECO:0000269|PubMed:3900070, ECO:0000269|PubMed:7989369}.; FUNCTION: [Anastellin]: Binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling. {ECO:0000269|PubMed:11209058, ECO:0000269|PubMed:15665290, ECO:0000269|PubMed:19379667, ECO:0000269|PubMed:8114919}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
Fusion Gene Sequence for FN1-ABCA12 |
![]() |
Top |
Fusion Gene PPI Analysis for FN1-ABCA12 |
![]() |
![]() |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Related Drugs for FN1-ABCA12 |
![]() (DrugBank Version 5.1.8 2021-05-08) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Hgene | FN1 | P02751 | DB08888 | Ocriplasmin | Cleavage | Biotech | Approved |
Hgene | FN1 | P02751 | DB08888 | Ocriplasmin | Cleavage | Biotech | Approved |
Hgene | FN1 | P02751 | DB14548 | Zinc sulfate, unspecified form | Ligand|Modulator | Small molecule | Approved|Experimental |
Hgene | FN1 | P02751 | DB14548 | Zinc sulfate, unspecified form | Ligand|Modulator | Small molecule | Approved|Experimental |
Hgene | FN1 | P02751 | DB01593 | Zinc | Small molecule | Approved|Investigational | |
Hgene | FN1 | P02751 | DB01593 | Zinc | Small molecule | Approved|Investigational | |
Hgene | FN1 | P02751 | DB14487 | Zinc acetate | Small molecule | Approved|Investigational | |
Hgene | FN1 | P02751 | DB14487 | Zinc acetate | Small molecule | Approved|Investigational | |
Hgene | FN1 | P02751 | DB14533 | Zinc chloride | Ligand|Modulator | Small molecule | Approved|Investigational |
Hgene | FN1 | P02751 | DB14533 | Zinc chloride | Ligand|Modulator | Small molecule | Approved|Investigational |
Top |
Related Diseases for FN1-ABCA12 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | FN1 | C0020538 | Hypertensive disease | 2 | CTD_human |
Hgene | FN1 | C0432221 | Spondylometaphyseal dysplasia, 'corner fracture' type | 2 | GENOMICS_ENGLAND;ORPHANET;UNIPROT |
Hgene | FN1 | C0000786 | Spontaneous abortion | 1 | CTD_human |
Hgene | FN1 | C0000822 | Abortion, Tubal | 1 | CTD_human |
Hgene | FN1 | C0003504 | Aortic Valve Insufficiency | 1 | CTD_human |
Hgene | FN1 | C0006142 | Malignant neoplasm of breast | 1 | CTD_human;UNIPROT |
Hgene | FN1 | C0007097 | Carcinoma | 1 | CTD_human |
Hgene | FN1 | C0007621 | Neoplastic Cell Transformation | 1 | CTD_human |
Hgene | FN1 | C0010346 | Crohn Disease | 1 | CTD_human |
Hgene | FN1 | C0011849 | Diabetes Mellitus | 1 | CTD_human |
Hgene | FN1 | C0011881 | Diabetic Nephropathy | 1 | CTD_human |
Hgene | FN1 | C0017636 | Glioblastoma | 1 | CTD_human |
Hgene | FN1 | C0017667 | Nodular glomerulosclerosis | 1 | CTD_human |
Hgene | FN1 | C0017668 | Focal glomerulosclerosis | 1 | CTD_human |
Hgene | FN1 | C0024667 | Animal Mammary Neoplasms | 1 | CTD_human |
Hgene | FN1 | C0024668 | Mammary Neoplasms, Experimental | 1 | CTD_human |
Hgene | FN1 | C0027626 | Neoplasm Invasiveness | 1 | CTD_human |
Hgene | FN1 | C0034069 | Pulmonary Fibrosis | 1 | CTD_human |
Hgene | FN1 | C0041956 | Ureteral obstruction | 1 | CTD_human |
Hgene | FN1 | C0085762 | Alcohol abuse | 1 | PSYGENET |
Hgene | FN1 | C0086432 | Hyalinosis, Segmental Glomerular | 1 | CTD_human |
Hgene | FN1 | C0149721 | Left Ventricular Hypertrophy | 1 | CTD_human |
Hgene | FN1 | C0156147 | Crohn's disease of large bowel | 1 | CTD_human |
Hgene | FN1 | C0205696 | Anaplastic carcinoma | 1 | CTD_human |
Hgene | FN1 | C0205697 | Carcinoma, Spindle-Cell | 1 | CTD_human |
Hgene | FN1 | C0205698 | Undifferentiated carcinoma | 1 | CTD_human |
Hgene | FN1 | C0205699 | Carcinomatosis | 1 | CTD_human |
Hgene | FN1 | C0267380 | Crohn's disease of the ileum | 1 | CTD_human |
Hgene | FN1 | C0334588 | Giant Cell Glioblastoma | 1 | CTD_human |
Hgene | FN1 | C0345967 | Malignant mesothelioma | 1 | CTD_human |
Hgene | FN1 | C0678202 | Regional enteritis | 1 | CTD_human |
Hgene | FN1 | C0678222 | Breast Carcinoma | 1 | CTD_human |
Hgene | FN1 | C0949272 | IIeocolitis | 1 | CTD_human |
Hgene | FN1 | C1257925 | Mammary Carcinoma, Animal | 1 | CTD_human |
Hgene | FN1 | C1257931 | Mammary Neoplasms, Human | 1 | CTD_human |
Hgene | FN1 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
Hgene | FN1 | C1621958 | Glioblastoma Multiforme | 1 | CTD_human |
Hgene | FN1 | C1866075 | GLOMERULOPATHY WITH FIBRONECTIN DEPOSITS 2 (disorder) | 1 | CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT |
Hgene | FN1 | C3830362 | Early Pregnancy Loss | 1 | CTD_human |
Hgene | FN1 | C3888104 | Glomerulopathy with fibronectin deposits | 1 | CTD_human;ORPHANET |
Hgene | FN1 | C4552766 | Miscarriage | 1 | CTD_human |
Hgene | FN1 | C4704874 | Mammary Carcinoma, Human | 1 | CTD_human |
Hgene | FN1 | C4721507 | Alveolitis, Fibrosing | 1 | CTD_human |
Tgene | C0079154 | Congenital Nonbullous Ichthyosiform Erythroderma | 5 | CTD_human;GENOMICS_ENGLAND;ORPHANET | |
Tgene | C1832550 | Lamellar ichthyosis, type 2 | 5 | CTD_human;GENOMICS_ENGLAND;UNIPROT | |
Tgene | C0598226 | Harlequin type ichthyosis | 3 | CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT | |
Tgene | C0239849 | Harlequin Fetus | 2 | CTD_human;GENOMICS_ENGLAND;ORPHANET | |
Tgene | C0009402 | Colorectal Carcinoma | 1 | CTD_human | |
Tgene | C0009404 | Colorectal Neoplasms | 1 | CTD_human | |
Tgene | C0020758 | Congenital ichthyosis | 1 | CTD_human | |
Tgene | C3536797 | Ichthyosis Congenita II | 1 | CTD_human | |
Tgene | C3543867 | Collodion Fetus | 1 | CTD_human | |
Tgene | C4551630 | Ichthyosis Congenita I | 1 | CTD_human |