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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Diseases

Fusion gene:ARHGEF18-MAPKAP1 (FusionGDB2 ID:HG23370TG79109)

Fusion Gene Summary for ARHGEF18-MAPKAP1

check button Fusion gene summary
Fusion gene informationFusion gene name: ARHGEF18-MAPKAP1
Fusion gene ID: hg23370tg79109
HgeneTgene
Gene symbol

ARHGEF18

MAPKAP1

Gene ID

23370

79109

Gene nameRho/Rac guanine nucleotide exchange factor 18MAPK associated protein 1
SynonymsP114-RhoGEF|RP78|SA-RhoGEF|p114RhoGEFJC310|MIP1|SIN1|SIN1b|SIN1g
Cytomap('ARHGEF18')('MAPKAP1')

19p13.2

9q33.3

Type of geneprotein-codingprotein-coding
Descriptionrho guanine nucleotide exchange factor 18114 kDa Rho-specific guanine nucleotide exchange factorRho-specific guanine nucleotide exchange factor p114Rho/Rac guanine nucleotide exchange factor (GEF) 18septin-associated RhoGEFtarget of rapamycin complex 2 subunit MAPKAP1MEKK2-interacting protein 1SAPK-interacting protein 1TORC2 subunit MAPKAP1mSIN1mitogen-activated protein kinase 2-associated protein 1mitogen-activated protein kinase associated protein 1ras inhibitor MG
Modification date2020032020200329
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000319670, ENST00000359920, 
Fusion gene scores* DoF score14 X 8 X 12=134412 X 10 X 10=1200
# samples 1613
** MAII scorelog2(16/1344*10)=-3.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/1200*10)=-3.20645087746743
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ARHGEF18 [Title/Abstract] AND MAPKAP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointARHGEF18(7506938)-MAPKAP1(128230388), # samples:3
Anticipated loss of major functional domain due to fusion event.ARHGEF18-MAPKAP1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARHGEF18-MAPKAP1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARHGEF18-MAPKAP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ARHGEF18-MAPKAP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneARHGEF18

GO:0007264

small GTPase mediated signal transduction

14512443

HgeneARHGEF18

GO:0008360

regulation of cell shape

14512443

HgeneARHGEF18

GO:0030036

actin cytoskeleton organization

14512443


check buttonFusion gene breakpoints across ARHGEF18 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across MAPKAP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4COADTCGA-AD-6901-01AARHGEF18chr19

7506938

-MAPKAP1chr9

128230388

-
ChimerDB4COADTCGA-AD-6901-01AARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
ChimerDB4COADTCGA-AD-6901-01AARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
ChimerDB4COADTCGA-AD-6901ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-


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Fusion Gene ORF analysis for ARHGEF18-MAPKAP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000319670ENST00000483937ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
5CDS-5UTRENST00000319670ENST00000483937ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
5CDS-5UTRENST00000359920ENST00000483937ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
5CDS-5UTRENST00000359920ENST00000483937ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
5CDS-intronENST00000319670ENST00000265960ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
5CDS-intronENST00000319670ENST00000350766ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
5CDS-intronENST00000319670ENST00000373497ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
5CDS-intronENST00000319670ENST00000373498ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
5CDS-intronENST00000319670ENST00000373503ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
5CDS-intronENST00000319670ENST00000373511ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
5CDS-intronENST00000319670ENST00000394060ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
5CDS-intronENST00000319670ENST00000394060ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
5CDS-intronENST00000319670ENST00000394063ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
5CDS-intronENST00000359920ENST00000265960ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
5CDS-intronENST00000359920ENST00000350766ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
5CDS-intronENST00000359920ENST00000373497ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
5CDS-intronENST00000359920ENST00000373498ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
5CDS-intronENST00000359920ENST00000373503ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
5CDS-intronENST00000359920ENST00000373511ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
5CDS-intronENST00000359920ENST00000394060ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
5CDS-intronENST00000359920ENST00000394060ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
5CDS-intronENST00000359920ENST00000394063ARHGEF18chr19

7506938

+MAPKAP1chr9

128233694

-
In-frameENST00000319670ENST00000265960ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
In-frameENST00000319670ENST00000350766ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
In-frameENST00000319670ENST00000373497ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
In-frameENST00000319670ENST00000373498ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
In-frameENST00000319670ENST00000373503ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
In-frameENST00000319670ENST00000373511ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
In-frameENST00000319670ENST00000394063ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
In-frameENST00000359920ENST00000265960ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
In-frameENST00000359920ENST00000350766ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
In-frameENST00000359920ENST00000373497ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
In-frameENST00000359920ENST00000373498ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
In-frameENST00000359920ENST00000373503ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
In-frameENST00000359920ENST00000373511ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-
In-frameENST00000359920ENST00000394063ARHGEF18chr19

7506938

+MAPKAP1chr9

128230388

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000319670ARHGEF18chr197506938+ENST00000373511MAPKAP1chr9128230388-238452880889269
ENST00000319670ARHGEF18chr197506938+ENST00000373498MAPKAP1chr9128230388-238352880889269
ENST00000319670ARHGEF18chr197506938+ENST00000350766MAPKAP1chr9128230388-238352880889269
ENST00000319670ARHGEF18chr197506938+ENST00000373503MAPKAP1chr9128230388-238352880889269
ENST00000319670ARHGEF18chr197506938+ENST00000394063MAPKAP1chr9128230388-238352880889269
ENST00000319670ARHGEF18chr197506938+ENST00000265960MAPKAP1chr9128230388-238352880889269
ENST00000319670ARHGEF18chr197506938+ENST00000373497MAPKAP1chr9128230388-124452880889269
ENST00000359920ARHGEF18chr197506938+ENST00000373511MAPKAP1chr9128230388-290510492531410385
ENST00000359920ARHGEF18chr197506938+ENST00000373498MAPKAP1chr9128230388-290410492531410385
ENST00000359920ARHGEF18chr197506938+ENST00000350766MAPKAP1chr9128230388-290410492531410385
ENST00000359920ARHGEF18chr197506938+ENST00000373503MAPKAP1chr9128230388-290410492531410385
ENST00000359920ARHGEF18chr197506938+ENST00000394063MAPKAP1chr9128230388-290410492531410385
ENST00000359920ARHGEF18chr197506938+ENST00000265960MAPKAP1chr9128230388-290410492531410385
ENST00000359920ARHGEF18chr197506938+ENST00000373497MAPKAP1chr9128230388-176510492531410385

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000319670ENST00000373511ARHGEF18chr197506938+MAPKAP1chr9128230388-0.0037596750.9962404
ENST00000319670ENST00000373498ARHGEF18chr197506938+MAPKAP1chr9128230388-0.0037385960.9962614
ENST00000319670ENST00000350766ARHGEF18chr197506938+MAPKAP1chr9128230388-0.0037385960.9962614
ENST00000319670ENST00000373503ARHGEF18chr197506938+MAPKAP1chr9128230388-0.0037385960.9962614
ENST00000319670ENST00000394063ARHGEF18chr197506938+MAPKAP1chr9128230388-0.0037385960.9962614
ENST00000319670ENST00000265960ARHGEF18chr197506938+MAPKAP1chr9128230388-0.0037385960.9962614
ENST00000319670ENST00000373497ARHGEF18chr197506938+MAPKAP1chr9128230388-0.0071437090.99285626
ENST00000359920ENST00000373511ARHGEF18chr197506938+MAPKAP1chr9128230388-0.0019159710.99808407
ENST00000359920ENST00000373498ARHGEF18chr197506938+MAPKAP1chr9128230388-0.0019255720.9980744
ENST00000359920ENST00000350766ARHGEF18chr197506938+MAPKAP1chr9128230388-0.0019255720.9980744
ENST00000359920ENST00000373503ARHGEF18chr197506938+MAPKAP1chr9128230388-0.0019255720.9980744
ENST00000359920ENST00000394063ARHGEF18chr197506938+MAPKAP1chr9128230388-0.0019255720.9980744
ENST00000359920ENST00000265960ARHGEF18chr197506938+MAPKAP1chr9128230388-0.0019255720.9980744
ENST00000359920ENST00000373497ARHGEF18chr197506938+MAPKAP1chr9128230388-0.0092328080.9907672

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Fusion Genomic Features for ARHGEF18-MAPKAP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ARHGEF18-MAPKAP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:7506938/chr9:128230388)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARHGEF18chr19:7506938chr9:128230388ENST00000319670+4211038_11481071618.0Coiled coilOntology_term=ECO:0000255
HgeneARHGEF18chr19:7506938chr9:128230388ENST00000359920+3201038_11482651556.0Coiled coilOntology_term=ECO:0000255
HgeneARHGEF18chr19:7506938chr9:128230388ENST00000319670+4211042_11421071618.0Compositional biasArg-rich
HgeneARHGEF18chr19:7506938chr9:128230388ENST00000319670+4211292_13461071618.0Compositional biasPro-rich
HgeneARHGEF18chr19:7506938chr9:128230388ENST00000359920+3201042_11422651556.0Compositional biasArg-rich
HgeneARHGEF18chr19:7506938chr9:128230388ENST00000359920+3201292_13462651556.0Compositional biasPro-rich
HgeneARHGEF18chr19:7506938chr9:128230388ENST00000319670+421447_6441071618.0DomainDH
HgeneARHGEF18chr19:7506938chr9:128230388ENST00000319670+421684_7861071618.0DomainPH
HgeneARHGEF18chr19:7506938chr9:128230388ENST00000359920+320447_6442651556.0DomainDH
HgeneARHGEF18chr19:7506938chr9:128230388ENST00000359920+320684_7862651556.0DomainPH
HgeneARHGEF18chr19:7506938chr9:128230388ENST00000319670+421310_3341071618.0Zinc fingerC2H2-type%3B degenerate
HgeneARHGEF18chr19:7506938chr9:128230388ENST00000359920+320310_3342651556.0Zinc fingerC2H2-type%3B degenerate


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Fusion Gene Sequence for ARHGEF18-MAPKAP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>6240_6240_1_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000319670_MAPKAP1_chr9_128230388_ENST00000265960_length(transcript)=2383nt_BP=528nt
CTCGCGCGGCTTCCCGCTTCCGGCTCCCAGCTGCTAGCTACTGTGGATCTGGGGGGGCCGGACGGAGGCATCGGAGGCGGCTGCGAGAGT
GGCAGAGGAGCTGGCGGAGAGCGGCCTGCGGGCGATCGGGCCGAGCCTCGCTCAAGGAGCACCCCCGGGGCACCCTCCTGTCCGATGGCA
GCCCGGCCCTGTCCAGGAATGTCGGTATGACGGTCTCTCAGAAAGGGGGTCCCCAGCCAACACCGAGCCCGGCTGGCCCTGGGACGCAAC
TCGGACCAATCACAGGAGAGATGGATGAAGCCGATTCTGCGTTTTTAAAATTTAAGCAGACAGCTGATGACTCTCTGTCCCTTACATCTC
CAAACACCGAGTCCATTTTTGTAGAAGATCCCTACACCGCCTCGCTGAGGAGTGAGATTGAGTCAGACGGCCACGAGTTTGAAGCTGAGT
CCTGGAGCCTCGCCGTGGATGCAGCCTACGCCAAGAAGCAAAAGAGGGAGGTGGTGAAAAGACAAGATGTCCTTTATGGTATCTCTGGAG
ACAAAGTAGAGATAGACCCTGTTACGAATCAGAAAGCCAGCACTAAGTTTTGGATTAAGCAGAAACCCATCTCAATCGATTCCGACCTGC
TCTGTGCCTGTGACCTTGCTGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCACGTATCTAAGCAATCACGACTATAAACACCTCT
ACTTTGAATCGGACGCTGCTACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGAGCTAGCACTGCCCGGGCTGACT
ACTTTGCTCAAAAACAAAGAAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGTGACACTGGCCTC
CAGCCTCAATCTGTTCCGTAGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGAGG
CCAGCCCCTGGCTCACTGGCACAGGGCAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATG
GGACGGAAGTCTGCTTGGCAGTGGCTTTGATAAGCGATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTT
CAATGCCTGCCACCCTGCCCGAGGATGTACAGAGCCGTGCCCACACATTTCCTTGCAACTTGATCAAATTTCTTAAAGCAAACAACAAAA
ATGTACATTTCTGTTTTTCCTTTTAATAAACAGGTGTACTCTTTATCATGGTTGGTATGATGGACCATTCTTTGGGGCGGAGGATTGATT
ATGTTACTCTCTTTAAAATCTGTTCCCATATTGAACAGGCAGATTGGAAAAGCTATGGTTCGATTTCTCAGAAGAAATGTTTAGGTCTTA
GTCAATAGTTTTAACTATGCCATTTGTTTAAATGAGTGCATTTGCTTCGAGGGTAGTGTCTTACTAAAAGTTAGGAACAGAGACCTAGTG
GTGTGTCCAAGGCCGTGTCACTTTCCCCTTCAGCACACCCCAGCTTCTGACCTCAGAGCCCAGGAGCTGCGTGGACAGTGTGGGGTGCCA
GGAGGAGGGGCGGTGGCTGGTCCTCAGGCACGCTGCACTCCCAGCCAGACATGGTCTTTCCGTTTCTTAAGTAGCAAGTGTAGGTTTCAG
CTGGCAGTTCCACCTGCATGTTCTCTGCTTCGCTGCCTTGGAAGGGGCCACATTCCCCATTCCTCTTCTCCTTACAGCGCCTGCCTCCTT
TTTCAAGCAGGCGGAAAGCTGCTGTTTCTCACGTTTCAGGGAGAGGGGTGAGCGGAGGGAGACCTGTGTCCGTGCCGTCCGGCTCCCTGG
GTGGGAACAGGCAAGGGATCAGATGCCCCTGACACCACGCCTCTGGCCACACCAGATGCCTCTGCAGTCCTCGACAGCCTCTTCAGTGTC
CCTCCTGCGGTGATGTCCTTACTGTCCCCAGCCAGGGCCGGGGACCGGTGTTTCACTGAGGACCTGCATTAGAAACATTTTTTAAATTGT
TGTACAGGAAGAGATGTGTCTAAAACAGCATCTTAAAGCTGAGTGTATTTCTTTGCACAAGGGGTCATGCTGATGAATTCTTCTTTCATT
CTGATCTTTGTTCAGCCAACAGGAGCGTCCTTTTCTAATGTCTTCCATTCCTACCCCCCACCCAAAAACAAAAGAAATATTTGTAGCTTG
CTATCTGTATTTGAATTTTTAGCAATTTTATATTTAGATACTTTGAAAAATGTAAATGACTAATTTGGTCATTAAATCTTGTGACATATT

>6240_6240_1_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000319670_MAPKAP1_chr9_128230388_ENST00000265960_length(amino acids)=269AA_BP=147
MREWQRSWRRAACGRSGRASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPAGPGTQLGPITGEMDEADSAFLKFKQTADDSLS
LTSPNTESIFVEDPYTASLRSEIESDGHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYGISGDKVEIDPVTNQKASTKFWIKQKPISID

--------------------------------------------------------------
>6240_6240_2_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000319670_MAPKAP1_chr9_128230388_ENST00000350766_length(transcript)=2383nt_BP=528nt
CTCGCGCGGCTTCCCGCTTCCGGCTCCCAGCTGCTAGCTACTGTGGATCTGGGGGGGCCGGACGGAGGCATCGGAGGCGGCTGCGAGAGT
GGCAGAGGAGCTGGCGGAGAGCGGCCTGCGGGCGATCGGGCCGAGCCTCGCTCAAGGAGCACCCCCGGGGCACCCTCCTGTCCGATGGCA
GCCCGGCCCTGTCCAGGAATGTCGGTATGACGGTCTCTCAGAAAGGGGGTCCCCAGCCAACACCGAGCCCGGCTGGCCCTGGGACGCAAC
TCGGACCAATCACAGGAGAGATGGATGAAGCCGATTCTGCGTTTTTAAAATTTAAGCAGACAGCTGATGACTCTCTGTCCCTTACATCTC
CAAACACCGAGTCCATTTTTGTAGAAGATCCCTACACCGCCTCGCTGAGGAGTGAGATTGAGTCAGACGGCCACGAGTTTGAAGCTGAGT
CCTGGAGCCTCGCCGTGGATGCAGCCTACGCCAAGAAGCAAAAGAGGGAGGTGGTGAAAAGACAAGATGTCCTTTATGGTATCTCTGGAG
ACAAAGTAGAGATAGACCCTGTTACGAATCAGAAAGCCAGCACTAAGTTTTGGATTAAGCAGAAACCCATCTCAATCGATTCCGACCTGC
TCTGTGCCTGTGACCTTGCTGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCACGTATCTAAGCAATCACGACTATAAACACCTCT
ACTTTGAATCGGACGCTGCTACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGAGCTAGCACTGCCCGGGCTGACT
ACTTTGCTCAAAAACAAAGAAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGTGACACTGGCCTC
CAGCCTCAATCTGTTCCGTAGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGAGG
CCAGCCCCTGGCTCACTGGCACAGGGCAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATG
GGACGGAAGTCTGCTTGGCAGTGGCTTTGATAAGCGATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTT
CAATGCCTGCCACCCTGCCCGAGGATGTACAGAGCCGTGCCCACACATTTCCTTGCAACTTGATCAAATTTCTTAAAGCAAACAACAAAA
ATGTACATTTCTGTTTTTCCTTTTAATAAACAGGTGTACTCTTTATCATGGTTGGTATGATGGACCATTCTTTGGGGCGGAGGATTGATT
ATGTTACTCTCTTTAAAATCTGTTCCCATATTGAACAGGCAGATTGGAAAAGCTATGGTTCGATTTCTCAGAAGAAATGTTTAGGTCTTA
GTCAATAGTTTTAACTATGCCATTTGTTTAAATGAGTGCATTTGCTTCGAGGGTAGTGTCTTACTAAAAGTTAGGAACAGAGACCTAGTG
GTGTGTCCAAGGCCGTGTCACTTTCCCCTTCAGCACACCCCAGCTTCTGACCTCAGAGCCCAGGAGCTGCGTGGACAGTGTGGGGTGCCA
GGAGGAGGGGCGGTGGCTGGTCCTCAGGCACGCTGCACTCCCAGCCAGACATGGTCTTTCCGTTTCTTAAGTAGCAAGTGTAGGTTTCAG
CTGGCAGTTCCACCTGCATGTTCTCTGCTTCGCTGCCTTGGAAGGGGCCACATTCCCCATTCCTCTTCTCCTTACAGCGCCTGCCTCCTT
TTTCAAGCAGGCGGAAAGCTGCTGTTTCTCACGTTTCAGGGAGAGGGGTGAGCGGAGGGAGACCTGTGTCCGTGCCGTCCGGCTCCCTGG
GTGGGAACAGGCAAGGGATCAGATGCCCCTGACACCACGCCTCTGGCCACACCAGATGCCTCTGCAGTCCTCGACAGCCTCTTCAGTGTC
CCTCCTGCGGTGATGTCCTTACTGTCCCCAGCCAGGGCCGGGGACCGGTGTTTCACTGAGGACCTGCATTAGAAACATTTTTTAAATTGT
TGTACAGGAAGAGATGTGTCTAAAACAGCATCTTAAAGCTGAGTGTATTTCTTTGCACAAGGGGTCATGCTGATGAATTCTTCTTTCATT
CTGATCTTTGTTCAGCCAACAGGAGCGTCCTTTTCTAATGTCTTCCATTCCTACCCCCCACCCAAAAACAAAAGAAATATTTGTAGCTTG
CTATCTGTATTTGAATTTTTAGCAATTTTATATTTAGATACTTTGAAAAATGTAAATGACTAATTTGGTCATTAAATCTTGTGACATATT

>6240_6240_2_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000319670_MAPKAP1_chr9_128230388_ENST00000350766_length(amino acids)=269AA_BP=147
MREWQRSWRRAACGRSGRASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPAGPGTQLGPITGEMDEADSAFLKFKQTADDSLS
LTSPNTESIFVEDPYTASLRSEIESDGHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYGISGDKVEIDPVTNQKASTKFWIKQKPISID

--------------------------------------------------------------
>6240_6240_3_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000319670_MAPKAP1_chr9_128230388_ENST00000373497_length(transcript)=1244nt_BP=528nt
CTCGCGCGGCTTCCCGCTTCCGGCTCCCAGCTGCTAGCTACTGTGGATCTGGGGGGGCCGGACGGAGGCATCGGAGGCGGCTGCGAGAGT
GGCAGAGGAGCTGGCGGAGAGCGGCCTGCGGGCGATCGGGCCGAGCCTCGCTCAAGGAGCACCCCCGGGGCACCCTCCTGTCCGATGGCA
GCCCGGCCCTGTCCAGGAATGTCGGTATGACGGTCTCTCAGAAAGGGGGTCCCCAGCCAACACCGAGCCCGGCTGGCCCTGGGACGCAAC
TCGGACCAATCACAGGAGAGATGGATGAAGCCGATTCTGCGTTTTTAAAATTTAAGCAGACAGCTGATGACTCTCTGTCCCTTACATCTC
CAAACACCGAGTCCATTTTTGTAGAAGATCCCTACACCGCCTCGCTGAGGAGTGAGATTGAGTCAGACGGCCACGAGTTTGAAGCTGAGT
CCTGGAGCCTCGCCGTGGATGCAGCCTACGCCAAGAAGCAAAAGAGGGAGGTGGTGAAAAGACAAGATGTCCTTTATGGTATCTCTGGAG
ACAAAGTAGAGATAGACCCTGTTACGAATCAGAAAGCCAGCACTAAGTTTTGGATTAAGCAGAAACCCATCTCAATCGATTCCGACCTGC
TCTGTGCCTGTGACCTTGCTGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCACGTATCTAAGCAATCACGACTATAAACACCTCT
ACTTTGAATCGGACGCTGCTACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGAGCTAGCACTGCCCGGGCTGACT
ACTTTGCTCAAAAACAAAGAAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGTGACACTGGCCTC
CAGCCTCAATCTGTTCCGTAGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGAGG
CCAGCCCCTGGCTCACTGGCACAGGGCAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATG
GGACGGAAGTCTGCTTGGCAGTGGCTTTGATAAGCGATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTT

>6240_6240_3_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000319670_MAPKAP1_chr9_128230388_ENST00000373497_length(amino acids)=269AA_BP=147
MREWQRSWRRAACGRSGRASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPAGPGTQLGPITGEMDEADSAFLKFKQTADDSLS
LTSPNTESIFVEDPYTASLRSEIESDGHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYGISGDKVEIDPVTNQKASTKFWIKQKPISID

--------------------------------------------------------------
>6240_6240_4_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000319670_MAPKAP1_chr9_128230388_ENST00000373498_length(transcript)=2383nt_BP=528nt
CTCGCGCGGCTTCCCGCTTCCGGCTCCCAGCTGCTAGCTACTGTGGATCTGGGGGGGCCGGACGGAGGCATCGGAGGCGGCTGCGAGAGT
GGCAGAGGAGCTGGCGGAGAGCGGCCTGCGGGCGATCGGGCCGAGCCTCGCTCAAGGAGCACCCCCGGGGCACCCTCCTGTCCGATGGCA
GCCCGGCCCTGTCCAGGAATGTCGGTATGACGGTCTCTCAGAAAGGGGGTCCCCAGCCAACACCGAGCCCGGCTGGCCCTGGGACGCAAC
TCGGACCAATCACAGGAGAGATGGATGAAGCCGATTCTGCGTTTTTAAAATTTAAGCAGACAGCTGATGACTCTCTGTCCCTTACATCTC
CAAACACCGAGTCCATTTTTGTAGAAGATCCCTACACCGCCTCGCTGAGGAGTGAGATTGAGTCAGACGGCCACGAGTTTGAAGCTGAGT
CCTGGAGCCTCGCCGTGGATGCAGCCTACGCCAAGAAGCAAAAGAGGGAGGTGGTGAAAAGACAAGATGTCCTTTATGGTATCTCTGGAG
ACAAAGTAGAGATAGACCCTGTTACGAATCAGAAAGCCAGCACTAAGTTTTGGATTAAGCAGAAACCCATCTCAATCGATTCCGACCTGC
TCTGTGCCTGTGACCTTGCTGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCACGTATCTAAGCAATCACGACTATAAACACCTCT
ACTTTGAATCGGACGCTGCTACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGAGCTAGCACTGCCCGGGCTGACT
ACTTTGCTCAAAAACAAAGAAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGTGACACTGGCCTC
CAGCCTCAATCTGTTCCGTAGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGAGG
CCAGCCCCTGGCTCACTGGCACAGGGCAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATG
GGACGGAAGTCTGCTTGGCAGTGGCTTTGATAAGCGATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTT
CAATGCCTGCCACCCTGCCCGAGGATGTACAGAGCCGTGCCCACACATTTCCTTGCAACTTGATCAAATTTCTTAAAGCAAACAACAAAA
ATGTACATTTCTGTTTTTCCTTTTAATAAACAGGTGTACTCTTTATCATGGTTGGTATGATGGACCATTCTTTGGGGCGGAGGATTGATT
ATGTTACTCTCTTTAAAATCTGTTCCCATATTGAACAGGCAGATTGGAAAAGCTATGGTTCGATTTCTCAGAAGAAATGTTTAGGTCTTA
GTCAATAGTTTTAACTATGCCATTTGTTTAAATGAGTGCATTTGCTTCGAGGGTAGTGTCTTACTAAAAGTTAGGAACAGAGACCTAGTG
GTGTGTCCAAGGCCGTGTCACTTTCCCCTTCAGCACACCCCAGCTTCTGACCTCAGAGCCCAGGAGCTGCGTGGACAGTGTGGGGTGCCA
GGAGGAGGGGCGGTGGCTGGTCCTCAGGCACGCTGCACTCCCAGCCAGACATGGTCTTTCCGTTTCTTAAGTAGCAAGTGTAGGTTTCAG
CTGGCAGTTCCACCTGCATGTTCTCTGCTTCGCTGCCTTGGAAGGGGCCACATTCCCCATTCCTCTTCTCCTTACAGCGCCTGCCTCCTT
TTTCAAGCAGGCGGAAAGCTGCTGTTTCTCACGTTTCAGGGAGAGGGGTGAGCGGAGGGAGACCTGTGTCCGTGCCGTCCGGCTCCCTGG
GTGGGAACAGGCAAGGGATCAGATGCCCCTGACACCACGCCTCTGGCCACACCAGATGCCTCTGCAGTCCTCGACAGCCTCTTCAGTGTC
CCTCCTGCGGTGATGTCCTTACTGTCCCCAGCCAGGGCCGGGGACCGGTGTTTCACTGAGGACCTGCATTAGAAACATTTTTTAAATTGT
TGTACAGGAAGAGATGTGTCTAAAACAGCATCTTAAAGCTGAGTGTATTTCTTTGCACAAGGGGTCATGCTGATGAATTCTTCTTTCATT
CTGATCTTTGTTCAGCCAACAGGAGCGTCCTTTTCTAATGTCTTCCATTCCTACCCCCCACCCAAAAACAAAAGAAATATTTGTAGCTTG
CTATCTGTATTTGAATTTTTAGCAATTTTATATTTAGATACTTTGAAAAATGTAAATGACTAATTTGGTCATTAAATCTTGTGACATATT

>6240_6240_4_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000319670_MAPKAP1_chr9_128230388_ENST00000373498_length(amino acids)=269AA_BP=147
MREWQRSWRRAACGRSGRASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPAGPGTQLGPITGEMDEADSAFLKFKQTADDSLS
LTSPNTESIFVEDPYTASLRSEIESDGHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYGISGDKVEIDPVTNQKASTKFWIKQKPISID

--------------------------------------------------------------
>6240_6240_5_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000319670_MAPKAP1_chr9_128230388_ENST00000373503_length(transcript)=2383nt_BP=528nt
CTCGCGCGGCTTCCCGCTTCCGGCTCCCAGCTGCTAGCTACTGTGGATCTGGGGGGGCCGGACGGAGGCATCGGAGGCGGCTGCGAGAGT
GGCAGAGGAGCTGGCGGAGAGCGGCCTGCGGGCGATCGGGCCGAGCCTCGCTCAAGGAGCACCCCCGGGGCACCCTCCTGTCCGATGGCA
GCCCGGCCCTGTCCAGGAATGTCGGTATGACGGTCTCTCAGAAAGGGGGTCCCCAGCCAACACCGAGCCCGGCTGGCCCTGGGACGCAAC
TCGGACCAATCACAGGAGAGATGGATGAAGCCGATTCTGCGTTTTTAAAATTTAAGCAGACAGCTGATGACTCTCTGTCCCTTACATCTC
CAAACACCGAGTCCATTTTTGTAGAAGATCCCTACACCGCCTCGCTGAGGAGTGAGATTGAGTCAGACGGCCACGAGTTTGAAGCTGAGT
CCTGGAGCCTCGCCGTGGATGCAGCCTACGCCAAGAAGCAAAAGAGGGAGGTGGTGAAAAGACAAGATGTCCTTTATGGTATCTCTGGAG
ACAAAGTAGAGATAGACCCTGTTACGAATCAGAAAGCCAGCACTAAGTTTTGGATTAAGCAGAAACCCATCTCAATCGATTCCGACCTGC
TCTGTGCCTGTGACCTTGCTGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCACGTATCTAAGCAATCACGACTATAAACACCTCT
ACTTTGAATCGGACGCTGCTACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGAGCTAGCACTGCCCGGGCTGACT
ACTTTGCTCAAAAACAAAGAAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGTGACACTGGCCTC
CAGCCTCAATCTGTTCCGTAGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGAGG
CCAGCCCCTGGCTCACTGGCACAGGGCAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATG
GGACGGAAGTCTGCTTGGCAGTGGCTTTGATAAGCGATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTT
CAATGCCTGCCACCCTGCCCGAGGATGTACAGAGCCGTGCCCACACATTTCCTTGCAACTTGATCAAATTTCTTAAAGCAAACAACAAAA
ATGTACATTTCTGTTTTTCCTTTTAATAAACAGGTGTACTCTTTATCATGGTTGGTATGATGGACCATTCTTTGGGGCGGAGGATTGATT
ATGTTACTCTCTTTAAAATCTGTTCCCATATTGAACAGGCAGATTGGAAAAGCTATGGTTCGATTTCTCAGAAGAAATGTTTAGGTCTTA
GTCAATAGTTTTAACTATGCCATTTGTTTAAATGAGTGCATTTGCTTCGAGGGTAGTGTCTTACTAAAAGTTAGGAACAGAGACCTAGTG
GTGTGTCCAAGGCCGTGTCACTTTCCCCTTCAGCACACCCCAGCTTCTGACCTCAGAGCCCAGGAGCTGCGTGGACAGTGTGGGGTGCCA
GGAGGAGGGGCGGTGGCTGGTCCTCAGGCACGCTGCACTCCCAGCCAGACATGGTCTTTCCGTTTCTTAAGTAGCAAGTGTAGGTTTCAG
CTGGCAGTTCCACCTGCATGTTCTCTGCTTCGCTGCCTTGGAAGGGGCCACATTCCCCATTCCTCTTCTCCTTACAGCGCCTGCCTCCTT
TTTCAAGCAGGCGGAAAGCTGCTGTTTCTCACGTTTCAGGGAGAGGGGTGAGCGGAGGGAGACCTGTGTCCGTGCCGTCCGGCTCCCTGG
GTGGGAACAGGCAAGGGATCAGATGCCCCTGACACCACGCCTCTGGCCACACCAGATGCCTCTGCAGTCCTCGACAGCCTCTTCAGTGTC
CCTCCTGCGGTGATGTCCTTACTGTCCCCAGCCAGGGCCGGGGACCGGTGTTTCACTGAGGACCTGCATTAGAAACATTTTTTAAATTGT
TGTACAGGAAGAGATGTGTCTAAAACAGCATCTTAAAGCTGAGTGTATTTCTTTGCACAAGGGGTCATGCTGATGAATTCTTCTTTCATT
CTGATCTTTGTTCAGCCAACAGGAGCGTCCTTTTCTAATGTCTTCCATTCCTACCCCCCACCCAAAAACAAAAGAAATATTTGTAGCTTG
CTATCTGTATTTGAATTTTTAGCAATTTTATATTTAGATACTTTGAAAAATGTAAATGACTAATTTGGTCATTAAATCTTGTGACATATT

>6240_6240_5_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000319670_MAPKAP1_chr9_128230388_ENST00000373503_length(amino acids)=269AA_BP=147
MREWQRSWRRAACGRSGRASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPAGPGTQLGPITGEMDEADSAFLKFKQTADDSLS
LTSPNTESIFVEDPYTASLRSEIESDGHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYGISGDKVEIDPVTNQKASTKFWIKQKPISID

--------------------------------------------------------------
>6240_6240_6_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000319670_MAPKAP1_chr9_128230388_ENST00000373511_length(transcript)=2384nt_BP=528nt
CTCGCGCGGCTTCCCGCTTCCGGCTCCCAGCTGCTAGCTACTGTGGATCTGGGGGGGCCGGACGGAGGCATCGGAGGCGGCTGCGAGAGT
GGCAGAGGAGCTGGCGGAGAGCGGCCTGCGGGCGATCGGGCCGAGCCTCGCTCAAGGAGCACCCCCGGGGCACCCTCCTGTCCGATGGCA
GCCCGGCCCTGTCCAGGAATGTCGGTATGACGGTCTCTCAGAAAGGGGGTCCCCAGCCAACACCGAGCCCGGCTGGCCCTGGGACGCAAC
TCGGACCAATCACAGGAGAGATGGATGAAGCCGATTCTGCGTTTTTAAAATTTAAGCAGACAGCTGATGACTCTCTGTCCCTTACATCTC
CAAACACCGAGTCCATTTTTGTAGAAGATCCCTACACCGCCTCGCTGAGGAGTGAGATTGAGTCAGACGGCCACGAGTTTGAAGCTGAGT
CCTGGAGCCTCGCCGTGGATGCAGCCTACGCCAAGAAGCAAAAGAGGGAGGTGGTGAAAAGACAAGATGTCCTTTATGGTATCTCTGGAG
ACAAAGTAGAGATAGACCCTGTTACGAATCAGAAAGCCAGCACTAAGTTTTGGATTAAGCAGAAACCCATCTCAATCGATTCCGACCTGC
TCTGTGCCTGTGACCTTGCTGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCACGTATCTAAGCAATCACGACTATAAACACCTCT
ACTTTGAATCGGACGCTGCTACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGAGCTAGCACTGCCCGGGCTGACT
ACTTTGCTCAAAAACAAAGAAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGTGACACTGGCCTC
CAGCCTCAATCTGTTCCGTAGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGAGG
CCAGCCCCTGGCTCACTGGCACAGGGCAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATG
GGACGGAAGTCTGCTTGGCAGTGGCTTTGATAAGCGATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTT
CAATGCCTGCCACCCTGCCCGAGGATGTACAGAGCCGTGCCCACACATTTCCTTGCAACTTGATCAAATTTCTTAAAGCAAACAACAAAA
ATGTACATTTCTGTTTTTCCTTTTAATAAACAGGTGTACTCTTTATCATGGTTGGTATGATGGACCATTCTTTGGGGCGGAGGATTGATT
ATGTTACTCTCTTTAAAATCTGTTCCCATATTGAACAGGCAGATTGGAAAAGCTATGGTTCGATTTCTCAGAAGAAATGTTTAGGTCTTA
GTCAATAGTTTTAACTATGCCATTTGTTTAAATGAGTGCATTTGCTTCGAGGGTAGTGTCTTACTAAAAGTTAGGAACAGAGACCTAGTG
GTGTGTCCAAGGCCGTGTCACTTTCCCCTTCAGCACACCCCAGCTTCTGACCTCAGAGCCCAGGAGCTGCGTGGACAGTGTGGGGTGCCA
GGAGGAGGGGCGGTGGCTGGTCCTCAGGCACGCTGCACTCCCAGCCAGACATGGTCTTTCCGTTTCTTAAGTAGCAAGTGTAGGTTTCAG
CTGGCAGTTCCACCTGCATGTTCTCTGCTTCGCTGCCTTGGAAGGGGCCACATTCCCCATTCCTCTTCTCCTTACAGCGCCTGCCTCCTT
TTTCAAGCAGGCGGAAAGCTGCTGTTTCTCACGTTTCAGGGAGAGGGGTGAGCGGAGGGAGACCTGTGTCCGTGCCGTCCGGCTCCCTGG
GTGGGAACAGGCAAGGGATCAGATGCCCCTGACACCACGCCTCTGGCCACACCAGATGCCTCTGCAGTCCTCGACAGCCTCTTCAGTGTC
CCTCCTGCGGTGATGTCCTTACTGTCCCCAGCCAGGGCCGGGGACCGGTGTTTCACTGAGGACCTGCATTAGAAACATTTTTTAAATTGT
TGTACAGGAAGAGATGTGTCTAAAACAGCATCTTAAAGCTGAGTGTATTTCTTTGCACAAGGGGTCATGCTGATGAATTCTTCTTTCATT
CTGATCTTTGTTCAGCCAACAGGAGCGTCCTTTTCTAATGTCTTCCATTCCTACCCCCCACCCAAAAACAAAAGAAATATTTGTAGCTTG
CTATCTGTATTTGAATTTTTAGCAATTTTATATTTAGATACTTTGAAAAATGTAAATGACTAATTTGGTCATTAAATCTTGTGACATATT

>6240_6240_6_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000319670_MAPKAP1_chr9_128230388_ENST00000373511_length(amino acids)=269AA_BP=147
MREWQRSWRRAACGRSGRASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPAGPGTQLGPITGEMDEADSAFLKFKQTADDSLS
LTSPNTESIFVEDPYTASLRSEIESDGHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYGISGDKVEIDPVTNQKASTKFWIKQKPISID

--------------------------------------------------------------
>6240_6240_7_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000319670_MAPKAP1_chr9_128230388_ENST00000394063_length(transcript)=2383nt_BP=528nt
CTCGCGCGGCTTCCCGCTTCCGGCTCCCAGCTGCTAGCTACTGTGGATCTGGGGGGGCCGGACGGAGGCATCGGAGGCGGCTGCGAGAGT
GGCAGAGGAGCTGGCGGAGAGCGGCCTGCGGGCGATCGGGCCGAGCCTCGCTCAAGGAGCACCCCCGGGGCACCCTCCTGTCCGATGGCA
GCCCGGCCCTGTCCAGGAATGTCGGTATGACGGTCTCTCAGAAAGGGGGTCCCCAGCCAACACCGAGCCCGGCTGGCCCTGGGACGCAAC
TCGGACCAATCACAGGAGAGATGGATGAAGCCGATTCTGCGTTTTTAAAATTTAAGCAGACAGCTGATGACTCTCTGTCCCTTACATCTC
CAAACACCGAGTCCATTTTTGTAGAAGATCCCTACACCGCCTCGCTGAGGAGTGAGATTGAGTCAGACGGCCACGAGTTTGAAGCTGAGT
CCTGGAGCCTCGCCGTGGATGCAGCCTACGCCAAGAAGCAAAAGAGGGAGGTGGTGAAAAGACAAGATGTCCTTTATGGTATCTCTGGAG
ACAAAGTAGAGATAGACCCTGTTACGAATCAGAAAGCCAGCACTAAGTTTTGGATTAAGCAGAAACCCATCTCAATCGATTCCGACCTGC
TCTGTGCCTGTGACCTTGCTGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCACGTATCTAAGCAATCACGACTATAAACACCTCT
ACTTTGAATCGGACGCTGCTACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGAGCTAGCACTGCCCGGGCTGACT
ACTTTGCTCAAAAACAAAGAAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGTGACACTGGCCTC
CAGCCTCAATCTGTTCCGTAGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGAGG
CCAGCCCCTGGCTCACTGGCACAGGGCAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATG
GGACGGAAGTCTGCTTGGCAGTGGCTTTGATAAGCGATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTT
CAATGCCTGCCACCCTGCCCGAGGATGTACAGAGCCGTGCCCACACATTTCCTTGCAACTTGATCAAATTTCTTAAAGCAAACAACAAAA
ATGTACATTTCTGTTTTTCCTTTTAATAAACAGGTGTACTCTTTATCATGGTTGGTATGATGGACCATTCTTTGGGGCGGAGGATTGATT
ATGTTACTCTCTTTAAAATCTGTTCCCATATTGAACAGGCAGATTGGAAAAGCTATGGTTCGATTTCTCAGAAGAAATGTTTAGGTCTTA
GTCAATAGTTTTAACTATGCCATTTGTTTAAATGAGTGCATTTGCTTCGAGGGTAGTGTCTTACTAAAAGTTAGGAACAGAGACCTAGTG
GTGTGTCCAAGGCCGTGTCACTTTCCCCTTCAGCACACCCCAGCTTCTGACCTCAGAGCCCAGGAGCTGCGTGGACAGTGTGGGGTGCCA
GGAGGAGGGGCGGTGGCTGGTCCTCAGGCACGCTGCACTCCCAGCCAGACATGGTCTTTCCGTTTCTTAAGTAGCAAGTGTAGGTTTCAG
CTGGCAGTTCCACCTGCATGTTCTCTGCTTCGCTGCCTTGGAAGGGGCCACATTCCCCATTCCTCTTCTCCTTACAGCGCCTGCCTCCTT
TTTCAAGCAGGCGGAAAGCTGCTGTTTCTCACGTTTCAGGGAGAGGGGTGAGCGGAGGGAGACCTGTGTCCGTGCCGTCCGGCTCCCTGG
GTGGGAACAGGCAAGGGATCAGATGCCCCTGACACCACGCCTCTGGCCACACCAGATGCCTCTGCAGTCCTCGACAGCCTCTTCAGTGTC
CCTCCTGCGGTGATGTCCTTACTGTCCCCAGCCAGGGCCGGGGACCGGTGTTTCACTGAGGACCTGCATTAGAAACATTTTTTAAATTGT
TGTACAGGAAGAGATGTGTCTAAAACAGCATCTTAAAGCTGAGTGTATTTCTTTGCACAAGGGGTCATGCTGATGAATTCTTCTTTCATT
CTGATCTTTGTTCAGCCAACAGGAGCGTCCTTTTCTAATGTCTTCCATTCCTACCCCCCACCCAAAAACAAAAGAAATATTTGTAGCTTG
CTATCTGTATTTGAATTTTTAGCAATTTTATATTTAGATACTTTGAAAAATGTAAATGACTAATTTGGTCATTAAATCTTGTGACATATT

>6240_6240_7_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000319670_MAPKAP1_chr9_128230388_ENST00000394063_length(amino acids)=269AA_BP=147
MREWQRSWRRAACGRSGRASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPAGPGTQLGPITGEMDEADSAFLKFKQTADDSLS
LTSPNTESIFVEDPYTASLRSEIESDGHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYGISGDKVEIDPVTNQKASTKFWIKQKPISID

--------------------------------------------------------------
>6240_6240_8_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000359920_MAPKAP1_chr9_128230388_ENST00000265960_length(transcript)=2904nt_BP=1049nt
AAACACCATGCCCTGCCATCTCTGGGTCTTAGAGTCACCCTAACATCTGATCTAGATTAATTATCATCATGTGCGAGGTTTTGGCATGAA
GCACGCCAGGCTCACCGTTTCATGATCTTAGACTATTTACAGCAAACTCAAACAGCTCACTTGCTTTTTACACCCTGCAAAGACCAAGGG
AGAGCCTGGAGGGGTTGTTTTTTTTTTCTGTTTTATTCTATCAAAGCAGCAAATACTGCAATTTCCACAGTAAATGGTCACAGTGGGGAC
CAATATCCTGCCCTCCAGACCCGCTGCTTCAGCCAATACAGCAAGGGAAGACGCAGCTCTGTTTTCTAGAAGGATCCCACCGAGGCATAA
AAACGGCGCAGCCCAGCCTGGCGCCGCGCCGGGTCCCGGAGCCCCGGGCGCGAACATGGGGAATGCGCACTCCAAAAGCGGGGACAGGCA
CAGCGCGCTCCCCGGCCGCCCCGAGCTGTCTTTTTACGGCTCTTTCCCCAGGAAATGGAGCGAGAACGTCTTCTTGGATAACGAGCTGCT
GACCTCCAAGATCCTGTCTGTGCTGCGGCCGCAGTCGGAGCGGGGCTTCCGCGCCGGGGACCTCCGCTACCCGACCCACTTTCTCAGCAC
CAACTCTGTCCTTGCCTCTGTCACAGCCTCGCTCAAGGAGCACCCCCGGGGCACCCTCCTGTCCGATGGCAGCCCGGCCCTGTCCAGGAA
TGTCGGTATGACGGTCTCTCAGAAAGGGGGTCCCCAGCCAACACCGAGCCCGGCTGGCCCTGGGACGCAACTCGGACCAATCACAGGAGA
GATGGATGAAGCCGATTCTGCGTTTTTAAAATTTAAGCAGACAGCTGATGACTCTCTGTCCCTTACATCTCCAAACACCGAGTCCATTTT
TGTAGAAGATCCCTACACCGCCTCGCTGAGGAGTGAGATTGAGTCAGACGGCCACGAGTTTGAAGCTGAGTCCTGGAGCCTCGCCGTGGA
TGCAGCCTACGCCAAGAAGCAAAAGAGGGAGGTGGTGAAAAGACAAGATGTCCTTTATGGTATCTCTGGAGACAAAGTAGAGATAGACCC
TGTTACGAATCAGAAAGCCAGCACTAAGTTTTGGATTAAGCAGAAACCCATCTCAATCGATTCCGACCTGCTCTGTGCCTGTGACCTTGC
TGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCACGTATCTAAGCAATCACGACTATAAACACCTCTACTTTGAATCGGACGCTGC
TACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGAGCTAGCACTGCCCGGGCTGACTACTTTGCTCAAAAACAAAG
AAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGTGACACTGGCCTCCAGCCTCAATCTGTTCCGT
AGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGAGGCCAGCCCCTGGCTCACTGG
CACAGGGCAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATGGGACGGAAGTCTGCTTGGC
AGTGGCTTTGATAAGCGATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTTCAATGCCTGCCACCCTGCC
CGAGGATGTACAGAGCCGTGCCCACACATTTCCTTGCAACTTGATCAAATTTCTTAAAGCAAACAACAAAAATGTACATTTCTGTTTTTC
CTTTTAATAAACAGGTGTACTCTTTATCATGGTTGGTATGATGGACCATTCTTTGGGGCGGAGGATTGATTATGTTACTCTCTTTAAAAT
CTGTTCCCATATTGAACAGGCAGATTGGAAAAGCTATGGTTCGATTTCTCAGAAGAAATGTTTAGGTCTTAGTCAATAGTTTTAACTATG
CCATTTGTTTAAATGAGTGCATTTGCTTCGAGGGTAGTGTCTTACTAAAAGTTAGGAACAGAGACCTAGTGGTGTGTCCAAGGCCGTGTC
ACTTTCCCCTTCAGCACACCCCAGCTTCTGACCTCAGAGCCCAGGAGCTGCGTGGACAGTGTGGGGTGCCAGGAGGAGGGGCGGTGGCTG
GTCCTCAGGCACGCTGCACTCCCAGCCAGACATGGTCTTTCCGTTTCTTAAGTAGCAAGTGTAGGTTTCAGCTGGCAGTTCCACCTGCAT
GTTCTCTGCTTCGCTGCCTTGGAAGGGGCCACATTCCCCATTCCTCTTCTCCTTACAGCGCCTGCCTCCTTTTTCAAGCAGGCGGAAAGC
TGCTGTTTCTCACGTTTCAGGGAGAGGGGTGAGCGGAGGGAGACCTGTGTCCGTGCCGTCCGGCTCCCTGGGTGGGAACAGGCAAGGGAT
CAGATGCCCCTGACACCACGCCTCTGGCCACACCAGATGCCTCTGCAGTCCTCGACAGCCTCTTCAGTGTCCCTCCTGCGGTGATGTCCT
TACTGTCCCCAGCCAGGGCCGGGGACCGGTGTTTCACTGAGGACCTGCATTAGAAACATTTTTTAAATTGTTGTACAGGAAGAGATGTGT
CTAAAACAGCATCTTAAAGCTGAGTGTATTTCTTTGCACAAGGGGTCATGCTGATGAATTCTTCTTTCATTCTGATCTTTGTTCAGCCAA
CAGGAGCGTCCTTTTCTAATGTCTTCCATTCCTACCCCCCACCCAAAAACAAAAGAAATATTTGTAGCTTGCTATCTGTATTTGAATTTT
TAGCAATTTTATATTTAGATACTTTGAAAAATGTAAATGACTAATTTGGTCATTAAATCTTGTGACATATTCGATATTAAAATGATATTA

>6240_6240_8_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000359920_MAPKAP1_chr9_128230388_ENST00000265960_length(amino acids)=385AA_BP=263
MVTVGTNILPSRPAASANTAREDAALFSRRIPPRHKNGAAQPGAAPGPGAPGANMGNAHSKSGDRHSALPGRPELSFYGSFPRKWSENVF
LDNELLTSKILSVLRPQSERGFRAGDLRYPTHFLSTNSVLASVTASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPAGPGTQL
GPITGEMDEADSAFLKFKQTADDSLSLTSPNTESIFVEDPYTASLRSEIESDGHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYGISGD
KVEIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFESDAATVNEIVLKVNYILESRASTARADY

--------------------------------------------------------------
>6240_6240_9_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000359920_MAPKAP1_chr9_128230388_ENST00000350766_length(transcript)=2904nt_BP=1049nt
AAACACCATGCCCTGCCATCTCTGGGTCTTAGAGTCACCCTAACATCTGATCTAGATTAATTATCATCATGTGCGAGGTTTTGGCATGAA
GCACGCCAGGCTCACCGTTTCATGATCTTAGACTATTTACAGCAAACTCAAACAGCTCACTTGCTTTTTACACCCTGCAAAGACCAAGGG
AGAGCCTGGAGGGGTTGTTTTTTTTTTCTGTTTTATTCTATCAAAGCAGCAAATACTGCAATTTCCACAGTAAATGGTCACAGTGGGGAC
CAATATCCTGCCCTCCAGACCCGCTGCTTCAGCCAATACAGCAAGGGAAGACGCAGCTCTGTTTTCTAGAAGGATCCCACCGAGGCATAA
AAACGGCGCAGCCCAGCCTGGCGCCGCGCCGGGTCCCGGAGCCCCGGGCGCGAACATGGGGAATGCGCACTCCAAAAGCGGGGACAGGCA
CAGCGCGCTCCCCGGCCGCCCCGAGCTGTCTTTTTACGGCTCTTTCCCCAGGAAATGGAGCGAGAACGTCTTCTTGGATAACGAGCTGCT
GACCTCCAAGATCCTGTCTGTGCTGCGGCCGCAGTCGGAGCGGGGCTTCCGCGCCGGGGACCTCCGCTACCCGACCCACTTTCTCAGCAC
CAACTCTGTCCTTGCCTCTGTCACAGCCTCGCTCAAGGAGCACCCCCGGGGCACCCTCCTGTCCGATGGCAGCCCGGCCCTGTCCAGGAA
TGTCGGTATGACGGTCTCTCAGAAAGGGGGTCCCCAGCCAACACCGAGCCCGGCTGGCCCTGGGACGCAACTCGGACCAATCACAGGAGA
GATGGATGAAGCCGATTCTGCGTTTTTAAAATTTAAGCAGACAGCTGATGACTCTCTGTCCCTTACATCTCCAAACACCGAGTCCATTTT
TGTAGAAGATCCCTACACCGCCTCGCTGAGGAGTGAGATTGAGTCAGACGGCCACGAGTTTGAAGCTGAGTCCTGGAGCCTCGCCGTGGA
TGCAGCCTACGCCAAGAAGCAAAAGAGGGAGGTGGTGAAAAGACAAGATGTCCTTTATGGTATCTCTGGAGACAAAGTAGAGATAGACCC
TGTTACGAATCAGAAAGCCAGCACTAAGTTTTGGATTAAGCAGAAACCCATCTCAATCGATTCCGACCTGCTCTGTGCCTGTGACCTTGC
TGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCACGTATCTAAGCAATCACGACTATAAACACCTCTACTTTGAATCGGACGCTGC
TACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGAGCTAGCACTGCCCGGGCTGACTACTTTGCTCAAAAACAAAG
AAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGTGACACTGGCCTCCAGCCTCAATCTGTTCCGT
AGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGAGGCCAGCCCCTGGCTCACTGG
CACAGGGCAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATGGGACGGAAGTCTGCTTGGC
AGTGGCTTTGATAAGCGATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTTCAATGCCTGCCACCCTGCC
CGAGGATGTACAGAGCCGTGCCCACACATTTCCTTGCAACTTGATCAAATTTCTTAAAGCAAACAACAAAAATGTACATTTCTGTTTTTC
CTTTTAATAAACAGGTGTACTCTTTATCATGGTTGGTATGATGGACCATTCTTTGGGGCGGAGGATTGATTATGTTACTCTCTTTAAAAT
CTGTTCCCATATTGAACAGGCAGATTGGAAAAGCTATGGTTCGATTTCTCAGAAGAAATGTTTAGGTCTTAGTCAATAGTTTTAACTATG
CCATTTGTTTAAATGAGTGCATTTGCTTCGAGGGTAGTGTCTTACTAAAAGTTAGGAACAGAGACCTAGTGGTGTGTCCAAGGCCGTGTC
ACTTTCCCCTTCAGCACACCCCAGCTTCTGACCTCAGAGCCCAGGAGCTGCGTGGACAGTGTGGGGTGCCAGGAGGAGGGGCGGTGGCTG
GTCCTCAGGCACGCTGCACTCCCAGCCAGACATGGTCTTTCCGTTTCTTAAGTAGCAAGTGTAGGTTTCAGCTGGCAGTTCCACCTGCAT
GTTCTCTGCTTCGCTGCCTTGGAAGGGGCCACATTCCCCATTCCTCTTCTCCTTACAGCGCCTGCCTCCTTTTTCAAGCAGGCGGAAAGC
TGCTGTTTCTCACGTTTCAGGGAGAGGGGTGAGCGGAGGGAGACCTGTGTCCGTGCCGTCCGGCTCCCTGGGTGGGAACAGGCAAGGGAT
CAGATGCCCCTGACACCACGCCTCTGGCCACACCAGATGCCTCTGCAGTCCTCGACAGCCTCTTCAGTGTCCCTCCTGCGGTGATGTCCT
TACTGTCCCCAGCCAGGGCCGGGGACCGGTGTTTCACTGAGGACCTGCATTAGAAACATTTTTTAAATTGTTGTACAGGAAGAGATGTGT
CTAAAACAGCATCTTAAAGCTGAGTGTATTTCTTTGCACAAGGGGTCATGCTGATGAATTCTTCTTTCATTCTGATCTTTGTTCAGCCAA
CAGGAGCGTCCTTTTCTAATGTCTTCCATTCCTACCCCCCACCCAAAAACAAAAGAAATATTTGTAGCTTGCTATCTGTATTTGAATTTT
TAGCAATTTTATATTTAGATACTTTGAAAAATGTAAATGACTAATTTGGTCATTAAATCTTGTGACATATTCGATATTAAAATGATATTA

>6240_6240_9_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000359920_MAPKAP1_chr9_128230388_ENST00000350766_length(amino acids)=385AA_BP=263
MVTVGTNILPSRPAASANTAREDAALFSRRIPPRHKNGAAQPGAAPGPGAPGANMGNAHSKSGDRHSALPGRPELSFYGSFPRKWSENVF
LDNELLTSKILSVLRPQSERGFRAGDLRYPTHFLSTNSVLASVTASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPAGPGTQL
GPITGEMDEADSAFLKFKQTADDSLSLTSPNTESIFVEDPYTASLRSEIESDGHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYGISGD
KVEIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFESDAATVNEIVLKVNYILESRASTARADY

--------------------------------------------------------------
>6240_6240_10_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000359920_MAPKAP1_chr9_128230388_ENST00000373497_length(transcript)=1765nt_BP=1049nt
AAACACCATGCCCTGCCATCTCTGGGTCTTAGAGTCACCCTAACATCTGATCTAGATTAATTATCATCATGTGCGAGGTTTTGGCATGAA
GCACGCCAGGCTCACCGTTTCATGATCTTAGACTATTTACAGCAAACTCAAACAGCTCACTTGCTTTTTACACCCTGCAAAGACCAAGGG
AGAGCCTGGAGGGGTTGTTTTTTTTTTCTGTTTTATTCTATCAAAGCAGCAAATACTGCAATTTCCACAGTAAATGGTCACAGTGGGGAC
CAATATCCTGCCCTCCAGACCCGCTGCTTCAGCCAATACAGCAAGGGAAGACGCAGCTCTGTTTTCTAGAAGGATCCCACCGAGGCATAA
AAACGGCGCAGCCCAGCCTGGCGCCGCGCCGGGTCCCGGAGCCCCGGGCGCGAACATGGGGAATGCGCACTCCAAAAGCGGGGACAGGCA
CAGCGCGCTCCCCGGCCGCCCCGAGCTGTCTTTTTACGGCTCTTTCCCCAGGAAATGGAGCGAGAACGTCTTCTTGGATAACGAGCTGCT
GACCTCCAAGATCCTGTCTGTGCTGCGGCCGCAGTCGGAGCGGGGCTTCCGCGCCGGGGACCTCCGCTACCCGACCCACTTTCTCAGCAC
CAACTCTGTCCTTGCCTCTGTCACAGCCTCGCTCAAGGAGCACCCCCGGGGCACCCTCCTGTCCGATGGCAGCCCGGCCCTGTCCAGGAA
TGTCGGTATGACGGTCTCTCAGAAAGGGGGTCCCCAGCCAACACCGAGCCCGGCTGGCCCTGGGACGCAACTCGGACCAATCACAGGAGA
GATGGATGAAGCCGATTCTGCGTTTTTAAAATTTAAGCAGACAGCTGATGACTCTCTGTCCCTTACATCTCCAAACACCGAGTCCATTTT
TGTAGAAGATCCCTACACCGCCTCGCTGAGGAGTGAGATTGAGTCAGACGGCCACGAGTTTGAAGCTGAGTCCTGGAGCCTCGCCGTGGA
TGCAGCCTACGCCAAGAAGCAAAAGAGGGAGGTGGTGAAAAGACAAGATGTCCTTTATGGTATCTCTGGAGACAAAGTAGAGATAGACCC
TGTTACGAATCAGAAAGCCAGCACTAAGTTTTGGATTAAGCAGAAACCCATCTCAATCGATTCCGACCTGCTCTGTGCCTGTGACCTTGC
TGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCACGTATCTAAGCAATCACGACTATAAACACCTCTACTTTGAATCGGACGCTGC
TACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGAGCTAGCACTGCCCGGGCTGACTACTTTGCTCAAAAACAAAG
AAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGTGACACTGGCCTCCAGCCTCAATCTGTTCCGT
AGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGAGGCCAGCCCCTGGCTCACTGG
CACAGGGCAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATGGGACGGAAGTCTGCTTGGC
AGTGGCTTTGATAAGCGATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTTCAATGCCTGCCACCCTGCC

>6240_6240_10_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000359920_MAPKAP1_chr9_128230388_ENST00000373497_length(amino acids)=385AA_BP=263
MVTVGTNILPSRPAASANTAREDAALFSRRIPPRHKNGAAQPGAAPGPGAPGANMGNAHSKSGDRHSALPGRPELSFYGSFPRKWSENVF
LDNELLTSKILSVLRPQSERGFRAGDLRYPTHFLSTNSVLASVTASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPAGPGTQL
GPITGEMDEADSAFLKFKQTADDSLSLTSPNTESIFVEDPYTASLRSEIESDGHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYGISGD
KVEIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFESDAATVNEIVLKVNYILESRASTARADY

--------------------------------------------------------------
>6240_6240_11_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000359920_MAPKAP1_chr9_128230388_ENST00000373498_length(transcript)=2904nt_BP=1049nt
AAACACCATGCCCTGCCATCTCTGGGTCTTAGAGTCACCCTAACATCTGATCTAGATTAATTATCATCATGTGCGAGGTTTTGGCATGAA
GCACGCCAGGCTCACCGTTTCATGATCTTAGACTATTTACAGCAAACTCAAACAGCTCACTTGCTTTTTACACCCTGCAAAGACCAAGGG
AGAGCCTGGAGGGGTTGTTTTTTTTTTCTGTTTTATTCTATCAAAGCAGCAAATACTGCAATTTCCACAGTAAATGGTCACAGTGGGGAC
CAATATCCTGCCCTCCAGACCCGCTGCTTCAGCCAATACAGCAAGGGAAGACGCAGCTCTGTTTTCTAGAAGGATCCCACCGAGGCATAA
AAACGGCGCAGCCCAGCCTGGCGCCGCGCCGGGTCCCGGAGCCCCGGGCGCGAACATGGGGAATGCGCACTCCAAAAGCGGGGACAGGCA
CAGCGCGCTCCCCGGCCGCCCCGAGCTGTCTTTTTACGGCTCTTTCCCCAGGAAATGGAGCGAGAACGTCTTCTTGGATAACGAGCTGCT
GACCTCCAAGATCCTGTCTGTGCTGCGGCCGCAGTCGGAGCGGGGCTTCCGCGCCGGGGACCTCCGCTACCCGACCCACTTTCTCAGCAC
CAACTCTGTCCTTGCCTCTGTCACAGCCTCGCTCAAGGAGCACCCCCGGGGCACCCTCCTGTCCGATGGCAGCCCGGCCCTGTCCAGGAA
TGTCGGTATGACGGTCTCTCAGAAAGGGGGTCCCCAGCCAACACCGAGCCCGGCTGGCCCTGGGACGCAACTCGGACCAATCACAGGAGA
GATGGATGAAGCCGATTCTGCGTTTTTAAAATTTAAGCAGACAGCTGATGACTCTCTGTCCCTTACATCTCCAAACACCGAGTCCATTTT
TGTAGAAGATCCCTACACCGCCTCGCTGAGGAGTGAGATTGAGTCAGACGGCCACGAGTTTGAAGCTGAGTCCTGGAGCCTCGCCGTGGA
TGCAGCCTACGCCAAGAAGCAAAAGAGGGAGGTGGTGAAAAGACAAGATGTCCTTTATGGTATCTCTGGAGACAAAGTAGAGATAGACCC
TGTTACGAATCAGAAAGCCAGCACTAAGTTTTGGATTAAGCAGAAACCCATCTCAATCGATTCCGACCTGCTCTGTGCCTGTGACCTTGC
TGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCACGTATCTAAGCAATCACGACTATAAACACCTCTACTTTGAATCGGACGCTGC
TACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGAGCTAGCACTGCCCGGGCTGACTACTTTGCTCAAAAACAAAG
AAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGTGACACTGGCCTCCAGCCTCAATCTGTTCCGT
AGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGAGGCCAGCCCCTGGCTCACTGG
CACAGGGCAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATGGGACGGAAGTCTGCTTGGC
AGTGGCTTTGATAAGCGATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTTCAATGCCTGCCACCCTGCC
CGAGGATGTACAGAGCCGTGCCCACACATTTCCTTGCAACTTGATCAAATTTCTTAAAGCAAACAACAAAAATGTACATTTCTGTTTTTC
CTTTTAATAAACAGGTGTACTCTTTATCATGGTTGGTATGATGGACCATTCTTTGGGGCGGAGGATTGATTATGTTACTCTCTTTAAAAT
CTGTTCCCATATTGAACAGGCAGATTGGAAAAGCTATGGTTCGATTTCTCAGAAGAAATGTTTAGGTCTTAGTCAATAGTTTTAACTATG
CCATTTGTTTAAATGAGTGCATTTGCTTCGAGGGTAGTGTCTTACTAAAAGTTAGGAACAGAGACCTAGTGGTGTGTCCAAGGCCGTGTC
ACTTTCCCCTTCAGCACACCCCAGCTTCTGACCTCAGAGCCCAGGAGCTGCGTGGACAGTGTGGGGTGCCAGGAGGAGGGGCGGTGGCTG
GTCCTCAGGCACGCTGCACTCCCAGCCAGACATGGTCTTTCCGTTTCTTAAGTAGCAAGTGTAGGTTTCAGCTGGCAGTTCCACCTGCAT
GTTCTCTGCTTCGCTGCCTTGGAAGGGGCCACATTCCCCATTCCTCTTCTCCTTACAGCGCCTGCCTCCTTTTTCAAGCAGGCGGAAAGC
TGCTGTTTCTCACGTTTCAGGGAGAGGGGTGAGCGGAGGGAGACCTGTGTCCGTGCCGTCCGGCTCCCTGGGTGGGAACAGGCAAGGGAT
CAGATGCCCCTGACACCACGCCTCTGGCCACACCAGATGCCTCTGCAGTCCTCGACAGCCTCTTCAGTGTCCCTCCTGCGGTGATGTCCT
TACTGTCCCCAGCCAGGGCCGGGGACCGGTGTTTCACTGAGGACCTGCATTAGAAACATTTTTTAAATTGTTGTACAGGAAGAGATGTGT
CTAAAACAGCATCTTAAAGCTGAGTGTATTTCTTTGCACAAGGGGTCATGCTGATGAATTCTTCTTTCATTCTGATCTTTGTTCAGCCAA
CAGGAGCGTCCTTTTCTAATGTCTTCCATTCCTACCCCCCACCCAAAAACAAAAGAAATATTTGTAGCTTGCTATCTGTATTTGAATTTT
TAGCAATTTTATATTTAGATACTTTGAAAAATGTAAATGACTAATTTGGTCATTAAATCTTGTGACATATTCGATATTAAAATGATATTA

>6240_6240_11_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000359920_MAPKAP1_chr9_128230388_ENST00000373498_length(amino acids)=385AA_BP=263
MVTVGTNILPSRPAASANTAREDAALFSRRIPPRHKNGAAQPGAAPGPGAPGANMGNAHSKSGDRHSALPGRPELSFYGSFPRKWSENVF
LDNELLTSKILSVLRPQSERGFRAGDLRYPTHFLSTNSVLASVTASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPAGPGTQL
GPITGEMDEADSAFLKFKQTADDSLSLTSPNTESIFVEDPYTASLRSEIESDGHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYGISGD
KVEIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFESDAATVNEIVLKVNYILESRASTARADY

--------------------------------------------------------------
>6240_6240_12_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000359920_MAPKAP1_chr9_128230388_ENST00000373503_length(transcript)=2904nt_BP=1049nt
AAACACCATGCCCTGCCATCTCTGGGTCTTAGAGTCACCCTAACATCTGATCTAGATTAATTATCATCATGTGCGAGGTTTTGGCATGAA
GCACGCCAGGCTCACCGTTTCATGATCTTAGACTATTTACAGCAAACTCAAACAGCTCACTTGCTTTTTACACCCTGCAAAGACCAAGGG
AGAGCCTGGAGGGGTTGTTTTTTTTTTCTGTTTTATTCTATCAAAGCAGCAAATACTGCAATTTCCACAGTAAATGGTCACAGTGGGGAC
CAATATCCTGCCCTCCAGACCCGCTGCTTCAGCCAATACAGCAAGGGAAGACGCAGCTCTGTTTTCTAGAAGGATCCCACCGAGGCATAA
AAACGGCGCAGCCCAGCCTGGCGCCGCGCCGGGTCCCGGAGCCCCGGGCGCGAACATGGGGAATGCGCACTCCAAAAGCGGGGACAGGCA
CAGCGCGCTCCCCGGCCGCCCCGAGCTGTCTTTTTACGGCTCTTTCCCCAGGAAATGGAGCGAGAACGTCTTCTTGGATAACGAGCTGCT
GACCTCCAAGATCCTGTCTGTGCTGCGGCCGCAGTCGGAGCGGGGCTTCCGCGCCGGGGACCTCCGCTACCCGACCCACTTTCTCAGCAC
CAACTCTGTCCTTGCCTCTGTCACAGCCTCGCTCAAGGAGCACCCCCGGGGCACCCTCCTGTCCGATGGCAGCCCGGCCCTGTCCAGGAA
TGTCGGTATGACGGTCTCTCAGAAAGGGGGTCCCCAGCCAACACCGAGCCCGGCTGGCCCTGGGACGCAACTCGGACCAATCACAGGAGA
GATGGATGAAGCCGATTCTGCGTTTTTAAAATTTAAGCAGACAGCTGATGACTCTCTGTCCCTTACATCTCCAAACACCGAGTCCATTTT
TGTAGAAGATCCCTACACCGCCTCGCTGAGGAGTGAGATTGAGTCAGACGGCCACGAGTTTGAAGCTGAGTCCTGGAGCCTCGCCGTGGA
TGCAGCCTACGCCAAGAAGCAAAAGAGGGAGGTGGTGAAAAGACAAGATGTCCTTTATGGTATCTCTGGAGACAAAGTAGAGATAGACCC
TGTTACGAATCAGAAAGCCAGCACTAAGTTTTGGATTAAGCAGAAACCCATCTCAATCGATTCCGACCTGCTCTGTGCCTGTGACCTTGC
TGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCACGTATCTAAGCAATCACGACTATAAACACCTCTACTTTGAATCGGACGCTGC
TACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGAGCTAGCACTGCCCGGGCTGACTACTTTGCTCAAAAACAAAG
AAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGTGACACTGGCCTCCAGCCTCAATCTGTTCCGT
AGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGAGGCCAGCCCCTGGCTCACTGG
CACAGGGCAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATGGGACGGAAGTCTGCTTGGC
AGTGGCTTTGATAAGCGATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTTCAATGCCTGCCACCCTGCC
CGAGGATGTACAGAGCCGTGCCCACACATTTCCTTGCAACTTGATCAAATTTCTTAAAGCAAACAACAAAAATGTACATTTCTGTTTTTC
CTTTTAATAAACAGGTGTACTCTTTATCATGGTTGGTATGATGGACCATTCTTTGGGGCGGAGGATTGATTATGTTACTCTCTTTAAAAT
CTGTTCCCATATTGAACAGGCAGATTGGAAAAGCTATGGTTCGATTTCTCAGAAGAAATGTTTAGGTCTTAGTCAATAGTTTTAACTATG
CCATTTGTTTAAATGAGTGCATTTGCTTCGAGGGTAGTGTCTTACTAAAAGTTAGGAACAGAGACCTAGTGGTGTGTCCAAGGCCGTGTC
ACTTTCCCCTTCAGCACACCCCAGCTTCTGACCTCAGAGCCCAGGAGCTGCGTGGACAGTGTGGGGTGCCAGGAGGAGGGGCGGTGGCTG
GTCCTCAGGCACGCTGCACTCCCAGCCAGACATGGTCTTTCCGTTTCTTAAGTAGCAAGTGTAGGTTTCAGCTGGCAGTTCCACCTGCAT
GTTCTCTGCTTCGCTGCCTTGGAAGGGGCCACATTCCCCATTCCTCTTCTCCTTACAGCGCCTGCCTCCTTTTTCAAGCAGGCGGAAAGC
TGCTGTTTCTCACGTTTCAGGGAGAGGGGTGAGCGGAGGGAGACCTGTGTCCGTGCCGTCCGGCTCCCTGGGTGGGAACAGGCAAGGGAT
CAGATGCCCCTGACACCACGCCTCTGGCCACACCAGATGCCTCTGCAGTCCTCGACAGCCTCTTCAGTGTCCCTCCTGCGGTGATGTCCT
TACTGTCCCCAGCCAGGGCCGGGGACCGGTGTTTCACTGAGGACCTGCATTAGAAACATTTTTTAAATTGTTGTACAGGAAGAGATGTGT
CTAAAACAGCATCTTAAAGCTGAGTGTATTTCTTTGCACAAGGGGTCATGCTGATGAATTCTTCTTTCATTCTGATCTTTGTTCAGCCAA
CAGGAGCGTCCTTTTCTAATGTCTTCCATTCCTACCCCCCACCCAAAAACAAAAGAAATATTTGTAGCTTGCTATCTGTATTTGAATTTT
TAGCAATTTTATATTTAGATACTTTGAAAAATGTAAATGACTAATTTGGTCATTAAATCTTGTGACATATTCGATATTAAAATGATATTA

>6240_6240_12_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000359920_MAPKAP1_chr9_128230388_ENST00000373503_length(amino acids)=385AA_BP=263
MVTVGTNILPSRPAASANTAREDAALFSRRIPPRHKNGAAQPGAAPGPGAPGANMGNAHSKSGDRHSALPGRPELSFYGSFPRKWSENVF
LDNELLTSKILSVLRPQSERGFRAGDLRYPTHFLSTNSVLASVTASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPAGPGTQL
GPITGEMDEADSAFLKFKQTADDSLSLTSPNTESIFVEDPYTASLRSEIESDGHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYGISGD
KVEIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFESDAATVNEIVLKVNYILESRASTARADY

--------------------------------------------------------------
>6240_6240_13_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000359920_MAPKAP1_chr9_128230388_ENST00000373511_length(transcript)=2905nt_BP=1049nt
AAACACCATGCCCTGCCATCTCTGGGTCTTAGAGTCACCCTAACATCTGATCTAGATTAATTATCATCATGTGCGAGGTTTTGGCATGAA
GCACGCCAGGCTCACCGTTTCATGATCTTAGACTATTTACAGCAAACTCAAACAGCTCACTTGCTTTTTACACCCTGCAAAGACCAAGGG
AGAGCCTGGAGGGGTTGTTTTTTTTTTCTGTTTTATTCTATCAAAGCAGCAAATACTGCAATTTCCACAGTAAATGGTCACAGTGGGGAC
CAATATCCTGCCCTCCAGACCCGCTGCTTCAGCCAATACAGCAAGGGAAGACGCAGCTCTGTTTTCTAGAAGGATCCCACCGAGGCATAA
AAACGGCGCAGCCCAGCCTGGCGCCGCGCCGGGTCCCGGAGCCCCGGGCGCGAACATGGGGAATGCGCACTCCAAAAGCGGGGACAGGCA
CAGCGCGCTCCCCGGCCGCCCCGAGCTGTCTTTTTACGGCTCTTTCCCCAGGAAATGGAGCGAGAACGTCTTCTTGGATAACGAGCTGCT
GACCTCCAAGATCCTGTCTGTGCTGCGGCCGCAGTCGGAGCGGGGCTTCCGCGCCGGGGACCTCCGCTACCCGACCCACTTTCTCAGCAC
CAACTCTGTCCTTGCCTCTGTCACAGCCTCGCTCAAGGAGCACCCCCGGGGCACCCTCCTGTCCGATGGCAGCCCGGCCCTGTCCAGGAA
TGTCGGTATGACGGTCTCTCAGAAAGGGGGTCCCCAGCCAACACCGAGCCCGGCTGGCCCTGGGACGCAACTCGGACCAATCACAGGAGA
GATGGATGAAGCCGATTCTGCGTTTTTAAAATTTAAGCAGACAGCTGATGACTCTCTGTCCCTTACATCTCCAAACACCGAGTCCATTTT
TGTAGAAGATCCCTACACCGCCTCGCTGAGGAGTGAGATTGAGTCAGACGGCCACGAGTTTGAAGCTGAGTCCTGGAGCCTCGCCGTGGA
TGCAGCCTACGCCAAGAAGCAAAAGAGGGAGGTGGTGAAAAGACAAGATGTCCTTTATGGTATCTCTGGAGACAAAGTAGAGATAGACCC
TGTTACGAATCAGAAAGCCAGCACTAAGTTTTGGATTAAGCAGAAACCCATCTCAATCGATTCCGACCTGCTCTGTGCCTGTGACCTTGC
TGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCACGTATCTAAGCAATCACGACTATAAACACCTCTACTTTGAATCGGACGCTGC
TACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGAGCTAGCACTGCCCGGGCTGACTACTTTGCTCAAAAACAAAG
AAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGTGACACTGGCCTCCAGCCTCAATCTGTTCCGT
AGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGAGGCCAGCCCCTGGCTCACTGG
CACAGGGCAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATGGGACGGAAGTCTGCTTGGC
AGTGGCTTTGATAAGCGATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTTCAATGCCTGCCACCCTGCC
CGAGGATGTACAGAGCCGTGCCCACACATTTCCTTGCAACTTGATCAAATTTCTTAAAGCAAACAACAAAAATGTACATTTCTGTTTTTC
CTTTTAATAAACAGGTGTACTCTTTATCATGGTTGGTATGATGGACCATTCTTTGGGGCGGAGGATTGATTATGTTACTCTCTTTAAAAT
CTGTTCCCATATTGAACAGGCAGATTGGAAAAGCTATGGTTCGATTTCTCAGAAGAAATGTTTAGGTCTTAGTCAATAGTTTTAACTATG
CCATTTGTTTAAATGAGTGCATTTGCTTCGAGGGTAGTGTCTTACTAAAAGTTAGGAACAGAGACCTAGTGGTGTGTCCAAGGCCGTGTC
ACTTTCCCCTTCAGCACACCCCAGCTTCTGACCTCAGAGCCCAGGAGCTGCGTGGACAGTGTGGGGTGCCAGGAGGAGGGGCGGTGGCTG
GTCCTCAGGCACGCTGCACTCCCAGCCAGACATGGTCTTTCCGTTTCTTAAGTAGCAAGTGTAGGTTTCAGCTGGCAGTTCCACCTGCAT
GTTCTCTGCTTCGCTGCCTTGGAAGGGGCCACATTCCCCATTCCTCTTCTCCTTACAGCGCCTGCCTCCTTTTTCAAGCAGGCGGAAAGC
TGCTGTTTCTCACGTTTCAGGGAGAGGGGTGAGCGGAGGGAGACCTGTGTCCGTGCCGTCCGGCTCCCTGGGTGGGAACAGGCAAGGGAT
CAGATGCCCCTGACACCACGCCTCTGGCCACACCAGATGCCTCTGCAGTCCTCGACAGCCTCTTCAGTGTCCCTCCTGCGGTGATGTCCT
TACTGTCCCCAGCCAGGGCCGGGGACCGGTGTTTCACTGAGGACCTGCATTAGAAACATTTTTTAAATTGTTGTACAGGAAGAGATGTGT
CTAAAACAGCATCTTAAAGCTGAGTGTATTTCTTTGCACAAGGGGTCATGCTGATGAATTCTTCTTTCATTCTGATCTTTGTTCAGCCAA
CAGGAGCGTCCTTTTCTAATGTCTTCCATTCCTACCCCCCACCCAAAAACAAAAGAAATATTTGTAGCTTGCTATCTGTATTTGAATTTT
TAGCAATTTTATATTTAGATACTTTGAAAAATGTAAATGACTAATTTGGTCATTAAATCTTGTGACATATTCGATATTAAAATGATATTA

>6240_6240_13_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000359920_MAPKAP1_chr9_128230388_ENST00000373511_length(amino acids)=385AA_BP=263
MVTVGTNILPSRPAASANTAREDAALFSRRIPPRHKNGAAQPGAAPGPGAPGANMGNAHSKSGDRHSALPGRPELSFYGSFPRKWSENVF
LDNELLTSKILSVLRPQSERGFRAGDLRYPTHFLSTNSVLASVTASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPAGPGTQL
GPITGEMDEADSAFLKFKQTADDSLSLTSPNTESIFVEDPYTASLRSEIESDGHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYGISGD
KVEIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFESDAATVNEIVLKVNYILESRASTARADY

--------------------------------------------------------------
>6240_6240_14_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000359920_MAPKAP1_chr9_128230388_ENST00000394063_length(transcript)=2904nt_BP=1049nt
AAACACCATGCCCTGCCATCTCTGGGTCTTAGAGTCACCCTAACATCTGATCTAGATTAATTATCATCATGTGCGAGGTTTTGGCATGAA
GCACGCCAGGCTCACCGTTTCATGATCTTAGACTATTTACAGCAAACTCAAACAGCTCACTTGCTTTTTACACCCTGCAAAGACCAAGGG
AGAGCCTGGAGGGGTTGTTTTTTTTTTCTGTTTTATTCTATCAAAGCAGCAAATACTGCAATTTCCACAGTAAATGGTCACAGTGGGGAC
CAATATCCTGCCCTCCAGACCCGCTGCTTCAGCCAATACAGCAAGGGAAGACGCAGCTCTGTTTTCTAGAAGGATCCCACCGAGGCATAA
AAACGGCGCAGCCCAGCCTGGCGCCGCGCCGGGTCCCGGAGCCCCGGGCGCGAACATGGGGAATGCGCACTCCAAAAGCGGGGACAGGCA
CAGCGCGCTCCCCGGCCGCCCCGAGCTGTCTTTTTACGGCTCTTTCCCCAGGAAATGGAGCGAGAACGTCTTCTTGGATAACGAGCTGCT
GACCTCCAAGATCCTGTCTGTGCTGCGGCCGCAGTCGGAGCGGGGCTTCCGCGCCGGGGACCTCCGCTACCCGACCCACTTTCTCAGCAC
CAACTCTGTCCTTGCCTCTGTCACAGCCTCGCTCAAGGAGCACCCCCGGGGCACCCTCCTGTCCGATGGCAGCCCGGCCCTGTCCAGGAA
TGTCGGTATGACGGTCTCTCAGAAAGGGGGTCCCCAGCCAACACCGAGCCCGGCTGGCCCTGGGACGCAACTCGGACCAATCACAGGAGA
GATGGATGAAGCCGATTCTGCGTTTTTAAAATTTAAGCAGACAGCTGATGACTCTCTGTCCCTTACATCTCCAAACACCGAGTCCATTTT
TGTAGAAGATCCCTACACCGCCTCGCTGAGGAGTGAGATTGAGTCAGACGGCCACGAGTTTGAAGCTGAGTCCTGGAGCCTCGCCGTGGA
TGCAGCCTACGCCAAGAAGCAAAAGAGGGAGGTGGTGAAAAGACAAGATGTCCTTTATGGTATCTCTGGAGACAAAGTAGAGATAGACCC
TGTTACGAATCAGAAAGCCAGCACTAAGTTTTGGATTAAGCAGAAACCCATCTCAATCGATTCCGACCTGCTCTGTGCCTGTGACCTTGC
TGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCACGTATCTAAGCAATCACGACTATAAACACCTCTACTTTGAATCGGACGCTGC
TACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGAGCTAGCACTGCCCGGGCTGACTACTTTGCTCAAAAACAAAG
AAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGTGACACTGGCCTCCAGCCTCAATCTGTTCCGT
AGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGAGGCCAGCCCCTGGCTCACTGG
CACAGGGCAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATGGGACGGAAGTCTGCTTGGC
AGTGGCTTTGATAAGCGATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTTCAATGCCTGCCACCCTGCC
CGAGGATGTACAGAGCCGTGCCCACACATTTCCTTGCAACTTGATCAAATTTCTTAAAGCAAACAACAAAAATGTACATTTCTGTTTTTC
CTTTTAATAAACAGGTGTACTCTTTATCATGGTTGGTATGATGGACCATTCTTTGGGGCGGAGGATTGATTATGTTACTCTCTTTAAAAT
CTGTTCCCATATTGAACAGGCAGATTGGAAAAGCTATGGTTCGATTTCTCAGAAGAAATGTTTAGGTCTTAGTCAATAGTTTTAACTATG
CCATTTGTTTAAATGAGTGCATTTGCTTCGAGGGTAGTGTCTTACTAAAAGTTAGGAACAGAGACCTAGTGGTGTGTCCAAGGCCGTGTC
ACTTTCCCCTTCAGCACACCCCAGCTTCTGACCTCAGAGCCCAGGAGCTGCGTGGACAGTGTGGGGTGCCAGGAGGAGGGGCGGTGGCTG
GTCCTCAGGCACGCTGCACTCCCAGCCAGACATGGTCTTTCCGTTTCTTAAGTAGCAAGTGTAGGTTTCAGCTGGCAGTTCCACCTGCAT
GTTCTCTGCTTCGCTGCCTTGGAAGGGGCCACATTCCCCATTCCTCTTCTCCTTACAGCGCCTGCCTCCTTTTTCAAGCAGGCGGAAAGC
TGCTGTTTCTCACGTTTCAGGGAGAGGGGTGAGCGGAGGGAGACCTGTGTCCGTGCCGTCCGGCTCCCTGGGTGGGAACAGGCAAGGGAT
CAGATGCCCCTGACACCACGCCTCTGGCCACACCAGATGCCTCTGCAGTCCTCGACAGCCTCTTCAGTGTCCCTCCTGCGGTGATGTCCT
TACTGTCCCCAGCCAGGGCCGGGGACCGGTGTTTCACTGAGGACCTGCATTAGAAACATTTTTTAAATTGTTGTACAGGAAGAGATGTGT
CTAAAACAGCATCTTAAAGCTGAGTGTATTTCTTTGCACAAGGGGTCATGCTGATGAATTCTTCTTTCATTCTGATCTTTGTTCAGCCAA
CAGGAGCGTCCTTTTCTAATGTCTTCCATTCCTACCCCCCACCCAAAAACAAAAGAAATATTTGTAGCTTGCTATCTGTATTTGAATTTT
TAGCAATTTTATATTTAGATACTTTGAAAAATGTAAATGACTAATTTGGTCATTAAATCTTGTGACATATTCGATATTAAAATGATATTA

>6240_6240_14_ARHGEF18-MAPKAP1_ARHGEF18_chr19_7506938_ENST00000359920_MAPKAP1_chr9_128230388_ENST00000394063_length(amino acids)=385AA_BP=263
MVTVGTNILPSRPAASANTAREDAALFSRRIPPRHKNGAAQPGAAPGPGAPGANMGNAHSKSGDRHSALPGRPELSFYGSFPRKWSENVF
LDNELLTSKILSVLRPQSERGFRAGDLRYPTHFLSTNSVLASVTASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPAGPGTQL
GPITGEMDEADSAFLKFKQTADDSLSLTSPNTESIFVEDPYTASLRSEIESDGHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYGISGD
KVEIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFESDAATVNEIVLKVNYILESRASTARADY

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ARHGEF18-MAPKAP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneMAPKAP1chr19:7506938chr9:128230388ENST00000265960812468_522402.3333333333333523.0ATF2
TgeneMAPKAP1chr19:7506938chr9:128230388ENST00000350766711468_522366.3333333333333487.0ATF2
TgeneMAPKAP1chr19:7506938chr9:128230388ENST00000373498711468_522402.3333333333333523.0ATF2
TgeneMAPKAP1chr19:7506938chr9:128230388ENST00000373503711468_522210.33333333333334331.0ATF2
TgeneMAPKAP1chr19:7506938chr9:128230388ENST00000373511711468_522355.3333333333333476.0ATF2
TgeneMAPKAP1chr19:7506938chr9:128230388ENST0000039406008468_5220324.0ATF2
TgeneMAPKAP1chr19:7506938chr9:128230388ENST00000394063610468_522210.33333333333334331.0ATF2
TgeneMAPKAP1chr19:7506938chr9:128230388ENST00000394060082_1840324.0MAP3K2
TgeneMAPKAP1chr19:7506938chr9:128230388ENST00000394060082_2670324.0NBN


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneMAPKAP1chr19:7506938chr9:128230388ENST000002659608122_184402.3333333333333523.0MAP3K2
TgeneMAPKAP1chr19:7506938chr9:128230388ENST000003507667112_184366.3333333333333487.0MAP3K2
TgeneMAPKAP1chr19:7506938chr9:128230388ENST000003734987112_184402.3333333333333523.0MAP3K2
TgeneMAPKAP1chr19:7506938chr9:128230388ENST000003735037112_184210.33333333333334331.0MAP3K2
TgeneMAPKAP1chr19:7506938chr9:128230388ENST000003735117112_184355.3333333333333476.0MAP3K2
TgeneMAPKAP1chr19:7506938chr9:128230388ENST000003940636102_184210.33333333333334331.0MAP3K2
TgeneMAPKAP1chr19:7506938chr9:128230388ENST000002659608122_267402.3333333333333523.0NBN
TgeneMAPKAP1chr19:7506938chr9:128230388ENST000003507667112_267366.3333333333333487.0NBN
TgeneMAPKAP1chr19:7506938chr9:128230388ENST000003734987112_267402.3333333333333523.0NBN
TgeneMAPKAP1chr19:7506938chr9:128230388ENST000003735037112_267210.33333333333334331.0NBN
TgeneMAPKAP1chr19:7506938chr9:128230388ENST000003735117112_267355.3333333333333476.0NBN
TgeneMAPKAP1chr19:7506938chr9:128230388ENST000003940636102_267210.33333333333334331.0NBN


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ARHGEF18-MAPKAP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ARHGEF18-MAPKAP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneARHGEF18C0035334Retinitis Pigmentosa1ORPHANET
HgeneARHGEF18C4479481RETINITIS PIGMENTOSA 781CTD_human;GENOMICS_ENGLAND;UNIPROT