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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CABIN1-MIF (FusionGDB2 ID:HG23523TG4282)

Fusion Gene Summary for CABIN1-MIF

check button Fusion gene summary
Fusion gene informationFusion gene name: CABIN1-MIF
Fusion gene ID: hg23523tg4282
HgeneTgene
Gene symbol

CABIN1

MIF

Gene ID

23523

4282

Gene namecalcineurin binding protein 1macrophage migration inhibitory factor
SynonymsCAIN|KB-318B8.7|PPP3INGIF|GLIF|MMIF
Cytomap('CABIN1')('MIF')

22q11.23

22q11.23

Type of geneprotein-codingprotein-coding
Descriptioncalcineurin-binding protein cabin-1calcineurin binding protein cabin 1calcineurin inhibitormacrophage migration inhibitory factorL-dopachrome isomeraseL-dopachrome tautomeraseepididymis secretory sperm binding proteinmacrophage migration inhibitory factor (glycosylation-inhibiting factor)phenylpyruvate tautomerase
Modification date2020031320200322
UniProtAcc

Q9Y6J0

.
Ensembl transtripts involved in fusion geneENST00000263119, ENST00000398319, 
ENST00000405822, ENST00000337989, 
ENST00000485008, 
Fusion gene scores* DoF score16 X 15 X 8=19206 X 4 X 5=120
# samples 1810
** MAII scorelog2(18/1920*10)=-3.41503749927884
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/120*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CABIN1 [Title/Abstract] AND MIF [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCABIN1(24530382)-MIF(24236958), # samples:1
CABIN1(24451622)-MIF(24236959), # samples:1
CABIN1(24447436)-MIF(24236959), # samples:1
CABIN1(24530382)-MIF(24236959), # samples:1
Anticipated loss of major functional domain due to fusion event.CABIN1-MIF seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CABIN1-MIF seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CABIN1-MIF seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CABIN1-MIF seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCABIN1

GO:0006336

DNA replication-independent nucleosome assembly

14718166

TgeneMIF

GO:0001516

prostaglandin biosynthetic process

12782713

TgeneMIF

GO:0007166

cell surface receptor signaling pathway

12782713

TgeneMIF

GO:0010629

negative regulation of gene expression

10562313

TgeneMIF

GO:0010739

positive regulation of protein kinase A signaling

17045821

TgeneMIF

GO:0010760

negative regulation of macrophage chemotaxis

21817065

TgeneMIF

GO:0019752

carboxylic acid metabolic process

12782713

TgeneMIF

GO:0030890

positive regulation of B cell proliferation

12782713

TgeneMIF

GO:0032760

positive regulation of tumor necrosis factor production

21817065

TgeneMIF

GO:0033138

positive regulation of peptidyl-serine phosphorylation

17045821

TgeneMIF

GO:0042327

positive regulation of phosphorylation

12782713

TgeneMIF

GO:0043066

negative regulation of apoptotic process

12782713

TgeneMIF

GO:0043518

negative regulation of DNA damage response, signal transduction by p53 class mediator

17045821

TgeneMIF

GO:0048146

positive regulation of fibroblast proliferation

12782713

TgeneMIF

GO:0050715

positive regulation of cytokine secretion

19602265

TgeneMIF

GO:0050731

positive regulation of peptidyl-tyrosine phosphorylation

17045821

TgeneMIF

GO:0070374

positive regulation of ERK1 and ERK2 cascade

12782713|17045821

TgeneMIF

GO:0071157

negative regulation of cell cycle arrest

10562313

TgeneMIF

GO:0090344

negative regulation of cell aging

10562313

TgeneMIF

GO:1902166

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

17045821


check buttonFusion gene breakpoints across CABIN1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across MIF (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ACCTCGA-OR-A5JA-01ACABIN1chr22

24447436

+MIFchr22

24236959

+
ChimerDB4ACCTCGA-OR-A5JA-01ACABIN1chr22

24451622

+MIFchr22

24236959

+
ChimerDB4OVTCGA-24-1551-01ACABIN1chr22

24530382

+MIFchr22

24236959

+
ChimerDB4OVTCGA-24-1551CABIN1chr22

24530382

+MIFchr22

24236958

+


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Fusion Gene ORF analysis for CABIN1-MIF

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000263119ENST00000215754CABIN1chr22

24447436

+MIFchr22

24236959

+
Frame-shiftENST00000263119ENST00000215754CABIN1chr22

24451622

+MIFchr22

24236959

+
Frame-shiftENST00000398319ENST00000215754CABIN1chr22

24447436

+MIFchr22

24236959

+
Frame-shiftENST00000398319ENST00000215754CABIN1chr22

24451622

+MIFchr22

24236959

+
Frame-shiftENST00000405822ENST00000215754CABIN1chr22

24451622

+MIFchr22

24236959

+
In-frameENST00000263119ENST00000215754CABIN1chr22

24530382

+MIFchr22

24236959

+
In-frameENST00000263119ENST00000215754CABIN1chr22

24530382

+MIFchr22

24236958

+
In-frameENST00000398319ENST00000215754CABIN1chr22

24530382

+MIFchr22

24236959

+
In-frameENST00000398319ENST00000215754CABIN1chr22

24530382

+MIFchr22

24236958

+
In-frameENST00000405822ENST00000215754CABIN1chr22

24530382

+MIFchr22

24236959

+
In-frameENST00000405822ENST00000215754CABIN1chr22

24530382

+MIFchr22

24236958

+
intron-3CDSENST00000337989ENST00000215754CABIN1chr22

24447436

+MIFchr22

24236959

+
intron-3CDSENST00000337989ENST00000215754CABIN1chr22

24451622

+MIFchr22

24236959

+
intron-3CDSENST00000337989ENST00000215754CABIN1chr22

24530382

+MIFchr22

24236959

+
intron-3CDSENST00000337989ENST00000215754CABIN1chr22

24530382

+MIFchr22

24236958

+
intron-3CDSENST00000405822ENST00000215754CABIN1chr22

24447436

+MIFchr22

24236959

+
intron-3CDSENST00000485008ENST00000215754CABIN1chr22

24447436

+MIFchr22

24236959

+
intron-3CDSENST00000485008ENST00000215754CABIN1chr22

24451622

+MIFchr22

24236959

+
intron-3CDSENST00000485008ENST00000215754CABIN1chr22

24530382

+MIFchr22

24236959

+
intron-3CDSENST00000485008ENST00000215754CABIN1chr22

24530382

+MIFchr22

24236958

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000263119CABIN1chr2224530382+ENST00000215754MIFchr2224236958+5233487312151121663
ENST00000405822CABIN1chr2224530382+ENST00000215754MIFchr2224236958+496346038848421584
ENST00000398319CABIN1chr2224530382+ENST00000215754MIFchr2224236958+5491513137953701663
ENST00000263119CABIN1chr2224530382+ENST00000215754MIFchr2224236959+5233487312151121663
ENST00000405822CABIN1chr2224530382+ENST00000215754MIFchr2224236959+496346038848421584
ENST00000398319CABIN1chr2224530382+ENST00000215754MIFchr2224236959+5491513137953701663

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000263119ENST00000215754CABIN1chr2224530382+MIFchr2224236958+0.00750250.9924975
ENST00000405822ENST00000215754CABIN1chr2224530382+MIFchr2224236958+0.0052303230.99476963
ENST00000398319ENST00000215754CABIN1chr2224530382+MIFchr2224236958+0.0091578590.9908421
ENST00000263119ENST00000215754CABIN1chr2224530382+MIFchr2224236959+0.00750250.9924975
ENST00000405822ENST00000215754CABIN1chr2224530382+MIFchr2224236959+0.0052303230.99476963
ENST00000398319ENST00000215754CABIN1chr2224530382+MIFchr2224236959+0.0091578590.9908421

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Fusion Genomic Features for CABIN1-MIF


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CABIN1chr2224451622+MIFchr2224236958+0.0008847180.9991153
CABIN1chr2224447436+MIFchr2224236958+0.0008344420.99916553
CABIN1chr2224530382+MIFchr2224236958+0.0004773270.9995227
CABIN1chr2224530382+MIFchr2224236958+0.0004773270.9995227
CABIN1chr2224451622+MIFchr2224236958+0.0008847180.9991153
CABIN1chr2224447436+MIFchr2224236958+0.0008344420.99916553
CABIN1chr2224530382+MIFchr2224236958+0.0004773270.9995227
CABIN1chr2224530382+MIFchr2224236958+0.0004773270.9995227

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CABIN1-MIF


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:24530382/chr22:24236958)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CABIN1

Q9Y6J0

.
FUNCTION: May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it's target genes. {ECO:0000269|PubMed:14718166, ECO:0000269|PubMed:9655484}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCABIN1chr22:24530382chr22:24236958ENST00000263119+29371055_108815822221.0RepeatNote=TPR 5
HgeneCABIN1chr22:24530382chr22:24236958ENST00000263119+29371106_113915822221.0RepeatNote=TPR 6
HgeneCABIN1chr22:24530382chr22:24236958ENST00000263119+2937125_15715822221.0RepeatNote=TPR 3
HgeneCABIN1chr22:24530382chr22:24236958ENST00000263119+293736_6915822221.0RepeatNote=TPR 1
HgeneCABIN1chr22:24530382chr22:24236958ENST00000263119+2937615_64815822221.0RepeatNote=TPR 4
HgeneCABIN1chr22:24530382chr22:24236958ENST00000263119+293790_12315822221.0RepeatNote=TPR 2
HgeneCABIN1chr22:24530382chr22:24236958ENST00000398319+29371055_108815822221.0RepeatNote=TPR 5
HgeneCABIN1chr22:24530382chr22:24236958ENST00000398319+29371106_113915822221.0RepeatNote=TPR 6
HgeneCABIN1chr22:24530382chr22:24236958ENST00000398319+2937125_15715822221.0RepeatNote=TPR 3
HgeneCABIN1chr22:24530382chr22:24236958ENST00000398319+293736_6915822221.0RepeatNote=TPR 1
HgeneCABIN1chr22:24530382chr22:24236958ENST00000398319+2937615_64815822221.0RepeatNote=TPR 4
HgeneCABIN1chr22:24530382chr22:24236958ENST00000398319+293790_12315822221.0RepeatNote=TPR 2
HgeneCABIN1chr22:24530382chr22:24236959ENST00000263119+29371055_108815822221.0RepeatNote=TPR 5
HgeneCABIN1chr22:24530382chr22:24236959ENST00000263119+29371106_113915822221.0RepeatNote=TPR 6
HgeneCABIN1chr22:24530382chr22:24236959ENST00000263119+2937125_15715822221.0RepeatNote=TPR 3
HgeneCABIN1chr22:24530382chr22:24236959ENST00000263119+293736_6915822221.0RepeatNote=TPR 1
HgeneCABIN1chr22:24530382chr22:24236959ENST00000263119+2937615_64815822221.0RepeatNote=TPR 4
HgeneCABIN1chr22:24530382chr22:24236959ENST00000263119+293790_12315822221.0RepeatNote=TPR 2
HgeneCABIN1chr22:24530382chr22:24236959ENST00000398319+29371055_108815822221.0RepeatNote=TPR 5
HgeneCABIN1chr22:24530382chr22:24236959ENST00000398319+29371106_113915822221.0RepeatNote=TPR 6
HgeneCABIN1chr22:24530382chr22:24236959ENST00000398319+2937125_15715822221.0RepeatNote=TPR 3
HgeneCABIN1chr22:24530382chr22:24236959ENST00000398319+293736_6915822221.0RepeatNote=TPR 1
HgeneCABIN1chr22:24530382chr22:24236959ENST00000398319+2937615_64815822221.0RepeatNote=TPR 4
HgeneCABIN1chr22:24530382chr22:24236959ENST00000398319+293790_12315822221.0RepeatNote=TPR 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for CABIN1-MIF


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>12236_12236_1_CABIN1-MIF_CABIN1_chr22_24530382_ENST00000263119_MIF_chr22_24236958_ENST00000215754_length(transcript)=5233nt_BP=4873nt
AGCCGGACGGCGCGGTGGTCGGGACAGACTGGCCGTTGCTGTGGAGACGCCTGGAGAGTTGTGGACTGGGGCAACCTTTGCCAGTGATGA
GAAGTGATGCTCGTGGCAGTGCTGAATCTCTCTGAATATGATTCGAATTGCAGCCTTAAATGCCAGCTCCACCATTGAGGATGATCATGA
AGGAAGCTTTAAAAGTCACAAAACCCAGACAAAGGAGGCTCAGGAAGCAGAGGCTTTTGCATTGTACCACAAGGCCCTTGATCTGCAGAA
ACATGACCGGTTTGAGGAGTCTGCCAAAGCCTACCATGAGCTCTTGGAGGCGAGCCTGCTGCGGGAGGCAGTTTCATCCGGTGATGAGAA
AGAGGGGTTGAAACACCCTGGGCTGATACTGAAATATTCCACTTATAAGAACTTGGCCCAGCTGGCAGCCCAGCGGGAGGATCTGGAGAC
AGCCATGGAGTTCTACTTAGAGGCAGTGATGCTGGACTCCACAGATGTCAACCTCTGGTATAAGATTGGACATGTGGCCCTGAGGCTCAT
CCGGATCCCCCTGGCTCGCCATGCTTTTGAGGAAGGGCTGCGGTGCAATCCTGACCACTGGCCCTGTTTGGATAACCTAATCACTGTCCT
GTACACCCTCAGTGATTACACAACATGTCTGTACTTCATCTGCAAAGCTTTGGAGAAGGATTGCCGGTACAGCAAAGGGCTGGTCCTCAA
GGAGAAGATTTTTGAGGAGCAGCCTTGTCTCCGGAAGGACTCTCTCAGAATGTTCCTCAAATGTGACATGTCGATTCACGATGTTTCGGT
GAGTGCAGCTGAGACACAGGCGATTGTAGATGAGGCCTTGGGGCTGCGAAAAAAGAGGCAAGCGCTGATTGTGCGGGAGAAGGAGCCGGA
CCTGAAACTTGTGCAGCCCATTCCTTTCTTCACCTGGAAGTGCCTCGGAGAGAGCTTGCTGGCCATGTACAATCATCTCACCACCTGTGA
GCCCCCACGTCCCAGCCTTGGCAAAAGGATTGATTTGTCGGACTACCAGGACCCCAGCCAGCCTCTTGAGTCCTCCATGGTGGTGACGCC
AGTTAACGTGATCCAGCCAAGCACTGTCAGCACCAACCCAGCTGTGGCTGTCGCCGAGCCTGTGGTCTCCTACACCTCTGTGGCTACAAC
CAGCTTCCCACTGCACAGTCCTGGTCTGTTGGAGACAGGCGCTCCTGTGGGTGATATTTCTGGGGGAGATAAATCCAAGAAAGGGGTAAA
ACGGAAGAAGATTTCAGAAGAGAGTGGAGAAACAGCAAAGCGGCGGTCTGCCCGTGTCCGAAACACCAAGTGCAAAAAAGAAGAGAAAGT
AGACTTCCAGGAGCTTCTGATGAAGTTCTTGCCGTCCAGGTTAAGAAAGCTGGACCCTGAGGAGGAAGATGATTCCTTTAATAACTATGA
AGTCCAGTCAGAAGCCAAACTGGAAAGCTTCCCAAGCATTGGGCCTCAAAGGCTGTCATTTGACTCAGCCACATTCATGGAATCTGAAAA
GCAGGACGTGCATGAGTTCCTGCTGGAGAACCTAACCAACGGGGGCATCCTGGAGCTGATGATGCGCTACCTGAAAGCCATGGGCCACAA
GTTCTTGGTAAGGTGGCCTCCAGGCTTGGCGGAGGTCGTGCTCAGCGTCTACCACAGCTGGAGGAGGCACAGCACCAGCCTGCCCAACCC
GCTGCTGAGGGACTGCAGCAACAAGCACATCAAGGACATGATGCTGATGTCTCTCTCCTGCATGGAACTCCAGCTGGACCAGTGGCTGCT
GACCAAAGGCAGAAGCTCTGCAGTGTCTCCTCGGAACTGTCCTGCTGGTATGGTGAATGGCAGATTTGGACCTGACTTCCCAGGGACCCA
CTGCCTGGGTGACCTCCTACAGCTGTCATTTGCCTCGTCCCAGCGCGACCTGTTCGAGGATGGTTGGCTGGAGTTTGTGGTCCGTGTTTA
CTGGCTGAAGGCTCGCTTCCTGGCGCTGCAGGGAGACATGGAGCAGGCCCTGGAGAACTATGACATCTGCACAGAAATGCTCCAGAGTTC
CACCGCCATCCAGGTGGAGGCAGGGGCTGAACGAAGAGACATTGTCATCCGGCTGCCCAACCTCCATAATGACTCTGTGGTTTCCCTGGA
GGAGATTGATAAGAACCTGAAGTCGCTGGAGCGGTGCCAGTCCCTGGAGGAGATTCAGCGGCTGTATGAAGCAGGCGACTACAAGGCTGT
TGTGCATCTGCTCCGCCCCACTTTGTGCACCAGTGGGTTTGACCGGGCCAAACACCTGGAGTTTATGACTTCCATTCCTGAGAGGCCAGC
CCAGCTGCTTCTTCTGCAGGACTCCTTGCTCCGGCTGAAGGACTATCGGCAGTGTTTTGAGTGTTCCGATGTGGCTCTGAACGAGGCTGT
CCAGCAGATGGTGAACTCAGGTGAGGCTGCCGCCAAGGAGGAGTGGGTGGCCACAGTGACCCAACTGCTGATGGGCATCGAGCAGGCCCT
CTCTGCGGACAGCAGTGGTAGCATCCTGAAGGTATCATCCTCCACCACTGGCCTTGTGCGGCTCACCAACAACCTCATCCAGGTCATTGA
CTGCAGCATGGCTGTGCAGGAGGAGGCCAAGGAGCCCCACGTCTCTTCAGTGCTACCCTGGATCATTCTACACCGGATCATCTGGCAGGA
GGAAGACACCTTCCATTCTCTGTGCCACCAGCAGCAGCTCCAAAACCCAGCGGAGGAAGGGATGTCAGAGACGCCCATGCTCCCATCCTC
CCTCATGCTGCTGAACACAGCCCACGAGTATTTGGGCAGAAGGTCCTGGTGCTGCAATTCAGATGGGGCTCTGCTGCGATTCTATGTGCG
AGTACTCCAGAAGGAACTGGCTGCATCCACCTCTGAAGACACGCACCCTTACAAGGAGGAGCTGGAGACAGCCTTGGAGCAGTGCTTCTA
CTGCCTGTACAGCTTCCCCAGCAAGAAGAGTAAGGCCAGGTACCTGGAGGAACACTCGGCCCAGCAGGTGGATCTTATATGGGAGGATGC
ACTGTTCATGTTTGAGTATTTTAAGCCCAAGACCCTTCCTGAATTTGACAGCTATAAGACCAGCACCGTGTCTGCTGACTTGGCCAACCT
ACTGAAGAGAATTGCCACCATTGTGCCTCGCACAGAGAGGCCAGCCCTTAGCCTGGACAAAGTCTCTGCCTACATTGAGGGAACTTCAAC
TGAGGTACCCTGCCTCCCAGAGGGGGCTGACCCCTCCCCTCCAGTGGTGAACGAGCTTTACTACCTCCTGGCTGATTATCATTTCAAAAA
CAAGGAGCAGTCCAAGGCCATCAAGTTCTACATGCATGACATCTGCATCTGCCCCAATAGGTTTGATTCCTGGGCAGGCATGGCTCTGGC
CCGGGCCAGCCGCATTCAGGACAAGCTGAACTCCAATGAGCTGAAGAGTGATGGGCCCATTTGGAAGCATGCCACGCCCGTCTTGAACTG
CTTCCGTCGGGCCCTGGAGATTGACAGCTCCAACTTGTCCCTATGGATTGAGTATGGCACCATGTCCTATGCCTTGCACTCATTCGCCTC
ACGTCAATTGAAGCAGTGGAGAGGCGAGCTGCCCCCTGAGCTCGTGCAGCAGATGGAGGGCCGGCGCGACAGCATGCTAGAGACAGCCAA
GCACTGTTTCACATCAGCAGCCCGCTGCGAGGGTGATGGTGACGAGGAGGAGTGGCTCATCCACTACATGCTGGGCAAGGTGGCTGAGAA
GCAGCAGCAGCCACCCACCGTTTACTTGCTGCACTACAGGCAGGCTGGCCACTACCTGCACGAGGAGGCTGCCCGCTACCCCAAGAAGAT
CCACTACCACAACCCACCTGAGCTGGCCATGGAGGCCCTGGAGGTGTACTTTCGGCTCCATGCTTCCATCCTGAAGCTCCTGGGGAAGCC
CGATTCTGGGGTTGGTGCAGAGGTCCTGGTCAACTTTATGAAGGAGGCTGCAGAAGGACCCTTTGCCAGGGGCGAGGAGAAGAACACACC
CAAAGCTTCAGAAAAGGAGAAGGCCTGCCTGGTGGACGAGGACTCCCACTCTTCAGCTGGGACACTGCCGGGCCCCGGAGCCTCCCTCCC
CTCCTCCTCTGGCCCAGGTCTGACATCCCCACCTTACACAGCCACTCCGATTGACCACGATTACGTCAAATGTAAAAAACCCCACCAGCA
GGCAACGCCGGACGACCGAAGCCAGGACAGCACAGCCGTAGCACTCTCAGACTCTAGCTCAACGCAGGACTTCTTTAATGAGCCCACCAG
CTTACTGGAAGGCTCCAGGAAATCCTACACAGAGAAGAGGCTGCCCATTCTCAGTTCCCAAGCAGGAGCGACGGGTAAAGATCTTCAGGG
GGCCACAGAAGAAAGAGGAAAAAACGAGGAGTCATTGGAGAGTACAGAAGGCTTCCGGGCTGCAGAGCAAGGTGTCCAGAAGCCTGCTGC
AGAAACCCCAGCCTCTGCTTGCATCCCTGGCAAGCCCTCAGCATCCACACCCACCCTGTGGGATGGGAAGAAGAGAGGGGACCTCCCAGG
GGAGCCAGTGGCCTTCCCCCAGGGGCTGCCGGCTGGTGCTGAGGAGCAGCGGCAGTTTCTCACAGAGCAGTGCATCGCCTCCTTCCGCCT
GTGCCTGAGCCGCTTCCCCCAGCACTATAAGAGTCTCTACCGTCTGGCCTTCCTCTACACCTACAGCAAGACCCACCGGAACCTCCAGTG
GGCCCGCGACGTGTTGCTAGGCAGCAGTATCCCGTGGCAACAACTGCAGCACATGCCGGCACAGGGGCTCTTCTGCGAGAGGAACAAGAC
CAATTTCTTCAACTACATCGCGGTGCACGTGGTCCCGGACCAGCTCATGGCCTTCGGCGGCTCCAGCGAGCCGTGCGCGCTCTGCAGCCT
GCACAGCATCGGCAAGATCGGCGGCGCGCAGAACCGCTCCTACAGCAAGCTGCTGTGCGGCCTGCTGGCCGAGCGCCTGCGCATCAGCCC
GGACAGGGTCTACATCAACTATTACGACATGAACGCGGCCAATGTGGGCTGGAACAACTCCACCTTCGCCTAAGAGCCGCAGGGACCCAC
GCTGTCTGCGCTGGCTCCACCCGGGAACCCGCCGCACGCTGTGTTCTAGGCCCGCCCACCCCAACCTTCTGGTGGGGAGAAATAAACGGT
TTAGAGACTAGGA

>12236_12236_1_CABIN1-MIF_CABIN1_chr22_24530382_ENST00000263119_MIF_chr22_24236958_ENST00000215754_length(amino acids)=1663AA_BP=1584
MNMIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLIL
KYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCL
YFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFF
TWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLL
ETGAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPSRLRKLDPEEEDDSFNNYEVQSEAKLESF
PSIGPQRLSFDSATFMESEKQDVHEFLLENLTNGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHI
KDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQ
GDMEQALENYDICTEMLQSSTAIQVEAGAERRDIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCT
SGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAKEEWVATVTQLLMGIEQALSADSSGSILK
VSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEPHVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEY
LGRRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPK
TLPEFDSYKTSTVSADLANLLKRIATIVPRTERPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFY
MHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRGEL
PPELVQQMEGRRDSMLETAKHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAM
EALEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPGLTSP
PYTATPIDHDYVKCKKPHQQATPDDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEE
SLESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAGAEEQRQFLTEQCIASFRLCLSRFPQHYK
SLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQ
NRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA

--------------------------------------------------------------
>12236_12236_2_CABIN1-MIF_CABIN1_chr22_24530382_ENST00000263119_MIF_chr22_24236959_ENST00000215754_length(transcript)=5233nt_BP=4873nt
AGCCGGACGGCGCGGTGGTCGGGACAGACTGGCCGTTGCTGTGGAGACGCCTGGAGAGTTGTGGACTGGGGCAACCTTTGCCAGTGATGA
GAAGTGATGCTCGTGGCAGTGCTGAATCTCTCTGAATATGATTCGAATTGCAGCCTTAAATGCCAGCTCCACCATTGAGGATGATCATGA
AGGAAGCTTTAAAAGTCACAAAACCCAGACAAAGGAGGCTCAGGAAGCAGAGGCTTTTGCATTGTACCACAAGGCCCTTGATCTGCAGAA
ACATGACCGGTTTGAGGAGTCTGCCAAAGCCTACCATGAGCTCTTGGAGGCGAGCCTGCTGCGGGAGGCAGTTTCATCCGGTGATGAGAA
AGAGGGGTTGAAACACCCTGGGCTGATACTGAAATATTCCACTTATAAGAACTTGGCCCAGCTGGCAGCCCAGCGGGAGGATCTGGAGAC
AGCCATGGAGTTCTACTTAGAGGCAGTGATGCTGGACTCCACAGATGTCAACCTCTGGTATAAGATTGGACATGTGGCCCTGAGGCTCAT
CCGGATCCCCCTGGCTCGCCATGCTTTTGAGGAAGGGCTGCGGTGCAATCCTGACCACTGGCCCTGTTTGGATAACCTAATCACTGTCCT
GTACACCCTCAGTGATTACACAACATGTCTGTACTTCATCTGCAAAGCTTTGGAGAAGGATTGCCGGTACAGCAAAGGGCTGGTCCTCAA
GGAGAAGATTTTTGAGGAGCAGCCTTGTCTCCGGAAGGACTCTCTCAGAATGTTCCTCAAATGTGACATGTCGATTCACGATGTTTCGGT
GAGTGCAGCTGAGACACAGGCGATTGTAGATGAGGCCTTGGGGCTGCGAAAAAAGAGGCAAGCGCTGATTGTGCGGGAGAAGGAGCCGGA
CCTGAAACTTGTGCAGCCCATTCCTTTCTTCACCTGGAAGTGCCTCGGAGAGAGCTTGCTGGCCATGTACAATCATCTCACCACCTGTGA
GCCCCCACGTCCCAGCCTTGGCAAAAGGATTGATTTGTCGGACTACCAGGACCCCAGCCAGCCTCTTGAGTCCTCCATGGTGGTGACGCC
AGTTAACGTGATCCAGCCAAGCACTGTCAGCACCAACCCAGCTGTGGCTGTCGCCGAGCCTGTGGTCTCCTACACCTCTGTGGCTACAAC
CAGCTTCCCACTGCACAGTCCTGGTCTGTTGGAGACAGGCGCTCCTGTGGGTGATATTTCTGGGGGAGATAAATCCAAGAAAGGGGTAAA
ACGGAAGAAGATTTCAGAAGAGAGTGGAGAAACAGCAAAGCGGCGGTCTGCCCGTGTCCGAAACACCAAGTGCAAAAAAGAAGAGAAAGT
AGACTTCCAGGAGCTTCTGATGAAGTTCTTGCCGTCCAGGTTAAGAAAGCTGGACCCTGAGGAGGAAGATGATTCCTTTAATAACTATGA
AGTCCAGTCAGAAGCCAAACTGGAAAGCTTCCCAAGCATTGGGCCTCAAAGGCTGTCATTTGACTCAGCCACATTCATGGAATCTGAAAA
GCAGGACGTGCATGAGTTCCTGCTGGAGAACCTAACCAACGGGGGCATCCTGGAGCTGATGATGCGCTACCTGAAAGCCATGGGCCACAA
GTTCTTGGTAAGGTGGCCTCCAGGCTTGGCGGAGGTCGTGCTCAGCGTCTACCACAGCTGGAGGAGGCACAGCACCAGCCTGCCCAACCC
GCTGCTGAGGGACTGCAGCAACAAGCACATCAAGGACATGATGCTGATGTCTCTCTCCTGCATGGAACTCCAGCTGGACCAGTGGCTGCT
GACCAAAGGCAGAAGCTCTGCAGTGTCTCCTCGGAACTGTCCTGCTGGTATGGTGAATGGCAGATTTGGACCTGACTTCCCAGGGACCCA
CTGCCTGGGTGACCTCCTACAGCTGTCATTTGCCTCGTCCCAGCGCGACCTGTTCGAGGATGGTTGGCTGGAGTTTGTGGTCCGTGTTTA
CTGGCTGAAGGCTCGCTTCCTGGCGCTGCAGGGAGACATGGAGCAGGCCCTGGAGAACTATGACATCTGCACAGAAATGCTCCAGAGTTC
CACCGCCATCCAGGTGGAGGCAGGGGCTGAACGAAGAGACATTGTCATCCGGCTGCCCAACCTCCATAATGACTCTGTGGTTTCCCTGGA
GGAGATTGATAAGAACCTGAAGTCGCTGGAGCGGTGCCAGTCCCTGGAGGAGATTCAGCGGCTGTATGAAGCAGGCGACTACAAGGCTGT
TGTGCATCTGCTCCGCCCCACTTTGTGCACCAGTGGGTTTGACCGGGCCAAACACCTGGAGTTTATGACTTCCATTCCTGAGAGGCCAGC
CCAGCTGCTTCTTCTGCAGGACTCCTTGCTCCGGCTGAAGGACTATCGGCAGTGTTTTGAGTGTTCCGATGTGGCTCTGAACGAGGCTGT
CCAGCAGATGGTGAACTCAGGTGAGGCTGCCGCCAAGGAGGAGTGGGTGGCCACAGTGACCCAACTGCTGATGGGCATCGAGCAGGCCCT
CTCTGCGGACAGCAGTGGTAGCATCCTGAAGGTATCATCCTCCACCACTGGCCTTGTGCGGCTCACCAACAACCTCATCCAGGTCATTGA
CTGCAGCATGGCTGTGCAGGAGGAGGCCAAGGAGCCCCACGTCTCTTCAGTGCTACCCTGGATCATTCTACACCGGATCATCTGGCAGGA
GGAAGACACCTTCCATTCTCTGTGCCACCAGCAGCAGCTCCAAAACCCAGCGGAGGAAGGGATGTCAGAGACGCCCATGCTCCCATCCTC
CCTCATGCTGCTGAACACAGCCCACGAGTATTTGGGCAGAAGGTCCTGGTGCTGCAATTCAGATGGGGCTCTGCTGCGATTCTATGTGCG
AGTACTCCAGAAGGAACTGGCTGCATCCACCTCTGAAGACACGCACCCTTACAAGGAGGAGCTGGAGACAGCCTTGGAGCAGTGCTTCTA
CTGCCTGTACAGCTTCCCCAGCAAGAAGAGTAAGGCCAGGTACCTGGAGGAACACTCGGCCCAGCAGGTGGATCTTATATGGGAGGATGC
ACTGTTCATGTTTGAGTATTTTAAGCCCAAGACCCTTCCTGAATTTGACAGCTATAAGACCAGCACCGTGTCTGCTGACTTGGCCAACCT
ACTGAAGAGAATTGCCACCATTGTGCCTCGCACAGAGAGGCCAGCCCTTAGCCTGGACAAAGTCTCTGCCTACATTGAGGGAACTTCAAC
TGAGGTACCCTGCCTCCCAGAGGGGGCTGACCCCTCCCCTCCAGTGGTGAACGAGCTTTACTACCTCCTGGCTGATTATCATTTCAAAAA
CAAGGAGCAGTCCAAGGCCATCAAGTTCTACATGCATGACATCTGCATCTGCCCCAATAGGTTTGATTCCTGGGCAGGCATGGCTCTGGC
CCGGGCCAGCCGCATTCAGGACAAGCTGAACTCCAATGAGCTGAAGAGTGATGGGCCCATTTGGAAGCATGCCACGCCCGTCTTGAACTG
CTTCCGTCGGGCCCTGGAGATTGACAGCTCCAACTTGTCCCTATGGATTGAGTATGGCACCATGTCCTATGCCTTGCACTCATTCGCCTC
ACGTCAATTGAAGCAGTGGAGAGGCGAGCTGCCCCCTGAGCTCGTGCAGCAGATGGAGGGCCGGCGCGACAGCATGCTAGAGACAGCCAA
GCACTGTTTCACATCAGCAGCCCGCTGCGAGGGTGATGGTGACGAGGAGGAGTGGCTCATCCACTACATGCTGGGCAAGGTGGCTGAGAA
GCAGCAGCAGCCACCCACCGTTTACTTGCTGCACTACAGGCAGGCTGGCCACTACCTGCACGAGGAGGCTGCCCGCTACCCCAAGAAGAT
CCACTACCACAACCCACCTGAGCTGGCCATGGAGGCCCTGGAGGTGTACTTTCGGCTCCATGCTTCCATCCTGAAGCTCCTGGGGAAGCC
CGATTCTGGGGTTGGTGCAGAGGTCCTGGTCAACTTTATGAAGGAGGCTGCAGAAGGACCCTTTGCCAGGGGCGAGGAGAAGAACACACC
CAAAGCTTCAGAAAAGGAGAAGGCCTGCCTGGTGGACGAGGACTCCCACTCTTCAGCTGGGACACTGCCGGGCCCCGGAGCCTCCCTCCC
CTCCTCCTCTGGCCCAGGTCTGACATCCCCACCTTACACAGCCACTCCGATTGACCACGATTACGTCAAATGTAAAAAACCCCACCAGCA
GGCAACGCCGGACGACCGAAGCCAGGACAGCACAGCCGTAGCACTCTCAGACTCTAGCTCAACGCAGGACTTCTTTAATGAGCCCACCAG
CTTACTGGAAGGCTCCAGGAAATCCTACACAGAGAAGAGGCTGCCCATTCTCAGTTCCCAAGCAGGAGCGACGGGTAAAGATCTTCAGGG
GGCCACAGAAGAAAGAGGAAAAAACGAGGAGTCATTGGAGAGTACAGAAGGCTTCCGGGCTGCAGAGCAAGGTGTCCAGAAGCCTGCTGC
AGAAACCCCAGCCTCTGCTTGCATCCCTGGCAAGCCCTCAGCATCCACACCCACCCTGTGGGATGGGAAGAAGAGAGGGGACCTCCCAGG
GGAGCCAGTGGCCTTCCCCCAGGGGCTGCCGGCTGGTGCTGAGGAGCAGCGGCAGTTTCTCACAGAGCAGTGCATCGCCTCCTTCCGCCT
GTGCCTGAGCCGCTTCCCCCAGCACTATAAGAGTCTCTACCGTCTGGCCTTCCTCTACACCTACAGCAAGACCCACCGGAACCTCCAGTG
GGCCCGCGACGTGTTGCTAGGCAGCAGTATCCCGTGGCAACAACTGCAGCACATGCCGGCACAGGGGCTCTTCTGCGAGAGGAACAAGAC
CAATTTCTTCAACTACATCGCGGTGCACGTGGTCCCGGACCAGCTCATGGCCTTCGGCGGCTCCAGCGAGCCGTGCGCGCTCTGCAGCCT
GCACAGCATCGGCAAGATCGGCGGCGCGCAGAACCGCTCCTACAGCAAGCTGCTGTGCGGCCTGCTGGCCGAGCGCCTGCGCATCAGCCC
GGACAGGGTCTACATCAACTATTACGACATGAACGCGGCCAATGTGGGCTGGAACAACTCCACCTTCGCCTAAGAGCCGCAGGGACCCAC
GCTGTCTGCGCTGGCTCCACCCGGGAACCCGCCGCACGCTGTGTTCTAGGCCCGCCCACCCCAACCTTCTGGTGGGGAGAAATAAACGGT
TTAGAGACTAGGA

>12236_12236_2_CABIN1-MIF_CABIN1_chr22_24530382_ENST00000263119_MIF_chr22_24236959_ENST00000215754_length(amino acids)=1663AA_BP=1584
MNMIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLIL
KYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCL
YFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFF
TWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLL
ETGAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPSRLRKLDPEEEDDSFNNYEVQSEAKLESF
PSIGPQRLSFDSATFMESEKQDVHEFLLENLTNGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHI
KDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQ
GDMEQALENYDICTEMLQSSTAIQVEAGAERRDIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCT
SGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAKEEWVATVTQLLMGIEQALSADSSGSILK
VSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEPHVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEY
LGRRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPK
TLPEFDSYKTSTVSADLANLLKRIATIVPRTERPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFY
MHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRGEL
PPELVQQMEGRRDSMLETAKHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAM
EALEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPGLTSP
PYTATPIDHDYVKCKKPHQQATPDDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEE
SLESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAGAEEQRQFLTEQCIASFRLCLSRFPQHYK
SLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQ
NRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA

--------------------------------------------------------------
>12236_12236_3_CABIN1-MIF_CABIN1_chr22_24530382_ENST00000398319_MIF_chr22_24236958_ENST00000215754_length(transcript)=5491nt_BP=5131nt
CTCAGCAGAGCCCGGGGCACAGGCCGGAGGGGCTGCAGGCGCGAGGCTGGGTTACGTGAGGAAGCTGGGGGTTTCGCGGGCAGCTTTAGA
GCCCCAGTCAGGGAAACCGAGGCCGGGCTTCCTGGCTGCCTCGCGAGCCTCTTCATGGCTCTCGCCGCCGCCCTGAGGTGCCTAGAATGG
GTTCCGGCCTCCGGGGAGGTTCCCAGTAACCGCAGGAGCCACCATTGATTTGGCGTCTGCTGGGTGCAAAGCCCAGCGCGCTAACCCTTT
ACTCGCGACCTTTCGCTTCACCTTCACAGCAGCCCTGCGAGGAGAGTTGTGGACTGGGGCAACCTTTGCCAGTGATGAGAAGTGATGCTC
GTGGCAGTGCTGAATCTCTCTGAATATGATTCGAATTGCAGCCTTAAATGCCAGCTCCACCATTGAGGATGATCATGAAGGAAGCTTTAA
AAGTCACAAAACCCAGACAAAGGAGGCTCAGGAAGCAGAGGCTTTTGCATTGTACCACAAGGCCCTTGATCTGCAGAAACATGACCGGTT
TGAGGAGTCTGCCAAAGCCTACCATGAGCTCTTGGAGGCGAGCCTGCTGCGGGAGGCAGTTTCATCCGGTGATGAGAAAGAGGGGTTGAA
ACACCCTGGGCTGATACTGAAATATTCCACTTATAAGAACTTGGCCCAGCTGGCAGCCCAGCGGGAGGATCTGGAGACAGCCATGGAGTT
CTACTTAGAGGCAGTGATGCTGGACTCCACAGATGTCAACCTCTGGTATAAGATTGGACATGTGGCCCTGAGGCTCATCCGGATCCCCCT
GGCTCGCCATGCTTTTGAGGAAGGGCTGCGGTGCAATCCTGACCACTGGCCCTGTTTGGATAACCTAATCACTGTCCTGTACACCCTCAG
TGATTACACAACATGTCTGTACTTCATCTGCAAAGCTTTGGAGAAGGATTGCCGGTACAGCAAAGGGCTGGTCCTCAAGGAGAAGATTTT
TGAGGAGCAGCCTTGTCTCCGGAAGGACTCTCTCAGAATGTTCCTCAAATGTGACATGTCGATTCACGATGTTTCGGTGAGTGCAGCTGA
GACACAGGCGATTGTAGATGAGGCCTTGGGGCTGCGAAAAAAGAGGCAAGCGCTGATTGTGCGGGAGAAGGAGCCGGACCTGAAACTTGT
GCAGCCCATTCCTTTCTTCACCTGGAAGTGCCTCGGAGAGAGCTTGCTGGCCATGTACAATCATCTCACCACCTGTGAGCCCCCACGTCC
CAGCCTTGGCAAAAGGATTGATTTGTCGGACTACCAGGACCCCAGCCAGCCTCTTGAGTCCTCCATGGTGGTGACGCCAGTTAACGTGAT
CCAGCCAAGCACTGTCAGCACCAACCCAGCTGTGGCTGTCGCCGAGCCTGTGGTCTCCTACACCTCTGTGGCTACAACCAGCTTCCCACT
GCACAGTCCTGGTCTGTTGGAGACAGGCGCTCCTGTGGGTGATATTTCTGGGGGAGATAAATCCAAGAAAGGGGTAAAACGGAAGAAGAT
TTCAGAAGAGAGTGGAGAAACAGCAAAGCGGCGGTCTGCCCGTGTCCGAAACACCAAGTGCAAAAAAGAAGAGAAAGTAGACTTCCAGGA
GCTTCTGATGAAGTTCTTGCCGTCCAGGTTAAGAAAGCTGGACCCTGAGGAGGAAGATGATTCCTTTAATAACTATGAAGTCCAGTCAGA
AGCCAAACTGGAAAGCTTCCCAAGCATTGGGCCTCAAAGGCTGTCATTTGACTCAGCCACATTCATGGAATCTGAAAAGCAGGACGTGCA
TGAGTTCCTGCTGGAGAACCTAACCAACGGGGGCATCCTGGAGCTGATGATGCGCTACCTGAAAGCCATGGGCCACAAGTTCTTGGTAAG
GTGGCCTCCAGGCTTGGCGGAGGTCGTGCTCAGCGTCTACCACAGCTGGAGGAGGCACAGCACCAGCCTGCCCAACCCGCTGCTGAGGGA
CTGCAGCAACAAGCACATCAAGGACATGATGCTGATGTCTCTCTCCTGCATGGAACTCCAGCTGGACCAGTGGCTGCTGACCAAAGGCAG
AAGCTCTGCAGTGTCTCCTCGGAACTGTCCTGCTGGTATGGTGAATGGCAGATTTGGACCTGACTTCCCAGGGACCCACTGCCTGGGTGA
CCTCCTACAGCTGTCATTTGCCTCGTCCCAGCGCGACCTGTTCGAGGATGGTTGGCTGGAGTTTGTGGTCCGTGTTTACTGGCTGAAGGC
TCGCTTCCTGGCGCTGCAGGGAGACATGGAGCAGGCCCTGGAGAACTATGACATCTGCACAGAAATGCTCCAGAGTTCCACCGCCATCCA
GGTGGAGGCAGGGGCTGAACGAAGAGACATTGTCATCCGGCTGCCCAACCTCCATAATGACTCTGTGGTTTCCCTGGAGGAGATTGATAA
GAACCTGAAGTCGCTGGAGCGGTGCCAGTCCCTGGAGGAGATTCAGCGGCTGTATGAAGCAGGCGACTACAAGGCTGTTGTGCATCTGCT
CCGCCCCACTTTGTGCACCAGTGGGTTTGACCGGGCCAAACACCTGGAGTTTATGACTTCCATTCCTGAGAGGCCAGCCCAGCTGCTTCT
TCTGCAGGACTCCTTGCTCCGGCTGAAGGACTATCGGCAGTGTTTTGAGTGTTCCGATGTGGCTCTGAACGAGGCTGTCCAGCAGATGGT
GAACTCAGGTGAGGCTGCCGCCAAGGAGGAGTGGGTGGCCACAGTGACCCAACTGCTGATGGGCATCGAGCAGGCCCTCTCTGCGGACAG
CAGTGGTAGCATCCTGAAGGTATCATCCTCCACCACTGGCCTTGTGCGGCTCACCAACAACCTCATCCAGGTCATTGACTGCAGCATGGC
TGTGCAGGAGGAGGCCAAGGAGCCCCACGTCTCTTCAGTGCTACCCTGGATCATTCTACACCGGATCATCTGGCAGGAGGAAGACACCTT
CCATTCTCTGTGCCACCAGCAGCAGCTCCAAAACCCAGCGGAGGAAGGGATGTCAGAGACGCCCATGCTCCCATCCTCCCTCATGCTGCT
GAACACAGCCCACGAGTATTTGGGCAGAAGGTCCTGGTGCTGCAATTCAGATGGGGCTCTGCTGCGATTCTATGTGCGAGTACTCCAGAA
GGAACTGGCTGCATCCACCTCTGAAGACACGCACCCTTACAAGGAGGAGCTGGAGACAGCCTTGGAGCAGTGCTTCTACTGCCTGTACAG
CTTCCCCAGCAAGAAGAGTAAGGCCAGGTACCTGGAGGAACACTCGGCCCAGCAGGTGGATCTTATATGGGAGGATGCACTGTTCATGTT
TGAGTATTTTAAGCCCAAGACCCTTCCTGAATTTGACAGCTATAAGACCAGCACCGTGTCTGCTGACTTGGCCAACCTACTGAAGAGAAT
TGCCACCATTGTGCCTCGCACAGAGAGGCCAGCCCTTAGCCTGGACAAAGTCTCTGCCTACATTGAGGGAACTTCAACTGAGGTACCCTG
CCTCCCAGAGGGGGCTGACCCCTCCCCTCCAGTGGTGAACGAGCTTTACTACCTCCTGGCTGATTATCATTTCAAAAACAAGGAGCAGTC
CAAGGCCATCAAGTTCTACATGCATGACATCTGCATCTGCCCCAATAGGTTTGATTCCTGGGCAGGCATGGCTCTGGCCCGGGCCAGCCG
CATTCAGGACAAGCTGAACTCCAATGAGCTGAAGAGTGATGGGCCCATTTGGAAGCATGCCACGCCCGTCTTGAACTGCTTCCGTCGGGC
CCTGGAGATTGACAGCTCCAACTTGTCCCTATGGATTGAGTATGGCACCATGTCCTATGCCTTGCACTCATTCGCCTCACGTCAATTGAA
GCAGTGGAGAGGCGAGCTGCCCCCTGAGCTCGTGCAGCAGATGGAGGGCCGGCGCGACAGCATGCTAGAGACAGCCAAGCACTGTTTCAC
ATCAGCAGCCCGCTGCGAGGGTGATGGTGACGAGGAGGAGTGGCTCATCCACTACATGCTGGGCAAGGTGGCTGAGAAGCAGCAGCAGCC
ACCCACCGTTTACTTGCTGCACTACAGGCAGGCTGGCCACTACCTGCACGAGGAGGCTGCCCGCTACCCCAAGAAGATCCACTACCACAA
CCCACCTGAGCTGGCCATGGAGGCCCTGGAGGTGTACTTTCGGCTCCATGCTTCCATCCTGAAGCTCCTGGGGAAGCCCGATTCTGGGGT
TGGTGCAGAGGTCCTGGTCAACTTTATGAAGGAGGCTGCAGAAGGACCCTTTGCCAGGGGCGAGGAGAAGAACACACCCAAAGCTTCAGA
AAAGGAGAAGGCCTGCCTGGTGGACGAGGACTCCCACTCTTCAGCTGGGACACTGCCGGGCCCCGGAGCCTCCCTCCCCTCCTCCTCTGG
CCCAGGTCTGACATCCCCACCTTACACAGCCACTCCGATTGACCACGATTACGTCAAATGTAAAAAACCCCACCAGCAGGCAACGCCGGA
CGACCGAAGCCAGGACAGCACAGCCGTAGCACTCTCAGACTCTAGCTCAACGCAGGACTTCTTTAATGAGCCCACCAGCTTACTGGAAGG
CTCCAGGAAATCCTACACAGAGAAGAGGCTGCCCATTCTCAGTTCCCAAGCAGGAGCGACGGGTAAAGATCTTCAGGGGGCCACAGAAGA
AAGAGGAAAAAACGAGGAGTCATTGGAGAGTACAGAAGGCTTCCGGGCTGCAGAGCAAGGTGTCCAGAAGCCTGCTGCAGAAACCCCAGC
CTCTGCTTGCATCCCTGGCAAGCCCTCAGCATCCACACCCACCCTGTGGGATGGGAAGAAGAGAGGGGACCTCCCAGGGGAGCCAGTGGC
CTTCCCCCAGGGGCTGCCGGCTGGTGCTGAGGAGCAGCGGCAGTTTCTCACAGAGCAGTGCATCGCCTCCTTCCGCCTGTGCCTGAGCCG
CTTCCCCCAGCACTATAAGAGTCTCTACCGTCTGGCCTTCCTCTACACCTACAGCAAGACCCACCGGAACCTCCAGTGGGCCCGCGACGT
GTTGCTAGGCAGCAGTATCCCGTGGCAACAACTGCAGCACATGCCGGCACAGGGGCTCTTCTGCGAGAGGAACAAGACCAATTTCTTCAA
CTACATCGCGGTGCACGTGGTCCCGGACCAGCTCATGGCCTTCGGCGGCTCCAGCGAGCCGTGCGCGCTCTGCAGCCTGCACAGCATCGG
CAAGATCGGCGGCGCGCAGAACCGCTCCTACAGCAAGCTGCTGTGCGGCCTGCTGGCCGAGCGCCTGCGCATCAGCCCGGACAGGGTCTA
CATCAACTATTACGACATGAACGCGGCCAATGTGGGCTGGAACAACTCCACCTTCGCCTAAGAGCCGCAGGGACCCACGCTGTCTGCGCT
GGCTCCACCCGGGAACCCGCCGCACGCTGTGTTCTAGGCCCGCCCACCCCAACCTTCTGGTGGGGAGAAATAAACGGTTTAGAGACTAGG
A

>12236_12236_3_CABIN1-MIF_CABIN1_chr22_24530382_ENST00000398319_MIF_chr22_24236958_ENST00000215754_length(amino acids)=1663AA_BP=1584
MNMIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLIL
KYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCL
YFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFF
TWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLL
ETGAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPSRLRKLDPEEEDDSFNNYEVQSEAKLESF
PSIGPQRLSFDSATFMESEKQDVHEFLLENLTNGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHI
KDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQ
GDMEQALENYDICTEMLQSSTAIQVEAGAERRDIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCT
SGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAKEEWVATVTQLLMGIEQALSADSSGSILK
VSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEPHVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEY
LGRRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPK
TLPEFDSYKTSTVSADLANLLKRIATIVPRTERPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFY
MHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRGEL
PPELVQQMEGRRDSMLETAKHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAM
EALEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPGLTSP
PYTATPIDHDYVKCKKPHQQATPDDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEE
SLESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAGAEEQRQFLTEQCIASFRLCLSRFPQHYK
SLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQ
NRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA

--------------------------------------------------------------
>12236_12236_4_CABIN1-MIF_CABIN1_chr22_24530382_ENST00000398319_MIF_chr22_24236959_ENST00000215754_length(transcript)=5491nt_BP=5131nt
CTCAGCAGAGCCCGGGGCACAGGCCGGAGGGGCTGCAGGCGCGAGGCTGGGTTACGTGAGGAAGCTGGGGGTTTCGCGGGCAGCTTTAGA
GCCCCAGTCAGGGAAACCGAGGCCGGGCTTCCTGGCTGCCTCGCGAGCCTCTTCATGGCTCTCGCCGCCGCCCTGAGGTGCCTAGAATGG
GTTCCGGCCTCCGGGGAGGTTCCCAGTAACCGCAGGAGCCACCATTGATTTGGCGTCTGCTGGGTGCAAAGCCCAGCGCGCTAACCCTTT
ACTCGCGACCTTTCGCTTCACCTTCACAGCAGCCCTGCGAGGAGAGTTGTGGACTGGGGCAACCTTTGCCAGTGATGAGAAGTGATGCTC
GTGGCAGTGCTGAATCTCTCTGAATATGATTCGAATTGCAGCCTTAAATGCCAGCTCCACCATTGAGGATGATCATGAAGGAAGCTTTAA
AAGTCACAAAACCCAGACAAAGGAGGCTCAGGAAGCAGAGGCTTTTGCATTGTACCACAAGGCCCTTGATCTGCAGAAACATGACCGGTT
TGAGGAGTCTGCCAAAGCCTACCATGAGCTCTTGGAGGCGAGCCTGCTGCGGGAGGCAGTTTCATCCGGTGATGAGAAAGAGGGGTTGAA
ACACCCTGGGCTGATACTGAAATATTCCACTTATAAGAACTTGGCCCAGCTGGCAGCCCAGCGGGAGGATCTGGAGACAGCCATGGAGTT
CTACTTAGAGGCAGTGATGCTGGACTCCACAGATGTCAACCTCTGGTATAAGATTGGACATGTGGCCCTGAGGCTCATCCGGATCCCCCT
GGCTCGCCATGCTTTTGAGGAAGGGCTGCGGTGCAATCCTGACCACTGGCCCTGTTTGGATAACCTAATCACTGTCCTGTACACCCTCAG
TGATTACACAACATGTCTGTACTTCATCTGCAAAGCTTTGGAGAAGGATTGCCGGTACAGCAAAGGGCTGGTCCTCAAGGAGAAGATTTT
TGAGGAGCAGCCTTGTCTCCGGAAGGACTCTCTCAGAATGTTCCTCAAATGTGACATGTCGATTCACGATGTTTCGGTGAGTGCAGCTGA
GACACAGGCGATTGTAGATGAGGCCTTGGGGCTGCGAAAAAAGAGGCAAGCGCTGATTGTGCGGGAGAAGGAGCCGGACCTGAAACTTGT
GCAGCCCATTCCTTTCTTCACCTGGAAGTGCCTCGGAGAGAGCTTGCTGGCCATGTACAATCATCTCACCACCTGTGAGCCCCCACGTCC
CAGCCTTGGCAAAAGGATTGATTTGTCGGACTACCAGGACCCCAGCCAGCCTCTTGAGTCCTCCATGGTGGTGACGCCAGTTAACGTGAT
CCAGCCAAGCACTGTCAGCACCAACCCAGCTGTGGCTGTCGCCGAGCCTGTGGTCTCCTACACCTCTGTGGCTACAACCAGCTTCCCACT
GCACAGTCCTGGTCTGTTGGAGACAGGCGCTCCTGTGGGTGATATTTCTGGGGGAGATAAATCCAAGAAAGGGGTAAAACGGAAGAAGAT
TTCAGAAGAGAGTGGAGAAACAGCAAAGCGGCGGTCTGCCCGTGTCCGAAACACCAAGTGCAAAAAAGAAGAGAAAGTAGACTTCCAGGA
GCTTCTGATGAAGTTCTTGCCGTCCAGGTTAAGAAAGCTGGACCCTGAGGAGGAAGATGATTCCTTTAATAACTATGAAGTCCAGTCAGA
AGCCAAACTGGAAAGCTTCCCAAGCATTGGGCCTCAAAGGCTGTCATTTGACTCAGCCACATTCATGGAATCTGAAAAGCAGGACGTGCA
TGAGTTCCTGCTGGAGAACCTAACCAACGGGGGCATCCTGGAGCTGATGATGCGCTACCTGAAAGCCATGGGCCACAAGTTCTTGGTAAG
GTGGCCTCCAGGCTTGGCGGAGGTCGTGCTCAGCGTCTACCACAGCTGGAGGAGGCACAGCACCAGCCTGCCCAACCCGCTGCTGAGGGA
CTGCAGCAACAAGCACATCAAGGACATGATGCTGATGTCTCTCTCCTGCATGGAACTCCAGCTGGACCAGTGGCTGCTGACCAAAGGCAG
AAGCTCTGCAGTGTCTCCTCGGAACTGTCCTGCTGGTATGGTGAATGGCAGATTTGGACCTGACTTCCCAGGGACCCACTGCCTGGGTGA
CCTCCTACAGCTGTCATTTGCCTCGTCCCAGCGCGACCTGTTCGAGGATGGTTGGCTGGAGTTTGTGGTCCGTGTTTACTGGCTGAAGGC
TCGCTTCCTGGCGCTGCAGGGAGACATGGAGCAGGCCCTGGAGAACTATGACATCTGCACAGAAATGCTCCAGAGTTCCACCGCCATCCA
GGTGGAGGCAGGGGCTGAACGAAGAGACATTGTCATCCGGCTGCCCAACCTCCATAATGACTCTGTGGTTTCCCTGGAGGAGATTGATAA
GAACCTGAAGTCGCTGGAGCGGTGCCAGTCCCTGGAGGAGATTCAGCGGCTGTATGAAGCAGGCGACTACAAGGCTGTTGTGCATCTGCT
CCGCCCCACTTTGTGCACCAGTGGGTTTGACCGGGCCAAACACCTGGAGTTTATGACTTCCATTCCTGAGAGGCCAGCCCAGCTGCTTCT
TCTGCAGGACTCCTTGCTCCGGCTGAAGGACTATCGGCAGTGTTTTGAGTGTTCCGATGTGGCTCTGAACGAGGCTGTCCAGCAGATGGT
GAACTCAGGTGAGGCTGCCGCCAAGGAGGAGTGGGTGGCCACAGTGACCCAACTGCTGATGGGCATCGAGCAGGCCCTCTCTGCGGACAG
CAGTGGTAGCATCCTGAAGGTATCATCCTCCACCACTGGCCTTGTGCGGCTCACCAACAACCTCATCCAGGTCATTGACTGCAGCATGGC
TGTGCAGGAGGAGGCCAAGGAGCCCCACGTCTCTTCAGTGCTACCCTGGATCATTCTACACCGGATCATCTGGCAGGAGGAAGACACCTT
CCATTCTCTGTGCCACCAGCAGCAGCTCCAAAACCCAGCGGAGGAAGGGATGTCAGAGACGCCCATGCTCCCATCCTCCCTCATGCTGCT
GAACACAGCCCACGAGTATTTGGGCAGAAGGTCCTGGTGCTGCAATTCAGATGGGGCTCTGCTGCGATTCTATGTGCGAGTACTCCAGAA
GGAACTGGCTGCATCCACCTCTGAAGACACGCACCCTTACAAGGAGGAGCTGGAGACAGCCTTGGAGCAGTGCTTCTACTGCCTGTACAG
CTTCCCCAGCAAGAAGAGTAAGGCCAGGTACCTGGAGGAACACTCGGCCCAGCAGGTGGATCTTATATGGGAGGATGCACTGTTCATGTT
TGAGTATTTTAAGCCCAAGACCCTTCCTGAATTTGACAGCTATAAGACCAGCACCGTGTCTGCTGACTTGGCCAACCTACTGAAGAGAAT
TGCCACCATTGTGCCTCGCACAGAGAGGCCAGCCCTTAGCCTGGACAAAGTCTCTGCCTACATTGAGGGAACTTCAACTGAGGTACCCTG
CCTCCCAGAGGGGGCTGACCCCTCCCCTCCAGTGGTGAACGAGCTTTACTACCTCCTGGCTGATTATCATTTCAAAAACAAGGAGCAGTC
CAAGGCCATCAAGTTCTACATGCATGACATCTGCATCTGCCCCAATAGGTTTGATTCCTGGGCAGGCATGGCTCTGGCCCGGGCCAGCCG
CATTCAGGACAAGCTGAACTCCAATGAGCTGAAGAGTGATGGGCCCATTTGGAAGCATGCCACGCCCGTCTTGAACTGCTTCCGTCGGGC
CCTGGAGATTGACAGCTCCAACTTGTCCCTATGGATTGAGTATGGCACCATGTCCTATGCCTTGCACTCATTCGCCTCACGTCAATTGAA
GCAGTGGAGAGGCGAGCTGCCCCCTGAGCTCGTGCAGCAGATGGAGGGCCGGCGCGACAGCATGCTAGAGACAGCCAAGCACTGTTTCAC
ATCAGCAGCCCGCTGCGAGGGTGATGGTGACGAGGAGGAGTGGCTCATCCACTACATGCTGGGCAAGGTGGCTGAGAAGCAGCAGCAGCC
ACCCACCGTTTACTTGCTGCACTACAGGCAGGCTGGCCACTACCTGCACGAGGAGGCTGCCCGCTACCCCAAGAAGATCCACTACCACAA
CCCACCTGAGCTGGCCATGGAGGCCCTGGAGGTGTACTTTCGGCTCCATGCTTCCATCCTGAAGCTCCTGGGGAAGCCCGATTCTGGGGT
TGGTGCAGAGGTCCTGGTCAACTTTATGAAGGAGGCTGCAGAAGGACCCTTTGCCAGGGGCGAGGAGAAGAACACACCCAAAGCTTCAGA
AAAGGAGAAGGCCTGCCTGGTGGACGAGGACTCCCACTCTTCAGCTGGGACACTGCCGGGCCCCGGAGCCTCCCTCCCCTCCTCCTCTGG
CCCAGGTCTGACATCCCCACCTTACACAGCCACTCCGATTGACCACGATTACGTCAAATGTAAAAAACCCCACCAGCAGGCAACGCCGGA
CGACCGAAGCCAGGACAGCACAGCCGTAGCACTCTCAGACTCTAGCTCAACGCAGGACTTCTTTAATGAGCCCACCAGCTTACTGGAAGG
CTCCAGGAAATCCTACACAGAGAAGAGGCTGCCCATTCTCAGTTCCCAAGCAGGAGCGACGGGTAAAGATCTTCAGGGGGCCACAGAAGA
AAGAGGAAAAAACGAGGAGTCATTGGAGAGTACAGAAGGCTTCCGGGCTGCAGAGCAAGGTGTCCAGAAGCCTGCTGCAGAAACCCCAGC
CTCTGCTTGCATCCCTGGCAAGCCCTCAGCATCCACACCCACCCTGTGGGATGGGAAGAAGAGAGGGGACCTCCCAGGGGAGCCAGTGGC
CTTCCCCCAGGGGCTGCCGGCTGGTGCTGAGGAGCAGCGGCAGTTTCTCACAGAGCAGTGCATCGCCTCCTTCCGCCTGTGCCTGAGCCG
CTTCCCCCAGCACTATAAGAGTCTCTACCGTCTGGCCTTCCTCTACACCTACAGCAAGACCCACCGGAACCTCCAGTGGGCCCGCGACGT
GTTGCTAGGCAGCAGTATCCCGTGGCAACAACTGCAGCACATGCCGGCACAGGGGCTCTTCTGCGAGAGGAACAAGACCAATTTCTTCAA
CTACATCGCGGTGCACGTGGTCCCGGACCAGCTCATGGCCTTCGGCGGCTCCAGCGAGCCGTGCGCGCTCTGCAGCCTGCACAGCATCGG
CAAGATCGGCGGCGCGCAGAACCGCTCCTACAGCAAGCTGCTGTGCGGCCTGCTGGCCGAGCGCCTGCGCATCAGCCCGGACAGGGTCTA
CATCAACTATTACGACATGAACGCGGCCAATGTGGGCTGGAACAACTCCACCTTCGCCTAAGAGCCGCAGGGACCCACGCTGTCTGCGCT
GGCTCCACCCGGGAACCCGCCGCACGCTGTGTTCTAGGCCCGCCCACCCCAACCTTCTGGTGGGGAGAAATAAACGGTTTAGAGACTAGG
A

>12236_12236_4_CABIN1-MIF_CABIN1_chr22_24530382_ENST00000398319_MIF_chr22_24236959_ENST00000215754_length(amino acids)=1663AA_BP=1584
MNMIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLIL
KYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCL
YFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFF
TWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLL
ETGAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPSRLRKLDPEEEDDSFNNYEVQSEAKLESF
PSIGPQRLSFDSATFMESEKQDVHEFLLENLTNGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHI
KDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQ
GDMEQALENYDICTEMLQSSTAIQVEAGAERRDIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCT
SGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAKEEWVATVTQLLMGIEQALSADSSGSILK
VSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEPHVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEY
LGRRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPK
TLPEFDSYKTSTVSADLANLLKRIATIVPRTERPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFY
MHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRGEL
PPELVQQMEGRRDSMLETAKHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAM
EALEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPGLTSP
PYTATPIDHDYVKCKKPHQQATPDDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEE
SLESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAGAEEQRQFLTEQCIASFRLCLSRFPQHYK
SLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQ
NRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA

--------------------------------------------------------------
>12236_12236_5_CABIN1-MIF_CABIN1_chr22_24530382_ENST00000405822_MIF_chr22_24236958_ENST00000215754_length(transcript)=4963nt_BP=4603nt
CGTTGCTGTGGAGACGCCTGGAGAGTTGTGGACTGGGGCAACCTTTGCCAGTGATGAGAAGTGATGCTCGTGGCAGTGCTGAATCTCTCT
GAATATGATTCGAATTGCAGCCTTAAATGCCAGCTCCACCATTGAGGATGATCATGAAGGAAGCTTTAAAAGTCACAAAACCCAGACAAA
GGAGGCTCAGGAAGCAGAGGCTTTTGCATTGTACCACAAGGCCCTTGATCTGCAGAAACATGACCGGTTTGAGGAGTCTGCCAAAGCCTA
CCATGAGCTCTTGGAGGCGAGCCTGCTGCGGGAGGCAGTTTCATCCGGTGATGAGAAAGAGGGGTTGAAACACCCTGGGCTGATACTGAA
ATATTCCACTTATAAGAACTTGGCCCAGCTGGCAGCCCAGCGGGAGGATCTGGAGACAGCCATGGAGTTCTACTTAGAGGCAGTGATGCT
GGACTCCACAGATGTCAACCTCTGGTATAAGATTGGACATGTGGCCCTGAGGCTCATCCGGATCCCCCTGGCTCGCCATGCTTTTGAGGA
AGGGCTGCGGTGCAATCCTGACCACTGGCCCTGTTTGGATAACCTAATCACTGTCCTGTACACCCTCAGTGATTACACAACATGTCTGTA
CTTCATCTGCAAAGCTTTGGAGAAGGATTGCCGGTACAGCAAAGGGCTGGTCCTCAAGGAGAAGATTTTTGAGGAGCAGCCTTGTCTCCG
GAAGGACTCTCTCAGAATGTTCCTCAAATGCTGGAAGTGCCTCGGAGAGAGCTTGCTGGCCATGTACAATCATCTCACCACCTGTGAGCC
CCCACGTCCCAGCCTTGGCAAAAGGATTGATTTGTCGGACTACCAGGACCCCAGCCAGCCTCTTGAGTCCTCCATGGTGGTGACGCCAGT
TAACGTGATCCAGCCAAGCACTGTCAGCACCAACCCAGCTGTGGCTGTCGCCGAGCCTGTGGTCTCCTACACCTCTGTGGCTACAACCAG
CTTCCCACTGCACAGTCCTGGTCTGTTGGAGACAGGCGCTCCTGTGGGTGATATTTCTGGGGGAGATAAATCCAAGAAAGGGGTAAAACG
GAAGAAGATTTCAGAAGAGAGTGGAGAAACAGCAAAGCGGCGGTCTGCCCGTGTCCGAAACACCAAGTGCAAAAAAGAAGAGAAAGTAGA
CTTCCAGGAGCTTCTGATGAAGTTCTTGCCGTCCAGGTTAAGAAAGCTGGACCCTGAGGAGGAAGATGATTCCTTTAATAACTATGAAGT
CCAGTCAGAAGCCAAACTGGAAAGCTTCCCAAGCATTGGGCCTCAAAGGCTGTCATTTGACTCAGCCACATTCATGGAATCTGAAAAGCA
GGACGTGCATGAGTTCCTGCTGGAGAACCTAACCAACGGGGGCATCCTGGAGCTGATGATGCGCTACCTGAAAGCCATGGGCCACAAGTT
CTTGGTAAGGTGGCCTCCAGGCTTGGCGGAGGTCGTGCTCAGCGTCTACCACAGCTGGAGGAGGCACAGCACCAGCCTGCCCAACCCGCT
GCTGAGGGACTGCAGCAACAAGCACATCAAGGACATGATGCTGATGTCTCTCTCCTGCATGGAACTCCAGCTGGACCAGTGGCTGCTGAC
CAAAGGCAGAAGCTCTGCAGTGTCTCCTCGGAACTGTCCTGCTGGTATGGTGAATGGCAGATTTGGACCTGACTTCCCAGGGACCCACTG
CCTGGGTGACCTCCTACAGCTGTCATTTGCCTCGTCCCAGCGCGACCTGTTCGAGGATGGTTGGCTGGAGTTTGTGGTCCGTGTTTACTG
GCTGAAGGCTCGCTTCCTGGCGCTGCAGGGAGACATGGAGCAGGCCCTGGAGAACTATGACATCTGCACAGAAATGCTCCAGAGTTCCAC
CGCCATCCAGGTGGAGGCAGGGGCTGAACGAAGAGACATTGTCATCCGGCTGCCCAACCTCCATAATGACTCTGTGGTTTCCCTGGAGGA
GATTGATAAGAACCTGAAGTCGCTGGAGCGGTGCCAGTCCCTGGAGGAGATTCAGCGGCTGTATGAAGCAGGCGACTACAAGGCTGTTGT
GCATCTGCTCCGCCCCACTTTGTGCACCAGTGGGTTTGACCGGGCCAAACACCTGGAGTTTATGACTTCCATTCCTGAGAGGCCAGCCCA
GCTGCTTCTTCTGCAGGACTCCTTGCTCCGGCTGAAGGACTATCGGCAGTGTTTTGAGTGTTCCGATGTGGCTCTGAACGAGGCTGTCCA
GCAGATGGTGAACTCAGGTGAGGCTGCCGCCAAGGAGGAGTGGGTGGCCACAGTGACCCAACTGCTGATGGGCATCGAGCAGGCCCTCTC
TGCGGACAGCAGTGGTAGCATCCTGAAGGTATCATCCTCCACCACTGGCCTTGTGCGGCTCACCAACAACCTCATCCAGGTCATTGACTG
CAGCATGGCTGTGCAGGAGGAGGCCAAGGAGCCCCACGTCTCTTCAGTGCTACCCTGGATCATTCTACACCGGATCATCTGGCAGGAGGA
AGACACCTTCCATTCTCTGTGCCACCAGCAGCAGCTCCAAAACCCAGCGGAGGAAGGGATGTCAGAGACGCCCATGCTCCCATCCTCCCT
CATGCTGCTGAACACAGCCCACGAGTATTTGGGCAGAAGGTCCTGGTGCTGCAATTCAGATGGGGCTCTGCTGCGATTCTATGTGCGAGT
ACTCCAGAAGGAACTGGCTGCATCCACCTCTGAAGACACGCACCCTTACAAGGAGGAGCTGGAGACAGCCTTGGAGCAGTGCTTCTACTG
CCTGTACAGCTTCCCCAGCAAGAAGAGTAAGGCCAGGTACCTGGAGGAACACTCGGCCCAGCAGGTGGATCTTATATGGGAGGATGCACT
GTTCATGTTTGAGTATTTTAAGCCCAAGACCCTTCCTGAATTTGACAGCTATAAGACCAGCACCGTGTCTGCTGACTTGGCCAACCTACT
GAAGAGAATTGCCACCATTGTGCCTCGCACAGAGAGGCCAGCCCTTAGCCTGGACAAAGTCTCTGCCTACATTGAGGGAACTTCAACTGA
GGTACCCTGCCTCCCAGAGGGGGCTGACCCCTCCCCTCCAGTGGTGAACGAGCTTTACTACCTCCTGGCTGATTATCATTTCAAAAACAA
GGAGCAGTCCAAGGCCATCAAGTTCTACATGCATGACATCTGCATCTGCCCCAATAGGTTTGATTCCTGGGCAGGCATGGCTCTGGCCCG
GGCCAGCCGCATTCAGGACAAGCTGAACTCCAATGAGCTGAAGAGTGATGGGCCCATTTGGAAGCATGCCACGCCCGTCTTGAACTGCTT
CCGTCGGGCCCTGGAGATTGACAGCTCCAACTTGTCCCTATGGATTGAGTATGGCACCATGTCCTATGCCTTGCACTCATTCGCCTCACG
TCAATTGAAGCAGTGGAGAGGCGAGCTGCCCCCTGAGCTCGTGCAGCAGATGGAGGGCCGGCGCGACAGCATGCTAGAGACAGCCAAGCA
CTGTTTCACATCAGCAGCCCGCTGCGAGGGTGATGGTGACGAGGAGGAGTGGCTCATCCACTACATGCTGGGCAAGGTGGCTGAGAAGCA
GCAGCAGCCACCCACCGTTTACTTGCTGCACTACAGGCAGGCTGGCCACTACCTGCACGAGGAGGCTGCCCGCTACCCCAAGAAGATCCA
CTACCACAACCCACCTGAGCTGGCCATGGAGGCCCTGGAGGTGTACTTTCGGCTCCATGCTTCCATCCTGAAGCTCCTGGGGAAGCCCGA
TTCTGGGGTTGGTGCAGAGGTCCTGGTCAACTTTATGAAGGAGGCTGCAGAAGGACCCTTTGCCAGGGGCGAGGAGAAGAACACACCCAA
AGCTTCAGAAAAGGAGAAGGCCTGCCTGGTGGACGAGGACTCCCACTCTTCAGCTGGGACACTGCCGGGCCCCGGAGCCTCCCTCCCCTC
CTCCTCTGGCCCAGACCGAAGCCAGGACAGCACAGCCGTAGCACTCTCAGACTCTAGCTCAACGCAGGACTTCTTTAATGAGCCCACCAG
CTTACTGGAAGGCTCCAGGAAATCCTACACAGAGAAGAGGCTGCCCATTCTCAGTTCCCAAGCAGGAGCGACGGGTAAAGATCTTCAGGG
GGCCACAGAAGAAAGAGGAAAAAACGAGGAGTCATTGGAGAGTACAGAAGGCTTCCGGGCTGCAGAGCAAGGTGTCCAGAAGCCTGCTGC
AGAAACCCCAGCCTCTGCTTGCATCCCTGGCAAGCCCTCAGCATCCACACCCACCCTGTGGGATGGGAAGAAGAGAGGGGACCTCCCAGG
GGAGCCAGTGGCCTTCCCCCAGGGGCTGCCGGCTGGTGCTGAGGAGCAGCGGCAGTTTCTCACAGAGCAGTGCATCGCCTCCTTCCGCCT
GTGCCTGAGCCGCTTCCCCCAGCACTATAAGAGTCTCTACCGTCTGGCCTTCCTCTACACCTACAGCAAGACCCACCGGAACCTCCAGTG
GGCCCGCGACGTGTTGCTAGGCAGCAGTATCCCGTGGCAACAACTGCAGCACATGCCGGCACAGGGGCTCTTCTGCGAGAGGAACAAGAC
CAATTTCTTCAACTACATCGCGGTGCACGTGGTCCCGGACCAGCTCATGGCCTTCGGCGGCTCCAGCGAGCCGTGCGCGCTCTGCAGCCT
GCACAGCATCGGCAAGATCGGCGGCGCGCAGAACCGCTCCTACAGCAAGCTGCTGTGCGGCCTGCTGGCCGAGCGCCTGCGCATCAGCCC
GGACAGGGTCTACATCAACTATTACGACATGAACGCGGCCAATGTGGGCTGGAACAACTCCACCTTCGCCTAAGAGCCGCAGGGACCCAC
GCTGTCTGCGCTGGCTCCACCCGGGAACCCGCCGCACGCTGTGTTCTAGGCCCGCCCACCCCAACCTTCTGGTGGGGAGAAATAAACGGT
TTAGAGACTAGGA

>12236_12236_5_CABIN1-MIF_CABIN1_chr22_24530382_ENST00000405822_MIF_chr22_24236958_ENST00000215754_length(amino acids)=1584AA_BP=1505
MNMIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLIL
KYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCL
YFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQPLESSMVVTP
VNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLETGAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKV
DFQELLMKFLPSRLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLTNGGILELMMRYLKAMGHK
FLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTH
CLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERRDIVIRLPNLHNDSVVSLE
EIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAV
QQMVNSGEAAAKEEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEPHVSSVLPWIILHRIIWQE
EDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFY
CLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTERPALSLDKVSAYIEGTST
EVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNC
FRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGDGDEEEWLIHYMLGKVAEK
QQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTP
KASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQ
GATEERGKNEESLESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAGAEEQRQFLTEQCIASFR
LCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNYIAVHVVPDQLMAFGGSSEPCALCS
LHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA

--------------------------------------------------------------
>12236_12236_6_CABIN1-MIF_CABIN1_chr22_24530382_ENST00000405822_MIF_chr22_24236959_ENST00000215754_length(transcript)=4963nt_BP=4603nt
CGTTGCTGTGGAGACGCCTGGAGAGTTGTGGACTGGGGCAACCTTTGCCAGTGATGAGAAGTGATGCTCGTGGCAGTGCTGAATCTCTCT
GAATATGATTCGAATTGCAGCCTTAAATGCCAGCTCCACCATTGAGGATGATCATGAAGGAAGCTTTAAAAGTCACAAAACCCAGACAAA
GGAGGCTCAGGAAGCAGAGGCTTTTGCATTGTACCACAAGGCCCTTGATCTGCAGAAACATGACCGGTTTGAGGAGTCTGCCAAAGCCTA
CCATGAGCTCTTGGAGGCGAGCCTGCTGCGGGAGGCAGTTTCATCCGGTGATGAGAAAGAGGGGTTGAAACACCCTGGGCTGATACTGAA
ATATTCCACTTATAAGAACTTGGCCCAGCTGGCAGCCCAGCGGGAGGATCTGGAGACAGCCATGGAGTTCTACTTAGAGGCAGTGATGCT
GGACTCCACAGATGTCAACCTCTGGTATAAGATTGGACATGTGGCCCTGAGGCTCATCCGGATCCCCCTGGCTCGCCATGCTTTTGAGGA
AGGGCTGCGGTGCAATCCTGACCACTGGCCCTGTTTGGATAACCTAATCACTGTCCTGTACACCCTCAGTGATTACACAACATGTCTGTA
CTTCATCTGCAAAGCTTTGGAGAAGGATTGCCGGTACAGCAAAGGGCTGGTCCTCAAGGAGAAGATTTTTGAGGAGCAGCCTTGTCTCCG
GAAGGACTCTCTCAGAATGTTCCTCAAATGCTGGAAGTGCCTCGGAGAGAGCTTGCTGGCCATGTACAATCATCTCACCACCTGTGAGCC
CCCACGTCCCAGCCTTGGCAAAAGGATTGATTTGTCGGACTACCAGGACCCCAGCCAGCCTCTTGAGTCCTCCATGGTGGTGACGCCAGT
TAACGTGATCCAGCCAAGCACTGTCAGCACCAACCCAGCTGTGGCTGTCGCCGAGCCTGTGGTCTCCTACACCTCTGTGGCTACAACCAG
CTTCCCACTGCACAGTCCTGGTCTGTTGGAGACAGGCGCTCCTGTGGGTGATATTTCTGGGGGAGATAAATCCAAGAAAGGGGTAAAACG
GAAGAAGATTTCAGAAGAGAGTGGAGAAACAGCAAAGCGGCGGTCTGCCCGTGTCCGAAACACCAAGTGCAAAAAAGAAGAGAAAGTAGA
CTTCCAGGAGCTTCTGATGAAGTTCTTGCCGTCCAGGTTAAGAAAGCTGGACCCTGAGGAGGAAGATGATTCCTTTAATAACTATGAAGT
CCAGTCAGAAGCCAAACTGGAAAGCTTCCCAAGCATTGGGCCTCAAAGGCTGTCATTTGACTCAGCCACATTCATGGAATCTGAAAAGCA
GGACGTGCATGAGTTCCTGCTGGAGAACCTAACCAACGGGGGCATCCTGGAGCTGATGATGCGCTACCTGAAAGCCATGGGCCACAAGTT
CTTGGTAAGGTGGCCTCCAGGCTTGGCGGAGGTCGTGCTCAGCGTCTACCACAGCTGGAGGAGGCACAGCACCAGCCTGCCCAACCCGCT
GCTGAGGGACTGCAGCAACAAGCACATCAAGGACATGATGCTGATGTCTCTCTCCTGCATGGAACTCCAGCTGGACCAGTGGCTGCTGAC
CAAAGGCAGAAGCTCTGCAGTGTCTCCTCGGAACTGTCCTGCTGGTATGGTGAATGGCAGATTTGGACCTGACTTCCCAGGGACCCACTG
CCTGGGTGACCTCCTACAGCTGTCATTTGCCTCGTCCCAGCGCGACCTGTTCGAGGATGGTTGGCTGGAGTTTGTGGTCCGTGTTTACTG
GCTGAAGGCTCGCTTCCTGGCGCTGCAGGGAGACATGGAGCAGGCCCTGGAGAACTATGACATCTGCACAGAAATGCTCCAGAGTTCCAC
CGCCATCCAGGTGGAGGCAGGGGCTGAACGAAGAGACATTGTCATCCGGCTGCCCAACCTCCATAATGACTCTGTGGTTTCCCTGGAGGA
GATTGATAAGAACCTGAAGTCGCTGGAGCGGTGCCAGTCCCTGGAGGAGATTCAGCGGCTGTATGAAGCAGGCGACTACAAGGCTGTTGT
GCATCTGCTCCGCCCCACTTTGTGCACCAGTGGGTTTGACCGGGCCAAACACCTGGAGTTTATGACTTCCATTCCTGAGAGGCCAGCCCA
GCTGCTTCTTCTGCAGGACTCCTTGCTCCGGCTGAAGGACTATCGGCAGTGTTTTGAGTGTTCCGATGTGGCTCTGAACGAGGCTGTCCA
GCAGATGGTGAACTCAGGTGAGGCTGCCGCCAAGGAGGAGTGGGTGGCCACAGTGACCCAACTGCTGATGGGCATCGAGCAGGCCCTCTC
TGCGGACAGCAGTGGTAGCATCCTGAAGGTATCATCCTCCACCACTGGCCTTGTGCGGCTCACCAACAACCTCATCCAGGTCATTGACTG
CAGCATGGCTGTGCAGGAGGAGGCCAAGGAGCCCCACGTCTCTTCAGTGCTACCCTGGATCATTCTACACCGGATCATCTGGCAGGAGGA
AGACACCTTCCATTCTCTGTGCCACCAGCAGCAGCTCCAAAACCCAGCGGAGGAAGGGATGTCAGAGACGCCCATGCTCCCATCCTCCCT
CATGCTGCTGAACACAGCCCACGAGTATTTGGGCAGAAGGTCCTGGTGCTGCAATTCAGATGGGGCTCTGCTGCGATTCTATGTGCGAGT
ACTCCAGAAGGAACTGGCTGCATCCACCTCTGAAGACACGCACCCTTACAAGGAGGAGCTGGAGACAGCCTTGGAGCAGTGCTTCTACTG
CCTGTACAGCTTCCCCAGCAAGAAGAGTAAGGCCAGGTACCTGGAGGAACACTCGGCCCAGCAGGTGGATCTTATATGGGAGGATGCACT
GTTCATGTTTGAGTATTTTAAGCCCAAGACCCTTCCTGAATTTGACAGCTATAAGACCAGCACCGTGTCTGCTGACTTGGCCAACCTACT
GAAGAGAATTGCCACCATTGTGCCTCGCACAGAGAGGCCAGCCCTTAGCCTGGACAAAGTCTCTGCCTACATTGAGGGAACTTCAACTGA
GGTACCCTGCCTCCCAGAGGGGGCTGACCCCTCCCCTCCAGTGGTGAACGAGCTTTACTACCTCCTGGCTGATTATCATTTCAAAAACAA
GGAGCAGTCCAAGGCCATCAAGTTCTACATGCATGACATCTGCATCTGCCCCAATAGGTTTGATTCCTGGGCAGGCATGGCTCTGGCCCG
GGCCAGCCGCATTCAGGACAAGCTGAACTCCAATGAGCTGAAGAGTGATGGGCCCATTTGGAAGCATGCCACGCCCGTCTTGAACTGCTT
CCGTCGGGCCCTGGAGATTGACAGCTCCAACTTGTCCCTATGGATTGAGTATGGCACCATGTCCTATGCCTTGCACTCATTCGCCTCACG
TCAATTGAAGCAGTGGAGAGGCGAGCTGCCCCCTGAGCTCGTGCAGCAGATGGAGGGCCGGCGCGACAGCATGCTAGAGACAGCCAAGCA
CTGTTTCACATCAGCAGCCCGCTGCGAGGGTGATGGTGACGAGGAGGAGTGGCTCATCCACTACATGCTGGGCAAGGTGGCTGAGAAGCA
GCAGCAGCCACCCACCGTTTACTTGCTGCACTACAGGCAGGCTGGCCACTACCTGCACGAGGAGGCTGCCCGCTACCCCAAGAAGATCCA
CTACCACAACCCACCTGAGCTGGCCATGGAGGCCCTGGAGGTGTACTTTCGGCTCCATGCTTCCATCCTGAAGCTCCTGGGGAAGCCCGA
TTCTGGGGTTGGTGCAGAGGTCCTGGTCAACTTTATGAAGGAGGCTGCAGAAGGACCCTTTGCCAGGGGCGAGGAGAAGAACACACCCAA
AGCTTCAGAAAAGGAGAAGGCCTGCCTGGTGGACGAGGACTCCCACTCTTCAGCTGGGACACTGCCGGGCCCCGGAGCCTCCCTCCCCTC
CTCCTCTGGCCCAGACCGAAGCCAGGACAGCACAGCCGTAGCACTCTCAGACTCTAGCTCAACGCAGGACTTCTTTAATGAGCCCACCAG
CTTACTGGAAGGCTCCAGGAAATCCTACACAGAGAAGAGGCTGCCCATTCTCAGTTCCCAAGCAGGAGCGACGGGTAAAGATCTTCAGGG
GGCCACAGAAGAAAGAGGAAAAAACGAGGAGTCATTGGAGAGTACAGAAGGCTTCCGGGCTGCAGAGCAAGGTGTCCAGAAGCCTGCTGC
AGAAACCCCAGCCTCTGCTTGCATCCCTGGCAAGCCCTCAGCATCCACACCCACCCTGTGGGATGGGAAGAAGAGAGGGGACCTCCCAGG
GGAGCCAGTGGCCTTCCCCCAGGGGCTGCCGGCTGGTGCTGAGGAGCAGCGGCAGTTTCTCACAGAGCAGTGCATCGCCTCCTTCCGCCT
GTGCCTGAGCCGCTTCCCCCAGCACTATAAGAGTCTCTACCGTCTGGCCTTCCTCTACACCTACAGCAAGACCCACCGGAACCTCCAGTG
GGCCCGCGACGTGTTGCTAGGCAGCAGTATCCCGTGGCAACAACTGCAGCACATGCCGGCACAGGGGCTCTTCTGCGAGAGGAACAAGAC
CAATTTCTTCAACTACATCGCGGTGCACGTGGTCCCGGACCAGCTCATGGCCTTCGGCGGCTCCAGCGAGCCGTGCGCGCTCTGCAGCCT
GCACAGCATCGGCAAGATCGGCGGCGCGCAGAACCGCTCCTACAGCAAGCTGCTGTGCGGCCTGCTGGCCGAGCGCCTGCGCATCAGCCC
GGACAGGGTCTACATCAACTATTACGACATGAACGCGGCCAATGTGGGCTGGAACAACTCCACCTTCGCCTAAGAGCCGCAGGGACCCAC
GCTGTCTGCGCTGGCTCCACCCGGGAACCCGCCGCACGCTGTGTTCTAGGCCCGCCCACCCCAACCTTCTGGTGGGGAGAAATAAACGGT
TTAGAGACTAGGA

>12236_12236_6_CABIN1-MIF_CABIN1_chr22_24530382_ENST00000405822_MIF_chr22_24236959_ENST00000215754_length(amino acids)=1584AA_BP=1505
MNMIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLIL
KYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCL
YFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQPLESSMVVTP
VNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLETGAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKV
DFQELLMKFLPSRLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLTNGGILELMMRYLKAMGHK
FLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTH
CLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERRDIVIRLPNLHNDSVVSLE
EIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAV
QQMVNSGEAAAKEEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEPHVSSVLPWIILHRIIWQE
EDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFY
CLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTERPALSLDKVSAYIEGTST
EVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNC
FRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGDGDEEEWLIHYMLGKVAEK
QQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTP
KASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQ
GATEERGKNEESLESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAGAEEQRQFLTEQCIASFR
LCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNYIAVHVVPDQLMAFGGSSEPCALCS
LHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CABIN1-MIF


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CABIN1-MIF


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CABIN1-MIF


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCABIN1C0018800Cardiomegaly1CTD_human
HgeneCABIN1C1383860Cardiac Hypertrophy1CTD_human
TgeneC0003469Anxiety Disorders1CTD_human
TgeneC0003873Rheumatoid Arthritis1CTD_human
TgeneC0004352Autistic Disorder1CTD_human
TgeneC0006142Malignant neoplasm of breast1CTD_human
TgeneC0007097Carcinoma1CTD_human
TgeneC0009319Colitis1CTD_human
TgeneC0011573Endogenous depression1CTD_human
TgeneC0011581Depressive disorder1CTD_human
TgeneC0014518Toxic Epidermal Necrolysis1CTD_human
TgeneC0021368Inflammation1CTD_human
TgeneC0022548Keloid1CTD_human
TgeneC0024667Animal Mammary Neoplasms1CTD_human
TgeneC0024668Mammary Neoplasms, Experimental1CTD_human
TgeneC0025193Melancholia1CTD_human
TgeneC0025261Memory Disorders1CTD_human
TgeneC0033578Prostatic Neoplasms1CTD_human
TgeneC0034189Pyemia1CTD_human
TgeneC0036690Septicemia1CTD_human
TgeneC0038325Stevens-Johnson Syndrome1CTD_human
TgeneC0041696Unipolar Depression1CTD_human
TgeneC0086133Depressive Syndrome1CTD_human
TgeneC0205696Anaplastic carcinoma1CTD_human
TgeneC0205697Carcinoma, Spindle-Cell1CTD_human
TgeneC0205698Undifferentiated carcinoma1CTD_human
TgeneC0205699Carcinomatosis1CTD_human
TgeneC0233794Memory impairment1CTD_human
TgeneC0243026Sepsis1CTD_human
TgeneC0282126Depression, Neurotic1CTD_human
TgeneC0345967Malignant mesothelioma1CTD_human
TgeneC0376280Anxiety States, Neurotic1CTD_human
TgeneC0376358Malignant neoplasm of prostate1CTD_human
TgeneC0678222Breast Carcinoma1CTD_human
TgeneC0751292Age-Related Memory Disorders1CTD_human
TgeneC0751293Memory Disorder, Semantic1CTD_human
TgeneC0751294Memory Disorder, Spatial1CTD_human
TgeneC0751295Memory Loss1CTD_human
TgeneC1257925Mammary Carcinoma, Animal1CTD_human
TgeneC1257931Mammary Neoplasms, Human1CTD_human
TgeneC1274933Drug-Induced Stevens Johnson Syndrome1CTD_human
TgeneC1279420Anxiety neurosis (finding)1CTD_human
TgeneC1458155Mammary Neoplasms1CTD_human
TgeneC1719672Severe Sepsis1CTD_human
TgeneC3658301Mycoplasma-Induced Stevens-Johnson Syndrome1CTD_human
TgeneC3658302Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum1CTD_human
TgeneC4704874Mammary Carcinoma, Human1CTD_human