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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BCL2L13-GAB4 (FusionGDB2 ID:HG23786TG128954)

Fusion Gene Summary for BCL2L13-GAB4

check button Fusion gene summary
Fusion gene informationFusion gene name: BCL2L13-GAB4
Fusion gene ID: hg23786tg128954
HgeneTgene
Gene symbol

BCL2L13

GAB4

Gene ID

23786

128954

Gene nameBCL2 like 13GRB2 associated binding protein family member 4
SynonymsBCL-RAMBO|Bcl2-L-13|MIL1-
Cytomap('BCL2L13')('GAB4')

22q11.21

22q11.1

Type of geneprotein-codingprotein-coding
Descriptionbcl-2-like protein 13BCL2-like 13 (apoptosis facilitator)GRB2-associated-binding protein 4GRB2-associated binder 2-like proteinGRB2-associated binder 4growth factor receptor bound protein 2-associated protein 4
Modification date2020031320200313
UniProtAcc.

Q2WGN9

Ensembl transtripts involved in fusion geneENST00000317582, ENST00000355028, 
ENST00000399782, ENST00000418951, 
ENST00000493680, ENST00000538149, 
ENST00000337612, ENST00000543133, 
ENST00000485631, 
Fusion gene scores* DoF score17 X 18 X 10=30602 X 3 X 2=12
# samples 233
** MAII scorelog2(23/3060*10)=-3.73382588663564
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(3/12*10)=1.32192809488736
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: BCL2L13 [Title/Abstract] AND GAB4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBCL2L13(18138598)-GAB4(17446158), # samples:4
Anticipated loss of major functional domain due to fusion event.BCL2L13-GAB4 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BCL2L13-GAB4 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BCL2L13-GAB4 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BCL2L13-GAB4 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across BCL2L13 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across GAB4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-HI-7168-01ABCL2L13chr22

18138597

+GAB4chr22

17446157

-
ChimerDB4PRADTCGA-HI-7168-01ABCL2L13chr22

18138598

-GAB4chr22

17446158

-
ChimerDB4PRADTCGA-HI-7168-01ABCL2L13chr22

18138598

+GAB4chr22

17446158

-
ChimerDB4PRADTCGA-HI-7168BCL2L13chr22

18138598

+GAB4chr22

17446158

-


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Fusion Gene ORF analysis for BCL2L13-GAB4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000317582ENST00000523144BCL2L13chr22

18138597

+GAB4chr22

17446157

-
5CDS-intronENST00000317582ENST00000523144BCL2L13chr22

18138598

+GAB4chr22

17446158

-
5CDS-intronENST00000355028ENST00000523144BCL2L13chr22

18138597

+GAB4chr22

17446157

-
5CDS-intronENST00000355028ENST00000523144BCL2L13chr22

18138598

+GAB4chr22

17446158

-
5CDS-intronENST00000399782ENST00000523144BCL2L13chr22

18138597

+GAB4chr22

17446157

-
5CDS-intronENST00000399782ENST00000523144BCL2L13chr22

18138598

+GAB4chr22

17446158

-
5CDS-intronENST00000418951ENST00000523144BCL2L13chr22

18138597

+GAB4chr22

17446157

-
5CDS-intronENST00000418951ENST00000523144BCL2L13chr22

18138598

+GAB4chr22

17446158

-
5CDS-intronENST00000493680ENST00000523144BCL2L13chr22

18138597

+GAB4chr22

17446157

-
5CDS-intronENST00000493680ENST00000523144BCL2L13chr22

18138598

+GAB4chr22

17446158

-
5CDS-intronENST00000538149ENST00000523144BCL2L13chr22

18138597

+GAB4chr22

17446157

-
5CDS-intronENST00000538149ENST00000523144BCL2L13chr22

18138598

+GAB4chr22

17446158

-
5UTR-3CDSENST00000337612ENST00000400588BCL2L13chr22

18138597

+GAB4chr22

17446157

-
5UTR-3CDSENST00000337612ENST00000400588BCL2L13chr22

18138598

+GAB4chr22

17446158

-
5UTR-3CDSENST00000543133ENST00000400588BCL2L13chr22

18138597

+GAB4chr22

17446157

-
5UTR-3CDSENST00000543133ENST00000400588BCL2L13chr22

18138598

+GAB4chr22

17446158

-
5UTR-intronENST00000337612ENST00000523144BCL2L13chr22

18138597

+GAB4chr22

17446157

-
5UTR-intronENST00000337612ENST00000523144BCL2L13chr22

18138598

+GAB4chr22

17446158

-
5UTR-intronENST00000543133ENST00000523144BCL2L13chr22

18138597

+GAB4chr22

17446157

-
5UTR-intronENST00000543133ENST00000523144BCL2L13chr22

18138598

+GAB4chr22

17446158

-
Frame-shiftENST00000538149ENST00000400588BCL2L13chr22

18138597

+GAB4chr22

17446157

-
Frame-shiftENST00000538149ENST00000400588BCL2L13chr22

18138598

+GAB4chr22

17446158

-
In-frameENST00000317582ENST00000400588BCL2L13chr22

18138597

+GAB4chr22

17446157

-
In-frameENST00000317582ENST00000400588BCL2L13chr22

18138598

+GAB4chr22

17446158

-
In-frameENST00000355028ENST00000400588BCL2L13chr22

18138597

+GAB4chr22

17446157

-
In-frameENST00000355028ENST00000400588BCL2L13chr22

18138598

+GAB4chr22

17446158

-
In-frameENST00000399782ENST00000400588BCL2L13chr22

18138597

+GAB4chr22

17446157

-
In-frameENST00000399782ENST00000400588BCL2L13chr22

18138598

+GAB4chr22

17446158

-
In-frameENST00000418951ENST00000400588BCL2L13chr22

18138597

+GAB4chr22

17446157

-
In-frameENST00000418951ENST00000400588BCL2L13chr22

18138598

+GAB4chr22

17446158

-
In-frameENST00000493680ENST00000400588BCL2L13chr22

18138597

+GAB4chr22

17446157

-
In-frameENST00000493680ENST00000400588BCL2L13chr22

18138598

+GAB4chr22

17446158

-
intron-3CDSENST00000485631ENST00000400588BCL2L13chr22

18138597

+GAB4chr22

17446157

-
intron-3CDSENST00000485631ENST00000400588BCL2L13chr22

18138598

+GAB4chr22

17446158

-
intron-intronENST00000485631ENST00000523144BCL2L13chr22

18138597

+GAB4chr22

17446157

-
intron-intronENST00000485631ENST00000523144BCL2L13chr22

18138598

+GAB4chr22

17446158

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000399782BCL2L13chr2218138598+ENST00000400588GAB4chr2217446158-20948607391296185
ENST00000317582BCL2L13chr2218138598+ENST00000400588GAB4chr2217446158-1702468347904185
ENST00000493680BCL2L13chr2218138598+ENST00000400588GAB4chr2217446158-1520286165722185
ENST00000355028BCL2L13chr2218138598+ENST00000400588GAB4chr2217446158-1481247126683185
ENST00000418951BCL2L13chr2218138598+ENST00000400588GAB4chr2217446158-13551210557185
ENST00000399782BCL2L13chr2218138597+ENST00000400588GAB4chr2217446157-20948607391296185
ENST00000317582BCL2L13chr2218138597+ENST00000400588GAB4chr2217446157-1702468347904185
ENST00000493680BCL2L13chr2218138597+ENST00000400588GAB4chr2217446157-1520286165722185
ENST00000355028BCL2L13chr2218138597+ENST00000400588GAB4chr2217446157-1481247126683185
ENST00000418951BCL2L13chr2218138597+ENST00000400588GAB4chr2217446157-13551210557185

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000399782ENST00000400588BCL2L13chr2218138598+GAB4chr2217446158-0.0112577270.98874223
ENST00000317582ENST00000400588BCL2L13chr2218138598+GAB4chr2217446158-0.0094223440.9905777
ENST00000493680ENST00000400588BCL2L13chr2218138598+GAB4chr2217446158-0.0092809910.990719
ENST00000355028ENST00000400588BCL2L13chr2218138598+GAB4chr2217446158-0.011153870.9888461
ENST00000418951ENST00000400588BCL2L13chr2218138598+GAB4chr2217446158-0.0135649110.98643506
ENST00000399782ENST00000400588BCL2L13chr2218138597+GAB4chr2217446157-0.0112577270.98874223
ENST00000317582ENST00000400588BCL2L13chr2218138597+GAB4chr2217446157-0.0094223440.9905777
ENST00000493680ENST00000400588BCL2L13chr2218138597+GAB4chr2217446157-0.0092809910.990719
ENST00000355028ENST00000400588BCL2L13chr2218138597+GAB4chr2217446157-0.011153870.9888461
ENST00000418951ENST00000400588BCL2L13chr2218138597+GAB4chr2217446157-0.0135649110.98643506

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Fusion Genomic Features for BCL2L13-GAB4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for BCL2L13-GAB4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:18138598/chr22:17446158)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.GAB4

Q2WGN9

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000317582+2714_3040486.0MotifNote=BH4
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000399782+3714_3040202.0MotifNote=BH4
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000493680+2614_3040202.0MotifNote=BH4
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000317582+2714_3040486.0MotifNote=BH4
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000399782+3714_3040202.0MotifNote=BH4
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000493680+2614_3040202.0MotifNote=BH4

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000317582+27207_21240486.0Compositional biasNote=Poly-Glu
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000317582+27311_42440486.0Compositional biasNote=Glu-rich
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000337612+25207_2120324.0Compositional biasNote=Poly-Glu
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000337612+25311_4240324.0Compositional biasNote=Glu-rich
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000399782+37207_21240202.0Compositional biasNote=Poly-Glu
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000399782+37311_42440202.0Compositional biasNote=Glu-rich
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000493680+26207_21240202.0Compositional biasNote=Poly-Glu
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000493680+26311_42440202.0Compositional biasNote=Glu-rich
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000543133+26207_2120324.0Compositional biasNote=Poly-Glu
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000543133+26311_4240324.0Compositional biasNote=Glu-rich
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000317582+27207_21240486.0Compositional biasNote=Poly-Glu
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000317582+27311_42440486.0Compositional biasNote=Glu-rich
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000337612+25207_2120324.0Compositional biasNote=Poly-Glu
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000337612+25311_4240324.0Compositional biasNote=Glu-rich
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000399782+37207_21240202.0Compositional biasNote=Poly-Glu
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000399782+37311_42440202.0Compositional biasNote=Glu-rich
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000493680+26207_21240202.0Compositional biasNote=Poly-Glu
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000493680+26311_42440202.0Compositional biasNote=Glu-rich
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000543133+26207_2120324.0Compositional biasNote=Poly-Glu
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000543133+26311_4240324.0Compositional biasNote=Glu-rich
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000317582+27100_11640486.0MotifNote=BH3
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000317582+27147_15740486.0MotifNote=BH1
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000317582+27193_20640486.0MotifNote=BH2
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000337612+25100_1160324.0MotifNote=BH3
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000337612+25147_1570324.0MotifNote=BH1
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000337612+2514_300324.0MotifNote=BH4
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000337612+25193_2060324.0MotifNote=BH2
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000399782+37100_11640202.0MotifNote=BH3
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000399782+37147_15740202.0MotifNote=BH1
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000399782+37193_20640202.0MotifNote=BH2
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000493680+26100_11640202.0MotifNote=BH3
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000493680+26147_15740202.0MotifNote=BH1
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000493680+26193_20640202.0MotifNote=BH2
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000543133+26100_1160324.0MotifNote=BH3
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000543133+26147_1570324.0MotifNote=BH1
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000543133+2614_300324.0MotifNote=BH4
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000543133+26193_2060324.0MotifNote=BH2
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000317582+27100_11640486.0MotifNote=BH3
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000317582+27147_15740486.0MotifNote=BH1
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000317582+27193_20640486.0MotifNote=BH2
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000337612+25100_1160324.0MotifNote=BH3
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000337612+25147_1570324.0MotifNote=BH1
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000337612+2514_300324.0MotifNote=BH4
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000337612+25193_2060324.0MotifNote=BH2
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000399782+37100_11640202.0MotifNote=BH3
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000399782+37147_15740202.0MotifNote=BH1
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000399782+37193_20640202.0MotifNote=BH2
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000493680+26100_11640202.0MotifNote=BH3
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000493680+26147_15740202.0MotifNote=BH1
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000493680+26193_20640202.0MotifNote=BH2
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000543133+26100_1160324.0MotifNote=BH3
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000543133+26147_1570324.0MotifNote=BH1
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000543133+2614_300324.0MotifNote=BH4
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000543133+26193_2060324.0MotifNote=BH2
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000317582+27246_25640486.0RepeatNote=A
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000317582+27261_27140486.0RepeatNote=A%3B approximate
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000317582+27425_44140486.0RepeatNote=B
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000317582+27443_45940486.0RepeatNote=B%3B approximate
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000337612+25246_2560324.0RepeatNote=A
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000337612+25261_2710324.0RepeatNote=A%3B approximate
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000337612+25425_4410324.0RepeatNote=B
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000337612+25443_4590324.0RepeatNote=B%3B approximate
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000399782+37246_25640202.0RepeatNote=A
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000399782+37261_27140202.0RepeatNote=A%3B approximate
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000399782+37425_44140202.0RepeatNote=B
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000399782+37443_45940202.0RepeatNote=B%3B approximate
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000493680+26246_25640202.0RepeatNote=A
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000493680+26261_27140202.0RepeatNote=A%3B approximate
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000493680+26425_44140202.0RepeatNote=B
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000493680+26443_45940202.0RepeatNote=B%3B approximate
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000543133+26246_2560324.0RepeatNote=A
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000543133+26261_2710324.0RepeatNote=A%3B approximate
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000543133+26425_4410324.0RepeatNote=B
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000543133+26443_4590324.0RepeatNote=B%3B approximate
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000317582+27246_25640486.0RepeatNote=A
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000317582+27261_27140486.0RepeatNote=A%3B approximate
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000317582+27425_44140486.0RepeatNote=B
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000317582+27443_45940486.0RepeatNote=B%3B approximate
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000337612+25246_2560324.0RepeatNote=A
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000337612+25261_2710324.0RepeatNote=A%3B approximate
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000337612+25425_4410324.0RepeatNote=B
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000337612+25443_4590324.0RepeatNote=B%3B approximate
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000399782+37246_25640202.0RepeatNote=A
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000399782+37261_27140202.0RepeatNote=A%3B approximate
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000399782+37425_44140202.0RepeatNote=B
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000399782+37443_45940202.0RepeatNote=B%3B approximate
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000493680+26246_25640202.0RepeatNote=A
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000493680+26261_27140202.0RepeatNote=A%3B approximate
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000493680+26425_44140202.0RepeatNote=B
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000493680+26443_45940202.0RepeatNote=B%3B approximate
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000543133+26246_2560324.0RepeatNote=A
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000543133+26261_2710324.0RepeatNote=A%3B approximate
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000543133+26425_4410324.0RepeatNote=B
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000543133+26443_4590324.0RepeatNote=B%3B approximate
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000317582+27460_48040486.0TransmembraneHelical
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000337612+25460_4800324.0TransmembraneHelical
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000399782+37460_48040202.0TransmembraneHelical
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000493680+26460_48040202.0TransmembraneHelical
HgeneBCL2L13chr22:18138597chr22:17446157ENST00000543133+26460_4800324.0TransmembraneHelical
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000317582+27460_48040486.0TransmembraneHelical
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000337612+25460_4800324.0TransmembraneHelical
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000399782+37460_48040202.0TransmembraneHelical
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000493680+26460_48040202.0TransmembraneHelical
HgeneBCL2L13chr22:18138598chr22:17446158ENST00000543133+26460_4800324.0TransmembraneHelical
TgeneGAB4chr22:18138597chr22:17446157ENST0000040058851039_152429575.0DomainPH
TgeneGAB4chr22:18138598chr22:17446158ENST0000040058851039_152429575.0DomainPH


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Fusion Gene Sequence for BCL2L13-GAB4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>9355_9355_1_BCL2L13-GAB4_BCL2L13_chr22_18138597_ENST00000317582_GAB4_chr22_17446157_ENST00000400588_length(transcript)=1702nt_BP=468nt
AGATTTGGGCGGGCTAGGAGGGTTTGGGTCTTCAGGTCACATCTGGACGGAGAGACCTCCGGGGCCTCCGTTGGTCGGTCCTTCCGCTCC
GGATACCGTTCCGGATGTCAGGTAGTTCAGGTCCCGCCCCGACGCCGGCCGTGACGAAGGCACGCCGGGGTGACCTCACCCTCCAACATG
GCGGCGGCGGTAGATTAGGGCCGCGGGTCGGAGCACTCACCGCCGCTGGGGGACCCTGTCGGAAGCAACTGCCGCCGCCGCCTCTTTCAT
CTCTTCTGGGGCAGGGGCCAGGGCCAGGTTTTACACATCCATAAGTAGACCTTTTTGGAGCCTCACCAGCCAATTCAATGGCGTCCTCTT
CTACTGTGCCTCTGGGATTTCACTATGAAACAAAGTATGTTGTTCTCAGCTACTTGGGACTCCTCTCTCAAGAGAAGCTGCAAGAGCAAC
ATCTTTCCTCACCCCAAGCCAACCCAACACCGCCCAACCTGAGAAACAACAGGGTCATCAATGAGCTCTCCTTCAAGCCACCTGTCACAG
AGCCCTGGTCTGGGACCAGCCACACCTTTGACTCCAGCTCCTCCCAACACCCCATCTCCACGCAGAGCATCACCAACACAGACTCAGAAG
ACAGTGGAGAGAGGTATCTTTTCCCGAACCCGGCATCTGCATTTCCTGTTTCCGGTGGCACCAGCAGTTCAGCCCCGCCGAGGAGCACTG
GTAACATCCACTACGCGGCCCTGGACTTCCAGCCGAGCAAGCCATCCATAGGCTCTGTCACGTCCGGCAAGAAGGTGGACTATGTCCAGG
TGGATCTGGAGAAGACCCAGGCCCTGCAGAAGACCATGCATGAACAGATGTGCCTGCGGCAGTCCTCAGAGCCTCCCAGGGGCGCCAAGC
TGTGACTCGGGCCACCAAAACCAGAGTGGGGCCAGGACAGTGCCTCAGAGCTGCTCCGCCACACTCTAAAGCTCTGTAATATCAGGGACC
GCATCCCTTACATAGAGAGCAGAGGCCTGATCAATATACATCCTTTGCCTGCTTGGGGCCCACCTGTGCCTTTGGCTGGCCATGGTCCCC
ACCTTCACCCCCTTGCTAGGAGCAGTTGCCAGCAAGCATCCTCAGTCTCTTCCTGCCCCTCAGACCCGGGCTCCCAACAGATTTCCACTC
TCACACTTACTCATGGTCCTCAGCCTCTTCCTTCTAGCCTCTGGGCTGTTTCCCTCAATCCTGGAACATGAGGAGCTACCTTGCTGACCC
GGGGACCCAAGGCCCACAGGCCACAGTGGACATGGACCTTTTCAGCCCTGGCATTTTTTGGTCAGGGGAGAGGCAAGGCCATCAAACGTT
GGAATAGTTGAGAAGGAAGGTTAAAGGTGGTCTTGAGAAGCAAAGGAATTAGATCCTTAGACCAGCAGGGCAGCTGATACCTGCAAGGGC
TCCCACTTTCAGACTGAGGCCAGAGTATGGCAGCTGCTCCCGGGTGGGAGAGGCAGAGAGGGAAGGGCAAAAGGAAGGGAAAACATGAAG
ACGAACAGCCGAAAGCCACAAGAAGCAGGGCTGGAGCTCCAGAGACTGGGGTGACAAGGACCAGGGTCAGGGCCCCAGAAATCCGGAGCT

>9355_9355_1_BCL2L13-GAB4_BCL2L13_chr22_18138597_ENST00000317582_GAB4_chr22_17446157_ENST00000400588_length(amino acids)=185AA_BP=40
MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQANPTPPNLRNNRVINELSFKPPVTEPWSGTSHTFDSSSSQHPISTQSITN
TDSEDSGERYLFPNPASAFPVSGGTSSSAPPRSTGNIHYAALDFQPSKPSIGSVTSGKKVDYVQVDLEKTQALQKTMHEQMCLRQSSEPP

--------------------------------------------------------------
>9355_9355_2_BCL2L13-GAB4_BCL2L13_chr22_18138597_ENST00000355028_GAB4_chr22_17446157_ENST00000400588_length(transcript)=1481nt_BP=247nt
GCCGCTGGGGGACCCTGTCGGAAGCAACTGCCGCCGCCGCCTCTTTCATCTCTTCTGGGGCAGGGGCCAGGGCCAGGTTTTACACATCCA
TAAGTAGACCTTTTTGGAGCCTCACCAGCCAATTCAATGGCGTCCTCTTCTACTGTGCCTCTGGGATTTCACTATGAAACAAAGTATGTT
GTTCTCAGCTACTTGGGACTCCTCTCTCAAGAGAAGCTGCAAGAGCAACATCTTTCCTCACCCCAAGCCAACCCAACACCGCCCAACCTG
AGAAACAACAGGGTCATCAATGAGCTCTCCTTCAAGCCACCTGTCACAGAGCCCTGGTCTGGGACCAGCCACACCTTTGACTCCAGCTCC
TCCCAACACCCCATCTCCACGCAGAGCATCACCAACACAGACTCAGAAGACAGTGGAGAGAGGTATCTTTTCCCGAACCCGGCATCTGCA
TTTCCTGTTTCCGGTGGCACCAGCAGTTCAGCCCCGCCGAGGAGCACTGGTAACATCCACTACGCGGCCCTGGACTTCCAGCCGAGCAAG
CCATCCATAGGCTCTGTCACGTCCGGCAAGAAGGTGGACTATGTCCAGGTGGATCTGGAGAAGACCCAGGCCCTGCAGAAGACCATGCAT
GAACAGATGTGCCTGCGGCAGTCCTCAGAGCCTCCCAGGGGCGCCAAGCTGTGACTCGGGCCACCAAAACCAGAGTGGGGCCAGGACAGT
GCCTCAGAGCTGCTCCGCCACACTCTAAAGCTCTGTAATATCAGGGACCGCATCCCTTACATAGAGAGCAGAGGCCTGATCAATATACAT
CCTTTGCCTGCTTGGGGCCCACCTGTGCCTTTGGCTGGCCATGGTCCCCACCTTCACCCCCTTGCTAGGAGCAGTTGCCAGCAAGCATCC
TCAGTCTCTTCCTGCCCCTCAGACCCGGGCTCCCAACAGATTTCCACTCTCACACTTACTCATGGTCCTCAGCCTCTTCCTTCTAGCCTC
TGGGCTGTTTCCCTCAATCCTGGAACATGAGGAGCTACCTTGCTGACCCGGGGACCCAAGGCCCACAGGCCACAGTGGACATGGACCTTT
TCAGCCCTGGCATTTTTTGGTCAGGGGAGAGGCAAGGCCATCAAACGTTGGAATAGTTGAGAAGGAAGGTTAAAGGTGGTCTTGAGAAGC
AAAGGAATTAGATCCTTAGACCAGCAGGGCAGCTGATACCTGCAAGGGCTCCCACTTTCAGACTGAGGCCAGAGTATGGCAGCTGCTCCC
GGGTGGGAGAGGCAGAGAGGGAAGGGCAAAAGGAAGGGAAAACATGAAGACGAACAGCCGAAAGCCACAAGAAGCAGGGCTGGAGCTCCA
GAGACTGGGGTGACAAGGACCAGGGTCAGGGCCCCAGAAATCCGGAGCTGCAGGCTGGCTCTGCTGCTCTTTGCTGATGCCCCTTGGGGG

>9355_9355_2_BCL2L13-GAB4_BCL2L13_chr22_18138597_ENST00000355028_GAB4_chr22_17446157_ENST00000400588_length(amino acids)=185AA_BP=40
MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQANPTPPNLRNNRVINELSFKPPVTEPWSGTSHTFDSSSSQHPISTQSITN
TDSEDSGERYLFPNPASAFPVSGGTSSSAPPRSTGNIHYAALDFQPSKPSIGSVTSGKKVDYVQVDLEKTQALQKTMHEQMCLRQSSEPP

--------------------------------------------------------------
>9355_9355_3_BCL2L13-GAB4_BCL2L13_chr22_18138597_ENST00000399782_GAB4_chr22_17446157_ENST00000400588_length(transcript)=2094nt_BP=860nt
TCCTAAACTGGGATCTTGGGTAGGAGGAAGAAAAGATAAGGAGTTCCTCTATCTGAAATTAGTCGGGCTGTTTTGAGGAGTACTGGTTAG
ATACCTTCCGATACTCCTCCAAAGAACTCTCGGATTCAAGTAAACAAACATCCATTAATACAAGTTAAGTATGTTCCAGGCGCTGTGTGT
TCCAGGTACTGTTAACAAAAGCGGGTTACTAGTTAAGACTTCCTTCATGCCCTGGCGCCTCTGCTCAGCCAGTTCCCTTCGCCTAGGAGG
ACCTCTCTACACCACCCCGCTATATTCCCTCCCCGGAATTCCTTCCCAACCTTCAAGGACCATCTGCCCCAACTAGTGGCGAACATCGAG
GCTGTCGTGACTGTGTAGATACTTATTTGACCTGCTCCCTTGGCAAACACTTGAAACGCAATACATGTTTGTGGAACTGAACATAGCCTG
TGCATGCAGCAAGGCTTCTTTCCCTGGAATCGCCTGCCCTTCCTCCAACACAGCGACCAGCCGGTCAGAATCCCAACCCCTCGACTCCGG
AAATGATCTGAGAGACGGAACTTCCGAACGTCGCAATCAGATTTGGGCGGGCTAGGAGGGTTTGGGTCTTCAGGTCACATCTGGACGGAG
AGACCTCCGGGGCCTCCGTTGGTCGGTCCTTCCGCTCCGGATACCGTTCCGGATGTCAGGTTTTACACATCCATAAGTAGACCTTTTTGG
AGCCTCACCAGCCAATTCAATGGCGTCCTCTTCTACTGTGCCTCTGGGATTTCACTATGAAACAAAGTATGTTGTTCTCAGCTACTTGGG
ACTCCTCTCTCAAGAGAAGCTGCAAGAGCAACATCTTTCCTCACCCCAAGCCAACCCAACACCGCCCAACCTGAGAAACAACAGGGTCAT
CAATGAGCTCTCCTTCAAGCCACCTGTCACAGAGCCCTGGTCTGGGACCAGCCACACCTTTGACTCCAGCTCCTCCCAACACCCCATCTC
CACGCAGAGCATCACCAACACAGACTCAGAAGACAGTGGAGAGAGGTATCTTTTCCCGAACCCGGCATCTGCATTTCCTGTTTCCGGTGG
CACCAGCAGTTCAGCCCCGCCGAGGAGCACTGGTAACATCCACTACGCGGCCCTGGACTTCCAGCCGAGCAAGCCATCCATAGGCTCTGT
CACGTCCGGCAAGAAGGTGGACTATGTCCAGGTGGATCTGGAGAAGACCCAGGCCCTGCAGAAGACCATGCATGAACAGATGTGCCTGCG
GCAGTCCTCAGAGCCTCCCAGGGGCGCCAAGCTGTGACTCGGGCCACCAAAACCAGAGTGGGGCCAGGACAGTGCCTCAGAGCTGCTCCG
CCACACTCTAAAGCTCTGTAATATCAGGGACCGCATCCCTTACATAGAGAGCAGAGGCCTGATCAATATACATCCTTTGCCTGCTTGGGG
CCCACCTGTGCCTTTGGCTGGCCATGGTCCCCACCTTCACCCCCTTGCTAGGAGCAGTTGCCAGCAAGCATCCTCAGTCTCTTCCTGCCC
CTCAGACCCGGGCTCCCAACAGATTTCCACTCTCACACTTACTCATGGTCCTCAGCCTCTTCCTTCTAGCCTCTGGGCTGTTTCCCTCAA
TCCTGGAACATGAGGAGCTACCTTGCTGACCCGGGGACCCAAGGCCCACAGGCCACAGTGGACATGGACCTTTTCAGCCCTGGCATTTTT
TGGTCAGGGGAGAGGCAAGGCCATCAAACGTTGGAATAGTTGAGAAGGAAGGTTAAAGGTGGTCTTGAGAAGCAAAGGAATTAGATCCTT
AGACCAGCAGGGCAGCTGATACCTGCAAGGGCTCCCACTTTCAGACTGAGGCCAGAGTATGGCAGCTGCTCCCGGGTGGGAGAGGCAGAG
AGGGAAGGGCAAAAGGAAGGGAAAACATGAAGACGAACAGCCGAAAGCCACAAGAAGCAGGGCTGGAGCTCCAGAGACTGGGGTGACAAG
GACCAGGGTCAGGGCCCCAGAAATCCGGAGCTGCAGGCTGGCTCTGCTGCTCTTTGCTGATGCCCCTTGGGGGGCCCTTGCCTGCCTAAG

>9355_9355_3_BCL2L13-GAB4_BCL2L13_chr22_18138597_ENST00000399782_GAB4_chr22_17446157_ENST00000400588_length(amino acids)=185AA_BP=40
MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQANPTPPNLRNNRVINELSFKPPVTEPWSGTSHTFDSSSSQHPISTQSITN
TDSEDSGERYLFPNPASAFPVSGGTSSSAPPRSTGNIHYAALDFQPSKPSIGSVTSGKKVDYVQVDLEKTQALQKTMHEQMCLRQSSEPP

--------------------------------------------------------------
>9355_9355_4_BCL2L13-GAB4_BCL2L13_chr22_18138597_ENST00000418951_GAB4_chr22_17446157_ENST00000400588_length(transcript)=1355nt_BP=121nt
ATGGCGTCCTCTTCTACTGTGCCTCTGGGATTTCACTATGAAACAAAGTATGTTGTTCTCAGCTACTTGGGACTCCTCTCTCAAGAGAAG
CTGCAAGAGCAACATCTTTCCTCACCCCAAGCCAACCCAACACCGCCCAACCTGAGAAACAACAGGGTCATCAATGAGCTCTCCTTCAAG
CCACCTGTCACAGAGCCCTGGTCTGGGACCAGCCACACCTTTGACTCCAGCTCCTCCCAACACCCCATCTCCACGCAGAGCATCACCAAC
ACAGACTCAGAAGACAGTGGAGAGAGGTATCTTTTCCCGAACCCGGCATCTGCATTTCCTGTTTCCGGTGGCACCAGCAGTTCAGCCCCG
CCGAGGAGCACTGGTAACATCCACTACGCGGCCCTGGACTTCCAGCCGAGCAAGCCATCCATAGGCTCTGTCACGTCCGGCAAGAAGGTG
GACTATGTCCAGGTGGATCTGGAGAAGACCCAGGCCCTGCAGAAGACCATGCATGAACAGATGTGCCTGCGGCAGTCCTCAGAGCCTCCC
AGGGGCGCCAAGCTGTGACTCGGGCCACCAAAACCAGAGTGGGGCCAGGACAGTGCCTCAGAGCTGCTCCGCCACACTCTAAAGCTCTGT
AATATCAGGGACCGCATCCCTTACATAGAGAGCAGAGGCCTGATCAATATACATCCTTTGCCTGCTTGGGGCCCACCTGTGCCTTTGGCT
GGCCATGGTCCCCACCTTCACCCCCTTGCTAGGAGCAGTTGCCAGCAAGCATCCTCAGTCTCTTCCTGCCCCTCAGACCCGGGCTCCCAA
CAGATTTCCACTCTCACACTTACTCATGGTCCTCAGCCTCTTCCTTCTAGCCTCTGGGCTGTTTCCCTCAATCCTGGAACATGAGGAGCT
ACCTTGCTGACCCGGGGACCCAAGGCCCACAGGCCACAGTGGACATGGACCTTTTCAGCCCTGGCATTTTTTGGTCAGGGGAGAGGCAAG
GCCATCAAACGTTGGAATAGTTGAGAAGGAAGGTTAAAGGTGGTCTTGAGAAGCAAAGGAATTAGATCCTTAGACCAGCAGGGCAGCTGA
TACCTGCAAGGGCTCCCACTTTCAGACTGAGGCCAGAGTATGGCAGCTGCTCCCGGGTGGGAGAGGCAGAGAGGGAAGGGCAAAAGGAAG
GGAAAACATGAAGACGAACAGCCGAAAGCCACAAGAAGCAGGGCTGGAGCTCCAGAGACTGGGGTGACAAGGACCAGGGTCAGGGCCCCA
GAAATCCGGAGCTGCAGGCTGGCTCTGCTGCTCTTTGCTGATGCCCCTTGGGGGGCCCTTGCCTGCCTAAGAAGGCTTGATCTGAGCTGG

>9355_9355_4_BCL2L13-GAB4_BCL2L13_chr22_18138597_ENST00000418951_GAB4_chr22_17446157_ENST00000400588_length(amino acids)=185AA_BP=40
MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQANPTPPNLRNNRVINELSFKPPVTEPWSGTSHTFDSSSSQHPISTQSITN
TDSEDSGERYLFPNPASAFPVSGGTSSSAPPRSTGNIHYAALDFQPSKPSIGSVTSGKKVDYVQVDLEKTQALQKTMHEQMCLRQSSEPP

--------------------------------------------------------------
>9355_9355_5_BCL2L13-GAB4_BCL2L13_chr22_18138597_ENST00000493680_GAB4_chr22_17446157_ENST00000400588_length(transcript)=1520nt_BP=286nt
GGCGGCGGTAGATTAGGGCCGCGGGTCGGAGCACTCACCGCCGCTGGGGGACCCTGTCGGAAGCAACTGCCGCCGCCGCCTCTTTCATCT
CTTCTGGGGCAGGGGCCAGGGCCAGGTTTTACACATCCATAAGTAGACCTTTTTGGAGCCTCACCAGCCAATTCAATGGCGTCCTCTTCT
ACTGTGCCTCTGGGATTTCACTATGAAACAAAGTATGTTGTTCTCAGCTACTTGGGACTCCTCTCTCAAGAGAAGCTGCAAGAGCAACAT
CTTTCCTCACCCCAAGCCAACCCAACACCGCCCAACCTGAGAAACAACAGGGTCATCAATGAGCTCTCCTTCAAGCCACCTGTCACAGAG
CCCTGGTCTGGGACCAGCCACACCTTTGACTCCAGCTCCTCCCAACACCCCATCTCCACGCAGAGCATCACCAACACAGACTCAGAAGAC
AGTGGAGAGAGGTATCTTTTCCCGAACCCGGCATCTGCATTTCCTGTTTCCGGTGGCACCAGCAGTTCAGCCCCGCCGAGGAGCACTGGT
AACATCCACTACGCGGCCCTGGACTTCCAGCCGAGCAAGCCATCCATAGGCTCTGTCACGTCCGGCAAGAAGGTGGACTATGTCCAGGTG
GATCTGGAGAAGACCCAGGCCCTGCAGAAGACCATGCATGAACAGATGTGCCTGCGGCAGTCCTCAGAGCCTCCCAGGGGCGCCAAGCTG
TGACTCGGGCCACCAAAACCAGAGTGGGGCCAGGACAGTGCCTCAGAGCTGCTCCGCCACACTCTAAAGCTCTGTAATATCAGGGACCGC
ATCCCTTACATAGAGAGCAGAGGCCTGATCAATATACATCCTTTGCCTGCTTGGGGCCCACCTGTGCCTTTGGCTGGCCATGGTCCCCAC
CTTCACCCCCTTGCTAGGAGCAGTTGCCAGCAAGCATCCTCAGTCTCTTCCTGCCCCTCAGACCCGGGCTCCCAACAGATTTCCACTCTC
ACACTTACTCATGGTCCTCAGCCTCTTCCTTCTAGCCTCTGGGCTGTTTCCCTCAATCCTGGAACATGAGGAGCTACCTTGCTGACCCGG
GGACCCAAGGCCCACAGGCCACAGTGGACATGGACCTTTTCAGCCCTGGCATTTTTTGGTCAGGGGAGAGGCAAGGCCATCAAACGTTGG
AATAGTTGAGAAGGAAGGTTAAAGGTGGTCTTGAGAAGCAAAGGAATTAGATCCTTAGACCAGCAGGGCAGCTGATACCTGCAAGGGCTC
CCACTTTCAGACTGAGGCCAGAGTATGGCAGCTGCTCCCGGGTGGGAGAGGCAGAGAGGGAAGGGCAAAAGGAAGGGAAAACATGAAGAC
GAACAGCCGAAAGCCACAAGAAGCAGGGCTGGAGCTCCAGAGACTGGGGTGACAAGGACCAGGGTCAGGGCCCCAGAAATCCGGAGCTGC

>9355_9355_5_BCL2L13-GAB4_BCL2L13_chr22_18138597_ENST00000493680_GAB4_chr22_17446157_ENST00000400588_length(amino acids)=185AA_BP=40
MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQANPTPPNLRNNRVINELSFKPPVTEPWSGTSHTFDSSSSQHPISTQSITN
TDSEDSGERYLFPNPASAFPVSGGTSSSAPPRSTGNIHYAALDFQPSKPSIGSVTSGKKVDYVQVDLEKTQALQKTMHEQMCLRQSSEPP

--------------------------------------------------------------
>9355_9355_6_BCL2L13-GAB4_BCL2L13_chr22_18138598_ENST00000317582_GAB4_chr22_17446158_ENST00000400588_length(transcript)=1702nt_BP=468nt
AGATTTGGGCGGGCTAGGAGGGTTTGGGTCTTCAGGTCACATCTGGACGGAGAGACCTCCGGGGCCTCCGTTGGTCGGTCCTTCCGCTCC
GGATACCGTTCCGGATGTCAGGTAGTTCAGGTCCCGCCCCGACGCCGGCCGTGACGAAGGCACGCCGGGGTGACCTCACCCTCCAACATG
GCGGCGGCGGTAGATTAGGGCCGCGGGTCGGAGCACTCACCGCCGCTGGGGGACCCTGTCGGAAGCAACTGCCGCCGCCGCCTCTTTCAT
CTCTTCTGGGGCAGGGGCCAGGGCCAGGTTTTACACATCCATAAGTAGACCTTTTTGGAGCCTCACCAGCCAATTCAATGGCGTCCTCTT
CTACTGTGCCTCTGGGATTTCACTATGAAACAAAGTATGTTGTTCTCAGCTACTTGGGACTCCTCTCTCAAGAGAAGCTGCAAGAGCAAC
ATCTTTCCTCACCCCAAGCCAACCCAACACCGCCCAACCTGAGAAACAACAGGGTCATCAATGAGCTCTCCTTCAAGCCACCTGTCACAG
AGCCCTGGTCTGGGACCAGCCACACCTTTGACTCCAGCTCCTCCCAACACCCCATCTCCACGCAGAGCATCACCAACACAGACTCAGAAG
ACAGTGGAGAGAGGTATCTTTTCCCGAACCCGGCATCTGCATTTCCTGTTTCCGGTGGCACCAGCAGTTCAGCCCCGCCGAGGAGCACTG
GTAACATCCACTACGCGGCCCTGGACTTCCAGCCGAGCAAGCCATCCATAGGCTCTGTCACGTCCGGCAAGAAGGTGGACTATGTCCAGG
TGGATCTGGAGAAGACCCAGGCCCTGCAGAAGACCATGCATGAACAGATGTGCCTGCGGCAGTCCTCAGAGCCTCCCAGGGGCGCCAAGC
TGTGACTCGGGCCACCAAAACCAGAGTGGGGCCAGGACAGTGCCTCAGAGCTGCTCCGCCACACTCTAAAGCTCTGTAATATCAGGGACC
GCATCCCTTACATAGAGAGCAGAGGCCTGATCAATATACATCCTTTGCCTGCTTGGGGCCCACCTGTGCCTTTGGCTGGCCATGGTCCCC
ACCTTCACCCCCTTGCTAGGAGCAGTTGCCAGCAAGCATCCTCAGTCTCTTCCTGCCCCTCAGACCCGGGCTCCCAACAGATTTCCACTC
TCACACTTACTCATGGTCCTCAGCCTCTTCCTTCTAGCCTCTGGGCTGTTTCCCTCAATCCTGGAACATGAGGAGCTACCTTGCTGACCC
GGGGACCCAAGGCCCACAGGCCACAGTGGACATGGACCTTTTCAGCCCTGGCATTTTTTGGTCAGGGGAGAGGCAAGGCCATCAAACGTT
GGAATAGTTGAGAAGGAAGGTTAAAGGTGGTCTTGAGAAGCAAAGGAATTAGATCCTTAGACCAGCAGGGCAGCTGATACCTGCAAGGGC
TCCCACTTTCAGACTGAGGCCAGAGTATGGCAGCTGCTCCCGGGTGGGAGAGGCAGAGAGGGAAGGGCAAAAGGAAGGGAAAACATGAAG
ACGAACAGCCGAAAGCCACAAGAAGCAGGGCTGGAGCTCCAGAGACTGGGGTGACAAGGACCAGGGTCAGGGCCCCAGAAATCCGGAGCT

>9355_9355_6_BCL2L13-GAB4_BCL2L13_chr22_18138598_ENST00000317582_GAB4_chr22_17446158_ENST00000400588_length(amino acids)=185AA_BP=40
MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQANPTPPNLRNNRVINELSFKPPVTEPWSGTSHTFDSSSSQHPISTQSITN
TDSEDSGERYLFPNPASAFPVSGGTSSSAPPRSTGNIHYAALDFQPSKPSIGSVTSGKKVDYVQVDLEKTQALQKTMHEQMCLRQSSEPP

--------------------------------------------------------------
>9355_9355_7_BCL2L13-GAB4_BCL2L13_chr22_18138598_ENST00000355028_GAB4_chr22_17446158_ENST00000400588_length(transcript)=1481nt_BP=247nt
GCCGCTGGGGGACCCTGTCGGAAGCAACTGCCGCCGCCGCCTCTTTCATCTCTTCTGGGGCAGGGGCCAGGGCCAGGTTTTACACATCCA
TAAGTAGACCTTTTTGGAGCCTCACCAGCCAATTCAATGGCGTCCTCTTCTACTGTGCCTCTGGGATTTCACTATGAAACAAAGTATGTT
GTTCTCAGCTACTTGGGACTCCTCTCTCAAGAGAAGCTGCAAGAGCAACATCTTTCCTCACCCCAAGCCAACCCAACACCGCCCAACCTG
AGAAACAACAGGGTCATCAATGAGCTCTCCTTCAAGCCACCTGTCACAGAGCCCTGGTCTGGGACCAGCCACACCTTTGACTCCAGCTCC
TCCCAACACCCCATCTCCACGCAGAGCATCACCAACACAGACTCAGAAGACAGTGGAGAGAGGTATCTTTTCCCGAACCCGGCATCTGCA
TTTCCTGTTTCCGGTGGCACCAGCAGTTCAGCCCCGCCGAGGAGCACTGGTAACATCCACTACGCGGCCCTGGACTTCCAGCCGAGCAAG
CCATCCATAGGCTCTGTCACGTCCGGCAAGAAGGTGGACTATGTCCAGGTGGATCTGGAGAAGACCCAGGCCCTGCAGAAGACCATGCAT
GAACAGATGTGCCTGCGGCAGTCCTCAGAGCCTCCCAGGGGCGCCAAGCTGTGACTCGGGCCACCAAAACCAGAGTGGGGCCAGGACAGT
GCCTCAGAGCTGCTCCGCCACACTCTAAAGCTCTGTAATATCAGGGACCGCATCCCTTACATAGAGAGCAGAGGCCTGATCAATATACAT
CCTTTGCCTGCTTGGGGCCCACCTGTGCCTTTGGCTGGCCATGGTCCCCACCTTCACCCCCTTGCTAGGAGCAGTTGCCAGCAAGCATCC
TCAGTCTCTTCCTGCCCCTCAGACCCGGGCTCCCAACAGATTTCCACTCTCACACTTACTCATGGTCCTCAGCCTCTTCCTTCTAGCCTC
TGGGCTGTTTCCCTCAATCCTGGAACATGAGGAGCTACCTTGCTGACCCGGGGACCCAAGGCCCACAGGCCACAGTGGACATGGACCTTT
TCAGCCCTGGCATTTTTTGGTCAGGGGAGAGGCAAGGCCATCAAACGTTGGAATAGTTGAGAAGGAAGGTTAAAGGTGGTCTTGAGAAGC
AAAGGAATTAGATCCTTAGACCAGCAGGGCAGCTGATACCTGCAAGGGCTCCCACTTTCAGACTGAGGCCAGAGTATGGCAGCTGCTCCC
GGGTGGGAGAGGCAGAGAGGGAAGGGCAAAAGGAAGGGAAAACATGAAGACGAACAGCCGAAAGCCACAAGAAGCAGGGCTGGAGCTCCA
GAGACTGGGGTGACAAGGACCAGGGTCAGGGCCCCAGAAATCCGGAGCTGCAGGCTGGCTCTGCTGCTCTTTGCTGATGCCCCTTGGGGG

>9355_9355_7_BCL2L13-GAB4_BCL2L13_chr22_18138598_ENST00000355028_GAB4_chr22_17446158_ENST00000400588_length(amino acids)=185AA_BP=40
MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQANPTPPNLRNNRVINELSFKPPVTEPWSGTSHTFDSSSSQHPISTQSITN
TDSEDSGERYLFPNPASAFPVSGGTSSSAPPRSTGNIHYAALDFQPSKPSIGSVTSGKKVDYVQVDLEKTQALQKTMHEQMCLRQSSEPP

--------------------------------------------------------------
>9355_9355_8_BCL2L13-GAB4_BCL2L13_chr22_18138598_ENST00000399782_GAB4_chr22_17446158_ENST00000400588_length(transcript)=2094nt_BP=860nt
TCCTAAACTGGGATCTTGGGTAGGAGGAAGAAAAGATAAGGAGTTCCTCTATCTGAAATTAGTCGGGCTGTTTTGAGGAGTACTGGTTAG
ATACCTTCCGATACTCCTCCAAAGAACTCTCGGATTCAAGTAAACAAACATCCATTAATACAAGTTAAGTATGTTCCAGGCGCTGTGTGT
TCCAGGTACTGTTAACAAAAGCGGGTTACTAGTTAAGACTTCCTTCATGCCCTGGCGCCTCTGCTCAGCCAGTTCCCTTCGCCTAGGAGG
ACCTCTCTACACCACCCCGCTATATTCCCTCCCCGGAATTCCTTCCCAACCTTCAAGGACCATCTGCCCCAACTAGTGGCGAACATCGAG
GCTGTCGTGACTGTGTAGATACTTATTTGACCTGCTCCCTTGGCAAACACTTGAAACGCAATACATGTTTGTGGAACTGAACATAGCCTG
TGCATGCAGCAAGGCTTCTTTCCCTGGAATCGCCTGCCCTTCCTCCAACACAGCGACCAGCCGGTCAGAATCCCAACCCCTCGACTCCGG
AAATGATCTGAGAGACGGAACTTCCGAACGTCGCAATCAGATTTGGGCGGGCTAGGAGGGTTTGGGTCTTCAGGTCACATCTGGACGGAG
AGACCTCCGGGGCCTCCGTTGGTCGGTCCTTCCGCTCCGGATACCGTTCCGGATGTCAGGTTTTACACATCCATAAGTAGACCTTTTTGG
AGCCTCACCAGCCAATTCAATGGCGTCCTCTTCTACTGTGCCTCTGGGATTTCACTATGAAACAAAGTATGTTGTTCTCAGCTACTTGGG
ACTCCTCTCTCAAGAGAAGCTGCAAGAGCAACATCTTTCCTCACCCCAAGCCAACCCAACACCGCCCAACCTGAGAAACAACAGGGTCAT
CAATGAGCTCTCCTTCAAGCCACCTGTCACAGAGCCCTGGTCTGGGACCAGCCACACCTTTGACTCCAGCTCCTCCCAACACCCCATCTC
CACGCAGAGCATCACCAACACAGACTCAGAAGACAGTGGAGAGAGGTATCTTTTCCCGAACCCGGCATCTGCATTTCCTGTTTCCGGTGG
CACCAGCAGTTCAGCCCCGCCGAGGAGCACTGGTAACATCCACTACGCGGCCCTGGACTTCCAGCCGAGCAAGCCATCCATAGGCTCTGT
CACGTCCGGCAAGAAGGTGGACTATGTCCAGGTGGATCTGGAGAAGACCCAGGCCCTGCAGAAGACCATGCATGAACAGATGTGCCTGCG
GCAGTCCTCAGAGCCTCCCAGGGGCGCCAAGCTGTGACTCGGGCCACCAAAACCAGAGTGGGGCCAGGACAGTGCCTCAGAGCTGCTCCG
CCACACTCTAAAGCTCTGTAATATCAGGGACCGCATCCCTTACATAGAGAGCAGAGGCCTGATCAATATACATCCTTTGCCTGCTTGGGG
CCCACCTGTGCCTTTGGCTGGCCATGGTCCCCACCTTCACCCCCTTGCTAGGAGCAGTTGCCAGCAAGCATCCTCAGTCTCTTCCTGCCC
CTCAGACCCGGGCTCCCAACAGATTTCCACTCTCACACTTACTCATGGTCCTCAGCCTCTTCCTTCTAGCCTCTGGGCTGTTTCCCTCAA
TCCTGGAACATGAGGAGCTACCTTGCTGACCCGGGGACCCAAGGCCCACAGGCCACAGTGGACATGGACCTTTTCAGCCCTGGCATTTTT
TGGTCAGGGGAGAGGCAAGGCCATCAAACGTTGGAATAGTTGAGAAGGAAGGTTAAAGGTGGTCTTGAGAAGCAAAGGAATTAGATCCTT
AGACCAGCAGGGCAGCTGATACCTGCAAGGGCTCCCACTTTCAGACTGAGGCCAGAGTATGGCAGCTGCTCCCGGGTGGGAGAGGCAGAG
AGGGAAGGGCAAAAGGAAGGGAAAACATGAAGACGAACAGCCGAAAGCCACAAGAAGCAGGGCTGGAGCTCCAGAGACTGGGGTGACAAG
GACCAGGGTCAGGGCCCCAGAAATCCGGAGCTGCAGGCTGGCTCTGCTGCTCTTTGCTGATGCCCCTTGGGGGGCCCTTGCCTGCCTAAG

>9355_9355_8_BCL2L13-GAB4_BCL2L13_chr22_18138598_ENST00000399782_GAB4_chr22_17446158_ENST00000400588_length(amino acids)=185AA_BP=40
MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQANPTPPNLRNNRVINELSFKPPVTEPWSGTSHTFDSSSSQHPISTQSITN
TDSEDSGERYLFPNPASAFPVSGGTSSSAPPRSTGNIHYAALDFQPSKPSIGSVTSGKKVDYVQVDLEKTQALQKTMHEQMCLRQSSEPP

--------------------------------------------------------------
>9355_9355_9_BCL2L13-GAB4_BCL2L13_chr22_18138598_ENST00000418951_GAB4_chr22_17446158_ENST00000400588_length(transcript)=1355nt_BP=121nt
ATGGCGTCCTCTTCTACTGTGCCTCTGGGATTTCACTATGAAACAAAGTATGTTGTTCTCAGCTACTTGGGACTCCTCTCTCAAGAGAAG
CTGCAAGAGCAACATCTTTCCTCACCCCAAGCCAACCCAACACCGCCCAACCTGAGAAACAACAGGGTCATCAATGAGCTCTCCTTCAAG
CCACCTGTCACAGAGCCCTGGTCTGGGACCAGCCACACCTTTGACTCCAGCTCCTCCCAACACCCCATCTCCACGCAGAGCATCACCAAC
ACAGACTCAGAAGACAGTGGAGAGAGGTATCTTTTCCCGAACCCGGCATCTGCATTTCCTGTTTCCGGTGGCACCAGCAGTTCAGCCCCG
CCGAGGAGCACTGGTAACATCCACTACGCGGCCCTGGACTTCCAGCCGAGCAAGCCATCCATAGGCTCTGTCACGTCCGGCAAGAAGGTG
GACTATGTCCAGGTGGATCTGGAGAAGACCCAGGCCCTGCAGAAGACCATGCATGAACAGATGTGCCTGCGGCAGTCCTCAGAGCCTCCC
AGGGGCGCCAAGCTGTGACTCGGGCCACCAAAACCAGAGTGGGGCCAGGACAGTGCCTCAGAGCTGCTCCGCCACACTCTAAAGCTCTGT
AATATCAGGGACCGCATCCCTTACATAGAGAGCAGAGGCCTGATCAATATACATCCTTTGCCTGCTTGGGGCCCACCTGTGCCTTTGGCT
GGCCATGGTCCCCACCTTCACCCCCTTGCTAGGAGCAGTTGCCAGCAAGCATCCTCAGTCTCTTCCTGCCCCTCAGACCCGGGCTCCCAA
CAGATTTCCACTCTCACACTTACTCATGGTCCTCAGCCTCTTCCTTCTAGCCTCTGGGCTGTTTCCCTCAATCCTGGAACATGAGGAGCT
ACCTTGCTGACCCGGGGACCCAAGGCCCACAGGCCACAGTGGACATGGACCTTTTCAGCCCTGGCATTTTTTGGTCAGGGGAGAGGCAAG
GCCATCAAACGTTGGAATAGTTGAGAAGGAAGGTTAAAGGTGGTCTTGAGAAGCAAAGGAATTAGATCCTTAGACCAGCAGGGCAGCTGA
TACCTGCAAGGGCTCCCACTTTCAGACTGAGGCCAGAGTATGGCAGCTGCTCCCGGGTGGGAGAGGCAGAGAGGGAAGGGCAAAAGGAAG
GGAAAACATGAAGACGAACAGCCGAAAGCCACAAGAAGCAGGGCTGGAGCTCCAGAGACTGGGGTGACAAGGACCAGGGTCAGGGCCCCA
GAAATCCGGAGCTGCAGGCTGGCTCTGCTGCTCTTTGCTGATGCCCCTTGGGGGGCCCTTGCCTGCCTAAGAAGGCTTGATCTGAGCTGG

>9355_9355_9_BCL2L13-GAB4_BCL2L13_chr22_18138598_ENST00000418951_GAB4_chr22_17446158_ENST00000400588_length(amino acids)=185AA_BP=40
MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQANPTPPNLRNNRVINELSFKPPVTEPWSGTSHTFDSSSSQHPISTQSITN
TDSEDSGERYLFPNPASAFPVSGGTSSSAPPRSTGNIHYAALDFQPSKPSIGSVTSGKKVDYVQVDLEKTQALQKTMHEQMCLRQSSEPP

--------------------------------------------------------------
>9355_9355_10_BCL2L13-GAB4_BCL2L13_chr22_18138598_ENST00000493680_GAB4_chr22_17446158_ENST00000400588_length(transcript)=1520nt_BP=286nt
GGCGGCGGTAGATTAGGGCCGCGGGTCGGAGCACTCACCGCCGCTGGGGGACCCTGTCGGAAGCAACTGCCGCCGCCGCCTCTTTCATCT
CTTCTGGGGCAGGGGCCAGGGCCAGGTTTTACACATCCATAAGTAGACCTTTTTGGAGCCTCACCAGCCAATTCAATGGCGTCCTCTTCT
ACTGTGCCTCTGGGATTTCACTATGAAACAAAGTATGTTGTTCTCAGCTACTTGGGACTCCTCTCTCAAGAGAAGCTGCAAGAGCAACAT
CTTTCCTCACCCCAAGCCAACCCAACACCGCCCAACCTGAGAAACAACAGGGTCATCAATGAGCTCTCCTTCAAGCCACCTGTCACAGAG
CCCTGGTCTGGGACCAGCCACACCTTTGACTCCAGCTCCTCCCAACACCCCATCTCCACGCAGAGCATCACCAACACAGACTCAGAAGAC
AGTGGAGAGAGGTATCTTTTCCCGAACCCGGCATCTGCATTTCCTGTTTCCGGTGGCACCAGCAGTTCAGCCCCGCCGAGGAGCACTGGT
AACATCCACTACGCGGCCCTGGACTTCCAGCCGAGCAAGCCATCCATAGGCTCTGTCACGTCCGGCAAGAAGGTGGACTATGTCCAGGTG
GATCTGGAGAAGACCCAGGCCCTGCAGAAGACCATGCATGAACAGATGTGCCTGCGGCAGTCCTCAGAGCCTCCCAGGGGCGCCAAGCTG
TGACTCGGGCCACCAAAACCAGAGTGGGGCCAGGACAGTGCCTCAGAGCTGCTCCGCCACACTCTAAAGCTCTGTAATATCAGGGACCGC
ATCCCTTACATAGAGAGCAGAGGCCTGATCAATATACATCCTTTGCCTGCTTGGGGCCCACCTGTGCCTTTGGCTGGCCATGGTCCCCAC
CTTCACCCCCTTGCTAGGAGCAGTTGCCAGCAAGCATCCTCAGTCTCTTCCTGCCCCTCAGACCCGGGCTCCCAACAGATTTCCACTCTC
ACACTTACTCATGGTCCTCAGCCTCTTCCTTCTAGCCTCTGGGCTGTTTCCCTCAATCCTGGAACATGAGGAGCTACCTTGCTGACCCGG
GGACCCAAGGCCCACAGGCCACAGTGGACATGGACCTTTTCAGCCCTGGCATTTTTTGGTCAGGGGAGAGGCAAGGCCATCAAACGTTGG
AATAGTTGAGAAGGAAGGTTAAAGGTGGTCTTGAGAAGCAAAGGAATTAGATCCTTAGACCAGCAGGGCAGCTGATACCTGCAAGGGCTC
CCACTTTCAGACTGAGGCCAGAGTATGGCAGCTGCTCCCGGGTGGGAGAGGCAGAGAGGGAAGGGCAAAAGGAAGGGAAAACATGAAGAC
GAACAGCCGAAAGCCACAAGAAGCAGGGCTGGAGCTCCAGAGACTGGGGTGACAAGGACCAGGGTCAGGGCCCCAGAAATCCGGAGCTGC

>9355_9355_10_BCL2L13-GAB4_BCL2L13_chr22_18138598_ENST00000493680_GAB4_chr22_17446158_ENST00000400588_length(amino acids)=185AA_BP=40
MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQANPTPPNLRNNRVINELSFKPPVTEPWSGTSHTFDSSSSQHPISTQSITN
TDSEDSGERYLFPNPASAFPVSGGTSSSAPPRSTGNIHYAALDFQPSKPSIGSVTSGKKVDYVQVDLEKTQALQKTMHEQMCLRQSSEPP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for BCL2L13-GAB4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BCL2L13-GAB4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BCL2L13-GAB4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource