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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ABCF1-PRR3 (FusionGDB2 ID:HG23TG80742)

Fusion Gene Summary for ABCF1-PRR3

check button Fusion gene summary
Fusion gene informationFusion gene name: ABCF1-PRR3
Fusion gene ID: hg23tg80742
HgeneTgene
Gene symbol

ABCF1

PRR3

Gene ID

23

80742

Gene nameATP binding cassette subfamily F member 1proline rich 3
SynonymsABC27|ABC50CAT56
Cytomap('ABCF1')('PRR3')

6p21.33

6p21.33

Type of geneprotein-codingprotein-coding
DescriptionATP-binding cassette sub-family F member 1ATP-binding cassette 50 (TNF-alpha stimulated)ATP-binding cassette, sub-family F (GCN20), member 1TNF-alpha-stimulated ABC proteinTNFalpha-inducible ATP-binding proteinproline-rich protein 3MHC class I region proline-rich protein CAT56proline-rich polypeptide 3
Modification date2020031320200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000326195, ENST00000376545, 
ENST00000396515, ENST00000383587, 
ENST00000383588, ENST00000400609, 
ENST00000412443, ENST00000416932, 
ENST00000419893, ENST00000420257, 
ENST00000421042, ENST00000421608, 
ENST00000423247, ENST00000426219, 
ENST00000448939, ENST00000452530, 
ENST00000454094, ENST00000456791, 
ENST00000457078, ENST00000457111, 
ENST00000457970, ENST00000470464, 
ENST00000475528, ENST00000485585, 
ENST00000486105, ENST00000494413, 
ENST00000495194, ENST00000546690, 
ENST00000552867, 
Fusion gene scores* DoF score6 X 5 X 4=1202 X 2 X 2=8
# samples 62
** MAII scorelog2(6/120*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(2/8*10)=1.32192809488736
Context

PubMed: ABCF1 [Title/Abstract] AND PRR3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointABCF1(30539337)-PRR3(30529611), # samples:2
Anticipated loss of major functional domain due to fusion event.ABCF1-PRR3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABCF1-PRR3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABCF1-PRR3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ABCF1-PRR3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ABCF1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across PRR3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PAADTCGA-IB-7652-01AABCF1chr6

30539337

-PRR3chr6

30529611

+
ChimerDB4PAADTCGA-IB-7652-01AABCF1chr6

30539337

+PRR3chr6

30529611

+


Top

Fusion Gene ORF analysis for ABCF1-PRR3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000326195ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-3UTRENST00000376545ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-3UTRENST00000396515ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000383592ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000418065ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000422140ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000422639ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000427729ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000432371ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000436805ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000442290ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000444972ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000449754ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000453232ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000454399ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000461523ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000469088ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000481092ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000484225ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000489106ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000326195ENST00000498679ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000383592ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000418065ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000422140ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000422639ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000427729ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000432371ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000436805ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000442290ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000444972ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000449754ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000453232ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000454399ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000461523ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000469088ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000481092ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000484225ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000489106ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000376545ENST00000498679ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000383592ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000418065ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000422140ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000422639ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000427729ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000432371ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000436805ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000442290ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000444972ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000449754ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000453232ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000454399ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000461523ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000469088ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000481092ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000484225ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000489106ABCF1chr6

30539337

+PRR3chr6

30529611

+
5CDS-intronENST00000396515ENST00000498679ABCF1chr6

30539337

+PRR3chr6

30529611

+
In-frameENST00000326195ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
In-frameENST00000326195ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
In-frameENST00000376545ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
In-frameENST00000376545ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
In-frameENST00000396515ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
In-frameENST00000396515ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000383587ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000383587ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000383588ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000383588ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000400609ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000400609ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000412443ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000412443ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000416932ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000416932ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000419893ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000419893ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000420257ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000420257ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000421042ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000421042ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000421608ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000421608ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000423247ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000423247ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000426219ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000426219ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000448939ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000448939ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000452530ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000452530ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000454094ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000454094ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000456791ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000456791ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000457078ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000457078ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000457111ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000457111ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000457970ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000457970ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000470464ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000470464ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000475528ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000475528ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000485585ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000485585ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000486105ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000486105ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000494413ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000494413ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000495194ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000495194ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000546690ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000546690ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000552867ENST00000376557ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3CDSENST00000552867ENST00000376560ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000383587ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000383588ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000400609ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000412443ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000416932ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000419893ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000420257ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000421042ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000421608ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000423247ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000426219ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000448939ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000452530ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000454094ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000456791ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000457078ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000457111ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000457970ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000470464ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000475528ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000485585ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000486105ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000494413ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000495194ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000546690ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-3UTRENST00000552867ENST00000498336ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000383587ENST00000383592ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000383587ENST00000418065ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000383587ENST00000422140ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000383587ENST00000422639ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000383587ENST00000427729ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000383587ENST00000432371ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000383587ENST00000436805ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000383587ENST00000442290ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000383587ENST00000444972ABCF1chr6

30539337

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30529611

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+PRR3chr6

30529611

+
intron-intronENST00000485585ENST00000498679ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000383592ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000418065ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000422140ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000422639ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000427729ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000432371ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000436805ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000442290ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000444972ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000449754ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000453232ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000454399ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000461523ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000469088ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000481092ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000484225ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000489106ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000486105ENST00000498679ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000383592ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000418065ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000422140ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000422639ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000427729ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000432371ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000436805ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000442290ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000444972ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000449754ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000453232ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000454399ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000461523ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000469088ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000481092ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000484225ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000489106ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000494413ENST00000498679ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000383592ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000418065ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000422140ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000422639ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000427729ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000432371ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000436805ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000442290ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000444972ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000449754ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000453232ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000454399ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000461523ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000469088ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000481092ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000484225ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000489106ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000495194ENST00000498679ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000383592ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000418065ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000422140ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000422639ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000427729ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000432371ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000436805ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000442290ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000444972ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000449754ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000453232ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000454399ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000461523ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000469088ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000481092ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000484225ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000489106ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000546690ENST00000498679ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000383592ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000418065ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000422140ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000422639ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000427729ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000432371ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000436805ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000442290ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000444972ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000449754ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000453232ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000454399ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000461523ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000469088ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000481092ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000484225ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000489106ABCF1chr6

30539337

+PRR3chr6

30529611

+
intron-intronENST00000552867ENST00000498679ABCF1chr6

30539337

+PRR3chr6

30529611

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

Top

Fusion Genomic Features for ABCF1-PRR3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ABCF1chr630539337+PRR3chr630529610+1.04E-101
ABCF1chr630539337+PRR3chr630529610+1.04E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for ABCF1-PRR3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:30539337/chr6:30529611)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePRR3chr6:30539337chr6:30529611ENST000003835920412_1180189.0Compositional biasNote=Pro-rich
TgenePRR3chr6:30539337chr6:30529611ENST000004180650312_1180168.0Compositional biasNote=Pro-rich
TgenePRR3chr6:30539337chr6:30529611ENST000004221400312_1180168.0Compositional biasNote=Pro-rich
TgenePRR3chr6:30539337chr6:30529611ENST000004226390312_1180168.0Compositional biasNote=Pro-rich
TgenePRR3chr6:30539337chr6:30529611ENST000004277290412_1180189.0Compositional biasNote=Pro-rich
TgenePRR3chr6:30539337chr6:30529611ENST000004323710412_1180189.0Compositional biasNote=Pro-rich
TgenePRR3chr6:30539337chr6:30529611ENST000004368050312_1180168.0Compositional biasNote=Pro-rich
TgenePRR3chr6:30539337chr6:30529611ENST000004422900312_1180168.0Compositional biasNote=Pro-rich
TgenePRR3chr6:30539337chr6:30529611ENST000004449720312_1180168.0Compositional biasNote=Pro-rich
TgenePRR3chr6:30539337chr6:30529611ENST000004497540412_1180189.0Compositional biasNote=Pro-rich
TgenePRR3chr6:30539337chr6:30529611ENST000004532320412_1180189.0Compositional biasNote=Pro-rich
TgenePRR3chr6:30539337chr6:30529611ENST000004543990412_1180189.0Compositional biasNote=Pro-rich
TgenePRR3chr6:30539337chr6:30529611ENST0000037655703155_18335168.0Zinc fingerC3H1-type
TgenePRR3chr6:30539337chr6:30529611ENST0000037656014155_18356189.0Zinc fingerC3H1-type
TgenePRR3chr6:30539337chr6:30529611ENST0000038359204155_1830189.0Zinc fingerC3H1-type
TgenePRR3chr6:30539337chr6:30529611ENST0000041806503155_1830168.0Zinc fingerC3H1-type
TgenePRR3chr6:30539337chr6:30529611ENST0000042214003155_1830168.0Zinc fingerC3H1-type
TgenePRR3chr6:30539337chr6:30529611ENST0000042263903155_1830168.0Zinc fingerC3H1-type
TgenePRR3chr6:30539337chr6:30529611ENST0000042772904155_1830189.0Zinc fingerC3H1-type
TgenePRR3chr6:30539337chr6:30529611ENST0000043237104155_1830189.0Zinc fingerC3H1-type
TgenePRR3chr6:30539337chr6:30529611ENST0000043680503155_1830168.0Zinc fingerC3H1-type
TgenePRR3chr6:30539337chr6:30529611ENST0000044229003155_1830168.0Zinc fingerC3H1-type
TgenePRR3chr6:30539337chr6:30529611ENST0000044497203155_1830168.0Zinc fingerC3H1-type
TgenePRR3chr6:30539337chr6:30529611ENST0000044975404155_1830189.0Zinc fingerC3H1-type
TgenePRR3chr6:30539337chr6:30529611ENST0000045323204155_1830189.0Zinc fingerC3H1-type
TgenePRR3chr6:30539337chr6:30529611ENST0000045439904155_1830189.0Zinc fingerC3H1-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABCF1chr6:30539337chr6:30529611ENST00000326195+125141_24324846.0Compositional biasNote=Glu-rich
HgeneABCF1chr6:30539337chr6:30529611ENST00000376545+124141_24324808.0Compositional biasNote=Glu-rich
HgeneABCF1chr6:30539337chr6:30529611ENST00000383587+124141_2430808.0Compositional biasNote=Glu-rich
HgeneABCF1chr6:30539337chr6:30529611ENST00000383588+125141_2430846.0Compositional biasNote=Glu-rich
HgeneABCF1chr6:30539337chr6:30529611ENST00000412443+124141_2430808.0Compositional biasNote=Glu-rich
HgeneABCF1chr6:30539337chr6:30529611ENST00000419893+125141_2430846.0Compositional biasNote=Glu-rich
HgeneABCF1chr6:30539337chr6:30529611ENST00000420257+124141_2430808.0Compositional biasNote=Glu-rich
HgeneABCF1chr6:30539337chr6:30529611ENST00000421042+124141_2430808.0Compositional biasNote=Glu-rich
HgeneABCF1chr6:30539337chr6:30529611ENST00000423247+125141_2430846.0Compositional biasNote=Glu-rich
HgeneABCF1chr6:30539337chr6:30529611ENST00000426219+125141_2430846.0Compositional biasNote=Glu-rich
HgeneABCF1chr6:30539337chr6:30529611ENST00000448939+124141_2430808.0Compositional biasNote=Glu-rich
HgeneABCF1chr6:30539337chr6:30529611ENST00000452530+124141_2430808.0Compositional biasNote=Glu-rich
HgeneABCF1chr6:30539337chr6:30529611ENST00000457078+125141_2430846.0Compositional biasNote=Glu-rich
HgeneABCF1chr6:30539337chr6:30529611ENST00000457111+125141_2430846.0Compositional biasNote=Glu-rich
HgeneABCF1chr6:30539337chr6:30529611ENST00000326195+125304_54824846.0DomainABC transporter 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000326195+125625_84024846.0DomainABC transporter 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000376545+124304_54824808.0DomainABC transporter 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000376545+124625_84024808.0DomainABC transporter 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000383587+124304_5480808.0DomainABC transporter 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000383587+124625_8400808.0DomainABC transporter 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000383588+125304_5480846.0DomainABC transporter 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000383588+125625_8400846.0DomainABC transporter 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000412443+124304_5480808.0DomainABC transporter 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000412443+124625_8400808.0DomainABC transporter 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000419893+125304_5480846.0DomainABC transporter 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000419893+125625_8400846.0DomainABC transporter 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000420257+124304_5480808.0DomainABC transporter 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000420257+124625_8400808.0DomainABC transporter 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000421042+124304_5480808.0DomainABC transporter 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000421042+124625_8400808.0DomainABC transporter 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000423247+125304_5480846.0DomainABC transporter 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000423247+125625_8400846.0DomainABC transporter 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000426219+125304_5480846.0DomainABC transporter 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000426219+125625_8400846.0DomainABC transporter 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000448939+124304_5480808.0DomainABC transporter 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000448939+124625_8400808.0DomainABC transporter 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000452530+124304_5480808.0DomainABC transporter 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000452530+124625_8400808.0DomainABC transporter 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000457078+125304_5480846.0DomainABC transporter 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000457078+125625_8400846.0DomainABC transporter 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000457111+125304_5480846.0DomainABC transporter 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000457111+125625_8400846.0DomainABC transporter 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000326195+125336_34324846.0Nucleotide bindingATP 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000326195+125658_66524846.0Nucleotide bindingATP 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000376545+124336_34324808.0Nucleotide bindingATP 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000376545+124658_66524808.0Nucleotide bindingATP 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000383587+124336_3430808.0Nucleotide bindingATP 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000383587+124658_6650808.0Nucleotide bindingATP 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000383588+125336_3430846.0Nucleotide bindingATP 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000383588+125658_6650846.0Nucleotide bindingATP 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000412443+124336_3430808.0Nucleotide bindingATP 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000412443+124658_6650808.0Nucleotide bindingATP 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000419893+125336_3430846.0Nucleotide bindingATP 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000419893+125658_6650846.0Nucleotide bindingATP 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000420257+124336_3430808.0Nucleotide bindingATP 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000420257+124658_6650808.0Nucleotide bindingATP 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000421042+124336_3430808.0Nucleotide bindingATP 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000421042+124658_6650808.0Nucleotide bindingATP 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000423247+125336_3430846.0Nucleotide bindingATP 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000423247+125658_6650846.0Nucleotide bindingATP 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000426219+125336_3430846.0Nucleotide bindingATP 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000426219+125658_6650846.0Nucleotide bindingATP 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000448939+124336_3430808.0Nucleotide bindingATP 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000448939+124658_6650808.0Nucleotide bindingATP 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000452530+124336_3430808.0Nucleotide bindingATP 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000452530+124658_6650808.0Nucleotide bindingATP 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000457078+125336_3430846.0Nucleotide bindingATP 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000457078+125658_6650846.0Nucleotide bindingATP 2
HgeneABCF1chr6:30539337chr6:30529611ENST00000457111+125336_3430846.0Nucleotide bindingATP 1
HgeneABCF1chr6:30539337chr6:30529611ENST00000457111+125658_6650846.0Nucleotide bindingATP 2
TgenePRR3chr6:30539337chr6:30529611ENST000003765570312_11835168.0Compositional biasNote=Pro-rich
TgenePRR3chr6:30539337chr6:30529611ENST000003765601412_11856189.0Compositional biasNote=Pro-rich


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Fusion Gene Sequence for ABCF1-PRR3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for ABCF1-PRR3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ABCF1-PRR3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ABCF1-PRR3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneABCF1C0020517Hypersensitivity1CTD_human
HgeneABCF1C0032285Pneumonia1CTD_human
HgeneABCF1C0032300Lobar Pneumonia1CTD_human
HgeneABCF1C0235874Disease Exacerbation1CTD_human
HgeneABCF1C0887898Experimental Lung Inflammation1CTD_human
HgeneABCF1C1527304Allergic Reaction1CTD_human
HgeneABCF1C3714636Pneumonitis1CTD_human