Fusion Gene Studies
in Kim Lab

FusionBase FusionGDB FusionGDB2 FusionPDB FusionNeoAntigen FusionAI FusionNW FGviewer Publication Contact
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:ATXN10-FBLN1 (FusionGDB2 ID:HG25814TG2192)

Fusion Gene Summary for ATXN10-FBLN1

check button Fusion gene summary
Fusion gene informationFusion gene name: ATXN10-FBLN1
Fusion gene ID: hg25814tg2192
HgeneTgene
Gene symbol

ATXN10

FBLN1

Gene ID

25814

2192

Gene nameataxin 10fibulin 1
SynonymsE46L|HUMEEP|SCA10FBLN|FIBL1
Cytomap('ATXN10')('FBLN1')

22q13.31

22q13.31

Type of geneprotein-codingprotein-coding
Descriptionataxin-10brain protein E46 homologspinocerebellar ataxia type 10 proteinfibulin-1
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000498009, ENST00000252934, 
ENST00000381061, ENST00000402380, 
ENST00000402380, ENST00000498009, 
ENST00000252934, ENST00000381061, 
Fusion gene scores* DoF score16 X 12 X 11=211222 X 22 X 9=4356
# samples 1927
** MAII scorelog2(19/2112*10)=-3.47453851102751
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(27/4356*10)=-4.01197264166608
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ATXN10 [Title/Abstract] AND FBLN1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointATXN10(46088958)-FBLN1(45996187), # samples:2
Anticipated loss of major functional domain due to fusion event.ATXN10-FBLN1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ATXN10-FBLN1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ATXN10-FBLN1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ATXN10-FBLN1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ATXN10-FBLN1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ATXN10-FBLN1 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
FBLN1-ATXN10 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
FBLN1-ATXN10 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneATXN10

GO:0031175

neuron projection development

16498633

TgeneFBLN1

GO:0001933

negative regulation of protein phosphorylation

11792823

TgeneFBLN1

GO:0007162

negative regulation of cell adhesion

11792823

TgeneFBLN1

GO:0007229

integrin-mediated signaling pathway

11792823

TgeneFBLN1

GO:0070373

negative regulation of ERK1 and ERK2 cascade

11792823

TgeneFBLN1

GO:0072378

blood coagulation, fibrin clot formation

7642629

TgeneFBLN1

GO:1900025

negative regulation of substrate adhesion-dependent cell spreading

11792823

TgeneFBLN1

GO:2000146

negative regulation of cell motility

11792823

TgeneFBLN1

GO:2000647

negative regulation of stem cell proliferation

11238726


check buttonFusion gene breakpoints across ATXN10 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across FBLN1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-13-0795-01AATXN10chr22

46085783

+FBLN1chr22

45996187

+
ChimerDB4OVTCGA-13-0795-01AATXN10chr22

46088958

-FBLN1chr22

45996187

+
ChimerDB4OVTCGA-13-0795-01AATXN10chr22

46088958

+FBLN1chr22

45996187

+
ChimerDB4UCECTCGA-AX-A1CC-01AATXN10chr22

46088958

+FBLN1chr22

45914562

+


Top

Fusion Gene ORF analysis for ATXN10-FBLN1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000498009ENST00000262722ATXN10chr22

46088958

+FBLN1chr22

45914562

+
3UTR-3CDSENST00000498009ENST00000327858ATXN10chr22

46088958

+FBLN1chr22

45914562

+
3UTR-3CDSENST00000498009ENST00000340923ATXN10chr22

46088958

+FBLN1chr22

45914562

+
3UTR-3CDSENST00000498009ENST00000348697ATXN10chr22

46085783

+FBLN1chr22

45996187

+
3UTR-3CDSENST00000498009ENST00000348697ATXN10chr22

46088958

+FBLN1chr22

45996187

+
3UTR-3CDSENST00000498009ENST00000348697ATXN10chr22

46088958

+FBLN1chr22

45914562

+
3UTR-3CDSENST00000498009ENST00000402984ATXN10chr22

46088958

+FBLN1chr22

45914562

+
3UTR-3CDSENST00000498009ENST00000442170ATXN10chr22

46088958

+FBLN1chr22

45914562

+
3UTR-intronENST00000498009ENST00000262722ATXN10chr22

46085783

+FBLN1chr22

45996187

+
3UTR-intronENST00000498009ENST00000262722ATXN10chr22

46088958

+FBLN1chr22

45996187

+
3UTR-intronENST00000498009ENST00000327858ATXN10chr22

46085783

+FBLN1chr22

45996187

+
3UTR-intronENST00000498009ENST00000327858ATXN10chr22

46088958

+FBLN1chr22

45996187

+
3UTR-intronENST00000498009ENST00000340923ATXN10chr22

46085783

+FBLN1chr22

45996187

+
3UTR-intronENST00000498009ENST00000340923ATXN10chr22

46088958

+FBLN1chr22

45996187

+
3UTR-intronENST00000498009ENST00000402984ATXN10chr22

46085783

+FBLN1chr22

45996187

+
3UTR-intronENST00000498009ENST00000402984ATXN10chr22

46088958

+FBLN1chr22

45996187

+
3UTR-intronENST00000498009ENST00000442170ATXN10chr22

46085783

+FBLN1chr22

45996187

+
3UTR-intronENST00000498009ENST00000442170ATXN10chr22

46088958

+FBLN1chr22

45996187

+
3UTR-intronENST00000498009ENST00000476366ATXN10chr22

46085783

+FBLN1chr22

45996187

+
3UTR-intronENST00000498009ENST00000476366ATXN10chr22

46088958

+FBLN1chr22

45996187

+
3UTR-intronENST00000498009ENST00000476366ATXN10chr22

46088958

+FBLN1chr22

45914562

+
5CDS-intronENST00000252934ENST00000262722ATXN10chr22

46085783

+FBLN1chr22

45996187

+
5CDS-intronENST00000252934ENST00000262722ATXN10chr22

46088958

+FBLN1chr22

45996187

+
5CDS-intronENST00000252934ENST00000327858ATXN10chr22

46085783

+FBLN1chr22

45996187

+
5CDS-intronENST00000252934ENST00000327858ATXN10chr22

46088958

+FBLN1chr22

45996187

+
5CDS-intronENST00000252934ENST00000340923ATXN10chr22

46085783

+FBLN1chr22

45996187

+
5CDS-intronENST00000252934ENST00000340923ATXN10chr22

46088958

+FBLN1chr22

45996187

+
5CDS-intronENST00000252934ENST00000402984ATXN10chr22

46085783

+FBLN1chr22

45996187

+
5CDS-intronENST00000252934ENST00000402984ATXN10chr22

46088958

+FBLN1chr22

45996187

+
5CDS-intronENST00000252934ENST00000442170ATXN10chr22

46085783

+FBLN1chr22

45996187

+
5CDS-intronENST00000252934ENST00000442170ATXN10chr22

46088958

+FBLN1chr22

45996187

+
5CDS-intronENST00000252934ENST00000476366ATXN10chr22

46085783

+FBLN1chr22

45996187

+
5CDS-intronENST00000252934ENST00000476366ATXN10chr22

46088958

+FBLN1chr22

45996187

+
5CDS-intronENST00000252934ENST00000476366ATXN10chr22

46088958

+FBLN1chr22

45914562

+
5CDS-intronENST00000381061ENST00000262722ATXN10chr22

46088958

+FBLN1chr22

45996187

+
5CDS-intronENST00000381061ENST00000327858ATXN10chr22

46088958

+FBLN1chr22

45996187

+
5CDS-intronENST00000381061ENST00000340923ATXN10chr22

46088958

+FBLN1chr22

45996187

+
5CDS-intronENST00000381061ENST00000402984ATXN10chr22

46088958

+FBLN1chr22

45996187

+
5CDS-intronENST00000381061ENST00000442170ATXN10chr22

46088958

+FBLN1chr22

45996187

+
5CDS-intronENST00000381061ENST00000476366ATXN10chr22

46088958

+FBLN1chr22

45996187

+
5CDS-intronENST00000381061ENST00000476366ATXN10chr22

46088958

+FBLN1chr22

45914562

+
Frame-shiftENST00000252934ENST00000348697ATXN10chr22

46088958

+FBLN1chr22

45996187

+
Frame-shiftENST00000381061ENST00000348697ATXN10chr22

46088958

+FBLN1chr22

45996187

+
In-frameENST00000252934ENST00000262722ATXN10chr22

46088958

+FBLN1chr22

45914562

+
In-frameENST00000252934ENST00000327858ATXN10chr22

46088958

+FBLN1chr22

45914562

+
In-frameENST00000252934ENST00000340923ATXN10chr22

46088958

+FBLN1chr22

45914562

+
In-frameENST00000252934ENST00000348697ATXN10chr22

46085783

+FBLN1chr22

45996187

+
In-frameENST00000252934ENST00000348697ATXN10chr22

46088958

+FBLN1chr22

45914562

+
In-frameENST00000252934ENST00000402984ATXN10chr22

46088958

+FBLN1chr22

45914562

+
In-frameENST00000252934ENST00000442170ATXN10chr22

46088958

+FBLN1chr22

45914562

+
In-frameENST00000381061ENST00000262722ATXN10chr22

46088958

+FBLN1chr22

45914562

+
In-frameENST00000381061ENST00000327858ATXN10chr22

46088958

+FBLN1chr22

45914562

+
In-frameENST00000381061ENST00000340923ATXN10chr22

46088958

+FBLN1chr22

45914562

+
In-frameENST00000381061ENST00000348697ATXN10chr22

46088958

+FBLN1chr22

45914562

+
In-frameENST00000381061ENST00000402984ATXN10chr22

46088958

+FBLN1chr22

45914562

+
In-frameENST00000381061ENST00000442170ATXN10chr22

46088958

+FBLN1chr22

45914562

+
intron-3CDSENST00000381061ENST00000348697ATXN10chr22

46085783

+FBLN1chr22

45996187

+
intron-3CDSENST00000402380ENST00000262722ATXN10chr22

46088958

+FBLN1chr22

45914562

+
intron-3CDSENST00000402380ENST00000327858ATXN10chr22

46088958

+FBLN1chr22

45914562

+
intron-3CDSENST00000402380ENST00000340923ATXN10chr22

46088958

+FBLN1chr22

45914562

+
intron-3CDSENST00000402380ENST00000348697ATXN10chr22

46085783

+FBLN1chr22

45996187

+
intron-3CDSENST00000402380ENST00000348697ATXN10chr22

46088958

+FBLN1chr22

45996187

+
intron-3CDSENST00000402380ENST00000348697ATXN10chr22

46088958

+FBLN1chr22

45914562

+
intron-3CDSENST00000402380ENST00000402984ATXN10chr22

46088958

+FBLN1chr22

45914562

+
intron-3CDSENST00000402380ENST00000442170ATXN10chr22

46088958

+FBLN1chr22

45914562

+
intron-intronENST00000381061ENST00000262722ATXN10chr22

46085783

+FBLN1chr22

45996187

+
intron-intronENST00000381061ENST00000327858ATXN10chr22

46085783

+FBLN1chr22

45996187

+
intron-intronENST00000381061ENST00000340923ATXN10chr22

46085783

+FBLN1chr22

45996187

+
intron-intronENST00000381061ENST00000402984ATXN10chr22

46085783

+FBLN1chr22

45996187

+
intron-intronENST00000381061ENST00000442170ATXN10chr22

46085783

+FBLN1chr22

45996187

+
intron-intronENST00000381061ENST00000476366ATXN10chr22

46085783

+FBLN1chr22

45996187

+
intron-intronENST00000402380ENST00000262722ATXN10chr22

46085783

+FBLN1chr22

45996187

+
intron-intronENST00000402380ENST00000262722ATXN10chr22

46088958

+FBLN1chr22

45996187

+
intron-intronENST00000402380ENST00000327858ATXN10chr22

46085783

+FBLN1chr22

45996187

+
intron-intronENST00000402380ENST00000327858ATXN10chr22

46088958

+FBLN1chr22

45996187

+
intron-intronENST00000402380ENST00000340923ATXN10chr22

46085783

+FBLN1chr22

45996187

+
intron-intronENST00000402380ENST00000340923ATXN10chr22

46088958

+FBLN1chr22

45996187

+
intron-intronENST00000402380ENST00000402984ATXN10chr22

46085783

+FBLN1chr22

45996187

+
intron-intronENST00000402380ENST00000402984ATXN10chr22

46088958

+FBLN1chr22

45996187

+
intron-intronENST00000402380ENST00000442170ATXN10chr22

46085783

+FBLN1chr22

45996187

+
intron-intronENST00000402380ENST00000442170ATXN10chr22

46088958

+FBLN1chr22

45996187

+
intron-intronENST00000402380ENST00000476366ATXN10chr22

46085783

+FBLN1chr22

45996187

+
intron-intronENST00000402380ENST00000476366ATXN10chr22

46088958

+FBLN1chr22

45996187

+
intron-intronENST00000402380ENST00000476366ATXN10chr22

46088958

+FBLN1chr22

45914562

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000381061ATXN10chr2246088958+ENST00000348697FBLN1chr2245914562+31864652662497743
ENST00000381061ATXN10chr2246088958+ENST00000402984FBLN1chr2245914562+26384652662551761
ENST00000381061ATXN10chr2246088958+ENST00000262722FBLN1chr2245914562+25344652662437723
ENST00000381061ATXN10chr2246088958+ENST00000327858FBLN1chr2245914562+31874652662497743
ENST00000381061ATXN10chr2246088958+ENST00000442170FBLN1chr2245914562+29014652662191641
ENST00000381061ATXN10chr2246088958+ENST00000340923FBLN1chr2245914562+27244652662086606
ENST00000252934ATXN10chr2246088958+ENST00000348697FBLN1chr2245914562+33776562652688807
ENST00000252934ATXN10chr2246088958+ENST00000402984FBLN1chr2245914562+28296562652742825
ENST00000252934ATXN10chr2246088958+ENST00000262722FBLN1chr2245914562+27256562652628787
ENST00000252934ATXN10chr2246088958+ENST00000327858FBLN1chr2245914562+33786562652688807
ENST00000252934ATXN10chr2246088958+ENST00000442170FBLN1chr2245914562+30926562652382705
ENST00000252934ATXN10chr2246088958+ENST00000340923FBLN1chr2245914562+29156562652277670

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000381061ENST00000348697ATXN10chr2246088958+FBLN1chr2245914562+0.0087511150.99124885
ENST00000381061ENST00000402984ATXN10chr2246088958+FBLN1chr2245914562+0.0129890940.98701096
ENST00000381061ENST00000262722ATXN10chr2246088958+FBLN1chr2245914562+0.0161543660.9838456
ENST00000381061ENST00000327858ATXN10chr2246088958+FBLN1chr2245914562+0.0090391130.9909609
ENST00000381061ENST00000442170ATXN10chr2246088958+FBLN1chr2245914562+0.0189763940.98102355
ENST00000381061ENST00000340923ATXN10chr2246088958+FBLN1chr2245914562+0.0186338570.98136616
ENST00000252934ENST00000348697ATXN10chr2246088958+FBLN1chr2245914562+0.0070492510.9929508
ENST00000252934ENST00000402984ATXN10chr2246088958+FBLN1chr2245914562+0.0078848540.9921151
ENST00000252934ENST00000262722ATXN10chr2246088958+FBLN1chr2245914562+0.0124144820.98758554
ENST00000252934ENST00000327858ATXN10chr2246088958+FBLN1chr2245914562+0.007330780.9926692
ENST00000252934ENST00000442170ATXN10chr2246088958+FBLN1chr2245914562+0.0161621220.98383784
ENST00000252934ENST00000340923ATXN10chr2246088958+FBLN1chr2245914562+0.0172118150.98278815

Top

Fusion Genomic Features for ATXN10-FBLN1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ATXN10chr2246085783+FBLN1chr2245996186+0.12521020.87478983
ATXN10chr2246088958+FBLN1chr2245996186+0.0019036210.9980964
ATXN10chr2246088958+FBLN1chr2245914561+4.72E-060.99999523
ATXN10chr2246085783+FBLN1chr2245996186+0.12521020.87478983
ATXN10chr2246088958+FBLN1chr2245996186+0.0019036210.9980964
ATXN10chr2246088958+FBLN1chr2245914561+4.72E-060.99999523

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for ATXN10-FBLN1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:46088958/chr22:45996187)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneFBLN1chr22:46085783chr22:45996187ENST00000262722015112_1440684.0DomainAnaphylatoxin-like 3
TgeneFBLN1chr22:46085783chr22:45996187ENST00000262722015176_2150684.0DomainEGF-like 1
TgeneFBLN1chr22:46085783chr22:45996187ENST00000262722015216_2610684.0DomainEGF-like 2%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST00000262722015262_3070684.0DomainEGF-like 3%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST00000262722015308_3550684.0DomainEGF-like 4%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST00000262722015356_3980684.0DomainEGF-like 5%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST0000026272201536_760684.0DomainAnaphylatoxin-like 1
TgeneFBLN1chr22:46085783chr22:45996187ENST00000262722015399_4400684.0DomainEGF-like 6%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST00000262722015441_4800684.0DomainEGF-like 7%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST00000262722015481_5240684.0DomainEGF-like 8%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST00000262722015525_5780684.0DomainEGF-like 9%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST0000026272201577_1110684.0DomainAnaphylatoxin-like 2
TgeneFBLN1chr22:46085783chr22:45996187ENST00000340923015112_1440567.0DomainAnaphylatoxin-like 3
TgeneFBLN1chr22:46085783chr22:45996187ENST00000340923015176_2150567.0DomainEGF-like 1
TgeneFBLN1chr22:46085783chr22:45996187ENST00000340923015216_2610567.0DomainEGF-like 2%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST00000340923015262_3070567.0DomainEGF-like 3%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST00000340923015308_3550567.0DomainEGF-like 4%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST00000340923015356_3980567.0DomainEGF-like 5%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST0000034092301536_760567.0DomainAnaphylatoxin-like 1
TgeneFBLN1chr22:46085783chr22:45996187ENST00000340923015399_4400567.0DomainEGF-like 6%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST00000340923015441_4800567.0DomainEGF-like 7%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST00000340923015481_5240567.0DomainEGF-like 8%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST00000340923015525_5780567.0DomainEGF-like 9%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST0000034092301577_1110567.0DomainAnaphylatoxin-like 2
TgeneFBLN1chr22:46088958chr22:45914562ENST00000262722015112_14426684.0DomainAnaphylatoxin-like 3
TgeneFBLN1chr22:46088958chr22:45914562ENST00000262722015176_21526684.0DomainEGF-like 1
TgeneFBLN1chr22:46088958chr22:45914562ENST00000262722015216_26126684.0DomainEGF-like 2%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000262722015262_30726684.0DomainEGF-like 3%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000262722015308_35526684.0DomainEGF-like 4%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000262722015356_39826684.0DomainEGF-like 5%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST0000026272201536_7626684.0DomainAnaphylatoxin-like 1
TgeneFBLN1chr22:46088958chr22:45914562ENST00000262722015399_44026684.0DomainEGF-like 6%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000262722015441_48026684.0DomainEGF-like 7%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000262722015481_52426684.0DomainEGF-like 8%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000262722015525_57826684.0DomainEGF-like 9%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST0000026272201577_11126684.0DomainAnaphylatoxin-like 2
TgeneFBLN1chr22:46088958chr22:45914562ENST00000327858017112_14426704.0DomainAnaphylatoxin-like 3
TgeneFBLN1chr22:46088958chr22:45914562ENST00000327858017176_21526704.0DomainEGF-like 1
TgeneFBLN1chr22:46088958chr22:45914562ENST00000327858017216_26126704.0DomainEGF-like 2%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000327858017262_30726704.0DomainEGF-like 3%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000327858017308_35526704.0DomainEGF-like 4%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000327858017356_39826704.0DomainEGF-like 5%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST0000032785801736_7626704.0DomainAnaphylatoxin-like 1
TgeneFBLN1chr22:46088958chr22:45914562ENST00000327858017399_44026704.0DomainEGF-like 6%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000327858017441_48026704.0DomainEGF-like 7%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000327858017481_52426704.0DomainEGF-like 8%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000327858017525_57826704.0DomainEGF-like 9%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST0000032785801777_11126704.0DomainAnaphylatoxin-like 2
TgeneFBLN1chr22:46088958chr22:45914562ENST00000340923015112_14426567.0DomainAnaphylatoxin-like 3
TgeneFBLN1chr22:46088958chr22:45914562ENST00000340923015176_21526567.0DomainEGF-like 1
TgeneFBLN1chr22:46088958chr22:45914562ENST00000340923015216_26126567.0DomainEGF-like 2%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000340923015262_30726567.0DomainEGF-like 3%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000340923015308_35526567.0DomainEGF-like 4%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000340923015356_39826567.0DomainEGF-like 5%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST0000034092301536_7626567.0DomainAnaphylatoxin-like 1
TgeneFBLN1chr22:46088958chr22:45914562ENST00000340923015399_44026567.0DomainEGF-like 6%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000340923015441_48026567.0DomainEGF-like 7%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000340923015481_52426567.0DomainEGF-like 8%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000340923015525_57826567.0DomainEGF-like 9%3B calcium-binding
TgeneFBLN1chr22:46088958chr22:45914562ENST0000034092301577_11126567.0DomainAnaphylatoxin-like 2
TgeneFBLN1chr22:46085783chr22:45996187ENST00000262722015356_4400684.0RegionNote=Self-association and FN1-binding%3B calcium is necessary for homotypic binding%2C but not for heterotypic binding
TgeneFBLN1chr22:46085783chr22:45996187ENST00000340923015356_4400567.0RegionNote=Self-association and FN1-binding%3B calcium is necessary for homotypic binding%2C but not for heterotypic binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000262722015356_44026684.0RegionNote=Self-association and FN1-binding%3B calcium is necessary for homotypic binding%2C but not for heterotypic binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000327858017356_44026704.0RegionNote=Self-association and FN1-binding%3B calcium is necessary for homotypic binding%2C but not for heterotypic binding
TgeneFBLN1chr22:46088958chr22:45914562ENST00000340923015356_44026567.0RegionNote=Self-association and FN1-binding%3B calcium is necessary for homotypic binding%2C but not for heterotypic binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneFBLN1chr22:46085783chr22:45996187ENST000003278581517112_144657704.0DomainAnaphylatoxin-like 3
TgeneFBLN1chr22:46085783chr22:45996187ENST000003278581517176_215657704.0DomainEGF-like 1
TgeneFBLN1chr22:46085783chr22:45996187ENST000003278581517216_261657704.0DomainEGF-like 2%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST000003278581517262_307657704.0DomainEGF-like 3%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST000003278581517308_355657704.0DomainEGF-like 4%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST000003278581517356_398657704.0DomainEGF-like 5%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST00000327858151736_76657704.0DomainAnaphylatoxin-like 1
TgeneFBLN1chr22:46085783chr22:45996187ENST000003278581517399_440657704.0DomainEGF-like 6%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST000003278581517441_480657704.0DomainEGF-like 7%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST000003278581517481_524657704.0DomainEGF-like 8%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST000003278581517525_578657704.0DomainEGF-like 9%3B calcium-binding
TgeneFBLN1chr22:46085783chr22:45996187ENST00000327858151777_111657704.0DomainAnaphylatoxin-like 2
TgeneFBLN1chr22:46085783chr22:45996187ENST000003278581517356_440657704.0RegionNote=Self-association and FN1-binding%3B calcium is necessary for homotypic binding%2C but not for heterotypic binding


Top

Fusion Gene Sequence for ATXN10-FBLN1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>8370_8370_1_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000252934_FBLN1_chr22_45914562_ENST00000262722_length(transcript)=2725nt_BP=656nt
GGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGGC
GGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATCC
TACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGGC
GGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGCT
CTTCAAAGAGCAGCGGAACCGAGAAACAGCACCCAGGACTATCTTCCAAAGAGTTCTGGATATCCTAAAGAAATCTTCTCATGCTGTTGA
GCTTGCCTGCAGAGATCCATCCCAAGTGGAAAACCTGGCTTCCAGTCTGCAGTTAATAACAGAATGCTTCAGGTGTCTTCGCAATGCTTG
CATAGAGTGTTCTGTGAACCAGAATTCAATCAGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCG
AGTGGAACAGGAATCTCTGTTGACAGTGGACGCGGATGTCCTCCTGGAGGCCTGCTGTGCGGACGGACACCGGATGGCCACTCATCAGAA
GGACTGCTCGCTGCCATATGCTACGGAATCCAAAGAATGCAGGATGGTGCAGGAGCAGTGCTGCCACAGCCAGCTGGAGGAGCTGCACTG
TGCCACGGGCATCAGCCTGGCCAACGAGCAGGACCGCTGTGCCACGCCCCACGGTGACAACGCCAGCCTGGAGGCCACATTTGTGAAGAG
GTGCTGCCATTGCTGTCTGCTGGGGAGGGCGGCCCAGGCCCAGGGCCAGAGCTGCGAGTACAGCCTCATGGTTGGCTACCAGTGTGGACA
GGTCTTCCAGGCATGCTGTGTCAAGAGCCAGGAGACCGGAGATTTGGATGTCGGGGGCCTCCAAGAAACGGATAAGATCATTGAGGTTGA
GGAGGAACAAGAGGACCCATATCTGAATGACCGCTGCCGAGGAGGCGGGCCCTGCAAGCAGCAGTGCCGAGACACGGGTGACGAGGTGGT
CTGCTCCTGCTTCGTGGGCTACCAGCTGCTGTCTGATGGTGTCTCCTGTGAAGATGTCAATGAATGCATCACGGGCAGCCACAGCTGCCG
GCTTGGAGAATCCTGCATCAACACAGTGGGCTCTTTCCGCTGCCAGCGGGACAGCAGCTGCGGGACTGGCTATGAGCTCACAGAGGACAA
TAGCTGCAAAGATATTGACGAGTGTGAGAGTGGTATTCATAACTGCCTCCCCGATTTTATCTGTCAGAATACTCTGGGATCCTTCCGCTG
CCGACCCAAGCTACAGTGCAAGAGTGGCTTTATACAAGATGCTCTAGGCAACTGTATTGATATCAATGAGTGTTTGAGTATCAGTGCCCC
GTGCCCTATCGGGCATACATGCATCAACACAGAGGGCTCCTACACGTGCCAGAAGAACGTGCCCAACTGTGGCCGTGGCTACCATCTCAA
CGAGGAGGGAACGCGCTGTGTTGATGTGGACGAGTGCGCGCCACCTGCTGAGCCCTGTGGGAAGGGACATCGCTGCGTGAACTCTCCCGG
CAGTTTCCGCTGCGAATGCAAGACGGGTTACTATTTTGACGGCATCAGCAGGATGTGTGTCGATGTCAACGAGTGCCAGCGCTACCCCGG
GCGCCTGTGTGGCCACAAGTGCGAGAACACGCTGGGCTCCTACCTCTGCAGCTGTTCCGTGGGCTTCCGGCTCTCTGTGGATGGCAGGTC
ATGTGAAGACATCAATGAGTGCAGCAGCAGCCCCTGTAGCCAGGAGTGTGCCAACGTCTACGGCTCCTACCAGTGTTACTGCCGGCGAGG
CTACCAGCTCAGCGATGTGGATGGAGTCACCTGTGAAGACATCGACGAGTGCGCCCTGCCCACCGGGGGCCACATCTGCTCCTACCGCTG
CATCAACATCCCTGGAAGCTTCCAGTGCAGCTGCCCCTCGTCTGGCTACAGGCTGGCCCCCAATGGCCGCAACTGCCAAGACATTGATGA
GTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGA
GAACTACCGCCGCTCCGCAGCCACCCGCTGTGAGCGCTTGCCTTGCCATGAGAATCGGGAGTGCTCCAAGCTGCCTCTGAGAATAACCTA
CTACCACCTCTCTTTCCCCACCAACATCCAAGCGCCCGCGGTGGTTTTCCGCATGGGCCCCTCCAGTGCTGTCCCCGGGGACAGCATGCA
GCTGGCCATCACCGGCGGCAATGAGGAGGGCTTTTTCACCACCCGGAAGGTGAGCCCCCACAGTGGGGTGGTGGCCCTCACCAAGCCTGT
CCCCGAGCCCAGGGACTTGCTCCTGACCGTCAAGATGGATCTCTCTCGCCACGGCACCGTCAGCTCCTTTGTGGCCAAGCTTTTCATCTT
TGTGTCTGCAGAGCTCTGAGCACTCGCTTCGCGTCGCGGGGTCTCCCTCCTGTTGCTTTCCTAACCCTGCCCTCCGGGGCGTTAATAAAG
TCTTAGCAAGCGTCCCACACAGTGA

>8370_8370_1_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000252934_FBLN1_chr22_45914562_ENST00000262722_length(amino acids)=787AA_BP=129
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRN
ACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTVDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLEEL
HCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFQACCVKSQETGDLDVGGLQETDKIIE
VEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTE
DNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYH
LNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDG
RSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDI
DECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKLPLRITYYHLSFPTNIQAPAVVFRMGPSSAVPGDS
MQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVKMDLSRHGTVSSFVAKLFIFVSAEL

--------------------------------------------------------------
>8370_8370_2_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000252934_FBLN1_chr22_45914562_ENST00000327858_length(transcript)=3378nt_BP=656nt
GGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGGC
GGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATCC
TACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGGC
GGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGCT
CTTCAAAGAGCAGCGGAACCGAGAAACAGCACCCAGGACTATCTTCCAAAGAGTTCTGGATATCCTAAAGAAATCTTCTCATGCTGTTGA
GCTTGCCTGCAGAGATCCATCCCAAGTGGAAAACCTGGCTTCCAGTCTGCAGTTAATAACAGAATGCTTCAGGTGTCTTCGCAATGCTTG
CATAGAGTGTTCTGTGAACCAGAATTCAATCAGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCG
AGTGGAACAGGAATCTCTGTTGACAGTGGACGCGGATGTCCTCCTGGAGGCCTGCTGTGCGGACGGACACCGGATGGCCACTCATCAGAA
GGACTGCTCGCTGCCATATGCTACGGAATCCAAAGAATGCAGGATGGTGCAGGAGCAGTGCTGCCACAGCCAGCTGGAGGAGCTGCACTG
TGCCACGGGCATCAGCCTGGCCAACGAGCAGGACCGCTGTGCCACGCCCCACGGTGACAACGCCAGCCTGGAGGCCACATTTGTGAAGAG
GTGCTGCCATTGCTGTCTGCTGGGGAGGGCGGCCCAGGCCCAGGGCCAGAGCTGCGAGTACAGCCTCATGGTTGGCTACCAGTGTGGACA
GGTCTTCCAGGCATGCTGTGTCAAGAGCCAGGAGACCGGAGATTTGGATGTCGGGGGCCTCCAAGAAACGGATAAGATCATTGAGGTTGA
GGAGGAACAAGAGGACCCATATCTGAATGACCGCTGCCGAGGAGGCGGGCCCTGCAAGCAGCAGTGCCGAGACACGGGTGACGAGGTGGT
CTGCTCCTGCTTCGTGGGCTACCAGCTGCTGTCTGATGGTGTCTCCTGTGAAGATGTCAATGAATGCATCACGGGCAGCCACAGCTGCCG
GCTTGGAGAATCCTGCATCAACACAGTGGGCTCTTTCCGCTGCCAGCGGGACAGCAGCTGCGGGACTGGCTATGAGCTCACAGAGGACAA
TAGCTGCAAAGATATTGACGAGTGTGAGAGTGGTATTCATAACTGCCTCCCCGATTTTATCTGTCAGAATACTCTGGGATCCTTCCGCTG
CCGACCCAAGCTACAGTGCAAGAGTGGCTTTATACAAGATGCTCTAGGCAACTGTATTGATATCAATGAGTGTTTGAGTATCAGTGCCCC
GTGCCCTATCGGGCATACATGCATCAACACAGAGGGCTCCTACACGTGCCAGAAGAACGTGCCCAACTGTGGCCGTGGCTACCATCTCAA
CGAGGAGGGAACGCGCTGTGTTGATGTGGACGAGTGCGCGCCACCTGCTGAGCCCTGTGGGAAGGGACATCGCTGCGTGAACTCTCCCGG
CAGTTTCCGCTGCGAATGCAAGACGGGTTACTATTTTGACGGCATCAGCAGGATGTGTGTCGATGTCAACGAGTGCCAGCGCTACCCCGG
GCGCCTGTGTGGCCACAAGTGCGAGAACACGCTGGGCTCCTACCTCTGCAGCTGTTCCGTGGGCTTCCGGCTCTCTGTGGATGGCAGGTC
ATGTGAAGACATCAATGAGTGCAGCAGCAGCCCCTGTAGCCAGGAGTGTGCCAACGTCTACGGCTCCTACCAGTGTTACTGCCGGCGAGG
CTACCAGCTCAGCGATGTGGATGGAGTCACCTGTGAAGACATCGACGAGTGCGCCCTGCCCACCGGGGGCCACATCTGCTCCTACCGCTG
CATCAACATCCCTGGAAGCTTCCAGTGCAGCTGCCCCTCGTCTGGCTACAGGCTGGCCCCCAATGGCCGCAACTGCCAAGACATTGATGA
GTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGA
GAACTACCGCCGCTCCGCAGCCACGCTCCAGCAGGAGAAGACAGACACGGTCCGCTGCATCAAGTCCTGCCGCCCCAACGATGTCACATG
CGTGTTCGACCCCGTGCACACCATCTCCCACACCGTCATCTCGCTGCCTACCTTCCGCGAGTTCACCCGCCCTGAAGAGATCATCTTCCT
CCGGGCCATCACGCCACCGCATCCTGCCAGCCAGGCTAACATCATCTTCGACATCACGGAAGGGAACCTGCGGGACTCTTTTGACATCAT
CAAGCGTTACATGGACGGCATGACCGTGGGTGTCGTGCGCCAGGTGCGGCCCATCGTGGGCCCATTTCATGCCGTCCTGAAGCTGGAGAT
GAACTATGTGGTCGGGGGCGTGGTCTCCCACCGAAATGTTGTCAACGTCCACATCTTCGTCTCTGAGTACTGGTTCTGAGGGCTGGTCTG
CCGCACAGCCGCAGGTGCACCTCCAGGCCAAATCATTGCTGCCAGTGACTGTGGTCTGTACTTGTTTATACCCTCAGACTTTTTTAATGT
TAGGTATTTGTAGCATTAGGCCAACATGTATTAAGCTGAGCCAGATGAATAAGTCCATCTGATGTATTTTCGGTGTTTAAAAAATGAGCC
CAGTTGCTCAACTGTTTGGTTGAAAACCTTGCTCATTTTTTAATGCGAAGGCTAAGTGTCACCCCCTTTCTCTGCCTCTGGCTGGGCCTT
GCTAAGGGCCAAGGAAAGAAAGACATTTTTTAGGGGGCAGCCAGTCCAAATGCCAAAAGAAGACCAGTTCTTGCCCTGATTGTATGAAAT
TTGACATTTTGGCACTTTTTTTTTTTTTTTGGCCAATCAGATTTTCTATGTTCTAAGGACATGGCTGCTGTAGAATAGCACAGACGTGGA
TGATAAATTATCCCCAGAAGCAGCATGACAGAATGCCTCGGGGAGCACTTGGAAGGGAAATTGCAGTTCTGTTGAAATAGAGGAAAATCC
CTTGGTAAAGACACAGCCTGTTAGGCTCGTGTGGGCCTCCAGTATGTTCACCAGGGGAATGGCTGGGATTTCTCGGCACTCTGCATCATC
CATCTTTTCTTATAGGTGGGAAAATAAACAACTTTGTGATCCTCCTGA

>8370_8370_2_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000252934_FBLN1_chr22_45914562_ENST00000327858_length(amino acids)=807AA_BP=129
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRN
ACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTVDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLEEL
HCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFQACCVKSQETGDLDVGGLQETDKIIE
VEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTE
DNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYH
LNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDG
RSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDI
DECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPNDVTCVFDPVHTISHTVISLPTFREFTRPEEII
FLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPFHAVLKLEMNYVVGGVVSHRNVVNVHIFVSEYWF

--------------------------------------------------------------
>8370_8370_3_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000252934_FBLN1_chr22_45914562_ENST00000340923_length(transcript)=2915nt_BP=656nt
GGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGGC
GGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATCC
TACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGGC
GGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGCT
CTTCAAAGAGCAGCGGAACCGAGAAACAGCACCCAGGACTATCTTCCAAAGAGTTCTGGATATCCTAAAGAAATCTTCTCATGCTGTTGA
GCTTGCCTGCAGAGATCCATCCCAAGTGGAAAACCTGGCTTCCAGTCTGCAGTTAATAACAGAATGCTTCAGGTGTCTTCGCAATGCTTG
CATAGAGTGTTCTGTGAACCAGAATTCAATCAGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCG
AGTGGAACAGGAATCTCTGTTGACAGTGGACGCGGATGTCCTCCTGGAGGCCTGCTGTGCGGACGGACACCGGATGGCCACTCATCAGAA
GGACTGCTCGCTGCCATATGCTACGGAATCCAAAGAATGCAGGATGGTGCAGGAGCAGTGCTGCCACAGCCAGCTGGAGGAGCTGCACTG
TGCCACGGGCATCAGCCTGGCCAACGAGCAGGACCGCTGTGCCACGCCCCACGGTGACAACGCCAGCCTGGAGGCCACATTTGTGAAGAG
GTGCTGCCATTGCTGTCTGCTGGGGAGGGCGGCCCAGGCCCAGGGCCAGAGCTGCGAGTACAGCCTCATGGTTGGCTACCAGTGTGGACA
GGTCTTCCAGGCATGCTGTGTCAAGAGCCAGGAGACCGGAGATTTGGATGTCGGGGGCCTCCAAGAAACGGATAAGATCATTGAGGTTGA
GGAGGAACAAGAGGACCCATATCTGAATGACCGCTGCCGAGGAGGCGGGCCCTGCAAGCAGCAGTGCCGAGACACGGGTGACGAGGTGGT
CTGCTCCTGCTTCGTGGGCTACCAGCTGCTGTCTGATGGTGTCTCCTGTGAAGATGTCAATGAATGCATCACGGGCAGCCACAGCTGCCG
GCTTGGAGAATCCTGCATCAACACAGTGGGCTCTTTCCGCTGCCAGCGGGACAGCAGCTGCGGGACTGGCTATGAGCTCACAGAGGACAA
TAGCTGCAAAGATATTGACGAGTGTGAGAGTGGTATTCATAACTGCCTCCCCGATTTTATCTGTCAGAATACTCTGGGATCCTTCCGCTG
CCGACCCAAGCTACAGTGCAAGAGTGGCTTTATACAAGATGCTCTAGGCAACTGTATTGATATCAATGAGTGTTTGAGTATCAGTGCCCC
GTGCCCTATCGGGCATACATGCATCAACACAGAGGGCTCCTACACGTGCCAGAAGAACGTGCCCAACTGTGGCCGTGGCTACCATCTCAA
CGAGGAGGGAACGCGCTGTGTTGATGTGGACGAGTGCGCGCCACCTGCTGAGCCCTGTGGGAAGGGACATCGCTGCGTGAACTCTCCCGG
CAGTTTCCGCTGCGAATGCAAGACGGGTTACTATTTTGACGGCATCAGCAGGATGTGTGTCGATGTCAACGAGTGCCAGCGCTACCCCGG
GCGCCTGTGTGGCCACAAGTGCGAGAACACGCTGGGCTCCTACCTCTGCAGCTGTTCCGTGGGCTTCCGGCTCTCTGTGGATGGCAGGTC
ATGTGAAGACATCAATGAGTGCAGCAGCAGCCCCTGTAGCCAGGAGTGTGCCAACGTCTACGGCTCCTACCAGTGTTACTGCCGGCGAGG
CTACCAGCTCAGCGATGTGGATGGAGTCACCTGTGAAGACATCGACGAGTGCGCCCTGCCCACCGGGGGCCACATCTGCTCCTACCGCTG
CATCAACATCCCTGGAAGCTTCCAGTGCAGCTGCCCCTCGTCTGGCTACAGGCTGGCCCCCAATGGCCGCAACTGCCAAGACATTGATGA
GTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGA
GAACTACCGCCGCTCCGCAGCCACATGATCGTAGGGAACTCTGCATGAGGCCATCGGTGCAGGCTGGAGAAGAGAAGGCAAGTTGGCAGG
AGTGGAGACCACGGGCATTTGAGCCACTTCCTCATGTAACTTAACTTGTGCCTTCAGGACCTGCTCAAGCCCGATCACGTATATACCACT
TCCATTTGATGATGGAATGCTGCTGTTCATGACCAACTTTATGGCTAGATGGGTCAGAAAGCACCCAGTTCATGATAGGCAGTTCAGGTC
ATATGGTGACTTGATGACCCAGAGTCAAACATTCAGTTTCCACCAAAGCCCAGTAACAGGCCAAGAGCTGTCTCTCAAAAGGAGAGTAGT
TATCTGCAGAAGATGGCAGGGCCTTGCTCCGAAAGCCTAGAGACCGCCACTGTGATTCACCTATGGGGGCCTGCCAAAGGCTGCAGCCAG
CATCCTTATCTGCCACTGACACCTCAAGCAACATTGGATCTGCTGGGTCATATGGCCCAAGTGGCAGAGCAACTTGCACAACAGCCTGGA
CCTGTCATAGAGCTTTCTCCTGTTCTGGACCCCACTCAAAACTGGCAGCCTTTCAGGTCACTCGATAAATGTGCTGGAGTAACACTCAAA
CGAGGAATGTGTTGCCTCCAAAATCCAATAGGCCC

>8370_8370_3_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000252934_FBLN1_chr22_45914562_ENST00000340923_length(amino acids)=670AA_BP=129
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRN
ACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTVDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLEEL
HCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFQACCVKSQETGDLDVGGLQETDKIIE
VEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTE
DNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYH
LNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDG
RSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDI
DECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAAT

--------------------------------------------------------------
>8370_8370_4_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000252934_FBLN1_chr22_45914562_ENST00000348697_length(transcript)=3377nt_BP=656nt
GGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGGC
GGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATCC
TACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGGC
GGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGCT
CTTCAAAGAGCAGCGGAACCGAGAAACAGCACCCAGGACTATCTTCCAAAGAGTTCTGGATATCCTAAAGAAATCTTCTCATGCTGTTGA
GCTTGCCTGCAGAGATCCATCCCAAGTGGAAAACCTGGCTTCCAGTCTGCAGTTAATAACAGAATGCTTCAGGTGTCTTCGCAATGCTTG
CATAGAGTGTTCTGTGAACCAGAATTCAATCAGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCG
AGTGGAACAGGAATCTCTGTTGACAGTGGACGCGGATGTCCTCCTGGAGGCCTGCTGTGCGGACGGACACCGGATGGCCACTCATCAGAA
GGACTGCTCGCTGCCATATGCTACGGAATCCAAAGAATGCAGGATGGTGCAGGAGCAGTGCTGCCACAGCCAGCTGGAGGAGCTGCACTG
TGCCACGGGCATCAGCCTGGCCAACGAGCAGGACCGCTGTGCCACGCCCCACGGTGACAACGCCAGCCTGGAGGCCACATTTGTGAAGAG
GTGCTGCCATTGCTGTCTGCTGGGGAGGGCGGCCCAGGCCCAGGGCCAGAGCTGCGAGTACAGCCTCATGGTTGGCTACCAGTGTGGACA
GGTCTTCCAGGCATGCTGTGTCAAGAGCCAGGAGACCGGAGATTTGGATGTCGGGGGCCTCCAAGAAACGGATAAGATCATTGAGGTTGA
GGAGGAACAAGAGGACCCATATCTGAATGACCGCTGCCGAGGAGGCGGGCCCTGCAAGCAGCAGTGCCGAGACACGGGTGACGAGGTGGT
CTGCTCCTGCTTCGTGGGCTACCAGCTGCTGTCTGATGGTGTCTCCTGTGAAGATGTCAATGAATGCATCACGGGCAGCCACAGCTGCCG
GCTTGGAGAATCCTGCATCAACACAGTGGGCTCTTTCCGCTGCCAGCGGGACAGCAGCTGCGGGACTGGCTATGAGCTCACAGAGGACAA
TAGCTGCAAAGATATTGACGAGTGTGAGAGTGGTATTCATAACTGCCTCCCCGATTTTATCTGTCAGAATACTCTGGGATCCTTCCGCTG
CCGACCCAAGCTACAGTGCAAGAGTGGCTTTATACAAGATGCTCTAGGCAACTGTATTGATATCAATGAGTGTTTGAGTATCAGTGCCCC
GTGCCCTATCGGGCATACATGCATCAACACAGAGGGCTCCTACACGTGCCAGAAGAACGTGCCCAACTGTGGCCGTGGCTACCATCTCAA
CGAGGAGGGAACGCGCTGTGTTGATGTGGACGAGTGCGCGCCACCTGCTGAGCCCTGTGGGAAGGGACATCGCTGCGTGAACTCTCCCGG
CAGTTTCCGCTGCGAATGCAAGACGGGTTACTATTTTGACGGCATCAGCAGGATGTGTGTCGATGTCAACGAGTGCCAGCGCTACCCCGG
GCGCCTGTGTGGCCACAAGTGCGAGAACACGCTGGGCTCCTACCTCTGCAGCTGTTCCGTGGGCTTCCGGCTCTCTGTGGATGGCAGGTC
ATGTGAAGACATCAATGAGTGCAGCAGCAGCCCCTGTAGCCAGGAGTGTGCCAACGTCTACGGCTCCTACCAGTGTTACTGCCGGCGAGG
CTACCAGCTCAGCGATGTGGATGGAGTCACCTGTGAAGACATCGACGAGTGCGCCCTGCCCACCGGGGGCCACATCTGCTCCTACCGCTG
CATCAACATCCCTGGAAGCTTCCAGTGCAGCTGCCCCTCGTCTGGCTACAGGCTGGCCCCCAATGGCCGCAACTGCCAAGACATTGATGA
GTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGA
GAACTACCGCCGCTCCGCAGCCACGCAGAAATCCAAGAAGGGAAGGCAGAACACCCCAGCGGGATCAAGTAAAGAGGACTGCAGGGTTCT
TCCATGGAAGCAGGGGTTGGAGGATACCCACCTTGATGCCTATCTCCCATGTTGCAGGAGATTCACCCGCCCTGAAGAGATCATCTTCCT
CCGGGCCATCACGCCACCGCATCCTGCCAGCCAGGCTAACATCATCTTCGACATCACGGAAGGGAACCTGCGGGACTCTTTTGACATCAT
CAAGCGTTACATGGACGGCATGACCGTGGGTGTCGTGCGCCAGGTGCGGCCCATCGTGGGCCCATTTCATGCCGTCCTGAAGCTGGAGAT
GAACTATGTGGTCGGGGGCGTGGTCTCCCACCGAAATGTTGTCAACGTCCACATCTTCGTCTCTGAGTACTGGTTCTGAGGGCTGGTCTG
CCGCACAGCCGCAGGTGCACCTCCAGGCCAAATCATTGCTGCCAGTGACTGTGGTCTGTACTTGTTTATACCCTCAGACTTTTTTAATGT
TAGGTATTTGTAGCATTAGGCCAACATGTATTAAGCTGAGCCAGATGAATAAGTCCATCTGATGTATTTTCGGTGTTTAAAAAATGAGCC
CAGTTGCTCAACTGTTTGGTTGAAAACCTTGCTCATTTTTTAATGCGAAGGCTAAGTGTCACCCCCTTTCTCTGCCTCTGGCTGGGCCTT
GCTAAGGGCCAAGGAAAGAAAGACATTTTTTAGGGGGCAGCCAGTCCAAATGCCAAAAGAAGACCAGTTCTTGCCCTGATTGTATGAAAT
TTGACATTTTGGCACTTTTTTTTTTTTTTTGGCCAATCAGATTTTCTATGTTCTAAGGACATGGCTGCTGTAGAATAGCACAGACGTGGA
TGATAAATTATCCCCAGAAGCAGCATGACAGAATGCCTCGGGGAGCACTTGGAAGGGAAATTGCAGTTCTGTTGAAATAGAGGAAAATCC
CTTGGTAAAGACACAGCCTGTTAGGCTCGTGTGGGCCTCCAGTATGTTCACCAGGGGAATGGCTGGGATTTCTCGGCACTCTGCATCATC
CATCTTTTCTTATAGGTGGGAAAATAAACAACTTTGTGATCCTCCTG

>8370_8370_4_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000252934_FBLN1_chr22_45914562_ENST00000348697_length(amino acids)=807AA_BP=129
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRN
ACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTVDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLEEL
HCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFQACCVKSQETGDLDVGGLQETDKIIE
VEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTE
DNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYH
LNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDG
RSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDI
DECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGSSKEDCRVLPWKQGLEDTHLDAYLPCCRRFTRPEEII
FLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPFHAVLKLEMNYVVGGVVSHRNVVNVHIFVSEYWF

--------------------------------------------------------------
>8370_8370_5_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000252934_FBLN1_chr22_45914562_ENST00000402984_length(transcript)=2829nt_BP=656nt
GGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGGC
GGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATCC
TACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGGC
GGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGCT
CTTCAAAGAGCAGCGGAACCGAGAAACAGCACCCAGGACTATCTTCCAAAGAGTTCTGGATATCCTAAAGAAATCTTCTCATGCTGTTGA
GCTTGCCTGCAGAGATCCATCCCAAGTGGAAAACCTGGCTTCCAGTCTGCAGTTAATAACAGAATGCTTCAGGTGTCTTCGCAATGCTTG
CATAGAGTGTTCTGTGAACCAGAATTCAATCAGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCG
AGTGGAACAGGAATCTCTGTTGACAGTGGACGCGGATGTCCTCCTGGAGGCCTGCTGTGCGGACGGACACCGGATGGCCACTCATCAGAA
GGACTGCTCGCTGCCATATGCTACGGAATCCAAAGAATGCAGAGCCGTGGGGTTGGCCTCACTGTGCCAGGACCTGAATGGGGCGTGGGC
AGTATGGAAAGTGGGAAGAGCATCCCAGGCCGAGGGAACAGCCAGCGCAAGAGCCCAGAGGAGAGGGATGGTGCAGGAGCAGTGCTGCCA
CAGCCAGCTGGAGGAGCTGCACTGTGCCACGGGCATCAGCCTGGCCAACGAGCAGGACCGCTGTGCCACGCCCCACGGTGACAACGCCAG
CCTGGAGGCCACATTTGTGAAGAGGTGCTGCCATTGCTGTCTGCTGGGGAGGGCGGCCCAGGCCCAGGGCCAGAGCTGCGAGTACAGCCT
CATGGTTGGCTACCAGTGTGGACAGGTCTTCCAGGCATGCTGTGTCAAGAGCCAGGAGACCGGAGATTTGGATGTCGGGGGCCTCCAAGA
AACGGATAAGATCATTGAGGTTGAGGAGGAACAAGAGGACCCATATCTGAATGACCGCTGCCGAGGAGGCGGGCCCTGCAAGCAGCAGTG
CCGAGACACGGGTGACGAGGTGGTCTGCTCCTGCTTCGTGGGCTACCAGCTGCTGTCTGATGGTGTCTCCTGTGAAGATGTCAATGAATG
CATCACGGGCAGCCACAGCTGCCGGCTTGGAGAATCCTGCATCAACACAGTGGGCTCTTTCCGCTGCCAGCGGGACAGCAGCTGCGGGAC
TGGCTATGAGCTCACAGAGGACAATAGCTGCAAAGATATTGACGAGTGTGAGAGTGGTATTCATAACTGCCTCCCCGATTTTATCTGTCA
GAATACTCTGGGATCCTTCCGCTGCCGACCCAAGCTACAGTGCAAGAGTGGCTTTATACAAGATGCTCTAGGCAACTGTATTGATATCAA
TGAGTGTTTGAGTATCAGTGCCCCGTGCCCTATCGGGCATACATGCATCAACACAGAGGGCTCCTACACGTGCCAGAAGAACGTGCCCAA
CTGTGGCCGTGGCTACCATCTCAACGAGGAGGGAACGCGCTGTGTTGATGTGGACGAGTGCGCGCCACCTGCTGAGCCCTGTGGGAAGGG
ACATCGCTGCGTGAACTCTCCCGGCAGTTTCCGCTGCGAATGCAAGACGGGTTACTATTTTGACGGCATCAGCAGGATGTGTGTCGATGT
CAACGAGTGCCAGCGCTACCCCGGGCGCCTGTGTGGCCACAAGTGCGAGAACACGCTGGGCTCCTACCTCTGCAGCTGTTCCGTGGGCTT
CCGGCTCTCTGTGGATGGCAGGTCATGTGAAGACATCAATGAGTGCAGCAGCAGCCCCTGTAGCCAGGAGTGTGCCAACGTCTACGGCTC
CTACCAGTGTTACTGCCGGCGAGGCTACCAGCTCAGCGATGTGGATGGAGTCACCTGTGAAGACATCGACGAGTGCGCCCTGCCCACCGG
GGGCCACATCTGCTCCTACCGCTGCATCAACATCCCTGGAAGCTTCCAGTGCAGCTGCCCCTCGTCTGGCTACAGGCTGGCCCCCAATGG
CCGCAACTGCCAAGACATTGATGAGTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCG
CTGCCTGGCCTTCGAGTGCCCTGAGAACTACCGCCGCTCCGCAGCCACCCGCTGTGAGCGCTTGCCTTGCCATGAGAATCGGGAGTGCTC
CAAGCTGCCTCTGAGAATAACCTACTACCACCTCTCTTTCCCCACCAACATCCAAGCGCCCGCGGTGGTTTTCCGCATGGGCCCCTCCAG
TGCTGTCCCCGGGGACAGCATGCAGCTGGCCATCACCGGCGGCAATGAGGAGGGCTTTTTCACCACCCGGAAGGTGAGCCCCCACAGTGG
GGTGGTGGCCCTCACCAAGCCTGTCCCCGAGCCCAGGGACTTGCTCCTGACCGTCAAGATGGATCTCTCTCGCCACGGCACCGTCAGCTC
CTTTGTGGCCAAGCTTTTCATCTTTGTGTCTGCAGAGCTCTGAGCACTCGCTTCGCGTCGCGGGGTCTCCCTCCTGTTGCTTTCCTAACC
CTGCCCTCCGGGGCGTTAATAAAGTCTTAGCAAGCGTCC

>8370_8370_5_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000252934_FBLN1_chr22_45914562_ENST00000402984_length(amino acids)=825AA_BP=129
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRN
ACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTVDADVLLEACCADGHRMATHQKDCSLPYATESKECRAVGLASLCQDLNGA
WAVWKVGRASQAEGTASARAQRRGMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEY
SLMVGYQCGQVFQACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVN
ECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCID
INECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV
DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALP
TGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRE
CSKLPLRITYYHLSFPTNIQAPAVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVKMDLSRHGTV
SSFVAKLFIFVSAEL

--------------------------------------------------------------
>8370_8370_6_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000252934_FBLN1_chr22_45914562_ENST00000442170_length(transcript)=3092nt_BP=656nt
GGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGGC
GGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATCC
TACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGGC
GGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGCT
CTTCAAAGAGCAGCGGAACCGAGAAACAGCACCCAGGACTATCTTCCAAAGAGTTCTGGATATCCTAAAGAAATCTTCTCATGCTGTTGA
GCTTGCCTGCAGAGATCCATCCCAAGTGGAAAACCTGGCTTCCAGTCTGCAGTTAATAACAGAATGCTTCAGGTGTCTTCGCAATGCTTG
CATAGAGTGTTCTGTGAACCAGAATTCAATCAGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCG
AGTGGAACAGGAATCTCTGTTGACAGTGGACGCGGATGTCCTCCTGGAGGCCTGCTGTGCGGACGGACACCGGATGGCCACTCATCAGAA
GGACTGCTCGCTGCCATATGCTACGGAATCCAAAGAATGCAGGATGGTGCAGGAGCAGTGCTGCCACAGCCAGCTGGAGGAGCTGCACTG
TGCCACGGGCATCAGCCTGGCCAACGAGCAGGACCGCTGTGCCACGCCCCACGGTGACAACGCCAGCCTGGAGGCCACATTTGTGAAGAG
GTGCTGCCATTGCTGTCTGCTGGGGAGGGCGGCCCAGGCCCAGGGCCAGAGCTGCGAGTACAGCCTCATGGTTGGCTACCAGTGTGGACA
GGTCTTCCAGGCATGCTGTGTCAAGAGCCAGGAGACCGGAGATTTGGATGTCGGGGGCCTCCAAGAAACGGATAAGATCATTGAGGTTGA
GGAGGAACAAGAGGACCCATATCTGAATGACCGCTGCCGAGGAGGCGGGCCCTGCAAGCAGCAGTGCCGAGACACGGGTGACGAGGTGGT
CTGCTCCTGCTTCGTGGGCTACCAGCTGCTGTCTGATGGTGTCTCCTGTGAAGATGTCAATGAATGCATCACGGGCAGCCACAGCTGCCG
GCTTGGAGAATCCTGCATCAACACAGTGGGCTCTTTCCGCTGCCAGCGGGACAGCAGCTGCGGGACTGGCTATGAGCTCACAGAGGACAA
TAGCTGCAAAGATATTGACGAGTGTGAGAGTGGTATTCATAACTGCCTCCCCGATTTTATCTGTCAGAATACTCTGGGATCCTTCCGCTG
CCGACCCAAGCTACAGTGCAAGAGTGGCTTTATACAAGATGCTCTAGGCAACTGTATTGATATCAATGAGTGTTTGAGTATCAGTGCCCC
GTGCCCTATCGGGCATACATGCATCAACACAGAGGGCTCCTACACGTGCCAGAAGAACGTGCCCAACTGTGGCCGTGGCTACCATCTCAA
CGAGGAGGGAACGCGCTGTGTTGATGTGGACGAGTGCGCGCCACCTGCTGAGCCCTGTGGGAAGGGACATCGCTGCGTGAACTCTCCCGG
CAGTTTCCGCTGCGAATGCAAGACGGGTTACTATTTTGACGGCATCAGCAGGATGTGTGTCGATGTCAACGAGTGCCAGCGCTACCCCGG
GCGCCTGTGTGGCCACAAGTGCGAGAACACGCTGGGCTCCTACCTCTGCAGCTGTTCCGTGGGCTTCCGGCTCTCTGTGGATGGCAGGTC
ATGTGAAGACATCAATGAGTGCAGCAGCAGCCCCTGTAGCCAGGAGTGTGCCAACGTCTACGGCTCCTACCAGTGTTACTGCCGGCGAGG
CTACCAGCTCAGCGATGTGGATGGAGTCACCTGTGAAGACATCGACGAGTGCGCCCTGCCCACCGGGGGCCACATCTGCTCCTACCGCTG
CATCAACATCCCTGGAAGCTTCCAGTGCAGCTGCCCCTCGTCTGGCTACAGGCTGGCCCCCAATGGCCGCAACTGCCAAGACATTGATGA
GTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGA
GAACTACCGCCGCTCCGCAGCCACGCAGAAATCCAAGAAGGGAAGGCAGAACACCCCAGCGGGATCAAGTAAAGAGGACTGCAGGGTTCT
TCCATGGAAGCAGGGGTTGGAGGATACCCACCTTGATGCCTAGTGAGGAAGATGGACCTGGACAGACAGTCAGCTCCACACCTTGCGCTG
AGCAGCTGTGATTGTGCCACGGGAGCATGAGCCCTTTTCCCCACGGCCCTTGCCACTGTCTCCTGGCCCTCTCTCTGATCATGCCAGGTT
TGCACCAGCCTCGAGTCTCCCATGTTGTAGTACATTCTCCAAGATGCAGCCCAGGAGCCTCTCTGAAGGACCAGTCTGGTTACGATGGTC
TGAGCTTCCTTAGAACCTTCCATGGTTGTCTTTTCCCAGCAGATGAAGCATAGCCTCCTTGGAATGGCATGGGAGGCCTGGCCTGATCTG
GCCTCTGCCCACCCTTTGAGCTGCACCTGCCCCACCCCAGCTCATCCATGTGCTTGTACCCTGGCCCCACGGGGAGGCTTGCCCTTCCCT
GAATCTGCCTTCTTGTGGCTTTAGCATGTGCCATGCTGTCCCCCTGCAGACTGCCATTCTCCTTGCAGACTTGGCTCAGAAGTCACCTCC
TCAGTGCAGTTAGCCTGAGCTCCCCTGGCCCCAGGTGCCTCCATCAGAGCATTTACCCCATTGTGTTGTGGCTGTTCCTTAACGTCCCCA
CTAGCCAGGCTCTTTGAGGGCAGGGATTGTGTCTGGTTAATTTCTGTATTCTCTGCAACTTTGCAATGTTTGGCTTGAAGAAGGAGCTCA
GTAAACATCTGAATAAACATGCAGGTTGATGG

>8370_8370_6_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000252934_FBLN1_chr22_45914562_ENST00000442170_length(amino acids)=705AA_BP=129
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRN
ACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTVDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLEEL
HCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFQACCVKSQETGDLDVGGLQETDKIIE
VEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTE
DNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYH
LNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDG
RSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDI
DECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGSSKEDCRVLPWKQGLEDTHLDA

--------------------------------------------------------------
>8370_8370_7_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000381061_FBLN1_chr22_45914562_ENST00000262722_length(transcript)=2534nt_BP=465nt
AGGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGG
CGGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATC
CTACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGG
CGGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGC
TCTTCAAAGAGCAGCGGAACCGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCGAGTGGAACAGG
AATCTCTGTTGACAGTGGACGCGGATGTCCTCCTGGAGGCCTGCTGTGCGGACGGACACCGGATGGCCACTCATCAGAAGGACTGCTCGC
TGCCATATGCTACGGAATCCAAAGAATGCAGGATGGTGCAGGAGCAGTGCTGCCACAGCCAGCTGGAGGAGCTGCACTGTGCCACGGGCA
TCAGCCTGGCCAACGAGCAGGACCGCTGTGCCACGCCCCACGGTGACAACGCCAGCCTGGAGGCCACATTTGTGAAGAGGTGCTGCCATT
GCTGTCTGCTGGGGAGGGCGGCCCAGGCCCAGGGCCAGAGCTGCGAGTACAGCCTCATGGTTGGCTACCAGTGTGGACAGGTCTTCCAGG
CATGCTGTGTCAAGAGCCAGGAGACCGGAGATTTGGATGTCGGGGGCCTCCAAGAAACGGATAAGATCATTGAGGTTGAGGAGGAACAAG
AGGACCCATATCTGAATGACCGCTGCCGAGGAGGCGGGCCCTGCAAGCAGCAGTGCCGAGACACGGGTGACGAGGTGGTCTGCTCCTGCT
TCGTGGGCTACCAGCTGCTGTCTGATGGTGTCTCCTGTGAAGATGTCAATGAATGCATCACGGGCAGCCACAGCTGCCGGCTTGGAGAAT
CCTGCATCAACACAGTGGGCTCTTTCCGCTGCCAGCGGGACAGCAGCTGCGGGACTGGCTATGAGCTCACAGAGGACAATAGCTGCAAAG
ATATTGACGAGTGTGAGAGTGGTATTCATAACTGCCTCCCCGATTTTATCTGTCAGAATACTCTGGGATCCTTCCGCTGCCGACCCAAGC
TACAGTGCAAGAGTGGCTTTATACAAGATGCTCTAGGCAACTGTATTGATATCAATGAGTGTTTGAGTATCAGTGCCCCGTGCCCTATCG
GGCATACATGCATCAACACAGAGGGCTCCTACACGTGCCAGAAGAACGTGCCCAACTGTGGCCGTGGCTACCATCTCAACGAGGAGGGAA
CGCGCTGTGTTGATGTGGACGAGTGCGCGCCACCTGCTGAGCCCTGTGGGAAGGGACATCGCTGCGTGAACTCTCCCGGCAGTTTCCGCT
GCGAATGCAAGACGGGTTACTATTTTGACGGCATCAGCAGGATGTGTGTCGATGTCAACGAGTGCCAGCGCTACCCCGGGCGCCTGTGTG
GCCACAAGTGCGAGAACACGCTGGGCTCCTACCTCTGCAGCTGTTCCGTGGGCTTCCGGCTCTCTGTGGATGGCAGGTCATGTGAAGACA
TCAATGAGTGCAGCAGCAGCCCCTGTAGCCAGGAGTGTGCCAACGTCTACGGCTCCTACCAGTGTTACTGCCGGCGAGGCTACCAGCTCA
GCGATGTGGATGGAGTCACCTGTGAAGACATCGACGAGTGCGCCCTGCCCACCGGGGGCCACATCTGCTCCTACCGCTGCATCAACATCC
CTGGAAGCTTCCAGTGCAGCTGCCCCTCGTCTGGCTACAGGCTGGCCCCCAATGGCCGCAACTGCCAAGACATTGATGAGTGTGTGACTG
GCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTACCGCC
GCTCCGCAGCCACCCGCTGTGAGCGCTTGCCTTGCCATGAGAATCGGGAGTGCTCCAAGCTGCCTCTGAGAATAACCTACTACCACCTCT
CTTTCCCCACCAACATCCAAGCGCCCGCGGTGGTTTTCCGCATGGGCCCCTCCAGTGCTGTCCCCGGGGACAGCATGCAGCTGGCCATCA
CCGGCGGCAATGAGGAGGGCTTTTTCACCACCCGGAAGGTGAGCCCCCACAGTGGGGTGGTGGCCCTCACCAAGCCTGTCCCCGAGCCCA
GGGACTTGCTCCTGACCGTCAAGATGGATCTCTCTCGCCACGGCACCGTCAGCTCCTTTGTGGCCAAGCTTTTCATCTTTGTGTCTGCAG
AGCTCTGAGCACTCGCTTCGCGTCGCGGGGTCTCCCTCCTGTTGCTTTCCTAACCCTGCCCTCCGGGGCGTTAATAAAGTCTTAGCAAGC
GTCCCACACAGTGA

>8370_8370_7_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000381061_FBLN1_chr22_45914562_ENST00000262722_length(amino acids)=723AA_BP=65
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRNLDTIGVAVDLILLFRELRVEQESLLTVDADVLLEACCADGHRMATHQKDC
SLPYATESKECRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVF
QACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLG
ESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCP
IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL
CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN
IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKLPLRITYYH
LSFPTNIQAPAVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVKMDLSRHGTVSSFVAKLFIFVS
AEL

--------------------------------------------------------------
>8370_8370_8_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000381061_FBLN1_chr22_45914562_ENST00000327858_length(transcript)=3187nt_BP=465nt
AGGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGG
CGGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATC
CTACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGG
CGGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGC
TCTTCAAAGAGCAGCGGAACCGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCGAGTGGAACAGG
AATCTCTGTTGACAGTGGACGCGGATGTCCTCCTGGAGGCCTGCTGTGCGGACGGACACCGGATGGCCACTCATCAGAAGGACTGCTCGC
TGCCATATGCTACGGAATCCAAAGAATGCAGGATGGTGCAGGAGCAGTGCTGCCACAGCCAGCTGGAGGAGCTGCACTGTGCCACGGGCA
TCAGCCTGGCCAACGAGCAGGACCGCTGTGCCACGCCCCACGGTGACAACGCCAGCCTGGAGGCCACATTTGTGAAGAGGTGCTGCCATT
GCTGTCTGCTGGGGAGGGCGGCCCAGGCCCAGGGCCAGAGCTGCGAGTACAGCCTCATGGTTGGCTACCAGTGTGGACAGGTCTTCCAGG
CATGCTGTGTCAAGAGCCAGGAGACCGGAGATTTGGATGTCGGGGGCCTCCAAGAAACGGATAAGATCATTGAGGTTGAGGAGGAACAAG
AGGACCCATATCTGAATGACCGCTGCCGAGGAGGCGGGCCCTGCAAGCAGCAGTGCCGAGACACGGGTGACGAGGTGGTCTGCTCCTGCT
TCGTGGGCTACCAGCTGCTGTCTGATGGTGTCTCCTGTGAAGATGTCAATGAATGCATCACGGGCAGCCACAGCTGCCGGCTTGGAGAAT
CCTGCATCAACACAGTGGGCTCTTTCCGCTGCCAGCGGGACAGCAGCTGCGGGACTGGCTATGAGCTCACAGAGGACAATAGCTGCAAAG
ATATTGACGAGTGTGAGAGTGGTATTCATAACTGCCTCCCCGATTTTATCTGTCAGAATACTCTGGGATCCTTCCGCTGCCGACCCAAGC
TACAGTGCAAGAGTGGCTTTATACAAGATGCTCTAGGCAACTGTATTGATATCAATGAGTGTTTGAGTATCAGTGCCCCGTGCCCTATCG
GGCATACATGCATCAACACAGAGGGCTCCTACACGTGCCAGAAGAACGTGCCCAACTGTGGCCGTGGCTACCATCTCAACGAGGAGGGAA
CGCGCTGTGTTGATGTGGACGAGTGCGCGCCACCTGCTGAGCCCTGTGGGAAGGGACATCGCTGCGTGAACTCTCCCGGCAGTTTCCGCT
GCGAATGCAAGACGGGTTACTATTTTGACGGCATCAGCAGGATGTGTGTCGATGTCAACGAGTGCCAGCGCTACCCCGGGCGCCTGTGTG
GCCACAAGTGCGAGAACACGCTGGGCTCCTACCTCTGCAGCTGTTCCGTGGGCTTCCGGCTCTCTGTGGATGGCAGGTCATGTGAAGACA
TCAATGAGTGCAGCAGCAGCCCCTGTAGCCAGGAGTGTGCCAACGTCTACGGCTCCTACCAGTGTTACTGCCGGCGAGGCTACCAGCTCA
GCGATGTGGATGGAGTCACCTGTGAAGACATCGACGAGTGCGCCCTGCCCACCGGGGGCCACATCTGCTCCTACCGCTGCATCAACATCC
CTGGAAGCTTCCAGTGCAGCTGCCCCTCGTCTGGCTACAGGCTGGCCCCCAATGGCCGCAACTGCCAAGACATTGATGAGTGTGTGACTG
GCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTACCGCC
GCTCCGCAGCCACGCTCCAGCAGGAGAAGACAGACACGGTCCGCTGCATCAAGTCCTGCCGCCCCAACGATGTCACATGCGTGTTCGACC
CCGTGCACACCATCTCCCACACCGTCATCTCGCTGCCTACCTTCCGCGAGTTCACCCGCCCTGAAGAGATCATCTTCCTCCGGGCCATCA
CGCCACCGCATCCTGCCAGCCAGGCTAACATCATCTTCGACATCACGGAAGGGAACCTGCGGGACTCTTTTGACATCATCAAGCGTTACA
TGGACGGCATGACCGTGGGTGTCGTGCGCCAGGTGCGGCCCATCGTGGGCCCATTTCATGCCGTCCTGAAGCTGGAGATGAACTATGTGG
TCGGGGGCGTGGTCTCCCACCGAAATGTTGTCAACGTCCACATCTTCGTCTCTGAGTACTGGTTCTGAGGGCTGGTCTGCCGCACAGCCG
CAGGTGCACCTCCAGGCCAAATCATTGCTGCCAGTGACTGTGGTCTGTACTTGTTTATACCCTCAGACTTTTTTAATGTTAGGTATTTGT
AGCATTAGGCCAACATGTATTAAGCTGAGCCAGATGAATAAGTCCATCTGATGTATTTTCGGTGTTTAAAAAATGAGCCCAGTTGCTCAA
CTGTTTGGTTGAAAACCTTGCTCATTTTTTAATGCGAAGGCTAAGTGTCACCCCCTTTCTCTGCCTCTGGCTGGGCCTTGCTAAGGGCCA
AGGAAAGAAAGACATTTTTTAGGGGGCAGCCAGTCCAAATGCCAAAAGAAGACCAGTTCTTGCCCTGATTGTATGAAATTTGACATTTTG
GCACTTTTTTTTTTTTTTTGGCCAATCAGATTTTCTATGTTCTAAGGACATGGCTGCTGTAGAATAGCACAGACGTGGATGATAAATTAT
CCCCAGAAGCAGCATGACAGAATGCCTCGGGGAGCACTTGGAAGGGAAATTGCAGTTCTGTTGAAATAGAGGAAAATCCCTTGGTAAAGA
CACAGCCTGTTAGGCTCGTGTGGGCCTCCAGTATGTTCACCAGGGGAATGGCTGGGATTTCTCGGCACTCTGCATCATCCATCTTTTCTT
ATAGGTGGGAAAATAAACAACTTTGTGATCCTCCTGA

>8370_8370_8_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000381061_FBLN1_chr22_45914562_ENST00000327858_length(amino acids)=743AA_BP=65
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRNLDTIGVAVDLILLFRELRVEQESLLTVDADVLLEACCADGHRMATHQKDC
SLPYATESKECRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVF
QACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLG
ESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCP
IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL
CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN
IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPNDVTCVF
DPVHTISHTVISLPTFREFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPFHAVLKLEMNY
VVGGVVSHRNVVNVHIFVSEYWF

--------------------------------------------------------------
>8370_8370_9_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000381061_FBLN1_chr22_45914562_ENST00000340923_length(transcript)=2724nt_BP=465nt
AGGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGG
CGGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATC
CTACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGG
CGGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGC
TCTTCAAAGAGCAGCGGAACCGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCGAGTGGAACAGG
AATCTCTGTTGACAGTGGACGCGGATGTCCTCCTGGAGGCCTGCTGTGCGGACGGACACCGGATGGCCACTCATCAGAAGGACTGCTCGC
TGCCATATGCTACGGAATCCAAAGAATGCAGGATGGTGCAGGAGCAGTGCTGCCACAGCCAGCTGGAGGAGCTGCACTGTGCCACGGGCA
TCAGCCTGGCCAACGAGCAGGACCGCTGTGCCACGCCCCACGGTGACAACGCCAGCCTGGAGGCCACATTTGTGAAGAGGTGCTGCCATT
GCTGTCTGCTGGGGAGGGCGGCCCAGGCCCAGGGCCAGAGCTGCGAGTACAGCCTCATGGTTGGCTACCAGTGTGGACAGGTCTTCCAGG
CATGCTGTGTCAAGAGCCAGGAGACCGGAGATTTGGATGTCGGGGGCCTCCAAGAAACGGATAAGATCATTGAGGTTGAGGAGGAACAAG
AGGACCCATATCTGAATGACCGCTGCCGAGGAGGCGGGCCCTGCAAGCAGCAGTGCCGAGACACGGGTGACGAGGTGGTCTGCTCCTGCT
TCGTGGGCTACCAGCTGCTGTCTGATGGTGTCTCCTGTGAAGATGTCAATGAATGCATCACGGGCAGCCACAGCTGCCGGCTTGGAGAAT
CCTGCATCAACACAGTGGGCTCTTTCCGCTGCCAGCGGGACAGCAGCTGCGGGACTGGCTATGAGCTCACAGAGGACAATAGCTGCAAAG
ATATTGACGAGTGTGAGAGTGGTATTCATAACTGCCTCCCCGATTTTATCTGTCAGAATACTCTGGGATCCTTCCGCTGCCGACCCAAGC
TACAGTGCAAGAGTGGCTTTATACAAGATGCTCTAGGCAACTGTATTGATATCAATGAGTGTTTGAGTATCAGTGCCCCGTGCCCTATCG
GGCATACATGCATCAACACAGAGGGCTCCTACACGTGCCAGAAGAACGTGCCCAACTGTGGCCGTGGCTACCATCTCAACGAGGAGGGAA
CGCGCTGTGTTGATGTGGACGAGTGCGCGCCACCTGCTGAGCCCTGTGGGAAGGGACATCGCTGCGTGAACTCTCCCGGCAGTTTCCGCT
GCGAATGCAAGACGGGTTACTATTTTGACGGCATCAGCAGGATGTGTGTCGATGTCAACGAGTGCCAGCGCTACCCCGGGCGCCTGTGTG
GCCACAAGTGCGAGAACACGCTGGGCTCCTACCTCTGCAGCTGTTCCGTGGGCTTCCGGCTCTCTGTGGATGGCAGGTCATGTGAAGACA
TCAATGAGTGCAGCAGCAGCCCCTGTAGCCAGGAGTGTGCCAACGTCTACGGCTCCTACCAGTGTTACTGCCGGCGAGGCTACCAGCTCA
GCGATGTGGATGGAGTCACCTGTGAAGACATCGACGAGTGCGCCCTGCCCACCGGGGGCCACATCTGCTCCTACCGCTGCATCAACATCC
CTGGAAGCTTCCAGTGCAGCTGCCCCTCGTCTGGCTACAGGCTGGCCCCCAATGGCCGCAACTGCCAAGACATTGATGAGTGTGTGACTG
GCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTACCGCC
GCTCCGCAGCCACATGATCGTAGGGAACTCTGCATGAGGCCATCGGTGCAGGCTGGAGAAGAGAAGGCAAGTTGGCAGGAGTGGAGACCA
CGGGCATTTGAGCCACTTCCTCATGTAACTTAACTTGTGCCTTCAGGACCTGCTCAAGCCCGATCACGTATATACCACTTCCATTTGATG
ATGGAATGCTGCTGTTCATGACCAACTTTATGGCTAGATGGGTCAGAAAGCACCCAGTTCATGATAGGCAGTTCAGGTCATATGGTGACT
TGATGACCCAGAGTCAAACATTCAGTTTCCACCAAAGCCCAGTAACAGGCCAAGAGCTGTCTCTCAAAAGGAGAGTAGTTATCTGCAGAA
GATGGCAGGGCCTTGCTCCGAAAGCCTAGAGACCGCCACTGTGATTCACCTATGGGGGCCTGCCAAAGGCTGCAGCCAGCATCCTTATCT
GCCACTGACACCTCAAGCAACATTGGATCTGCTGGGTCATATGGCCCAAGTGGCAGAGCAACTTGCACAACAGCCTGGACCTGTCATAGA
GCTTTCTCCTGTTCTGGACCCCACTCAAAACTGGCAGCCTTTCAGGTCACTCGATAAATGTGCTGGAGTAACACTCAAACGAGGAATGTG
TTGCCTCCAAAATCCAATAGGCCC

>8370_8370_9_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000381061_FBLN1_chr22_45914562_ENST00000340923_length(amino acids)=606AA_BP=65
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRNLDTIGVAVDLILLFRELRVEQESLLTVDADVLLEACCADGHRMATHQKDC
SLPYATESKECRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVF
QACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLG
ESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCP
IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL
CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN
IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAAT

--------------------------------------------------------------
>8370_8370_10_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000381061_FBLN1_chr22_45914562_ENST00000348697_length(transcript)=3186nt_BP=465nt
AGGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGG
CGGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATC
CTACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGG
CGGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGC
TCTTCAAAGAGCAGCGGAACCGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCGAGTGGAACAGG
AATCTCTGTTGACAGTGGACGCGGATGTCCTCCTGGAGGCCTGCTGTGCGGACGGACACCGGATGGCCACTCATCAGAAGGACTGCTCGC
TGCCATATGCTACGGAATCCAAAGAATGCAGGATGGTGCAGGAGCAGTGCTGCCACAGCCAGCTGGAGGAGCTGCACTGTGCCACGGGCA
TCAGCCTGGCCAACGAGCAGGACCGCTGTGCCACGCCCCACGGTGACAACGCCAGCCTGGAGGCCACATTTGTGAAGAGGTGCTGCCATT
GCTGTCTGCTGGGGAGGGCGGCCCAGGCCCAGGGCCAGAGCTGCGAGTACAGCCTCATGGTTGGCTACCAGTGTGGACAGGTCTTCCAGG
CATGCTGTGTCAAGAGCCAGGAGACCGGAGATTTGGATGTCGGGGGCCTCCAAGAAACGGATAAGATCATTGAGGTTGAGGAGGAACAAG
AGGACCCATATCTGAATGACCGCTGCCGAGGAGGCGGGCCCTGCAAGCAGCAGTGCCGAGACACGGGTGACGAGGTGGTCTGCTCCTGCT
TCGTGGGCTACCAGCTGCTGTCTGATGGTGTCTCCTGTGAAGATGTCAATGAATGCATCACGGGCAGCCACAGCTGCCGGCTTGGAGAAT
CCTGCATCAACACAGTGGGCTCTTTCCGCTGCCAGCGGGACAGCAGCTGCGGGACTGGCTATGAGCTCACAGAGGACAATAGCTGCAAAG
ATATTGACGAGTGTGAGAGTGGTATTCATAACTGCCTCCCCGATTTTATCTGTCAGAATACTCTGGGATCCTTCCGCTGCCGACCCAAGC
TACAGTGCAAGAGTGGCTTTATACAAGATGCTCTAGGCAACTGTATTGATATCAATGAGTGTTTGAGTATCAGTGCCCCGTGCCCTATCG
GGCATACATGCATCAACACAGAGGGCTCCTACACGTGCCAGAAGAACGTGCCCAACTGTGGCCGTGGCTACCATCTCAACGAGGAGGGAA
CGCGCTGTGTTGATGTGGACGAGTGCGCGCCACCTGCTGAGCCCTGTGGGAAGGGACATCGCTGCGTGAACTCTCCCGGCAGTTTCCGCT
GCGAATGCAAGACGGGTTACTATTTTGACGGCATCAGCAGGATGTGTGTCGATGTCAACGAGTGCCAGCGCTACCCCGGGCGCCTGTGTG
GCCACAAGTGCGAGAACACGCTGGGCTCCTACCTCTGCAGCTGTTCCGTGGGCTTCCGGCTCTCTGTGGATGGCAGGTCATGTGAAGACA
TCAATGAGTGCAGCAGCAGCCCCTGTAGCCAGGAGTGTGCCAACGTCTACGGCTCCTACCAGTGTTACTGCCGGCGAGGCTACCAGCTCA
GCGATGTGGATGGAGTCACCTGTGAAGACATCGACGAGTGCGCCCTGCCCACCGGGGGCCACATCTGCTCCTACCGCTGCATCAACATCC
CTGGAAGCTTCCAGTGCAGCTGCCCCTCGTCTGGCTACAGGCTGGCCCCCAATGGCCGCAACTGCCAAGACATTGATGAGTGTGTGACTG
GCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTACCGCC
GCTCCGCAGCCACGCAGAAATCCAAGAAGGGAAGGCAGAACACCCCAGCGGGATCAAGTAAAGAGGACTGCAGGGTTCTTCCATGGAAGC
AGGGGTTGGAGGATACCCACCTTGATGCCTATCTCCCATGTTGCAGGAGATTCACCCGCCCTGAAGAGATCATCTTCCTCCGGGCCATCA
CGCCACCGCATCCTGCCAGCCAGGCTAACATCATCTTCGACATCACGGAAGGGAACCTGCGGGACTCTTTTGACATCATCAAGCGTTACA
TGGACGGCATGACCGTGGGTGTCGTGCGCCAGGTGCGGCCCATCGTGGGCCCATTTCATGCCGTCCTGAAGCTGGAGATGAACTATGTGG
TCGGGGGCGTGGTCTCCCACCGAAATGTTGTCAACGTCCACATCTTCGTCTCTGAGTACTGGTTCTGAGGGCTGGTCTGCCGCACAGCCG
CAGGTGCACCTCCAGGCCAAATCATTGCTGCCAGTGACTGTGGTCTGTACTTGTTTATACCCTCAGACTTTTTTAATGTTAGGTATTTGT
AGCATTAGGCCAACATGTATTAAGCTGAGCCAGATGAATAAGTCCATCTGATGTATTTTCGGTGTTTAAAAAATGAGCCCAGTTGCTCAA
CTGTTTGGTTGAAAACCTTGCTCATTTTTTAATGCGAAGGCTAAGTGTCACCCCCTTTCTCTGCCTCTGGCTGGGCCTTGCTAAGGGCCA
AGGAAAGAAAGACATTTTTTAGGGGGCAGCCAGTCCAAATGCCAAAAGAAGACCAGTTCTTGCCCTGATTGTATGAAATTTGACATTTTG
GCACTTTTTTTTTTTTTTTGGCCAATCAGATTTTCTATGTTCTAAGGACATGGCTGCTGTAGAATAGCACAGACGTGGATGATAAATTAT
CCCCAGAAGCAGCATGACAGAATGCCTCGGGGAGCACTTGGAAGGGAAATTGCAGTTCTGTTGAAATAGAGGAAAATCCCTTGGTAAAGA
CACAGCCTGTTAGGCTCGTGTGGGCCTCCAGTATGTTCACCAGGGGAATGGCTGGGATTTCTCGGCACTCTGCATCATCCATCTTTTCTT
ATAGGTGGGAAAATAAACAACTTTGTGATCCTCCTG

>8370_8370_10_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000381061_FBLN1_chr22_45914562_ENST00000348697_length(amino acids)=743AA_BP=65
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRNLDTIGVAVDLILLFRELRVEQESLLTVDADVLLEACCADGHRMATHQKDC
SLPYATESKECRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVF
QACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLG
ESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCP
IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL
CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN
IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGSSKEDCRVLPW
KQGLEDTHLDAYLPCCRRFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPFHAVLKLEMNY
VVGGVVSHRNVVNVHIFVSEYWF

--------------------------------------------------------------
>8370_8370_11_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000381061_FBLN1_chr22_45914562_ENST00000402984_length(transcript)=2638nt_BP=465nt
AGGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGG
CGGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATC
CTACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGG
CGGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGC
TCTTCAAAGAGCAGCGGAACCGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCGAGTGGAACAGG
AATCTCTGTTGACAGTGGACGCGGATGTCCTCCTGGAGGCCTGCTGTGCGGACGGACACCGGATGGCCACTCATCAGAAGGACTGCTCGC
TGCCATATGCTACGGAATCCAAAGAATGCAGAGCCGTGGGGTTGGCCTCACTGTGCCAGGACCTGAATGGGGCGTGGGCAGTATGGAAAG
TGGGAAGAGCATCCCAGGCCGAGGGAACAGCCAGCGCAAGAGCCCAGAGGAGAGGGATGGTGCAGGAGCAGTGCTGCCACAGCCAGCTGG
AGGAGCTGCACTGTGCCACGGGCATCAGCCTGGCCAACGAGCAGGACCGCTGTGCCACGCCCCACGGTGACAACGCCAGCCTGGAGGCCA
CATTTGTGAAGAGGTGCTGCCATTGCTGTCTGCTGGGGAGGGCGGCCCAGGCCCAGGGCCAGAGCTGCGAGTACAGCCTCATGGTTGGCT
ACCAGTGTGGACAGGTCTTCCAGGCATGCTGTGTCAAGAGCCAGGAGACCGGAGATTTGGATGTCGGGGGCCTCCAAGAAACGGATAAGA
TCATTGAGGTTGAGGAGGAACAAGAGGACCCATATCTGAATGACCGCTGCCGAGGAGGCGGGCCCTGCAAGCAGCAGTGCCGAGACACGG
GTGACGAGGTGGTCTGCTCCTGCTTCGTGGGCTACCAGCTGCTGTCTGATGGTGTCTCCTGTGAAGATGTCAATGAATGCATCACGGGCA
GCCACAGCTGCCGGCTTGGAGAATCCTGCATCAACACAGTGGGCTCTTTCCGCTGCCAGCGGGACAGCAGCTGCGGGACTGGCTATGAGC
TCACAGAGGACAATAGCTGCAAAGATATTGACGAGTGTGAGAGTGGTATTCATAACTGCCTCCCCGATTTTATCTGTCAGAATACTCTGG
GATCCTTCCGCTGCCGACCCAAGCTACAGTGCAAGAGTGGCTTTATACAAGATGCTCTAGGCAACTGTATTGATATCAATGAGTGTTTGA
GTATCAGTGCCCCGTGCCCTATCGGGCATACATGCATCAACACAGAGGGCTCCTACACGTGCCAGAAGAACGTGCCCAACTGTGGCCGTG
GCTACCATCTCAACGAGGAGGGAACGCGCTGTGTTGATGTGGACGAGTGCGCGCCACCTGCTGAGCCCTGTGGGAAGGGACATCGCTGCG
TGAACTCTCCCGGCAGTTTCCGCTGCGAATGCAAGACGGGTTACTATTTTGACGGCATCAGCAGGATGTGTGTCGATGTCAACGAGTGCC
AGCGCTACCCCGGGCGCCTGTGTGGCCACAAGTGCGAGAACACGCTGGGCTCCTACCTCTGCAGCTGTTCCGTGGGCTTCCGGCTCTCTG
TGGATGGCAGGTCATGTGAAGACATCAATGAGTGCAGCAGCAGCCCCTGTAGCCAGGAGTGTGCCAACGTCTACGGCTCCTACCAGTGTT
ACTGCCGGCGAGGCTACCAGCTCAGCGATGTGGATGGAGTCACCTGTGAAGACATCGACGAGTGCGCCCTGCCCACCGGGGGCCACATCT
GCTCCTACCGCTGCATCAACATCCCTGGAAGCTTCCAGTGCAGCTGCCCCTCGTCTGGCTACAGGCTGGCCCCCAATGGCCGCAACTGCC
AAGACATTGATGAGTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCT
TCGAGTGCCCTGAGAACTACCGCCGCTCCGCAGCCACCCGCTGTGAGCGCTTGCCTTGCCATGAGAATCGGGAGTGCTCCAAGCTGCCTC
TGAGAATAACCTACTACCACCTCTCTTTCCCCACCAACATCCAAGCGCCCGCGGTGGTTTTCCGCATGGGCCCCTCCAGTGCTGTCCCCG
GGGACAGCATGCAGCTGGCCATCACCGGCGGCAATGAGGAGGGCTTTTTCACCACCCGGAAGGTGAGCCCCCACAGTGGGGTGGTGGCCC
TCACCAAGCCTGTCCCCGAGCCCAGGGACTTGCTCCTGACCGTCAAGATGGATCTCTCTCGCCACGGCACCGTCAGCTCCTTTGTGGCCA
AGCTTTTCATCTTTGTGTCTGCAGAGCTCTGAGCACTCGCTTCGCGTCGCGGGGTCTCCCTCCTGTTGCTTTCCTAACCCTGCCCTCCGG
GGCGTTAATAAAGTCTTAGCAAGCGTCC

>8370_8370_11_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000381061_FBLN1_chr22_45914562_ENST00000402984_length(amino acids)=761AA_BP=65
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRNLDTIGVAVDLILLFRELRVEQESLLTVDADVLLEACCADGHRMATHQKDC
SLPYATESKECRAVGLASLCQDLNGAWAVWKVGRASQAEGTASARAQRRGMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLE
ATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFQACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRD
TGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNT
LGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHR
CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQ
CYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCL
AFECPENYRRSAATRCERLPCHENRECSKLPLRITYYHLSFPTNIQAPAVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSGVV
ALTKPVPEPRDLLLTVKMDLSRHGTVSSFVAKLFIFVSAEL

--------------------------------------------------------------
>8370_8370_12_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000381061_FBLN1_chr22_45914562_ENST00000442170_length(transcript)=2901nt_BP=465nt
AGGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGG
CGGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATC
CTACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGG
CGGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGC
TCTTCAAAGAGCAGCGGAACCGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCGAGTGGAACAGG
AATCTCTGTTGACAGTGGACGCGGATGTCCTCCTGGAGGCCTGCTGTGCGGACGGACACCGGATGGCCACTCATCAGAAGGACTGCTCGC
TGCCATATGCTACGGAATCCAAAGAATGCAGGATGGTGCAGGAGCAGTGCTGCCACAGCCAGCTGGAGGAGCTGCACTGTGCCACGGGCA
TCAGCCTGGCCAACGAGCAGGACCGCTGTGCCACGCCCCACGGTGACAACGCCAGCCTGGAGGCCACATTTGTGAAGAGGTGCTGCCATT
GCTGTCTGCTGGGGAGGGCGGCCCAGGCCCAGGGCCAGAGCTGCGAGTACAGCCTCATGGTTGGCTACCAGTGTGGACAGGTCTTCCAGG
CATGCTGTGTCAAGAGCCAGGAGACCGGAGATTTGGATGTCGGGGGCCTCCAAGAAACGGATAAGATCATTGAGGTTGAGGAGGAACAAG
AGGACCCATATCTGAATGACCGCTGCCGAGGAGGCGGGCCCTGCAAGCAGCAGTGCCGAGACACGGGTGACGAGGTGGTCTGCTCCTGCT
TCGTGGGCTACCAGCTGCTGTCTGATGGTGTCTCCTGTGAAGATGTCAATGAATGCATCACGGGCAGCCACAGCTGCCGGCTTGGAGAAT
CCTGCATCAACACAGTGGGCTCTTTCCGCTGCCAGCGGGACAGCAGCTGCGGGACTGGCTATGAGCTCACAGAGGACAATAGCTGCAAAG
ATATTGACGAGTGTGAGAGTGGTATTCATAACTGCCTCCCCGATTTTATCTGTCAGAATACTCTGGGATCCTTCCGCTGCCGACCCAAGC
TACAGTGCAAGAGTGGCTTTATACAAGATGCTCTAGGCAACTGTATTGATATCAATGAGTGTTTGAGTATCAGTGCCCCGTGCCCTATCG
GGCATACATGCATCAACACAGAGGGCTCCTACACGTGCCAGAAGAACGTGCCCAACTGTGGCCGTGGCTACCATCTCAACGAGGAGGGAA
CGCGCTGTGTTGATGTGGACGAGTGCGCGCCACCTGCTGAGCCCTGTGGGAAGGGACATCGCTGCGTGAACTCTCCCGGCAGTTTCCGCT
GCGAATGCAAGACGGGTTACTATTTTGACGGCATCAGCAGGATGTGTGTCGATGTCAACGAGTGCCAGCGCTACCCCGGGCGCCTGTGTG
GCCACAAGTGCGAGAACACGCTGGGCTCCTACCTCTGCAGCTGTTCCGTGGGCTTCCGGCTCTCTGTGGATGGCAGGTCATGTGAAGACA
TCAATGAGTGCAGCAGCAGCCCCTGTAGCCAGGAGTGTGCCAACGTCTACGGCTCCTACCAGTGTTACTGCCGGCGAGGCTACCAGCTCA
GCGATGTGGATGGAGTCACCTGTGAAGACATCGACGAGTGCGCCCTGCCCACCGGGGGCCACATCTGCTCCTACCGCTGCATCAACATCC
CTGGAAGCTTCCAGTGCAGCTGCCCCTCGTCTGGCTACAGGCTGGCCCCCAATGGCCGCAACTGCCAAGACATTGATGAGTGTGTGACTG
GCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTACCGCC
GCTCCGCAGCCACGCAGAAATCCAAGAAGGGAAGGCAGAACACCCCAGCGGGATCAAGTAAAGAGGACTGCAGGGTTCTTCCATGGAAGC
AGGGGTTGGAGGATACCCACCTTGATGCCTAGTGAGGAAGATGGACCTGGACAGACAGTCAGCTCCACACCTTGCGCTGAGCAGCTGTGA
TTGTGCCACGGGAGCATGAGCCCTTTTCCCCACGGCCCTTGCCACTGTCTCCTGGCCCTCTCTCTGATCATGCCAGGTTTGCACCAGCCT
CGAGTCTCCCATGTTGTAGTACATTCTCCAAGATGCAGCCCAGGAGCCTCTCTGAAGGACCAGTCTGGTTACGATGGTCTGAGCTTCCTT
AGAACCTTCCATGGTTGTCTTTTCCCAGCAGATGAAGCATAGCCTCCTTGGAATGGCATGGGAGGCCTGGCCTGATCTGGCCTCTGCCCA
CCCTTTGAGCTGCACCTGCCCCACCCCAGCTCATCCATGTGCTTGTACCCTGGCCCCACGGGGAGGCTTGCCCTTCCCTGAATCTGCCTT
CTTGTGGCTTTAGCATGTGCCATGCTGTCCCCCTGCAGACTGCCATTCTCCTTGCAGACTTGGCTCAGAAGTCACCTCCTCAGTGCAGTT
AGCCTGAGCTCCCCTGGCCCCAGGTGCCTCCATCAGAGCATTTACCCCATTGTGTTGTGGCTGTTCCTTAACGTCCCCACTAGCCAGGCT
CTTTGAGGGCAGGGATTGTGTCTGGTTAATTTCTGTATTCTCTGCAACTTTGCAATGTTTGGCTTGAAGAAGGAGCTCAGTAAACATCTG
AATAAACATGCAGGTTGATGG

>8370_8370_12_ATXN10-FBLN1_ATXN10_chr22_46088958_ENST00000381061_FBLN1_chr22_45914562_ENST00000442170_length(amino acids)=641AA_BP=65
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRNLDTIGVAVDLILLFRELRVEQESLLTVDADVLLEACCADGHRMATHQKDC
SLPYATESKECRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVF
QACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLG
ESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCP
IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL
CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN
IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGSSKEDCRVLPW
KQGLEDTHLDA

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for ATXN10-FBLN1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for ATXN10-FBLN1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for ATXN10-FBLN1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneATXN10C0687120Nephronophthisis1GENOMICS_ENGLAND
HgeneATXN10C1963674Spinocerebellar Ataxia 101CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneC1842422Synpolydactyly 23CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneC0014175Endometriosis1CTD_human
TgeneC0033578Prostatic Neoplasms1CTD_human
TgeneC0269102Endometrioma1CTD_human
TgeneC0376358Malignant neoplasm of prostate1CTD_human