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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SENP3-ABR (FusionGDB2 ID:HG26168TG29)

Fusion Gene Summary for SENP3-ABR

check button Fusion gene summary
Fusion gene informationFusion gene name: SENP3-ABR
Fusion gene ID: hg26168tg29
HgeneTgene
Gene symbol

SENP3

ABR

Gene ID

26168

29

Gene nameSUMO specific peptidase 3ABR activator of RhoGEF and GTPase
SynonymsSMT3IP1|SSP3|Ulp1MDB
Cytomap('SENP3')('ABR')

17p13.1

17p13.3

Type of geneprotein-codingprotein-coding
Descriptionsentrin-specific protease 3SUMO-1-specific protease 3SUMO1/sentrin/SMT3 specific peptidase 3sentrin/SUMO-specific protease 3active breakpoint cluster region-related proteinABR, RhoGEF and GTPase activating proteinactive BCR-related
Modification date2020031320200313
UniProtAcc.

Q12979

Ensembl transtripts involved in fusion geneENST00000578868, ENST00000321337, 
ENST00000429205, 
Fusion gene scores* DoF score6 X 5 X 5=15017 X 14 X 9=2142
# samples 621
** MAII scorelog2(6/150*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(21/2142*10)=-3.35049724708413
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SENP3 [Title/Abstract] AND ABR [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSENP3(7470322)-ABR(962107), # samples:3
Anticipated loss of major functional domain due to fusion event.SENP3-ABR seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
SENP3-ABR seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
SENP3-ABR seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
SENP3-ABR seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneABR

GO:0090630

activation of GTPase activity

7479768


check buttonFusion gene breakpoints across SENP3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ABR (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4COADTCGA-CM-6163-01ASENP3chr17

7470322

-ABRchr17

962107

-
ChimerDB4COADTCGA-CM-6163-01ASENP3chr17

7470322

+ABRchr17

962107

-


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Fusion Gene ORF analysis for SENP3-ABR

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000578868ENST00000302538SENP3chr17

7470322

+ABRchr17

962107

-
3UTR-3CDSENST00000578868ENST00000544583SENP3chr17

7470322

+ABRchr17

962107

-
3UTR-intronENST00000578868ENST00000291107SENP3chr17

7470322

+ABRchr17

962107

-
3UTR-intronENST00000578868ENST00000536794SENP3chr17

7470322

+ABRchr17

962107

-
3UTR-intronENST00000578868ENST00000543210SENP3chr17

7470322

+ABRchr17

962107

-
3UTR-intronENST00000578868ENST00000572441SENP3chr17

7470322

+ABRchr17

962107

-
3UTR-intronENST00000578868ENST00000573895SENP3chr17

7470322

+ABRchr17

962107

-
3UTR-intronENST00000578868ENST00000574437SENP3chr17

7470322

+ABRchr17

962107

-
5CDS-intronENST00000321337ENST00000291107SENP3chr17

7470322

+ABRchr17

962107

-
5CDS-intronENST00000321337ENST00000536794SENP3chr17

7470322

+ABRchr17

962107

-
5CDS-intronENST00000321337ENST00000543210SENP3chr17

7470322

+ABRchr17

962107

-
5CDS-intronENST00000321337ENST00000572441SENP3chr17

7470322

+ABRchr17

962107

-
5CDS-intronENST00000321337ENST00000573895SENP3chr17

7470322

+ABRchr17

962107

-
5CDS-intronENST00000321337ENST00000574437SENP3chr17

7470322

+ABRchr17

962107

-
5CDS-intronENST00000429205ENST00000291107SENP3chr17

7470322

+ABRchr17

962107

-
5CDS-intronENST00000429205ENST00000536794SENP3chr17

7470322

+ABRchr17

962107

-
5CDS-intronENST00000429205ENST00000543210SENP3chr17

7470322

+ABRchr17

962107

-
5CDS-intronENST00000429205ENST00000572441SENP3chr17

7470322

+ABRchr17

962107

-
5CDS-intronENST00000429205ENST00000573895SENP3chr17

7470322

+ABRchr17

962107

-
5CDS-intronENST00000429205ENST00000574437SENP3chr17

7470322

+ABRchr17

962107

-
In-frameENST00000321337ENST00000302538SENP3chr17

7470322

+ABRchr17

962107

-
In-frameENST00000321337ENST00000544583SENP3chr17

7470322

+ABRchr17

962107

-
In-frameENST00000429205ENST00000302538SENP3chr17

7470322

+ABRchr17

962107

-
In-frameENST00000429205ENST00000544583SENP3chr17

7470322

+ABRchr17

962107

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000321337SENP3chr177470322+ENST00000302538ABRchr17962107-561816583203055911
ENST00000321337SENP3chr177470322+ENST00000544583ABRchr17962107-560916583203055911
ENST00000429205SENP3chr177470322+ENST00000302538ABRchr17962107-53501390492787912
ENST00000429205SENP3chr177470322+ENST00000544583ABRchr17962107-53411390492787912

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000321337ENST00000302538SENP3chr177470322+ABRchr17962107-0.0017778940.99822205
ENST00000321337ENST00000544583SENP3chr177470322+ABRchr17962107-0.0017645010.99823546
ENST00000429205ENST00000302538SENP3chr177470322+ABRchr17962107-0.0015901940.99840975
ENST00000429205ENST00000544583SENP3chr177470322+ABRchr17962107-0.0015765110.99842346

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Fusion Genomic Features for SENP3-ABR


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for SENP3-ABR


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:7470322/chr17:962107)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ABR

Q12979

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. The C-terminus is a GTPase-activating protein domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form (PubMed:7479768, PubMed:17116687). The central Dbl homology (DH) domain functions as guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1. Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound to the GTP-bound form (PubMed:7479768). Functions as an important negative regulator of neuronal RAC1 activity (By similarity). Regulates macrophage functions such as CSF-1 directed motility and phagocytosis through the modulation of RAC1 activity (By similarity). {ECO:0000250|UniProtKB:Q5SSL4, ECO:0000269|PubMed:17116687, ECO:0000269|PubMed:7479768}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSENP3chr17:7470322chr17:962107ENST00000429205+81313_68447582.6666666666666Compositional biasNote=Pro-rich
HgeneSENP3chr17:7470322chr17:962107ENST00000429205+813192_195447582.6666666666666Compositional biasNote=Poly-Pro
HgeneSENP3chr17:7470322chr17:962107ENST00000429205+81376_92447582.6666666666666Compositional biasNote=Glu-rich
HgeneSENP3chr17:7470322chr17:962107ENST00000429205+813125_128447582.6666666666666MotifNuclear localization signal
HgeneSENP3chr17:7470322chr17:962107ENST00000429205+813153_159447582.6666666666666MotifNuclear localization signal
TgeneABRchr17:7470322chr17:962107ENST00000291107822417_420357823.0Compositional biasNote=Poly-Leu
TgeneABRchr17:7470322chr17:962107ENST00000302538923417_420394860.0Compositional biasNote=Poly-Leu
TgeneABRchr17:7470322chr17:962107ENST0000054321008417_4200311.0Compositional biasNote=Poly-Leu
TgeneABRchr17:7470322chr17:962107ENST00000544583923417_420348814.0Compositional biasNote=Poly-Leu
TgeneABRchr17:7470322chr17:962107ENST00000574437822417_420348814.0Compositional biasNote=Poly-Leu
TgeneABRchr17:7470322chr17:962107ENST00000291107822484_613357823.0DomainC2
TgeneABRchr17:7470322chr17:962107ENST00000291107822647_845357823.0DomainRho-GAP
TgeneABRchr17:7470322chr17:962107ENST00000302538923484_613394860.0DomainC2
TgeneABRchr17:7470322chr17:962107ENST00000302538923647_845394860.0DomainRho-GAP
TgeneABRchr17:7470322chr17:962107ENST0000054321008301_4590311.0DomainPH
TgeneABRchr17:7470322chr17:962107ENST0000054321008484_6130311.0DomainC2
TgeneABRchr17:7470322chr17:962107ENST0000054321008647_8450311.0DomainRho-GAP
TgeneABRchr17:7470322chr17:962107ENST000005432100891_2840311.0DomainDH
TgeneABRchr17:7470322chr17:962107ENST00000544583923484_613348814.0DomainC2
TgeneABRchr17:7470322chr17:962107ENST00000544583923647_845348814.0DomainRho-GAP
TgeneABRchr17:7470322chr17:962107ENST00000574437822484_613348814.0DomainC2
TgeneABRchr17:7470322chr17:962107ENST00000574437822647_845348814.0DomainRho-GAP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSENP3chr17:7470322chr17:962107ENST00000429205+813386_543447582.6666666666666RegionNote=Protease
TgeneABRchr17:7470322chr17:962107ENST00000291107822301_459357823.0DomainPH
TgeneABRchr17:7470322chr17:962107ENST0000029110782291_284357823.0DomainDH
TgeneABRchr17:7470322chr17:962107ENST00000302538923301_459394860.0DomainPH
TgeneABRchr17:7470322chr17:962107ENST0000030253892391_284394860.0DomainDH
TgeneABRchr17:7470322chr17:962107ENST00000544583923301_459348814.0DomainPH
TgeneABRchr17:7470322chr17:962107ENST0000054458392391_284348814.0DomainDH
TgeneABRchr17:7470322chr17:962107ENST00000574437822301_459348814.0DomainPH
TgeneABRchr17:7470322chr17:962107ENST0000057443782291_284348814.0DomainDH


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Fusion Gene Sequence for SENP3-ABR


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>80385_80385_1_SENP3-ABR_SENP3_chr17_7470322_ENST00000321337_ABR_chr17_962107_ENST00000302538_length(transcript)=5618nt_BP=1658nt
CCCGGGGCTCGCGGGAGGGGAAGGAGGAGGGGGGGAGGAGTGGCGGCGGCGGCGGTGGCGCTGGTGGCGGCGGTGGCGGAGGTGGAGGTG
GAGGTGGAAGCTGAAGCTGAAGCAGAGCCAGAGGCGGCGCGGCGGGGTGCTCGGCGGCGCGGCACGCGGCCCAGAAGCGTTGGAATCCTG
AATTGAGACGGCTGCGCCTAAAGACAGCAGGAGTGGCGGGGCCGCCGCCGTCGCCGGAGAGATGAGCCGGGAAGCTTGAGGCCGGAGACG
CCCGCCTTCGGGCCCGTCCGCCCGGCTTCCCCGCTCCCGGGTACTGGAAGATGAAAGAGACTATACAAGGGACCGGGTCCTGGGGGCCTG
AGCCTCCTGGACCCGGCATACCCCCAGCTTACTCAAGTCCCAGGCGGGAGCGTCTTCGTTGGCCCCCACCTCCCAAACCCCGACTCAAGT
CAGGTGGAGGGTTTGGGCCAGATCCTGGGTCAGGGACCACAGTGCCAGCCAGACGCCTCCCTGTCCCCCGACCCTCTTTTGATGCCTCAG
CAAGTGAAGAGGAGGAAGAAGAGGAGGAGGAGGAGGATGAAGATGAAGAGGAGGAAGTGGCAGCTTGGAGGCTGCCCCCAAGATGGAGTC
AGCTGGGAACCTCCCAGCGGCCCCGCCCTTCCCGCCCCACTCATCGAAAAACCTGCTCACAGCGCCGCCGCCGAGCCATGAGAGCCTTCC
GGATGCTGCTCTACTCAAAAAGCACCTCGCTGACATTCCACTGGAAGCTTTGGGGGCGCCACCGGGGCCGGCGGCGGGGCCTCGCACACC
CCAAGAACCATCTTTCACCCCAGCAAGGGGGTGCGACGCCACAGGTGCCATCCCCCTGTTGTCGTTTTGACTCCCCCCGGGGGCCACCTC
CACCCCGGCTGGGTCTGCTAGGTGCTCTCATGGCTGAGGATGGGGTGAGAGGGTCTCCACCAGTGCCCTCTGGGCCCCCCATGGAGGAAG
ATGGACTCAGGTGGACTCCAAAGTCTCCTCTGGACCCTGACTCGGGCCTCCTTTCATGTACTCTGCCCAACGGTTTTGGGGGACAATCTG
GGCCAGAAGGGGAGCGCAGCTTGGCACCCCCTGATGCCAGCATCCTCATCAGCAATGTGTGCAGCATCGGGGACCATGTGGCCCAGGAGC
TTTTTCAGGGCTCAGATTTGGGCATGGCAGAAGAGGCAGAGAGGCCTGGGGAGAAAGCCGGCCAGCACAGCCCCCTGCGAGAGGAGCATG
TGACCTGCGTACAGAGCATCTTGGACGAATTCCTTCAAACGTATGGCAGCCTCATACCCCTCAGCACTGATGAGGTAGTAGAGAAGCTGG
AGGACATTTTCCAGCAGGAGTTTTCCACCCCTTCCAGGAAGGGCCTGGTGTTGCAGCTGATCCAGTCTTACCAGCGGATGCCAGGCAATG
CCATGGTGAGGGGCTTCCGAGTGGCTTATAAGCGGCACGTGCTGACCATGGATGACTTGGGGACCTTGTATGGACAGAACTGGCTCAATG
ACCAGGTGATGAACATGTATGGAGACCTGGTCATGGACACAGTCCCTGAAAAGGTGCATTTCTTCAATAGTTTCTTCTATGATAAACTCC
GTACCGGTTATGATGGGGTGAAAAGGTGGACCAAAAACAAAGCCAACAAAGGCCAGAGCCGGGCCATCGAGCGCCTGAAGAAGAAGATGT
TTGAGAATGAGTTCCTGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAATCGGAATGGAAAGAGTTACCTGTTCCTACTGT
CCTCGGACTACGAGAGGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGATCTCCAGGCCTTTGTCCTGAGCTCAGTGGAGC
TCCAGGTGCTCACAGGATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACCAGCAATAAAGACGACGATGAGTCTCCAGGAC
TCTATGGCTTCCTTCATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAACCTGTACTGTACCCTGGAGGTGGATTCCTTCG
GCTATTTTGTCAGCAAAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGGGATGAGGAGTTTGAGATCGAGCTGGAGGGCT
CCCAGTCCCTGAGGATCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAGGACAACAATGAGATCGTGGACAAGATCATGG
GCAAAGGACAGATCCAGCTGGACCCACAAACCGTGGAGACCAAGAACTGGCACACGGACGTGATTGAGATGAACGGGATCAAAGTGGAAT
TTTCCATGAAATTCACCAGCCGAGATATGAGCCTGAAGAGGACCCCGTCCAAAAAGCAGACCGGCGTCTTCGGTGTGAAGATCAGCGTGG
TGACGAAGCGGGAGCGCTCCAAGGTGCCCTACATCGTCCGGCAGTGTGTGGAGGAGGTGGAGAAGAGGGGTATCGAGGAGGTTGGCATCT
ACAGGATATCGGGCGTGGCCACGGACATCCAGGCGCTCAAGGCCGTCTTCGATGCCAATAACAAGGACATCCTGCTGATGCTGAGTGACA
TGGACATCAACGCCATCGCCGGGACGCTCAAGCTGTACTTCCGGGAACTGCCCGAGCCGCTCCTCACGGACCGACTCTACCCAGCCTTCA
TGGAGGGCATCGCCCTGTCAGACCCTGCTGCCAAGGAAAACTGCATGATGCACCTGCTCCGCTCCCTGCCCGACCCCAACCTCATCACCT
TCCTCTTCCTGCTGGAACACTTGAAAAGGGTTGCCGAGAAGGAGCCCATCAACAAAATGTCACTTCACAACCTGGCTACCGTGTTTGGAC
CCACGTTACTGAGACCCTCAGAAGTGGAGAGCAAAGCACACCTCACCTCGGCTGCGGACATCTGGTCCCATGACGTCATGGCGCAGGTCC
AGGTCCTCCTCTACTACCTGCAGCACCCCCCCATTTCCTTCGCAGAACTCAAGCGGAACACACTGTACTTCTCCACCGACGTGTAGCCCG
AGGCAGGGTGGCTGCGGGCGGGTGGTGGAACCAGCCCCTCCAGCCTGGGGTCCAACTCAGACTTGAAAGACTGCAATAGAAAACTCCCAA
ACCCAGCACTCCAGACTCGAGGGAAGCCAGCTTCCAAGAACTGGAATGCGTACGTCTTTTGTGCCACCTTGTACAAAGCCGGCTGCCCAG
CCCCAGCCTCACCACCGCATCCCACCTCCTGCCCTCCATACCTCTAGTTGTGTCTGATGCTCCGTGCTGTTCGGGAATTGTTTTATGTAC
ACTTGTCAGGCAGAAAAGGTAGTGACCGGCCCGGCGTGGGCACACAGACAGCCCGCTTTGTTCTTTCATTTCCTCCAGCACTTTCTTTCC
GCCTGAGTCCAGCCCAAGGCCTTTTATTTTGCGCTGTGTAACTGCTGCCAGCTTCTCTCTTGGCCCTGCTCCCAGATGGCGGTCTCCTGG
CAGCCTCCCCTCAGTCTTCCTCCACCCGCTCTTCCTTCCCAGCCTGCCTGCATGCATGTGCACCCTTGGTCTTCGCTCCATCGCCTTGAA
AGCTCTGAAGAGGCCCTGGGTTGCCGCGGCAGCAGTGGTCTGTTTGATGCTGCCGTTTGCCGCTGCCGGCCCCTCCTCAGACTCCGCCTT
TGGGAGCACACCTGCTTTGCCTTGCTGCCTGTGCAAATGTTGGACAAGCAGACACACTCACACTCGTCCCCAGCTTAGCACAGAGCTGGA
GCGCCCATTTCTGGAATTTTCCGTTTGGGAATCTCCACTTCTGGGGTTTACCTGTTCGGCCTCCTGTCTATCAGTGAGGCATCTCTGACT
GTTTCTTCTACTGCTTTTCAGTTCCCTTCCCTGCTGTTCTATTTCCTTTGAGTGTAAAGACTCACAGGTGACCTGCTATCGAGATAGCCA
GAGGGTCAGGAGAGAATGGGGGAGGAGGCGGTCAGGCTGCTGAGGAAACACCACAGGCTGAACGGGGGAGGAATGCACATGCCACGCTGG
GTGTCCCGGGTCGCGGGGAGGCAGCTCAGCTCTTAGGAGCAAGTTGTGGGGGCTTTTCAAGAGGGGCCAGGCTTCCTGGAGGGTGACTGA
TGTGGCCGAAGCAGGTGTCCAGGCAGGTAGGCTGCAGCCAGGAGCTCCCTGGCACCGCAGGACCTCGTGGTACTCTTGCCTTAGATTTTA
CACACACTCCACAGCCAAGCACTGCCACGGTCCTCCAGGACCTGGGAAGCAAAGGCACAGGCCCACGGTGGCCAGCCATTGTGGTGCCGC
CCCAGCTTCTGGATACAGCCTTTTGGGTAAACACTGGGAACTCCAGAAGTTGTGGGGAGAGTGGGGAATCAGACAGCCGCCTCTAGGGGC
TGGGTTCTGCTGGGGCCTCCTTGTTGGTGCTGTAGGCACCCGCCAGGGAGCAGGGACCCGACTTGCAGACGCATTGCCCGGTACTAGGAA
GGAGTGAGGTGTGTTCCCACCGTACACTTCCCACACGAGCTGCGGCTGCCAGCCTCGGGCCATCAGCCTAGGAGAGCAGATGCAGCTCCA
GGGGCTCGACTTATAGCCAGTTACAGCTCCCCGGCTCTTCTGTGTGGCAGAGCGTCGTTTCCGGGCCCTCAGGGCTGGGGAGCTCAGTTC
CCATTGCTTGTGCTCAGGGCTGAGTCTTAAAGAAGGGTTTGCCGGCCCTAACGCTGCAGCGCGTGCGCGGTGAGAGGCCCTTTTTGAGCC
TGTTTACTCCTGTGGCCTTGGGCAGAACAGTAAATACTCTGTGCACGGAGGAAAGACATGCCCAAGAGGAAGGAAGTACTGACCATCGGC
TGCCTGTGAGCAGCTTAGCAAGGAGCCCTTGCTCCCTGGGAAAGGCGGTGAACTTGAGTCTAAAGATGCAGTGCCTGGCCCTTCCTAAGG
TCCCTGCCTGGCATCCGAGTGTCGGTGTGTGGCACAGAAGGCTCCTGCTTGCTTCCAAAGTGATGGACAGGAAGGGGCAGAGTGAGTCAC
GGCCCAGACTGGGCACCTTCGCGTCTCAGCCTCAGGGAGCCCCACAGCCCCAAGCTCGCTGAGGCAACGTGAGAACAGGCTATGGGAAGG
CTGCAAAGGCTGAGAAATGCAAAGGCTCATATTTATAAATCCCACCCCCAGAGTGGGGAGGGTCAGGTGCCAGACCTGGACTAAACTGCA
CCAAGGAAACACCCAGCAGGGTCTCCTGTGAGCCGGGGACCATGCAGCCCGAAACCTCCAGTCACTGCGCCCGGCAGGAGTCAGGAGCCA
GGGACTGTGCAGCCTGGAACCTCCAGTCACTGTGCCCAGCAGGGTGGGCTGTGCCCAGCAGGAGTCAGGCTAAGAAACGCCAGGTCTGCC
TGTTCTTGCTGGGCAATGGCTGATGGCTGCCAGTTTCTGCTGATACACAGGTAGGATGGGACCCTTCATGAATATCTGACTTTAATAAGT
TGGTAAGGATATATTTTTTTGTCTATGTTCTGTTTCAACTTATGTAGATTATTATAAATTGATGTAAACCACGTGAGAGGAAAATGTTAA

>80385_80385_1_SENP3-ABR_SENP3_chr17_7470322_ENST00000321337_ABR_chr17_962107_ENST00000302538_length(amino acids)=911AA_BP=446
MKETIQGTGSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPARRLPVPRPSFDASASEEEEEEEEEEDEDEE
EEVAAWRLPPRWSQLGTSQRPRPSRPTHRKTCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRGLAHPKNHLSPQQGGATPQVP
SPCCRFDSPRGPPPPRLGLLGALMAEDGVRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGQSGPEGERSLAPPDASILI
SNVCSIGDHVAQELFQGSDLGMAEEAERPGEKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKGLV
LQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEKVHFFNSFFYDKLRTGYDGVKRWTKNKANK
GQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHNI
PVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTK
VNKDNNEIVDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQCV
EEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMM
HLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFAEL

--------------------------------------------------------------
>80385_80385_2_SENP3-ABR_SENP3_chr17_7470322_ENST00000321337_ABR_chr17_962107_ENST00000544583_length(transcript)=5609nt_BP=1658nt
CCCGGGGCTCGCGGGAGGGGAAGGAGGAGGGGGGGAGGAGTGGCGGCGGCGGCGGTGGCGCTGGTGGCGGCGGTGGCGGAGGTGGAGGTG
GAGGTGGAAGCTGAAGCTGAAGCAGAGCCAGAGGCGGCGCGGCGGGGTGCTCGGCGGCGCGGCACGCGGCCCAGAAGCGTTGGAATCCTG
AATTGAGACGGCTGCGCCTAAAGACAGCAGGAGTGGCGGGGCCGCCGCCGTCGCCGGAGAGATGAGCCGGGAAGCTTGAGGCCGGAGACG
CCCGCCTTCGGGCCCGTCCGCCCGGCTTCCCCGCTCCCGGGTACTGGAAGATGAAAGAGACTATACAAGGGACCGGGTCCTGGGGGCCTG
AGCCTCCTGGACCCGGCATACCCCCAGCTTACTCAAGTCCCAGGCGGGAGCGTCTTCGTTGGCCCCCACCTCCCAAACCCCGACTCAAGT
CAGGTGGAGGGTTTGGGCCAGATCCTGGGTCAGGGACCACAGTGCCAGCCAGACGCCTCCCTGTCCCCCGACCCTCTTTTGATGCCTCAG
CAAGTGAAGAGGAGGAAGAAGAGGAGGAGGAGGAGGATGAAGATGAAGAGGAGGAAGTGGCAGCTTGGAGGCTGCCCCCAAGATGGAGTC
AGCTGGGAACCTCCCAGCGGCCCCGCCCTTCCCGCCCCACTCATCGAAAAACCTGCTCACAGCGCCGCCGCCGAGCCATGAGAGCCTTCC
GGATGCTGCTCTACTCAAAAAGCACCTCGCTGACATTCCACTGGAAGCTTTGGGGGCGCCACCGGGGCCGGCGGCGGGGCCTCGCACACC
CCAAGAACCATCTTTCACCCCAGCAAGGGGGTGCGACGCCACAGGTGCCATCCCCCTGTTGTCGTTTTGACTCCCCCCGGGGGCCACCTC
CACCCCGGCTGGGTCTGCTAGGTGCTCTCATGGCTGAGGATGGGGTGAGAGGGTCTCCACCAGTGCCCTCTGGGCCCCCCATGGAGGAAG
ATGGACTCAGGTGGACTCCAAAGTCTCCTCTGGACCCTGACTCGGGCCTCCTTTCATGTACTCTGCCCAACGGTTTTGGGGGACAATCTG
GGCCAGAAGGGGAGCGCAGCTTGGCACCCCCTGATGCCAGCATCCTCATCAGCAATGTGTGCAGCATCGGGGACCATGTGGCCCAGGAGC
TTTTTCAGGGCTCAGATTTGGGCATGGCAGAAGAGGCAGAGAGGCCTGGGGAGAAAGCCGGCCAGCACAGCCCCCTGCGAGAGGAGCATG
TGACCTGCGTACAGAGCATCTTGGACGAATTCCTTCAAACGTATGGCAGCCTCATACCCCTCAGCACTGATGAGGTAGTAGAGAAGCTGG
AGGACATTTTCCAGCAGGAGTTTTCCACCCCTTCCAGGAAGGGCCTGGTGTTGCAGCTGATCCAGTCTTACCAGCGGATGCCAGGCAATG
CCATGGTGAGGGGCTTCCGAGTGGCTTATAAGCGGCACGTGCTGACCATGGATGACTTGGGGACCTTGTATGGACAGAACTGGCTCAATG
ACCAGGTGATGAACATGTATGGAGACCTGGTCATGGACACAGTCCCTGAAAAGGTGCATTTCTTCAATAGTTTCTTCTATGATAAACTCC
GTACCGGTTATGATGGGGTGAAAAGGTGGACCAAAAACAAAGCCAACAAAGGCCAGAGCCGGGCCATCGAGCGCCTGAAGAAGAAGATGT
TTGAGAATGAGTTCCTGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAATCGGAATGGAAAGAGTTACCTGTTCCTACTGT
CCTCGGACTACGAGAGGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGATCTCCAGGCCTTTGTCCTGAGCTCAGTGGAGC
TCCAGGTGCTCACAGGATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACCAGCAATAAAGACGACGATGAGTCTCCAGGAC
TCTATGGCTTCCTTCATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAACCTGTACTGTACCCTGGAGGTGGATTCCTTCG
GCTATTTTGTCAGCAAAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGGGATGAGGAGTTTGAGATCGAGCTGGAGGGCT
CCCAGTCCCTGAGGATCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAGGACAACAATGAGATCGTGGACAAGATCATGG
GCAAAGGACAGATCCAGCTGGACCCACAAACCGTGGAGACCAAGAACTGGCACACGGACGTGATTGAGATGAACGGGATCAAAGTGGAAT
TTTCCATGAAATTCACCAGCCGAGATATGAGCCTGAAGAGGACCCCGTCCAAAAAGCAGACCGGCGTCTTCGGTGTGAAGATCAGCGTGG
TGACGAAGCGGGAGCGCTCCAAGGTGCCCTACATCGTCCGGCAGTGTGTGGAGGAGGTGGAGAAGAGGGGTATCGAGGAGGTTGGCATCT
ACAGGATATCGGGCGTGGCCACGGACATCCAGGCGCTCAAGGCCGTCTTCGATGCCAATAACAAGGACATCCTGCTGATGCTGAGTGACA
TGGACATCAACGCCATCGCCGGGACGCTCAAGCTGTACTTCCGGGAACTGCCCGAGCCGCTCCTCACGGACCGACTCTACCCAGCCTTCA
TGGAGGGCATCGCCCTGTCAGACCCTGCTGCCAAGGAAAACTGCATGATGCACCTGCTCCGCTCCCTGCCCGACCCCAACCTCATCACCT
TCCTCTTCCTGCTGGAACACTTGAAAAGGGTTGCCGAGAAGGAGCCCATCAACAAAATGTCACTTCACAACCTGGCTACCGTGTTTGGAC
CCACGTTACTGAGACCCTCAGAAGTGGAGAGCAAAGCACACCTCACCTCGGCTGCGGACATCTGGTCCCATGACGTCATGGCGCAGGTCC
AGGTCCTCCTCTACTACCTGCAGCACCCCCCCATTTCCTTCGCAGAACTCAAGCGGAACACACTGTACTTCTCCACCGACGTGTAGCCCG
AGGCAGGGTGGCTGCGGGCGGGTGGTGGAACCAGCCCCTCCAGCCTGGGGTCCAACTCAGACTTGAAAGACTGCAATAGAAAACTCCCAA
ACCCAGCACTCCAGACTCGAGGGAAGCCAGCTTCCAAGAACTGGAATGCGTACGTCTTTTGTGCCACCTTGTACAAAGCCGGCTGCCCAG
CCCCAGCCTCACCACCGCATCCCACCTCCTGCCCTCCATACCTCTAGTTGTGTCTGATGCTCCGTGCTGTTCGGGAATTGTTTTATGTAC
ACTTGTCAGGCAGAAAAGGTAGTGACCGGCCCGGCGTGGGCACACAGACAGCCCGCTTTGTTCTTTCATTTCCTCCAGCACTTTCTTTCC
GCCTGAGTCCAGCCCAAGGCCTTTTATTTTGCGCTGTGTAACTGCTGCCAGCTTCTCTCTTGGCCCTGCTCCCAGATGGCGGTCTCCTGG
CAGCCTCCCCTCAGTCTTCCTCCACCCGCTCTTCCTTCCCAGCCTGCCTGCATGCATGTGCACCCTTGGTCTTCGCTCCATCGCCTTGAA
AGCTCTGAAGAGGCCCTGGGTTGCCGCGGCAGCAGTGGTCTGTTTGATGCTGCCGTTTGCCGCTGCCGGCCCCTCCTCAGACTCCGCCTT
TGGGAGCACACCTGCTTTGCCTTGCTGCCTGTGCAAATGTTGGACAAGCAGACACACTCACACTCGTCCCCAGCTTAGCACAGAGCTGGA
GCGCCCATTTCTGGAATTTTCCGTTTGGGAATCTCCACTTCTGGGGTTTACCTGTTCGGCCTCCTGTCTATCAGTGAGGCATCTCTGACT
GTTTCTTCTACTGCTTTTCAGTTCCCTTCCCTGCTGTTCTATTTCCTTTGAGTGTAAAGACTCACAGGTGACCTGCTATCGAGATAGCCA
GAGGGTCAGGAGAGAATGGGGGAGGAGGCGGTCAGGCTGCTGAGGAAACACCACAGGCTGAACGGGGGAGGAATGCACATGCCACGCTGG
GTGTCCCGGGTCGCGGGGAGGCAGCTCAGCTCTTAGGAGCAAGTTGTGGGGGCTTTTCAAGAGGGGCCAGGCTTCCTGGAGGGTGACTGA
TGTGGCCGAAGCAGGTGTCCAGGCAGGTAGGCTGCAGCCAGGAGCTCCCTGGCACCGCAGGACCTCGTGGTACTCTTGCCTTAGATTTTA
CACACACTCCACAGCCAAGCACTGCCACGGTCCTCCAGGACCTGGGAAGCAAAGGCACAGGCCCACGGTGGCCAGCCATTGTGGTGCCGC
CCCAGCTTCTGGATACAGCCTTTTGGGTAAACACTGGGAACTCCAGAAGTTGTGGGGAGAGTGGGGAATCAGACAGCCGCCTCTAGGGGC
TGGGTTCTGCTGGGGCCTCCTTGTTGGTGCTGTAGGCACCCGCCAGGGAGCAGGGACCCGACTTGCAGACGCATTGCCCGGTACTAGGAA
GGAGTGAGGTGTGTTCCCACCGTACACTTCCCACACGAGCTGCGGCTGCCAGCCTCGGGCCATCAGCCTAGGAGAGCAGATGCAGCTCCA
GGGGCTCGACTTATAGCCAGTTACAGCTCCCCGGCTCTTCTGTGTGGCAGAGCGTCGTTTCCGGGCCCTCAGGGCTGGGGAGCTCAGTTC
CCATTGCTTGTGCTCAGGGCTGAGTCTTAAAGAAGGGTTTGCCGGCCCTAACGCTGCAGCGCGTGCGCGGTGAGAGGCCCTTTTTGAGCC
TGTTTACTCCTGTGGCCTTGGGCAGAACAGTAAATACTCTGTGCACGGAGGAAAGACATGCCCAAGAGGAAGGAAGTACTGACCATCGGC
TGCCTGTGAGCAGCTTAGCAAGGAGCCCTTGCTCCCTGGGAAAGGCGGTGAACTTGAGTCTAAAGATGCAGTGCCTGGCCCTTCCTAAGG
TCCCTGCCTGGCATCCGAGTGTCGGTGTGTGGCACAGAAGGCTCCTGCTTGCTTCCAAAGTGATGGACAGGAAGGGGCAGAGTGAGTCAC
GGCCCAGACTGGGCACCTTCGCGTCTCAGCCTCAGGGAGCCCCACAGCCCCAAGCTCGCTGAGGCAACGTGAGAACAGGCTATGGGAAGG
CTGCAAAGGCTGAGAAATGCAAAGGCTCATATTTATAAATCCCACCCCCAGAGTGGGGAGGGTCAGGTGCCAGACCTGGACTAAACTGCA
CCAAGGAAACACCCAGCAGGGTCTCCTGTGAGCCGGGGACCATGCAGCCCGAAACCTCCAGTCACTGCGCCCGGCAGGAGTCAGGAGCCA
GGGACTGTGCAGCCTGGAACCTCCAGTCACTGTGCCCAGCAGGGTGGGCTGTGCCCAGCAGGAGTCAGGCTAAGAAACGCCAGGTCTGCC
TGTTCTTGCTGGGCAATGGCTGATGGCTGCCAGTTTCTGCTGATACACAGGTAGGATGGGACCCTTCATGAATATCTGACTTTAATAAGT
TGGTAAGGATATATTTTTTTGTCTATGTTCTGTTTCAACTTATGTAGATTATTATAAATTGATGTAAACCACGTGAGAGGAAAATGTTAA

>80385_80385_2_SENP3-ABR_SENP3_chr17_7470322_ENST00000321337_ABR_chr17_962107_ENST00000544583_length(amino acids)=911AA_BP=446
MKETIQGTGSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPARRLPVPRPSFDASASEEEEEEEEEEDEDEE
EEVAAWRLPPRWSQLGTSQRPRPSRPTHRKTCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRGLAHPKNHLSPQQGGATPQVP
SPCCRFDSPRGPPPPRLGLLGALMAEDGVRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGQSGPEGERSLAPPDASILI
SNVCSIGDHVAQELFQGSDLGMAEEAERPGEKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKGLV
LQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEKVHFFNSFFYDKLRTGYDGVKRWTKNKANK
GQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHNI
PVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTK
VNKDNNEIVDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQCV
EEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMM
HLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFAEL

--------------------------------------------------------------
>80385_80385_3_SENP3-ABR_SENP3_chr17_7470322_ENST00000429205_ABR_chr17_962107_ENST00000302538_length(transcript)=5350nt_BP=1390nt
CCGCCTTCGGGCCCGTCCGCCCGGCTTCCCCGCTCCCGGGTACTGGAAGATGAAAGAGACTATACAAGGGACCGGGTCCTGGGGGCCTGA
GCCTCCTGGACCCGGCATACCCCCAGCTTACTCAAGTCCCAGGCGGGAGCGTCTTCGTTGGCCCCCACCTCCCAAACCCCGACTCAAGTC
AGGTGGAGGGTTTGGGCCAGATCCTGGGTCAGGGACCACAGTGCCAGCCAGACGCCTCCCTGTCCCCCGACCCTCTTTTGATGCCTCAGC
AAGTGAAGAGGAGGAAGAAGAGGAGGAGGAGGAGGATGAAGATGAAGAGGAGGAAGTGGCAGCTTGGAGGCTGCCCCCAAGATGGAGTCA
GCTGGGAACCTCCCAGCGGCCCCGCCCTTCCCGCCCCACTCATCGAAAAACCTGCTCACAGCGCCGCCGCCGAGCCATGAGAGCCTTCCG
GATGCTGCTCTACTCAAAAAGCACCTCGCTGACATTCCACTGGAAGCTTTGGGGGCGCCACCGGGGCCGGCGGCGGGGCCTCGCACACCC
CAAGAACCATCTTTCACCCCAGCAAGGGGGTGCGACGCCACAGGTGCCATCCCCCTGTTGTCGTTTTGACTCCCCCCGGGGGCCACCTCC
ACCCCGGCTGGGTCTGCTAGGTGCTCTCATGGCTGAGGATGGGGTGAGAGGGTCTCCACCAGTGCCCTCTGGGCCCCCCATGGAGGAAGA
TGGACTCAGGTGGACTCCAAAGTCTCCTCTGGACCCTGACTCGGGCCTCCTTTCATGTACTCTGCCCAACGGTTTTGGGGGACAATCTGG
GCCAGAAGGGGAGCGCAGCTTGGCACCCCCTGATGCCAGCATCCTCATCAGCAATGTGTGCAGCATCGGGGACCATGTGGCCCAGGAGCT
TTTTCAGGGCTCAGATTTGGGCATGGCAGAAGAGGCAGAGAGGCCTGGGGAGAAAGCCGGCCAGCACAGCCCCCTGCGAGAGGAGCATGT
GACCTGCGTACAGAGCATCTTGGACGAATTCCTTCAAACGTATGGCAGCCTCATACCCCTCAGCACTGATGAGGTAGTAGAGAAGCTGGA
GGACATTTTCCAGCAGGAGTTTTCCACCCCTTCCAGGAAGGGCCTGGTGTTGCAGCTGATCCAGTCTTACCAGCGGATGCCAGGCAATGC
CATGGTGAGGGGCTTCCGAGTGGCTTATAAGCGGCACGTGCTGACCATGGATGACTTGGGGACCTTGTATGGACAGAACTGGCTCAATGA
CCAGGTGATGAACATGTATGGAGACCTGGTCATGGACACAGTCCCTGAAAAGGTGCATTTCTTCAATAGTTTCTTCTATGATAAACTCCG
TACCAAGGGTTATGATGGGGTGAAAAGGTGGACCAAAAACAAAGCCAACAAAGGCCAGAGCCGGGCCATCGAGCGCCTGAAGAAGAAGAT
GTTTGAGAATGAGTTCCTGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAATCGGAATGGAAAGAGTTACCTGTTCCTACT
GTCCTCGGACTACGAGAGGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGATCTCCAGGCCTTTGTCCTGAGCTCAGTGGA
GCTCCAGGTGCTCACAGGATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACCAGCAATAAAGACGACGATGAGTCTCCAGG
ACTCTATGGCTTCCTTCATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAACCTGTACTGTACCCTGGAGGTGGATTCCTT
CGGCTATTTTGTCAGCAAAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGGGATGAGGAGTTTGAGATCGAGCTGGAGGG
CTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAGGACAACAATGAGATCGTGGACAAGATCAT
GGGCAAAGGACAGATCCAGCTGGACCCACAAACCGTGGAGACCAAGAACTGGCACACGGACGTGATTGAGATGAACGGGATCAAAGTGGA
ATTTTCCATGAAATTCACCAGCCGAGATATGAGCCTGAAGAGGACCCCGTCCAAAAAGCAGACCGGCGTCTTCGGTGTGAAGATCAGCGT
GGTGACGAAGCGGGAGCGCTCCAAGGTGCCCTACATCGTCCGGCAGTGTGTGGAGGAGGTGGAGAAGAGGGGTATCGAGGAGGTTGGCAT
CTACAGGATATCGGGCGTGGCCACGGACATCCAGGCGCTCAAGGCCGTCTTCGATGCCAATAACAAGGACATCCTGCTGATGCTGAGTGA
CATGGACATCAACGCCATCGCCGGGACGCTCAAGCTGTACTTCCGGGAACTGCCCGAGCCGCTCCTCACGGACCGACTCTACCCAGCCTT
CATGGAGGGCATCGCCCTGTCAGACCCTGCTGCCAAGGAAAACTGCATGATGCACCTGCTCCGCTCCCTGCCCGACCCCAACCTCATCAC
CTTCCTCTTCCTGCTGGAACACTTGAAAAGGGTTGCCGAGAAGGAGCCCATCAACAAAATGTCACTTCACAACCTGGCTACCGTGTTTGG
ACCCACGTTACTGAGACCCTCAGAAGTGGAGAGCAAAGCACACCTCACCTCGGCTGCGGACATCTGGTCCCATGACGTCATGGCGCAGGT
CCAGGTCCTCCTCTACTACCTGCAGCACCCCCCCATTTCCTTCGCAGAACTCAAGCGGAACACACTGTACTTCTCCACCGACGTGTAGCC
CGAGGCAGGGTGGCTGCGGGCGGGTGGTGGAACCAGCCCCTCCAGCCTGGGGTCCAACTCAGACTTGAAAGACTGCAATAGAAAACTCCC
AAACCCAGCACTCCAGACTCGAGGGAAGCCAGCTTCCAAGAACTGGAATGCGTACGTCTTTTGTGCCACCTTGTACAAAGCCGGCTGCCC
AGCCCCAGCCTCACCACCGCATCCCACCTCCTGCCCTCCATACCTCTAGTTGTGTCTGATGCTCCGTGCTGTTCGGGAATTGTTTTATGT
ACACTTGTCAGGCAGAAAAGGTAGTGACCGGCCCGGCGTGGGCACACAGACAGCCCGCTTTGTTCTTTCATTTCCTCCAGCACTTTCTTT
CCGCCTGAGTCCAGCCCAAGGCCTTTTATTTTGCGCTGTGTAACTGCTGCCAGCTTCTCTCTTGGCCCTGCTCCCAGATGGCGGTCTCCT
GGCAGCCTCCCCTCAGTCTTCCTCCACCCGCTCTTCCTTCCCAGCCTGCCTGCATGCATGTGCACCCTTGGTCTTCGCTCCATCGCCTTG
AAAGCTCTGAAGAGGCCCTGGGTTGCCGCGGCAGCAGTGGTCTGTTTGATGCTGCCGTTTGCCGCTGCCGGCCCCTCCTCAGACTCCGCC
TTTGGGAGCACACCTGCTTTGCCTTGCTGCCTGTGCAAATGTTGGACAAGCAGACACACTCACACTCGTCCCCAGCTTAGCACAGAGCTG
GAGCGCCCATTTCTGGAATTTTCCGTTTGGGAATCTCCACTTCTGGGGTTTACCTGTTCGGCCTCCTGTCTATCAGTGAGGCATCTCTGA
CTGTTTCTTCTACTGCTTTTCAGTTCCCTTCCCTGCTGTTCTATTTCCTTTGAGTGTAAAGACTCACAGGTGACCTGCTATCGAGATAGC
CAGAGGGTCAGGAGAGAATGGGGGAGGAGGCGGTCAGGCTGCTGAGGAAACACCACAGGCTGAACGGGGGAGGAATGCACATGCCACGCT
GGGTGTCCCGGGTCGCGGGGAGGCAGCTCAGCTCTTAGGAGCAAGTTGTGGGGGCTTTTCAAGAGGGGCCAGGCTTCCTGGAGGGTGACT
GATGTGGCCGAAGCAGGTGTCCAGGCAGGTAGGCTGCAGCCAGGAGCTCCCTGGCACCGCAGGACCTCGTGGTACTCTTGCCTTAGATTT
TACACACACTCCACAGCCAAGCACTGCCACGGTCCTCCAGGACCTGGGAAGCAAAGGCACAGGCCCACGGTGGCCAGCCATTGTGGTGCC
GCCCCAGCTTCTGGATACAGCCTTTTGGGTAAACACTGGGAACTCCAGAAGTTGTGGGGAGAGTGGGGAATCAGACAGCCGCCTCTAGGG
GCTGGGTTCTGCTGGGGCCTCCTTGTTGGTGCTGTAGGCACCCGCCAGGGAGCAGGGACCCGACTTGCAGACGCATTGCCCGGTACTAGG
AAGGAGTGAGGTGTGTTCCCACCGTACACTTCCCACACGAGCTGCGGCTGCCAGCCTCGGGCCATCAGCCTAGGAGAGCAGATGCAGCTC
CAGGGGCTCGACTTATAGCCAGTTACAGCTCCCCGGCTCTTCTGTGTGGCAGAGCGTCGTTTCCGGGCCCTCAGGGCTGGGGAGCTCAGT
TCCCATTGCTTGTGCTCAGGGCTGAGTCTTAAAGAAGGGTTTGCCGGCCCTAACGCTGCAGCGCGTGCGCGGTGAGAGGCCCTTTTTGAG
CCTGTTTACTCCTGTGGCCTTGGGCAGAACAGTAAATACTCTGTGCACGGAGGAAAGACATGCCCAAGAGGAAGGAAGTACTGACCATCG
GCTGCCTGTGAGCAGCTTAGCAAGGAGCCCTTGCTCCCTGGGAAAGGCGGTGAACTTGAGTCTAAAGATGCAGTGCCTGGCCCTTCCTAA
GGTCCCTGCCTGGCATCCGAGTGTCGGTGTGTGGCACAGAAGGCTCCTGCTTGCTTCCAAAGTGATGGACAGGAAGGGGCAGAGTGAGTC
ACGGCCCAGACTGGGCACCTTCGCGTCTCAGCCTCAGGGAGCCCCACAGCCCCAAGCTCGCTGAGGCAACGTGAGAACAGGCTATGGGAA
GGCTGCAAAGGCTGAGAAATGCAAAGGCTCATATTTATAAATCCCACCCCCAGAGTGGGGAGGGTCAGGTGCCAGACCTGGACTAAACTG
CACCAAGGAAACACCCAGCAGGGTCTCCTGTGAGCCGGGGACCATGCAGCCCGAAACCTCCAGTCACTGCGCCCGGCAGGAGTCAGGAGC
CAGGGACTGTGCAGCCTGGAACCTCCAGTCACTGTGCCCAGCAGGGTGGGCTGTGCCCAGCAGGAGTCAGGCTAAGAAACGCCAGGTCTG
CCTGTTCTTGCTGGGCAATGGCTGATGGCTGCCAGTTTCTGCTGATACACAGGTAGGATGGGACCCTTCATGAATATCTGACTTTAATAA
GTTGGTAAGGATATATTTTTTTGTCTATGTTCTGTTTCAACTTATGTAGATTATTATAAATTGATGTAAACCACGTGAGAGGAAAATGTT

>80385_80385_3_SENP3-ABR_SENP3_chr17_7470322_ENST00000429205_ABR_chr17_962107_ENST00000302538_length(amino acids)=912AA_BP=447
MKETIQGTGSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPARRLPVPRPSFDASASEEEEEEEEEEDEDEE
EEVAAWRLPPRWSQLGTSQRPRPSRPTHRKTCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRGLAHPKNHLSPQQGGATPQVP
SPCCRFDSPRGPPPPRLGLLGALMAEDGVRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGQSGPEGERSLAPPDASILI
SNVCSIGDHVAQELFQGSDLGMAEEAERPGEKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKGLV
LQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEKVHFFNSFFYDKLRTKGYDGVKRWTKNKAN
KGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHN
IPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKT
KVNKDNNEIVDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQC
VEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCM
MHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFAE

--------------------------------------------------------------
>80385_80385_4_SENP3-ABR_SENP3_chr17_7470322_ENST00000429205_ABR_chr17_962107_ENST00000544583_length(transcript)=5341nt_BP=1390nt
CCGCCTTCGGGCCCGTCCGCCCGGCTTCCCCGCTCCCGGGTACTGGAAGATGAAAGAGACTATACAAGGGACCGGGTCCTGGGGGCCTGA
GCCTCCTGGACCCGGCATACCCCCAGCTTACTCAAGTCCCAGGCGGGAGCGTCTTCGTTGGCCCCCACCTCCCAAACCCCGACTCAAGTC
AGGTGGAGGGTTTGGGCCAGATCCTGGGTCAGGGACCACAGTGCCAGCCAGACGCCTCCCTGTCCCCCGACCCTCTTTTGATGCCTCAGC
AAGTGAAGAGGAGGAAGAAGAGGAGGAGGAGGAGGATGAAGATGAAGAGGAGGAAGTGGCAGCTTGGAGGCTGCCCCCAAGATGGAGTCA
GCTGGGAACCTCCCAGCGGCCCCGCCCTTCCCGCCCCACTCATCGAAAAACCTGCTCACAGCGCCGCCGCCGAGCCATGAGAGCCTTCCG
GATGCTGCTCTACTCAAAAAGCACCTCGCTGACATTCCACTGGAAGCTTTGGGGGCGCCACCGGGGCCGGCGGCGGGGCCTCGCACACCC
CAAGAACCATCTTTCACCCCAGCAAGGGGGTGCGACGCCACAGGTGCCATCCCCCTGTTGTCGTTTTGACTCCCCCCGGGGGCCACCTCC
ACCCCGGCTGGGTCTGCTAGGTGCTCTCATGGCTGAGGATGGGGTGAGAGGGTCTCCACCAGTGCCCTCTGGGCCCCCCATGGAGGAAGA
TGGACTCAGGTGGACTCCAAAGTCTCCTCTGGACCCTGACTCGGGCCTCCTTTCATGTACTCTGCCCAACGGTTTTGGGGGACAATCTGG
GCCAGAAGGGGAGCGCAGCTTGGCACCCCCTGATGCCAGCATCCTCATCAGCAATGTGTGCAGCATCGGGGACCATGTGGCCCAGGAGCT
TTTTCAGGGCTCAGATTTGGGCATGGCAGAAGAGGCAGAGAGGCCTGGGGAGAAAGCCGGCCAGCACAGCCCCCTGCGAGAGGAGCATGT
GACCTGCGTACAGAGCATCTTGGACGAATTCCTTCAAACGTATGGCAGCCTCATACCCCTCAGCACTGATGAGGTAGTAGAGAAGCTGGA
GGACATTTTCCAGCAGGAGTTTTCCACCCCTTCCAGGAAGGGCCTGGTGTTGCAGCTGATCCAGTCTTACCAGCGGATGCCAGGCAATGC
CATGGTGAGGGGCTTCCGAGTGGCTTATAAGCGGCACGTGCTGACCATGGATGACTTGGGGACCTTGTATGGACAGAACTGGCTCAATGA
CCAGGTGATGAACATGTATGGAGACCTGGTCATGGACACAGTCCCTGAAAAGGTGCATTTCTTCAATAGTTTCTTCTATGATAAACTCCG
TACCAAGGGTTATGATGGGGTGAAAAGGTGGACCAAAAACAAAGCCAACAAAGGCCAGAGCCGGGCCATCGAGCGCCTGAAGAAGAAGAT
GTTTGAGAATGAGTTCCTGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAATCGGAATGGAAAGAGTTACCTGTTCCTACT
GTCCTCGGACTACGAGAGGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGATCTCCAGGCCTTTGTCCTGAGCTCAGTGGA
GCTCCAGGTGCTCACAGGATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACCAGCAATAAAGACGACGATGAGTCTCCAGG
ACTCTATGGCTTCCTTCATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAACCTGTACTGTACCCTGGAGGTGGATTCCTT
CGGCTATTTTGTCAGCAAAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGGGATGAGGAGTTTGAGATCGAGCTGGAGGG
CTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAGGACAACAATGAGATCGTGGACAAGATCAT
GGGCAAAGGACAGATCCAGCTGGACCCACAAACCGTGGAGACCAAGAACTGGCACACGGACGTGATTGAGATGAACGGGATCAAAGTGGA
ATTTTCCATGAAATTCACCAGCCGAGATATGAGCCTGAAGAGGACCCCGTCCAAAAAGCAGACCGGCGTCTTCGGTGTGAAGATCAGCGT
GGTGACGAAGCGGGAGCGCTCCAAGGTGCCCTACATCGTCCGGCAGTGTGTGGAGGAGGTGGAGAAGAGGGGTATCGAGGAGGTTGGCAT
CTACAGGATATCGGGCGTGGCCACGGACATCCAGGCGCTCAAGGCCGTCTTCGATGCCAATAACAAGGACATCCTGCTGATGCTGAGTGA
CATGGACATCAACGCCATCGCCGGGACGCTCAAGCTGTACTTCCGGGAACTGCCCGAGCCGCTCCTCACGGACCGACTCTACCCAGCCTT
CATGGAGGGCATCGCCCTGTCAGACCCTGCTGCCAAGGAAAACTGCATGATGCACCTGCTCCGCTCCCTGCCCGACCCCAACCTCATCAC
CTTCCTCTTCCTGCTGGAACACTTGAAAAGGGTTGCCGAGAAGGAGCCCATCAACAAAATGTCACTTCACAACCTGGCTACCGTGTTTGG
ACCCACGTTACTGAGACCCTCAGAAGTGGAGAGCAAAGCACACCTCACCTCGGCTGCGGACATCTGGTCCCATGACGTCATGGCGCAGGT
CCAGGTCCTCCTCTACTACCTGCAGCACCCCCCCATTTCCTTCGCAGAACTCAAGCGGAACACACTGTACTTCTCCACCGACGTGTAGCC
CGAGGCAGGGTGGCTGCGGGCGGGTGGTGGAACCAGCCCCTCCAGCCTGGGGTCCAACTCAGACTTGAAAGACTGCAATAGAAAACTCCC
AAACCCAGCACTCCAGACTCGAGGGAAGCCAGCTTCCAAGAACTGGAATGCGTACGTCTTTTGTGCCACCTTGTACAAAGCCGGCTGCCC
AGCCCCAGCCTCACCACCGCATCCCACCTCCTGCCCTCCATACCTCTAGTTGTGTCTGATGCTCCGTGCTGTTCGGGAATTGTTTTATGT
ACACTTGTCAGGCAGAAAAGGTAGTGACCGGCCCGGCGTGGGCACACAGACAGCCCGCTTTGTTCTTTCATTTCCTCCAGCACTTTCTTT
CCGCCTGAGTCCAGCCCAAGGCCTTTTATTTTGCGCTGTGTAACTGCTGCCAGCTTCTCTCTTGGCCCTGCTCCCAGATGGCGGTCTCCT
GGCAGCCTCCCCTCAGTCTTCCTCCACCCGCTCTTCCTTCCCAGCCTGCCTGCATGCATGTGCACCCTTGGTCTTCGCTCCATCGCCTTG
AAAGCTCTGAAGAGGCCCTGGGTTGCCGCGGCAGCAGTGGTCTGTTTGATGCTGCCGTTTGCCGCTGCCGGCCCCTCCTCAGACTCCGCC
TTTGGGAGCACACCTGCTTTGCCTTGCTGCCTGTGCAAATGTTGGACAAGCAGACACACTCACACTCGTCCCCAGCTTAGCACAGAGCTG
GAGCGCCCATTTCTGGAATTTTCCGTTTGGGAATCTCCACTTCTGGGGTTTACCTGTTCGGCCTCCTGTCTATCAGTGAGGCATCTCTGA
CTGTTTCTTCTACTGCTTTTCAGTTCCCTTCCCTGCTGTTCTATTTCCTTTGAGTGTAAAGACTCACAGGTGACCTGCTATCGAGATAGC
CAGAGGGTCAGGAGAGAATGGGGGAGGAGGCGGTCAGGCTGCTGAGGAAACACCACAGGCTGAACGGGGGAGGAATGCACATGCCACGCT
GGGTGTCCCGGGTCGCGGGGAGGCAGCTCAGCTCTTAGGAGCAAGTTGTGGGGGCTTTTCAAGAGGGGCCAGGCTTCCTGGAGGGTGACT
GATGTGGCCGAAGCAGGTGTCCAGGCAGGTAGGCTGCAGCCAGGAGCTCCCTGGCACCGCAGGACCTCGTGGTACTCTTGCCTTAGATTT
TACACACACTCCACAGCCAAGCACTGCCACGGTCCTCCAGGACCTGGGAAGCAAAGGCACAGGCCCACGGTGGCCAGCCATTGTGGTGCC
GCCCCAGCTTCTGGATACAGCCTTTTGGGTAAACACTGGGAACTCCAGAAGTTGTGGGGAGAGTGGGGAATCAGACAGCCGCCTCTAGGG
GCTGGGTTCTGCTGGGGCCTCCTTGTTGGTGCTGTAGGCACCCGCCAGGGAGCAGGGACCCGACTTGCAGACGCATTGCCCGGTACTAGG
AAGGAGTGAGGTGTGTTCCCACCGTACACTTCCCACACGAGCTGCGGCTGCCAGCCTCGGGCCATCAGCCTAGGAGAGCAGATGCAGCTC
CAGGGGCTCGACTTATAGCCAGTTACAGCTCCCCGGCTCTTCTGTGTGGCAGAGCGTCGTTTCCGGGCCCTCAGGGCTGGGGAGCTCAGT
TCCCATTGCTTGTGCTCAGGGCTGAGTCTTAAAGAAGGGTTTGCCGGCCCTAACGCTGCAGCGCGTGCGCGGTGAGAGGCCCTTTTTGAG
CCTGTTTACTCCTGTGGCCTTGGGCAGAACAGTAAATACTCTGTGCACGGAGGAAAGACATGCCCAAGAGGAAGGAAGTACTGACCATCG
GCTGCCTGTGAGCAGCTTAGCAAGGAGCCCTTGCTCCCTGGGAAAGGCGGTGAACTTGAGTCTAAAGATGCAGTGCCTGGCCCTTCCTAA
GGTCCCTGCCTGGCATCCGAGTGTCGGTGTGTGGCACAGAAGGCTCCTGCTTGCTTCCAAAGTGATGGACAGGAAGGGGCAGAGTGAGTC
ACGGCCCAGACTGGGCACCTTCGCGTCTCAGCCTCAGGGAGCCCCACAGCCCCAAGCTCGCTGAGGCAACGTGAGAACAGGCTATGGGAA
GGCTGCAAAGGCTGAGAAATGCAAAGGCTCATATTTATAAATCCCACCCCCAGAGTGGGGAGGGTCAGGTGCCAGACCTGGACTAAACTG
CACCAAGGAAACACCCAGCAGGGTCTCCTGTGAGCCGGGGACCATGCAGCCCGAAACCTCCAGTCACTGCGCCCGGCAGGAGTCAGGAGC
CAGGGACTGTGCAGCCTGGAACCTCCAGTCACTGTGCCCAGCAGGGTGGGCTGTGCCCAGCAGGAGTCAGGCTAAGAAACGCCAGGTCTG
CCTGTTCTTGCTGGGCAATGGCTGATGGCTGCCAGTTTCTGCTGATACACAGGTAGGATGGGACCCTTCATGAATATCTGACTTTAATAA
GTTGGTAAGGATATATTTTTTTGTCTATGTTCTGTTTCAACTTATGTAGATTATTATAAATTGATGTAAACCACGTGAGAGGAAAATGTT

>80385_80385_4_SENP3-ABR_SENP3_chr17_7470322_ENST00000429205_ABR_chr17_962107_ENST00000544583_length(amino acids)=912AA_BP=447
MKETIQGTGSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPARRLPVPRPSFDASASEEEEEEEEEEDEDEE
EEVAAWRLPPRWSQLGTSQRPRPSRPTHRKTCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRGLAHPKNHLSPQQGGATPQVP
SPCCRFDSPRGPPPPRLGLLGALMAEDGVRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGQSGPEGERSLAPPDASILI
SNVCSIGDHVAQELFQGSDLGMAEEAERPGEKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKGLV
LQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEKVHFFNSFFYDKLRTKGYDGVKRWTKNKAN
KGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHN
IPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKT
KVNKDNNEIVDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQC
VEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCM
MHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFAE

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Fusion Gene PPI Analysis for SENP3-ABR


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SENP3-ABR


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SENP3-ABR


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0033578Prostatic Neoplasms1CTD_human
TgeneC0376358Malignant neoplasm of prostate1CTD_human