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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EIF2C2-PTK2 (FusionGDB2 ID:HG27161TG5747)

Fusion Gene Summary for EIF2C2-PTK2

check button Fusion gene summary
Fusion gene informationFusion gene name: EIF2C2-PTK2
Fusion gene ID: hg27161tg5747
HgeneTgene
Gene symbol

EIF2C2

PTK2

Gene ID

27161

5747

Gene nameargonaute RISC catalytic component 2protein tyrosine kinase 2
SynonymsCASC7|EIF2C2|LINC00980|PPD|Q10FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK
Cytomap('AGO2','EIF2C2')('PTK2','PTK2')

8q24.3

8q24.3

Type of geneprotein-codingprotein-coding
Descriptionprotein argonaute-2PAZ Piwi domain proteinargonaute 2, RISC catalytic componentcancer susceptibility candidate 7cancer susceptibility candidate 7 (non-protein coding)eukaryotic translation initiation factor 2C, 2long intergenic non-protein coding RNfocal adhesion kinase 1FADK 1FAK-related non-kinase polypeptidePTK2 protein tyrosine kinase 2focal adhesion kinase isoform FAK-Del33focal adhesion kinase-related nonkinaseprotein phosphatase 1 regulatory subunit 71
Modification date2020032720200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000220592, ENST00000519980, 
ENST00000517293, 
ENST00000517293, 
ENST00000519980, ENST00000220592, 
Fusion gene scores* DoF score13 X 13 X 12=202819 X 20 X 13=4940
# samples 2829
** MAII scorelog2(28/2028*10)=-2.85655892005837
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(29/4940*10)=-4.09038623645711
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EIF2C2 [Title/Abstract] AND PTK2 [Title/Abstract] AND fusion [Title/Abstract]

Germline AGO2 mutations impair RNA interference and human neurological development (pmid: 33199684)
Most frequent breakpointAGO2(141645584)-PTK2(141685598), # samples:3
EIF2C2(141645584)-PTK2(141685598), # samples:1
EIF2C2(141645584)-PTK2(141712806), # samples:1
EIF2C2(141645584)-PTK2(141678523), # samples:1
EIF2C2(141645584)-PTK2(141874498), # samples:1
EIF2C2(141645584)-PTK2(141696793), # samples:1
Anticipated loss of major functional domain due to fusion event.AGO2-PTK2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
AGO2-PTK2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
AGO2-PTK2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
AGO2-PTK2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
PTK2-AGO2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PTK2-AGO2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
AGO2-PTK2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
AGO2-PTK2 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
AGO2-PTK2 seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
PTK2-AGO2 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
PTK2-AGO2 seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF.
PTK2-AGO2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneEIF2C2

GO:0010501

RNA secondary structure unwinding

19966796

HgeneEIF2C2

GO:0031054

pre-miRNA processing

16424907|17671087|18178619|19966796

HgeneEIF2C2

GO:0035087

siRNA loading onto RISC involved in RNA interference

19966796

HgeneEIF2C2

GO:0035196

production of miRNAs involved in gene silencing by miRNA

19966796|23661684

HgeneEIF2C2

GO:0035278

miRNA mediated inhibition of translation

17671087|19801630

HgeneEIF2C2

GO:0035279

mRNA cleavage involved in gene silencing by miRNA

15260970|17524464

HgeneEIF2C2

GO:0035280

miRNA loading onto RISC involved in gene silencing by miRNA

18178619|19966796

HgeneEIF2C2

GO:0045766

positive regulation of angiogenesis

27208409

HgeneEIF2C2

GO:0045947

negative regulation of translational initiation

17524464|19801630

HgeneEIF2C2

GO:0090625

mRNA cleavage involved in gene silencing by siRNA

15260970

HgeneEIF2C2

GO:1905618

positive regulation of miRNA mediated inhibition of translation

23409027

TgenePTK2

GO:0007179

transforming growth factor beta receptor signaling pathway

24036928

TgenePTK2

GO:0007229

integrin-mediated signaling pathway

24036928

TgenePTK2

GO:0010763

positive regulation of fibroblast migration

26763945

TgenePTK2

GO:0018108

peptidyl-tyrosine phosphorylation

10655584|11331870

TgenePTK2

GO:0022408

negative regulation of cell-cell adhesion

21703394

TgenePTK2

GO:0030335

positive regulation of cell migration

11331870|21703394

TgenePTK2

GO:0033628

regulation of cell adhesion mediated by integrin

10655584

TgenePTK2

GO:0046777

protein autophosphorylation

10655584|11331870

TgenePTK2

GO:0048013

ephrin receptor signaling pathway

10655584

TgenePTK2

GO:0060396

growth hormone receptor signaling pathway

10925297

TgenePTK2

GO:0090303

positive regulation of wound healing

26763945


check buttonFusion gene breakpoints across AGO2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across PTK2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-C8-A26Y-01AAGO2chr8

141645584

-PTK2chr8

141678523

-
ChimerDB4BRCATCGA-C8-A26Y-01AEIF2C2chr8

141645584

-PTK2chr8

141678523

-
ChimerDB4BRCATCGA-E2-A1II-01AEIF2C2chr8

141645584

-PTK2chr8

141874498

-
ChimerDB4BRCATCGA-E2-A1LE-01AEIF2C2chr8

141645584

-PTK2chr8

141696793

-
ChimerDB4LUSCTCGA-60-2713-01AEIF2C2chr8

141645584

-PTK2chr8

141685598

-
ChimerDB4LUSCTCGA-60-2713AGO2chr8

141645584

-PTK2chr8

141685598

-
ChimerDB4OVTCGA-13-1481-01AAGO2chr8

141645584

-PTK2chr8

141685598

-
ChimerDB4OVTCGA-13-1487-01AAGO2chr8

141645584

-PTK2chr8

141675096

-
ChimerDB4OVTCGA-13-1512-01AAGO2chr8

141645584

-PTK2chr8

141684503

-
ChimerDB4OVTCGA-13-1512-01AAGO2chr8

141645584

-PTK2chr8

141685598

-
ChimerDB4OVTCGA-36-1570-01AAGO2chr8

141645584

-PTK2chr8

141762415

-
ChimerDB4OVTCGA-61-2109-01AAGO2chr8

141645584

-PTK2chr8

141712806

-
ChimerDB4OVTCGA-61-2109-01AEIF2C2chr8

141645584

-PTK2chr8

141712806

-
ChimerDB4UCECTCGA-FI-A2CY-01AAGO2chr8

141645584

-PTK2chr8

141669777

-


Top

Fusion Gene ORF analysis for EIF2C2-PTK2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000220592ENST00000522950AGO2chr8

141645584

-PTK2chr8

141669777

-
5CDS-3UTRENST00000519980ENST00000522950AGO2chr8

141645584

-PTK2chr8

141669777

-
5CDS-5UTRENST00000220592ENST00000517712AGO2chr8

141645584

-PTK2chr8

141678523

-
5CDS-5UTRENST00000519980ENST00000517712AGO2chr8

141645584

-PTK2chr8

141678523

-
5CDS-intronENST00000220592ENST00000340930AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000220592ENST00000395218AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000220592ENST00000430260AGO2chr8

141645584

-PTK2chr8

141762415

-
5CDS-intronENST00000220592ENST00000430260AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000220592ENST00000517712AGO2chr8

141645584

-PTK2chr8

141685598

-
5CDS-intronENST00000220592ENST00000517712AGO2chr8

141645584

-PTK2chr8

141675096

-
5CDS-intronENST00000220592ENST00000517712AGO2chr8

141645584

-PTK2chr8

141684503

-
5CDS-intronENST00000220592ENST00000517712AGO2chr8

141645584

-PTK2chr8

141762415

-
5CDS-intronENST00000220592ENST00000517712AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000220592ENST00000517712AGO2chr8

141645584

-PTK2chr8

141669777

-
5CDS-intronENST00000220592ENST00000517887AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000220592ENST00000519419AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000220592ENST00000519465AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000220592ENST00000519635AGO2chr8

141645584

-PTK2chr8

141678523

-
5CDS-intronENST00000220592ENST00000519635AGO2chr8

141645584

-PTK2chr8

141685598

-
5CDS-intronENST00000220592ENST00000519635AGO2chr8

141645584

-PTK2chr8

141675096

-
5CDS-intronENST00000220592ENST00000519635AGO2chr8

141645584

-PTK2chr8

141684503

-
5CDS-intronENST00000220592ENST00000519635AGO2chr8

141645584

-PTK2chr8

141762415

-
5CDS-intronENST00000220592ENST00000519635AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000220592ENST00000519635AGO2chr8

141645584

-PTK2chr8

141669777

-
5CDS-intronENST00000220592ENST00000519881AGO2chr8

141645584

-PTK2chr8

141678523

-
5CDS-intronENST00000220592ENST00000519881AGO2chr8

141645584

-PTK2chr8

141685598

-
5CDS-intronENST00000220592ENST00000519881AGO2chr8

141645584

-PTK2chr8

141675096

-
5CDS-intronENST00000220592ENST00000519881AGO2chr8

141645584

-PTK2chr8

141684503

-
5CDS-intronENST00000220592ENST00000519881AGO2chr8

141645584

-PTK2chr8

141762415

-
5CDS-intronENST00000220592ENST00000519881AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000220592ENST00000519881AGO2chr8

141645584

-PTK2chr8

141669777

-
5CDS-intronENST00000220592ENST00000520151AGO2chr8

141645584

-PTK2chr8

141678523

-
5CDS-intronENST00000220592ENST00000520151AGO2chr8

141645584

-PTK2chr8

141685598

-
5CDS-intronENST00000220592ENST00000520151AGO2chr8

141645584

-PTK2chr8

141675096

-
5CDS-intronENST00000220592ENST00000520151AGO2chr8

141645584

-PTK2chr8

141684503

-
5CDS-intronENST00000220592ENST00000520151AGO2chr8

141645584

-PTK2chr8

141762415

-
5CDS-intronENST00000220592ENST00000520151AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000220592ENST00000520151AGO2chr8

141645584

-PTK2chr8

141669777

-
5CDS-intronENST00000220592ENST00000520892AGO2chr8

141645584

-PTK2chr8

141678523

-
5CDS-intronENST00000220592ENST00000520892AGO2chr8

141645584

-PTK2chr8

141685598

-
5CDS-intronENST00000220592ENST00000520892AGO2chr8

141645584

-PTK2chr8

141675096

-
5CDS-intronENST00000220592ENST00000520892AGO2chr8

141645584

-PTK2chr8

141684503

-
5CDS-intronENST00000220592ENST00000520892AGO2chr8

141645584

-PTK2chr8

141762415

-
5CDS-intronENST00000220592ENST00000520892AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000220592ENST00000520892AGO2chr8

141645584

-PTK2chr8

141669777

-
5CDS-intronENST00000220592ENST00000521059AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000220592ENST00000522950AGO2chr8

141645584

-PTK2chr8

141678523

-
5CDS-intronENST00000220592ENST00000522950AGO2chr8

141645584

-PTK2chr8

141685598

-
5CDS-intronENST00000220592ENST00000522950AGO2chr8

141645584

-PTK2chr8

141675096

-
5CDS-intronENST00000220592ENST00000522950AGO2chr8

141645584

-PTK2chr8

141684503

-
5CDS-intronENST00000220592ENST00000522950AGO2chr8

141645584

-PTK2chr8

141762415

-
5CDS-intronENST00000220592ENST00000522950AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000220592ENST00000535192AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000220592ENST00000538769AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000519980ENST00000340930AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000519980ENST00000395218AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000519980ENST00000430260AGO2chr8

141645584

-PTK2chr8

141762415

-
5CDS-intronENST00000519980ENST00000430260AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000519980ENST00000517712AGO2chr8

141645584

-PTK2chr8

141685598

-
5CDS-intronENST00000519980ENST00000517712AGO2chr8

141645584

-PTK2chr8

141675096

-
5CDS-intronENST00000519980ENST00000517712AGO2chr8

141645584

-PTK2chr8

141684503

-
5CDS-intronENST00000519980ENST00000517712AGO2chr8

141645584

-PTK2chr8

141762415

-
5CDS-intronENST00000519980ENST00000517712AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000519980ENST00000517712AGO2chr8

141645584

-PTK2chr8

141669777

-
5CDS-intronENST00000519980ENST00000517887AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000519980ENST00000519419AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000519980ENST00000519465AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000519980ENST00000519635AGO2chr8

141645584

-PTK2chr8

141678523

-
5CDS-intronENST00000519980ENST00000519635AGO2chr8

141645584

-PTK2chr8

141685598

-
5CDS-intronENST00000519980ENST00000519635AGO2chr8

141645584

-PTK2chr8

141675096

-
5CDS-intronENST00000519980ENST00000519635AGO2chr8

141645584

-PTK2chr8

141684503

-
5CDS-intronENST00000519980ENST00000519635AGO2chr8

141645584

-PTK2chr8

141762415

-
5CDS-intronENST00000519980ENST00000519635AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000519980ENST00000519635AGO2chr8

141645584

-PTK2chr8

141669777

-
5CDS-intronENST00000519980ENST00000519881AGO2chr8

141645584

-PTK2chr8

141678523

-
5CDS-intronENST00000519980ENST00000519881AGO2chr8

141645584

-PTK2chr8

141685598

-
5CDS-intronENST00000519980ENST00000519881AGO2chr8

141645584

-PTK2chr8

141675096

-
5CDS-intronENST00000519980ENST00000519881AGO2chr8

141645584

-PTK2chr8

141684503

-
5CDS-intronENST00000519980ENST00000519881AGO2chr8

141645584

-PTK2chr8

141762415

-
5CDS-intronENST00000519980ENST00000519881AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000519980ENST00000519881AGO2chr8

141645584

-PTK2chr8

141669777

-
5CDS-intronENST00000519980ENST00000520151AGO2chr8

141645584

-PTK2chr8

141678523

-
5CDS-intronENST00000519980ENST00000520151AGO2chr8

141645584

-PTK2chr8

141685598

-
5CDS-intronENST00000519980ENST00000520151AGO2chr8

141645584

-PTK2chr8

141675096

-
5CDS-intronENST00000519980ENST00000520151AGO2chr8

141645584

-PTK2chr8

141684503

-
5CDS-intronENST00000519980ENST00000520151AGO2chr8

141645584

-PTK2chr8

141762415

-
5CDS-intronENST00000519980ENST00000520151AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000519980ENST00000520151AGO2chr8

141645584

-PTK2chr8

141669777

-
5CDS-intronENST00000519980ENST00000520892AGO2chr8

141645584

-PTK2chr8

141678523

-
5CDS-intronENST00000519980ENST00000520892AGO2chr8

141645584

-PTK2chr8

141685598

-
5CDS-intronENST00000519980ENST00000520892AGO2chr8

141645584

-PTK2chr8

141675096

-
5CDS-intronENST00000519980ENST00000520892AGO2chr8

141645584

-PTK2chr8

141684503

-
5CDS-intronENST00000519980ENST00000520892AGO2chr8

141645584

-PTK2chr8

141762415

-
5CDS-intronENST00000519980ENST00000520892AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000519980ENST00000520892AGO2chr8

141645584

-PTK2chr8

141669777

-
5CDS-intronENST00000519980ENST00000521059AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000519980ENST00000522950AGO2chr8

141645584

-PTK2chr8

141678523

-
5CDS-intronENST00000519980ENST00000522950AGO2chr8

141645584

-PTK2chr8

141685598

-
5CDS-intronENST00000519980ENST00000522950AGO2chr8

141645584

-PTK2chr8

141675096

-
5CDS-intronENST00000519980ENST00000522950AGO2chr8

141645584

-PTK2chr8

141684503

-
5CDS-intronENST00000519980ENST00000522950AGO2chr8

141645584

-PTK2chr8

141762415

-
5CDS-intronENST00000519980ENST00000522950AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000519980ENST00000535192AGO2chr8

141645584

-PTK2chr8

141712806

-
5CDS-intronENST00000519980ENST00000538769AGO2chr8

141645584

-PTK2chr8

141712806

-
5UTR-3CDSENST00000517293ENST00000340930AGO2chr8

141645584

-PTK2chr8

141678523

-
5UTR-3CDSENST00000517293ENST00000340930AGO2chr8

141645584

-PTK2chr8

141685598

-
5UTR-3CDSENST00000517293ENST00000340930AGO2chr8

141645584

-PTK2chr8

141675096

-
5UTR-3CDSENST00000517293ENST00000340930AGO2chr8

141645584

-PTK2chr8

141684503

-
5UTR-3CDSENST00000517293ENST00000340930AGO2chr8

141645584

-PTK2chr8

141762415

-
5UTR-3CDSENST00000517293ENST00000340930AGO2chr8

141645584

-PTK2chr8

141669777

-
5UTR-3CDSENST00000517293ENST00000395218AGO2chr8

141645584

-PTK2chr8

141678523

-
5UTR-3CDSENST00000517293ENST00000395218AGO2chr8

141645584

-PTK2chr8

141685598

-
5UTR-3CDSENST00000517293ENST00000395218AGO2chr8

141645584

-PTK2chr8

141675096

-
5UTR-3CDSENST00000517293ENST00000395218AGO2chr8

141645584

-PTK2chr8

141684503

-
5UTR-3CDSENST00000517293ENST00000395218AGO2chr8

141645584

-PTK2chr8

141762415

-
5UTR-3CDSENST00000517293ENST00000395218AGO2chr8

141645584

-PTK2chr8

141669777

-
5UTR-3CDSENST00000517293ENST00000430260AGO2chr8

141645584

-PTK2chr8

141678523

-
5UTR-3CDSENST00000517293ENST00000430260AGO2chr8

141645584

-PTK2chr8

141685598

-
5UTR-3CDSENST00000517293ENST00000430260AGO2chr8

141645584

-PTK2chr8

141675096

-
5UTR-3CDSENST00000517293ENST00000430260AGO2chr8

141645584

-PTK2chr8

141684503

-
5UTR-3CDSENST00000517293ENST00000430260AGO2chr8

141645584

-PTK2chr8

141669777

-
5UTR-3CDSENST00000517293ENST00000517887AGO2chr8

141645584

-PTK2chr8

141678523

-
5UTR-3CDSENST00000517293ENST00000517887AGO2chr8

141645584

-PTK2chr8

141685598

-
5UTR-3CDSENST00000517293ENST00000517887AGO2chr8

141645584

-PTK2chr8

141675096

-
5UTR-3CDSENST00000517293ENST00000517887AGO2chr8

141645584

-PTK2chr8

141684503

-
5UTR-3CDSENST00000517293ENST00000517887AGO2chr8

141645584

-PTK2chr8

141762415

-
5UTR-3CDSENST00000517293ENST00000517887AGO2chr8

141645584

-PTK2chr8

141669777

-
5UTR-3CDSENST00000517293ENST00000519419AGO2chr8

141645584

-PTK2chr8

141678523

-
5UTR-3CDSENST00000517293ENST00000519419AGO2chr8

141645584

-PTK2chr8

141685598

-
5UTR-3CDSENST00000517293ENST00000519419AGO2chr8

141645584

-PTK2chr8

141675096

-
5UTR-3CDSENST00000517293ENST00000519419AGO2chr8

141645584

-PTK2chr8

141684503

-
5UTR-3CDSENST00000517293ENST00000519419AGO2chr8

141645584

-PTK2chr8

141762415

-
5UTR-3CDSENST00000517293ENST00000519419AGO2chr8

141645584

-PTK2chr8

141669777

-
5UTR-3CDSENST00000517293ENST00000519465AGO2chr8

141645584

-PTK2chr8

141678523

-
5UTR-3CDSENST00000517293ENST00000519465AGO2chr8

141645584

-PTK2chr8

141685598

-
5UTR-3CDSENST00000517293ENST00000519465AGO2chr8

141645584

-PTK2chr8

141675096

-
5UTR-3CDSENST00000517293ENST00000519465AGO2chr8

141645584

-PTK2chr8

141684503

-
5UTR-3CDSENST00000517293ENST00000519465AGO2chr8

141645584

-PTK2chr8

141762415

-
5UTR-3CDSENST00000517293ENST00000519465AGO2chr8

141645584

-PTK2chr8

141669777

-
5UTR-3CDSENST00000517293ENST00000521059AGO2chr8

141645584

-PTK2chr8

141678523

-
5UTR-3CDSENST00000517293ENST00000521059AGO2chr8

141645584

-PTK2chr8

141685598

-
5UTR-3CDSENST00000517293ENST00000521059AGO2chr8

141645584

-PTK2chr8

141675096

-
5UTR-3CDSENST00000517293ENST00000521059AGO2chr8

141645584

-PTK2chr8

141684503

-
5UTR-3CDSENST00000517293ENST00000521059AGO2chr8

141645584

-PTK2chr8

141762415

-
5UTR-3CDSENST00000517293ENST00000521059AGO2chr8

141645584

-PTK2chr8

141669777

-
5UTR-3CDSENST00000517293ENST00000522684AGO2chr8

141645584

-PTK2chr8

141678523

-
5UTR-3CDSENST00000517293ENST00000522684AGO2chr8

141645584

-PTK2chr8

141685598

-
5UTR-3CDSENST00000517293ENST00000522684AGO2chr8

141645584

-PTK2chr8

141675096

-
5UTR-3CDSENST00000517293ENST00000522684AGO2chr8

141645584

-PTK2chr8

141684503

-
5UTR-3CDSENST00000517293ENST00000522684AGO2chr8

141645584

-PTK2chr8

141762415

-
5UTR-3CDSENST00000517293ENST00000522684AGO2chr8

141645584

-PTK2chr8

141712806

-
5UTR-3CDSENST00000517293ENST00000522684AGO2chr8

141645584

-PTK2chr8

141669777

-
5UTR-3CDSENST00000517293ENST00000535192AGO2chr8

141645584

-PTK2chr8

141678523

-
5UTR-3CDSENST00000517293ENST00000535192AGO2chr8

141645584

-PTK2chr8

141685598

-
5UTR-3CDSENST00000517293ENST00000535192AGO2chr8

141645584

-PTK2chr8

141675096

-
5UTR-3CDSENST00000517293ENST00000535192AGO2chr8

141645584

-PTK2chr8

141684503

-
5UTR-3CDSENST00000517293ENST00000535192AGO2chr8

141645584

-PTK2chr8

141762415

-
5UTR-3CDSENST00000517293ENST00000535192AGO2chr8

141645584

-PTK2chr8

141669777

-
5UTR-3CDSENST00000517293ENST00000538769AGO2chr8

141645584

-PTK2chr8

141678523

-
5UTR-3CDSENST00000517293ENST00000538769AGO2chr8

141645584

-PTK2chr8

141685598

-
5UTR-3CDSENST00000517293ENST00000538769AGO2chr8

141645584

-PTK2chr8

141675096

-
5UTR-3CDSENST00000517293ENST00000538769AGO2chr8

141645584

-PTK2chr8

141684503

-
5UTR-3CDSENST00000517293ENST00000538769AGO2chr8

141645584

-PTK2chr8

141762415

-
5UTR-3CDSENST00000517293ENST00000538769AGO2chr8

141645584

-PTK2chr8

141669777

-
5UTR-3UTRENST00000517293ENST00000522950AGO2chr8

141645584

-PTK2chr8

141669777

-
5UTR-5UTRENST00000517293ENST00000517712AGO2chr8

141645584

-PTK2chr8

141678523

-
5UTR-intronENST00000517293ENST00000340930AGO2chr8

141645584

-PTK2chr8

141712806

-
5UTR-intronENST00000517293ENST00000395218AGO2chr8

141645584

-PTK2chr8

141712806

-
5UTR-intronENST00000517293ENST00000430260AGO2chr8

141645584

-PTK2chr8

141762415

-
5UTR-intronENST00000517293ENST00000430260AGO2chr8

141645584

-PTK2chr8

141712806

-
5UTR-intronENST00000517293ENST00000517712AGO2chr8

141645584

-PTK2chr8

141685598

-
5UTR-intronENST00000517293ENST00000517712AGO2chr8

141645584

-PTK2chr8

141675096

-
5UTR-intronENST00000517293ENST00000517712AGO2chr8

141645584

-PTK2chr8

141684503

-
5UTR-intronENST00000517293ENST00000517712AGO2chr8

141645584

-PTK2chr8

141762415

-
5UTR-intronENST00000517293ENST00000517712AGO2chr8

141645584

-PTK2chr8

141712806

-
5UTR-intronENST00000517293ENST00000517712AGO2chr8

141645584

-PTK2chr8

141669777

-
5UTR-intronENST00000517293ENST00000517887AGO2chr8

141645584

-PTK2chr8

141712806

-
5UTR-intronENST00000517293ENST00000519419AGO2chr8

141645584

-PTK2chr8

141712806

-
5UTR-intronENST00000517293ENST00000519465AGO2chr8

141645584

-PTK2chr8

141712806

-
5UTR-intronENST00000517293ENST00000519635AGO2chr8

141645584

-PTK2chr8

141678523

-
5UTR-intronENST00000517293ENST00000519635AGO2chr8

141645584

-PTK2chr8

141685598

-
5UTR-intronENST00000517293ENST00000519635AGO2chr8

141645584

-PTK2chr8

141675096

-
5UTR-intronENST00000517293ENST00000519635AGO2chr8

141645584

-PTK2chr8

141684503

-
5UTR-intronENST00000517293ENST00000519635AGO2chr8

141645584

-PTK2chr8

141762415

-
5UTR-intronENST00000517293ENST00000519635AGO2chr8

141645584

-PTK2chr8

141712806

-
5UTR-intronENST00000517293ENST00000519635AGO2chr8

141645584

-PTK2chr8

141669777

-
5UTR-intronENST00000517293ENST00000519881AGO2chr8

141645584

-PTK2chr8

141678523

-
5UTR-intronENST00000517293ENST00000519881AGO2chr8

141645584

-PTK2chr8

141685598

-
5UTR-intronENST00000517293ENST00000519881AGO2chr8

141645584

-PTK2chr8

141675096

-
5UTR-intronENST00000517293ENST00000519881AGO2chr8

141645584

-PTK2chr8

141684503

-
5UTR-intronENST00000517293ENST00000519881AGO2chr8

141645584

-PTK2chr8

141762415

-
5UTR-intronENST00000517293ENST00000519881AGO2chr8

141645584

-PTK2chr8

141712806

-
5UTR-intronENST00000517293ENST00000519881AGO2chr8

141645584

-PTK2chr8

141669777

-
5UTR-intronENST00000517293ENST00000520151AGO2chr8

141645584

-PTK2chr8

141678523

-
5UTR-intronENST00000517293ENST00000520151AGO2chr8

141645584

-PTK2chr8

141685598

-
5UTR-intronENST00000517293ENST00000520151AGO2chr8

141645584

-PTK2chr8

141675096

-
5UTR-intronENST00000517293ENST00000520151AGO2chr8

141645584

-PTK2chr8

141684503

-
5UTR-intronENST00000517293ENST00000520151AGO2chr8

141645584

-PTK2chr8

141762415

-
5UTR-intronENST00000517293ENST00000520151AGO2chr8

141645584

-PTK2chr8

141712806

-
5UTR-intronENST00000517293ENST00000520151AGO2chr8

141645584

-PTK2chr8

141669777

-
5UTR-intronENST00000517293ENST00000520892AGO2chr8

141645584

-PTK2chr8

141678523

-
5UTR-intronENST00000517293ENST00000520892AGO2chr8

141645584

-PTK2chr8

141685598

-
5UTR-intronENST00000517293ENST00000520892AGO2chr8

141645584

-PTK2chr8

141675096

-
5UTR-intronENST00000517293ENST00000520892AGO2chr8

141645584

-PTK2chr8

141684503

-
5UTR-intronENST00000517293ENST00000520892AGO2chr8

141645584

-PTK2chr8

141762415

-
5UTR-intronENST00000517293ENST00000520892AGO2chr8

141645584

-PTK2chr8

141712806

-
5UTR-intronENST00000517293ENST00000520892AGO2chr8

141645584

-PTK2chr8

141669777

-
5UTR-intronENST00000517293ENST00000521059AGO2chr8

141645584

-PTK2chr8

141712806

-
5UTR-intronENST00000517293ENST00000522950AGO2chr8

141645584

-PTK2chr8

141678523

-
5UTR-intronENST00000517293ENST00000522950AGO2chr8

141645584

-PTK2chr8

141685598

-
5UTR-intronENST00000517293ENST00000522950AGO2chr8

141645584

-PTK2chr8

141675096

-
5UTR-intronENST00000517293ENST00000522950AGO2chr8

141645584

-PTK2chr8

141684503

-
5UTR-intronENST00000517293ENST00000522950AGO2chr8

141645584

-PTK2chr8

141762415

-
5UTR-intronENST00000517293ENST00000522950AGO2chr8

141645584

-PTK2chr8

141712806

-
5UTR-intronENST00000517293ENST00000535192AGO2chr8

141645584

-PTK2chr8

141712806

-
5UTR-intronENST00000517293ENST00000538769AGO2chr8

141645584

-PTK2chr8

141712806

-
Frame-shiftENST00000220592ENST00000340930AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000220592ENST00000340930AGO2chr8

141645584

-PTK2chr8

141669777

-
Frame-shiftENST00000220592ENST00000395218AGO2chr8

141645584

-PTK2chr8

141678523

-
Frame-shiftENST00000220592ENST00000395218AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000220592ENST00000395218AGO2chr8

141645584

-PTK2chr8

141669777

-
Frame-shiftENST00000220592ENST00000430260AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000220592ENST00000430260AGO2chr8

141645584

-PTK2chr8

141669777

-
Frame-shiftENST00000220592ENST00000517887AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000220592ENST00000517887AGO2chr8

141645584

-PTK2chr8

141669777

-
Frame-shiftENST00000220592ENST00000519419AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000220592ENST00000519419AGO2chr8

141645584

-PTK2chr8

141669777

-
Frame-shiftENST00000220592ENST00000519465AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000220592ENST00000519465AGO2chr8

141645584

-PTK2chr8

141669777

-
Frame-shiftENST00000220592ENST00000521059AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000220592ENST00000521059AGO2chr8

141645584

-PTK2chr8

141669777

-
Frame-shiftENST00000220592ENST00000522684AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000220592ENST00000522684AGO2chr8

141645584

-PTK2chr8

141669777

-
Frame-shiftENST00000220592ENST00000535192AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000220592ENST00000538769AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000519980ENST00000340930AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000519980ENST00000340930AGO2chr8

141645584

-PTK2chr8

141669777

-
Frame-shiftENST00000519980ENST00000395218AGO2chr8

141645584

-PTK2chr8

141678523

-
Frame-shiftENST00000519980ENST00000395218AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000519980ENST00000395218AGO2chr8

141645584

-PTK2chr8

141669777

-
Frame-shiftENST00000519980ENST00000430260AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000519980ENST00000430260AGO2chr8

141645584

-PTK2chr8

141669777

-
Frame-shiftENST00000519980ENST00000517887AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000519980ENST00000517887AGO2chr8

141645584

-PTK2chr8

141669777

-
Frame-shiftENST00000519980ENST00000519419AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000519980ENST00000519419AGO2chr8

141645584

-PTK2chr8

141669777

-
Frame-shiftENST00000519980ENST00000519465AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000519980ENST00000519465AGO2chr8

141645584

-PTK2chr8

141669777

-
Frame-shiftENST00000519980ENST00000521059AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000519980ENST00000521059AGO2chr8

141645584

-PTK2chr8

141669777

-
Frame-shiftENST00000519980ENST00000522684AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000519980ENST00000522684AGO2chr8

141645584

-PTK2chr8

141669777

-
Frame-shiftENST00000519980ENST00000535192AGO2chr8

141645584

-PTK2chr8

141684503

-
Frame-shiftENST00000519980ENST00000538769AGO2chr8

141645584

-PTK2chr8

141684503

-
In-frameENST00000220592ENST00000340930AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000220592ENST00000340930AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000220592ENST00000340930AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000220592ENST00000340930AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000220592ENST00000395218AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000220592ENST00000395218AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000220592ENST00000395218AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000220592ENST00000430260AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000220592ENST00000430260AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000220592ENST00000430260AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000220592ENST00000517887AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000220592ENST00000517887AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000220592ENST00000517887AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000220592ENST00000517887AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000220592ENST00000519419AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000220592ENST00000519419AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000220592ENST00000519419AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000220592ENST00000519419AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000220592ENST00000519465AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000220592ENST00000519465AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000220592ENST00000519465AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000220592ENST00000519465AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000220592ENST00000521059AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000220592ENST00000521059AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000220592ENST00000521059AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000220592ENST00000521059AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000220592ENST00000522684AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000220592ENST00000522684AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000220592ENST00000522684AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000220592ENST00000522684AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000220592ENST00000522684AGO2chr8

141645584

-PTK2chr8

141712806

-
In-frameENST00000220592ENST00000535192AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000220592ENST00000535192AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000220592ENST00000535192AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000220592ENST00000535192AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000220592ENST00000535192AGO2chr8

141645584

-PTK2chr8

141669777

-
In-frameENST00000220592ENST00000538769AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000220592ENST00000538769AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000220592ENST00000538769AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000220592ENST00000538769AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000220592ENST00000538769AGO2chr8

141645584

-PTK2chr8

141669777

-
In-frameENST00000519980ENST00000340930AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000519980ENST00000340930AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000519980ENST00000340930AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000519980ENST00000340930AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000519980ENST00000395218AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000519980ENST00000395218AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000519980ENST00000395218AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000519980ENST00000430260AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000519980ENST00000430260AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000519980ENST00000430260AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000519980ENST00000517887AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000519980ENST00000517887AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000519980ENST00000517887AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000519980ENST00000517887AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000519980ENST00000519419AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000519980ENST00000519419AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000519980ENST00000519419AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000519980ENST00000519419AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000519980ENST00000519465AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000519980ENST00000519465AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000519980ENST00000519465AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000519980ENST00000519465AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000519980ENST00000521059AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000519980ENST00000521059AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000519980ENST00000521059AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000519980ENST00000521059AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000519980ENST00000522684AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000519980ENST00000522684AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000519980ENST00000522684AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000519980ENST00000522684AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000519980ENST00000522684AGO2chr8

141645584

-PTK2chr8

141712806

-
In-frameENST00000519980ENST00000535192AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000519980ENST00000535192AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000519980ENST00000535192AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000519980ENST00000535192AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000519980ENST00000535192AGO2chr8

141645584

-PTK2chr8

141669777

-
In-frameENST00000519980ENST00000538769AGO2chr8

141645584

-PTK2chr8

141678523

-
In-frameENST00000519980ENST00000538769AGO2chr8

141645584

-PTK2chr8

141685598

-
In-frameENST00000519980ENST00000538769AGO2chr8

141645584

-PTK2chr8

141675096

-
In-frameENST00000519980ENST00000538769AGO2chr8

141645584

-PTK2chr8

141762415

-
In-frameENST00000519980ENST00000538769AGO2chr8

141645584

-PTK2chr8

141669777

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000220592AGO2chr8141645584-ENST00000522684PTK2chr8141762415-35281351471961604
ENST00000220592AGO2chr8141645584-ENST00000535192PTK2chr8141762415-28991351471823558
ENST00000220592AGO2chr8141645584-ENST00000519465PTK2chr8141762415-30261351471961604
ENST00000220592AGO2chr8141645584-ENST00000517887PTK2chr8141762415-30261351471961604
ENST00000220592AGO2chr8141645584-ENST00000521059PTK2chr8141762415-30261351471961604
ENST00000220592AGO2chr8141645584-ENST00000395218PTK2chr8141762415-30651351472000617
ENST00000220592AGO2chr8141645584-ENST00000538769PTK2chr8141762415-30231351471961604
ENST00000220592AGO2chr8141645584-ENST00000340930PTK2chr8141762415-30621351472000617
ENST00000220592AGO2chr8141645584-ENST00000519419PTK2chr8141762415-27981351471961604
ENST00000519980AGO2chr8141645584-ENST00000522684PTK2chr8141762415-345562741888604
ENST00000519980AGO2chr8141645584-ENST00000535192PTK2chr8141762415-282662741750558
ENST00000519980AGO2chr8141645584-ENST00000519465PTK2chr8141762415-295362741888604
ENST00000519980AGO2chr8141645584-ENST00000517887PTK2chr8141762415-295362741888604
ENST00000519980AGO2chr8141645584-ENST00000521059PTK2chr8141762415-295362741888604
ENST00000519980AGO2chr8141645584-ENST00000395218PTK2chr8141762415-299262741927617
ENST00000519980AGO2chr8141645584-ENST00000538769PTK2chr8141762415-295062741888604
ENST00000519980AGO2chr8141645584-ENST00000340930PTK2chr8141762415-298962741927617
ENST00000519980AGO2chr8141645584-ENST00000519419PTK2chr8141762415-272562741888604

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000220592ENST00000522684AGO2chr8141645584-PTK2chr8141762415-0.0009775650.9990225
ENST00000220592ENST00000535192AGO2chr8141645584-PTK2chr8141762415-0.0007037080.9992963
ENST00000220592ENST00000519465AGO2chr8141645584-PTK2chr8141762415-0.0010529190.9989471
ENST00000220592ENST00000517887AGO2chr8141645584-PTK2chr8141762415-0.0010529190.9989471
ENST00000220592ENST00000521059AGO2chr8141645584-PTK2chr8141762415-0.0010529190.9989471
ENST00000220592ENST00000395218AGO2chr8141645584-PTK2chr8141762415-0.0008857990.9991142
ENST00000220592ENST00000538769AGO2chr8141645584-PTK2chr8141762415-0.0010662680.99893373
ENST00000220592ENST00000340930AGO2chr8141645584-PTK2chr8141762415-0.0009492790.9990507
ENST00000220592ENST00000519419AGO2chr8141645584-PTK2chr8141762415-0.0020525640.9979474
ENST00000519980ENST00000522684AGO2chr8141645584-PTK2chr8141762415-0.0008944050.9991055
ENST00000519980ENST00000535192AGO2chr8141645584-PTK2chr8141762415-0.0006190560.99938095
ENST00000519980ENST00000519465AGO2chr8141645584-PTK2chr8141762415-0.0009556840.99904424
ENST00000519980ENST00000517887AGO2chr8141645584-PTK2chr8141762415-0.0009556840.99904424
ENST00000519980ENST00000521059AGO2chr8141645584-PTK2chr8141762415-0.0009556840.99904424
ENST00000519980ENST00000395218AGO2chr8141645584-PTK2chr8141762415-0.0007952760.9992047
ENST00000519980ENST00000538769AGO2chr8141645584-PTK2chr8141762415-0.0009705790.9990294
ENST00000519980ENST00000340930AGO2chr8141645584-PTK2chr8141762415-0.0008614350.9991386
ENST00000519980ENST00000519419AGO2chr8141645584-PTK2chr8141762415-0.0018304070.99816954

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Fusion Genomic Features for EIF2C2-PTK2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for EIF2C2-PTK2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:141645584/:141685598)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePTK2chr8:141645584chr8:141685598ENST000003409302633863_9138541066.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141685598ENST000005210592632863_9138541053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141685598ENST000005226842632863_9138541053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141712806ENST000003409302333863_9137431066.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141712806ENST000005210592332863_9137431053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141712806ENST000005226842332863_9137431053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141762415ENST000003409301533712_7334441066.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141762415ENST000003409301533863_9134441066.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141762415ENST000005210591532712_7334441053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141762415ENST000005210591532863_9134441053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141762415ENST000005226841532712_7334441053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141762415ENST000005226841532863_9134441053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141762415ENST000003409301533500_5024441066.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141762415ENST000005210591532500_5024441053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141762415ENST000005226841532500_5024441053.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAGO2chr8:141645584chr8:141669777ENST00000220592-119235_3487860.0DomainPAZ
HgeneAGO2chr8:141645584chr8:141669777ENST00000220592-119517_8187860.0DomainPiwi
HgeneAGO2chr8:141645584chr8:141669777ENST00000519980-118235_3487826.0DomainPAZ
HgeneAGO2chr8:141645584chr8:141669777ENST00000519980-118517_8187826.0DomainPiwi
HgeneAGO2chr8:141645584chr8:141675096ENST00000220592-119235_3487860.0DomainPAZ
HgeneAGO2chr8:141645584chr8:141675096ENST00000220592-119517_8187860.0DomainPiwi
HgeneAGO2chr8:141645584chr8:141675096ENST00000519980-118235_3487826.0DomainPAZ
HgeneAGO2chr8:141645584chr8:141675096ENST00000519980-118517_8187826.0DomainPiwi
HgeneAGO2chr8:141645584chr8:141678523ENST00000220592-119235_3487860.0DomainPAZ
HgeneAGO2chr8:141645584chr8:141678523ENST00000220592-119517_8187860.0DomainPiwi
HgeneAGO2chr8:141645584chr8:141678523ENST00000519980-118235_3487826.0DomainPAZ
HgeneAGO2chr8:141645584chr8:141678523ENST00000519980-118517_8187826.0DomainPiwi
HgeneAGO2chr8:141645584chr8:141685598ENST00000220592-119235_3487860.0DomainPAZ
HgeneAGO2chr8:141645584chr8:141685598ENST00000220592-119517_8187860.0DomainPiwi
HgeneAGO2chr8:141645584chr8:141685598ENST00000519980-118235_3487826.0DomainPAZ
HgeneAGO2chr8:141645584chr8:141685598ENST00000519980-118517_8187826.0DomainPiwi
HgeneAGO2chr8:141645584chr8:141712806ENST00000220592-119235_3487860.0DomainPAZ
HgeneAGO2chr8:141645584chr8:141712806ENST00000220592-119517_8187860.0DomainPiwi
HgeneAGO2chr8:141645584chr8:141712806ENST00000519980-118235_3487826.0DomainPAZ
HgeneAGO2chr8:141645584chr8:141712806ENST00000519980-118517_8187826.0DomainPiwi
HgeneAGO2chr8:141645584chr8:141762415ENST00000220592-119235_3487860.0DomainPAZ
HgeneAGO2chr8:141645584chr8:141762415ENST00000220592-119517_8187860.0DomainPiwi
HgeneAGO2chr8:141645584chr8:141762415ENST00000519980-118235_3487826.0DomainPAZ
HgeneAGO2chr8:141645584chr8:141762415ENST00000519980-118517_8187826.0DomainPiwi
TgenePTK2chr8:141645584chr8:141669777ENST000003409303133712_7339951066.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141669777ENST000003409303133863_9139951066.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141669777ENST000005210593032712_7339821053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141669777ENST000005210593032863_9139821053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141669777ENST000005226843032712_7339821053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141669777ENST000005226843032863_9139821053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141675096ENST000003409303033712_7339681066.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141675096ENST000003409303033863_9139681066.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141675096ENST000005210592932712_7339551053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141675096ENST000005210592932863_9139551053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141675096ENST000005226842932712_7339551053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141675096ENST000005226842932863_9139551053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141678523ENST000003409302933712_7339161066.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141678523ENST000003409302933863_9139161066.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141678523ENST000005210592832712_7339031053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141678523ENST000005210592832863_9139031053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141678523ENST000005226842832712_7339031053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141678523ENST000005226842832863_9139031053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141685598ENST000003409302633712_7338541066.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141685598ENST000005210592632712_7338541053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141685598ENST000005226842632712_7338541053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141712806ENST000003409302333712_7337431066.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141712806ENST000005210592332712_7337431053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141712806ENST000005226842332712_7337431053.0Compositional biasNote=Pro-rich
TgenePTK2chr8:141645584chr8:141669777ENST00000340930313335_3559951066.0DomainFERM
TgenePTK2chr8:141645584chr8:141669777ENST000003409303133422_6809951066.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141669777ENST00000521059303235_3559821053.0DomainFERM
TgenePTK2chr8:141645584chr8:141669777ENST000005210593032422_6809821053.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141669777ENST00000522684303235_3559821053.0DomainFERM
TgenePTK2chr8:141645584chr8:141669777ENST000005226843032422_6809821053.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141675096ENST00000340930303335_3559681066.0DomainFERM
TgenePTK2chr8:141645584chr8:141675096ENST000003409303033422_6809681066.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141675096ENST00000521059293235_3559551053.0DomainFERM
TgenePTK2chr8:141645584chr8:141675096ENST000005210592932422_6809551053.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141675096ENST00000522684293235_3559551053.0DomainFERM
TgenePTK2chr8:141645584chr8:141675096ENST000005226842932422_6809551053.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141678523ENST00000340930293335_3559161066.0DomainFERM
TgenePTK2chr8:141645584chr8:141678523ENST000003409302933422_6809161066.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141678523ENST00000521059283235_3559031053.0DomainFERM
TgenePTK2chr8:141645584chr8:141678523ENST000005210592832422_6809031053.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141678523ENST00000522684283235_3559031053.0DomainFERM
TgenePTK2chr8:141645584chr8:141678523ENST000005226842832422_6809031053.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141685598ENST00000340930263335_3558541066.0DomainFERM
TgenePTK2chr8:141645584chr8:141685598ENST000003409302633422_6808541066.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141685598ENST00000521059263235_3558541053.0DomainFERM
TgenePTK2chr8:141645584chr8:141685598ENST000005210592632422_6808541053.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141685598ENST00000522684263235_3558541053.0DomainFERM
TgenePTK2chr8:141645584chr8:141685598ENST000005226842632422_6808541053.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141712806ENST00000340930233335_3557431066.0DomainFERM
TgenePTK2chr8:141645584chr8:141712806ENST000003409302333422_6807431066.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141712806ENST00000521059233235_3557431053.0DomainFERM
TgenePTK2chr8:141645584chr8:141712806ENST000005210592332422_6807431053.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141712806ENST00000522684233235_3557431053.0DomainFERM
TgenePTK2chr8:141645584chr8:141712806ENST000005226842332422_6807431053.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141762415ENST00000340930153335_3554441066.0DomainFERM
TgenePTK2chr8:141645584chr8:141762415ENST000003409301533422_6804441066.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141762415ENST00000521059153235_3554441053.0DomainFERM
TgenePTK2chr8:141645584chr8:141762415ENST000005210591532422_6804441053.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141762415ENST00000522684153235_3554441053.0DomainFERM
TgenePTK2chr8:141645584chr8:141762415ENST000005226841532422_6804441053.0DomainProtein kinase
TgenePTK2chr8:141645584chr8:141669777ENST000003409303133428_4349951066.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141669777ENST000003409303133500_5029951066.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141669777ENST000005210593032428_4349821053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141669777ENST000005210593032500_5029821053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141669777ENST000005226843032428_4349821053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141669777ENST000005226843032500_5029821053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141675096ENST000003409303033428_4349681066.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141675096ENST000003409303033500_5029681066.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141675096ENST000005210592932428_4349551053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141675096ENST000005210592932500_5029551053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141675096ENST000005226842932428_4349551053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141675096ENST000005226842932500_5029551053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141678523ENST000003409302933428_4349161066.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141678523ENST000003409302933500_5029161066.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141678523ENST000005210592832428_4349031053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141678523ENST000005210592832500_5029031053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141678523ENST000005226842832428_4349031053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141678523ENST000005226842832500_5029031053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141685598ENST000003409302633428_4348541066.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141685598ENST000003409302633500_5028541066.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141685598ENST000005210592632428_4348541053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141685598ENST000005210592632500_5028541053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141685598ENST000005226842632428_4348541053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141685598ENST000005226842632500_5028541053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141712806ENST000003409302333428_4347431066.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141712806ENST000003409302333500_5027431066.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141712806ENST000005210592332428_4347431053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141712806ENST000005210592332500_5027431053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141712806ENST000005226842332428_4347431053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141712806ENST000005226842332500_5027431053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141762415ENST000003409301533428_4344441066.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141762415ENST000005210591532428_4344441053.0Nucleotide bindingATP
TgenePTK2chr8:141645584chr8:141762415ENST000005226841532428_4344441053.0Nucleotide bindingATP


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Fusion Gene Sequence for EIF2C2-PTK2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>2913_2913_1_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000340930_length(transcript)=3062nt_BP=135nt
GGCCGCGCCGGGGCGGATCGTGCGGCCGGCGGCTCCCTCGCGGCTCGCGGCGTCGGGGCCCGTGGCGCGCGCGCGGCCGCCCCTCGGCCC
CGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTAAAACATGTAAAAACTGT
ACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTGTGAAGCTGATTGGAGTC
ATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAAGGAAATACAGTTTGGAT
CTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTACACAGGGACATTGCTGCT
CGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATAGTACTTACTACAAAGCT
TCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTGACGTATGGATGTTTGGT
GTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTCGAATTGAAAATGGGGAA
AGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCAGCAGGCGGCCCAGGTTT
ACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGGAGTCCAGAAGACAGGCC
ACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGAGGTCCAGCGAAGGATTT
TATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGTTTCTGGCTACCCTGGTTCACATGGAATCACAGCCATGGCTGGCAGC
ATCTATCCAGGTCAGGCATCTCTTTTGGACCAAACAGATTCATGGAATCATAGACCTCAGGAGATAGCAATGTGGCAGCCCAATGTGGAG
GACTCTACAGTATTGGACCTGCGAGGGATTGGGCAAGTGTTGCCAACCCATCTGATGGAAGAGCGTCTAATCCGACAGCAACAGGAAATG
GAAGAAGATCAGCGCTGGCTGGAAAAAGAGGAAAGATTTCTGAAACCTGATGTGAGACTCTCTCGAGGCAGTATTGACAGGGAGGATGGA
AGTCTTCAGGGTCCGATTGGAAACCAACATATATATCAGCCTGTGGGTAAACCAGGTAAAGAAGAAAAGAATTGGGCGGAAAGAAATCCT
GCAGCTCCACCAAAGAAACCGCCTCGCCCTGGAGCTCCCGGTCATCTGGGAAGCCTTGCCAGCCTCAGCAGCCCTGCTGACAGCTACAAC
GAGGGTGTCAAGCCATGGAGGCTTCAGCCCCAGGAAATCAGCCCCCCTCCTACTGCCAACCTGGACCGGTCGAATGATAAGGTGTACGAG
AATGTGACGGGCCTGGTGAAAGCTGTCATCGAGATGTCCAGTAAAATCCAGCCAGCCCCACCAGAGGAGTATGTCCCTATGGTGAAGGAA
GTCGGCTTGGCCCTGAGGACATTATTGGCCACTGTGGATGAGACCATTCCCCTCCTACCAGCCAGCACCCACCGAGAGATTGAGATGGCA
CAGAAGCTATTGAACTCTGACCTGGGTGAGCTCATCAACAAGATGAAACTGGCCCAGCAGTATGTCATGACCAGCCTCCAGCAAGAGTAC
AAAAAGCAAATGCTGACTGCTGCTCACGCCCTGGCTGTGGATGCCAAAAACTTACTCGATGTCATTGACCAAGCAAGACTGAAAATGCTT
GGGCAGACGAGACCACACTGAGCCTCCCCTAGGAGCACGTCTTGCTACCCTCTTTTGAAGATGTTCTCTAGCCTTCCACCAGCAGCGAGG
AATTAACCCTGTGTCCTCAGTCGCCAGCACTTACAGCTCCAACTTTTTTGAATGACCATCTGGTTGAAAAATCTTTCTCATATAAGTTTA
ACCACACTTTGATTTGGGTTCATTTTTTGTTTTGTTTTTTTCAATCATGATATTCAGAAAAATCCAGGATCCAAAATGTGGCGTTTTTCT
AAGAATGAAAATTATATGTAAGCTTTTAAGCATCATGAAGAACAATTTATGTTCACATTAAGATACGTTCTAAAGGGGGATGGCCAAGGG
GTGACATCTTAATTCCTAAACTACCTTAGCTGCATAGTGGAAGAGGAGAGCATGAAGCAAAGAATTCCAGGAAACCCAAGAGGCTGAGAA
TTCTTTTGTCTACCATAGAATTATTATCCAGACTGGAATTTTTGTTTGTTAGAACACCCTTCAGTTGCAATATGCTAATCCCACTTTACA
AAGAATATAAAAGCTATATTTTGAAGACTTGAGTTATTTCAGAAAAAACTACAGCCCTTTTTGTCTTACCTGCCTTTTACTTTCGTGTGG
ATATGTGAAGCATTGGGTCGGGAACTAGCTGTAGAACACAACTAAAAACTCATGTCTTTTTTCACAGAATAATGTGCCAGTTTTTTGTAG
CAATGTTATTTCTCTTGGAAGCAGAAATGCTTTGTACCAGAGCACCTCCAAACTGCATTGAGGAGAAGTTCCAGAACCATCCCCTTTTTC
CATTTTTATATAATTTATAAAGAAAGATTAAAGCCATGTTGACTATTTTACAGCCACTGGAGTTAACTAACCCTTCCTTGTATCTGTCTT
CCCAGGAGAGAATGAAGCAAAACAGGAATTTGGTTTTCTTTTGATGTCCAGTTACACCATCCATTCTGTTAATTTTGAAAAAATATACCC
TCCCTTTAGTTTGTTGGGGGATATAAATTATTCTCAGGAAGAATATAATGAACTGTACAGTTACTTTGACCTATTAAAAAGGTGTTACCA

>2913_2913_1_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000340930_length(amino acids)=617AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLM
EERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPGKEEKNWAERNPAAPPKKPPRPGAPGHLGSL
ASLSSPADSYNEGVKPWRLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLL

--------------------------------------------------------------
>2913_2913_2_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000395218_length(transcript)=3065nt_BP=135nt
GGCCGCGCCGGGGCGGATCGTGCGGCCGGCGGCTCCCTCGCGGCTCGCGGCGTCGGGGCCCGTGGCGCGCGCGCGGCCGCCCCTCGGCCC
CGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTAAAACATGTAAAAACTGT
ACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTGTGAAGCTGATTGGAGTC
ATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAAGGAAATACAGTTTGGAT
CTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTACACAGGGACATTGCTGCT
CGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATAGTACTTACTACAAAGCT
TCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTGACGTATGGATGTTTGGT
GTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTCGAATTGAAAATGGGGAA
AGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCAGCAGGCGGCCCAGGTTT
ACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGGAGTCCAGAAGACAGGCC
ACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGAGGTCCAGCGAAGGATTT
TATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGTTTCTGGCTACCCTGGTTCACATGGAATCACAGCCATGGCTGGCAGC
ATCTATCCAGGTCAGGCATCTCTTTTGGACCAAACAGATTCATGGAATCATAGACCTCAGGAGATAGCAATGTGGCAGCCCAATGTGGAG
GACTCTACAGTATTGGACCTGCGAGGGATTGGGCAAGTGTTGCCAACCCATCTGATGGAAGAGCGTCTAATCCGACAGCAACAGGAAATG
GAAGAAGATCAGCGCTGGCTGGAAAAAGAGGAAAGATTTCTGAAACCTGATGTGAGACTCTCTCGAGGCAGTATTGACAGGGAGGATGGA
AGTCTTCAGGGTCCGATTGGAAACCAACATATATATCAGCCTGTGGGTAAACCAGGTAAAGAAGAAAAGAATTGGGCGGAAAGAAATCCT
GCAGCTCCACCAAAGAAACCGCCTCGCCCTGGAGCTCCCGGTCATCTGGGAAGCCTTGCCAGCCTCAGCAGCCCTGCTGACAGCTACAAC
GAGGGTGTCAAGCCAAATCAGCTTCAGCCCCAGGAAATCAGCCCCCCTCCTACTGCCAACCTGGACCGGTCGAATGATAAGGTGTACGAG
AATGTGACGGGCCTGGTGAAAGCTGTCATCGAGATGTCCAGTAAAATCCAGCCAGCCCCACCAGAGGAGTATGTCCCTATGGTGAAGGAA
GTCGGCTTGGCCCTGAGGACATTATTGGCCACTGTGGATGAGACCATTCCCCTCCTACCAGCCAGCACCCACCGAGAGATTGAGATGGCA
CAGAAGCTATTGAACTCTGACCTGGGTGAGCTCATCAACAAGATGAAACTGGCCCAGCAGTATGTCATGACCAGCCTCCAGCAAGAGTAC
AAAAAGCAAATGCTGACTGCTGCTCACGCCCTGGCTGTGGATGCCAAAAACTTACTCGATGTCATTGACCAAGCAAGACTGAAAATGCTT
GGGCAGACGAGACCACACTGAGCCTCCCCTAGGAGCACGTCTTGCTACCCTCTTTTGAAGATGTTCTCTAGCCTTCCACCAGCAGCGAGG
AATTAACCCTGTGTCCTCAGTCGCCAGCACTTACAGCTCCAACTTTTTTGAATGACCATCTGGTTGAAAAATCTTTCTCATATAAGTTTA
ACCACACTTTGATTTGGGTTCATTTTTTGTTTTGTTTTTTTCAATCATGATATTCAGAAAAATCCAGGATCCAAAATGTGGCGTTTTTCT
AAGAATGAAAATTATATGTAAGCTTTTAAGCATCATGAAGAACAATTTATGTTCACATTAAGATACGTTCTAAAGGGGGATGGCCAAGGG
GTGACATCTTAATTCCTAAACTACCTTAGCTGCATAGTGGAAGAGGAGAGCATGAAGCAAAGAATTCCAGGAAACCCAAGAGGCTGAGAA
TTCTTTTGTCTACCATAGAATTATTATCCAGACTGGAATTTTTGTTTGTTAGAACACCCTTCAGTTGCAATATGCTAATCCCACTTTACA
AAGAATATAAAAGCTATATTTTGAAGACTTGAGTTATTTCAGAAAAAACTACAGCCCTTTTTGTCTTACCTGCCTTTTACTTTCGTGTGG
ATATGTGAAGCATTGGGTCGGGAACTAGCTGTAGAACACAACTAAAAACTCATGTCTTTTTTCACAGAATAATGTGCCAGTTTTTTGTAG
CAATGTTATTTCTCTTGGAAGCAGAAATGCTTTGTACCAGAGCACCTCCAAACTGCATTGAGGAGAAGTTCCAGAACCATCCCCTTTTTC
CATTTTTATATAATTTATAAAGAAAGATTAAAGCCATGTTGACTATTTTACAGCCACTGGAGTTAACTAACCCTTCCTTGTATCTGTCTT
CCCAGGAGAGAATGAAGCAAAACAGGAATTTGGTTTTCTTTTGATGTCCAGTTACACCATCCATTCTGTTAATTTTGAAAAAATATACCC
TCCCTTTAGTTTGTTGGGGGATATAAATTATTCTCAGGAAGAATATAATGAACTGTACAGTTACTTTGACCTATTAAAAAGGTGTTACCA

>2913_2913_2_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000395218_length(amino acids)=617AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLM
EERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPGKEEKNWAERNPAAPPKKPPRPGAPGHLGSL
ASLSSPADSYNEGVKPNQLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLL

--------------------------------------------------------------
>2913_2913_3_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000517887_length(transcript)=3026nt_BP=135nt
GGCCGCGCCGGGGCGGATCGTGCGGCCGGCGGCTCCCTCGCGGCTCGCGGCGTCGGGGCCCGTGGCGCGCGCGCGGCCGCCCCTCGGCCC
CGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTAAAACATGTAAAAACTGT
ACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTGTGAAGCTGATTGGAGTC
ATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAAGGAAATACAGTTTGGAT
CTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTACACAGGGACATTGCTGCT
CGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATAGTACTTACTACAAAGCT
TCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTGACGTATGGATGTTTGGT
GTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTCGAATTGAAAATGGGGAA
AGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCAGCAGGCGGCCCAGGTTT
ACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGGAGTCCAGAAGACAGGCC
ACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGAGGTCCAGCGAAGGATTT
TATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGTTTCTGGCTACCCTGGTTCACATGGAATCACAGCCATGGCTGGCAGC
ATCTATCCAGGTCAGGCATCTCTTTTGGACCAAACAGATTCATGGAATCATAGACCTCAGGAGATAGCAATGTGGCAGCCCAATGTGGAG
GACTCTACAGTATTGGACCTGCGAGGGATTGGGCAAGTGTTGCCAACCCATCTGATGGAAGAGCGTCTAATCCGACAGCAACAGGAAATG
GAAGAAGATCAGCGCTGGCTGGAAAAAGAGGAAAGATTTCTGAAACCTGATGTGAGACTCTCTCGAGGCAGTATTGACAGGGAGGATGGA
AGTCTTCAGGGTCCGATTGGAAACCAACATATATATCAGCCTGTGGGTAAACCAGATCCTGCAGCTCCACCAAAGAAACCGCCTCGCCCT
GGAGCTCCCGGTCATCTGGGAAGCCTTGCCAGCCTCAGCAGCCCTGCTGACAGCTACAACGAGGGTGTCAAGCTTCAGCCCCAGGAAATC
AGCCCCCCTCCTACTGCCAACCTGGACCGGTCGAATGATAAGGTGTACGAGAATGTGACGGGCCTGGTGAAAGCTGTCATCGAGATGTCC
AGTAAAATCCAGCCAGCCCCACCAGAGGAGTATGTCCCTATGGTGAAGGAAGTCGGCTTGGCCCTGAGGACATTATTGGCCACTGTGGAT
GAGACCATTCCCCTCCTACCAGCCAGCACCCACCGAGAGATTGAGATGGCACAGAAGCTATTGAACTCTGACCTGGGTGAGCTCATCAAC
AAGATGAAACTGGCCCAGCAGTATGTCATGACCAGCCTCCAGCAAGAGTACAAAAAGCAAATGCTGACTGCTGCTCACGCCCTGGCTGTG
GATGCCAAAAACTTACTCGATGTCATTGACCAAGCAAGACTGAAAATGCTTGGGCAGACGAGACCACACTGAGCCTCCCCTAGGAGCACG
TCTTGCTACCCTCTTTTGAAGATGTTCTCTAGCCTTCCACCAGCAGCGAGGAATTAACCCTGTGTCCTCAGTCGCCAGCACTTACAGCTC
CAACTTTTTTGAATGACCATCTGGTTGAAAAATCTTTCTCATATAAGTTTAACCACACTTTGATTTGGGTTCATTTTTTGTTTTGTTTTT
TTCAATCATGATATTCAGAAAAATCCAGGATCCAAAATGTGGCGTTTTTCTAAGAATGAAAATTATATGTAAGCTTTTAAGCATCATGAA
GAACAATTTATGTTCACATTAAGATACGTTCTAAAGGGGGATGGCCAAGGGGTGACATCTTAATTCCTAAACTACCTTAGCTGCATAGTG
GAAGAGGAGAGCATGAAGCAAAGAATTCCAGGAAACCCAAGAGGCTGAGAATTCTTTTGTCTACCATAGAATTATTATCCAGACTGGAAT
TTTTGTTTGTTAGAACACCCTTCAGTTGCAATATGCTAATCCCACTTTACAAAGAATATAAAAGCTATATTTTGAAGACTTGAGTTATTT
CAGAAAAAACTACAGCCCTTTTTGTCTTACCTGCCTTTTACTTTCGTGTGGATATGTGAAGCATTGGGTCGGGAACTAGCTGTAGAACAC
AACTAAAAACTCATGTCTTTTTTCACAGAATAATGTGCCAGTTTTTTGTAGCAATGTTATTTCTCTTGGAAGCAGAAATGCTTTGTACCA
GAGCACCTCCAAACTGCATTGAGGAGAAGTTCCAGAACCATCCCCTTTTTCCATTTTTATATAATTTATAAAGAAAGATTAAAGCCATGT
TGACTATTTTACAGCCACTGGAGTTAACTAACCCTTCCTTGTATCTGTCTTCCCAGGAGAGAATGAAGCAAAACAGGAATTTGGTTTTCT
TTTGATGTCCAGTTACACCATCCATTCTGTTAATTTTGAAAAAATATACCCTCCCTTTAGTTTGTTGGGGGATATAAATTATTCTCAGGA

>2913_2913_3_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000517887_length(amino acids)=604AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLM
EERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSY
NEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQK

--------------------------------------------------------------
>2913_2913_4_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000519419_length(transcript)=2798nt_BP=135nt
GGCCGCGCCGGGGCGGATCGTGCGGCCGGCGGCTCCCTCGCGGCTCGCGGCGTCGGGGCCCGTGGCGCGCGCGCGGCCGCCCCTCGGCCC
CGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTAAAACATGTAAAAACTGT
ACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTGTGAAGCTGATTGGAGTC
ATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAAGGAAATACAGTTTGGAT
CTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTACACAGGGACATTGCTGCT
CGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATAGTACTTACTACAAAGCT
TCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTGACGTATGGATGTTTGGT
GTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTCGAATTGAAAATGGGGAA
AGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCAGCAGGCGGCCCAGGTTT
ACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGGAGTCCAGAAGACAGGCC
ACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGAGGTCCAGCGAAGGATTT
TATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGTTTCTGGCTACCCTGGTTCACATGGAATCACAGCCATGGCTGGCAGC
ATCTATCCAGGTCAGGCATCTCTTTTGGACCAAACAGATTCATGGAATCATAGACCTCAGGAGATAGCAATGTGGCAGCCCAATGTGGAG
GACTCTACAGTATTGGACCTGCGAGGGATTGGGCAAGTGTTGCCAACCCATCTGATGGAAGAGCGTCTAATCCGACAGCAACAGGAAATG
GAAGAAGATCAGCGCTGGCTGGAAAAAGAGGAAAGATTTCTGAAACCTGATGTGAGACTCTCTCGAGGCAGTATTGACAGGGAGGATGGA
AGTCTTCAGGGTCCGATTGGAAACCAACATATATATCAGCCTGTGGGTAAACCAGATCCTGCAGCTCCACCAAAGAAACCGCCTCGCCCT
GGAGCTCCCGGTCATCTGGGAAGCCTTGCCAGCCTCAGCAGCCCTGCTGACAGCTACAACGAGGGTGTCAAGCTTCAGCCCCAGGAAATC
AGCCCCCCTCCTACTGCCAACCTGGACCGGTCGAATGATAAGGTGTACGAGAATGTGACGGGCCTGGTGAAAGCTGTCATCGAGATGTCC
AGTAAAATCCAGCCAGCCCCACCAGAGGAGTATGTCCCTATGGTGAAGGAAGTCGGCTTGGCCCTGAGGACATTATTGGCCACTGTGGAT
GAGACCATTCCCCTCCTACCAGCCAGCACCCACCGAGAGATTGAGATGGCACAGAAGCTATTGAACTCTGACCTGGGTGAGCTCATCAAC
AAGATGAAACTGGCCCAGCAGTATGTCATGACCAGCCTCCAGCAAGAGTACAAAAAGCAAATGCTGACTGCTGCTCACGCCCTGGCTGTG
GATGCCAAAAACTTACTCGATGTCATTGACCAAGCAAGACTGAAAATGCTTGGGCAGACGAGACCACACTGAGCCTCCCCTAGGAGCACG
TCTTGCTACCCTCTTTTGAAGATGTTCTCTAGCCTTCCACCAGCAGCGAGGAATTAACCCTGTGTCCTCAGTCGCCAGCACTTACAGCTC
CAACTTTTTTGAATGACCATCTGGTTGAAAAATCTTTCTCATATAAGTTTAACCACACTTTGATTTGGGTTCATTTTTTGTTTTGTTTTT
TTCAATCATGATATTCAGAAAAATCCAGGATCCAAAATGTGGCGTTTTTCTAAGAATGAAAATTATATGTAAGCTTTTAAGCATCATGAA
GAACAATTTATGTTCACATTAAGATACGTTCTAAAGGGGGATGGCCAAGGGGTGACATCTTAATTCCTAAACTACCTTAGCTGCATAGTG
GAAGAGGAGAGCATGAAGCAAAGAATTCCAGGAAACCCAAGAGGCTGAGAATTCTTTTGTCTACCATAGAATTATTATCCAGACTGGAAT
TTTTGTTTGTTAGAACACCCTTCAGTTGCAATATGCTAATCCCACTTTACAAAGAATATAAAAGCTATATTTTGAAGACTTGAGTTATTT
CAGAAAAAACTACAGCCCTTTTTGTCTTACCTGCCTTTTACTTTCGTGTGGATATGTGAAGCATTGGGTCGGGAACTAGCTGTAGAACAC
AACTAAAAACTCATGTCTTTTTTCACAGAATAATGTGCCAGTTTTTTGTAGCAATGTTATTTCTCTTGGAAGCAGAAATGCTTTGTACCA
GAGCACCTCCAAACTGCATTGAGGAGAAGTTCCAGAACCATCCCCTTTTTCCATTTTTATATAATTTATAAAGAAAGATTAAAGCCATGT

>2913_2913_4_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000519419_length(amino acids)=604AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLM
EERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSY
NEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQK

--------------------------------------------------------------
>2913_2913_5_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000519465_length(transcript)=3026nt_BP=135nt
GGCCGCGCCGGGGCGGATCGTGCGGCCGGCGGCTCCCTCGCGGCTCGCGGCGTCGGGGCCCGTGGCGCGCGCGCGGCCGCCCCTCGGCCC
CGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTAAAACATGTAAAAACTGT
ACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTGTGAAGCTGATTGGAGTC
ATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAAGGAAATACAGTTTGGAT
CTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTACACAGGGACATTGCTGCT
CGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATAGTACTTACTACAAAGCT
TCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTGACGTATGGATGTTTGGT
GTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTCGAATTGAAAATGGGGAA
AGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCAGCAGGCGGCCCAGGTTT
ACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGGAGTCCAGAAGACAGGCC
ACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGAGGTCCAGCGAAGGATTT
TATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGTTTCTGGCTACCCTGGTTCACATGGAATCACAGCCATGGCTGGCAGC
ATCTATCCAGGTCAGGCATCTCTTTTGGACCAAACAGATTCATGGAATCATAGACCTCAGGAGATAGCAATGTGGCAGCCCAATGTGGAG
GACTCTACAGTATTGGACCTGCGAGGGATTGGGCAAGTGTTGCCAACCCATCTGATGGAAGAGCGTCTAATCCGACAGCAACAGGAAATG
GAAGAAGATCAGCGCTGGCTGGAAAAAGAGGAAAGATTTCTGAAACCTGATGTGAGACTCTCTCGAGGCAGTATTGACAGGGAGGATGGA
AGTCTTCAGGGTCCGATTGGAAACCAACATATATATCAGCCTGTGGGTAAACCAGATCCTGCAGCTCCACCAAAGAAACCGCCTCGCCCT
GGAGCTCCCGGTCATCTGGGAAGCCTTGCCAGCCTCAGCAGCCCTGCTGACAGCTACAACGAGGGTGTCAAGCTTCAGCCCCAGGAAATC
AGCCCCCCTCCTACTGCCAACCTGGACCGGTCGAATGATAAGGTGTACGAGAATGTGACGGGCCTGGTGAAAGCTGTCATCGAGATGTCC
AGTAAAATCCAGCCAGCCCCACCAGAGGAGTATGTCCCTATGGTGAAGGAAGTCGGCTTGGCCCTGAGGACATTATTGGCCACTGTGGAT
GAGACCATTCCCCTCCTACCAGCCAGCACCCACCGAGAGATTGAGATGGCACAGAAGCTATTGAACTCTGACCTGGGTGAGCTCATCAAC
AAGATGAAACTGGCCCAGCAGTATGTCATGACCAGCCTCCAGCAAGAGTACAAAAAGCAAATGCTGACTGCTGCTCACGCCCTGGCTGTG
GATGCCAAAAACTTACTCGATGTCATTGACCAAGCAAGACTGAAAATGCTTGGGCAGACGAGACCACACTGAGCCTCCCCTAGGAGCACG
TCTTGCTACCCTCTTTTGAAGATGTTCTCTAGCCTTCCACCAGCAGCGAGGAATTAACCCTGTGTCCTCAGTCGCCAGCACTTACAGCTC
CAACTTTTTTGAATGACCATCTGGTTGAAAAATCTTTCTCATATAAGTTTAACCACACTTTGATTTGGGTTCATTTTTTGTTTTGTTTTT
TTCAATCATGATATTCAGAAAAATCCAGGATCCAAAATGTGGCGTTTTTCTAAGAATGAAAATTATATGTAAGCTTTTAAGCATCATGAA
GAACAATTTATGTTCACATTAAGATACGTTCTAAAGGGGGATGGCCAAGGGGTGACATCTTAATTCCTAAACTACCTTAGCTGCATAGTG
GAAGAGGAGAGCATGAAGCAAAGAATTCCAGGAAACCCAAGAGGCTGAGAATTCTTTTGTCTACCATAGAATTATTATCCAGACTGGAAT
TTTTGTTTGTTAGAACACCCTTCAGTTGCAATATGCTAATCCCACTTTACAAAGAATATAAAAGCTATATTTTGAAGACTTGAGTTATTT
CAGAAAAAACTACAGCCCTTTTTGTCTTACCTGCCTTTTACTTTCGTGTGGATATGTGAAGCATTGGGTCGGGAACTAGCTGTAGAACAC
AACTAAAAACTCATGTCTTTTTTCACAGAATAATGTGCCAGTTTTTTGTAGCAATGTTATTTCTCTTGGAAGCAGAAATGCTTTGTACCA
GAGCACCTCCAAACTGCATTGAGGAGAAGTTCCAGAACCATCCCCTTTTTCCATTTTTATATAATTTATAAAGAAAGATTAAAGCCATGT
TGACTATTTTACAGCCACTGGAGTTAACTAACCCTTCCTTGTATCTGTCTTCCCAGGAGAGAATGAAGCAAAACAGGAATTTGGTTTTCT
TTTGATGTCCAGTTACACCATCCATTCTGTTAATTTTGAAAAAATATACCCTCCCTTTAGTTTGTTGGGGGATATAAATTATTCTCAGGA

>2913_2913_5_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000519465_length(amino acids)=604AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLM
EERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSY
NEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQK

--------------------------------------------------------------
>2913_2913_6_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000521059_length(transcript)=3026nt_BP=135nt
GGCCGCGCCGGGGCGGATCGTGCGGCCGGCGGCTCCCTCGCGGCTCGCGGCGTCGGGGCCCGTGGCGCGCGCGCGGCCGCCCCTCGGCCC
CGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTAAAACATGTAAAAACTGT
ACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTGTGAAGCTGATTGGAGTC
ATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAAGGAAATACAGTTTGGAT
CTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTACACAGGGACATTGCTGCT
CGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATAGTACTTACTACAAAGCT
TCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTGACGTATGGATGTTTGGT
GTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTCGAATTGAAAATGGGGAA
AGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCAGCAGGCGGCCCAGGTTT
ACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGGAGTCCAGAAGACAGGCC
ACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGAGGTCCAGCGAAGGATTT
TATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGTTTCTGGCTACCCTGGTTCACATGGAATCACAGCCATGGCTGGCAGC
ATCTATCCAGGTCAGGCATCTCTTTTGGACCAAACAGATTCATGGAATCATAGACCTCAGGAGATAGCAATGTGGCAGCCCAATGTGGAG
GACTCTACAGTATTGGACCTGCGAGGGATTGGGCAAGTGTTGCCAACCCATCTGATGGAAGAGCGTCTAATCCGACAGCAACAGGAAATG
GAAGAAGATCAGCGCTGGCTGGAAAAAGAGGAAAGATTTCTGAAACCTGATGTGAGACTCTCTCGAGGCAGTATTGACAGGGAGGATGGA
AGTCTTCAGGGTCCGATTGGAAACCAACATATATATCAGCCTGTGGGTAAACCAGATCCTGCAGCTCCACCAAAGAAACCGCCTCGCCCT
GGAGCTCCCGGTCATCTGGGAAGCCTTGCCAGCCTCAGCAGCCCTGCTGACAGCTACAACGAGGGTGTCAAGCTTCAGCCCCAGGAAATC
AGCCCCCCTCCTACTGCCAACCTGGACCGGTCGAATGATAAGGTGTACGAGAATGTGACGGGCCTGGTGAAAGCTGTCATCGAGATGTCC
AGTAAAATCCAGCCAGCCCCACCAGAGGAGTATGTCCCTATGGTGAAGGAAGTCGGCTTGGCCCTGAGGACATTATTGGCCACTGTGGAT
GAGACCATTCCCCTCCTACCAGCCAGCACCCACCGAGAGATTGAGATGGCACAGAAGCTATTGAACTCTGACCTGGGTGAGCTCATCAAC
AAGATGAAACTGGCCCAGCAGTATGTCATGACCAGCCTCCAGCAAGAGTACAAAAAGCAAATGCTGACTGCTGCTCACGCCCTGGCTGTG
GATGCCAAAAACTTACTCGATGTCATTGACCAAGCAAGACTGAAAATGCTTGGGCAGACGAGACCACACTGAGCCTCCCCTAGGAGCACG
TCTTGCTACCCTCTTTTGAAGATGTTCTCTAGCCTTCCACCAGCAGCGAGGAATTAACCCTGTGTCCTCAGTCGCCAGCACTTACAGCTC
CAACTTTTTTGAATGACCATCTGGTTGAAAAATCTTTCTCATATAAGTTTAACCACACTTTGATTTGGGTTCATTTTTTGTTTTGTTTTT
TTCAATCATGATATTCAGAAAAATCCAGGATCCAAAATGTGGCGTTTTTCTAAGAATGAAAATTATATGTAAGCTTTTAAGCATCATGAA
GAACAATTTATGTTCACATTAAGATACGTTCTAAAGGGGGATGGCCAAGGGGTGACATCTTAATTCCTAAACTACCTTAGCTGCATAGTG
GAAGAGGAGAGCATGAAGCAAAGAATTCCAGGAAACCCAAGAGGCTGAGAATTCTTTTGTCTACCATAGAATTATTATCCAGACTGGAAT
TTTTGTTTGTTAGAACACCCTTCAGTTGCAATATGCTAATCCCACTTTACAAAGAATATAAAAGCTATATTTTGAAGACTTGAGTTATTT
CAGAAAAAACTACAGCCCTTTTTGTCTTACCTGCCTTTTACTTTCGTGTGGATATGTGAAGCATTGGGTCGGGAACTAGCTGTAGAACAC
AACTAAAAACTCATGTCTTTTTTCACAGAATAATGTGCCAGTTTTTTGTAGCAATGTTATTTCTCTTGGAAGCAGAAATGCTTTGTACCA
GAGCACCTCCAAACTGCATTGAGGAGAAGTTCCAGAACCATCCCCTTTTTCCATTTTTATATAATTTATAAAGAAAGATTAAAGCCATGT
TGACTATTTTACAGCCACTGGAGTTAACTAACCCTTCCTTGTATCTGTCTTCCCAGGAGAGAATGAAGCAAAACAGGAATTTGGTTTTCT
TTTGATGTCCAGTTACACCATCCATTCTGTTAATTTTGAAAAAATATACCCTCCCTTTAGTTTGTTGGGGGATATAAATTATTCTCAGGA

>2913_2913_6_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000521059_length(amino acids)=604AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLM
EERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSY
NEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQK

--------------------------------------------------------------
>2913_2913_7_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000522684_length(transcript)=3528nt_BP=135nt
GGCCGCGCCGGGGCGGATCGTGCGGCCGGCGGCTCCCTCGCGGCTCGCGGCGTCGGGGCCCGTGGCGCGCGCGCGGCCGCCCCTCGGCCC
CGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTAAAACATGTAAAAACTGT
ACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTGTGAAGCTGATTGGAGTC
ATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAAGGAAATACAGTTTGGAT
CTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTACACAGGGACATTGCTGCT
CGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATAGTACTTACTACAAAGCT
TCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTGACGTATGGATGTTTGGT
GTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTCGAATTGAAAATGGGGAA
AGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCAGCAGGCGGCCCAGGTTT
ACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGGAGTCCAGAAGACAGGCC
ACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGAGGTCCAGCGAAGGATTT
TATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGTTTCTGGCTACCCTGGTTCACATGGAATCACAGCCATGGCTGGCAGC
ATCTATCCAGGTCAGGCATCTCTTTTGGACCAAACAGATTCATGGAATCATAGACCTCAGGAGATAGCAATGTGGCAGCCCAATGTGGAG
GACTCTACAGTATTGGACCTGCGAGGGATTGGGCAAGTGTTGCCAACCCATCTGATGGAAGAGCGTCTAATCCGACAGCAACAGGAAATG
GAAGAAGATCAGCGCTGGCTGGAAAAAGAGGAAAGATTTCTGAAACCTGATGTGAGACTCTCTCGAGGCAGTATTGACAGGGAGGATGGA
AGTCTTCAGGGTCCGATTGGAAACCAACATATATATCAGCCTGTGGGTAAACCAGATCCTGCAGCTCCACCAAAGAAACCGCCTCGCCCT
GGAGCTCCCGGTCATCTGGGAAGCCTTGCCAGCCTCAGCAGCCCTGCTGACAGCTACAACGAGGGTGTCAAGCTTCAGCCCCAGGAAATC
AGCCCCCCTCCTACTGCCAACCTGGACCGGTCGAATGATAAGGTGTACGAGAATGTGACGGGCCTGGTGAAAGCTGTCATCGAGATGTCC
AGTAAAATCCAGCCAGCCCCACCAGAGGAGTATGTCCCTATGGTGAAGGAAGTCGGCTTGGCCCTGAGGACATTATTGGCCACTGTGGAT
GAGACCATTCCCCTCCTACCAGCCAGCACCCACCGAGAGATTGAGATGGCACAGAAGCTATTGAACTCTGACCTGGGTGAGCTCATCAAC
AAGATGAAACTGGCCCAGCAGTATGTCATGACCAGCCTCCAGCAAGAGTACAAAAAGCAAATGCTGACTGCTGCTCACGCCCTGGCTGTG
GATGCCAAAAACTTACTCGATGTCATTGACCAAGCAAGACTGAAAATGCTTGGGCAGACGAGACCACACTGAGCCTCCCCTAGGAGCACG
TCTTGCTACCCTCTTTTGAAGATGTTCTCTAGCCTTCCACCAGCAGCGAGGAATTAACCCTGTGTCCTCAGTCGCCAGCACTTACAGCTC
CAACTTTTTTGAATGACCATCTGGTTGAAAAATCTTTCTCATATAAGTTTAACCACACTTTGATTTGGGTTCATTTTTTGTTTTGTTTTT
TTCAATCATGATATTCAGAAAAATCCAGGATCCAAAATGTGGCGTTTTTCTAAGAATGAAAATTATATGTAAGCTTTTAAGCATCATGAA
GAACAATTTATGTTCACATTAAGATACGTTCTAAAGGGGGATGGCCAAGGGGTGACATCTTAATTCCTAAACTACCTTAGCTGCATAGTG
GAAGAGGAGAGCATGAAGCAAAGAATTCCAGGAAACCCAAGAGGCTGAGAATTCTTTTGTCTACCATAGAATTATTATCCAGACTGGAAT
TTTTGTTTGTTAGAACACCCTTCAGTTGCAATATGCTAATCCCACTTTACAAAGAATATAAAAGCTATATTTTGAAGACTTGAGTTATTT
CAGAAAAAACTACAGCCCTTTTTGTCTTACCTGCCTTTTACTTTCGTGTGGATATGTGAAGCATTGGGTCGGGAACTAGCTGTAGAACAC
AACTAAAAACTCATGTCTTTTTTCACAGAATAATGTGCCAGTTTTTTGTAGCAATGTTATTTCTCTTGGAAGCAGAAATGCTTTGTACCA
GAGCACCTCCAAACTGCATTGAGGAGAAGTTCCAGAACCATCCCCTTTTTCCATTTTTATATAATTTATAAAGAAAGATTAAAGCCATGT
TGACTATTTTACAGCCACTGGAGTTAACTAACCCTTCCTTGTATCTGTCTTCCCAGGAGAGAATGAAGCAAAACAGGAATTTGGTTTTCT
TTTGATGTCCAGTTACACCATCCATTCTGTTAATTTTGAAAAAATATACCCTCCCTTTAGTTTGTTGGGGGATATAAATTATTCTCAGGA
AGAATATAATGAACTGTACAGTTACTTTGACCTATTAAAAAGGTGTTACCAGTAAAGTTCTTGTTGTAATATCCTTTCTTTTGGTTCTGT
TTCTTCAGATGGCTTTTCAGGTGACTTGTCAGATAAGATAACATACAAGAGAGTTCCCAATAATTATCAGGAAGCCTCTCACTAATTAGT
TTCTTTTTTTTTATTTAATCTTCTAAACAAGTCAAGGATGTTACCACAGAAGGGTAGCGTGGCGTAAGTTAACCTTTTCATTCCATCGTC
ACCTATTAAATGCAGAGCTCAGGATGGAAGTAGCAATGGTCTTCAATGAAAGAACCTTCCCCTGCGCAGGGTCTCACTATTCCGCTAACT
CGGACTCAAAGCATAATTCACTTGTCAAGGAAATTGTTAGCATTTCCCAGGCCCACCCTAGTCTTGCTAGAATCTCTGTGAGCCACAGAG
CAGGGAGCAAATAGAACTGAGATCTCCAGCACTAGGGACTCAGACTCCAAAGGGAGGGATTTGAGTGAATTTTTTCCAGGTAAATACATG

>2913_2913_7_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000522684_length(amino acids)=604AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLM
EERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSY
NEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQK

--------------------------------------------------------------
>2913_2913_8_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000535192_length(transcript)=2899nt_BP=135nt
GGCCGCGCCGGGGCGGATCGTGCGGCCGGCGGCTCCCTCGCGGCTCGCGGCGTCGGGGCCCGTGGCGCGCGCGCGGCCGCCCCTCGGCCC
CGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTAAAACATGTAAAAACTGT
ACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTGTGAAGCTGATTGGAGTC
ATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAAGGAAATACAGTTTGGAT
CTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTACACAGGGACATTGCTGCT
CGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATAGTACTTACTACAAAGCT
TCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTGACGTATGGATGTTTGGT
GTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTCGAATTGAAAATGGGGAA
AGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCAGCAGGCGGCCCAGGTTT
ACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGGAGTCCAGAAGACAGGCC
ACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGAGGTCCAGCGAAGGATTT
TATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGACTCTACAGTATTGGACCTGCGAGGGATTGGGCAAGTGTTGCCAACC
CATCTGATGGAAGAGCGTCTAATCCGACAGCAACAGGAAATGGAAGAAGATCAGCGCTGGCTGGAAAAAGAGGAAAGATTTCTGAAACCT
GATGTGAGACTCTCTCGAGGCAGTATTGACAGGGAGGATGGAAGTCTTCAGGGTCCGATTGGAAACCAACATATATATCAGCCTGTGGGT
AAACCAGATCCTGCAGCTCCACCAAAGAAACCGCCTCGCCCTGGAGCTCCCGGTCATCTGGGAAGCCTTGCCAGCCTCAGCAGCCCTGCT
GACAGCTACAACGAGGGTGTCAAGCTTCAGCCCCAGGAAATCAGCCCCCCTCCTACTGCCAACCTGGACCGGTCGAATGATAAGGTGTAC
GAGAATGTGACGGGCCTGGTGAAAGCTGTCATCGAGATGTCCAGTAAAATCCAGCCAGCCCCACCAGAGGAGTATGTCCCTATGGTGAAG
GAAGTCGGCTTGGCCCTGAGGACATTATTGGCCACTGTGGATGAGACCATTCCCCTCCTACCAGCCAGCACCCACCGAGAGATTGAGATG
GCACAGAAGCTATTGAACTCTGACCTGGGTGAGCTCATCAACAAGATGAAACTGGCCCAGCAGTATGTCATGACCAGCCTCCAGCAAGAG
TACAAAAAGCAAATGCTGACTGCTGCTCACGCCCTGGCTGTGGATGCCAAAAACTTACTCGATGTCATTGACCAAGCAAGACTGAAAATG
CTTGGGCAGACGAGACCACACTGAGCCTCCCCTAGGAGCACGTCTTGCTACCCTCTTTTGAAGATGTTCTCTAGCCTTCCACCAGCAGCG
AGGAATTAACCCTGTGTCCTCAGTCGCCAGCACTTACAGCTCCAACTTTTTTGAATGACCATCTGGTTGAAAAATCTTTCTCATATAAGT
TTAACCACACTTTGATTTGGGTTCATTTTTTGTTTTGTTTTTTTCAATCATGATATTCAGAAAAATCCAGGATCCAAAATGTGGCGTTTT
TCTAAGAATGAAAATTATATGTAAGCTTTTAAGCATCATGAAGAACAATTTATGTTCACATTAAGATACGTTCTAAAGGGGGATGGCCAA
GGGGTGACATCTTAATTCCTAAACTACCTTAGCTGCATAGTGGAAGAGGAGAGCATGAAGCAAAGAATTCCAGGAAACCCAAGAGGCTGA
GAATTCTTTTGTCTACCATAGAATTATTATCCAGACTGGAATTTTTGTTTGTTAGAACACCCTTCAGTTGCAATATGCTAATCCCACTTT
ACAAAGAATATAAAAGCTATATTTTGAAGACTTGAGTTATTTCAGAAAAAACTACAGCCCTTTTTGTCTTACCTGCCTTTTACTTTCGTG
TGGATATGTGAAGCATTGGGTCGGGAACTAGCTGTAGAACACAACTAAAAACTCATGTCTTTTTTCACAGAATAATGTGCCAGTTTTTTG
TAGCAATGTTATTTCTCTTGGAAGCAGAAATGCTTTGTACCAGAGCACCTCCAAACTGCATTGAGGAGAAGTTCCAGAACCATCCCCTTT
TTCCATTTTTATATAATTTATAAAGAAAGATTAAAGCCATGTTGACTATTTTACAGCCACTGGAGTTAACTAACCCTTCCTTGTATCTGT
CTTCCCAGGAGAGAATGAAGCAAAACAGGAATTTGGTTTTCTTTTGATGTCCAGTTACACCATCCATTCTGTTAATTTTGAAAAAATATA
CCCTCCCTTTAGTTTGTTGGGGGATATAAATTATTCTCAGGAAGAATATAATGAACTGTACAGTTACTTTGACCTATTAAAAAGGTGTTA

>2913_2913_8_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000535192_length(amino acids)=558AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGP
IGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQP
APPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNL

--------------------------------------------------------------
>2913_2913_9_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000538769_length(transcript)=3023nt_BP=135nt
GGCCGCGCCGGGGCGGATCGTGCGGCCGGCGGCTCCCTCGCGGCTCGCGGCGTCGGGGCCCGTGGCGCGCGCGCGGCCGCCCCTCGGCCC
CGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTAAAACATGTAAAAACTGT
ACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTGTGAAGCTGATTGGAGTC
ATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAAGGAAATACAGTTTGGAT
CTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTACACAGGGACATTGCTGCT
CGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATAGTACTTACTACAAAGCT
TCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTGACGTATGGATGTTTGGT
GTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTCGAATTGAAAATGGGGAA
AGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCAGCAGGCGGCCCAGGTTT
ACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGGAGTCCAGAAGACAGGCC
ACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGAGGTCCAGCGAAGGATTT
TATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGTTTCTGGCTACCCTGGTTCACATGGAATCACAGCCATGGCTGGCAGC
ATCTATCCAGGTCAGGCATCTCTTTTGGACCAAACAGATTCATGGAATCATAGACCTCAGGAGATAGCAATGTGGCAGCCCAATGTGGAG
GACTCTACAGTATTGGACCTGCGAGGGATTGGGCAAGTGTTGCCAACCCATCTGATGGAAGAGCGTCTAATCCGACAGCAACAGGAAATG
GAAGAAGATCAGCGCTGGCTGGAAAAAGAGGAAAGATTTCTGAAACCTGATGTGAGACTCTCTCGAGGCAGTATTGACAGGGAGGATGGA
AGTCTTCAGGGTCCGATTGGAAACCAACATATATATCAGCCTGTGGGTAAACCAGATCCTGCAGCTCCACCAAAGAAACCGCCTCGCCCT
GGAGCTCCCGGTCATCTGGGAAGCCTTGCCAGCCTCAGCAGCCCTGCTGACAGCTACAACGAGGGTGTCAAGCTTCAGCCCCAGGAAATC
AGCCCCCCTCCTACTGCCAACCTGGACCGGTCGAATGATAAGGTGTACGAGAATGTGACGGGCCTGGTGAAAGCTGTCATCGAGATGTCC
AGTAAAATCCAGCCAGCCCCACCAGAGGAGTATGTCCCTATGGTGAAGGAAGTCGGCTTGGCCCTGAGGACATTATTGGCCACTGTGGAT
GAGACCATTCCCCTCCTACCAGCCAGCACCCACCGAGAGATTGAGATGGCACAGAAGCTATTGAACTCTGACCTGGGTGAGCTCATCAAC
AAGATGAAACTGGCCCAGCAGTATGTCATGACCAGCCTCCAGCAAGAGTACAAAAAGCAAATGCTGACTGCTGCTCACGCCCTGGCTGTG
GATGCCAAAAACTTACTCGATGTCATTGACCAAGCAAGACTGAAAATGCTTGGGCAGACGAGACCACACTGAGCCTCCCCTAGGAGCACG
TCTTGCTACCCTCTTTTGAAGATGTTCTCTAGCCTTCCACCAGCAGCGAGGAATTAACCCTGTGTCCTCAGTCGCCAGCACTTACAGCTC
CAACTTTTTTGAATGACCATCTGGTTGAAAAATCTTTCTCATATAAGTTTAACCACACTTTGATTTGGGTTCATTTTTTGTTTTGTTTTT
TTCAATCATGATATTCAGAAAAATCCAGGATCCAAAATGTGGCGTTTTTCTAAGAATGAAAATTATATGTAAGCTTTTAAGCATCATGAA
GAACAATTTATGTTCACATTAAGATACGTTCTAAAGGGGGATGGCCAAGGGGTGACATCTTAATTCCTAAACTACCTTAGCTGCATAGTG
GAAGAGGAGAGCATGAAGCAAAGAATTCCAGGAAACCCAAGAGGCTGAGAATTCTTTTGTCTACCATAGAATTATTATCCAGACTGGAAT
TTTTGTTTGTTAGAACACCCTTCAGTTGCAATATGCTAATCCCACTTTACAAAGAATATAAAAGCTATATTTTGAAGACTTGAGTTATTT
CAGAAAAAACTACAGCCCTTTTTGTCTTACCTGCCTTTTACTTTCGTGTGGATATGTGAAGCATTGGGTCGGGAACTAGCTGTAGAACAC
AACTAAAAACTCATGTCTTTTTTCACAGAATAATGTGCCAGTTTTTTGTAGCAATGTTATTTCTCTTGGAAGCAGAAATGCTTTGTACCA
GAGCACCTCCAAACTGCATTGAGGAGAAGTTCCAGAACCATCCCCTTTTTCCATTTTTATATAATTTATAAAGAAAGATTAAAGCCATGT
TGACTATTTTACAGCCACTGGAGTTAACTAACCCTTCCTTGTATCTGTCTTCCCAGGAGAGAATGAAGCAAAACAGGAATTTGGTTTTCT
TTTGATGTCCAGTTACACCATCCATTCTGTTAATTTTGAAAAAATATACCCTCCCTTTAGTTTGTTGGGGGATATAAATTATTCTCAGGA

>2913_2913_9_AGO2-PTK2_AGO2_chr8_141645584_ENST00000220592_PTK2_chr8_141762415_ENST00000538769_length(amino acids)=604AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLM
EERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSY
NEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQK

--------------------------------------------------------------
>2913_2913_10_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000340930_length(transcript)=2989nt_BP=62nt
CGGCCGCCCCTCGGCCCCGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTA
AAACATGTAAAAACTGTACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTG
TGAAGCTGATTGGAGTCATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAA
GGAAATACAGTTTGGATCTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTAC
ACAGGGACATTGCTGCTCGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATA
GTACTTACTACAAAGCTTCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTG
ACGTATGGATGTTTGGTGTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTC
GAATTGAAAATGGGGAAAGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCA
GCAGGCGGCCCAGGTTTACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGG
AGTCCAGAAGACAGGCCACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGA
GGTCCAGCGAAGGATTTTATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGTTTCTGGCTACCCTGGTTCACATGGAATCA
CAGCCATGGCTGGCAGCATCTATCCAGGTCAGGCATCTCTTTTGGACCAAACAGATTCATGGAATCATAGACCTCAGGAGATAGCAATGT
GGCAGCCCAATGTGGAGGACTCTACAGTATTGGACCTGCGAGGGATTGGGCAAGTGTTGCCAACCCATCTGATGGAAGAGCGTCTAATCC
GACAGCAACAGGAAATGGAAGAAGATCAGCGCTGGCTGGAAAAAGAGGAAAGATTTCTGAAACCTGATGTGAGACTCTCTCGAGGCAGTA
TTGACAGGGAGGATGGAAGTCTTCAGGGTCCGATTGGAAACCAACATATATATCAGCCTGTGGGTAAACCAGGTAAAGAAGAAAAGAATT
GGGCGGAAAGAAATCCTGCAGCTCCACCAAAGAAACCGCCTCGCCCTGGAGCTCCCGGTCATCTGGGAAGCCTTGCCAGCCTCAGCAGCC
CTGCTGACAGCTACAACGAGGGTGTCAAGCCATGGAGGCTTCAGCCCCAGGAAATCAGCCCCCCTCCTACTGCCAACCTGGACCGGTCGA
ATGATAAGGTGTACGAGAATGTGACGGGCCTGGTGAAAGCTGTCATCGAGATGTCCAGTAAAATCCAGCCAGCCCCACCAGAGGAGTATG
TCCCTATGGTGAAGGAAGTCGGCTTGGCCCTGAGGACATTATTGGCCACTGTGGATGAGACCATTCCCCTCCTACCAGCCAGCACCCACC
GAGAGATTGAGATGGCACAGAAGCTATTGAACTCTGACCTGGGTGAGCTCATCAACAAGATGAAACTGGCCCAGCAGTATGTCATGACCA
GCCTCCAGCAAGAGTACAAAAAGCAAATGCTGACTGCTGCTCACGCCCTGGCTGTGGATGCCAAAAACTTACTCGATGTCATTGACCAAG
CAAGACTGAAAATGCTTGGGCAGACGAGACCACACTGAGCCTCCCCTAGGAGCACGTCTTGCTACCCTCTTTTGAAGATGTTCTCTAGCC
TTCCACCAGCAGCGAGGAATTAACCCTGTGTCCTCAGTCGCCAGCACTTACAGCTCCAACTTTTTTGAATGACCATCTGGTTGAAAAATC
TTTCTCATATAAGTTTAACCACACTTTGATTTGGGTTCATTTTTTGTTTTGTTTTTTTCAATCATGATATTCAGAAAAATCCAGGATCCA
AAATGTGGCGTTTTTCTAAGAATGAAAATTATATGTAAGCTTTTAAGCATCATGAAGAACAATTTATGTTCACATTAAGATACGTTCTAA
AGGGGGATGGCCAAGGGGTGACATCTTAATTCCTAAACTACCTTAGCTGCATAGTGGAAGAGGAGAGCATGAAGCAAAGAATTCCAGGAA
ACCCAAGAGGCTGAGAATTCTTTTGTCTACCATAGAATTATTATCCAGACTGGAATTTTTGTTTGTTAGAACACCCTTCAGTTGCAATAT
GCTAATCCCACTTTACAAAGAATATAAAAGCTATATTTTGAAGACTTGAGTTATTTCAGAAAAAACTACAGCCCTTTTTGTCTTACCTGC
CTTTTACTTTCGTGTGGATATGTGAAGCATTGGGTCGGGAACTAGCTGTAGAACACAACTAAAAACTCATGTCTTTTTTCACAGAATAAT
GTGCCAGTTTTTTGTAGCAATGTTATTTCTCTTGGAAGCAGAAATGCTTTGTACCAGAGCACCTCCAAACTGCATTGAGGAGAAGTTCCA
GAACCATCCCCTTTTTCCATTTTTATATAATTTATAAAGAAAGATTAAAGCCATGTTGACTATTTTACAGCCACTGGAGTTAACTAACCC
TTCCTTGTATCTGTCTTCCCAGGAGAGAATGAAGCAAAACAGGAATTTGGTTTTCTTTTGATGTCCAGTTACACCATCCATTCTGTTAAT
TTTGAAAAAATATACCCTCCCTTTAGTTTGTTGGGGGATATAAATTATTCTCAGGAAGAATATAATGAACTGTACAGTTACTTTGACCTA

>2913_2913_10_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000340930_length(amino acids)=617AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLM
EERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPGKEEKNWAERNPAAPPKKPPRPGAPGHLGSL
ASLSSPADSYNEGVKPWRLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLL

--------------------------------------------------------------
>2913_2913_11_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000395218_length(transcript)=2992nt_BP=62nt
CGGCCGCCCCTCGGCCCCGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTA
AAACATGTAAAAACTGTACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTG
TGAAGCTGATTGGAGTCATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAA
GGAAATACAGTTTGGATCTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTAC
ACAGGGACATTGCTGCTCGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATA
GTACTTACTACAAAGCTTCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTG
ACGTATGGATGTTTGGTGTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTC
GAATTGAAAATGGGGAAAGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCA
GCAGGCGGCCCAGGTTTACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGG
AGTCCAGAAGACAGGCCACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGA
GGTCCAGCGAAGGATTTTATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGTTTCTGGCTACCCTGGTTCACATGGAATCA
CAGCCATGGCTGGCAGCATCTATCCAGGTCAGGCATCTCTTTTGGACCAAACAGATTCATGGAATCATAGACCTCAGGAGATAGCAATGT
GGCAGCCCAATGTGGAGGACTCTACAGTATTGGACCTGCGAGGGATTGGGCAAGTGTTGCCAACCCATCTGATGGAAGAGCGTCTAATCC
GACAGCAACAGGAAATGGAAGAAGATCAGCGCTGGCTGGAAAAAGAGGAAAGATTTCTGAAACCTGATGTGAGACTCTCTCGAGGCAGTA
TTGACAGGGAGGATGGAAGTCTTCAGGGTCCGATTGGAAACCAACATATATATCAGCCTGTGGGTAAACCAGGTAAAGAAGAAAAGAATT
GGGCGGAAAGAAATCCTGCAGCTCCACCAAAGAAACCGCCTCGCCCTGGAGCTCCCGGTCATCTGGGAAGCCTTGCCAGCCTCAGCAGCC
CTGCTGACAGCTACAACGAGGGTGTCAAGCCAAATCAGCTTCAGCCCCAGGAAATCAGCCCCCCTCCTACTGCCAACCTGGACCGGTCGA
ATGATAAGGTGTACGAGAATGTGACGGGCCTGGTGAAAGCTGTCATCGAGATGTCCAGTAAAATCCAGCCAGCCCCACCAGAGGAGTATG
TCCCTATGGTGAAGGAAGTCGGCTTGGCCCTGAGGACATTATTGGCCACTGTGGATGAGACCATTCCCCTCCTACCAGCCAGCACCCACC
GAGAGATTGAGATGGCACAGAAGCTATTGAACTCTGACCTGGGTGAGCTCATCAACAAGATGAAACTGGCCCAGCAGTATGTCATGACCA
GCCTCCAGCAAGAGTACAAAAAGCAAATGCTGACTGCTGCTCACGCCCTGGCTGTGGATGCCAAAAACTTACTCGATGTCATTGACCAAG
CAAGACTGAAAATGCTTGGGCAGACGAGACCACACTGAGCCTCCCCTAGGAGCACGTCTTGCTACCCTCTTTTGAAGATGTTCTCTAGCC
TTCCACCAGCAGCGAGGAATTAACCCTGTGTCCTCAGTCGCCAGCACTTACAGCTCCAACTTTTTTGAATGACCATCTGGTTGAAAAATC
TTTCTCATATAAGTTTAACCACACTTTGATTTGGGTTCATTTTTTGTTTTGTTTTTTTCAATCATGATATTCAGAAAAATCCAGGATCCA
AAATGTGGCGTTTTTCTAAGAATGAAAATTATATGTAAGCTTTTAAGCATCATGAAGAACAATTTATGTTCACATTAAGATACGTTCTAA
AGGGGGATGGCCAAGGGGTGACATCTTAATTCCTAAACTACCTTAGCTGCATAGTGGAAGAGGAGAGCATGAAGCAAAGAATTCCAGGAA
ACCCAAGAGGCTGAGAATTCTTTTGTCTACCATAGAATTATTATCCAGACTGGAATTTTTGTTTGTTAGAACACCCTTCAGTTGCAATAT
GCTAATCCCACTTTACAAAGAATATAAAAGCTATATTTTGAAGACTTGAGTTATTTCAGAAAAAACTACAGCCCTTTTTGTCTTACCTGC
CTTTTACTTTCGTGTGGATATGTGAAGCATTGGGTCGGGAACTAGCTGTAGAACACAACTAAAAACTCATGTCTTTTTTCACAGAATAAT
GTGCCAGTTTTTTGTAGCAATGTTATTTCTCTTGGAAGCAGAAATGCTTTGTACCAGAGCACCTCCAAACTGCATTGAGGAGAAGTTCCA
GAACCATCCCCTTTTTCCATTTTTATATAATTTATAAAGAAAGATTAAAGCCATGTTGACTATTTTACAGCCACTGGAGTTAACTAACCC
TTCCTTGTATCTGTCTTCCCAGGAGAGAATGAAGCAAAACAGGAATTTGGTTTTCTTTTGATGTCCAGTTACACCATCCATTCTGTTAAT
TTTGAAAAAATATACCCTCCCTTTAGTTTGTTGGGGGATATAAATTATTCTCAGGAAGAATATAATGAACTGTACAGTTACTTTGACCTA

>2913_2913_11_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000395218_length(amino acids)=617AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLM
EERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPGKEEKNWAERNPAAPPKKPPRPGAPGHLGSL
ASLSSPADSYNEGVKPNQLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLL

--------------------------------------------------------------
>2913_2913_12_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000517887_length(transcript)=2953nt_BP=62nt
CGGCCGCCCCTCGGCCCCGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTA
AAACATGTAAAAACTGTACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTG
TGAAGCTGATTGGAGTCATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAA
GGAAATACAGTTTGGATCTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTAC
ACAGGGACATTGCTGCTCGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATA
GTACTTACTACAAAGCTTCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTG
ACGTATGGATGTTTGGTGTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTC
GAATTGAAAATGGGGAAAGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCA
GCAGGCGGCCCAGGTTTACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGG
AGTCCAGAAGACAGGCCACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGA
GGTCCAGCGAAGGATTTTATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGTTTCTGGCTACCCTGGTTCACATGGAATCA
CAGCCATGGCTGGCAGCATCTATCCAGGTCAGGCATCTCTTTTGGACCAAACAGATTCATGGAATCATAGACCTCAGGAGATAGCAATGT
GGCAGCCCAATGTGGAGGACTCTACAGTATTGGACCTGCGAGGGATTGGGCAAGTGTTGCCAACCCATCTGATGGAAGAGCGTCTAATCC
GACAGCAACAGGAAATGGAAGAAGATCAGCGCTGGCTGGAAAAAGAGGAAAGATTTCTGAAACCTGATGTGAGACTCTCTCGAGGCAGTA
TTGACAGGGAGGATGGAAGTCTTCAGGGTCCGATTGGAAACCAACATATATATCAGCCTGTGGGTAAACCAGATCCTGCAGCTCCACCAA
AGAAACCGCCTCGCCCTGGAGCTCCCGGTCATCTGGGAAGCCTTGCCAGCCTCAGCAGCCCTGCTGACAGCTACAACGAGGGTGTCAAGC
TTCAGCCCCAGGAAATCAGCCCCCCTCCTACTGCCAACCTGGACCGGTCGAATGATAAGGTGTACGAGAATGTGACGGGCCTGGTGAAAG
CTGTCATCGAGATGTCCAGTAAAATCCAGCCAGCCCCACCAGAGGAGTATGTCCCTATGGTGAAGGAAGTCGGCTTGGCCCTGAGGACAT
TATTGGCCACTGTGGATGAGACCATTCCCCTCCTACCAGCCAGCACCCACCGAGAGATTGAGATGGCACAGAAGCTATTGAACTCTGACC
TGGGTGAGCTCATCAACAAGATGAAACTGGCCCAGCAGTATGTCATGACCAGCCTCCAGCAAGAGTACAAAAAGCAAATGCTGACTGCTG
CTCACGCCCTGGCTGTGGATGCCAAAAACTTACTCGATGTCATTGACCAAGCAAGACTGAAAATGCTTGGGCAGACGAGACCACACTGAG
CCTCCCCTAGGAGCACGTCTTGCTACCCTCTTTTGAAGATGTTCTCTAGCCTTCCACCAGCAGCGAGGAATTAACCCTGTGTCCTCAGTC
GCCAGCACTTACAGCTCCAACTTTTTTGAATGACCATCTGGTTGAAAAATCTTTCTCATATAAGTTTAACCACACTTTGATTTGGGTTCA
TTTTTTGTTTTGTTTTTTTCAATCATGATATTCAGAAAAATCCAGGATCCAAAATGTGGCGTTTTTCTAAGAATGAAAATTATATGTAAG
CTTTTAAGCATCATGAAGAACAATTTATGTTCACATTAAGATACGTTCTAAAGGGGGATGGCCAAGGGGTGACATCTTAATTCCTAAACT
ACCTTAGCTGCATAGTGGAAGAGGAGAGCATGAAGCAAAGAATTCCAGGAAACCCAAGAGGCTGAGAATTCTTTTGTCTACCATAGAATT
ATTATCCAGACTGGAATTTTTGTTTGTTAGAACACCCTTCAGTTGCAATATGCTAATCCCACTTTACAAAGAATATAAAAGCTATATTTT
GAAGACTTGAGTTATTTCAGAAAAAACTACAGCCCTTTTTGTCTTACCTGCCTTTTACTTTCGTGTGGATATGTGAAGCATTGGGTCGGG
AACTAGCTGTAGAACACAACTAAAAACTCATGTCTTTTTTCACAGAATAATGTGCCAGTTTTTTGTAGCAATGTTATTTCTCTTGGAAGC
AGAAATGCTTTGTACCAGAGCACCTCCAAACTGCATTGAGGAGAAGTTCCAGAACCATCCCCTTTTTCCATTTTTATATAATTTATAAAG
AAAGATTAAAGCCATGTTGACTATTTTACAGCCACTGGAGTTAACTAACCCTTCCTTGTATCTGTCTTCCCAGGAGAGAATGAAGCAAAA
CAGGAATTTGGTTTTCTTTTGATGTCCAGTTACACCATCCATTCTGTTAATTTTGAAAAAATATACCCTCCCTTTAGTTTGTTGGGGGAT

>2913_2913_12_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000517887_length(amino acids)=604AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLM
EERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSY
NEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQK

--------------------------------------------------------------
>2913_2913_13_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000519419_length(transcript)=2725nt_BP=62nt
CGGCCGCCCCTCGGCCCCGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTA
AAACATGTAAAAACTGTACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTG
TGAAGCTGATTGGAGTCATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAA
GGAAATACAGTTTGGATCTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTAC
ACAGGGACATTGCTGCTCGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATA
GTACTTACTACAAAGCTTCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTG
ACGTATGGATGTTTGGTGTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTC
GAATTGAAAATGGGGAAAGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCA
GCAGGCGGCCCAGGTTTACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGG
AGTCCAGAAGACAGGCCACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGA
GGTCCAGCGAAGGATTTTATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGTTTCTGGCTACCCTGGTTCACATGGAATCA
CAGCCATGGCTGGCAGCATCTATCCAGGTCAGGCATCTCTTTTGGACCAAACAGATTCATGGAATCATAGACCTCAGGAGATAGCAATGT
GGCAGCCCAATGTGGAGGACTCTACAGTATTGGACCTGCGAGGGATTGGGCAAGTGTTGCCAACCCATCTGATGGAAGAGCGTCTAATCC
GACAGCAACAGGAAATGGAAGAAGATCAGCGCTGGCTGGAAAAAGAGGAAAGATTTCTGAAACCTGATGTGAGACTCTCTCGAGGCAGTA
TTGACAGGGAGGATGGAAGTCTTCAGGGTCCGATTGGAAACCAACATATATATCAGCCTGTGGGTAAACCAGATCCTGCAGCTCCACCAA
AGAAACCGCCTCGCCCTGGAGCTCCCGGTCATCTGGGAAGCCTTGCCAGCCTCAGCAGCCCTGCTGACAGCTACAACGAGGGTGTCAAGC
TTCAGCCCCAGGAAATCAGCCCCCCTCCTACTGCCAACCTGGACCGGTCGAATGATAAGGTGTACGAGAATGTGACGGGCCTGGTGAAAG
CTGTCATCGAGATGTCCAGTAAAATCCAGCCAGCCCCACCAGAGGAGTATGTCCCTATGGTGAAGGAAGTCGGCTTGGCCCTGAGGACAT
TATTGGCCACTGTGGATGAGACCATTCCCCTCCTACCAGCCAGCACCCACCGAGAGATTGAGATGGCACAGAAGCTATTGAACTCTGACC
TGGGTGAGCTCATCAACAAGATGAAACTGGCCCAGCAGTATGTCATGACCAGCCTCCAGCAAGAGTACAAAAAGCAAATGCTGACTGCTG
CTCACGCCCTGGCTGTGGATGCCAAAAACTTACTCGATGTCATTGACCAAGCAAGACTGAAAATGCTTGGGCAGACGAGACCACACTGAG
CCTCCCCTAGGAGCACGTCTTGCTACCCTCTTTTGAAGATGTTCTCTAGCCTTCCACCAGCAGCGAGGAATTAACCCTGTGTCCTCAGTC
GCCAGCACTTACAGCTCCAACTTTTTTGAATGACCATCTGGTTGAAAAATCTTTCTCATATAAGTTTAACCACACTTTGATTTGGGTTCA
TTTTTTGTTTTGTTTTTTTCAATCATGATATTCAGAAAAATCCAGGATCCAAAATGTGGCGTTTTTCTAAGAATGAAAATTATATGTAAG
CTTTTAAGCATCATGAAGAACAATTTATGTTCACATTAAGATACGTTCTAAAGGGGGATGGCCAAGGGGTGACATCTTAATTCCTAAACT
ACCTTAGCTGCATAGTGGAAGAGGAGAGCATGAAGCAAAGAATTCCAGGAAACCCAAGAGGCTGAGAATTCTTTTGTCTACCATAGAATT
ATTATCCAGACTGGAATTTTTGTTTGTTAGAACACCCTTCAGTTGCAATATGCTAATCCCACTTTACAAAGAATATAAAAGCTATATTTT
GAAGACTTGAGTTATTTCAGAAAAAACTACAGCCCTTTTTGTCTTACCTGCCTTTTACTTTCGTGTGGATATGTGAAGCATTGGGTCGGG
AACTAGCTGTAGAACACAACTAAAAACTCATGTCTTTTTTCACAGAATAATGTGCCAGTTTTTTGTAGCAATGTTATTTCTCTTGGAAGC
AGAAATGCTTTGTACCAGAGCACCTCCAAACTGCATTGAGGAGAAGTTCCAGAACCATCCCCTTTTTCCATTTTTATATAATTTATAAAG

>2913_2913_13_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000519419_length(amino acids)=604AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLM
EERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSY
NEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQK

--------------------------------------------------------------
>2913_2913_14_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000519465_length(transcript)=2953nt_BP=62nt
CGGCCGCCCCTCGGCCCCGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTA
AAACATGTAAAAACTGTACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTG
TGAAGCTGATTGGAGTCATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAA
GGAAATACAGTTTGGATCTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTAC
ACAGGGACATTGCTGCTCGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATA
GTACTTACTACAAAGCTTCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTG
ACGTATGGATGTTTGGTGTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTC
GAATTGAAAATGGGGAAAGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCA
GCAGGCGGCCCAGGTTTACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGG
AGTCCAGAAGACAGGCCACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGA
GGTCCAGCGAAGGATTTTATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGTTTCTGGCTACCCTGGTTCACATGGAATCA
CAGCCATGGCTGGCAGCATCTATCCAGGTCAGGCATCTCTTTTGGACCAAACAGATTCATGGAATCATAGACCTCAGGAGATAGCAATGT
GGCAGCCCAATGTGGAGGACTCTACAGTATTGGACCTGCGAGGGATTGGGCAAGTGTTGCCAACCCATCTGATGGAAGAGCGTCTAATCC
GACAGCAACAGGAAATGGAAGAAGATCAGCGCTGGCTGGAAAAAGAGGAAAGATTTCTGAAACCTGATGTGAGACTCTCTCGAGGCAGTA
TTGACAGGGAGGATGGAAGTCTTCAGGGTCCGATTGGAAACCAACATATATATCAGCCTGTGGGTAAACCAGATCCTGCAGCTCCACCAA
AGAAACCGCCTCGCCCTGGAGCTCCCGGTCATCTGGGAAGCCTTGCCAGCCTCAGCAGCCCTGCTGACAGCTACAACGAGGGTGTCAAGC
TTCAGCCCCAGGAAATCAGCCCCCCTCCTACTGCCAACCTGGACCGGTCGAATGATAAGGTGTACGAGAATGTGACGGGCCTGGTGAAAG
CTGTCATCGAGATGTCCAGTAAAATCCAGCCAGCCCCACCAGAGGAGTATGTCCCTATGGTGAAGGAAGTCGGCTTGGCCCTGAGGACAT
TATTGGCCACTGTGGATGAGACCATTCCCCTCCTACCAGCCAGCACCCACCGAGAGATTGAGATGGCACAGAAGCTATTGAACTCTGACC
TGGGTGAGCTCATCAACAAGATGAAACTGGCCCAGCAGTATGTCATGACCAGCCTCCAGCAAGAGTACAAAAAGCAAATGCTGACTGCTG
CTCACGCCCTGGCTGTGGATGCCAAAAACTTACTCGATGTCATTGACCAAGCAAGACTGAAAATGCTTGGGCAGACGAGACCACACTGAG
CCTCCCCTAGGAGCACGTCTTGCTACCCTCTTTTGAAGATGTTCTCTAGCCTTCCACCAGCAGCGAGGAATTAACCCTGTGTCCTCAGTC
GCCAGCACTTACAGCTCCAACTTTTTTGAATGACCATCTGGTTGAAAAATCTTTCTCATATAAGTTTAACCACACTTTGATTTGGGTTCA
TTTTTTGTTTTGTTTTTTTCAATCATGATATTCAGAAAAATCCAGGATCCAAAATGTGGCGTTTTTCTAAGAATGAAAATTATATGTAAG
CTTTTAAGCATCATGAAGAACAATTTATGTTCACATTAAGATACGTTCTAAAGGGGGATGGCCAAGGGGTGACATCTTAATTCCTAAACT
ACCTTAGCTGCATAGTGGAAGAGGAGAGCATGAAGCAAAGAATTCCAGGAAACCCAAGAGGCTGAGAATTCTTTTGTCTACCATAGAATT
ATTATCCAGACTGGAATTTTTGTTTGTTAGAACACCCTTCAGTTGCAATATGCTAATCCCACTTTACAAAGAATATAAAAGCTATATTTT
GAAGACTTGAGTTATTTCAGAAAAAACTACAGCCCTTTTTGTCTTACCTGCCTTTTACTTTCGTGTGGATATGTGAAGCATTGGGTCGGG
AACTAGCTGTAGAACACAACTAAAAACTCATGTCTTTTTTCACAGAATAATGTGCCAGTTTTTTGTAGCAATGTTATTTCTCTTGGAAGC
AGAAATGCTTTGTACCAGAGCACCTCCAAACTGCATTGAGGAGAAGTTCCAGAACCATCCCCTTTTTCCATTTTTATATAATTTATAAAG
AAAGATTAAAGCCATGTTGACTATTTTACAGCCACTGGAGTTAACTAACCCTTCCTTGTATCTGTCTTCCCAGGAGAGAATGAAGCAAAA
CAGGAATTTGGTTTTCTTTTGATGTCCAGTTACACCATCCATTCTGTTAATTTTGAAAAAATATACCCTCCCTTTAGTTTGTTGGGGGAT

>2913_2913_14_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000519465_length(amino acids)=604AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLM
EERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSY
NEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQK

--------------------------------------------------------------
>2913_2913_15_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000521059_length(transcript)=2953nt_BP=62nt
CGGCCGCCCCTCGGCCCCGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTA
AAACATGTAAAAACTGTACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTG
TGAAGCTGATTGGAGTCATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAA
GGAAATACAGTTTGGATCTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTAC
ACAGGGACATTGCTGCTCGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATA
GTACTTACTACAAAGCTTCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTG
ACGTATGGATGTTTGGTGTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTC
GAATTGAAAATGGGGAAAGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCA
GCAGGCGGCCCAGGTTTACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGG
AGTCCAGAAGACAGGCCACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGA
GGTCCAGCGAAGGATTTTATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGTTTCTGGCTACCCTGGTTCACATGGAATCA
CAGCCATGGCTGGCAGCATCTATCCAGGTCAGGCATCTCTTTTGGACCAAACAGATTCATGGAATCATAGACCTCAGGAGATAGCAATGT
GGCAGCCCAATGTGGAGGACTCTACAGTATTGGACCTGCGAGGGATTGGGCAAGTGTTGCCAACCCATCTGATGGAAGAGCGTCTAATCC
GACAGCAACAGGAAATGGAAGAAGATCAGCGCTGGCTGGAAAAAGAGGAAAGATTTCTGAAACCTGATGTGAGACTCTCTCGAGGCAGTA
TTGACAGGGAGGATGGAAGTCTTCAGGGTCCGATTGGAAACCAACATATATATCAGCCTGTGGGTAAACCAGATCCTGCAGCTCCACCAA
AGAAACCGCCTCGCCCTGGAGCTCCCGGTCATCTGGGAAGCCTTGCCAGCCTCAGCAGCCCTGCTGACAGCTACAACGAGGGTGTCAAGC
TTCAGCCCCAGGAAATCAGCCCCCCTCCTACTGCCAACCTGGACCGGTCGAATGATAAGGTGTACGAGAATGTGACGGGCCTGGTGAAAG
CTGTCATCGAGATGTCCAGTAAAATCCAGCCAGCCCCACCAGAGGAGTATGTCCCTATGGTGAAGGAAGTCGGCTTGGCCCTGAGGACAT
TATTGGCCACTGTGGATGAGACCATTCCCCTCCTACCAGCCAGCACCCACCGAGAGATTGAGATGGCACAGAAGCTATTGAACTCTGACC
TGGGTGAGCTCATCAACAAGATGAAACTGGCCCAGCAGTATGTCATGACCAGCCTCCAGCAAGAGTACAAAAAGCAAATGCTGACTGCTG
CTCACGCCCTGGCTGTGGATGCCAAAAACTTACTCGATGTCATTGACCAAGCAAGACTGAAAATGCTTGGGCAGACGAGACCACACTGAG
CCTCCCCTAGGAGCACGTCTTGCTACCCTCTTTTGAAGATGTTCTCTAGCCTTCCACCAGCAGCGAGGAATTAACCCTGTGTCCTCAGTC
GCCAGCACTTACAGCTCCAACTTTTTTGAATGACCATCTGGTTGAAAAATCTTTCTCATATAAGTTTAACCACACTTTGATTTGGGTTCA
TTTTTTGTTTTGTTTTTTTCAATCATGATATTCAGAAAAATCCAGGATCCAAAATGTGGCGTTTTTCTAAGAATGAAAATTATATGTAAG
CTTTTAAGCATCATGAAGAACAATTTATGTTCACATTAAGATACGTTCTAAAGGGGGATGGCCAAGGGGTGACATCTTAATTCCTAAACT
ACCTTAGCTGCATAGTGGAAGAGGAGAGCATGAAGCAAAGAATTCCAGGAAACCCAAGAGGCTGAGAATTCTTTTGTCTACCATAGAATT
ATTATCCAGACTGGAATTTTTGTTTGTTAGAACACCCTTCAGTTGCAATATGCTAATCCCACTTTACAAAGAATATAAAAGCTATATTTT
GAAGACTTGAGTTATTTCAGAAAAAACTACAGCCCTTTTTGTCTTACCTGCCTTTTACTTTCGTGTGGATATGTGAAGCATTGGGTCGGG
AACTAGCTGTAGAACACAACTAAAAACTCATGTCTTTTTTCACAGAATAATGTGCCAGTTTTTTGTAGCAATGTTATTTCTCTTGGAAGC
AGAAATGCTTTGTACCAGAGCACCTCCAAACTGCATTGAGGAGAAGTTCCAGAACCATCCCCTTTTTCCATTTTTATATAATTTATAAAG
AAAGATTAAAGCCATGTTGACTATTTTACAGCCACTGGAGTTAACTAACCCTTCCTTGTATCTGTCTTCCCAGGAGAGAATGAAGCAAAA
CAGGAATTTGGTTTTCTTTTGATGTCCAGTTACACCATCCATTCTGTTAATTTTGAAAAAATATACCCTCCCTTTAGTTTGTTGGGGGAT

>2913_2913_15_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000521059_length(amino acids)=604AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLM
EERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSY
NEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQK

--------------------------------------------------------------
>2913_2913_16_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000522684_length(transcript)=3455nt_BP=62nt
CGGCCGCCCCTCGGCCCCGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTA
AAACATGTAAAAACTGTACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTG
TGAAGCTGATTGGAGTCATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAA
GGAAATACAGTTTGGATCTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTAC
ACAGGGACATTGCTGCTCGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATA
GTACTTACTACAAAGCTTCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTG
ACGTATGGATGTTTGGTGTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTC
GAATTGAAAATGGGGAAAGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCA
GCAGGCGGCCCAGGTTTACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGG
AGTCCAGAAGACAGGCCACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGA
GGTCCAGCGAAGGATTTTATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGTTTCTGGCTACCCTGGTTCACATGGAATCA
CAGCCATGGCTGGCAGCATCTATCCAGGTCAGGCATCTCTTTTGGACCAAACAGATTCATGGAATCATAGACCTCAGGAGATAGCAATGT
GGCAGCCCAATGTGGAGGACTCTACAGTATTGGACCTGCGAGGGATTGGGCAAGTGTTGCCAACCCATCTGATGGAAGAGCGTCTAATCC
GACAGCAACAGGAAATGGAAGAAGATCAGCGCTGGCTGGAAAAAGAGGAAAGATTTCTGAAACCTGATGTGAGACTCTCTCGAGGCAGTA
TTGACAGGGAGGATGGAAGTCTTCAGGGTCCGATTGGAAACCAACATATATATCAGCCTGTGGGTAAACCAGATCCTGCAGCTCCACCAA
AGAAACCGCCTCGCCCTGGAGCTCCCGGTCATCTGGGAAGCCTTGCCAGCCTCAGCAGCCCTGCTGACAGCTACAACGAGGGTGTCAAGC
TTCAGCCCCAGGAAATCAGCCCCCCTCCTACTGCCAACCTGGACCGGTCGAATGATAAGGTGTACGAGAATGTGACGGGCCTGGTGAAAG
CTGTCATCGAGATGTCCAGTAAAATCCAGCCAGCCCCACCAGAGGAGTATGTCCCTATGGTGAAGGAAGTCGGCTTGGCCCTGAGGACAT
TATTGGCCACTGTGGATGAGACCATTCCCCTCCTACCAGCCAGCACCCACCGAGAGATTGAGATGGCACAGAAGCTATTGAACTCTGACC
TGGGTGAGCTCATCAACAAGATGAAACTGGCCCAGCAGTATGTCATGACCAGCCTCCAGCAAGAGTACAAAAAGCAAATGCTGACTGCTG
CTCACGCCCTGGCTGTGGATGCCAAAAACTTACTCGATGTCATTGACCAAGCAAGACTGAAAATGCTTGGGCAGACGAGACCACACTGAG
CCTCCCCTAGGAGCACGTCTTGCTACCCTCTTTTGAAGATGTTCTCTAGCCTTCCACCAGCAGCGAGGAATTAACCCTGTGTCCTCAGTC
GCCAGCACTTACAGCTCCAACTTTTTTGAATGACCATCTGGTTGAAAAATCTTTCTCATATAAGTTTAACCACACTTTGATTTGGGTTCA
TTTTTTGTTTTGTTTTTTTCAATCATGATATTCAGAAAAATCCAGGATCCAAAATGTGGCGTTTTTCTAAGAATGAAAATTATATGTAAG
CTTTTAAGCATCATGAAGAACAATTTATGTTCACATTAAGATACGTTCTAAAGGGGGATGGCCAAGGGGTGACATCTTAATTCCTAAACT
ACCTTAGCTGCATAGTGGAAGAGGAGAGCATGAAGCAAAGAATTCCAGGAAACCCAAGAGGCTGAGAATTCTTTTGTCTACCATAGAATT
ATTATCCAGACTGGAATTTTTGTTTGTTAGAACACCCTTCAGTTGCAATATGCTAATCCCACTTTACAAAGAATATAAAAGCTATATTTT
GAAGACTTGAGTTATTTCAGAAAAAACTACAGCCCTTTTTGTCTTACCTGCCTTTTACTTTCGTGTGGATATGTGAAGCATTGGGTCGGG
AACTAGCTGTAGAACACAACTAAAAACTCATGTCTTTTTTCACAGAATAATGTGCCAGTTTTTTGTAGCAATGTTATTTCTCTTGGAAGC
AGAAATGCTTTGTACCAGAGCACCTCCAAACTGCATTGAGGAGAAGTTCCAGAACCATCCCCTTTTTCCATTTTTATATAATTTATAAAG
AAAGATTAAAGCCATGTTGACTATTTTACAGCCACTGGAGTTAACTAACCCTTCCTTGTATCTGTCTTCCCAGGAGAGAATGAAGCAAAA
CAGGAATTTGGTTTTCTTTTGATGTCCAGTTACACCATCCATTCTGTTAATTTTGAAAAAATATACCCTCCCTTTAGTTTGTTGGGGGAT
ATAAATTATTCTCAGGAAGAATATAATGAACTGTACAGTTACTTTGACCTATTAAAAAGGTGTTACCAGTAAAGTTCTTGTTGTAATATC
CTTTCTTTTGGTTCTGTTTCTTCAGATGGCTTTTCAGGTGACTTGTCAGATAAGATAACATACAAGAGAGTTCCCAATAATTATCAGGAA
GCCTCTCACTAATTAGTTTCTTTTTTTTTATTTAATCTTCTAAACAAGTCAAGGATGTTACCACAGAAGGGTAGCGTGGCGTAAGTTAAC
CTTTTCATTCCATCGTCACCTATTAAATGCAGAGCTCAGGATGGAAGTAGCAATGGTCTTCAATGAAAGAACCTTCCCCTGCGCAGGGTC
TCACTATTCCGCTAACTCGGACTCAAAGCATAATTCACTTGTCAAGGAAATTGTTAGCATTTCCCAGGCCCACCCTAGTCTTGCTAGAAT
CTCTGTGAGCCACAGAGCAGGGAGCAAATAGAACTGAGATCTCCAGCACTAGGGACTCAGACTCCAAAGGGAGGGATTTGAGTGAATTTT

>2913_2913_16_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000522684_length(amino acids)=604AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLM
EERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSY
NEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQK

--------------------------------------------------------------
>2913_2913_17_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000535192_length(transcript)=2826nt_BP=62nt
CGGCCGCCCCTCGGCCCCGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTA
AAACATGTAAAAACTGTACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTG
TGAAGCTGATTGGAGTCATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAA
GGAAATACAGTTTGGATCTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTAC
ACAGGGACATTGCTGCTCGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATA
GTACTTACTACAAAGCTTCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTG
ACGTATGGATGTTTGGTGTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTC
GAATTGAAAATGGGGAAAGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCA
GCAGGCGGCCCAGGTTTACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGG
AGTCCAGAAGACAGGCCACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGA
GGTCCAGCGAAGGATTTTATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGACTCTACAGTATTGGACCTGCGAGGGATTG
GGCAAGTGTTGCCAACCCATCTGATGGAAGAGCGTCTAATCCGACAGCAACAGGAAATGGAAGAAGATCAGCGCTGGCTGGAAAAAGAGG
AAAGATTTCTGAAACCTGATGTGAGACTCTCTCGAGGCAGTATTGACAGGGAGGATGGAAGTCTTCAGGGTCCGATTGGAAACCAACATA
TATATCAGCCTGTGGGTAAACCAGATCCTGCAGCTCCACCAAAGAAACCGCCTCGCCCTGGAGCTCCCGGTCATCTGGGAAGCCTTGCCA
GCCTCAGCAGCCCTGCTGACAGCTACAACGAGGGTGTCAAGCTTCAGCCCCAGGAAATCAGCCCCCCTCCTACTGCCAACCTGGACCGGT
CGAATGATAAGGTGTACGAGAATGTGACGGGCCTGGTGAAAGCTGTCATCGAGATGTCCAGTAAAATCCAGCCAGCCCCACCAGAGGAGT
ATGTCCCTATGGTGAAGGAAGTCGGCTTGGCCCTGAGGACATTATTGGCCACTGTGGATGAGACCATTCCCCTCCTACCAGCCAGCACCC
ACCGAGAGATTGAGATGGCACAGAAGCTATTGAACTCTGACCTGGGTGAGCTCATCAACAAGATGAAACTGGCCCAGCAGTATGTCATGA
CCAGCCTCCAGCAAGAGTACAAAAAGCAAATGCTGACTGCTGCTCACGCCCTGGCTGTGGATGCCAAAAACTTACTCGATGTCATTGACC
AAGCAAGACTGAAAATGCTTGGGCAGACGAGACCACACTGAGCCTCCCCTAGGAGCACGTCTTGCTACCCTCTTTTGAAGATGTTCTCTA
GCCTTCCACCAGCAGCGAGGAATTAACCCTGTGTCCTCAGTCGCCAGCACTTACAGCTCCAACTTTTTTGAATGACCATCTGGTTGAAAA
ATCTTTCTCATATAAGTTTAACCACACTTTGATTTGGGTTCATTTTTTGTTTTGTTTTTTTCAATCATGATATTCAGAAAAATCCAGGAT
CCAAAATGTGGCGTTTTTCTAAGAATGAAAATTATATGTAAGCTTTTAAGCATCATGAAGAACAATTTATGTTCACATTAAGATACGTTC
TAAAGGGGGATGGCCAAGGGGTGACATCTTAATTCCTAAACTACCTTAGCTGCATAGTGGAAGAGGAGAGCATGAAGCAAAGAATTCCAG
GAAACCCAAGAGGCTGAGAATTCTTTTGTCTACCATAGAATTATTATCCAGACTGGAATTTTTGTTTGTTAGAACACCCTTCAGTTGCAA
TATGCTAATCCCACTTTACAAAGAATATAAAAGCTATATTTTGAAGACTTGAGTTATTTCAGAAAAAACTACAGCCCTTTTTGTCTTACC
TGCCTTTTACTTTCGTGTGGATATGTGAAGCATTGGGTCGGGAACTAGCTGTAGAACACAACTAAAAACTCATGTCTTTTTTCACAGAAT
AATGTGCCAGTTTTTTGTAGCAATGTTATTTCTCTTGGAAGCAGAAATGCTTTGTACCAGAGCACCTCCAAACTGCATTGAGGAGAAGTT
CCAGAACCATCCCCTTTTTCCATTTTTATATAATTTATAAAGAAAGATTAAAGCCATGTTGACTATTTTACAGCCACTGGAGTTAACTAA
CCCTTCCTTGTATCTGTCTTCCCAGGAGAGAATGAAGCAAAACAGGAATTTGGTTTTCTTTTGATGTCCAGTTACACCATCCATTCTGTT
AATTTTGAAAAAATATACCCTCCCTTTAGTTTGTTGGGGGATATAAATTATTCTCAGGAAGAATATAATGAACTGTACAGTTACTTTGAC

>2913_2913_17_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000535192_length(amino acids)=558AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGP
IGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQP
APPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNL

--------------------------------------------------------------
>2913_2913_18_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000538769_length(transcript)=2950nt_BP=62nt
CGGCCGCCCCTCGGCCCCGGAGCCCCTCGGCGGCGCCACCATGTACTCGGGAGCCGGCCCCGGAGAATCCAGCTTTGGCGGTTGCAATTA
AAACATGTAAAAACTGTACTTCGGACAGCGTGAGAGAGAAATTTCTTCAAGAAGCCTTAACAATGCGTCAGTTTGACCATCCTCATATTG
TGAAGCTGATTGGAGTCATCACAGAGAATCCTGTCTGGATAATCATGGAGCTGTGCACACTTGGAGAGCTGAGGTCATTTTTGCAAGTAA
GGAAATACAGTTTGGATCTAGCATCTTTGATCCTGTATGCCTATCAGCTTAGTACAGCTCTTGCATATCTAGAGAGCAAAAGATTTGTAC
ACAGGGACATTGCTGCTCGGAATGTTCTGGTGTCCTCAAATGATTGTGTAAAATTAGGAGACTTTGGATTATCCCGATATATGGAAGATA
GTACTTACTACAAAGCTTCCAAAGGAAAATTGCCTATTAAATGGATGGCTCCAGAGTCAATCAATTTTCGACGTTTTACCTCAGCTAGTG
ACGTATGGATGTTTGGTGTGTGTATGTGGGAGATACTGATGCATGGTGTGAAGCCTTTTCAAGGAGTGAAGAACAATGATGTAATCGGTC
GAATTGAAAATGGGGAAAGATTACCAATGCCTCCAAATTGTCCTCCTACCCTCTACAGCCTTATGACGAAATGCTGGGCCTATGACCCCA
GCAGGCGGCCCAGGTTTACTGAACTTAAAGCTCAGCTCAGCACAATCCTGGAGGAAGAGAAGGCTCAGCAAGAAGAGCGCATGAGGATGG
AGTCCAGAAGACAGGCCACAGTGTCCTGGGACTCCGGAGGGTCTGATGAAGCACCGCCCAAGCCCAGCAGACCGGGTTATCCCAGTCCGA
GGTCCAGCGAAGGATTTTATCCCAGCCCACAGCACATGGTACAAACCAATCATTACCAGGTTTCTGGCTACCCTGGTTCACATGGAATCA
CAGCCATGGCTGGCAGCATCTATCCAGGTCAGGCATCTCTTTTGGACCAAACAGATTCATGGAATCATAGACCTCAGGAGATAGCAATGT
GGCAGCCCAATGTGGAGGACTCTACAGTATTGGACCTGCGAGGGATTGGGCAAGTGTTGCCAACCCATCTGATGGAAGAGCGTCTAATCC
GACAGCAACAGGAAATGGAAGAAGATCAGCGCTGGCTGGAAAAAGAGGAAAGATTTCTGAAACCTGATGTGAGACTCTCTCGAGGCAGTA
TTGACAGGGAGGATGGAAGTCTTCAGGGTCCGATTGGAAACCAACATATATATCAGCCTGTGGGTAAACCAGATCCTGCAGCTCCACCAA
AGAAACCGCCTCGCCCTGGAGCTCCCGGTCATCTGGGAAGCCTTGCCAGCCTCAGCAGCCCTGCTGACAGCTACAACGAGGGTGTCAAGC
TTCAGCCCCAGGAAATCAGCCCCCCTCCTACTGCCAACCTGGACCGGTCGAATGATAAGGTGTACGAGAATGTGACGGGCCTGGTGAAAG
CTGTCATCGAGATGTCCAGTAAAATCCAGCCAGCCCCACCAGAGGAGTATGTCCCTATGGTGAAGGAAGTCGGCTTGGCCCTGAGGACAT
TATTGGCCACTGTGGATGAGACCATTCCCCTCCTACCAGCCAGCACCCACCGAGAGATTGAGATGGCACAGAAGCTATTGAACTCTGACC
TGGGTGAGCTCATCAACAAGATGAAACTGGCCCAGCAGTATGTCATGACCAGCCTCCAGCAAGAGTACAAAAAGCAAATGCTGACTGCTG
CTCACGCCCTGGCTGTGGATGCCAAAAACTTACTCGATGTCATTGACCAAGCAAGACTGAAAATGCTTGGGCAGACGAGACCACACTGAG
CCTCCCCTAGGAGCACGTCTTGCTACCCTCTTTTGAAGATGTTCTCTAGCCTTCCACCAGCAGCGAGGAATTAACCCTGTGTCCTCAGTC
GCCAGCACTTACAGCTCCAACTTTTTTGAATGACCATCTGGTTGAAAAATCTTTCTCATATAAGTTTAACCACACTTTGATTTGGGTTCA
TTTTTTGTTTTGTTTTTTTCAATCATGATATTCAGAAAAATCCAGGATCCAAAATGTGGCGTTTTTCTAAGAATGAAAATTATATGTAAG
CTTTTAAGCATCATGAAGAACAATTTATGTTCACATTAAGATACGTTCTAAAGGGGGATGGCCAAGGGGTGACATCTTAATTCCTAAACT
ACCTTAGCTGCATAGTGGAAGAGGAGAGCATGAAGCAAAGAATTCCAGGAAACCCAAGAGGCTGAGAATTCTTTTGTCTACCATAGAATT
ATTATCCAGACTGGAATTTTTGTTTGTTAGAACACCCTTCAGTTGCAATATGCTAATCCCACTTTACAAAGAATATAAAAGCTATATTTT
GAAGACTTGAGTTATTTCAGAAAAAACTACAGCCCTTTTTGTCTTACCTGCCTTTTACTTTCGTGTGGATATGTGAAGCATTGGGTCGGG
AACTAGCTGTAGAACACAACTAAAAACTCATGTCTTTTTTCACAGAATAATGTGCCAGTTTTTTGTAGCAATGTTATTTCTCTTGGAAGC
AGAAATGCTTTGTACCAGAGCACCTCCAAACTGCATTGAGGAGAAGTTCCAGAACCATCCCCTTTTTCCATTTTTATATAATTTATAAAG
AAAGATTAAAGCCATGTTGACTATTTTACAGCCACTGGAGTTAACTAACCCTTCCTTGTATCTGTCTTCCCAGGAGAGAATGAAGCAAAA
CAGGAATTTGGTTTTCTTTTGATGTCCAGTTACACCATCCATTCTGTTAATTTTGAAAAAATATACCCTCCCTTTAGTTTGTTGGGGGAT

>2913_2913_18_AGO2-PTK2_AGO2_chr8_141645584_ENST00000519980_PTK2_chr8_141762415_ENST00000538769_length(amino acids)=604AA_BP=
MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE
SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN
NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRP
GYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLM
EERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSY
NEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQK

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for EIF2C2-PTK2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgenePTK2chr8:141645584chr8:141678523ENST000005210592832912_1052903.01053.0ARHGEF28
TgenePTK2chr8:141645584chr8:141678523ENST000005226842832912_1052903.01053.0ARHGEF28
TgenePTK2chr8:141645584chr8:141685598ENST000003409302633912_1052854.01066.0ARHGEF28
TgenePTK2chr8:141645584chr8:141685598ENST000005210592632912_1052854.01053.0ARHGEF28
TgenePTK2chr8:141645584chr8:141685598ENST000005226842632912_1052854.01053.0ARHGEF28
TgenePTK2chr8:141645584chr8:141712806ENST000003409302333912_1052743.01066.0ARHGEF28
TgenePTK2chr8:141645584chr8:141712806ENST000005210592332912_1052743.01053.0ARHGEF28
TgenePTK2chr8:141645584chr8:141712806ENST000005226842332912_1052743.01053.0ARHGEF28
TgenePTK2chr8:141645584chr8:141762415ENST000003409301533912_1052444.01066.0ARHGEF28
TgenePTK2chr8:141645584chr8:141762415ENST000005210591532912_1052444.01053.0ARHGEF28
TgenePTK2chr8:141645584chr8:141762415ENST000005226841532912_1052444.01053.0ARHGEF28


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneAGO2chr8:141645584chr8:141669777ENST00000220592-119311_3167.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141669777ENST00000220592-119524_5667.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141669777ENST00000220592-119709_7107.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141669777ENST00000220592-119753_7617.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141669777ENST00000220592-119790_8127.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141669777ENST00000519980-118311_3167.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141669777ENST00000519980-118524_5667.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141669777ENST00000519980-118709_7107.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141669777ENST00000519980-118753_7617.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141669777ENST00000519980-118790_8127.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141675096ENST00000220592-119311_3167.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141675096ENST00000220592-119524_5667.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141675096ENST00000220592-119709_7107.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141675096ENST00000220592-119753_7617.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141675096ENST00000220592-119790_8127.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141675096ENST00000519980-118311_3167.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141675096ENST00000519980-118524_5667.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141675096ENST00000519980-118709_7107.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141675096ENST00000519980-118753_7617.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141675096ENST00000519980-118790_8127.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141678523ENST00000220592-119311_3167.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141678523ENST00000220592-119524_5667.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141678523ENST00000220592-119709_7107.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141678523ENST00000220592-119753_7617.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141678523ENST00000220592-119790_8127.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141678523ENST00000519980-118311_3167.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141678523ENST00000519980-118524_5667.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141678523ENST00000519980-118709_7107.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141678523ENST00000519980-118753_7617.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141678523ENST00000519980-118790_8127.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141685598ENST00000220592-119311_3167.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141685598ENST00000220592-119524_5667.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141685598ENST00000220592-119709_7107.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141685598ENST00000220592-119753_7617.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141685598ENST00000220592-119790_8127.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141685598ENST00000519980-118311_3167.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141685598ENST00000519980-118524_5667.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141685598ENST00000519980-118709_7107.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141685598ENST00000519980-118753_7617.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141685598ENST00000519980-118790_8127.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141712806ENST00000220592-119311_3167.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141712806ENST00000220592-119524_5667.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141712806ENST00000220592-119709_7107.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141712806ENST00000220592-119753_7617.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141712806ENST00000220592-119790_8127.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141712806ENST00000519980-118311_3167.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141712806ENST00000519980-118524_5667.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141712806ENST00000519980-118709_7107.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141712806ENST00000519980-118753_7617.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141712806ENST00000519980-118790_8127.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141762415ENST00000220592-119311_3167.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141762415ENST00000220592-119524_5667.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141762415ENST00000220592-119709_7107.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141762415ENST00000220592-119753_7617.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141762415ENST00000220592-119790_8127.333333333333333860.0guide RNA
HgeneAGO2chr8:141645584chr8:141762415ENST00000519980-118311_3167.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141762415ENST00000519980-118524_5667.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141762415ENST00000519980-118709_7107.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141762415ENST00000519980-118753_7617.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141762415ENST00000519980-118790_8127.333333333333333826.0guide RNA
HgeneAGO2chr8:141645584chr8:141669777ENST00000220592-119587_5907.333333333333333860.0GW182 family members
HgeneAGO2chr8:141645584chr8:141669777ENST00000220592-119650_6607.333333333333333860.0GW182 family members
HgeneAGO2chr8:141645584chr8:141669777ENST00000519980-118587_5907.333333333333333826.0GW182 family members
HgeneAGO2chr8:141645584chr8:141669777ENST00000519980-118650_6607.333333333333333826.0GW182 family members
HgeneAGO2chr8:141645584chr8:141675096ENST00000220592-119587_5907.333333333333333860.0GW182 family members
HgeneAGO2chr8:141645584chr8:141675096ENST00000220592-119650_6607.333333333333333860.0GW182 family members
HgeneAGO2chr8:141645584chr8:141675096ENST00000519980-118587_5907.333333333333333826.0GW182 family members
HgeneAGO2chr8:141645584chr8:141675096ENST00000519980-118650_6607.333333333333333826.0GW182 family members
HgeneAGO2chr8:141645584chr8:141678523ENST00000220592-119587_5907.333333333333333860.0GW182 family members
HgeneAGO2chr8:141645584chr8:141678523ENST00000220592-119650_6607.333333333333333860.0GW182 family members
HgeneAGO2chr8:141645584chr8:141678523ENST00000519980-118587_5907.333333333333333826.0GW182 family members
HgeneAGO2chr8:141645584chr8:141678523ENST00000519980-118650_6607.333333333333333826.0GW182 family members
HgeneAGO2chr8:141645584chr8:141685598ENST00000220592-119587_5907.333333333333333860.0GW182 family members
HgeneAGO2chr8:141645584chr8:141685598ENST00000220592-119650_6607.333333333333333860.0GW182 family members
HgeneAGO2chr8:141645584chr8:141685598ENST00000519980-118587_5907.333333333333333826.0GW182 family members
HgeneAGO2chr8:141645584chr8:141685598ENST00000519980-118650_6607.333333333333333826.0GW182 family members
HgeneAGO2chr8:141645584chr8:141712806ENST00000220592-119587_5907.333333333333333860.0GW182 family members
HgeneAGO2chr8:141645584chr8:141712806ENST00000220592-119650_6607.333333333333333860.0GW182 family members
HgeneAGO2chr8:141645584chr8:141712806ENST00000519980-118587_5907.333333333333333826.0GW182 family members
HgeneAGO2chr8:141645584chr8:141712806ENST00000519980-118650_6607.333333333333333826.0GW182 family members
HgeneAGO2chr8:141645584chr8:141762415ENST00000220592-119587_5907.333333333333333860.0GW182 family members
HgeneAGO2chr8:141645584chr8:141762415ENST00000220592-119650_6607.333333333333333860.0GW182 family members
HgeneAGO2chr8:141645584chr8:141762415ENST00000519980-118587_5907.333333333333333826.0GW182 family members
HgeneAGO2chr8:141645584chr8:141762415ENST00000519980-118650_6607.333333333333333826.0GW182 family members
TgenePTK2chr8:141645584chr8:141669777ENST000003409303133912_1052995.01066.0ARHGEF28
TgenePTK2chr8:141645584chr8:141669777ENST000005210593032912_1052982.01053.0ARHGEF28
TgenePTK2chr8:141645584chr8:141669777ENST000005226843032912_1052982.01053.0ARHGEF28
TgenePTK2chr8:141645584chr8:141675096ENST000003409303033912_1052968.01066.0ARHGEF28
TgenePTK2chr8:141645584chr8:141675096ENST000005210592932912_1052955.01053.0ARHGEF28
TgenePTK2chr8:141645584chr8:141675096ENST000005226842932912_1052955.01053.0ARHGEF28
TgenePTK2chr8:141645584chr8:141678523ENST000003409302933912_1052916.01066.0ARHGEF28


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EIF2C2-PTK2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for EIF2C2-PTK2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneAGO2C0001973Alcoholic Intoxication, Chronic1PSYGENET
HgeneAGO2C0009171Cocaine Abuse1CTD_human
HgeneAGO2C0023466Leukemia, Monocytic, Chronic1CTD_human
HgeneAGO2C0023470Myeloid Leukemia1CTD_human
HgeneAGO2C0236736Cocaine-Related Disorders1CTD_human
HgeneAGO2C0345967Malignant mesothelioma1CTD_human
HgeneAGO2C0600427Cocaine Dependence1CTD_human
TgeneC0004238Atrial Fibrillation2CTD_human
TgeneC0007137Squamous cell carcinoma2CTD_human
TgeneC0027626Neoplasm Invasiveness2CTD_human
TgeneC0235480Paroxysmal atrial fibrillation2CTD_human
TgeneC2585653Persistent atrial fibrillation2CTD_human
TgeneC3468561familial atrial fibrillation2CTD_human
TgeneC0003873Rheumatoid Arthritis1CTD_human
TgeneC0007621Neoplastic Cell Transformation1CTD_human
TgeneC0017636Glioblastoma1CTD_human
TgeneC0024668Mammary Neoplasms, Experimental1CTD_human
TgeneC0026640Mouth Neoplasms1CTD_human
TgeneC0153381Malignant neoplasm of mouth1CTD_human
TgeneC0334588Giant Cell Glioblastoma1CTD_human
TgeneC1621958Glioblastoma Multiforme1CTD_human;UNIPROT
TgeneC2239176Liver carcinoma1CTD_human