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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ANKRD52-ASPHD1 (FusionGDB2 ID:HG283373TG253982)

Fusion Gene Summary for ANKRD52-ASPHD1

check button Fusion gene summary
Fusion gene informationFusion gene name: ANKRD52-ASPHD1
Fusion gene ID: hg283373tg253982
HgeneTgene
Gene symbol

ANKRD52

ASPHD1

Gene ID

283373

253982

Gene nameankyrin repeat domain 52aspartate beta-hydroxylase domain containing 1
SynonymsANKRD33-
Cytomap('ANKRD52')('ASPHD1')

12q13.3

16p11.2

Type of geneprotein-codingprotein-coding
Descriptionserine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit CCVWG5837PP6-ARS-Cankyrin repeat domain 33ankyrin repeat domain-containing protein 52protein phosphatase 6 ankyrin repeat subunit Cserine/threonine-protein phosphatase 6 regulaaspartate beta-hydroxylase domain-containing protein 1
Modification date2020031320200313
UniProtAcc

Q8NB46

Q5U4P2

Ensembl transtripts involved in fusion geneENST00000267116, ENST00000548241, 
Fusion gene scores* DoF score12 X 13 X 5=7806 X 5 X 3=90
# samples 115
** MAII scorelog2(11/780*10)=-2.82597060022495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(5/90*10)=-0.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANKRD52 [Title/Abstract] AND ASPHD1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANKRD52(56649568)-ASPHD1(29917109), # samples:3
Anticipated loss of major functional domain due to fusion event.ANKRD52-ASPHD1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ANKRD52-ASPHD1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ANKRD52 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ASPHD1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-MX-A666-01AANKRD52chr12

56649568

-ASPHD1chr16

29917109

+
ChimerDB4STADTCGA-MX-A666-01AANKRD52chr12

56650799

-ASPHD1chr16

29917109

+


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Fusion Gene ORF analysis for ANKRD52-ASPHD1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000267116ENST00000308748ANKRD52chr12

56649568

-ASPHD1chr16

29917109

+
In-frameENST00000267116ENST00000308748ANKRD52chr12

56650799

-ASPHD1chr16

29917109

+
In-frameENST00000267116ENST00000483405ANKRD52chr12

56649568

-ASPHD1chr16

29917109

+
In-frameENST00000267116ENST00000483405ANKRD52chr12

56650799

-ASPHD1chr16

29917109

+
intron-3CDSENST00000548241ENST00000308748ANKRD52chr12

56649568

-ASPHD1chr16

29917109

+
intron-3CDSENST00000548241ENST00000308748ANKRD52chr12

56650799

-ASPHD1chr16

29917109

+
intron-3CDSENST00000548241ENST00000483405ANKRD52chr12

56649568

-ASPHD1chr16

29917109

+
intron-3CDSENST00000548241ENST00000483405ANKRD52chr12

56650799

-ASPHD1chr16

29917109

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000267116ANKRD52chr1256649568-ENST00000483405ASPHD1chr1629917109+85358444826260
ENST00000267116ANKRD52chr1256649568-ENST00000308748ASPHD1chr1629917109+85358444826260
ENST00000267116ANKRD52chr1256650799-ENST00000483405ASPHD1chr1629917109+65238344625193
ENST00000267116ANKRD52chr1256650799-ENST00000308748ASPHD1chr1629917109+65238344625193

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000267116ENST00000483405ANKRD52chr1256649568-ASPHD1chr1629917109+0.0697130.930287
ENST00000267116ENST00000308748ANKRD52chr1256649568-ASPHD1chr1629917109+0.0697130.930287
ENST00000267116ENST00000483405ANKRD52chr1256650799-ASPHD1chr1629917109+0.106022590.89397746
ENST00000267116ENST00000308748ANKRD52chr1256650799-ASPHD1chr1629917109+0.106022590.89397746

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Fusion Genomic Features for ANKRD52-ASPHD1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ANKRD52chr1256650798-ASPHD1chr1629917108+0.0016282210.9983718
ANKRD52chr1256649567-ASPHD1chr1629917108+0.0008119110.9991881
ANKRD52chr1256650798-ASPHD1chr1629917108+0.0016282210.9983718
ANKRD52chr1256649567-ASPHD1chr1629917108+0.0008119110.9991881

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ANKRD52-ASPHD1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:56649568/chr16:29917109)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ANKRD52

Q8NB46

ASPHD1

Q5U4P2

FUNCTION: Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528106_1351541077.0RepeatNote=ANK 4
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-52840_691541077.0RepeatNote=ANK 2
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-52873_1021541077.0RepeatNote=ANK 3
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-5287_361541077.0RepeatNote=ANK 1
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-42840_69871077.0RepeatNote=ANK 2
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-4287_36871077.0RepeatNote=ANK 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528139_1681541077.0RepeatNote=ANK 5
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528172_2011541077.0RepeatNote=ANK 6
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528205_2341541077.0RepeatNote=ANK 7
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528238_2671541077.0RepeatNote=ANK 8
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528271_3011541077.0RepeatNote=ANK 9
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528305_3341541077.0RepeatNote=ANK 10
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528338_3671541077.0RepeatNote=ANK 11
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528371_4001541077.0RepeatNote=ANK 12
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528422_4511541077.0RepeatNote=ANK 13
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528455_4841541077.0RepeatNote=ANK 14
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528488_5451541077.0RepeatNote=ANK 15
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528549_5791541077.0RepeatNote=ANK 16
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528584_6131541077.0RepeatNote=ANK 17
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528617_6461541077.0RepeatNote=ANK 18
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528651_6801541077.0RepeatNote=ANK 19
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528687_7161541077.0RepeatNote=ANK 20
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528720_7491541077.0RepeatNote=ANK 21
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528753_7821541077.0RepeatNote=ANK 22
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528790_8191541077.0RepeatNote=ANK 23
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528822_8521541077.0RepeatNote=ANK 24
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528857_8861541077.0RepeatNote=ANK 25
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528890_9201541077.0RepeatNote=ANK 26
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528924_9531541077.0RepeatNote=ANK 27
HgeneANKRD52chr12:56649568chr16:29917109ENST00000267116-528960_9891541077.0RepeatNote=ANK 28
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428106_135871077.0RepeatNote=ANK 4
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428139_168871077.0RepeatNote=ANK 5
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428172_201871077.0RepeatNote=ANK 6
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428205_234871077.0RepeatNote=ANK 7
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428238_267871077.0RepeatNote=ANK 8
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428271_301871077.0RepeatNote=ANK 9
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428305_334871077.0RepeatNote=ANK 10
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428338_367871077.0RepeatNote=ANK 11
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428371_400871077.0RepeatNote=ANK 12
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428422_451871077.0RepeatNote=ANK 13
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428455_484871077.0RepeatNote=ANK 14
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428488_545871077.0RepeatNote=ANK 15
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428549_579871077.0RepeatNote=ANK 16
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428584_613871077.0RepeatNote=ANK 17
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428617_646871077.0RepeatNote=ANK 18
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428651_680871077.0RepeatNote=ANK 19
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428687_716871077.0RepeatNote=ANK 20
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428720_749871077.0RepeatNote=ANK 21
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-42873_102871077.0RepeatNote=ANK 3
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428753_782871077.0RepeatNote=ANK 22
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428790_819871077.0RepeatNote=ANK 23
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428822_852871077.0RepeatNote=ANK 24
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428857_886871077.0RepeatNote=ANK 25
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428890_920871077.0RepeatNote=ANK 26
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428924_953871077.0RepeatNote=ANK 27
HgeneANKRD52chr12:56650799chr16:29917109ENST00000267116-428960_989871077.0RepeatNote=ANK 28
TgeneASPHD1chr12:56649568chr16:29917109ENST0000030874813107_188354391.0Compositional biasNote=Gly-rich
TgeneASPHD1chr12:56650799chr16:29917109ENST0000030874813107_188354391.0Compositional biasNote=Gly-rich
TgeneASPHD1chr12:56649568chr16:29917109ENST00000308748131_72354391.0Topological domainCytoplasmic
TgeneASPHD1chr12:56649568chr16:29917109ENST000003087481396_390354391.0Topological domainLumenal
TgeneASPHD1chr12:56650799chr16:29917109ENST00000308748131_72354391.0Topological domainCytoplasmic
TgeneASPHD1chr12:56650799chr16:29917109ENST000003087481396_390354391.0Topological domainLumenal
TgeneASPHD1chr12:56649568chr16:29917109ENST000003087481373_95354391.0TransmembraneHelical
TgeneASPHD1chr12:56650799chr16:29917109ENST000003087481373_95354391.0TransmembraneHelical


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Fusion Gene Sequence for ANKRD52-ASPHD1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>4761_4761_1_ANKRD52-ASPHD1_ANKRD52_chr12_56649568_ENST00000267116_ASPHD1_chr16_29917109_ENST00000308748_length(transcript)=853nt_BP=584nt
AGGCGGGGCCGCGCTCTCCCTGCAGCCGCCACCGCAGCCGCCGCCTGGGCCGCTCCGTGTCCCCGGTGGAGCCGCCGCCGCCGCCGCCGG
GAGCTCGATGCGGACGGAGCCCGGGCCGAGCCATGGGGATCCTCAGCATCACGGACCAGCCGCCCCTGGTCCAGGCCATCTTTAGCCGAG
ATGTGGAGGAAGTGCGTTCCCTACTCTCGCAGAAGGAGAACATCAATGTGCTGGACCAAGAGAGGCGAACTCCATTGCATGCTGCTGCCT
ACGTAGGCGATGTCCCCATCCTCCAGTTGCTACTGATGTCAGGTGCTAATGTCAATGCTAAGGACACACTGTGGCTGACCCCTCTTCATC
GTGCTGCTGCCTCCCGAAACGAGAAGGTGCTGGGGCTGCTGCTGGCACATTCAGCAGATGTGAATGCCCGGGACAAGCTGTGGCAGACAC
CACTGCATGTGGCTGCTGCCAACCGGGCCACCAAGTGTGCTGAGGCTCTGGCACCCCTGTTGAGCAGCCTCAACGTGGCTGACAGGAGCG
GGCGCAGTGCTCTGCACCATGCAGTGCATAGTGGGCATCTTGAGGCTCCCCCGAAGATGGGCCTCGAGTGGTCTTCATCGTGGACCTCTG
GCACCCCAACGTGGCAGGGGCTGAGCGCCAGGCCCTCGACTTTGTCTTCGCCCCAGACCCTTGAAGGAAGGTGCTCCCTTCACACACCCA
GGCTGGAGAGACACTGCGCTCAGGGACGGCTTGATGGTAGCCAGGACCTCCTCTCTACTGCGGGGGTGGGCGGGGGCGGAGGATGGGAAC

>4761_4761_1_ANKRD52-ASPHD1_ANKRD52_chr12_56649568_ENST00000267116_ASPHD1_chr16_29917109_ENST00000308748_length(amino acids)=260AA_BP=180
MGRSVSPVEPPPPPPGARCGRSPGRAMGILSITDQPPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSG
ANVNAKDTLWLTPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLE

--------------------------------------------------------------
>4761_4761_2_ANKRD52-ASPHD1_ANKRD52_chr12_56649568_ENST00000267116_ASPHD1_chr16_29917109_ENST00000483405_length(transcript)=853nt_BP=584nt
AGGCGGGGCCGCGCTCTCCCTGCAGCCGCCACCGCAGCCGCCGCCTGGGCCGCTCCGTGTCCCCGGTGGAGCCGCCGCCGCCGCCGCCGG
GAGCTCGATGCGGACGGAGCCCGGGCCGAGCCATGGGGATCCTCAGCATCACGGACCAGCCGCCCCTGGTCCAGGCCATCTTTAGCCGAG
ATGTGGAGGAAGTGCGTTCCCTACTCTCGCAGAAGGAGAACATCAATGTGCTGGACCAAGAGAGGCGAACTCCATTGCATGCTGCTGCCT
ACGTAGGCGATGTCCCCATCCTCCAGTTGCTACTGATGTCAGGTGCTAATGTCAATGCTAAGGACACACTGTGGCTGACCCCTCTTCATC
GTGCTGCTGCCTCCCGAAACGAGAAGGTGCTGGGGCTGCTGCTGGCACATTCAGCAGATGTGAATGCCCGGGACAAGCTGTGGCAGACAC
CACTGCATGTGGCTGCTGCCAACCGGGCCACCAAGTGTGCTGAGGCTCTGGCACCCCTGTTGAGCAGCCTCAACGTGGCTGACAGGAGCG
GGCGCAGTGCTCTGCACCATGCAGTGCATAGTGGGCATCTTGAGGCTCCCCCGAAGATGGGCCTCGAGTGGTCTTCATCGTGGACCTCTG
GCACCCCAACGTGGCAGGGGCTGAGCGCCAGGCCCTCGACTTTGTCTTCGCCCCAGACCCTTGAAGGAAGGTGCTCCCTTCACACACCCA
GGCTGGAGAGACACTGCGCTCAGGGACGGCTTGATGGTAGCCAGGACCTCCTCTCTACTGCGGGGGTGGGCGGGGGCGGAGGATGGGAAC

>4761_4761_2_ANKRD52-ASPHD1_ANKRD52_chr12_56649568_ENST00000267116_ASPHD1_chr16_29917109_ENST00000483405_length(amino acids)=260AA_BP=180
MGRSVSPVEPPPPPPGARCGRSPGRAMGILSITDQPPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSG
ANVNAKDTLWLTPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLE

--------------------------------------------------------------
>4761_4761_3_ANKRD52-ASPHD1_ANKRD52_chr12_56650799_ENST00000267116_ASPHD1_chr16_29917109_ENST00000308748_length(transcript)=652nt_BP=383nt
AGGCGGGGCCGCGCTCTCCCTGCAGCCGCCACCGCAGCCGCCGCCTGGGCCGCTCCGTGTCCCCGGTGGAGCCGCCGCCGCCGCCGCCGG
GAGCTCGATGCGGACGGAGCCCGGGCCGAGCCATGGGGATCCTCAGCATCACGGACCAGCCGCCCCTGGTCCAGGCCATCTTTAGCCGAG
ATGTGGAGGAAGTGCGTTCCCTACTCTCGCAGAAGGAGAACATCAATGTGCTGGACCAAGAGAGGCGAACTCCATTGCATGCTGCTGCCT
ACGTAGGCGATGTCCCCATCCTCCAGTTGCTACTGATGTCAGGTGCTAATGTCAATGCTAAGGACACACTGTGGCTGACCCCTCTTCATC
GTGCTGCTGCCTCCCGAAACGAGGCTCCCCCGAAGATGGGCCTCGAGTGGTCTTCATCGTGGACCTCTGGCACCCCAACGTGGCAGGGGC
TGAGCGCCAGGCCCTCGACTTTGTCTTCGCCCCAGACCCTTGAAGGAAGGTGCTCCCTTCACACACCCAGGCTGGAGAGACACTGCGCTC
AGGGACGGCTTGATGGTAGCCAGGACCTCCTCTCTACTGCGGGGGTGGGCGGGGGCGGAGGATGGGAACTGGCTAGTGAGCACTGAAATA

>4761_4761_3_ANKRD52-ASPHD1_ANKRD52_chr12_56650799_ENST00000267116_ASPHD1_chr16_29917109_ENST00000308748_length(amino acids)=193AA_BP=113
MGRSVSPVEPPPPPPGARCGRSPGRAMGILSITDQPPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSG
ANVNAKDTLWLTPLHRAAASRNEAPPKMGLEWSSSWTSGTPTWQGLSARPSTLSSPQTLEGRCSLHTPRLERHCAQGRLDGSQDLLSTAG

--------------------------------------------------------------
>4761_4761_4_ANKRD52-ASPHD1_ANKRD52_chr12_56650799_ENST00000267116_ASPHD1_chr16_29917109_ENST00000483405_length(transcript)=652nt_BP=383nt
AGGCGGGGCCGCGCTCTCCCTGCAGCCGCCACCGCAGCCGCCGCCTGGGCCGCTCCGTGTCCCCGGTGGAGCCGCCGCCGCCGCCGCCGG
GAGCTCGATGCGGACGGAGCCCGGGCCGAGCCATGGGGATCCTCAGCATCACGGACCAGCCGCCCCTGGTCCAGGCCATCTTTAGCCGAG
ATGTGGAGGAAGTGCGTTCCCTACTCTCGCAGAAGGAGAACATCAATGTGCTGGACCAAGAGAGGCGAACTCCATTGCATGCTGCTGCCT
ACGTAGGCGATGTCCCCATCCTCCAGTTGCTACTGATGTCAGGTGCTAATGTCAATGCTAAGGACACACTGTGGCTGACCCCTCTTCATC
GTGCTGCTGCCTCCCGAAACGAGGCTCCCCCGAAGATGGGCCTCGAGTGGTCTTCATCGTGGACCTCTGGCACCCCAACGTGGCAGGGGC
TGAGCGCCAGGCCCTCGACTTTGTCTTCGCCCCAGACCCTTGAAGGAAGGTGCTCCCTTCACACACCCAGGCTGGAGAGACACTGCGCTC
AGGGACGGCTTGATGGTAGCCAGGACCTCCTCTCTACTGCGGGGGTGGGCGGGGGCGGAGGATGGGAACTGGCTAGTGAGCACTGAAATA

>4761_4761_4_ANKRD52-ASPHD1_ANKRD52_chr12_56650799_ENST00000267116_ASPHD1_chr16_29917109_ENST00000483405_length(amino acids)=193AA_BP=113
MGRSVSPVEPPPPPPGARCGRSPGRAMGILSITDQPPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSG
ANVNAKDTLWLTPLHRAAASRNEAPPKMGLEWSSSWTSGTPTWQGLSARPSTLSSPQTLEGRCSLHTPRLERHCAQGRLDGSQDLLSTAG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ANKRD52-ASPHD1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ANKRD52-ASPHD1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ANKRD52-ASPHD1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource