Fusion Gene Studies
in Kim Lab

FusionBase FusionGDB FusionGDB2 FusionPDB FusionNeoAntigen FusionAI FusionNW FGviewer Publication Contact
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:EOGT-SYNPR (FusionGDB2 ID:HG285203TG132204)

Fusion Gene Summary for EOGT-SYNPR

check button Fusion gene summary
Fusion gene informationFusion gene name: EOGT-SYNPR
Fusion gene ID: hg285203tg132204
HgeneTgene
Gene symbol

EOGT

SYNPR

Gene ID

285203

132204

Gene nameEGF domain specific O-linked N-acetylglucosamine transferasesynaptoporin
SynonymsAER61|AOS4|C3orf64|EOGT1SPO
Cytomap('C3orf64','EOGT')('SYNPR','SYNPR')

3p14.1

3p14.2

Type of geneprotein-codingprotein-coding
DescriptionEGF domain-specific O-linked N-acetylglucosamine transferaseAER61 glycosyltransferaseEGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferaseEGF-O-GlcNAc transferaseextracellular O-linked N-acetylglucosamine transferasesynaptoporin
Modification date2020032020200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000295571, ENST00000383701, 
ENST00000540764, ENST00000540955, 
Fusion gene scores* DoF score3 X 2 X 3=188 X 6 X 6=288
# samples 39
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(9/288*10)=-1.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EOGT [Title/Abstract] AND SYNPR [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointC3orf64(69047162)-SYNPR(63466508), # samples:1
EOGT(69047162)-SYNPR(63466508), # samples:1
Anticipated loss of major functional domain due to fusion event.EOGT-SYNPR seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
EOGT-SYNPR seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
EOGT-SYNPR seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
EOGT-SYNPR seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across EOGT (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across SYNPR (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4MESOTCGA-UT-A88C-01BC3orf64chr3

69047162

-SYNPRchr3

63466508

+
ChimerDB4MESOTCGA-UT-A88C-01BEOGTchr3

69047162

-SYNPRchr3

63466508

+


Top

Fusion Gene ORF analysis for EOGT-SYNPR

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000295571ENST00000460711EOGTchr3

69047162

-SYNPRchr3

63466508

+
5CDS-3UTRENST00000295571ENST00000465156EOGTchr3

69047162

-SYNPRchr3

63466508

+
5CDS-3UTRENST00000295571ENST00000478744EOGTchr3

69047162

-SYNPRchr3

63466508

+
5CDS-3UTRENST00000383701ENST00000460711EOGTchr3

69047162

-SYNPRchr3

63466508

+
5CDS-3UTRENST00000383701ENST00000465156EOGTchr3

69047162

-SYNPRchr3

63466508

+
5CDS-3UTRENST00000383701ENST00000478744EOGTchr3

69047162

-SYNPRchr3

63466508

+
5CDS-3UTRENST00000540764ENST00000460711EOGTchr3

69047162

-SYNPRchr3

63466508

+
5CDS-3UTRENST00000540764ENST00000465156EOGTchr3

69047162

-SYNPRchr3

63466508

+
5CDS-3UTRENST00000540764ENST00000478744EOGTchr3

69047162

-SYNPRchr3

63466508

+
In-frameENST00000295571ENST00000295894EOGTchr3

69047162

-SYNPRchr3

63466508

+
In-frameENST00000295571ENST00000478300EOGTchr3

69047162

-SYNPRchr3

63466508

+
In-frameENST00000295571ENST00000479198EOGTchr3

69047162

-SYNPRchr3

63466508

+
In-frameENST00000383701ENST00000295894EOGTchr3

69047162

-SYNPRchr3

63466508

+
In-frameENST00000383701ENST00000478300EOGTchr3

69047162

-SYNPRchr3

63466508

+
In-frameENST00000383701ENST00000479198EOGTchr3

69047162

-SYNPRchr3

63466508

+
In-frameENST00000540764ENST00000295894EOGTchr3

69047162

-SYNPRchr3

63466508

+
In-frameENST00000540764ENST00000478300EOGTchr3

69047162

-SYNPRchr3

63466508

+
In-frameENST00000540764ENST00000479198EOGTchr3

69047162

-SYNPRchr3

63466508

+
intron-3CDSENST00000540955ENST00000295894EOGTchr3

69047162

-SYNPRchr3

63466508

+
intron-3CDSENST00000540955ENST00000478300EOGTchr3

69047162

-SYNPRchr3

63466508

+
intron-3CDSENST00000540955ENST00000479198EOGTchr3

69047162

-SYNPRchr3

63466508

+
intron-3UTRENST00000540955ENST00000460711EOGTchr3

69047162

-SYNPRchr3

63466508

+
intron-3UTRENST00000540955ENST00000465156EOGTchr3

69047162

-SYNPRchr3

63466508

+
intron-3UTRENST00000540955ENST00000478744EOGTchr3

69047162

-SYNPRchr3

63466508

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000383701EOGTchr369047162-ENST00000478300SYNPRchr363466508+378815747042347547
ENST00000383701EOGTchr369047162-ENST00000295894SYNPRchr363466508+378815747042347547
ENST00000383701EOGTchr369047162-ENST00000479198SYNPRchr363466508+386815747042158484
ENST00000295571EOGTchr369047162-ENST00000478300SYNPRchr363466508+345012363662009547
ENST00000295571EOGTchr369047162-ENST00000295894SYNPRchr363466508+345012363662009547
ENST00000295571EOGTchr369047162-ENST00000479198SYNPRchr363466508+353012363661820484
ENST00000540764EOGTchr369047162-ENST00000478300SYNPRchr363466508+2837623951396433
ENST00000540764EOGTchr369047162-ENST00000295894SYNPRchr363466508+2837623951396433
ENST00000540764EOGTchr369047162-ENST00000479198SYNPRchr363466508+2917623951207370

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000383701ENST00000478300EOGTchr369047162-SYNPRchr363466508+0.0004135170.9995865
ENST00000383701ENST00000295894EOGTchr369047162-SYNPRchr363466508+0.0004135170.9995865
ENST00000383701ENST00000479198EOGTchr369047162-SYNPRchr363466508+0.0003507930.99964917
ENST00000295571ENST00000478300EOGTchr369047162-SYNPRchr363466508+0.0003643340.9996357
ENST00000295571ENST00000295894EOGTchr369047162-SYNPRchr363466508+0.0003643340.9996357
ENST00000295571ENST00000479198EOGTchr369047162-SYNPRchr363466508+0.0003162640.99968374
ENST00000540764ENST00000478300EOGTchr369047162-SYNPRchr363466508+0.000499240.99950075
ENST00000540764ENST00000295894EOGTchr369047162-SYNPRchr363466508+0.000499240.99950075
ENST00000540764ENST00000479198EOGTchr369047162-SYNPRchr363466508+0.000718030.99928194

Top

Fusion Genomic Features for EOGT-SYNPR


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
EOGTchr369047161-SYNPRchr363466507+0.0127558310.9872442
EOGTchr369047161-SYNPRchr363466507+0.0127558310.9872442

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for EOGT-SYNPR


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:69047162/chr3:63466508)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSYNPRchr3:69047162chr3:63466508ENST0000029589405210_2428266.0RegionNote=5 X approximate repeats
TgeneSYNPRchr3:69047162chr3:63466508ENST0000047830016210_24228286.0RegionNote=5 X approximate repeats
TgeneSYNPRchr3:69047162chr3:63466508ENST0000029589405210_2148266.0RepeatNote=1
TgeneSYNPRchr3:69047162chr3:63466508ENST0000029589405222_2268266.0RepeatNote=2
TgeneSYNPRchr3:69047162chr3:63466508ENST0000029589405227_2318266.0RepeatNote=3
TgeneSYNPRchr3:69047162chr3:63466508ENST0000029589405232_2368266.0RepeatNote=4
TgeneSYNPRchr3:69047162chr3:63466508ENST0000029589405238_2428266.0RepeatNote=5
TgeneSYNPRchr3:69047162chr3:63466508ENST0000047830016210_21428286.0RepeatNote=1
TgeneSYNPRchr3:69047162chr3:63466508ENST0000047830016222_22628286.0RepeatNote=2
TgeneSYNPRchr3:69047162chr3:63466508ENST0000047830016227_23128286.0RepeatNote=3
TgeneSYNPRchr3:69047162chr3:63466508ENST0000047830016232_23628286.0RepeatNote=4
TgeneSYNPRchr3:69047162chr3:63466508ENST0000047830016238_24228286.0RepeatNote=5
TgeneSYNPRchr3:69047162chr3:63466508ENST0000029589405103_1148266.0Topological domainCytoplasmic
TgeneSYNPRchr3:69047162chr3:63466508ENST0000029589405136_1778266.0Topological domainVesicular
TgeneSYNPRchr3:69047162chr3:63466508ENST0000029589405199_2658266.0Topological domainCytoplasmic
TgeneSYNPRchr3:69047162chr3:63466508ENST000002958940526_818266.0Topological domainVesicular
TgeneSYNPRchr3:69047162chr3:63466508ENST0000047830016103_11428286.0Topological domainCytoplasmic
TgeneSYNPRchr3:69047162chr3:63466508ENST0000047830016136_17728286.0Topological domainVesicular
TgeneSYNPRchr3:69047162chr3:63466508ENST0000047830016199_26528286.0Topological domainCytoplasmic
TgeneSYNPRchr3:69047162chr3:63466508ENST000004783001626_8128286.0Topological domainVesicular
TgeneSYNPRchr3:69047162chr3:63466508ENST0000029589405115_1358266.0TransmembraneHelical
TgeneSYNPRchr3:69047162chr3:63466508ENST0000029589405178_1988266.0TransmembraneHelical
TgeneSYNPRchr3:69047162chr3:63466508ENST00000295894055_258266.0TransmembraneHelical
TgeneSYNPRchr3:69047162chr3:63466508ENST000002958940582_1028266.0TransmembraneHelical
TgeneSYNPRchr3:69047162chr3:63466508ENST0000047830016115_13528286.0TransmembraneHelical
TgeneSYNPRchr3:69047162chr3:63466508ENST0000047830016178_19828286.0TransmembraneHelical
TgeneSYNPRchr3:69047162chr3:63466508ENST000004783001682_10228286.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEOGTchr3:69047162chr3:63466508ENST00000295571-1015524_527277444.0MotifPrevents secretion from ER
HgeneEOGTchr3:69047162chr3:63466508ENST00000383701-1018524_527277528.0MotifPrevents secretion from ER
TgeneSYNPRchr3:69047162chr3:63466508ENST00000295894051_2028266.0DomainMARVEL
TgeneSYNPRchr3:69047162chr3:63466508ENST00000478300161_20228286.0DomainMARVEL
TgeneSYNPRchr3:69047162chr3:63466508ENST00000295894051_48266.0Topological domainCytoplasmic
TgeneSYNPRchr3:69047162chr3:63466508ENST00000478300161_428286.0Topological domainCytoplasmic
TgeneSYNPRchr3:69047162chr3:63466508ENST00000478300165_2528286.0TransmembraneHelical


Top

Fusion Gene Sequence for EOGT-SYNPR


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>26737_26737_1_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000295571_SYNPR_chr3_63466508_ENST00000295894_length(transcript)=3450nt_BP=1236nt
GCCGTCTCCTCCGCCTCCTCCTCGGTAGTTCACGGCTGCCCCGGCTCCAGGCCTGTGGAAATCGAATCAAGGGTTTCTGGAGTGGAGTGA
TTCCAGCTGCTTTGAGCTGAAGGAAAAGTAGCCTGGCCAGTAAAGCGTCCGTGTGCTGGAGGAGTGCAGCCACCCATCCCGGCGGGCCTT
GCAGGACGACCGACACCAGGAAGGCTTTGTGCCAGGCCCAGCAGCCACCCCCAGCCGCCTTATGCAAGTGGGTACATGCCCTCGCCAGAC
GCCAGCTTTCTGATCTGCGTCTTTAGATTTTTTCCATCGCCTAAGCGTTACTTCTCCACTGATCGGTTTTAGAGACCTGAAACATCACAG
AAGCTTCTGAGTGGTTCTGAAGATTCAAGAGGTTTGCAGGTTGCTATGTTAATGTTGTTTGTCTTTGGAGTCTTACTTCATGAAGTCTCA
CTGAGTGGTCAGAATGAAGCTCCTCCTAATACTCACAGCATTCCAGGCGAACCTCTGTATAACTATGCCAGCATCCGCTTGCCAGAGGAG
CACATTCCCTTCTTTTTGCACAACAATAGGCATATTGCCACTGTCTGTAGGAAAGACTCTCTTTGTCCATATAAGAAACACCTAGAGAAG
CTAAAGTACTGCTGGGGTTATGAGAAATCCTGCAAACCAGAGTTCAGGTTTGGTTACCCAGTTTGCAGCTATGTCGACATGGGATGGACG
GACACTCTTGAGTCAGCTGAGGACATATTTTGGAAACAAGCTGACTTTGGATATGCCAGAGAGAGGCTGGAGGAGATGCATGTGCTCTGT
CAGCCTAAGGAAACGAGTGACTCAAGTCTGGTGTGTTCCCGTTATCTTCAGTACTGCAGAGCAACCAATCTCTATCTTGATTTAAGAAAC
ATCAAGAGAAATCATGACAGATTTAAGGAGGACTTTTTCCAGAGTGGTGAAATTGGAGGGCACTGTAAACTTGACATCCGTACATTGACG
TCTGAAGGTCAGCGCAAAAGCCCTCTGCAGTCATGGTTTGCTGAGCTACAAAGCTATACTCAGCTCAACTTCAGACCTATAGAAGATGCT
AAATGTGACATTGTCATTGAAAAACCAACATATTTCATGAAATTAGATGCAGGTGTTAACATGTATCACCACTTCTGTGATTTCATCAAT
CTTTATATTACTCAGCACGTTAATAACTCATTCAGTACTGACGTGTACATCGTGATGTGGGACACCCTTTTTGCAATCTTTGCATTTGCA
ACATGCGGTGGCTATTCTGGAGGCCTGCGGCTGAGTGTGGACTGCGTCAACAAGACAGAAAGTAACCTCAGCATCGACATAGCGTTTGCC
TACCCATTCAGGTTGCACCAGGTGACGTTTGAGGTGCCCACCTGCGAGGGAAAGGAACGGCAGAAGCTGGCATTGATTGGTGACTCCTCG
TCTTCAGCAGAGTTCTTCGTCACTGTTGCTGTCTTCGCCTTCCTCTACTCTTTGGCTGCCACTGTCGTTTACATTTTCTTCCAGAACAAA
TACCGGGAAAACAACCGGGGCCCACTCATTGACTTCATTGTCACTGTAGTCTTTTCGTTCTTGTGGTTGGTGGGTTCATCAGCTTGGGCA
AAAGGACTGTCTGACGTCAAAGTTGCAACGGATCCCAAGGAAGTATTGCTACTAATGTCAGCTTGCAAACAGCCATCCAACAAATGCATG
GCTATCCACAGCCCTGTTATGTCAAGCTTAAACACTTCTGTGGTCTTTGGATTCTTGAACTTTATTCTCTGGGCTGGAAACATATGGTTT
GTTTTCAAGGAGACCGGCTGGCATTCTTCGGGACAGAGATATCTTTCAGATCCAATGGAGAAGCACTCCAGCAGCTATAATCAAGGTGGT
TACAACCAAGACAGCTATGGATCAAGCAGTGGGTACAGTCAGCAGGCGAGTTTGGGGCCAACCTCAGATGAGTTTGGCCAACAGCCTACT
GGCCCCACTTCCTTTACCAATCAGATTTAACAGAGTAGCATTTGCATTCTTCTGCAGTCGCCTCACCATCTTCCATTTCAGTGGCAGAAG
AATTTTTTAAGGGTTTCAATCAATTATTAATGCAGAGAGTATTGAATGTAAATCAGAGCTCTCTAGTCTTCATTAAGGCAGCAAGTCCTG
GGTTGTGAAAAATGATACTTAGAGATGAGGCGACATGAGGAGATATATTATTCATCATAGATGGCTAATTGGAGAGTACCTTGTTATATA
TACAGATACTTTCATGGTCATTTTGTATGTATGTTAAAGTAGTAGAAGTATTTTGTAGCTTAAAGTCTCTAGTATGTAATATGCATAAAG
TAAATCAAATAGCGTTGAGTTTTCTTATGCATTTTGATGTGAAAGATGTTATAATAATTTCTAGAAGACAATTTGGTGTATCACAACATG
CATGTCTTATTTTTTTTTAGTTTTAAGTCCTATAGGACTATGAGTCTCTAAGTTATTTGTTTCAGAAAATTATTCTTTTTTTATGTGATA
AATCATATGATTTAAGTGCATGAATAAGCATTTTCCCACACAATGAACATTTGAACTGTGTTTATGAAAATTTTCTGGTTTGCACCATGA
ATTTGTCAAATGGATATTTATAGGAATATATTCACTACTTTGTATACTTTGCAAATTTGTCTCTCTGGCTTTACCCAAGTTCTGAATGCA
TTGTAATTAAAATTTAAGTTTTTCTTTTCCCCCATTAGTAAACATTTAGTGCTACATATGATAACTGCCCAATATTTATTCTATTTACTT
AGCTAAATATTTGCATTCTTGTAACCTTCTATGGTGTTTTGTGGCTCTTATCTTGTGGACCATAAATAACACGGCCCAATAACTCTTTGT
GTTTATGGAGTGTTGTTTTCTTAGAATAATGGAGATGCAGATATAGATACCATAGTCAAGGTACCGCCTTGCTGAAGTATTTATTTATAA
AGAATATTCTGTAGAACCTCTACTACCAGCTATATTTTTAAATCCTGTTTATTTGTAAAGCTAATATGCTCCTCAATGTAATTATTAAAA
ATTCTCAAGTCACAGCTAAACTTACTAATTCTGATTTTAGTGTAGCCCCTAAATTAAAAATGGCTTCCATATGCCACTCTGTACCCCAAA
GAGAGTTCTCATGAAATATTCTCCAGAATGTATTCATTATCAAGAAAATGTCAATCGTCACTTCCTCGTTTTAACTCAGCTGAAACACCA
GGACCCAATAGAGAGGGCAAGCTGAGCATCTGTATTTCCAGATAAAAGTTGTTATTGATGTATAAACTCGTTGCGTGATTAGTGATGTTG
GAAGCATTTTAGCACAAAACAGCCTTGTGTCTTAGATGATATCTGTAACCAGTTTCTGAATCCCGTTGGATAAAACTGTATTGTGATATC

>26737_26737_1_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000295571_SYNPR_chr3_63466508_ENST00000295894_length(amino acids)=547AA_BP=290
MSGSEDSRGLQVAMLMLFVFGVLLHEVSLSGQNEAPPNTHSIPGEPLYNYASIRLPEEHIPFFLHNNRHIATVCRKDSLCPYKKHLEKLK
YCWGYEKSCKPEFRFGYPVCSYVDMGWTDTLESAEDIFWKQADFGYARERLEEMHVLCQPKETSDSSLVCSRYLQYCRATNLYLDLRNIK
RNHDRFKEDFFQSGEIGGHCKLDIRTLTSEGQRKSPLQSWFAELQSYTQLNFRPIEDAKCDIVIEKPTYFMKLDAGVNMYHHFCDFINLY
ITQHVNNSFSTDVYIVMWDTLFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSS
AEFFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAI
HSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGP

--------------------------------------------------------------
>26737_26737_2_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000295571_SYNPR_chr3_63466508_ENST00000478300_length(transcript)=3450nt_BP=1236nt
GCCGTCTCCTCCGCCTCCTCCTCGGTAGTTCACGGCTGCCCCGGCTCCAGGCCTGTGGAAATCGAATCAAGGGTTTCTGGAGTGGAGTGA
TTCCAGCTGCTTTGAGCTGAAGGAAAAGTAGCCTGGCCAGTAAAGCGTCCGTGTGCTGGAGGAGTGCAGCCACCCATCCCGGCGGGCCTT
GCAGGACGACCGACACCAGGAAGGCTTTGTGCCAGGCCCAGCAGCCACCCCCAGCCGCCTTATGCAAGTGGGTACATGCCCTCGCCAGAC
GCCAGCTTTCTGATCTGCGTCTTTAGATTTTTTCCATCGCCTAAGCGTTACTTCTCCACTGATCGGTTTTAGAGACCTGAAACATCACAG
AAGCTTCTGAGTGGTTCTGAAGATTCAAGAGGTTTGCAGGTTGCTATGTTAATGTTGTTTGTCTTTGGAGTCTTACTTCATGAAGTCTCA
CTGAGTGGTCAGAATGAAGCTCCTCCTAATACTCACAGCATTCCAGGCGAACCTCTGTATAACTATGCCAGCATCCGCTTGCCAGAGGAG
CACATTCCCTTCTTTTTGCACAACAATAGGCATATTGCCACTGTCTGTAGGAAAGACTCTCTTTGTCCATATAAGAAACACCTAGAGAAG
CTAAAGTACTGCTGGGGTTATGAGAAATCCTGCAAACCAGAGTTCAGGTTTGGTTACCCAGTTTGCAGCTATGTCGACATGGGATGGACG
GACACTCTTGAGTCAGCTGAGGACATATTTTGGAAACAAGCTGACTTTGGATATGCCAGAGAGAGGCTGGAGGAGATGCATGTGCTCTGT
CAGCCTAAGGAAACGAGTGACTCAAGTCTGGTGTGTTCCCGTTATCTTCAGTACTGCAGAGCAACCAATCTCTATCTTGATTTAAGAAAC
ATCAAGAGAAATCATGACAGATTTAAGGAGGACTTTTTCCAGAGTGGTGAAATTGGAGGGCACTGTAAACTTGACATCCGTACATTGACG
TCTGAAGGTCAGCGCAAAAGCCCTCTGCAGTCATGGTTTGCTGAGCTACAAAGCTATACTCAGCTCAACTTCAGACCTATAGAAGATGCT
AAATGTGACATTGTCATTGAAAAACCAACATATTTCATGAAATTAGATGCAGGTGTTAACATGTATCACCACTTCTGTGATTTCATCAAT
CTTTATATTACTCAGCACGTTAATAACTCATTCAGTACTGACGTGTACATCGTGATGTGGGACACCCTTTTTGCAATCTTTGCATTTGCA
ACATGCGGTGGCTATTCTGGAGGCCTGCGGCTGAGTGTGGACTGCGTCAACAAGACAGAAAGTAACCTCAGCATCGACATAGCGTTTGCC
TACCCATTCAGGTTGCACCAGGTGACGTTTGAGGTGCCCACCTGCGAGGGAAAGGAACGGCAGAAGCTGGCATTGATTGGTGACTCCTCG
TCTTCAGCAGAGTTCTTCGTCACTGTTGCTGTCTTCGCCTTCCTCTACTCTTTGGCTGCCACTGTCGTTTACATTTTCTTCCAGAACAAA
TACCGGGAAAACAACCGGGGCCCACTCATTGACTTCATTGTCACTGTAGTCTTTTCGTTCTTGTGGTTGGTGGGTTCATCAGCTTGGGCA
AAAGGACTGTCTGACGTCAAAGTTGCAACGGATCCCAAGGAAGTATTGCTACTAATGTCAGCTTGCAAACAGCCATCCAACAAATGCATG
GCTATCCACAGCCCTGTTATGTCAAGCTTAAACACTTCTGTGGTCTTTGGATTCTTGAACTTTATTCTCTGGGCTGGAAACATATGGTTT
GTTTTCAAGGAGACCGGCTGGCATTCTTCGGGACAGAGATATCTTTCAGATCCAATGGAGAAGCACTCCAGCAGCTATAATCAAGGTGGT
TACAACCAAGACAGCTATGGATCAAGCAGTGGGTACAGTCAGCAGGCGAGTTTGGGGCCAACCTCAGATGAGTTTGGCCAACAGCCTACT
GGCCCCACTTCCTTTACCAATCAGATTTAACAGAGTAGCATTTGCATTCTTCTGCAGTCGCCTCACCATCTTCCATTTCAGTGGCAGAAG
AATTTTTTAAGGGTTTCAATCAATTATTAATGCAGAGAGTATTGAATGTAAATCAGAGCTCTCTAGTCTTCATTAAGGCAGCAAGTCCTG
GGTTGTGAAAAATGATACTTAGAGATGAGGCGACATGAGGAGATATATTATTCATCATAGATGGCTAATTGGAGAGTACCTTGTTATATA
TACAGATACTTTCATGGTCATTTTGTATGTATGTTAAAGTAGTAGAAGTATTTTGTAGCTTAAAGTCTCTAGTATGTAATATGCATAAAG
TAAATCAAATAGCGTTGAGTTTTCTTATGCATTTTGATGTGAAAGATGTTATAATAATTTCTAGAAGACAATTTGGTGTATCACAACATG
CATGTCTTATTTTTTTTTAGTTTTAAGTCCTATAGGACTATGAGTCTCTAAGTTATTTGTTTCAGAAAATTATTCTTTTTTTATGTGATA
AATCATATGATTTAAGTGCATGAATAAGCATTTTCCCACACAATGAACATTTGAACTGTGTTTATGAAAATTTTCTGGTTTGCACCATGA
ATTTGTCAAATGGATATTTATAGGAATATATTCACTACTTTGTATACTTTGCAAATTTGTCTCTCTGGCTTTACCCAAGTTCTGAATGCA
TTGTAATTAAAATTTAAGTTTTTCTTTTCCCCCATTAGTAAACATTTAGTGCTACATATGATAACTGCCCAATATTTATTCTATTTACTT
AGCTAAATATTTGCATTCTTGTAACCTTCTATGGTGTTTTGTGGCTCTTATCTTGTGGACCATAAATAACACGGCCCAATAACTCTTTGT
GTTTATGGAGTGTTGTTTTCTTAGAATAATGGAGATGCAGATATAGATACCATAGTCAAGGTACCGCCTTGCTGAAGTATTTATTTATAA
AGAATATTCTGTAGAACCTCTACTACCAGCTATATTTTTAAATCCTGTTTATTTGTAAAGCTAATATGCTCCTCAATGTAATTATTAAAA
ATTCTCAAGTCACAGCTAAACTTACTAATTCTGATTTTAGTGTAGCCCCTAAATTAAAAATGGCTTCCATATGCCACTCTGTACCCCAAA
GAGAGTTCTCATGAAATATTCTCCAGAATGTATTCATTATCAAGAAAATGTCAATCGTCACTTCCTCGTTTTAACTCAGCTGAAACACCA
GGACCCAATAGAGAGGGCAAGCTGAGCATCTGTATTTCCAGATAAAAGTTGTTATTGATGTATAAACTCGTTGCGTGATTAGTGATGTTG
GAAGCATTTTAGCACAAAACAGCCTTGTGTCTTAGATGATATCTGTAACCAGTTTCTGAATCCCGTTGGATAAAACTGTATTGTGATATC

>26737_26737_2_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000295571_SYNPR_chr3_63466508_ENST00000478300_length(amino acids)=547AA_BP=290
MSGSEDSRGLQVAMLMLFVFGVLLHEVSLSGQNEAPPNTHSIPGEPLYNYASIRLPEEHIPFFLHNNRHIATVCRKDSLCPYKKHLEKLK
YCWGYEKSCKPEFRFGYPVCSYVDMGWTDTLESAEDIFWKQADFGYARERLEEMHVLCQPKETSDSSLVCSRYLQYCRATNLYLDLRNIK
RNHDRFKEDFFQSGEIGGHCKLDIRTLTSEGQRKSPLQSWFAELQSYTQLNFRPIEDAKCDIVIEKPTYFMKLDAGVNMYHHFCDFINLY
ITQHVNNSFSTDVYIVMWDTLFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSS
AEFFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAI
HSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGP

--------------------------------------------------------------
>26737_26737_3_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000295571_SYNPR_chr3_63466508_ENST00000479198_length(transcript)=3530nt_BP=1236nt
GCCGTCTCCTCCGCCTCCTCCTCGGTAGTTCACGGCTGCCCCGGCTCCAGGCCTGTGGAAATCGAATCAAGGGTTTCTGGAGTGGAGTGA
TTCCAGCTGCTTTGAGCTGAAGGAAAAGTAGCCTGGCCAGTAAAGCGTCCGTGTGCTGGAGGAGTGCAGCCACCCATCCCGGCGGGCCTT
GCAGGACGACCGACACCAGGAAGGCTTTGTGCCAGGCCCAGCAGCCACCCCCAGCCGCCTTATGCAAGTGGGTACATGCCCTCGCCAGAC
GCCAGCTTTCTGATCTGCGTCTTTAGATTTTTTCCATCGCCTAAGCGTTACTTCTCCACTGATCGGTTTTAGAGACCTGAAACATCACAG
AAGCTTCTGAGTGGTTCTGAAGATTCAAGAGGTTTGCAGGTTGCTATGTTAATGTTGTTTGTCTTTGGAGTCTTACTTCATGAAGTCTCA
CTGAGTGGTCAGAATGAAGCTCCTCCTAATACTCACAGCATTCCAGGCGAACCTCTGTATAACTATGCCAGCATCCGCTTGCCAGAGGAG
CACATTCCCTTCTTTTTGCACAACAATAGGCATATTGCCACTGTCTGTAGGAAAGACTCTCTTTGTCCATATAAGAAACACCTAGAGAAG
CTAAAGTACTGCTGGGGTTATGAGAAATCCTGCAAACCAGAGTTCAGGTTTGGTTACCCAGTTTGCAGCTATGTCGACATGGGATGGACG
GACACTCTTGAGTCAGCTGAGGACATATTTTGGAAACAAGCTGACTTTGGATATGCCAGAGAGAGGCTGGAGGAGATGCATGTGCTCTGT
CAGCCTAAGGAAACGAGTGACTCAAGTCTGGTGTGTTCCCGTTATCTTCAGTACTGCAGAGCAACCAATCTCTATCTTGATTTAAGAAAC
ATCAAGAGAAATCATGACAGATTTAAGGAGGACTTTTTCCAGAGTGGTGAAATTGGAGGGCACTGTAAACTTGACATCCGTACATTGACG
TCTGAAGGTCAGCGCAAAAGCCCTCTGCAGTCATGGTTTGCTGAGCTACAAAGCTATACTCAGCTCAACTTCAGACCTATAGAAGATGCT
AAATGTGACATTGTCATTGAAAAACCAACATATTTCATGAAATTAGATGCAGGTGTTAACATGTATCACCACTTCTGTGATTTCATCAAT
CTTTATATTACTCAGCACGTTAATAACTCATTCAGTACTGACGTGTACATCGTGATGTGGGACACCCTTTTTGCAATCTTTGCATTTGCA
ACATGCGGTGGCTATTCTGGAGGCCTGCGGCTGAGTGTGGACTGCGTCAACAAGACAGAAAGTAACCTCAGCATCGACATAGCGTTTGCC
TACCCATTCAGGTTGCACCAGGTGACGTTTGAGGTGCCCACCTGCGAGGGAAAGGAACGGCAGAAGCTGGCATTGATTGGTGACTCCTCG
TCTTCAGCAGAGTTCTTCGTCACTGTTGCTGTCTTCGCCTTCCTCTACTCTTTGGCTGCCACTGTCGTTTACATTTTCTTCCAGAACAAA
TACCGGGAAAACAACCGGGGCCCACTCATTGACTTCATTGTCACTGTAGTCTTTTCGTTCTTGTGGTTGGTGGGTTCATCAGCTTGGGCA
AAAGGACTGTCTGACGTCAAAGTTGCAACGGATCCCAAGGAAGTATTGCTACTAATGTCAGCTTGCAAACAGCCATCCAACAAATGCATG
GCTATCCACAGCCCTGTTATGTCAAGCTTAAACACTTCTGTGCTTTCTGAAATTCAATCTGCGAAGGCACTTAAGAAGAGAGAAAGGGTT
GCTACTCTGACTGGACTGTGATTTCTGCTTTGGTCTTTGGATTCTTGAACTTTATTCTCTGGGCTGGAAACATATGGTTTGTTTTCAAGG
AGACCGGCTGGCATTCTTCGGGACAGAGATATCTTTCAGATCCAATGGAGAAGCACTCCAGCAGCTATAATCAAGGTGGTTACAACCAAG
ACAGCTATGGATCAAGCAGTGGGTACAGTCAGCAGGCGAGTTTGGGGCCAACCTCAGATGAGTTTGGCCAACAGCCTACTGGCCCCACTT
CCTTTACCAATCAGATTTAACAGAGTAGCATTTGCATTCTTCTGCAGTCGCCTCACCATCTTCCATTTCAGTGGCAGAAGAATTTTTTAA
GGGTTTCAATCAATTATTAATGCAGAGAGTATTGAATGTAAATCAGAGCTCTCTAGTCTTCATTAAGGCAGCAAGTCCTGGGTTGTGAAA
AATGATACTTAGAGATGAGGCGACATGAGGAGATATATTATTCATCATAGATGGCTAATTGGAGAGTACCTTGTTATATATACAGATACT
TTCATGGTCATTTTGTATGTATGTTAAAGTAGTAGAAGTATTTTGTAGCTTAAAGTCTCTAGTATGTAATATGCATAAAGTAAATCAAAT
AGCGTTGAGTTTTCTTATGCATTTTGATGTGAAAGATGTTATAATAATTTCTAGAAGACAATTTGGTGTATCACAACATGCATGTCTTAT
TTTTTTTTAGTTTTAAGTCCTATAGGACTATGAGTCTCTAAGTTATTTGTTTCAGAAAATTATTCTTTTTTTATGTGATAAATCATATGA
TTTAAGTGCATGAATAAGCATTTTCCCACACAATGAACATTTGAACTGTGTTTATGAAAATTTTCTGGTTTGCACCATGAATTTGTCAAA
TGGATATTTATAGGAATATATTCACTACTTTGTATACTTTGCAAATTTGTCTCTCTGGCTTTACCCAAGTTCTGAATGCATTGTAATTAA
AATTTAAGTTTTTCTTTTCCCCCATTAGTAAACATTTAGTGCTACATATGATAACTGCCCAATATTTATTCTATTTACTTAGCTAAATAT
TTGCATTCTTGTAACCTTCTATGGTGTTTTGTGGCTCTTATCTTGTGGACCATAAATAACACGGCCCAATAACTCTTTGTGTTTATGGAG
TGTTGTTTTCTTAGAATAATGGAGATGCAGATATAGATACCATAGTCAAGGTACCGCCTTGCTGAAGTATTTATTTATAAAGAATATTCT
GTAGAACCTCTACTACCAGCTATATTTTTAAATCCTGTTTATTTGTAAAGCTAATATGCTCCTCAATGTAATTATTAAAAATTCTCAAGT
CACAGCTAAACTTACTAATTCTGATTTTAGTGTAGCCCCTAAATTAAAAATGGCTTCCATATGCCACTCTGTACCCCAAAGAGAGTTCTC
ATGAAATATTCTCCAGAATGTATTCATTATCAAGAAAATGTCAATCGTCACTTCCTCGTTTTAACTCAGCTGAAACACCAGGACCCAATA
GAGAGGGCAAGCTGAGCATCTGTATTTCCAGATAAAAGTTGTTATTGATGTATAAACTCGTTGCGTGATTAGTGATGTTGGAAGCATTTT
AGCACAAAACAGCCTTGTGTCTTAGATGATATCTGTAACCAGTTTCTGAATCCCGTTGGATAAAACTGTATTGTGATATCTATTTGATGT

>26737_26737_3_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000295571_SYNPR_chr3_63466508_ENST00000479198_length(amino acids)=484AA_BP=290
MSGSEDSRGLQVAMLMLFVFGVLLHEVSLSGQNEAPPNTHSIPGEPLYNYASIRLPEEHIPFFLHNNRHIATVCRKDSLCPYKKHLEKLK
YCWGYEKSCKPEFRFGYPVCSYVDMGWTDTLESAEDIFWKQADFGYARERLEEMHVLCQPKETSDSSLVCSRYLQYCRATNLYLDLRNIK
RNHDRFKEDFFQSGEIGGHCKLDIRTLTSEGQRKSPLQSWFAELQSYTQLNFRPIEDAKCDIVIEKPTYFMKLDAGVNMYHHFCDFINLY
ITQHVNNSFSTDVYIVMWDTLFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSS
AEFFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAI

--------------------------------------------------------------
>26737_26737_4_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000383701_SYNPR_chr3_63466508_ENST00000295894_length(transcript)=3788nt_BP=1574nt
CTTTCCGGCCCTGGTGAGGGAGCTGGCGGACTCGCGCGAACGTTCGCGGGAGAACGCCAGGAAGGGCAGATGGTTCCTCGACTCTGAGCC
CCTCCCTGCTGCGCTCGCCGGGTCGAGGCCGCTCGCCGGGCTGAAGCCGCTCCGAGCGTCGGGCCCCGCGCCCTGGCCCTCCTGGGTGTA
GTCCCGGTCCTGCCTCTGCGGGGCCCGAGCCCGCCCACGGCGCCGGCTGGCCAAGGTGTCCCAGCTGCTCCTTGGCGCCCCCTGGCCCAG
CTCCCGCGCCCGAGGTTTCCGGTGAGCGGCAGTAGCCGGTTATGACGACTCCCTCCTCTGGAACAGCCGCCGTCTCCTCCGCCTCCTCCT
CGGTAGTTCACGGCTGCCCCGGCTCCAGGCCTGTGGAAATCGAATCAAGGGTTTCTGGAGTGGAGTGATTCCAGCTGCTTTGAGCTGAAG
GAAAAGTAGCCTGGCCAGTAAAGCGTCCGTGTGCTGGAGGAGTGCAGCCACCCATCCCGGCGGGCCTTGCAGGACGACCGACACCAGGAA
GGCTTTGTGCCAGGCCCAGCAGCCACCCCCAGCCGCCTTATGCAAGTGGGTACATGCCCTCGCCAGACGCCAGCTTTCTGATCTGCGTCT
TTAGATTTTTTCCATCGCCTAAGCGTTACTTCTCCACTGATCGGTTTTAGAGACCTGAAACATCACAGAAGCTTCTGAGTGGTTCTGAAG
ATTCAAGAGGTTTGCAGGTTGCTATGTTAATGTTGTTTGTCTTTGGAGTCTTACTTCATGAAGTCTCACTGAGTGGTCAGAATGAAGCTC
CTCCTAATACTCACAGCATTCCAGGCGAACCTCTGTATAACTATGCCAGCATCCGCTTGCCAGAGGAGCACATTCCCTTCTTTTTGCACA
ACAATAGGCATATTGCCACTGTCTGTAGGAAAGACTCTCTTTGTCCATATAAGAAACACCTAGAGAAGCTAAAGTACTGCTGGGGTTATG
AGAAATCCTGCAAACCAGAGTTCAGGTTTGGTTACCCAGTTTGCAGCTATGTCGACATGGGATGGACGGACACTCTTGAGTCAGCTGAGG
ACATATTTTGGAAACAAGCTGACTTTGGATATGCCAGAGAGAGGCTGGAGGAGATGCATGTGCTCTGTCAGCCTAAGGAAACGAGTGACT
CAAGTCTGGTGTGTTCCCGTTATCTTCAGTACTGCAGAGCAACCAATCTCTATCTTGATTTAAGAAACATCAAGAGAAATCATGACAGAT
TTAAGGAGGACTTTTTCCAGAGTGGTGAAATTGGAGGGCACTGTAAACTTGACATCCGTACATTGACGTCTGAAGGTCAGCGCAAAAGCC
CTCTGCAGTCATGGTTTGCTGAGCTACAAAGCTATACTCAGCTCAACTTCAGACCTATAGAAGATGCTAAATGTGACATTGTCATTGAAA
AACCAACATATTTCATGAAATTAGATGCAGGTGTTAACATGTATCACCACTTCTGTGATTTCATCAATCTTTATATTACTCAGCACGTTA
ATAACTCATTCAGTACTGACGTGTACATCGTGATGTGGGACACCCTTTTTGCAATCTTTGCATTTGCAACATGCGGTGGCTATTCTGGAG
GCCTGCGGCTGAGTGTGGACTGCGTCAACAAGACAGAAAGTAACCTCAGCATCGACATAGCGTTTGCCTACCCATTCAGGTTGCACCAGG
TGACGTTTGAGGTGCCCACCTGCGAGGGAAAGGAACGGCAGAAGCTGGCATTGATTGGTGACTCCTCGTCTTCAGCAGAGTTCTTCGTCA
CTGTTGCTGTCTTCGCCTTCCTCTACTCTTTGGCTGCCACTGTCGTTTACATTTTCTTCCAGAACAAATACCGGGAAAACAACCGGGGCC
CACTCATTGACTTCATTGTCACTGTAGTCTTTTCGTTCTTGTGGTTGGTGGGTTCATCAGCTTGGGCAAAAGGACTGTCTGACGTCAAAG
TTGCAACGGATCCCAAGGAAGTATTGCTACTAATGTCAGCTTGCAAACAGCCATCCAACAAATGCATGGCTATCCACAGCCCTGTTATGT
CAAGCTTAAACACTTCTGTGGTCTTTGGATTCTTGAACTTTATTCTCTGGGCTGGAAACATATGGTTTGTTTTCAAGGAGACCGGCTGGC
ATTCTTCGGGACAGAGATATCTTTCAGATCCAATGGAGAAGCACTCCAGCAGCTATAATCAAGGTGGTTACAACCAAGACAGCTATGGAT
CAAGCAGTGGGTACAGTCAGCAGGCGAGTTTGGGGCCAACCTCAGATGAGTTTGGCCAACAGCCTACTGGCCCCACTTCCTTTACCAATC
AGATTTAACAGAGTAGCATTTGCATTCTTCTGCAGTCGCCTCACCATCTTCCATTTCAGTGGCAGAAGAATTTTTTAAGGGTTTCAATCA
ATTATTAATGCAGAGAGTATTGAATGTAAATCAGAGCTCTCTAGTCTTCATTAAGGCAGCAAGTCCTGGGTTGTGAAAAATGATACTTAG
AGATGAGGCGACATGAGGAGATATATTATTCATCATAGATGGCTAATTGGAGAGTACCTTGTTATATATACAGATACTTTCATGGTCATT
TTGTATGTATGTTAAAGTAGTAGAAGTATTTTGTAGCTTAAAGTCTCTAGTATGTAATATGCATAAAGTAAATCAAATAGCGTTGAGTTT
TCTTATGCATTTTGATGTGAAAGATGTTATAATAATTTCTAGAAGACAATTTGGTGTATCACAACATGCATGTCTTATTTTTTTTTAGTT
TTAAGTCCTATAGGACTATGAGTCTCTAAGTTATTTGTTTCAGAAAATTATTCTTTTTTTATGTGATAAATCATATGATTTAAGTGCATG
AATAAGCATTTTCCCACACAATGAACATTTGAACTGTGTTTATGAAAATTTTCTGGTTTGCACCATGAATTTGTCAAATGGATATTTATA
GGAATATATTCACTACTTTGTATACTTTGCAAATTTGTCTCTCTGGCTTTACCCAAGTTCTGAATGCATTGTAATTAAAATTTAAGTTTT
TCTTTTCCCCCATTAGTAAACATTTAGTGCTACATATGATAACTGCCCAATATTTATTCTATTTACTTAGCTAAATATTTGCATTCTTGT
AACCTTCTATGGTGTTTTGTGGCTCTTATCTTGTGGACCATAAATAACACGGCCCAATAACTCTTTGTGTTTATGGAGTGTTGTTTTCTT
AGAATAATGGAGATGCAGATATAGATACCATAGTCAAGGTACCGCCTTGCTGAAGTATTTATTTATAAAGAATATTCTGTAGAACCTCTA
CTACCAGCTATATTTTTAAATCCTGTTTATTTGTAAAGCTAATATGCTCCTCAATGTAATTATTAAAAATTCTCAAGTCACAGCTAAACT
TACTAATTCTGATTTTAGTGTAGCCCCTAAATTAAAAATGGCTTCCATATGCCACTCTGTACCCCAAAGAGAGTTCTCATGAAATATTCT
CCAGAATGTATTCATTATCAAGAAAATGTCAATCGTCACTTCCTCGTTTTAACTCAGCTGAAACACCAGGACCCAATAGAGAGGGCAAGC
TGAGCATCTGTATTTCCAGATAAAAGTTGTTATTGATGTATAAACTCGTTGCGTGATTAGTGATGTTGGAAGCATTTTAGCACAAAACAG
CCTTGTGTCTTAGATGATATCTGTAACCAGTTTCTGAATCCCGTTGGATAAAACTGTATTGTGATATCTATTTGATGTTAATAAAGTTAT

>26737_26737_4_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000383701_SYNPR_chr3_63466508_ENST00000295894_length(amino acids)=547AA_BP=290
MSGSEDSRGLQVAMLMLFVFGVLLHEVSLSGQNEAPPNTHSIPGEPLYNYASIRLPEEHIPFFLHNNRHIATVCRKDSLCPYKKHLEKLK
YCWGYEKSCKPEFRFGYPVCSYVDMGWTDTLESAEDIFWKQADFGYARERLEEMHVLCQPKETSDSSLVCSRYLQYCRATNLYLDLRNIK
RNHDRFKEDFFQSGEIGGHCKLDIRTLTSEGQRKSPLQSWFAELQSYTQLNFRPIEDAKCDIVIEKPTYFMKLDAGVNMYHHFCDFINLY
ITQHVNNSFSTDVYIVMWDTLFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSS
AEFFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAI
HSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGP

--------------------------------------------------------------
>26737_26737_5_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000383701_SYNPR_chr3_63466508_ENST00000478300_length(transcript)=3788nt_BP=1574nt
CTTTCCGGCCCTGGTGAGGGAGCTGGCGGACTCGCGCGAACGTTCGCGGGAGAACGCCAGGAAGGGCAGATGGTTCCTCGACTCTGAGCC
CCTCCCTGCTGCGCTCGCCGGGTCGAGGCCGCTCGCCGGGCTGAAGCCGCTCCGAGCGTCGGGCCCCGCGCCCTGGCCCTCCTGGGTGTA
GTCCCGGTCCTGCCTCTGCGGGGCCCGAGCCCGCCCACGGCGCCGGCTGGCCAAGGTGTCCCAGCTGCTCCTTGGCGCCCCCTGGCCCAG
CTCCCGCGCCCGAGGTTTCCGGTGAGCGGCAGTAGCCGGTTATGACGACTCCCTCCTCTGGAACAGCCGCCGTCTCCTCCGCCTCCTCCT
CGGTAGTTCACGGCTGCCCCGGCTCCAGGCCTGTGGAAATCGAATCAAGGGTTTCTGGAGTGGAGTGATTCCAGCTGCTTTGAGCTGAAG
GAAAAGTAGCCTGGCCAGTAAAGCGTCCGTGTGCTGGAGGAGTGCAGCCACCCATCCCGGCGGGCCTTGCAGGACGACCGACACCAGGAA
GGCTTTGTGCCAGGCCCAGCAGCCACCCCCAGCCGCCTTATGCAAGTGGGTACATGCCCTCGCCAGACGCCAGCTTTCTGATCTGCGTCT
TTAGATTTTTTCCATCGCCTAAGCGTTACTTCTCCACTGATCGGTTTTAGAGACCTGAAACATCACAGAAGCTTCTGAGTGGTTCTGAAG
ATTCAAGAGGTTTGCAGGTTGCTATGTTAATGTTGTTTGTCTTTGGAGTCTTACTTCATGAAGTCTCACTGAGTGGTCAGAATGAAGCTC
CTCCTAATACTCACAGCATTCCAGGCGAACCTCTGTATAACTATGCCAGCATCCGCTTGCCAGAGGAGCACATTCCCTTCTTTTTGCACA
ACAATAGGCATATTGCCACTGTCTGTAGGAAAGACTCTCTTTGTCCATATAAGAAACACCTAGAGAAGCTAAAGTACTGCTGGGGTTATG
AGAAATCCTGCAAACCAGAGTTCAGGTTTGGTTACCCAGTTTGCAGCTATGTCGACATGGGATGGACGGACACTCTTGAGTCAGCTGAGG
ACATATTTTGGAAACAAGCTGACTTTGGATATGCCAGAGAGAGGCTGGAGGAGATGCATGTGCTCTGTCAGCCTAAGGAAACGAGTGACT
CAAGTCTGGTGTGTTCCCGTTATCTTCAGTACTGCAGAGCAACCAATCTCTATCTTGATTTAAGAAACATCAAGAGAAATCATGACAGAT
TTAAGGAGGACTTTTTCCAGAGTGGTGAAATTGGAGGGCACTGTAAACTTGACATCCGTACATTGACGTCTGAAGGTCAGCGCAAAAGCC
CTCTGCAGTCATGGTTTGCTGAGCTACAAAGCTATACTCAGCTCAACTTCAGACCTATAGAAGATGCTAAATGTGACATTGTCATTGAAA
AACCAACATATTTCATGAAATTAGATGCAGGTGTTAACATGTATCACCACTTCTGTGATTTCATCAATCTTTATATTACTCAGCACGTTA
ATAACTCATTCAGTACTGACGTGTACATCGTGATGTGGGACACCCTTTTTGCAATCTTTGCATTTGCAACATGCGGTGGCTATTCTGGAG
GCCTGCGGCTGAGTGTGGACTGCGTCAACAAGACAGAAAGTAACCTCAGCATCGACATAGCGTTTGCCTACCCATTCAGGTTGCACCAGG
TGACGTTTGAGGTGCCCACCTGCGAGGGAAAGGAACGGCAGAAGCTGGCATTGATTGGTGACTCCTCGTCTTCAGCAGAGTTCTTCGTCA
CTGTTGCTGTCTTCGCCTTCCTCTACTCTTTGGCTGCCACTGTCGTTTACATTTTCTTCCAGAACAAATACCGGGAAAACAACCGGGGCC
CACTCATTGACTTCATTGTCACTGTAGTCTTTTCGTTCTTGTGGTTGGTGGGTTCATCAGCTTGGGCAAAAGGACTGTCTGACGTCAAAG
TTGCAACGGATCCCAAGGAAGTATTGCTACTAATGTCAGCTTGCAAACAGCCATCCAACAAATGCATGGCTATCCACAGCCCTGTTATGT
CAAGCTTAAACACTTCTGTGGTCTTTGGATTCTTGAACTTTATTCTCTGGGCTGGAAACATATGGTTTGTTTTCAAGGAGACCGGCTGGC
ATTCTTCGGGACAGAGATATCTTTCAGATCCAATGGAGAAGCACTCCAGCAGCTATAATCAAGGTGGTTACAACCAAGACAGCTATGGAT
CAAGCAGTGGGTACAGTCAGCAGGCGAGTTTGGGGCCAACCTCAGATGAGTTTGGCCAACAGCCTACTGGCCCCACTTCCTTTACCAATC
AGATTTAACAGAGTAGCATTTGCATTCTTCTGCAGTCGCCTCACCATCTTCCATTTCAGTGGCAGAAGAATTTTTTAAGGGTTTCAATCA
ATTATTAATGCAGAGAGTATTGAATGTAAATCAGAGCTCTCTAGTCTTCATTAAGGCAGCAAGTCCTGGGTTGTGAAAAATGATACTTAG
AGATGAGGCGACATGAGGAGATATATTATTCATCATAGATGGCTAATTGGAGAGTACCTTGTTATATATACAGATACTTTCATGGTCATT
TTGTATGTATGTTAAAGTAGTAGAAGTATTTTGTAGCTTAAAGTCTCTAGTATGTAATATGCATAAAGTAAATCAAATAGCGTTGAGTTT
TCTTATGCATTTTGATGTGAAAGATGTTATAATAATTTCTAGAAGACAATTTGGTGTATCACAACATGCATGTCTTATTTTTTTTTAGTT
TTAAGTCCTATAGGACTATGAGTCTCTAAGTTATTTGTTTCAGAAAATTATTCTTTTTTTATGTGATAAATCATATGATTTAAGTGCATG
AATAAGCATTTTCCCACACAATGAACATTTGAACTGTGTTTATGAAAATTTTCTGGTTTGCACCATGAATTTGTCAAATGGATATTTATA
GGAATATATTCACTACTTTGTATACTTTGCAAATTTGTCTCTCTGGCTTTACCCAAGTTCTGAATGCATTGTAATTAAAATTTAAGTTTT
TCTTTTCCCCCATTAGTAAACATTTAGTGCTACATATGATAACTGCCCAATATTTATTCTATTTACTTAGCTAAATATTTGCATTCTTGT
AACCTTCTATGGTGTTTTGTGGCTCTTATCTTGTGGACCATAAATAACACGGCCCAATAACTCTTTGTGTTTATGGAGTGTTGTTTTCTT
AGAATAATGGAGATGCAGATATAGATACCATAGTCAAGGTACCGCCTTGCTGAAGTATTTATTTATAAAGAATATTCTGTAGAACCTCTA
CTACCAGCTATATTTTTAAATCCTGTTTATTTGTAAAGCTAATATGCTCCTCAATGTAATTATTAAAAATTCTCAAGTCACAGCTAAACT
TACTAATTCTGATTTTAGTGTAGCCCCTAAATTAAAAATGGCTTCCATATGCCACTCTGTACCCCAAAGAGAGTTCTCATGAAATATTCT
CCAGAATGTATTCATTATCAAGAAAATGTCAATCGTCACTTCCTCGTTTTAACTCAGCTGAAACACCAGGACCCAATAGAGAGGGCAAGC
TGAGCATCTGTATTTCCAGATAAAAGTTGTTATTGATGTATAAACTCGTTGCGTGATTAGTGATGTTGGAAGCATTTTAGCACAAAACAG
CCTTGTGTCTTAGATGATATCTGTAACCAGTTTCTGAATCCCGTTGGATAAAACTGTATTGTGATATCTATTTGATGTTAATAAAGTTAT

>26737_26737_5_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000383701_SYNPR_chr3_63466508_ENST00000478300_length(amino acids)=547AA_BP=290
MSGSEDSRGLQVAMLMLFVFGVLLHEVSLSGQNEAPPNTHSIPGEPLYNYASIRLPEEHIPFFLHNNRHIATVCRKDSLCPYKKHLEKLK
YCWGYEKSCKPEFRFGYPVCSYVDMGWTDTLESAEDIFWKQADFGYARERLEEMHVLCQPKETSDSSLVCSRYLQYCRATNLYLDLRNIK
RNHDRFKEDFFQSGEIGGHCKLDIRTLTSEGQRKSPLQSWFAELQSYTQLNFRPIEDAKCDIVIEKPTYFMKLDAGVNMYHHFCDFINLY
ITQHVNNSFSTDVYIVMWDTLFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSS
AEFFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAI
HSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGP

--------------------------------------------------------------
>26737_26737_6_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000383701_SYNPR_chr3_63466508_ENST00000479198_length(transcript)=3868nt_BP=1574nt
CTTTCCGGCCCTGGTGAGGGAGCTGGCGGACTCGCGCGAACGTTCGCGGGAGAACGCCAGGAAGGGCAGATGGTTCCTCGACTCTGAGCC
CCTCCCTGCTGCGCTCGCCGGGTCGAGGCCGCTCGCCGGGCTGAAGCCGCTCCGAGCGTCGGGCCCCGCGCCCTGGCCCTCCTGGGTGTA
GTCCCGGTCCTGCCTCTGCGGGGCCCGAGCCCGCCCACGGCGCCGGCTGGCCAAGGTGTCCCAGCTGCTCCTTGGCGCCCCCTGGCCCAG
CTCCCGCGCCCGAGGTTTCCGGTGAGCGGCAGTAGCCGGTTATGACGACTCCCTCCTCTGGAACAGCCGCCGTCTCCTCCGCCTCCTCCT
CGGTAGTTCACGGCTGCCCCGGCTCCAGGCCTGTGGAAATCGAATCAAGGGTTTCTGGAGTGGAGTGATTCCAGCTGCTTTGAGCTGAAG
GAAAAGTAGCCTGGCCAGTAAAGCGTCCGTGTGCTGGAGGAGTGCAGCCACCCATCCCGGCGGGCCTTGCAGGACGACCGACACCAGGAA
GGCTTTGTGCCAGGCCCAGCAGCCACCCCCAGCCGCCTTATGCAAGTGGGTACATGCCCTCGCCAGACGCCAGCTTTCTGATCTGCGTCT
TTAGATTTTTTCCATCGCCTAAGCGTTACTTCTCCACTGATCGGTTTTAGAGACCTGAAACATCACAGAAGCTTCTGAGTGGTTCTGAAG
ATTCAAGAGGTTTGCAGGTTGCTATGTTAATGTTGTTTGTCTTTGGAGTCTTACTTCATGAAGTCTCACTGAGTGGTCAGAATGAAGCTC
CTCCTAATACTCACAGCATTCCAGGCGAACCTCTGTATAACTATGCCAGCATCCGCTTGCCAGAGGAGCACATTCCCTTCTTTTTGCACA
ACAATAGGCATATTGCCACTGTCTGTAGGAAAGACTCTCTTTGTCCATATAAGAAACACCTAGAGAAGCTAAAGTACTGCTGGGGTTATG
AGAAATCCTGCAAACCAGAGTTCAGGTTTGGTTACCCAGTTTGCAGCTATGTCGACATGGGATGGACGGACACTCTTGAGTCAGCTGAGG
ACATATTTTGGAAACAAGCTGACTTTGGATATGCCAGAGAGAGGCTGGAGGAGATGCATGTGCTCTGTCAGCCTAAGGAAACGAGTGACT
CAAGTCTGGTGTGTTCCCGTTATCTTCAGTACTGCAGAGCAACCAATCTCTATCTTGATTTAAGAAACATCAAGAGAAATCATGACAGAT
TTAAGGAGGACTTTTTCCAGAGTGGTGAAATTGGAGGGCACTGTAAACTTGACATCCGTACATTGACGTCTGAAGGTCAGCGCAAAAGCC
CTCTGCAGTCATGGTTTGCTGAGCTACAAAGCTATACTCAGCTCAACTTCAGACCTATAGAAGATGCTAAATGTGACATTGTCATTGAAA
AACCAACATATTTCATGAAATTAGATGCAGGTGTTAACATGTATCACCACTTCTGTGATTTCATCAATCTTTATATTACTCAGCACGTTA
ATAACTCATTCAGTACTGACGTGTACATCGTGATGTGGGACACCCTTTTTGCAATCTTTGCATTTGCAACATGCGGTGGCTATTCTGGAG
GCCTGCGGCTGAGTGTGGACTGCGTCAACAAGACAGAAAGTAACCTCAGCATCGACATAGCGTTTGCCTACCCATTCAGGTTGCACCAGG
TGACGTTTGAGGTGCCCACCTGCGAGGGAAAGGAACGGCAGAAGCTGGCATTGATTGGTGACTCCTCGTCTTCAGCAGAGTTCTTCGTCA
CTGTTGCTGTCTTCGCCTTCCTCTACTCTTTGGCTGCCACTGTCGTTTACATTTTCTTCCAGAACAAATACCGGGAAAACAACCGGGGCC
CACTCATTGACTTCATTGTCACTGTAGTCTTTTCGTTCTTGTGGTTGGTGGGTTCATCAGCTTGGGCAAAAGGACTGTCTGACGTCAAAG
TTGCAACGGATCCCAAGGAAGTATTGCTACTAATGTCAGCTTGCAAACAGCCATCCAACAAATGCATGGCTATCCACAGCCCTGTTATGT
CAAGCTTAAACACTTCTGTGCTTTCTGAAATTCAATCTGCGAAGGCACTTAAGAAGAGAGAAAGGGTTGCTACTCTGACTGGACTGTGAT
TTCTGCTTTGGTCTTTGGATTCTTGAACTTTATTCTCTGGGCTGGAAACATATGGTTTGTTTTCAAGGAGACCGGCTGGCATTCTTCGGG
ACAGAGATATCTTTCAGATCCAATGGAGAAGCACTCCAGCAGCTATAATCAAGGTGGTTACAACCAAGACAGCTATGGATCAAGCAGTGG
GTACAGTCAGCAGGCGAGTTTGGGGCCAACCTCAGATGAGTTTGGCCAACAGCCTACTGGCCCCACTTCCTTTACCAATCAGATTTAACA
GAGTAGCATTTGCATTCTTCTGCAGTCGCCTCACCATCTTCCATTTCAGTGGCAGAAGAATTTTTTAAGGGTTTCAATCAATTATTAATG
CAGAGAGTATTGAATGTAAATCAGAGCTCTCTAGTCTTCATTAAGGCAGCAAGTCCTGGGTTGTGAAAAATGATACTTAGAGATGAGGCG
ACATGAGGAGATATATTATTCATCATAGATGGCTAATTGGAGAGTACCTTGTTATATATACAGATACTTTCATGGTCATTTTGTATGTAT
GTTAAAGTAGTAGAAGTATTTTGTAGCTTAAAGTCTCTAGTATGTAATATGCATAAAGTAAATCAAATAGCGTTGAGTTTTCTTATGCAT
TTTGATGTGAAAGATGTTATAATAATTTCTAGAAGACAATTTGGTGTATCACAACATGCATGTCTTATTTTTTTTTAGTTTTAAGTCCTA
TAGGACTATGAGTCTCTAAGTTATTTGTTTCAGAAAATTATTCTTTTTTTATGTGATAAATCATATGATTTAAGTGCATGAATAAGCATT
TTCCCACACAATGAACATTTGAACTGTGTTTATGAAAATTTTCTGGTTTGCACCATGAATTTGTCAAATGGATATTTATAGGAATATATT
CACTACTTTGTATACTTTGCAAATTTGTCTCTCTGGCTTTACCCAAGTTCTGAATGCATTGTAATTAAAATTTAAGTTTTTCTTTTCCCC
CATTAGTAAACATTTAGTGCTACATATGATAACTGCCCAATATTTATTCTATTTACTTAGCTAAATATTTGCATTCTTGTAACCTTCTAT
GGTGTTTTGTGGCTCTTATCTTGTGGACCATAAATAACACGGCCCAATAACTCTTTGTGTTTATGGAGTGTTGTTTTCTTAGAATAATGG
AGATGCAGATATAGATACCATAGTCAAGGTACCGCCTTGCTGAAGTATTTATTTATAAAGAATATTCTGTAGAACCTCTACTACCAGCTA
TATTTTTAAATCCTGTTTATTTGTAAAGCTAATATGCTCCTCAATGTAATTATTAAAAATTCTCAAGTCACAGCTAAACTTACTAATTCT
GATTTTAGTGTAGCCCCTAAATTAAAAATGGCTTCCATATGCCACTCTGTACCCCAAAGAGAGTTCTCATGAAATATTCTCCAGAATGTA
TTCATTATCAAGAAAATGTCAATCGTCACTTCCTCGTTTTAACTCAGCTGAAACACCAGGACCCAATAGAGAGGGCAAGCTGAGCATCTG
TATTTCCAGATAAAAGTTGTTATTGATGTATAAACTCGTTGCGTGATTAGTGATGTTGGAAGCATTTTAGCACAAAACAGCCTTGTGTCT

>26737_26737_6_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000383701_SYNPR_chr3_63466508_ENST00000479198_length(amino acids)=484AA_BP=290
MSGSEDSRGLQVAMLMLFVFGVLLHEVSLSGQNEAPPNTHSIPGEPLYNYASIRLPEEHIPFFLHNNRHIATVCRKDSLCPYKKHLEKLK
YCWGYEKSCKPEFRFGYPVCSYVDMGWTDTLESAEDIFWKQADFGYARERLEEMHVLCQPKETSDSSLVCSRYLQYCRATNLYLDLRNIK
RNHDRFKEDFFQSGEIGGHCKLDIRTLTSEGQRKSPLQSWFAELQSYTQLNFRPIEDAKCDIVIEKPTYFMKLDAGVNMYHHFCDFINLY
ITQHVNNSFSTDVYIVMWDTLFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSS
AEFFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAI

--------------------------------------------------------------
>26737_26737_7_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000540764_SYNPR_chr3_63466508_ENST00000295894_length(transcript)=2837nt_BP=623nt
AGAAACACCTAGAGAAGCTAAAGTACTGCTGGGGTTATGAGAAATCCTGCAAACCAGAGTTCAGGTTTGGTTACCCAGTTTGCAGCTATG
TCGACATGGGATGGACGGACACTCTTGAGTCAGCTGAGGACATATTTTGGAAACAAGCTGACTTTGGATATGCCAGAGAGAGGCTGGAGG
AGATGCATGTGCTCTGTCAGCCTAAGGAAACGAGTGACTCAAGTCTGGTGTGTTCCCGTTATCTTCAGTACTGCAGAGCAACCAATCTCT
ATCTTGATTTAAGAAACATCAAGAGAAATCATGACAGATTTAAGGAGGACTTTTTCCAGAGTGGTGAAATTGGAGGGCACTGTAAACTTG
ACATCCGTACATTGACGTCTGAAGGTCAGCGCAAAAGCCCTCTGCAGTCATGGTTTGCTGAGCTACAAAGCTATACTCAGCTCAACTTCA
GACCTATAGAAGATGCTAAATGTGACATTGTCATTGAAAAACCAACATATTTCATGAAATTAGATGCAGGTGTTAACATGTATCACCACT
TCTGTGATTTCATCAATCTTTATATTACTCAGCACGTTAATAACTCATTCAGTACTGACGTGTACATCGTGATGTGGGACACCCTTTTTG
CAATCTTTGCATTTGCAACATGCGGTGGCTATTCTGGAGGCCTGCGGCTGAGTGTGGACTGCGTCAACAAGACAGAAAGTAACCTCAGCA
TCGACATAGCGTTTGCCTACCCATTCAGGTTGCACCAGGTGACGTTTGAGGTGCCCACCTGCGAGGGAAAGGAACGGCAGAAGCTGGCAT
TGATTGGTGACTCCTCGTCTTCAGCAGAGTTCTTCGTCACTGTTGCTGTCTTCGCCTTCCTCTACTCTTTGGCTGCCACTGTCGTTTACA
TTTTCTTCCAGAACAAATACCGGGAAAACAACCGGGGCCCACTCATTGACTTCATTGTCACTGTAGTCTTTTCGTTCTTGTGGTTGGTGG
GTTCATCAGCTTGGGCAAAAGGACTGTCTGACGTCAAAGTTGCAACGGATCCCAAGGAAGTATTGCTACTAATGTCAGCTTGCAAACAGC
CATCCAACAAATGCATGGCTATCCACAGCCCTGTTATGTCAAGCTTAAACACTTCTGTGGTCTTTGGATTCTTGAACTTTATTCTCTGGG
CTGGAAACATATGGTTTGTTTTCAAGGAGACCGGCTGGCATTCTTCGGGACAGAGATATCTTTCAGATCCAATGGAGAAGCACTCCAGCA
GCTATAATCAAGGTGGTTACAACCAAGACAGCTATGGATCAAGCAGTGGGTACAGTCAGCAGGCGAGTTTGGGGCCAACCTCAGATGAGT
TTGGCCAACAGCCTACTGGCCCCACTTCCTTTACCAATCAGATTTAACAGAGTAGCATTTGCATTCTTCTGCAGTCGCCTCACCATCTTC
CATTTCAGTGGCAGAAGAATTTTTTAAGGGTTTCAATCAATTATTAATGCAGAGAGTATTGAATGTAAATCAGAGCTCTCTAGTCTTCAT
TAAGGCAGCAAGTCCTGGGTTGTGAAAAATGATACTTAGAGATGAGGCGACATGAGGAGATATATTATTCATCATAGATGGCTAATTGGA
GAGTACCTTGTTATATATACAGATACTTTCATGGTCATTTTGTATGTATGTTAAAGTAGTAGAAGTATTTTGTAGCTTAAAGTCTCTAGT
ATGTAATATGCATAAAGTAAATCAAATAGCGTTGAGTTTTCTTATGCATTTTGATGTGAAAGATGTTATAATAATTTCTAGAAGACAATT
TGGTGTATCACAACATGCATGTCTTATTTTTTTTTAGTTTTAAGTCCTATAGGACTATGAGTCTCTAAGTTATTTGTTTCAGAAAATTAT
TCTTTTTTTATGTGATAAATCATATGATTTAAGTGCATGAATAAGCATTTTCCCACACAATGAACATTTGAACTGTGTTTATGAAAATTT
TCTGGTTTGCACCATGAATTTGTCAAATGGATATTTATAGGAATATATTCACTACTTTGTATACTTTGCAAATTTGTCTCTCTGGCTTTA
CCCAAGTTCTGAATGCATTGTAATTAAAATTTAAGTTTTTCTTTTCCCCCATTAGTAAACATTTAGTGCTACATATGATAACTGCCCAAT
ATTTATTCTATTTACTTAGCTAAATATTTGCATTCTTGTAACCTTCTATGGTGTTTTGTGGCTCTTATCTTGTGGACCATAAATAACACG
GCCCAATAACTCTTTGTGTTTATGGAGTGTTGTTTTCTTAGAATAATGGAGATGCAGATATAGATACCATAGTCAAGGTACCGCCTTGCT
GAAGTATTTATTTATAAAGAATATTCTGTAGAACCTCTACTACCAGCTATATTTTTAAATCCTGTTTATTTGTAAAGCTAATATGCTCCT
CAATGTAATTATTAAAAATTCTCAAGTCACAGCTAAACTTACTAATTCTGATTTTAGTGTAGCCCCTAAATTAAAAATGGCTTCCATATG
CCACTCTGTACCCCAAAGAGAGTTCTCATGAAATATTCTCCAGAATGTATTCATTATCAAGAAAATGTCAATCGTCACTTCCTCGTTTTA
ACTCAGCTGAAACACCAGGACCCAATAGAGAGGGCAAGCTGAGCATCTGTATTTCCAGATAAAAGTTGTTATTGATGTATAAACTCGTTG
CGTGATTAGTGATGTTGGAAGCATTTTAGCACAAAACAGCCTTGTGTCTTAGATGATATCTGTAACCAGTTTCTGAATCCCGTTGGATAA

>26737_26737_7_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000540764_SYNPR_chr3_63466508_ENST00000295894_length(amino acids)=433AA_BP=176
MGWTDTLESAEDIFWKQADFGYARERLEEMHVLCQPKETSDSSLVCSRYLQYCRATNLYLDLRNIKRNHDRFKEDFFQSGEIGGHCKLDI
RTLTSEGQRKSPLQSWFAELQSYTQLNFRPIEDAKCDIVIEKPTYFMKLDAGVNMYHHFCDFINLYITQHVNNSFSTDVYIVMWDTLFAI
FAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIF
FQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSPVMSSLNTSVVFGFLNFILWAG

--------------------------------------------------------------
>26737_26737_8_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000540764_SYNPR_chr3_63466508_ENST00000478300_length(transcript)=2837nt_BP=623nt
AGAAACACCTAGAGAAGCTAAAGTACTGCTGGGGTTATGAGAAATCCTGCAAACCAGAGTTCAGGTTTGGTTACCCAGTTTGCAGCTATG
TCGACATGGGATGGACGGACACTCTTGAGTCAGCTGAGGACATATTTTGGAAACAAGCTGACTTTGGATATGCCAGAGAGAGGCTGGAGG
AGATGCATGTGCTCTGTCAGCCTAAGGAAACGAGTGACTCAAGTCTGGTGTGTTCCCGTTATCTTCAGTACTGCAGAGCAACCAATCTCT
ATCTTGATTTAAGAAACATCAAGAGAAATCATGACAGATTTAAGGAGGACTTTTTCCAGAGTGGTGAAATTGGAGGGCACTGTAAACTTG
ACATCCGTACATTGACGTCTGAAGGTCAGCGCAAAAGCCCTCTGCAGTCATGGTTTGCTGAGCTACAAAGCTATACTCAGCTCAACTTCA
GACCTATAGAAGATGCTAAATGTGACATTGTCATTGAAAAACCAACATATTTCATGAAATTAGATGCAGGTGTTAACATGTATCACCACT
TCTGTGATTTCATCAATCTTTATATTACTCAGCACGTTAATAACTCATTCAGTACTGACGTGTACATCGTGATGTGGGACACCCTTTTTG
CAATCTTTGCATTTGCAACATGCGGTGGCTATTCTGGAGGCCTGCGGCTGAGTGTGGACTGCGTCAACAAGACAGAAAGTAACCTCAGCA
TCGACATAGCGTTTGCCTACCCATTCAGGTTGCACCAGGTGACGTTTGAGGTGCCCACCTGCGAGGGAAAGGAACGGCAGAAGCTGGCAT
TGATTGGTGACTCCTCGTCTTCAGCAGAGTTCTTCGTCACTGTTGCTGTCTTCGCCTTCCTCTACTCTTTGGCTGCCACTGTCGTTTACA
TTTTCTTCCAGAACAAATACCGGGAAAACAACCGGGGCCCACTCATTGACTTCATTGTCACTGTAGTCTTTTCGTTCTTGTGGTTGGTGG
GTTCATCAGCTTGGGCAAAAGGACTGTCTGACGTCAAAGTTGCAACGGATCCCAAGGAAGTATTGCTACTAATGTCAGCTTGCAAACAGC
CATCCAACAAATGCATGGCTATCCACAGCCCTGTTATGTCAAGCTTAAACACTTCTGTGGTCTTTGGATTCTTGAACTTTATTCTCTGGG
CTGGAAACATATGGTTTGTTTTCAAGGAGACCGGCTGGCATTCTTCGGGACAGAGATATCTTTCAGATCCAATGGAGAAGCACTCCAGCA
GCTATAATCAAGGTGGTTACAACCAAGACAGCTATGGATCAAGCAGTGGGTACAGTCAGCAGGCGAGTTTGGGGCCAACCTCAGATGAGT
TTGGCCAACAGCCTACTGGCCCCACTTCCTTTACCAATCAGATTTAACAGAGTAGCATTTGCATTCTTCTGCAGTCGCCTCACCATCTTC
CATTTCAGTGGCAGAAGAATTTTTTAAGGGTTTCAATCAATTATTAATGCAGAGAGTATTGAATGTAAATCAGAGCTCTCTAGTCTTCAT
TAAGGCAGCAAGTCCTGGGTTGTGAAAAATGATACTTAGAGATGAGGCGACATGAGGAGATATATTATTCATCATAGATGGCTAATTGGA
GAGTACCTTGTTATATATACAGATACTTTCATGGTCATTTTGTATGTATGTTAAAGTAGTAGAAGTATTTTGTAGCTTAAAGTCTCTAGT
ATGTAATATGCATAAAGTAAATCAAATAGCGTTGAGTTTTCTTATGCATTTTGATGTGAAAGATGTTATAATAATTTCTAGAAGACAATT
TGGTGTATCACAACATGCATGTCTTATTTTTTTTTAGTTTTAAGTCCTATAGGACTATGAGTCTCTAAGTTATTTGTTTCAGAAAATTAT
TCTTTTTTTATGTGATAAATCATATGATTTAAGTGCATGAATAAGCATTTTCCCACACAATGAACATTTGAACTGTGTTTATGAAAATTT
TCTGGTTTGCACCATGAATTTGTCAAATGGATATTTATAGGAATATATTCACTACTTTGTATACTTTGCAAATTTGTCTCTCTGGCTTTA
CCCAAGTTCTGAATGCATTGTAATTAAAATTTAAGTTTTTCTTTTCCCCCATTAGTAAACATTTAGTGCTACATATGATAACTGCCCAAT
ATTTATTCTATTTACTTAGCTAAATATTTGCATTCTTGTAACCTTCTATGGTGTTTTGTGGCTCTTATCTTGTGGACCATAAATAACACG
GCCCAATAACTCTTTGTGTTTATGGAGTGTTGTTTTCTTAGAATAATGGAGATGCAGATATAGATACCATAGTCAAGGTACCGCCTTGCT
GAAGTATTTATTTATAAAGAATATTCTGTAGAACCTCTACTACCAGCTATATTTTTAAATCCTGTTTATTTGTAAAGCTAATATGCTCCT
CAATGTAATTATTAAAAATTCTCAAGTCACAGCTAAACTTACTAATTCTGATTTTAGTGTAGCCCCTAAATTAAAAATGGCTTCCATATG
CCACTCTGTACCCCAAAGAGAGTTCTCATGAAATATTCTCCAGAATGTATTCATTATCAAGAAAATGTCAATCGTCACTTCCTCGTTTTA
ACTCAGCTGAAACACCAGGACCCAATAGAGAGGGCAAGCTGAGCATCTGTATTTCCAGATAAAAGTTGTTATTGATGTATAAACTCGTTG
CGTGATTAGTGATGTTGGAAGCATTTTAGCACAAAACAGCCTTGTGTCTTAGATGATATCTGTAACCAGTTTCTGAATCCCGTTGGATAA

>26737_26737_8_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000540764_SYNPR_chr3_63466508_ENST00000478300_length(amino acids)=433AA_BP=176
MGWTDTLESAEDIFWKQADFGYARERLEEMHVLCQPKETSDSSLVCSRYLQYCRATNLYLDLRNIKRNHDRFKEDFFQSGEIGGHCKLDI
RTLTSEGQRKSPLQSWFAELQSYTQLNFRPIEDAKCDIVIEKPTYFMKLDAGVNMYHHFCDFINLYITQHVNNSFSTDVYIVMWDTLFAI
FAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIF
FQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSPVMSSLNTSVVFGFLNFILWAG

--------------------------------------------------------------
>26737_26737_9_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000540764_SYNPR_chr3_63466508_ENST00000479198_length(transcript)=2917nt_BP=623nt
AGAAACACCTAGAGAAGCTAAAGTACTGCTGGGGTTATGAGAAATCCTGCAAACCAGAGTTCAGGTTTGGTTACCCAGTTTGCAGCTATG
TCGACATGGGATGGACGGACACTCTTGAGTCAGCTGAGGACATATTTTGGAAACAAGCTGACTTTGGATATGCCAGAGAGAGGCTGGAGG
AGATGCATGTGCTCTGTCAGCCTAAGGAAACGAGTGACTCAAGTCTGGTGTGTTCCCGTTATCTTCAGTACTGCAGAGCAACCAATCTCT
ATCTTGATTTAAGAAACATCAAGAGAAATCATGACAGATTTAAGGAGGACTTTTTCCAGAGTGGTGAAATTGGAGGGCACTGTAAACTTG
ACATCCGTACATTGACGTCTGAAGGTCAGCGCAAAAGCCCTCTGCAGTCATGGTTTGCTGAGCTACAAAGCTATACTCAGCTCAACTTCA
GACCTATAGAAGATGCTAAATGTGACATTGTCATTGAAAAACCAACATATTTCATGAAATTAGATGCAGGTGTTAACATGTATCACCACT
TCTGTGATTTCATCAATCTTTATATTACTCAGCACGTTAATAACTCATTCAGTACTGACGTGTACATCGTGATGTGGGACACCCTTTTTG
CAATCTTTGCATTTGCAACATGCGGTGGCTATTCTGGAGGCCTGCGGCTGAGTGTGGACTGCGTCAACAAGACAGAAAGTAACCTCAGCA
TCGACATAGCGTTTGCCTACCCATTCAGGTTGCACCAGGTGACGTTTGAGGTGCCCACCTGCGAGGGAAAGGAACGGCAGAAGCTGGCAT
TGATTGGTGACTCCTCGTCTTCAGCAGAGTTCTTCGTCACTGTTGCTGTCTTCGCCTTCCTCTACTCTTTGGCTGCCACTGTCGTTTACA
TTTTCTTCCAGAACAAATACCGGGAAAACAACCGGGGCCCACTCATTGACTTCATTGTCACTGTAGTCTTTTCGTTCTTGTGGTTGGTGG
GTTCATCAGCTTGGGCAAAAGGACTGTCTGACGTCAAAGTTGCAACGGATCCCAAGGAAGTATTGCTACTAATGTCAGCTTGCAAACAGC
CATCCAACAAATGCATGGCTATCCACAGCCCTGTTATGTCAAGCTTAAACACTTCTGTGCTTTCTGAAATTCAATCTGCGAAGGCACTTA
AGAAGAGAGAAAGGGTTGCTACTCTGACTGGACTGTGATTTCTGCTTTGGTCTTTGGATTCTTGAACTTTATTCTCTGGGCTGGAAACAT
ATGGTTTGTTTTCAAGGAGACCGGCTGGCATTCTTCGGGACAGAGATATCTTTCAGATCCAATGGAGAAGCACTCCAGCAGCTATAATCA
AGGTGGTTACAACCAAGACAGCTATGGATCAAGCAGTGGGTACAGTCAGCAGGCGAGTTTGGGGCCAACCTCAGATGAGTTTGGCCAACA
GCCTACTGGCCCCACTTCCTTTACCAATCAGATTTAACAGAGTAGCATTTGCATTCTTCTGCAGTCGCCTCACCATCTTCCATTTCAGTG
GCAGAAGAATTTTTTAAGGGTTTCAATCAATTATTAATGCAGAGAGTATTGAATGTAAATCAGAGCTCTCTAGTCTTCATTAAGGCAGCA
AGTCCTGGGTTGTGAAAAATGATACTTAGAGATGAGGCGACATGAGGAGATATATTATTCATCATAGATGGCTAATTGGAGAGTACCTTG
TTATATATACAGATACTTTCATGGTCATTTTGTATGTATGTTAAAGTAGTAGAAGTATTTTGTAGCTTAAAGTCTCTAGTATGTAATATG
CATAAAGTAAATCAAATAGCGTTGAGTTTTCTTATGCATTTTGATGTGAAAGATGTTATAATAATTTCTAGAAGACAATTTGGTGTATCA
CAACATGCATGTCTTATTTTTTTTTAGTTTTAAGTCCTATAGGACTATGAGTCTCTAAGTTATTTGTTTCAGAAAATTATTCTTTTTTTA
TGTGATAAATCATATGATTTAAGTGCATGAATAAGCATTTTCCCACACAATGAACATTTGAACTGTGTTTATGAAAATTTTCTGGTTTGC
ACCATGAATTTGTCAAATGGATATTTATAGGAATATATTCACTACTTTGTATACTTTGCAAATTTGTCTCTCTGGCTTTACCCAAGTTCT
GAATGCATTGTAATTAAAATTTAAGTTTTTCTTTTCCCCCATTAGTAAACATTTAGTGCTACATATGATAACTGCCCAATATTTATTCTA
TTTACTTAGCTAAATATTTGCATTCTTGTAACCTTCTATGGTGTTTTGTGGCTCTTATCTTGTGGACCATAAATAACACGGCCCAATAAC
TCTTTGTGTTTATGGAGTGTTGTTTTCTTAGAATAATGGAGATGCAGATATAGATACCATAGTCAAGGTACCGCCTTGCTGAAGTATTTA
TTTATAAAGAATATTCTGTAGAACCTCTACTACCAGCTATATTTTTAAATCCTGTTTATTTGTAAAGCTAATATGCTCCTCAATGTAATT
ATTAAAAATTCTCAAGTCACAGCTAAACTTACTAATTCTGATTTTAGTGTAGCCCCTAAATTAAAAATGGCTTCCATATGCCACTCTGTA
CCCCAAAGAGAGTTCTCATGAAATATTCTCCAGAATGTATTCATTATCAAGAAAATGTCAATCGTCACTTCCTCGTTTTAACTCAGCTGA
AACACCAGGACCCAATAGAGAGGGCAAGCTGAGCATCTGTATTTCCAGATAAAAGTTGTTATTGATGTATAAACTCGTTGCGTGATTAGT
GATGTTGGAAGCATTTTAGCACAAAACAGCCTTGTGTCTTAGATGATATCTGTAACCAGTTTCTGAATCCCGTTGGATAAAACTGTATTG

>26737_26737_9_EOGT-SYNPR_EOGT_chr3_69047162_ENST00000540764_SYNPR_chr3_63466508_ENST00000479198_length(amino acids)=370AA_BP=176
MGWTDTLESAEDIFWKQADFGYARERLEEMHVLCQPKETSDSSLVCSRYLQYCRATNLYLDLRNIKRNHDRFKEDFFQSGEIGGHCKLDI
RTLTSEGQRKSPLQSWFAELQSYTQLNFRPIEDAKCDIVIEKPTYFMKLDAGVNMYHHFCDFINLYITQHVNNSFSTDVYIVMWDTLFAI
FAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIF
FQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSPVMSSLNTSVLSEIQSAKALKK

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for EOGT-SYNPR


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for EOGT-SYNPR


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for EOGT-SYNPR


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneEOGTC0265268Adams Oliver syndrome1ORPHANET
HgeneEOGTC3809092ADAMS-OLIVER SYNDROME 41GENOMICS_ENGLAND;UNIPROT
HgeneEOGTC4551482Adams-Oliver syndrome 11CTD_human;GENOMICS_ENGLAND