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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ANK3-TES (FusionGDB2 ID:HG288TG26136)

Fusion Gene Summary for ANK3-TES

check button Fusion gene summary
Fusion gene informationFusion gene name: ANK3-TES
Fusion gene ID: hg288tg26136
HgeneTgene
Gene symbol

ANK3

TES

Gene ID

288

26136

Gene nameankyrin 3testin LIM domain protein
SynonymsANKYRIN-G|MRT37TESS|TESS-2
Cytomap('ANK3')('TES')

10q21.2

7q31.2

Type of geneprotein-codingprotein-coding
Descriptionankyrin-3ankyrin 3, node of Ranvier (ankyrin G)testintestis derived transcript (3 LIM domains)
Modification date2020031320200313
UniProtAcc

Q12955

.
Ensembl transtripts involved in fusion geneENST00000280772, ENST00000373827, 
ENST00000503366, ENST00000355288, 
ENST00000460468, ENST00000510382, 
Fusion gene scores* DoF score28 X 22 X 9=55449 X 6 X 7=378
# samples 2910
** MAII scorelog2(29/5544*10)=-4.25680245212228
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/378*10)=-1.91838623444635
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANK3 [Title/Abstract] AND TES [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANK3(61994445)-TES(115874587), # samples:1
Anticipated loss of major functional domain due to fusion event.ANK3-TES seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ANK3-TES seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ANK3-TES seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ANK3-TES seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ANK3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across TES (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-HU-A4GQANK3chr10

61994445

-TESchr7

115874587

+


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Fusion Gene ORF analysis for ANK3-TES

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000280772ENST00000485009ANK3chr10

61994445

-TESchr7

115874587

+
5CDS-3UTRENST00000373827ENST00000485009ANK3chr10

61994445

-TESchr7

115874587

+
5CDS-3UTRENST00000503366ENST00000485009ANK3chr10

61994445

-TESchr7

115874587

+
5CDS-5UTRENST00000280772ENST00000393481ANK3chr10

61994445

-TESchr7

115874587

+
5CDS-5UTRENST00000280772ENST00000537767ANK3chr10

61994445

-TESchr7

115874587

+
5CDS-5UTRENST00000373827ENST00000393481ANK3chr10

61994445

-TESchr7

115874587

+
5CDS-5UTRENST00000373827ENST00000537767ANK3chr10

61994445

-TESchr7

115874587

+
5CDS-5UTRENST00000503366ENST00000393481ANK3chr10

61994445

-TESchr7

115874587

+
5CDS-5UTRENST00000503366ENST00000537767ANK3chr10

61994445

-TESchr7

115874587

+
In-frameENST00000280772ENST00000358204ANK3chr10

61994445

-TESchr7

115874587

+
In-frameENST00000373827ENST00000358204ANK3chr10

61994445

-TESchr7

115874587

+
In-frameENST00000503366ENST00000358204ANK3chr10

61994445

-TESchr7

115874587

+
intron-3CDSENST00000355288ENST00000358204ANK3chr10

61994445

-TESchr7

115874587

+
intron-3CDSENST00000460468ENST00000358204ANK3chr10

61994445

-TESchr7

115874587

+
intron-3CDSENST00000510382ENST00000358204ANK3chr10

61994445

-TESchr7

115874587

+
intron-3UTRENST00000355288ENST00000485009ANK3chr10

61994445

-TESchr7

115874587

+
intron-3UTRENST00000460468ENST00000485009ANK3chr10

61994445

-TESchr7

115874587

+
intron-3UTRENST00000510382ENST00000485009ANK3chr10

61994445

-TESchr7

115874587

+
intron-5UTRENST00000355288ENST00000393481ANK3chr10

61994445

-TESchr7

115874587

+
intron-5UTRENST00000355288ENST00000537767ANK3chr10

61994445

-TESchr7

115874587

+
intron-5UTRENST00000460468ENST00000393481ANK3chr10

61994445

-TESchr7

115874587

+
intron-5UTRENST00000460468ENST00000537767ANK3chr10

61994445

-TESchr7

115874587

+
intron-5UTRENST00000510382ENST00000393481ANK3chr10

61994445

-TESchr7

115874587

+
intron-5UTRENST00000510382ENST00000537767ANK3chr10

61994445

-TESchr7

115874587

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000280772ANK3chr1061994445-ENST00000358204TESchr7115874587+362910891922327711
ENST00000373827ANK3chr1061994445-ENST00000358204TESchr7115874587+35901050242288754
ENST00000503366ANK3chr1061994445-ENST00000358204TESchr7115874587+35229821362220694

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000280772ENST00000358204ANK3chr1061994445-TESchr7115874587+0.0020909610.99790907
ENST00000373827ENST00000358204ANK3chr1061994445-TESchr7115874587+0.0016373910.9983626
ENST00000503366ENST00000358204ANK3chr1061994445-TESchr7115874587+0.0010785610.9989215

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Fusion Genomic Features for ANK3-TES


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ANK3chr1061994445-TESchr7115874587+1.37E-070.9999999
ANK3chr1061994445-TESchr7115874587+1.37E-070.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ANK3-TES


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:61994445/chr7:115874587)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ANK3

Q12955

.
FUNCTION: In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments. Regulates KCNA1 channel activity in function of dietary Mg(2+) levels, and thereby contributes to the regulation of renal Mg(2+) reabsorption (PubMed:23903368). {ECO:0000250, ECO:0000269|PubMed:17974005}.; FUNCTION: [Isoform 5]: May be part of a Golgi-specific membrane cytoskeleton in association with beta-spectrin. {ECO:0000305|PubMed:17974005}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844106_1352995447.666666666667RepeatNote=ANK 2
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844139_1682995447.666666666667RepeatNote=ANK 3
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844172_2012995447.666666666667RepeatNote=ANK 4
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844203_2302995447.666666666667RepeatNote=ANK 5
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844234_2632995447.666666666667RepeatNote=ANK 6
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844267_2962995447.666666666667RepeatNote=ANK 7
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-84473_1022995447.666666666667RepeatNote=ANK 1
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944106_1352932277.6666666666665RepeatNote=ANK 2
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944139_1682932277.6666666666665RepeatNote=ANK 3
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944172_2012932277.6666666666665RepeatNote=ANK 4
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944203_2302932277.6666666666665RepeatNote=ANK 5
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944234_2632932277.6666666666665RepeatNote=ANK 6
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944267_2962932277.6666666666665RepeatNote=ANK 7
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-94473_1022932277.6666666666665RepeatNote=ANK 1
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844106_1352821808.0RepeatNote=ANK 2
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844139_1682821808.0RepeatNote=ANK 3
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844172_2012821808.0RepeatNote=ANK 4
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844203_2302821808.0RepeatNote=ANK 5
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844234_2632821808.0RepeatNote=ANK 6
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-84473_1022821808.0RepeatNote=ANK 1
TgeneTESchr10:61994445chr7:115874587ENST000003582040722_469422.0Compositional biasNote=Cys-rich
TgeneTESchr10:61994445chr7:115874587ENST000003934810722_460413.0Compositional biasNote=Cys-rich
TgeneTESchr10:61994445chr7:115874587ENST0000035820407234_2979422.0DomainLIM zinc-binding 1
TgeneTESchr10:61994445chr7:115874587ENST0000035820407299_3599422.0DomainLIM zinc-binding 2
TgeneTESchr10:61994445chr7:115874587ENST0000035820407362_4219422.0DomainLIM zinc-binding 3
TgeneTESchr10:61994445chr7:115874587ENST000003582040792_1999422.0DomainPET
TgeneTESchr10:61994445chr7:115874587ENST0000039348107234_2970413.0DomainLIM zinc-binding 1
TgeneTESchr10:61994445chr7:115874587ENST0000039348107299_3590413.0DomainLIM zinc-binding 2
TgeneTESchr10:61994445chr7:115874587ENST0000039348107362_4210413.0DomainLIM zinc-binding 3
TgeneTESchr10:61994445chr7:115874587ENST000003934810792_1990413.0DomainPET

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-8441519_18982995447.666666666667Compositional biasNote=Ser-rich
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-8442247_22502995447.666666666667Compositional biasNote=Poly-Thr
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-8442393_23962995447.666666666667Compositional biasNote=Poly-Glu
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-8443205_32112995447.666666666667Compositional biasNote=Poly-Glu
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-8443255_32592995447.666666666667Compositional biasNote=Poly-Pro
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-8443482_34872995447.666666666667Compositional biasNote=Poly-Ser
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-8443785_37912995447.666666666667Compositional biasNote=Poly-Asn
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-8443957_39812995447.666666666667Compositional biasNote=Thr-rich
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-1211519_18980814.0Compositional biasNote=Ser-rich
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-1212247_22500814.0Compositional biasNote=Poly-Thr
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-1212393_23960814.0Compositional biasNote=Poly-Glu
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-1213205_32110814.0Compositional biasNote=Poly-Glu
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-1213255_32590814.0Compositional biasNote=Poly-Pro
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-1213482_34870814.0Compositional biasNote=Poly-Ser
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-1213785_37910814.0Compositional biasNote=Poly-Asn
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-1213957_39810814.0Compositional biasNote=Thr-rich
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-9441519_18982932277.6666666666665Compositional biasNote=Ser-rich
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-9442247_22502932277.6666666666665Compositional biasNote=Poly-Thr
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-9442393_23962932277.6666666666665Compositional biasNote=Poly-Glu
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-9443205_32112932277.6666666666665Compositional biasNote=Poly-Glu
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-9443255_32592932277.6666666666665Compositional biasNote=Poly-Pro
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-9443482_34872932277.6666666666665Compositional biasNote=Poly-Ser
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-9443785_37912932277.6666666666665Compositional biasNote=Poly-Asn
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-9443957_39812932277.6666666666665Compositional biasNote=Thr-rich
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-8441519_18982821808.0Compositional biasNote=Ser-rich
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-8442247_22502821808.0Compositional biasNote=Poly-Thr
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-8442393_23962821808.0Compositional biasNote=Poly-Glu
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-8443205_32112821808.0Compositional biasNote=Poly-Glu
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-8443255_32592821808.0Compositional biasNote=Poly-Pro
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-8443482_34872821808.0Compositional biasNote=Poly-Ser
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-8443785_37912821808.0Compositional biasNote=Poly-Asn
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-8443957_39812821808.0Compositional biasNote=Thr-rich
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-8441141_12882995447.666666666667DomainZU5 2
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-8444090_41742995447.666666666667DomainDeath
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844984_11392995447.666666666667DomainZU5 1
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-1211141_12880814.0DomainZU5 2
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-1214090_41740814.0DomainDeath
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121984_11390814.0DomainZU5 1
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-9441141_12882932277.6666666666665DomainZU5 2
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-9444090_41742932277.6666666666665DomainDeath
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944984_11392932277.6666666666665DomainZU5 1
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-8441141_12882821808.0DomainZU5 2
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-8444090_41742821808.0DomainDeath
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844984_11392821808.0DomainZU5 1
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-8441273_14072995447.666666666667RegionUPA domain
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-1211273_14070814.0RegionUPA domain
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-9441273_14072932277.6666666666665RegionUPA domain
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-8441273_14072821808.0RegionUPA domain
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844300_3292995447.666666666667RepeatNote=ANK 8
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844333_3622995447.666666666667RepeatNote=ANK 9
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844366_3952995447.666666666667RepeatNote=ANK 10
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844399_4282995447.666666666667RepeatNote=ANK 11
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844432_4612995447.666666666667RepeatNote=ANK 12
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844465_4942995447.666666666667RepeatNote=ANK 13
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844498_5272995447.666666666667RepeatNote=ANK 14
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844531_5602995447.666666666667RepeatNote=ANK 15
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844564_5932995447.666666666667RepeatNote=ANK 16
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844597_6262995447.666666666667RepeatNote=ANK 17
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844630_6592995447.666666666667RepeatNote=ANK 18
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844663_6922995447.666666666667RepeatNote=ANK 19
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844696_7252995447.666666666667RepeatNote=ANK 20
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844729_7582995447.666666666667RepeatNote=ANK 21
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844762_7912995447.666666666667RepeatNote=ANK 22
HgeneANK3chr10:61994445chr7:115874587ENST00000280772-844795_8252995447.666666666667RepeatNote=ANK 23
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121106_1350814.0RepeatNote=ANK 2
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121139_1680814.0RepeatNote=ANK 3
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121172_2010814.0RepeatNote=ANK 4
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121203_2300814.0RepeatNote=ANK 5
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121234_2630814.0RepeatNote=ANK 6
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121267_2960814.0RepeatNote=ANK 7
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121300_3290814.0RepeatNote=ANK 8
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121333_3620814.0RepeatNote=ANK 9
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121366_3950814.0RepeatNote=ANK 10
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121399_4280814.0RepeatNote=ANK 11
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121432_4610814.0RepeatNote=ANK 12
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121465_4940814.0RepeatNote=ANK 13
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121498_5270814.0RepeatNote=ANK 14
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121531_5600814.0RepeatNote=ANK 15
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121564_5930814.0RepeatNote=ANK 16
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121597_6260814.0RepeatNote=ANK 17
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121630_6590814.0RepeatNote=ANK 18
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121663_6920814.0RepeatNote=ANK 19
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121696_7250814.0RepeatNote=ANK 20
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121729_7580814.0RepeatNote=ANK 21
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-12173_1020814.0RepeatNote=ANK 1
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121762_7910814.0RepeatNote=ANK 22
HgeneANK3chr10:61994445chr7:115874587ENST00000355288-121795_8250814.0RepeatNote=ANK 23
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944300_3292932277.6666666666665RepeatNote=ANK 8
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944333_3622932277.6666666666665RepeatNote=ANK 9
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944366_3952932277.6666666666665RepeatNote=ANK 10
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944399_4282932277.6666666666665RepeatNote=ANK 11
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944432_4612932277.6666666666665RepeatNote=ANK 12
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944465_4942932277.6666666666665RepeatNote=ANK 13
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944498_5272932277.6666666666665RepeatNote=ANK 14
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944531_5602932277.6666666666665RepeatNote=ANK 15
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944564_5932932277.6666666666665RepeatNote=ANK 16
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944597_6262932277.6666666666665RepeatNote=ANK 17
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944630_6592932277.6666666666665RepeatNote=ANK 18
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944663_6922932277.6666666666665RepeatNote=ANK 19
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944696_7252932277.6666666666665RepeatNote=ANK 20
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944729_7582932277.6666666666665RepeatNote=ANK 21
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944762_7912932277.6666666666665RepeatNote=ANK 22
HgeneANK3chr10:61994445chr7:115874587ENST00000373827-944795_8252932277.6666666666665RepeatNote=ANK 23
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844267_2962821808.0RepeatNote=ANK 7
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844300_3292821808.0RepeatNote=ANK 8
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844333_3622821808.0RepeatNote=ANK 9
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844366_3952821808.0RepeatNote=ANK 10
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844399_4282821808.0RepeatNote=ANK 11
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844432_4612821808.0RepeatNote=ANK 12
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844465_4942821808.0RepeatNote=ANK 13
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844498_5272821808.0RepeatNote=ANK 14
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844531_5602821808.0RepeatNote=ANK 15
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844564_5932821808.0RepeatNote=ANK 16
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844597_6262821808.0RepeatNote=ANK 17
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844630_6592821808.0RepeatNote=ANK 18
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844663_6922821808.0RepeatNote=ANK 19
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844696_7252821808.0RepeatNote=ANK 20
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844729_7582821808.0RepeatNote=ANK 21
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844762_7912821808.0RepeatNote=ANK 22
HgeneANK3chr10:61994445chr7:115874587ENST00000503366-844795_8252821808.0RepeatNote=ANK 23


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Fusion Gene Sequence for ANK3-TES


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>4387_4387_1_ANK3-TES_ANK3_chr10_61994445_ENST00000280772_TES_chr7_115874587_ENST00000358204_length(transcript)=3629nt_BP=1089nt
GGACACCATCATTTGGGTTTTTAAAAGCTTCAGCTTCTCCAGCATCTTTGCATTGTGAATATCTTCCTGCTTCTAGTCAAAGCTTTCTCT
CTAGTGATTGGAATGCTGCTGTAAGCCTGATTAGAGGTGCCTGAGGATATCACCTTTTACAAGGAAGCCGTGTGTGCTTGAGAGGATCTT
TTTAAATGCATTATGGCTCATGCAGCCTCACAATTAAAGAAAAACAGGGATTTAGAAATCAATGCTGAAGAAGAGCCTGAGAAAAAAAGG
AAACACCGCAAACGGTCCCGGGATCGGAAGAAAAAGTCTGATGCCAATGCAAGTTACTTAAGAGCAGCTCGAGCTGGACACCTTGAAAAG
GCCCTCGACTACATAAAAAATGGAGTTGACATCAACATTTGCAATCAGAATGGGTTGAACGCTCTCCACCTTGCTTCCAAAGAAGGCCAT
GTAGAGGTTGTTTCTGAGCTGCTGCAGAGAGAAGCCAATGTGGATGCAGCTACAAAGAAAGGAAACACAGCATTGCACATCGCATCTTTG
GCTGGGCAAGCAGAGGTGGTAAAAGTCTTGGTTACAAATGGAGCCAATGTCAATGCACAATCTCAGAATGGTTTCACGCCATTGTATATG
GCAGCCCAGGAAAATCACCTGGAAGTTGTCAAGTTTCTTCTTGACAATGGTGCAAGCCAGAGCCTAGCCACAGAGGATGGCTTCACACCA
TTGGCAGTGGCTTTGCAACAAGGTCACGACCAAGTCGTTTCGCTCCTGCTAGAGAATGACACCAAAGGAAAAGTGCGTCTCCCAGCTCTT
CATATCGCGGCCCGAAAAGACGACACGAAAGCCGCCGCCCTGCTGCTGCAGAATGACAACAATGCAGATGTGGAATCAAAGAGTGGCTTC
ACTCCGCTCCACATAGCTGCTCACTATGGAAATATCAATGTAGCCACGTTGCTGTTAAACCGAGCGGCTGCTGTGGATTTCACCGCAAGG
AATGACATCACTCCTTTACATGTTGCATCAAAAAGAGGAAATGCAAATATGGTAAAACTATTGCTCGATCGAGGAGCTAAAATCGATGCC
AAAACCAGGATGGGCTTAGGTCACGAGCAAGGATTTGGAGCCCCTTGTTTAAAATGCAAAGAAAAATGTGAAGGATTCGAACTGCACTTC
TGGAGAAAAATATGTCGTAACTGCAAGTGTGGCCAAGAAGAGCATGATGTCCTCTTGAGCAATGAAGAGGATCGAAAAGTGGGAAAACTT
TTTGAAGACACCAAGTATACCACTCTGATTGCAAAACTAAAGTCAGATGGAATTCCCATGTATAAACGCAATGTTATGATATTGACGAAT
CCAGTTGCTGCCAAGAAGAATGTCTCCATCAATACAGTTACCTATGAGTGGGCTCCTCCTGTCCAGAATCAAGCATTGGCCAGGCAGTAC
ATGCAGATGCTACCCAAGGAAAAGCAGCCAGTAGCAGGCTCAGAGGGGGCACAGTACCGGAAGAAGCAGCTGGCAAAGCAGCTCCCTGCA
CATGACCAGGACCCTTCAAAGTGCCATGAGTTGTCTCCCAGAGAGGTGAAGGAGATGGAGCAGTTTGTGAAGAAATATAAGAGCGAAGCT
CTGGGAGTAGGAGATGTCAAACTTCCCTGTGAGATGGATGCCCAAGGCCCCAAACAAATGAACATTCCTGGAGGGGATAGAAGCACCCCA
GCAGCAGTGGGGGCCATGGAGGACAAATCTGCTGAGCACAAAAGAACTCAATATTCCTGCTATTGCTGCAAACTGAGTATGAAAGAAGGT
GACCCAGCCATCTATGCCGAAAGGGCTGGCTATGATAAACTGTGGCACCCAGCTTGTTTTGTCTGCAGCACCTGCCATGAACTCCTGGTT
GACATGATTTATTTTTGGAAGAATGAGAAGCTATACTGTGGCAGACATTACTGTGACAGCGAGAAACCCCGATGTGCTGGCTGTGACGAG
CTGATATTCAGCAATGAGTATACCCAGGCAGAAAACCAGAATTGGCACCTGAAACACTTCTGCTGCTTTGACTGTGATAGCATTCTAGCT
GGGGAGATATACGTGATGGTCAATGACAAGCCCGTGTGCAAGCCCTGCTATGTGAAGAATCACGCTGTGGTGTGTCAAGGATGCCACAAT
GCCATCGACCCAGAAGTGCAGCGGGTGACCTATAACAATTTCAGCTGGCATGCATCCACAGAGTGCTTTCTGTGCTCTTGCTGCAGCAAA
TGCCTCATTGGGCAGAAGTTCATGCCAGTAGAAGGGATGGTTTTCTGTTCAGTGGAATGTAAGAAGAGGATGTCTTAGGAGGAGGGCACC
CAGAAGTATCGAGCCATAGCTATCCAAAGTGGTCTGCATTTCTACTGTAAAATGCAATTTGAAAAAAATAAAACGCAAAAAAAGAAACTG
TAAAGGAAACCAAGAGATTTTGTTTAATTTTTTTGGCCATTTTTTCTTCATCAATTTTTTTTCGGTCTCAACTTTTAAACTTGGTTTAAG
CATTTGATTTGTAAAACAGTAAATAATTGTATCTTTCCATAGCTTTTCAAATGTGAAATCATTTTTGGAAGCTTGGATCTCATTAAACTT
CATGTCTCTATTCCATTTGTGCCACACACTTAAAAGTTAGTGTACTGAATGGAAAGATGAGCATTCCTAGTTCTACACTTCTTTTTTCCC
CCTCATGTGTAAAATGAAAAGAAAACTAAATTTGCCCTAATACCAAGGCGCTACGTTTATTGCCTCGTCTTATTCACTGACCTTTGTAAT
GATACACAGTGAATTCTTTTTGACAAAGAGAAATGCAGTGTAGTATGCAGAGCTGCTGTTTTAATGCCTATGCATTTACTCTTTCCTGAT
TTAGGCAGAGGTGGCATTTTCTTTATTGCATTTCTCTATTTTTTTAATGTACCCTACCTTCAGTATTCTCTTTGTAAGTTGGTGACTTGC
ATCTGTGGCCTTGAATATTTTATTATCACATGTGGCATAACAGTATCCACACTTTTTAGTTCTTTATTTTTTTTTTTTTATTTTGAGCAA
TTCTCCTGCCTCAGCCTCCCAAATAGCTGGGATTACAGGTGCATGCCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGTTT
TCACCATGTTAGCCAGGCTGGTCTCAAACTCCTGACCTCAGATGATCCGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGGG
AGCCACCATGCCTGACCCACACACTTTTTACTTGTATAGATGATTTTTGGCTTGGACATAAAAGCCAAGCCACCCATTTGCTTTTAATCC
AAAGAACATGTATAGTTTTTGTACCCAGAGACTATGATTTATATTGATTGCACTTGCCTGCCATGATTTAGATAAGATTTTTTTTGCATG
GTTTTTATTCTTTCCTAATGGATCCTGTTTTATAATACTTCCAAGCCTGTCCATGGATATATCAAATGTCTTCACTTGTATATTTTCATG
GCTAGGTATTTCTAATGTTTATTCTTCCCTGTGTACTTCTACACATAGCTATGCACTATGAAAATTAAATGGAATGAATGATATGTATAT

>4387_4387_1_ANK3-TES_ANK3_chr10_61994445_ENST00000280772_TES_chr7_115874587_ENST00000358204_length(amino acids)=711AA_BP=299
MAHAASQLKKNRDLEINAEEEPEKKRKHRKRSRDRKKKSDANASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVV
SELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVA
LQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDIT
PLHVASKRGNANMVKLLLDRGAKIDAKTRMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDT
KYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQD
PSKCHELSPREVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAI
YAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIY

--------------------------------------------------------------
>4387_4387_2_ANK3-TES_ANK3_chr10_61994445_ENST00000373827_TES_chr7_115874587_ENST00000358204_length(transcript)=3590nt_BP=1050nt
ACAGCAGGAGGAGGATAGGCCGCGCTGGGCGGGCGTCGCGGGGCCGCGCTTGGTGTTCCTGAGCCGCGGCCGAACTTTTTCCCAAGAAGT
CCCACGTTTGGAGGCCCGAGGAGCGGGACGGGGAGGAGAGACTGGAGTTCCTGGAAGGAGCAGCAGCAGCAGCCCCACAACATGGCCTCC
TCCGCCTCCTCCTCTCCCGCGGGCACCGAGGACTCCGCTCCTGCCCAGGGTGGCTTTGGATCAGATTATTCACGAAGCTCTAGAAAGTCT
GATGCCAATGCAAGTTACTTAAGAGCAGCTCGAGCTGGACACCTTGAAAAGGCCCTCGACTACATAAAAAATGGAGTTGACATCAACATT
TGCAATCAGAATGGGTTGAACGCTCTCCACCTTGCTTCCAAAGAAGGCCATGTAGAGGTTGTTTCTGAGCTGCTGCAGAGAGAAGCCAAT
GTGGATGCAGCTACAAAGAAAGGAAACACAGCATTGCACATCGCATCTTTGGCTGGGCAAGCAGAGGTGGTAAAAGTCTTGGTTACAAAT
GGAGCCAATGTCAATGCACAATCTCAGAATGGTTTCACGCCATTGTATATGGCAGCCCAGGAAAATCACCTGGAAGTTGTCAAGTTTCTT
CTTGACAATGGTGCAAGCCAGAGCCTAGCCACAGAGGATGGCTTCACACCATTGGCAGTGGCTTTGCAACAAGGTCACGACCAAGTCGTT
TCGCTCCTGCTAGAGAATGACACCAAAGGAAAAGTGCGTCTCCCAGCTCTTCATATCGCGGCCCGAAAAGACGACACGAAAGCCGCCGCC
CTGCTGCTGCAGAATGACAACAATGCAGATGTGGAATCAAAGAGTGGCTTCACTCCGCTCCACATAGCTGCTCACTATGGAAATATCAAT
GTAGCCACGTTGCTGTTAAACCGAGCGGCTGCTGTGGATTTCACCGCAAGGAATGACATCACTCCTTTACATGTTGCATCAAAAAGAGGA
AATGCAAATATGGTAAAACTATTGCTCGATCGAGGAGCTAAAATCGATGCCAAAACCAGGATGGGCTTAGGTCACGAGCAAGGATTTGGA
GCCCCTTGTTTAAAATGCAAAGAAAAATGTGAAGGATTCGAACTGCACTTCTGGAGAAAAATATGTCGTAACTGCAAGTGTGGCCAAGAA
GAGCATGATGTCCTCTTGAGCAATGAAGAGGATCGAAAAGTGGGAAAACTTTTTGAAGACACCAAGTATACCACTCTGATTGCAAAACTA
AAGTCAGATGGAATTCCCATGTATAAACGCAATGTTATGATATTGACGAATCCAGTTGCTGCCAAGAAGAATGTCTCCATCAATACAGTT
ACCTATGAGTGGGCTCCTCCTGTCCAGAATCAAGCATTGGCCAGGCAGTACATGCAGATGCTACCCAAGGAAAAGCAGCCAGTAGCAGGC
TCAGAGGGGGCACAGTACCGGAAGAAGCAGCTGGCAAAGCAGCTCCCTGCACATGACCAGGACCCTTCAAAGTGCCATGAGTTGTCTCCC
AGAGAGGTGAAGGAGATGGAGCAGTTTGTGAAGAAATATAAGAGCGAAGCTCTGGGAGTAGGAGATGTCAAACTTCCCTGTGAGATGGAT
GCCCAAGGCCCCAAACAAATGAACATTCCTGGAGGGGATAGAAGCACCCCAGCAGCAGTGGGGGCCATGGAGGACAAATCTGCTGAGCAC
AAAAGAACTCAATATTCCTGCTATTGCTGCAAACTGAGTATGAAAGAAGGTGACCCAGCCATCTATGCCGAAAGGGCTGGCTATGATAAA
CTGTGGCACCCAGCTTGTTTTGTCTGCAGCACCTGCCATGAACTCCTGGTTGACATGATTTATTTTTGGAAGAATGAGAAGCTATACTGT
GGCAGACATTACTGTGACAGCGAGAAACCCCGATGTGCTGGCTGTGACGAGCTGATATTCAGCAATGAGTATACCCAGGCAGAAAACCAG
AATTGGCACCTGAAACACTTCTGCTGCTTTGACTGTGATAGCATTCTAGCTGGGGAGATATACGTGATGGTCAATGACAAGCCCGTGTGC
AAGCCCTGCTATGTGAAGAATCACGCTGTGGTGTGTCAAGGATGCCACAATGCCATCGACCCAGAAGTGCAGCGGGTGACCTATAACAAT
TTCAGCTGGCATGCATCCACAGAGTGCTTTCTGTGCTCTTGCTGCAGCAAATGCCTCATTGGGCAGAAGTTCATGCCAGTAGAAGGGATG
GTTTTCTGTTCAGTGGAATGTAAGAAGAGGATGTCTTAGGAGGAGGGCACCCAGAAGTATCGAGCCATAGCTATCCAAAGTGGTCTGCAT
TTCTACTGTAAAATGCAATTTGAAAAAAATAAAACGCAAAAAAAGAAACTGTAAAGGAAACCAAGAGATTTTGTTTAATTTTTTTGGCCA
TTTTTTCTTCATCAATTTTTTTTCGGTCTCAACTTTTAAACTTGGTTTAAGCATTTGATTTGTAAAACAGTAAATAATTGTATCTTTCCA
TAGCTTTTCAAATGTGAAATCATTTTTGGAAGCTTGGATCTCATTAAACTTCATGTCTCTATTCCATTTGTGCCACACACTTAAAAGTTA
GTGTACTGAATGGAAAGATGAGCATTCCTAGTTCTACACTTCTTTTTTCCCCCTCATGTGTAAAATGAAAAGAAAACTAAATTTGCCCTA
ATACCAAGGCGCTACGTTTATTGCCTCGTCTTATTCACTGACCTTTGTAATGATACACAGTGAATTCTTTTTGACAAAGAGAAATGCAGT
GTAGTATGCAGAGCTGCTGTTTTAATGCCTATGCATTTACTCTTTCCTGATTTAGGCAGAGGTGGCATTTTCTTTATTGCATTTCTCTAT
TTTTTTAATGTACCCTACCTTCAGTATTCTCTTTGTAAGTTGGTGACTTGCATCTGTGGCCTTGAATATTTTATTATCACATGTGGCATA
ACAGTATCCACACTTTTTAGTTCTTTATTTTTTTTTTTTTATTTTGAGCAATTCTCCTGCCTCAGCCTCCCAAATAGCTGGGATTACAGG
TGCATGCCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGTTTTCACCATGTTAGCCAGGCTGGTCTCAAACTCCTGACCTC
AGATGATCCGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGGGAGCCACCATGCCTGACCCACACACTTTTTACTTGTATAG
ATGATTTTTGGCTTGGACATAAAAGCCAAGCCACCCATTTGCTTTTAATCCAAAGAACATGTATAGTTTTTGTACCCAGAGACTATGATT
TATATTGATTGCACTTGCCTGCCATGATTTAGATAAGATTTTTTTTGCATGGTTTTTATTCTTTCCTAATGGATCCTGTTTTATAATACT
TCCAAGCCTGTCCATGGATATATCAAATGTCTTCACTTGTATATTTTCATGGCTAGGTATTTCTAATGTTTATTCTTCCCTGTGTACTTC

>4387_4387_2_ANK3-TES_ANK3_chr10_61994445_ENST00000373827_TES_chr7_115874587_ENST00000358204_length(amino acids)=754AA_BP=342
MGGRRGAALGVPEPRPNFFPRSPTFGGPRSGTGRRDWSSWKEQQQQPHNMASSASSSPAGTEDSAPAQGGFGSDYSRSSRKSDANASYLR
AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQS
QNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNN
ADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRMGLGHEQGFGAPCLKCKE
KCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPV
QNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQMN
IPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSE
KPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTE

--------------------------------------------------------------
>4387_4387_3_ANK3-TES_ANK3_chr10_61994445_ENST00000503366_TES_chr7_115874587_ENST00000358204_length(transcript)=3522nt_BP=982nt
AAGCAGCGGCTGCTTTGCCTGGGGAGCACCCGTAAATGGACTTTGGTCTCAATGCTTTGACTCTTTGCCGTGGTTTTGGATGTTGGAATA
CCGGCGGTGATCTGTCTTTTATAAACTCACCTGATTTAAAGGAAAGATGAGTGAAGAACCAAAGGAGAAAAATGCAAAACCTGCTCATAG
GAAAAGGAAAGGAAAAAAGTCTGATGCCAATGCAAGTTACTTAAGAGCAGCTCGAGCTGGACACCTTGAAAAGGCCCTCGACTACATAAA
AAATGGAGTTGACATCAACATTTGCAATCAGAATGGGTTGAACGCTCTCCACCTTGCTTCCAAAGAAGGCCATGTAGAGGTTGTTTCTGA
GCTGCTGCAGAGAGAAGCCAATGTGGATGCAGCTACAAAGAAAGGAAACACAGCATTGCACATCGCATCTTTGGCTGGGCAAGCAGAGGT
GGTAAAAGTCTTGGTTACAAATGGAGCCAATGTCAATGCACAATCTCAGAATGGTTTCACGCCATTGTATATGGCAGCCCAGGAAAATCA
CCTGGAAGTTGTCAAGTTTCTTCTTGACAATGGTGCAAGCCAGAGCCTAGCCACAGAGGATGGCTTCACACCATTGGCAGTGGCTTTGCA
ACAAGGTCACGACCAAGTCGTTTCGCTCCTGCTAGAGAATGACACCAAAGGAAAAGTGCGTCTCCCAGCTCTTCATATCGCGGCCCGAAA
AGACGACACGAAAGCCGCCGCCCTGCTGCTGCAGAATGACAACAATGCAGATGTGGAATCAAAGAGTGGCTTCACTCCGCTCCACATAGC
TGCTCACTATGGAAATATCAATGTAGCCACGTTGCTGTTAAACCGAGCGGCTGCTGTGGATTTCACCGCAAGGAATGACATCACTCCTTT
ACATGTTGCATCAAAAAGAGGAAATGCAAATATGGTAAAACTATTGCTCGATCGAGGAGCTAAAATCGATGCCAAAACCAGGATGGGCTT
AGGTCACGAGCAAGGATTTGGAGCCCCTTGTTTAAAATGCAAAGAAAAATGTGAAGGATTCGAACTGCACTTCTGGAGAAAAATATGTCG
TAACTGCAAGTGTGGCCAAGAAGAGCATGATGTCCTCTTGAGCAATGAAGAGGATCGAAAAGTGGGAAAACTTTTTGAAGACACCAAGTA
TACCACTCTGATTGCAAAACTAAAGTCAGATGGAATTCCCATGTATAAACGCAATGTTATGATATTGACGAATCCAGTTGCTGCCAAGAA
GAATGTCTCCATCAATACAGTTACCTATGAGTGGGCTCCTCCTGTCCAGAATCAAGCATTGGCCAGGCAGTACATGCAGATGCTACCCAA
GGAAAAGCAGCCAGTAGCAGGCTCAGAGGGGGCACAGTACCGGAAGAAGCAGCTGGCAAAGCAGCTCCCTGCACATGACCAGGACCCTTC
AAAGTGCCATGAGTTGTCTCCCAGAGAGGTGAAGGAGATGGAGCAGTTTGTGAAGAAATATAAGAGCGAAGCTCTGGGAGTAGGAGATGT
CAAACTTCCCTGTGAGATGGATGCCCAAGGCCCCAAACAAATGAACATTCCTGGAGGGGATAGAAGCACCCCAGCAGCAGTGGGGGCCAT
GGAGGACAAATCTGCTGAGCACAAAAGAACTCAATATTCCTGCTATTGCTGCAAACTGAGTATGAAAGAAGGTGACCCAGCCATCTATGC
CGAAAGGGCTGGCTATGATAAACTGTGGCACCCAGCTTGTTTTGTCTGCAGCACCTGCCATGAACTCCTGGTTGACATGATTTATTTTTG
GAAGAATGAGAAGCTATACTGTGGCAGACATTACTGTGACAGCGAGAAACCCCGATGTGCTGGCTGTGACGAGCTGATATTCAGCAATGA
GTATACCCAGGCAGAAAACCAGAATTGGCACCTGAAACACTTCTGCTGCTTTGACTGTGATAGCATTCTAGCTGGGGAGATATACGTGAT
GGTCAATGACAAGCCCGTGTGCAAGCCCTGCTATGTGAAGAATCACGCTGTGGTGTGTCAAGGATGCCACAATGCCATCGACCCAGAAGT
GCAGCGGGTGACCTATAACAATTTCAGCTGGCATGCATCCACAGAGTGCTTTCTGTGCTCTTGCTGCAGCAAATGCCTCATTGGGCAGAA
GTTCATGCCAGTAGAAGGGATGGTTTTCTGTTCAGTGGAATGTAAGAAGAGGATGTCTTAGGAGGAGGGCACCCAGAAGTATCGAGCCAT
AGCTATCCAAAGTGGTCTGCATTTCTACTGTAAAATGCAATTTGAAAAAAATAAAACGCAAAAAAAGAAACTGTAAAGGAAACCAAGAGA
TTTTGTTTAATTTTTTTGGCCATTTTTTCTTCATCAATTTTTTTTCGGTCTCAACTTTTAAACTTGGTTTAAGCATTTGATTTGTAAAAC
AGTAAATAATTGTATCTTTCCATAGCTTTTCAAATGTGAAATCATTTTTGGAAGCTTGGATCTCATTAAACTTCATGTCTCTATTCCATT
TGTGCCACACACTTAAAAGTTAGTGTACTGAATGGAAAGATGAGCATTCCTAGTTCTACACTTCTTTTTTCCCCCTCATGTGTAAAATGA
AAAGAAAACTAAATTTGCCCTAATACCAAGGCGCTACGTTTATTGCCTCGTCTTATTCACTGACCTTTGTAATGATACACAGTGAATTCT
TTTTGACAAAGAGAAATGCAGTGTAGTATGCAGAGCTGCTGTTTTAATGCCTATGCATTTACTCTTTCCTGATTTAGGCAGAGGTGGCAT
TTTCTTTATTGCATTTCTCTATTTTTTTAATGTACCCTACCTTCAGTATTCTCTTTGTAAGTTGGTGACTTGCATCTGTGGCCTTGAATA
TTTTATTATCACATGTGGCATAACAGTATCCACACTTTTTAGTTCTTTATTTTTTTTTTTTTATTTTGAGCAATTCTCCTGCCTCAGCCT
CCCAAATAGCTGGGATTACAGGTGCATGCCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGTTTTCACCATGTTAGCCAGG
CTGGTCTCAAACTCCTGACCTCAGATGATCCGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGGGAGCCACCATGCCTGACC
CACACACTTTTTACTTGTATAGATGATTTTTGGCTTGGACATAAAAGCCAAGCCACCCATTTGCTTTTAATCCAAAGAACATGTATAGTT
TTTGTACCCAGAGACTATGATTTATATTGATTGCACTTGCCTGCCATGATTTAGATAAGATTTTTTTTGCATGGTTTTTATTCTTTCCTA
ATGGATCCTGTTTTATAATACTTCCAAGCCTGTCCATGGATATATCAAATGTCTTCACTTGTATATTTTCATGGCTAGGTATTTCTAATG
TTTATTCTTCCCTGTGTACTTCTACACATAGCTATGCACTATGAAAATTAAATGGAATGAATGATATGTATATTACTCAAAATAAAGTTT

>4387_4387_3_ANK3-TES_ANK3_chr10_61994445_ENST00000503366_TES_chr7_115874587_ENST00000358204_length(amino acids)=694AA_BP=282
MSEEPKEKNAKPAHRKRKGKKSDANASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG
NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDT
KGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLL
LDRGAKIDAKTRMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMY
KRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQ
FVKKYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFV
CSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNH

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Fusion Gene PPI Analysis for ANK3-TES


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ANK3-TES


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ANK3-TES


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneANK3C0005586Bipolar Disorder8CTD_human;PSYGENET
HgeneANK3C0005587Depression, Bipolar3CTD_human
HgeneANK3C0024713Manic Disorder3CTD_human
HgeneANK3C0036341Schizophrenia3PSYGENET
HgeneANK3C0338831Manic3CTD_human
HgeneANK3C0033975Psychotic Disorders2PSYGENET
HgeneANK3C0525045Mood Disorders2PSYGENET
HgeneANK3C0015923Fetal Alcohol Syndrome1CTD_human
HgeneANK3C0024121Lung Neoplasms1CTD_human
HgeneANK3C0033300Progeria1CTD_human
HgeneANK3C0038220Status Epilepticus1CTD_human
HgeneANK3C0178417Anhedonia1PSYGENET
HgeneANK3C0242379Malignant neoplasm of lung1CTD_human
HgeneANK3C0270823Petit mal status1CTD_human
HgeneANK3C0311335Grand Mal Status Epilepticus1CTD_human
HgeneANK3C0349204Nonorganic psychosis1PSYGENET
HgeneANK3C0393734Complex Partial Status Epilepticus1CTD_human
HgeneANK3C0751522Status Epilepticus, Subclinical1CTD_human
HgeneANK3C0751523Non-Convulsive Status Epilepticus1CTD_human
HgeneANK3C0751524Simple Partial Status Epilepticus1CTD_human
HgeneANK3C0814154Alcohol Related Neurodevelopmental Disorder1CTD_human
HgeneANK3C2985290Fetal Alcohol Spectrum Disorders1CTD_human
HgeneANK3C3146244Alcohol Related Birth Defect1CTD_human
HgeneANK3C3661483Partial Fetal Alcohol Syndrome1CTD_human
HgeneANK3C3809672MENTAL RETARDATION, AUTOSOMAL RECESSIVE 371CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneC0017636Glioblastoma1CTD_human
TgeneC0023893Liver Cirrhosis, Experimental1CTD_human
TgeneC0334588Giant Cell Glioblastoma1CTD_human
TgeneC1621958Glioblastoma Multiforme1CTD_human