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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:ANK3-USP9Y (FusionGDB2 ID:HG288TG8287)

Fusion Gene Summary for ANK3-USP9Y

Fusion gene summary

Fusion gene information	Fusion gene name: ANK3-USP9Y
	Fusion gene ID: hg288tg8287
		Hgene	Tgene
	Gene symbol	ANK3	USP9Y
	Gene ID	288	8287
	Gene name	ankyrin 3	ubiquitin specific peptidase 9 Y-linked
	Synonyms	ANKYRIN-G\|MRT37	DFFRY\|SPGFY2
	Cytomap	('ANK3')('USP9Y') 10q21.2	Yq11.221
	Type of gene	protein-coding	protein-coding
	Description	ankyrin-3ankyrin 3, node of Ranvier (ankyrin G)	probable ubiquitin carboxyl-terminal hydrolase FAF-Ydeubiquitinating enzyme FAF-Yfat facets protein-related, Y-linkedubiquitin specific peptidase 9, Y-linked (fat facets-like, Drosophila)ubiquitin thioesterase FAF-Yubiquitin thiolesterase FAF-Yubiqu
	Modification date	20200313	20200320
	UniProtAcc	Q12955	.
	Ensembl transtripts involved in fusion gene	ENST00000280772, ENST00000355288, ENST00000373827, ENST00000503366, ENST00000460468, ENST00000510382,
Fusion gene scores	* DoF score	28 X 22 X 9=5544	8 X 8 X 2=128
	# samples	29	8
	** MAII score	log2(29/5544*10)=-4.25680245212228 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(8/128*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: ANK3 [Title/Abstract] AND USP9Y [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ANK3(61815416)-USP9Y(14968265), # samples:3
Anticipated loss of major functional domain due to fusion event.	ANK3-USP9Y seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ANK3-USP9Y seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ANK3-USP9Y seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ANK3-USP9Y seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across ANK3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across USP9Y (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	PRAD	TCGA-KK-A8IH-01A	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+
ChimerDB4	PRAD	TCGA-KK-A8IH	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+

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Fusion Gene ORF analysis for ANK3-USP9Y

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-3UTR	ENST00000280772	ENST00000426564	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+
5CDS-3UTR	ENST00000355288	ENST00000426564	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+
5CDS-3UTR	ENST00000373827	ENST00000426564	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+
5CDS-3UTR	ENST00000503366	ENST00000426564	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+
In-frame	ENST00000280772	ENST00000338981	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+
In-frame	ENST00000355288	ENST00000338981	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+
In-frame	ENST00000373827	ENST00000338981	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+
In-frame	ENST00000503366	ENST00000338981	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+
intron-3CDS	ENST00000460468	ENST00000338981	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+
intron-3CDS	ENST00000510382	ENST00000338981	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+
intron-3UTR	ENST00000460468	ENST00000426564	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+
intron-3UTR	ENST00000510382	ENST00000426564	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000280772	ANK3	chr10	61815416	-	ENST00000338981	USP9Y	chrY	14968265	+	15284	13257	192	13265	4357
ENST00000373827	ANK3	chr10	61815416	-	ENST00000338981	USP9Y	chrY	14968265	+	7715	5688	24	5696	1890
ENST00000355288	ANK3	chr10	61815416	-	ENST00000338981	USP9Y	chrY	14968265	+	5613	3586	649	3594	981
ENST00000503366	ANK3	chr10	61815416	-	ENST00000338981	USP9Y	chrY	14968265	+	7701	5674	136	5682	1848

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000280772	ENST00000338981	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+	0.00047056	0.9995295
ENST00000373827	ENST00000338981	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+	0.000559468	0.9994405
ENST00000355288	ENST00000338981	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+	0.000472145	0.9995278
ENST00000503366	ENST00000338981	ANK3	chr10	61815416	-	USP9Y	chrY	14968265	+	0.000545283	0.9994547

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Fusion Genomic Features for ANK3-USP9Y

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
ANK3	chr10	61815415	-	USP9Y	chrY	14968264	+	0.000497498	0.99950254
ANK3	chr10	61815415	-	USP9Y	chrY	14968264	+	0.000497498	0.99950254
ANK3	chr10	61815415	-	USP9Y	chrY	14968264	+	0.000497498	0.99950254
ANK3	chr10	61815415	-	USP9Y	chrY	14968264	+	0.000497498	0.99950254

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ANK3-USP9Y

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:61815416/chrY:14968265)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
ANK3 Q12955	.
FUNCTION: In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments. Regulates KCNA1 channel activity in function of dietary Mg(2+) levels, and thereby contributes to the regulation of renal Mg(2+) reabsorption (PubMed:23903368). {ECO:0000250, ECO:0000269\|PubMed:17974005}.; FUNCTION: [Isoform 5]: May be part of a Golgi-specific membrane cytoskeleton in association with beta-spectrin. {ECO:0000305\|PubMed:17974005}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

1519_1898

4355

5447.666666666667

Compositional bias

Note=Ser-rich

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

2247_2250

4355

5447.666666666667

Compositional bias

Note=Poly-Thr

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

2393_2396

4355

5447.666666666667

Compositional bias

Note=Poly-Glu

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

3205_3211

4355

5447.666666666667

Compositional bias

Note=Poly-Glu

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

3255_3259

4355

5447.666666666667

Compositional bias

Note=Poly-Pro

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

3482_3487

4355

5447.666666666667

Compositional bias

Note=Poly-Ser

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

3785_3791

4355

5447.666666666667

Compositional bias

Note=Poly-Asn

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

3957_3981

4355

5447.666666666667

Compositional bias

Note=Thr-rich

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

1519_1898

979

814.0

Compositional bias

Note=Ser-rich

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

2247_2250

979

814.0

Compositional bias

Note=Poly-Thr

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

2393_2396

979

814.0

Compositional bias

Note=Poly-Glu

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

3205_3211

979

814.0

Compositional bias

Note=Poly-Glu

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

3255_3259

979

814.0

Compositional bias

Note=Poly-Pro

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

3482_3487

979

814.0

Compositional bias

Note=Poly-Ser

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

3785_3791

979

814.0

Compositional bias

Note=Poly-Asn

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

3957_3981

979

814.0

Compositional bias

Note=Thr-rich

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

1519_1898

1846

1808.0

Compositional bias

Note=Ser-rich

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

2247_2250

1846

1808.0

Compositional bias

Note=Poly-Thr

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

2393_2396

1846

1808.0

Compositional bias

Note=Poly-Glu

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

3205_3211

1846

1808.0

Compositional bias

Note=Poly-Glu

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

3255_3259

1846

1808.0

Compositional bias

Note=Poly-Pro

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

3482_3487

1846

1808.0

Compositional bias

Note=Poly-Ser

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

3785_3791

1846

1808.0

Compositional bias

Note=Poly-Asn

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

3957_3981

1846

1808.0

Compositional bias

Note=Thr-rich

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

1141_1288

4355

5447.666666666667

Domain

ZU5 2

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

4090_4174

4355

5447.666666666667

Domain

Death

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

984_1139

4355

5447.666666666667

Domain

ZU5 1

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

1141_1288

979

814.0

Domain

ZU5 2

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

4090_4174

979

814.0

Domain

Death

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

984_1139

979

814.0

Domain

ZU5 1

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

1141_1288

1839

2277.6666666666665

Domain

ZU5 2

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

984_1139

1839

2277.6666666666665

Domain

ZU5 1

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

1141_1288

1846

1808.0

Domain

ZU5 2

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

4090_4174

1846

1808.0

Domain

Death

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

984_1139

1846

1808.0

Domain

ZU5 1

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

1273_1407

4355

5447.666666666667

Region

UPA domain

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

1273_1407

979

814.0

Region

UPA domain

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

1273_1407

1839

2277.6666666666665

Region

UPA domain

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

1273_1407

1846

1808.0

Region

UPA domain

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

106_135

4355

5447.666666666667

Repeat

Note=ANK 2

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

139_168

4355

5447.666666666667

Repeat

Note=ANK 3

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

172_201

4355

5447.666666666667

Repeat

Note=ANK 4

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

203_230

4355

5447.666666666667

Repeat

Note=ANK 5

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

234_263

4355

5447.666666666667

Repeat

Note=ANK 6

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

267_296

4355

5447.666666666667

Repeat

Note=ANK 7

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

300_329

4355

5447.666666666667

Repeat

Note=ANK 8

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

333_362

4355

5447.666666666667

Repeat

Note=ANK 9

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

366_395

4355

5447.666666666667

Repeat

Note=ANK 10

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

399_428

4355

5447.666666666667

Repeat

Note=ANK 11

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

432_461

4355

5447.666666666667

Repeat

Note=ANK 12

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

465_494

4355

5447.666666666667

Repeat

Note=ANK 13

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

498_527

4355

5447.666666666667

Repeat

Note=ANK 14

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

531_560

4355

5447.666666666667

Repeat

Note=ANK 15

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

564_593

4355

5447.666666666667

Repeat

Note=ANK 16

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

597_626

4355

5447.666666666667

Repeat

Note=ANK 17

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

630_659

4355

5447.666666666667

Repeat

Note=ANK 18

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

663_692

4355

5447.666666666667

Repeat

Note=ANK 19

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

696_725

4355

5447.666666666667

Repeat

Note=ANK 20

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

729_758

4355

5447.666666666667

Repeat

Note=ANK 21

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

73_102

4355

5447.666666666667

Repeat

Note=ANK 1

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

762_791

4355

5447.666666666667

Repeat

Note=ANK 22

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000280772

795_825

4355

5447.666666666667

Repeat

Note=ANK 23

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

106_135

979

814.0

Repeat

Note=ANK 2

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

139_168

979

814.0

Repeat

Note=ANK 3

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

172_201

979

814.0

Repeat

Note=ANK 4

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

203_230

979

814.0

Repeat

Note=ANK 5

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

234_263

979

814.0

Repeat

Note=ANK 6

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

267_296

979

814.0

Repeat

Note=ANK 7

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

300_329

979

814.0

Repeat

Note=ANK 8

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

333_362

979

814.0

Repeat

Note=ANK 9

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

366_395

979

814.0

Repeat

Note=ANK 10

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

399_428

979

814.0

Repeat

Note=ANK 11

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

432_461

979

814.0

Repeat

Note=ANK 12

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

465_494

979

814.0

Repeat

Note=ANK 13

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

498_527

979

814.0

Repeat

Note=ANK 14

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

531_560

979

814.0

Repeat

Note=ANK 15

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

564_593

979

814.0

Repeat

Note=ANK 16

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

597_626

979

814.0

Repeat

Note=ANK 17

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

630_659

979

814.0

Repeat

Note=ANK 18

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

663_692

979

814.0

Repeat

Note=ANK 19

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

696_725

979

814.0

Repeat

Note=ANK 20

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

729_758

979

814.0

Repeat

Note=ANK 21

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

73_102

979

814.0

Repeat

Note=ANK 1

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

762_791

979

814.0

Repeat

Note=ANK 22

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000355288

795_825

979

814.0

Repeat

Note=ANK 23

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

106_135

1839

2277.6666666666665

Repeat

Note=ANK 2

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

139_168

1839

2277.6666666666665

Repeat

Note=ANK 3

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

172_201

1839

2277.6666666666665

Repeat

Note=ANK 4

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

203_230

1839

2277.6666666666665

Repeat

Note=ANK 5

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

234_263

1839

2277.6666666666665

Repeat

Note=ANK 6

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

267_296

1839

2277.6666666666665

Repeat

Note=ANK 7

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

300_329

1839

2277.6666666666665

Repeat

Note=ANK 8

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

333_362

1839

2277.6666666666665

Repeat

Note=ANK 9

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

366_395

1839

2277.6666666666665

Repeat

Note=ANK 10

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

399_428

1839

2277.6666666666665

Repeat

Note=ANK 11

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

432_461

1839

2277.6666666666665

Repeat

Note=ANK 12

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

465_494

1839

2277.6666666666665

Repeat

Note=ANK 13

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

498_527

1839

2277.6666666666665

Repeat

Note=ANK 14

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

531_560

1839

2277.6666666666665

Repeat

Note=ANK 15

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

564_593

1839

2277.6666666666665

Repeat

Note=ANK 16

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

597_626

1839

2277.6666666666665

Repeat

Note=ANK 17

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

630_659

1839

2277.6666666666665

Repeat

Note=ANK 18

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

663_692

1839

2277.6666666666665

Repeat

Note=ANK 19

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

696_725

1839

2277.6666666666665

Repeat

Note=ANK 20

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

729_758

1839

2277.6666666666665

Repeat

Note=ANK 21

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

73_102

1839

2277.6666666666665

Repeat

Note=ANK 1

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

762_791

1839

2277.6666666666665

Repeat

Note=ANK 22

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

795_825

1839

2277.6666666666665

Repeat

Note=ANK 23

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

106_135

1846

1808.0

Repeat

Note=ANK 2

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

139_168

1846

1808.0

Repeat

Note=ANK 3

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

172_201

1846

1808.0

Repeat

Note=ANK 4

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

203_230

1846

1808.0

Repeat

Note=ANK 5

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

234_263

1846

1808.0

Repeat

Note=ANK 6

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

267_296

1846

1808.0

Repeat

Note=ANK 7

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

300_329

1846

1808.0

Repeat

Note=ANK 8

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

333_362

1846

1808.0

Repeat

Note=ANK 9

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

366_395

1846

1808.0

Repeat

Note=ANK 10

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

399_428

1846

1808.0

Repeat

Note=ANK 11

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

432_461

1846

1808.0

Repeat

Note=ANK 12

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

465_494

1846

1808.0

Repeat

Note=ANK 13

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

498_527

1846

1808.0

Repeat

Note=ANK 14

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

531_560

1846

1808.0

Repeat

Note=ANK 15

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

564_593

1846

1808.0

Repeat

Note=ANK 16

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

597_626

1846

1808.0

Repeat

Note=ANK 17

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

630_659

1846

1808.0

Repeat

Note=ANK 18

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

663_692

1846

1808.0

Repeat

Note=ANK 19

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

696_725

1846

1808.0

Repeat

Note=ANK 20

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

729_758

1846

1808.0

Repeat

Note=ANK 21

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

73_102

1846

1808.0

Repeat

Note=ANK 1

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

762_791

1846

1808.0

Repeat

Note=ANK 22

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000503366

795_825

1846

1808.0

Repeat

Note=ANK 23

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

1519_1898

1839

2277.6666666666665

Compositional bias

Note=Ser-rich

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

2247_2250

1839

2277.6666666666665

Compositional bias

Note=Poly-Thr

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

2393_2396

1839

2277.6666666666665

Compositional bias

Note=Poly-Glu

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

3205_3211

1839

2277.6666666666665

Compositional bias

Note=Poly-Glu

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

3255_3259

1839

2277.6666666666665

Compositional bias

Note=Poly-Pro

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

3482_3487

1839

2277.6666666666665

Compositional bias

Note=Poly-Ser

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

3785_3791

1839

2277.6666666666665

Compositional bias

Note=Poly-Asn

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

3957_3981

1839

2277.6666666666665

Compositional bias

Note=Thr-rich

Hgene

ANK3

chr10:61815416

chrY:14968265

ENST00000373827

4090_4174

1839

2277.6666666666665

Domain

Death

Tgene

USP9Y

chr10:61815416

chrY:14968265

ENST00000338981

1559_1958

2354

2556.0

Domain

Note=USP

Top

Fusion Gene Sequence for ANK3-USP9Y

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>4390_4390_1_ANK3-USP9Y_ANK3_chr10_61815416_ENST00000280772_USP9Y_chrY_14968265_ENST00000338981_length(transcript)=15284nt_BP=13257nt
GGACACCATCATTTGGGTTTTTAAAAGCTTCAGCTTCTCCAGCATCTTTGCATTGTGAATATCTTCCTGCTTCTAGTCAAAGCTTTCTCT
CTAGTGATTGGAATGCTGCTGTAAGCCTGATTAGAGGTGCCTGAGGATATCACCTTTTACAAGGAAGCCGTGTGTGCTTGAGAGGATCTT
TTTAAATGCATTATGGCTCATGCAGCCTCACAATTAAAGAAAAACAGGGATTTAGAAATCAATGCTGAAGAAGAGCCTGAGAAAAAAAGG
AAACACCGCAAACGGTCCCGGGATCGGAAGAAAAAGTCTGATGCCAATGCAAGTTACTTAAGAGCAGCTCGAGCTGGACACCTTGAAAAG
GCCCTCGACTACATAAAAAATGGAGTTGACATCAACATTTGCAATCAGAATGGGTTGAACGCTCTCCACCTTGCTTCCAAAGAAGGCCAT
GTAGAGGTTGTTTCTGAGCTGCTGCAGAGAGAAGCCAATGTGGATGCAGCTACAAAGAAAGGAAACACAGCATTGCACATCGCATCTTTG
GCTGGGCAAGCAGAGGTGGTAAAAGTCTTGGTTACAAATGGAGCCAATGTCAATGCACAATCTCAGAATGGTTTCACGCCATTGTATATG
GCAGCCCAGGAAAATCACCTGGAAGTTGTCAAGTTTCTTCTTGACAATGGTGCAAGCCAGAGCCTAGCCACAGAGGATGGCTTCACACCA
TTGGCAGTGGCTTTGCAACAAGGTCACGACCAAGTCGTTTCGCTCCTGCTAGAGAATGACACCAAAGGAAAAGTGCGTCTCCCAGCTCTT
CATATCGCGGCCCGAAAAGACGACACGAAAGCCGCCGCCCTGCTGCTGCAGAATGACAACAATGCAGATGTGGAATCAAAGAGTGGCTTC
ACTCCGCTCCACATAGCTGCTCACTATGGAAATATCAATGTAGCCACGTTGCTGTTAAACCGAGCGGCTGCTGTGGATTTCACCGCAAGG
AATGACATCACTCCTTTACATGTTGCATCAAAAAGAGGAAATGCAAATATGGTAAAACTATTGCTCGATCGAGGAGCTAAAATCGATGCC
AAAACCAGGGATGGTCTGACACCACTGCACTGTGGAGCAAGGAGTGGCCACGAGCAGGTGGTAGAAATGTTGCTTGATCGAGCTGCCCCC
ATTCTTTCAAAAACCAAGAATGGATTATCTCCATTGCACATGGCCACACAAGGGGATCATTTAAACTGCGTCCAGCTTCTCCTCCAGCAT
AATGTACCCGTGGATGATGTCACCAATGACTACCTGACTGCCCTACACGTGGCTGCCCACTGTGGCCATTACAAAGTTGCCAAGGTTCTC
TTGGATAAGAAAGCTAACCCCAATGCCAAAGCCCTGAATGGCTTTACCCCTCTTCATATTGCCTGCAAGAAGAATCGAATTAAAGTAATG
GAACTCCTTCTGAAACACGGTGCATCCATCCAAGCTGTAACCGAGTCGGGCCTTACCCCAATCCATGTTGCTGCCTTCATGGGGCATGTA
AATATTGTATCACAACTAATGCATCATGGAGCCTCACCAAACACCACCAATGTGAGAGGAGAAACAGCACTGCACATGGCAGCTCGCTCC
GGCCAAGCTGAAGTTGTGCGGTATCTGGTACAAGACGGAGCTCAGGTAGAAGCTAAAGCTAAGGATGACCAAACACCACTCCACATTTCA
GCCCGACTGGGGAAAGCAGACATAGTACAACAGCTGTTGCAGCAAGGGGCATCTCCAAATGCAGCCACAACTTCTGGGTACACCCCACTT
CACCTTTCCGCCCGAGAGGGGCATGAGGATGTGGCCGCGTTCCTTTTGGATCATGGAGCGTCTTTATCTATAACAACAAAGAAAGGATTT
ACTCCTCTTCATGTGGCAGCAAAATATGGAAAGCTTGAAGTCGCCAATCTCCTGCTACAGAAAAGTGCATCTCCAGATGCTGCTGGGAAG
AGCGGGCTAACACCACTGCATGTAGCTGCACATTACGATAATCAGAAAGTGGCCCTTCTGCTTTTGGACCAAGGAGCCTCACCTCACGCA
GCCGCAAAGAATGGTTATACGCCACTGCACATCGCTGCCAAAAAGAACCAGATGGACATAGCGACAACTCTGCTGGAATATGGTGCTGAT
GCCAACGCAGTTACCCGGCAAGGAATTGCTTCCGTCCATCTCGCAGCTCAGGAAGGGCACGTGGACATGGTGTCGCTGCTCCTCGGTAGA
AATGCGAATGTGAACCTGAGCAATAAGAGCGGCCTGACCCCACTCCATTTGGCTGCTCAAGAAGATCGAGTGAATGTGGCAGAAGTCCTC
GTAAACCAAGGGGCTCATGTGGACGCCCAGACAAAGATGGGATACACACCACTGCATGTGGGCTGCCACTATGGAAATATCAAGATTGTT
AATTTCCTGCTCCAGCATTCTGCAAAAGTTAATGCCAAAACAAAGAATGGGTATACGCCATTACATCAAGCAGCACAGCAGGGGCATACG
CATATAATAAATGTCTTACTTCAGAACAACGCCTCCCCCAATGAACTCACTGTGAATGGGAATACTGCCCTTGGCATTGCCCGGCGCCTC
GGCTACATCTCAGTAGTGGACACCCTGAAGATAGTGACCGAAGAGACCATGACCACAACTACTGTCACAGAGAAGCACAAAATGAATGTT
CCAGAAACGATGAATGAAGTTCTTGATATGTCTGATGATGAAGTTCGTAAAGCCAATGCCCCTGAAATGCTCAGTGATGGCGAATATATC
TCAGATGTTGAAGAAGGTGAAGATGCAATGACCGGGGACACAGACAAATATCTTGGGCCACAGGACCTTAAGGAATTGGGTGATGATTCC
CTGCCTGCAGAGGGTTACATGGGCTTTAGTCTCGGAGCGCGTTCTGCCAGCCTCCGCTCCTTCAGTTCGGATAGGTCTTACACCTTGAAC
AGAAGCTCCTATGCACGGGACAGCATGATGATTGAAGAACTCCTTGTGCCATCCAAAGAGCAGCATCTAACATTCACAAGGGAATTTGAT
TCAGATTCTCTTAGACATTACAGCTGGGCTGCAGACACCTTAGACAATGTCAATCTTGTTTCAAGCCCCATTCATTCTGGGTTTCTGGTT
AGCTTTATGGTGGACGCGAGAGGGGGCTCCATGAGAGGAAGCCGTCATCACGGGATGAGAATCATCATTCCTCCACGCAAGTGTACGGCC
CCCACTCGAATCACCTGCCGTTTGGTAAAGAGACATAAACTGGCCAACCCACCCCCCATGGTGGAAGGAGAGGGATTAGCCAGTAGGCTG
GTAGAAATGGGTCCTGCAGGGGCACAATTTTTAGGCCCTGTCATAGTGGAAATCCCTCACTTTGGGTCCATGAGAGGAAAAGAGAGAGAA
CTCATTGTTCTTCGAAGTGAAAATGGTGAAACTTGGAAGGAGCATCAGTTTGACAGCAAAAATGAAGATTTAACCGAGTTACTTAATGGC
ATGGATGAAGAACTTGATAGCCCAGAAGAGTTAGGGAAAAAGCGTATCTGCAGGATTATCACGAAAGATTTCCCCCAGTATTTTGCAGTG
GTTTCCCGGATTAAGCAGGAAAGCAACCAGATTGGTCCTGAAGGTGGAATTCTGAGCAGCACCACAGTGCCCCTTGTTCAAGCATCTTTC
CCAGAGGGTGCCCTAACTAAAAGAATTCGAGTGGGCCTCCAGGCCCAGCCTGTTCCAGATGAAATTGTGAAAAAGATCCTTGGAAACAAA
GCAACTTTTAGCCCAATTGTCACTGTGGAACCAAGAAGACGGAAATTCCATAAACCAATCACAATGACCATTCCGGTGCCCCCGCCCTCA
GGAGAAGGTGTATCCAATGGATACAAAGGGGACACTACACCCAATCTGCGTCTTCTCTGTAGCATTACAGGGGGCACTTCGCCTGCTCAG
TGGGAAGACATCACAGGAACAACTCCTTTGACGTTTATAAAAGATTGTGTCTCCTTTACAACCAATGTTTCAGCCAGATTTTGGCTTGCA
GACTGCCATCAAGTTTTAGAAACTGTGGGGTTAGCCACGCAACTGTACAGAGAATTGATATGTGTTCCATATATGGCCAAGTTTGTTGTT
TTTGCCAAAATGAATGATCCCGTAGAATCTTCCTTGCGATGTTTCTGCATGACAGATGACAAAGTGGACAAAACTTTAGAGCAACAAGAG
AATTTTGAGGAAGTCGCAAGAAGCAAAGATATTGAGGTTCTGGAAGGAAAACCTATTTATGTTGATTGTTATGGAAATTTGGCCCCACTT
ACCAAAGGAGGACAGCAACTTGTTTTTAACTTTTATTCTTTCAAAGAAAATAGACTGCCATTTTCCATCAAGATTAGAGACACCAGCCAA
GAGCCCTGTGGTCGTCTGTCTTTTCTGAAAGAACCAAAGACAACAAAAGGACTGCCTCAAACAGCGGTTTGCAACTTAAATATCACTCTG
CCAGCACATAAAAAGGAGACAGAGTCAGATCAAGATGATGAGATTGAGAAAACAGATAGACGACAGAGCTTCGCATCCTTAGCTTTACGT
AAGCGCTACAGCTACTTGACTGAGCCTGGAATGATTGAACGGAGTACAGGAGCAACAAGATCCCTCCCCACCACTTACTCATACAAGCCA
TTCTTTTCTACAAGACCATACCAGTCCTGGACAACAGCTCCGATTACAGTGCCTGGGCCAGCCAAGTCAGGCTTCACTTCCTTATCAAGT
TCTTCCTCTAATACGCCATCAGCTTCTCCGTTAAAATCAATATGGTCTGTTTCGACACCTTCTCCAATCAAATCCACATTAGGCGCGTCA
ACTACATCTTCAGTTAAATCCATTAGTGACGTGGCATCTCCAATTAGATCCTTTCGGACAATGTCTTCGCCGATAAAAACTGTGGTGTCA
CAATCTCCATACAATATCCAAGTTTCCTCTGGTACCCTGGCTAGAGCTCCAGCAGTCACGGAAGCTACGCCCTTAAAAGGGCTGGCATCC
AATTCTACGTTTTCCTCTCGAACCTCTCCAGTGACTACAGCAGGGTCTCTTTTGGAGAGGTCATCAATTACTATGACACCCCCTGCCTCC
CCCAAATCAAACATTAATATGTATTCCTCAAGTTTGCCATTTAAGTCAATTATTACATCAGCAGCACCGCTAATATCTTCACCTTTAAAG
TCAGTGGTGTCTCCAGTTAAATCAGCAGTTGATGTCATTTCATCAGCCAAAATTACAATGGCATCTTCTCTCTCATCACCTGTGAAGCAG
ATGCCTGGACATGCAGAGGTAGCATTAGTCAATGGATCTATTTCCCCTCTAAAATATCCATCATCCTCAACTTTAATTAATGGATGCAAA
GCCACTGCCACGTTACAGGAAAAAATTTCTTCTGCTACAAACTCTGTGAGCTCTGTGGTCAGTGCAGCCACTGACACAGTTGAGAAAGTG
TTTTCTACCACGACTGCAATGCCATTTTCCCCACTCAGGTCATATGTTTCTGCAGCACCATCAGCTTTTCAGTCTCTAAGAACTCCTTCC
GCAAGTGCACTCTATACATCCCTTGGGTCGTCAATATCTGCAACTACCTCATCTGTAACTTCATCAATTATAACAGTGCCAGTATACTCT
GTAGTCAATGTTTTGCCAGAACCAGCATTAAAGAAACTTCCAGACTCTAATTCATTTACAAAATCAGCAGCAGCCTTGCTGTCACCCATT
AAAACATTGACTACGGAGACACATCCTCAGCCTCACTTCAGTCGAACTTCATCTCCAGTTAAGTCATCTTTGTTCCTTGCACCCTCTGCC
CTTAAGTTGTCTACACCATCTTCTTTATCTTCCAGTCAGGAGATACTAAAAGATGTAGCTGAAATGAAAGAGGACCTAATGCGGATGACC
GCAATACTACAGACAGATGTGCCTGAGGAGAAGCCATTCCAACCTGAACTCCCAAAGGAAGGGAGAATAGATGATGAAGAACCTTTCAAA
ATTGTAGAGAAAGTAAAGGAAGACTTAGTGAAAGTTAGTGAAATCCTTAAAAAGGATGTATGTGTAGATAATAAAGGATCACCCAAATCA
CCAAAGAGTGACAAAGGACACTCTCCTGAAGATGACTGGATAGAATTTAGTTCGGAAGAAATCCGGGAAGCCAGACAACAAGCTGCTGCG
AGCCAGTCTCCATCTCTGCCAGAGAGAGTGCAAGTAAAAGCAAAAGCCGCCTCCGAAAAGGATTATAACTTGACCAAAGTTATTGATTAC
CTAACAAATGATATTGGGAGTAGTTCACTGACAAACTTAAAATACAAGTTTGAGGATGCAAAGAAGGATGGTGAGGAGAGACAGAAAAGA
GTTTTAAAACCAGCAATTGCTTTGCAGGAACACAAACTCAAAATGCCTCCAGCCTCCATGAGGACTTCCACCTCTGAGAAAGAATTGTGT
AAAATGGCTGATTCCTTTTTTGGAACAGATACTATTTTAGAGTCTCCTGATGACTTTTCTCAACACGACCAAGATAAAAGTCCCTTGTCT
GACAGTGGCTTTGAAACAAGAAGTGAAAAGACACCTTCAGCCCCACAAAGCGCTGAAAGCACTGGTCCTAAACCACTTTTTCATGAAGTT
CCCATCCCTCCTGTCATTACAGAAACAAGAACTGAAGTGGTTCATGTTATCAGGAGCTATGATCCCTCAGCTGGGGATGTTCCCCAGACC
CAACCAGAGGAGCCTGTGTCACCTAAACCTTCACCTACTTTTATGGAATTGGAACCAAAGCCCACCACCTCTAGTATTAAAGAAAAGGTT
AAAGCATTTCAAATGAAAGCCAGTAGTGAAGAAGATGACCACAATCGGGTTTTAAGCAAAGGCATGCGTGTTAAAGAAGAGACTCACATA
ACCACAACCACCAGAATGGTTTATCATTCTCCACCAGGCGGTGAAGGTGCATCTGAAAGAATTGAAGAAACCATGTCAGTCCATGACATC
ATGAAGGCCTTTCAGTCCGGGCGGGATCCTTCCAAAGAACTGGCAGGTCTGTTTGAACATAAGTCGGCAGTGTCTCCAGATGTTCACAAG
TCTGCTGCTGAAACCTCAGCCCAGCATGCAGAGAAGGACAACCAAATGAAACCCAAACTGGAGCGTATAATAGAAGTCCACATCGAAAAA
GGTAACCAAGCTGAGCCCACTGAAGTCATTATTAGAGAAACCAAAAAGCATCCAGAAAAAGAAATGTATGTATATCAGAAAGACTTATCC
CGGGGAGATATTAACCTAAAAGATTTTCTGCCAGAAAAACACGATGCTTTTCCTTGTTCAGAGGAACAGGGTCAGCAAGAAGAAGAAGAA
CTTACTGCTGAAGAGTCATTGCCTTCTTATCTGGAGTCTTCCAGAGTAAACACTCCTGTGTCCCAAGAAGAAGATAGCCGCCCTAGTTCT
GCTCAACTCATATCTGATGACTCTTATAAAACATTGAAGCTTTTGAGTCAACACTCAATAGAATACCATGACGATGAGTTGTCAGAACTA
AGAGGGGAGTCTTACAGGTTTGCTGAGAAAATGCTTCTGTCAGAAAAGCTAGATGTGTCTCATTCTGATACTGAGGAATCGGTTACAGAC
CATGCAGGACCCCCTAGCTCAGAGTTACAGGGGTCTGATAAGCGGTCCAGAGAAAAAATAGCCACTGCCCCCAAAAAAGAAATTCTCTCC
AAAATCTATAAAGATGTTTCTGAAAATGGTGTAGGTAAAGTGTCTAAAGATGAGCATTTTGATAAAGTGACAGTGTTGCACTATTCTGGC
AATGTTAGTAGTCCAAAACATGCCATGTGGATGCGCTTTACTGAGGACAGATTAGACAGAGGTAGAGAGAAGTTGATATATGAAGATAGG
GTGGACAGGACTGTGAAGGAGGCTGAAGAAAAACTGACTGAAGTGTCACAGTTTTTTCGTGACAAAACTGAAAAGCTAAATGATGAACTG
CAGTCCCCAGAGAAAAAGGCACGCCCTAAAAATGGCAAAGAATATTCTTCTCAAAGCCCTACCAGTAGCAGCCCTGAGAAAGTGCTACTG
ACAGAACTGCTGGCATCCAATGATGAGTGGGTTAAGGCAAGACAGCATGGCCCTGATGGACAAGGCTTCCCCAAGGCCGAGGAGAAGGCA
CCCAGTCTGCCCAGCAGCCCAGAGAAGATGGTTCTCTCCCAACAGACTGAGGACAGCAAGTCCACAGTGGAAGCCAAAGGAAGTATTTCA
CAGAGCAAAGCACCAGATGGGCCCCAGTCTGGATTCCAGCTCAAACAATCTAAACTCAGTTCCATTAGATTAAAATTTGAACAAGGCACA
CACGCAAAAAGTAAGGACATGTCTCAAGAAGACAGAAAGTCAGATGGCCAGTCCAGAATCCCAGTTAAAAAAATACAGGAGAGCAAGCTA
CCCGTCTACCAAGTTTTTGCTAGAGAAAAACAGCAGAAGGCCATAGACCTCCCAGATGAAAGTGTATCTGTGCAAAAAGATTTTATGGTA
TTAAAAACCAAAGATGAGCATGCCCAAAGCAACGAAATTGTTGTAAATGATTCTGGCTCTGATAATGTGAAAAAACAGAGAACTGAAATG
TCAAGTAAAGCAATGCCTGACTCTTTTTCTGAGCAGCAGGCTAAAGACTTGGCATGTCATATAACCTCAGATTTAGCAACTAGGGGACCA
TGGGACAAAAAGGTCTTTAGAACATGGGAGAGTTCGGGAGCCACTAACAATAAGTCTCAGAAAGAAAAACTTTCGCATGTACTTGTTCAT
GATGTAAGAGAGAATCACATTGGTCACCCTGAGAGTAAAAGTGTTGATCAAAAGAATGAATTTATGTCTGTGACTGAGAGAGAACGCAAA
TTGTTAACAAACGGCTCTCTCTCAGAAATTAAAGAAATGACTGTAAAATCTCCCTCCAAAAAAGTCTTATATAGGGAATATGTTGTGAAA
GAAGGGGACCATCCAGGCGGATTGCTTGATCAGCCTTCCAGGAGGAGCGAGAGCTCAGCAGTGTCACACATTCCCGTCAGAGTTGCTGAT
GAGAGGAGAATGCTGTCTTCTAATATTCCCGATGGTTTTTGTGAACAGTCGGCATTTCCAAAACATGAACTATCACAAAAATTGTCCCAG
TCAAGCATGAGTAAAGAGACAGTTGAGACACAGCACTTTAATTCTATAGAAGATGAAAAAGTTACCTATTCAGAAATCAGCAAAGTTTCC
AAACACCAGAGTTATGTAGGTTTATGCCCACCTCTCGAGGAAACCGAAACCTCCCCCACCAAATCTCCTGATTCTTTAGAGTTTAGCCCA
GGAAAGGAATCTCCCTCTAGTGATGTATTCGACCACAGTCCCATTGATGGATTGGAAAAACTCGCACCACTAGCCCAGACAGAGGGAGGG
AAAGAGATAAAAACTTTACCCGTTTATGTCAGTTTTGTACAAGTGGGGAAGCAATATGAAAAGGAGATACAACAAGGAGGTGTAAAAAAA
ATCATAAGTCAGGAATGTAAGACAGTACAAGAAACCAGGGGGACCTTTTATACAACTAGACAGCAAAAGCAACCTCCTTCTCCCCAAGGT
AGTCCAGAAGATGATACTCTAGAGCAAGTATCCTTTCTAGACAGCTCTGGGAAAAGCCCTTTAACCCCAGAAACACCCAGTTCAGAGGAA
GTGAGTTATGAATTTACATCTAAGACACCTGACTCGCTCATAGCTTATATACCAGGCAAACCCAGCCCAATTCCCGAGGTTTCTGAGGAG
TCAGAGGAGGAGGAACAGGCCAAGTCAACCTCCCTTAAGCAGACTACAGTGGAGGAAACAGCAGTTGAGCGTGAAATGCCTAATGACGTG
AGCAAAGACTCTAACCAAAGACCCAAAAATAACAGAGTTGCCTATATTGAATTTCCCCCTCCTCCACCACTGGATGCGGACCAGATTGAG
TCAGATAAGAAGCATCATTATCTCCCAGAAAAAGAGGTTGACATGATTGAAGTCAATCTGCAAGATGAGCATGACAAGTACCAGCTGGCT
GAACCTGTCATTAGAGTGCAGCCACCTTCACCAGTTCCTCCCGGGGCAGACGTCAGTGATTCAAGCGATGACGAATCTATTTATCAGCCA
GTCCCAGTTAAAAAATATACCTTCAAATTAAAGGAAGTGGACGATGAACAAAAAGAAAAACCCAAAGCTTCTGCTGAAAAGGCTTCCAAC
CAGAAAGAACTGGAAAGTAATGGATCTGGAAAAGATAATGAATTTGGCCTTGGCCTTGATTCACCTCAGAATGAAATTGCCCAGAATGGG
AACAACGACCAGTCCATCACAGAGTGTTCCATTGCCACCACAGCAGAGTTTTCTCATGACACGGATGCCACAGAGATCGACTCTCTGGAT
GGCTATGACCTGCAAGATGAAGATGATGGCTTGACAGAGAGTGATTCTAAACTCCCAATTCAAGCCATGGAAATTAAGAAAGATATCTGG
AACACAGAGGGCATTCTGAAGCCAGCTGACCGCTCTTTTAGCCAAAGTAAACTTGAAGTTATCGAGGAGGAGGGAAAGGTGGGACCAGAT
GAGGACAAGCCACCTTCTAAAAGTTCTTCATCTGAAAAGACTCCTGATAAGACTGATCAGAAGTCAGGGGCCCAGTTCTTCACACTGGAA
GGCAGACATCCTGACAGATCAGTGTTTCCTGATACTTACTTCAGTTACAAAGTAGATGAAGAATTTGCCACTCCTTTTAAAACAGTAGCT
ACCAAAGGTCTAGATTTTGACCCTTGGTCTAATAACCGAGGGGATGATGAAGTTTTTGACAGTAAATCACGGGAAGATGAAACTAAGCCA
TTTGGGCTGGCGGTAGAAGACCGCTCTCCAGCAACAACCCCTGATACAACGCCAGCCAGAACGCCAACTGATGAAAGTACCCCAACTAGT
GAGCCTAACCCCTTCCCATTTCATGAAGGAAAAATGTTTGAGATGACTCGCAGTGGTGCAATTGACATGAGCAAGAGGGATTTTGTTGAA
GAGAGGCTCCAATTTTTCCAGATTGGTGAGCATACTTCTGAAGGGAAGTCAGGGGACCAGGGGGAAGGGGATAAAAGTATGGTCACTGCC
ACACCACAGCCACAGTCAGGGGACACCACTGTAGAAACCAATCTAGAGAGAAATGTAGAGACACCTACAGTGGAACCTAACCCCAGCATC
CCGACCAGCGGAGAGTGTCAGGAAGGCACATCCAGTAGTGGCTCCCTGGAGAAATCAGCAGCAGCCACTAACACCTCTAAAGTTGACCCC
AAGTTGCGCACGCCTATAAAAATGGGAATTTCTGCATCCACCATGACCATGAAGAAAGAAGGCCCTGGAGAAATAACAGATAAGATAGAA
GCGGTGATGACCAGTTGTCAGGGATTAGAAAATGAAACTATAACAATGATTTCAAATACAGCCAATAGCCAGATGGGCGTTAGGCCCCAT
GAAAAACATGATTTTCAAAAAGATAACTTTAATAACAACAACAATTTGGATTCTTCCACTATACAGACAGATAACATTATGAGTAATATA
GTTCTGACAGAACATTCTGCACCCACTTGTACCACAGAGAAAGATAACCCAGTGAAAGTCTCATCAGGAAAAAAGACAGGGGTACTACAA
GGACACTGTGTAAGAGATAAGCAGAAAGTTCTTGGAGAACAGCAAAAAACAAAGGAATTGATAGGGATTAGGCAAAAATCCAAACTTCCC
ATAAAGGCCACTTCACCAAAAGATACCTTCCCACCGAACCATATGTCAAACACTAAAGCAAGTAAAATGAAGCAGGTTAGTCAATCCGAG
AAAACCAAAGCCCTTACTACTTCTTCATGTGTAGATGTAAAGTCCAGAATTCCAGTGAAAAACACACACAGGGATAACATAATTGCAGTT
AGAAAAGCATGTGCCACACAAAAGCAAGGGCAGCCAGAGAAAGGCAAGGCCAAACAGCTTCCATCCAAGTTGCCAGTAAAGGTAAGATCC
ACCTGTGTCACTACCACCACCACCACTGCCACCACCACCACCACTACCACCACTACCACCACCACCAGCTGCACAGTTAAAGTTAGGAAA
AGTCAGCTCAAGGAAGTATGTAAACATTCCATTGAATATTTTAAGGGAATTAGTGGTGAGACCTTAAAGCTTGTGGACCGCCTCTCTGAA
GAAGAAAAAAAGATGCAGTCCGAGTTGTCCGATGAGGAAGAAAGTACCTCAAGAAACACGTCGTTGTCCGAGACTTCCCGGGGTGGCCAG
CCTTCGGTTACAACGAAGTCTGCTAGAGATAAGAAAACAGAGGCAGCACCTTTAAAATCAAAGAGTGAAAAGGCCGGCAGTGAGAAAAGG
AGCAGTAGAAGGACTGGTCCACAGAGTCCATGTGAACGGACAGATATCAGGATGGCAATAGTAGCCGATCACCTGGGACTTAGTTGGACA
GAACTGGCAAGGGAACTGAATTTTTCAGTGGATGAAATCAATCAAATACGTGTGGAAAATCCAAATTCTTTAATTTCTCAGAGCTTCATG
TTATTAAAAAAATGGGTTACCAGAGACGGAAAAAATGCCACAACTGATGCCTTAACTTCGGTCTTGACAAAAATTAATCGAATAGATATA
GTGACACTGCTAGAAGGACCAATATTTGATTATGGAAATATTTCAGGCACCAGAAGTTTTGCAGATGAGAACAATGTTTTCCATGACCCT
GTTGATGGTTGGCAGAATGAGACATCAAGTGGAAACCTAGAGTCCTGCGCTCAAGCTCGAAGAGTAACTGGTGGGTTACTAGATCGACTG
GATGACAGCCCTGACCAGTGTAGAGATTCCATTACCTCATATCTCAAAGGAGAAGCTGGCAAATTTGAAGCAAATGGAAGCCATACAGAA
ATCACTCCAGAAGCAAAGACAAAATCTTACTTTCCAGAATCCCAAAATGATGTAGGAAAACAGAGTACCAAGGAAACTCTGAAACCAAAA
ATACATGGATCTGGTCATGTTGAAGAACCAGCATCACCACTAGCAGCATATCAGAAATCTCTAGAAGAAACCAGCAAGCTTATAATAGAA
GAGACTAAACCCTGTGTGCCTGTCAGTATGAAAAAGATGAGTAGGACTTCTCCAGCAGATGGCAAGCCAAGGCTTAGCCTCCATGAAGAA
GAGGGGTCCAGTGGGTCTGAGCAAAAGAATTCATAATGCACTTAAAGGAATTCCAGATGACAGAGATGGGCTGTTCGATACAATACAGCG
CTCGAAGAATCACTATCAAAAACGAGCATATCAGTGCATAAAATGTATGGTAGCTCTATTTAGCAGTTGTCCTGTTGCTTACCAGATCTT
ACAGGGTAACGGAGATCTTAAAAGAAAATGGACCTGGGCAGTGGAATGGCTAGGAGATGAACTTGAAAGAAGACCATATACTGGCAATCC
TCAGTATAGTTACAACAATTGGTCTCCTCCAGTACAAAGCAATGAAACAGCAAATGGTTATTTCTTAGAAAGATCACATAGTGCTAGGAT
GACACTTGCAAAAGCTTGTGAACTCTGTCCAGAAGAGGAGCCAGATGACCAGGATGCCCCAGATGAGCATGAGCCCTCTCCATCAGAAGA
TGCCCCATTATATCCTCATTCACCTGCCTCTCAGTATCAACAGAATAATCATGTACATGGACAGCCATATACAGGACCAGCAGCACATCA
CTTGAACAACCCTCAGAAAACAGGCCAACGAACACAAGAAAATTATGAAGGCAATGAAGAAGTATCCTCACCTCAGATGAAGGATCAGTG
AAAAGCAATAATTAACTGCTTCCTTTATGACTATGCACTAAGGTCTTATAGTCCAAACTTTCTCTGTGTCTGGCTAGTATTGAAAACTAG
ATAAACTGCTCCAAACCAACATGGAGTAAAGAGCATATTCACTGGTTTATTTGCAGTAATTTGCAATTTGTCAGTGTATAAGACACATGC
AGGGTGAAGTGTACAGAGTTTTGTAACAAATGACTGGTCCTAATCTGTAAATGAGAAAGGTATATATACTATGTTAATGTCTGACTGTTA
ATTCTTAAGCAAGAAACTTTTTTTGATGAAAACAAGTCAGATCTACACAGTCACACAATTATTTTTTGTTGTGTTCACTACATTGTGCAA
TTGATATTGCCTGCTTTGAGCAGTTTGGTCAACTTACCAACTTCCCCCCAAAAAAGGGAACATAAAAGAGCCCATCTTTGTCAGTTTACA
CCAATAGTTTCTTGTTAATCCTTCTTTCCTGGATATATAAGGCTGGTGGTAACTTTTGAATTATATGGTTGATGTGGAAAATTGGCAGTG
TAACATTTCTAGATACTTTTCATTACCTTTTTATTCTGGTATATAGGCTAACCACTTTAAAGCTATTCTTATGCTGTAACAGTTAGCATG
GCTTCACACTGTTTGTGTAGCCAAGAGGACAGAATTACATGAATGACAGTGCCCAGAGTGACAGCTGTATATTGCTCAGAGCTTTTATTT
CTTATACCTAGAATAAATATAAAATGGGGGAAAAATGTGACAGACAAGCAGTTTTTCATTGCACACATATTCTTCACATTTAATGTTTGA
TAGTTCAATTTCTTGAGCTGAAGAATATCAAAGTATCGATAATACGAATTTTAAAATATTAAAACCAATACACAAAATTTTCCTATGTCA
GAATGTGGTGGAGCATAATAGATTGTATTTGGTGTGCTTGCGATTTTTTTTTTCCATAGAATTTATTAAGTGAAGTTTCTAAAACTTTGC
TTCTCCTGATCCCGGTGAAGTGTACATCATAAGAATCCATAGTACTTTGAAGTACCATTGCACCAAGATGTCTGACTGAATTCATAGTCA
CACTTTTATTTGAAAGAAAGAATTGTTGTAGTTTTTTTTCATTATTCTAAAACTCTTGTTGTTAGATACAAGATTTAATTAAGATCTAAG
CTCCTGCTTATTTAATGTAATTCTAAGGTACCATTTTAGAAAAAACATTTGTTTTAAGATTCCAAGAAACCTGTGAGTTAATACTATATT
TAAAAGAGAATTGGTAAATTTTGAATGTGTGTAATATTTTGGAACCTGTTTAAAAACCAAATATACCTGCAAATAGATACAGCCTATCCT

>4390_4390_1_ANK3-USP9Y_ANK3_chr10_61815416_ENST00000280772_USP9Y_chrY_14968265_ENST00000338981_length(amino acids)=4357AA_BP=
MAHAASQLKKNRDLEINAEEEPEKKRKHRKRSRDRKKKSDANASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVV
SELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVA
LQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDIT
PLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPV
DDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVS
QLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSA
REGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKN
GYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQG
AHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYIS
VVDTLKIVTEETMTTTTVTEKHKMNVPETMNEVLDMSDDEVRKANAPEMLSDGEYISDVEEGEDAMTGDTDKYLGPQDLKELGDDSLPAE
GYMGFSLGARSASLRSFSSDRSYTLNRSSYARDSMMIEELLVPSKEQHLTFTREFDSDSLRHYSWAADTLDNVNLVSSPIHSGFLVSFMV
DARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVL
RSENGETWKEHQFDSKNEDLTELLNGMDEELDSPEELGKKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGA
LTKRIRVGLQAQPVPDEIVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDTTPNLRLLCSITGGTSPAQWEDI
TGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLATQLYRELICVPYMAKFVVFAKMNDPVESSLRCFCMTDDKVDKTLEQQENFEE
VARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKTTKGLPQTAVCNLNITLPAHK
KETESDQDDEIEKTDRRQSFASLALRKRYSYLTEPGMIERSTGATRSLPTTYSYKPFFSTRPYQSWTTAPITVPGPAKSGFTSLSSSSSN
TPSASPLKSIWSVSTPSPIKSTLGASTTSSVKSISDVASPIRSFRTMSSPIKTVVSQSPYNIQVSSGTLARAPAVTEATPLKGLASNSTF
SSRTSPVTTAGSLLERSSITMTPPASPKSNINMYSSSLPFKSIITSAAPLISSPLKSVVSPVKSAVDVISSAKITMASSLSSPVKQMPGH
AEVALVNGSISPLKYPSSSTLINGCKATATLQEKISSATNSVSSVVSAATDTVEKVFSTTTAMPFSPLRSYVSAAPSAFQSLRTPSASAL
YTSLGSSISATTSSVTSSIITVPVYSVVNVLPEPALKKLPDSNSFTKSAAALLSPIKTLTTETHPQPHFSRTSSPVKSSLFLAPSALKLS
TPSSLSSSQEILKDVAEMKEDLMRMTAILQTDVPEEKPFQPELPKEGRIDDEEPFKIVEKVKEDLVKVSEILKKDVCVDNKGSPKSPKSD
KGHSPEDDWIEFSSEEIREARQQAAASQSPSLPERVQVKAKAASEKDYNLTKVIDYLTNDIGSSSLTNLKYKFEDAKKDGEERQKRVLKP
AIALQEHKLKMPPASMRTSTSEKELCKMADSFFGTDTILESPDDFSQHDQDKSPLSDSGFETRSEKTPSAPQSAESTGPKPLFHEVPIPP
VITETRTEVVHVIRSYDPSAGDVPQTQPEEPVSPKPSPTFMELEPKPTTSSIKEKVKAFQMKASSEEDDHNRVLSKGMRVKEETHITTTT
RMVYHSPPGGEGASERIEETMSVHDIMKAFQSGRDPSKELAGLFEHKSAVSPDVHKSAAETSAQHAEKDNQMKPKLERIIEVHIEKGNQA
EPTEVIIRETKKHPEKEMYVYQKDLSRGDINLKDFLPEKHDAFPCSEEQGQQEEEELTAEESLPSYLESSRVNTPVSQEEDSRPSSAQLI
SDDSYKTLKLLSQHSIEYHDDELSELRGESYRFAEKMLLSEKLDVSHSDTEESVTDHAGPPSSELQGSDKRSREKIATAPKKEILSKIYK
DVSENGVGKVSKDEHFDKVTVLHYSGNVSSPKHAMWMRFTEDRLDRGREKLIYEDRVDRTVKEAEEKLTEVSQFFRDKTEKLNDELQSPE
KKARPKNGKEYSSQSPTSSSPEKVLLTELLASNDEWVKARQHGPDGQGFPKAEEKAPSLPSSPEKMVLSQQTEDSKSTVEAKGSISQSKA
PDGPQSGFQLKQSKLSSIRLKFEQGTHAKSKDMSQEDRKSDGQSRIPVKKIQESKLPVYQVFAREKQQKAIDLPDESVSVQKDFMVLKTK
DEHAQSNEIVVNDSGSDNVKKQRTEMSSKAMPDSFSEQQAKDLACHITSDLATRGPWDKKVFRTWESSGATNNKSQKEKLSHVLVHDVRE
NHIGHPESKSVDQKNEFMSVTERERKLLTNGSLSEIKEMTVKSPSKKVLYREYVVKEGDHPGGLLDQPSRRSESSAVSHIPVRVADERRM
LSSNIPDGFCEQSAFPKHELSQKLSQSSMSKETVETQHFNSIEDEKVTYSEISKVSKHQSYVGLCPPLEETETSPTKSPDSLEFSPGKES
PSSDVFDHSPIDGLEKLAPLAQTEGGKEIKTLPVYVSFVQVGKQYEKEIQQGGVKKIISQECKTVQETRGTFYTTRQQKQPPSPQGSPED
DTLEQVSFLDSSGKSPLTPETPSSEEVSYEFTSKTPDSLIAYIPGKPSPIPEVSEESEEEEQAKSTSLKQTTVEETAVEREMPNDVSKDS
NQRPKNNRVAYIEFPPPPPLDADQIESDKKHHYLPEKEVDMIEVNLQDEHDKYQLAEPVIRVQPPSPVPPGADVSDSSDDESIYQPVPVK
KYTFKLKEVDDEQKEKPKASAEKASNQKELESNGSGKDNEFGLGLDSPQNEIAQNGNNDQSITECSIATTAEFSHDTDATEIDSLDGYDL
QDEDDGLTESDSKLPIQAMEIKKDIWNTEGILKPADRSFSQSKLEVIEEEGKVGPDEDKPPSKSSSSEKTPDKTDQKSGAQFFTLEGRHP
DRSVFPDTYFSYKVDEEFATPFKTVATKGLDFDPWSNNRGDDEVFDSKSREDETKPFGLAVEDRSPATTPDTTPARTPTDESTPTSEPNP
FPFHEGKMFEMTRSGAIDMSKRDFVEERLQFFQIGEHTSEGKSGDQGEGDKSMVTATPQPQSGDTTVETNLERNVETPTVEPNPSIPTSG
ECQEGTSSSGSLEKSAAATNTSKVDPKLRTPIKMGISASTMTMKKEGPGEITDKIEAVMTSCQGLENETITMISNTANSQMGVRPHEKHD
FQKDNFNNNNNLDSSTIQTDNIMSNIVLTEHSAPTCTTEKDNPVKVSSGKKTGVLQGHCVRDKQKVLGEQQKTKELIGIRQKSKLPIKAT
SPKDTFPPNHMSNTKASKMKQVSQSEKTKALTTSSCVDVKSRIPVKNTHRDNIIAVRKACATQKQGQPEKGKAKQLPSKLPVKVRSTCVT
TTTTTATTTTTTTTTTTTSCTVKVRKSQLKEVCKHSIEYFKGISGETLKLVDRLSEEEKKMQSELSDEEESTSRNTSLSETSRGGQPSVT
TKSARDKKTEAAPLKSKSEKAGSEKRSSRRTGPQSPCERTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKK
WVTRDGKNATTDALTSVLTKINRIDIVTLLEGPIFDYGNISGTRSFADENNVFHDPVDGWQNETSSGNLESCAQARRVTGGLLDRLDDSP
DQCRDSITSYLKGEAGKFEANGSHTEITPEAKTKSYFPESQNDVGKQSTKETLKPKIHGSGHVEEPASPLAAYQKSLEETSKLIIEETKP

--------------------------------------------------------------
>4390_4390_2_ANK3-USP9Y_ANK3_chr10_61815416_ENST00000355288_USP9Y_chrY_14968265_ENST00000338981_length(transcript)=5613nt_BP=3586nt
AGCTGAGAACAAAGTTGAAAGTTTGCCTGGAGCTCCATGCCACTCCCCGCCTGGGCCACTGCTTTGTTTTCTTCTAATGTTTTTCCTCTA
CCTGGGTTGGCTGTTTCTTCATTCATATTTGAGAAGAATCACCTCCTAATTAAATGTAGCACTTCGCTCTCTCCCTACATGAAGGCTGTC
TTGGTTACCCGACTAGGCAACGCGCATTGGTATCAAATTACCGAAAGTCTACACCGGAGCAGTCCTCATATTTACATACAAATAACTCAG
GGGCTTGCATTTATGTCACCATTCTGTCCTGCTAGAGGCTTGCCAGAGGAGTTTTTAATCCAATCAGAAGGAGCTTTAAAAGGATGTCTG
CGAAGTGGTCAAAAGGATCTTAACCTCAATTAAGTGGGGTTTTTTAAAAAGATTTTTTTGGGGGCCTGAAATTTTGAAAATCTTCGAACT
CTGAGTGGGGAAAGATGTATAATTCCTCAATTGCCTACGAGGATATCAAGATGCTGAGAGGAATTCAGCGGTGGTGAAGAGAGTGGATAC
AAACCAGGGATTGGTTTCCTTGAGCTGTTTTGGAGGTTGATTCTAAATCACTGCTTAAGGAATTCCTGGAAACATCAGGAAAACATTTGA
TCATCCAAGCCTAGTGGAAATGGCTTTACCGCAGAGTGAAGATGCAATGACCGGGGACACAGACAAATATCTTGGGCCACAGGACCTTAA
GGAATTGGGTGATGATTCCCTGCCTGCAGAGGGTTACATGGGCTTTAGTCTCGGAGCGCGTTCTGCCAGCCTCCGCTCCTTCAGTTCGGA
TAGGTCTTACACCTTGAACAGAAGCTCCTATGCACGGGACAGCATGATGATTGAAGAACTCCTTGTGCCATCCAAAGAGCAGCATCTAAC
ATTCACAAGGGAATTTGATTCAGATTCTCTTAGACATTACAGCTGGGCTGCAGACACCTTAGACAATGTCAATCTTGTTTCAAGCCCCAT
TCATTCTGGGTTTCTGGTTAGCTTTATGGTGGACGCGAGAGGGGGCTCCATGAGAGGAAGCCGTCATCACGGGATGAGAATCATCATTCC
TCCACGCAAGTGTACGGCCCCCACTCGAATCACCTGCCGTTTGGTAAAGAGACATAAACTGGCCAACCCACCCCCCATGGTGGAAGGAGA
GGGATTAGCCAGTAGGCTGGTAGAAATGGGTCCTGCAGGGGCACAATTTTTAGGCCCTGTCATAGTGGAAATCCCTCACTTTGGGTCCAT
GAGAGGAAAAGAGAGAGAACTCATTGTTCTTCGAAGTGAAAATGGTGAAACTTGGAAGGAGCATCAGTTTGACAGCAAAAATGAAGATTT
AACCGAGTTACTTAATGGCATGGATGAAGAACTTGATAGCCCAGAAGAGTTAGGGAAAAAGCGTATCTGCAGGATTATCACGAAAGATTT
CCCCCAGTATTTTGCAGTGGTTTCCCGGATTAAGCAGGAAAGCAACCAGATTGGTCCTGAAGGTGGAATTCTGAGCAGCACCACAGTGCC
CCTTGTTCAAGCATCTTTCCCAGAGGGTGCCCTAACTAAAAGAATTCGAGTGGGCCTCCAGGCCCAGCCTGTTCCAGATGAAATTGTGAA
AAAGATCCTTGGAAACAAAGCAACTTTTAGCCCAATTGTCACTGTGGAACCAAGAAGACGGAAATTCCATAAACCAATCACAATGACCAT
TCCGGTGCCCCCGCCCTCAGGAGAAGGTGTATCCAATGGATACAAAGGGGACACTACACCCAATCTGCGTCTTCTCTGTAGCATTACAGG
GGGCACTTCGCCTGCTCAGTGGGAAGACATCACAGGAACAACTCCTTTGACGTTTATAAAAGATTGTGTCTCCTTTACAACCAATGTTTC
AGCCAGATTTTGGCTTGCAGACTGCCATCAAGTTTTAGAAACTGTGGGGTTAGCCACGCAACTGTACAGAGAATTGATATGTGTTCCATA
TATGGCCAAGTTTGTTGTTTTTGCCAAAATGAATGATCCCGTAGAATCTTCCTTGCGATGTTTCTGCATGACAGATGACAAAGTGGACAA
AACTTTAGAGCAACAAGAGAATTTTGAGGAAGTCGCAAGAAGCAAAGATATTGAGGTTCTGGAAGGAAAACCTATTTATGTTGATTGTTA
TGGAAATTTGGCCCCACTTACCAAAGGAGGACAGCAACTTGTTTTTAACTTTTATTCTTTCAAAGAAAATAGACTGCCATTTTCCATCAA
GATTAGAGACACCAGCCAAGAGCCCTGTGGTCGTCTGTCTTTTCTGAAAGAACCAAAGACAACAAAAGGACTGCCTCAAACAGCGGTTTG
CAACTTAAATATCACTCTGCCAGCACATAAAAAGATTGAGAAAACAGATAGACGACAGAGCTTCGCATCCTTAGCTTTACGTAAGCGCTA
CAGCTACTTGACTGAGCCTGGAATGAGTCCACAGAGTCCATGTGAACGGACAGATATCAGGATGGCAATAGTAGCCGATCACCTGGGACT
TAGTTGGACAGAACTGGCAAGGGAACTGAATTTTTCAGTGGATGAAATCAATCAAATACGTGTGGAAAATCCAAATTCTTTAATTTCTCA
GAGCTTCATGTTATTAAAAAAATGGGTTACCAGAGACGGAAAAAATGCCACAACTGATGCCTTAACTTCGGTCTTGACAAAAATTAATCG
AATAGATATAGTGACACTGCTAGAAGGACCAATATTTGATTATGGAAATATTTCAGGCACCAGAAGTTTTGCAGATGAGAACAATGTTTT
CCATGACCCTGTTGATGGTTATCCTTCCCTTCAAGTGGAACTGGAAACCCCCACAGGGTTGCACTACACACCACCTACCCCTTTCCAGCA
AGATGATTATTTTAGTGATATCTCTAGCATAGAATCTCCCCTTAGAACCCCTAGTAGACTGAGTGATGGGCTAGTGCCTTCCCAGGGGAA
CATAGAGCATTCCGCAGATGGACCTCCAGTCGTAACTGCAGAAGACGCTTCCTTAGAAGACAGCAAACTGGAAGACTCAGTGCCTTTAAC
AGAAATGCCTGAAGCAGTGGATGTAGATGAGAGCCAGTTGGAGAATGTATGTCTGAGTTGGCAGAATGAGACATCAAGTGGAAACCTAGA
GTCCTGCGCTCAAGCTCGAAGAGTAACTGGTGGGTTACTAGATCGACTGGATGACAGCCCTGACCAGTGTAGAGATTCCATTACCTCATA
TCTCAAAGGAGAAGCTGGCAAATTTGAAGCAAATGGAAGCCATACAGAAATCACTCCAGAAGCAAAGACAAAATCTTACTTTCCAGAATC
CCAAAATGATGTAGGAAAACAGAGTACCAAGGAAACTCTGAAACCAAAAATACATGGATCTGGTCATGTTGAAGAACCAGCATCACCACT
AGCAGCATATCAGAAATCTCTAGAAGAAACCAGCAAGCTTATAATAGAAGAGACTAAACCCTGTGTGCCTGTCAGTATGAAAAAGATGAG
TAGGACTTCTCCAGCAGATGGCAAGCCAAGGCTTAGCCTCCATGAAGAAGAGGGGTCCAGTGGGTCTGAGCAAAAGAATTCATAATGCAC
TTAAAGGAATTCCAGATGACAGAGATGGGCTGTTCGATACAATACAGCGCTCGAAGAATCACTATCAAAAACGAGCATATCAGTGCATAA
AATGTATGGTAGCTCTATTTAGCAGTTGTCCTGTTGCTTACCAGATCTTACAGGGTAACGGAGATCTTAAAAGAAAATGGACCTGGGCAG
TGGAATGGCTAGGAGATGAACTTGAAAGAAGACCATATACTGGCAATCCTCAGTATAGTTACAACAATTGGTCTCCTCCAGTACAAAGCA
ATGAAACAGCAAATGGTTATTTCTTAGAAAGATCACATAGTGCTAGGATGACACTTGCAAAAGCTTGTGAACTCTGTCCAGAAGAGGAGC
CAGATGACCAGGATGCCCCAGATGAGCATGAGCCCTCTCCATCAGAAGATGCCCCATTATATCCTCATTCACCTGCCTCTCAGTATCAAC
AGAATAATCATGTACATGGACAGCCATATACAGGACCAGCAGCACATCACTTGAACAACCCTCAGAAAACAGGCCAACGAACACAAGAAA
ATTATGAAGGCAATGAAGAAGTATCCTCACCTCAGATGAAGGATCAGTGAAAAGCAATAATTAACTGCTTCCTTTATGACTATGCACTAA
GGTCTTATAGTCCAAACTTTCTCTGTGTCTGGCTAGTATTGAAAACTAGATAAACTGCTCCAAACCAACATGGAGTAAAGAGCATATTCA
CTGGTTTATTTGCAGTAATTTGCAATTTGTCAGTGTATAAGACACATGCAGGGTGAAGTGTACAGAGTTTTGTAACAAATGACTGGTCCT
AATCTGTAAATGAGAAAGGTATATATACTATGTTAATGTCTGACTGTTAATTCTTAAGCAAGAAACTTTTTTTGATGAAAACAAGTCAGA
TCTACACAGTCACACAATTATTTTTTGTTGTGTTCACTACATTGTGCAATTGATATTGCCTGCTTTGAGCAGTTTGGTCAACTTACCAAC
TTCCCCCCAAAAAAGGGAACATAAAAGAGCCCATCTTTGTCAGTTTACACCAATAGTTTCTTGTTAATCCTTCTTTCCTGGATATATAAG
GCTGGTGGTAACTTTTGAATTATATGGTTGATGTGGAAAATTGGCAGTGTAACATTTCTAGATACTTTTCATTACCTTTTTATTCTGGTA
TATAGGCTAACCACTTTAAAGCTATTCTTATGCTGTAACAGTTAGCATGGCTTCACACTGTTTGTGTAGCCAAGAGGACAGAATTACATG
AATGACAGTGCCCAGAGTGACAGCTGTATATTGCTCAGAGCTTTTATTTCTTATACCTAGAATAAATATAAAATGGGGGAAAAATGTGAC
AGACAAGCAGTTTTTCATTGCACACATATTCTTCACATTTAATGTTTGATAGTTCAATTTCTTGAGCTGAAGAATATCAAAGTATCGATA
ATACGAATTTTAAAATATTAAAACCAATACACAAAATTTTCCTATGTCAGAATGTGGTGGAGCATAATAGATTGTATTTGGTGTGCTTGC
GATTTTTTTTTTCCATAGAATTTATTAAGTGAAGTTTCTAAAACTTTGCTTCTCCTGATCCCGGTGAAGTGTACATCATAAGAATCCATA
GTACTTTGAAGTACCATTGCACCAAGATGTCTGACTGAATTCATAGTCACACTTTTATTTGAAAGAAAGAATTGTTGTAGTTTTTTTTCA
TTATTCTAAAACTCTTGTTGTTAGATACAAGATTTAATTAAGATCTAAGCTCCTGCTTATTTAATGTAATTCTAAGGTACCATTTTAGAA
AAAACATTTGTTTTAAGATTCCAAGAAACCTGTGAGTTAATACTATATTTAAAAGAGAATTGGTAAATTTTGAATGTGTGTAATATTTTG
GAACCTGTTTAAAAACCAAATATACCTGCAAATAGATACAGCCTATCCTATACTATTTAAATGTTTGGCTGTTTTGTTTTATAGAAATTA

>4390_4390_2_ANK3-USP9Y_ANK3_chr10_61815416_ENST00000355288_USP9Y_chrY_14968265_ENST00000338981_length(amino acids)=981AA_BP=
MALPQSEDAMTGDTDKYLGPQDLKELGDDSLPAEGYMGFSLGARSASLRSFSSDRSYTLNRSSYARDSMMIEELLVPSKEQHLTFTREFD
SDSLRHYSWAADTLDNVNLVSSPIHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRL
VEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLTELLNGMDEELDSPEELGKKRICRIITKDFPQYFAV
VSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPDEIVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPS
GEGVSNGYKGDTTPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLATQLYRELICVPYMAKFVV
FAKMNDPVESSLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRDTSQ
EPCGRLSFLKEPKTTKGLPQTAVCNLNITLPAHKKIEKTDRRQSFASLALRKRYSYLTEPGMSPQSPCERTDIRMAIVADHLGLSWTELA
RELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDGKNATTDALTSVLTKINRIDIVTLLEGPIFDYGNISGTRSFADENNVFHDPVDG
YPSLQVELETPTGLHYTPPTPFQQDDYFSDISSIESPLRTPSRLSDGLVPSQGNIEHSADGPPVVTAEDASLEDSKLEDSVPLTEMPEAV
DVDESQLENVCLSWQNETSSGNLESCAQARRVTGGLLDRLDDSPDQCRDSITSYLKGEAGKFEANGSHTEITPEAKTKSYFPESQNDVGK

--------------------------------------------------------------
>4390_4390_3_ANK3-USP9Y_ANK3_chr10_61815416_ENST00000373827_USP9Y_chrY_14968265_ENST00000338981_length(transcript)=7715nt_BP=5688nt
ACAGCAGGAGGAGGATAGGCCGCGCTGGGCGGGCGTCGCGGGGCCGCGCTTGGTGTTCCTGAGCCGCGGCCGAACTTTTTCCCAAGAAGT
CCCACGTTTGGAGGCCCGAGGAGCGGGACGGGGAGGAGAGACTGGAGTTCCTGGAAGGAGCAGCAGCAGCAGCCCCACAACATGGCCTCC
TCCGCCTCCTCCTCTCCCGCGGGCACCGAGGACTCCGCTCCTGCCCAGGGTGGCTTTGGATCAGATTATTCACGAAGCTCTAGAAAGTCT
GATGCCAATGCAAGTTACTTAAGAGCAGCTCGAGCTGGACACCTTGAAAAGGCCCTCGACTACATAAAAAATGGAGTTGACATCAACATT
TGCAATCAGAATGGGTTGAACGCTCTCCACCTTGCTTCCAAAGAAGGCCATGTAGAGGTTGTTTCTGAGCTGCTGCAGAGAGAAGCCAAT
GTGGATGCAGCTACAAAGAAAGGAAACACAGCATTGCACATCGCATCTTTGGCTGGGCAAGCAGAGGTGGTAAAAGTCTTGGTTACAAAT
GGAGCCAATGTCAATGCACAATCTCAGAATGGTTTCACGCCATTGTATATGGCAGCCCAGGAAAATCACCTGGAAGTTGTCAAGTTTCTT
CTTGACAATGGTGCAAGCCAGAGCCTAGCCACAGAGGATGGCTTCACACCATTGGCAGTGGCTTTGCAACAAGGTCACGACCAAGTCGTT
TCGCTCCTGCTAGAGAATGACACCAAAGGAAAAGTGCGTCTCCCAGCTCTTCATATCGCGGCCCGAAAAGACGACACGAAAGCCGCCGCC
CTGCTGCTGCAGAATGACAACAATGCAGATGTGGAATCAAAGAGTGGCTTCACTCCGCTCCACATAGCTGCTCACTATGGAAATATCAAT
GTAGCCACGTTGCTGTTAAACCGAGCGGCTGCTGTGGATTTCACCGCAAGGAATGACATCACTCCTTTACATGTTGCATCAAAAAGAGGA
AATGCAAATATGGTAAAACTATTGCTCGATCGAGGAGCTAAAATCGATGCCAAAACCAGGGATGGTCTGACACCACTGCACTGTGGAGCA
AGGAGTGGCCACGAGCAGGTGGTAGAAATGTTGCTTGATCGAGCTGCCCCCATTCTTTCAAAAACCAAGAATGGATTATCTCCATTGCAC
ATGGCCACACAAGGGGATCATTTAAACTGCGTCCAGCTTCTCCTCCAGCATAATGTACCCGTGGATGATGTCACCAATGACTACCTGACT
GCCCTACACGTGGCTGCCCACTGTGGCCATTACAAAGTTGCCAAGGTTCTCTTGGATAAGAAAGCTAACCCCAATGCCAAAGCCCTGAAT
GGCTTTACCCCTCTTCATATTGCCTGCAAGAAGAATCGAATTAAAGTAATGGAACTCCTTCTGAAACACGGTGCATCCATCCAAGCTGTA
ACCGAGTCGGGCCTTACCCCAATCCATGTTGCTGCCTTCATGGGGCATGTAAATATTGTATCACAACTAATGCATCATGGAGCCTCACCA
AACACCACCAATGTGAGAGGAGAAACAGCACTGCACATGGCAGCTCGCTCCGGCCAAGCTGAAGTTGTGCGGTATCTGGTACAAGACGGA
GCTCAGGTAGAAGCTAAAGCTAAGGATGACCAAACACCACTCCACATTTCAGCCCGACTGGGGAAAGCAGACATAGTACAACAGCTGTTG
CAGCAAGGGGCATCTCCAAATGCAGCCACAACTTCTGGGTACACCCCACTTCACCTTTCCGCCCGAGAGGGGCATGAGGATGTGGCCGCG
TTCCTTTTGGATCATGGAGCGTCTTTATCTATAACAACAAAGAAAGGATTTACTCCTCTTCATGTGGCAGCAAAATATGGAAAGCTTGAA
GTCGCCAATCTCCTGCTACAGAAAAGTGCATCTCCAGATGCTGCTGGGAAGAGCGGGCTAACACCACTGCATGTAGCTGCACATTACGAT
AATCAGAAAGTGGCCCTTCTGCTTTTGGACCAAGGAGCCTCACCTCACGCAGCCGCAAAGAATGGTTATACGCCACTGCACATCGCTGCC
AAAAAGAACCAGATGGACATAGCGACAACTCTGCTGGAATATGGTGCTGATGCCAACGCAGTTACCCGGCAAGGAATTGCTTCCGTCCAT
CTCGCAGCTCAGGAAGGGCACGTGGACATGGTGTCGCTGCTCCTCGGTAGAAATGCGAATGTGAACCTGAGCAATAAGAGCGGCCTGACC
CCACTCCATTTGGCTGCTCAAGAAGATCGAGTGAATGTGGCAGAAGTCCTCGTAAACCAAGGGGCTCATGTGGACGCCCAGACAAAGATG
GGATACACACCACTGCATGTGGGCTGCCACTATGGAAATATCAAGATTGTTAATTTCCTGCTCCAGCATTCTGCAAAAGTTAATGCCAAA
ACAAAGAATGGGTATACGCCATTACATCAAGCAGCACAGCAGGGGCATACGCATATAATAAATGTCTTACTTCAGAACAACGCCTCCCCC
AATGAACTCACTGTGAATGGGAATACTGCCCTTGGCATTGCCCGGCGCCTCGGCTACATCTCAGTAGTGGACACCCTGAAGATAGTGACC
GAAGAGACCATGACCACAACTACTGTCACAGAGAAGCACAAAATGAATGTTCCAGAAACGATGAATGAAGTTCTTGATATGTCTGATGAT
GAAGTTCGTAAAGCCAATGCCCCTGAAATGCTCAGTGATGGCGAATATATCTCAGATGTTGAAGAAGGTGAAGATGCAATGACCGGGGAC
ACAGACAAATATCTTGGGCCACAGGACCTTAAGGAATTGGGTGATGATTCCCTGCCTGCAGAGGGTTACATGGGCTTTAGTCTCGGAGCG
CGTTCTGCCAGCCTCCGCTCCTTCAGTTCGGATAGGTCTTACACCTTGAACAGAAGCTCCTATGCACGGGACAGCATGATGATTGAAGAA
CTCCTTGTGCCATCCAAAGAGCAGCATCTAACATTCACAAGGGAATTTGATTCAGATTCTCTTAGACATTACAGCTGGGCTGCAGACACC
TTAGACAATGTCAATCTTGTTTCAAGCCCCATTCATTCTGGGTTTCTGGTTAGCTTTATGGTGGACGCGAGAGGGGGCTCCATGAGAGGA
AGCCGTCATCACGGGATGAGAATCATCATTCCTCCACGCAAGTGTACGGCCCCCACTCGAATCACCTGCCGTTTGGTAAAGAGACATAAA
CTGGCCAACCCACCCCCCATGGTGGAAGGAGAGGGATTAGCCAGTAGGCTGGTAGAAATGGGTCCTGCAGGGGCACAATTTTTAGGCCCT
GTCATAGTGGAAATCCCTCACTTTGGGTCCATGAGAGGAAAAGAGAGAGAACTCATTGTTCTTCGAAGTGAAAATGGTGAAACTTGGAAG
GAGCATCAGTTTGACAGCAAAAATGAAGATTTAACCGAGTTACTTAATGGCATGGATGAAGAACTTGATAGCCCAGAAGAGTTAGGGAAA
AAGCGTATCTGCAGGATTATCACGAAAGATTTCCCCCAGTATTTTGCAGTGGTTTCCCGGATTAAGCAGGAAAGCAACCAGATTGGTCCT
GAAGGTGGAATTCTGAGCAGCACCACAGTGCCCCTTGTTCAAGCATCTTTCCCAGAGGGTGCCCTAACTAAAAGAATTCGAGTGGGCCTC
CAGGCCCAGCCTGTTCCAGATGAAATTGTGAAAAAGATCCTTGGAAACAAAGCAACTTTTAGCCCAATTGTCACTGTGGAACCAAGAAGA
CGGAAATTCCATAAACCAATCACAATGACCATTCCGGTGCCCCCGCCCTCAGGAGAAGGTGTATCCAATGGATACAAAGGGGACACTACA
CCCAATCTGCGTCTTCTCTGTAGCATTACAGGGGGCACTTCGCCTGCTCAGTGGGAAGACATCACAGGAACAACTCCTTTGACGTTTATA
AAAGATTGTGTCTCCTTTACAACCAATGTTTCAGCCAGATTTTGGCTTGCAGACTGCCATCAAGTTTTAGAAACTGTGGGGTTAGCCACG
CAACTGTACAGAGAATTGATATGTGTTCCATATATGGCCAAGTTTGTTGTTTTTGCCAAAATGAATGATCCCGTAGAATCTTCCTTGCGA
TGTTTCTGCATGACAGATGACAAAGTGGACAAAACTTTAGAGCAACAAGAGAATTTTGAGGAAGTCGCAAGAAGCAAAGATATTGAGGTT
CTGGAAGGAAAACCTATTTATGTTGATTGTTATGGAAATTTGGCCCCACTTACCAAAGGAGGACAGCAACTTGTTTTTAACTTTTATTCT
TTCAAAGAAAATAGACTGCCATTTTCCATCAAGATTAGAGACACCAGCCAAGAGCCCTGTGGTCGTCTGTCTTTTCTGAAAGAACCAAAG
ACAACAAAAGGACTGCCTCAAACAGCGGTTTGCAACTTAAATATCACTCTGCCAGCACATAAAAAGATTGAGAAAACAGATAGACGACAG
AGCTTCGCATCCTTAGCTTTACGTAAGCGCTACAGCTACTTGACTGAGCCTGGAATGAGTCCACAGAGTCCATGTGAACGGACAGATATC
AGGATGGCAATAGTAGCCGATCACCTGGGACTTAGTTGGACAGAACTGGCAAGGGAACTGAATTTTTCAGTGGATGAAATCAATCAAATA
CGTGTGGAAAATCCAAATTCTTTAATTTCTCAGAGCTTCATGTTATTAAAAAAATGGGTTACCAGAGACGGAAAAAATGCCACAACTGAT
GCCTTAACTTCGGTCTTGACAAAAATTAATCGAATAGATATAGTGACACTGCTAGAAGGACCAATATTTGATTATGGAAATATTTCAGGC
ACCAGAAGTTTTGCAGATGAGAACAATGTTTTCCATGACCCTGTTGATGGTTATCCTTCCCTTCAAGTGGAACTGGAAACCCCCACAGGG
TTGCACTACACACCACCTACCCCTTTCCAGCAAGATGATTATTTTAGTGATATCTCTAGCATAGAATCTCCCCTTAGAACCCCTAGTAGA
CTGAGTGATGGGCTAGTGCCTTCCCAGGGGAACATAGAGCATTCCGCAGATGGACCTCCAGTCGTAACTGCAGAAGACGCTTCCTTAGAA
GACAGCAAACTGGAAGACTCAGTGCCTTTAACAGAAATGCCTGAAGCAGTGGATGTAGATGAGAGCCAGTTGGAGAATGTATGTCTGAGT
TGGCAGAATGAGACATCAAGTGGAAACCTAGAGTCCTGCGCTCAAGCTCGAAGAGTAACTGGTGGGTTACTAGATCGACTGGATGACAGC
CCTGACCAGTGTAGAGATTCCATTACCTCATATCTCAAAGGAGAAGCTGGCAAATTTGAAGCAAATGGAAGCCATACAGAAATCACTCCA
GAAGCAAAGACAAAATCTTACTTTCCAGAATCCCAAAATGATGTAGGAAAACAGAGTACCAAGGAAACTCTGAAACCAAAAATACATGGA
TCTGGTCATGTTGAAGAACCAGCATCACCACTAGCAGCATATCAGAAATCTCTAGAAGAAACCAGCAAGCTTATAATAGAAGAGACTAAA
CCCTGTGTGCCTGTCAGTATGAAAAAGATGAGTAGGACTTCTCCAGCAGATGGCAAGCCAAGGCTTAGCCTCCATGAAGAAGAGGGGTCC
AGTGGGTCTGAGCAAAAGAATTCATAATGCACTTAAAGGAATTCCAGATGACAGAGATGGGCTGTTCGATACAATACAGCGCTCGAAGAA
TCACTATCAAAAACGAGCATATCAGTGCATAAAATGTATGGTAGCTCTATTTAGCAGTTGTCCTGTTGCTTACCAGATCTTACAGGGTAA
CGGAGATCTTAAAAGAAAATGGACCTGGGCAGTGGAATGGCTAGGAGATGAACTTGAAAGAAGACCATATACTGGCAATCCTCAGTATAG
TTACAACAATTGGTCTCCTCCAGTACAAAGCAATGAAACAGCAAATGGTTATTTCTTAGAAAGATCACATAGTGCTAGGATGACACTTGC
AAAAGCTTGTGAACTCTGTCCAGAAGAGGAGCCAGATGACCAGGATGCCCCAGATGAGCATGAGCCCTCTCCATCAGAAGATGCCCCATT
ATATCCTCATTCACCTGCCTCTCAGTATCAACAGAATAATCATGTACATGGACAGCCATATACAGGACCAGCAGCACATCACTTGAACAA
CCCTCAGAAAACAGGCCAACGAACACAAGAAAATTATGAAGGCAATGAAGAAGTATCCTCACCTCAGATGAAGGATCAGTGAAAAGCAAT
AATTAACTGCTTCCTTTATGACTATGCACTAAGGTCTTATAGTCCAAACTTTCTCTGTGTCTGGCTAGTATTGAAAACTAGATAAACTGC
TCCAAACCAACATGGAGTAAAGAGCATATTCACTGGTTTATTTGCAGTAATTTGCAATTTGTCAGTGTATAAGACACATGCAGGGTGAAG
TGTACAGAGTTTTGTAACAAATGACTGGTCCTAATCTGTAAATGAGAAAGGTATATATACTATGTTAATGTCTGACTGTTAATTCTTAAG
CAAGAAACTTTTTTTGATGAAAACAAGTCAGATCTACACAGTCACACAATTATTTTTTGTTGTGTTCACTACATTGTGCAATTGATATTG
CCTGCTTTGAGCAGTTTGGTCAACTTACCAACTTCCCCCCAAAAAAGGGAACATAAAAGAGCCCATCTTTGTCAGTTTACACCAATAGTT
TCTTGTTAATCCTTCTTTCCTGGATATATAAGGCTGGTGGTAACTTTTGAATTATATGGTTGATGTGGAAAATTGGCAGTGTAACATTTC
TAGATACTTTTCATTACCTTTTTATTCTGGTATATAGGCTAACCACTTTAAAGCTATTCTTATGCTGTAACAGTTAGCATGGCTTCACAC
TGTTTGTGTAGCCAAGAGGACAGAATTACATGAATGACAGTGCCCAGAGTGACAGCTGTATATTGCTCAGAGCTTTTATTTCTTATACCT
AGAATAAATATAAAATGGGGGAAAAATGTGACAGACAAGCAGTTTTTCATTGCACACATATTCTTCACATTTAATGTTTGATAGTTCAAT
TTCTTGAGCTGAAGAATATCAAAGTATCGATAATACGAATTTTAAAATATTAAAACCAATACACAAAATTTTCCTATGTCAGAATGTGGT
GGAGCATAATAGATTGTATTTGGTGTGCTTGCGATTTTTTTTTTCCATAGAATTTATTAAGTGAAGTTTCTAAAACTTTGCTTCTCCTGA
TCCCGGTGAAGTGTACATCATAAGAATCCATAGTACTTTGAAGTACCATTGCACCAAGATGTCTGACTGAATTCATAGTCACACTTTTAT
TTGAAAGAAAGAATTGTTGTAGTTTTTTTTCATTATTCTAAAACTCTTGTTGTTAGATACAAGATTTAATTAAGATCTAAGCTCCTGCTT
ATTTAATGTAATTCTAAGGTACCATTTTAGAAAAAACATTTGTTTTAAGATTCCAAGAAACCTGTGAGTTAATACTATATTTAAAAGAGA
ATTGGTAAATTTTGAATGTGTGTAATATTTTGGAACCTGTTTAAAAACCAAATATACCTGCAAATAGATACAGCCTATCCTATACTATTT

>4390_4390_3_ANK3-USP9Y_ANK3_chr10_61815416_ENST00000373827_USP9Y_chrY_14968265_ENST00000338981_length(amino acids)=1890AA_BP=
MGGRRGAALGVPEPRPNFFPRSPTFGGPRSGTGRRDWSSWKEQQQQPHNMASSASSSPAGTEDSAPAQGGFGSDYSRSSRKSDANASYLR
AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQS
QNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNN
ADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVV
EMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIA
CKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAK
DDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQK
SASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHV
DMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPL
HQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTLKIVTEETMTTTTVTEKHKMNVPETMNEVLDMSDDEVRKANAP
EMLSDGEYISDVEEGEDAMTGDTDKYLGPQDLKELGDDSLPAEGYMGFSLGARSASLRSFSSDRSYTLNRSSYARDSMMIEELLVPSKEQ
HLTFTREFDSDSLRHYSWAADTLDNVNLVSSPIHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMV
EGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLTELLNGMDEELDSPEELGKKRICRIIT
KDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPDEIVKKILGNKATFSPIVTVEPRRRKFHKPIT
MTIPVPPPSGEGVSNGYKGDTTPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLATQLYRELIC
VPYMAKFVVFAKMNDPVESSLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPF
SIKIRDTSQEPCGRLSFLKEPKTTKGLPQTAVCNLNITLPAHKKIEKTDRRQSFASLALRKRYSYLTEPGMSPQSPCERTDIRMAIVADH
LGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDGKNATTDALTSVLTKINRIDIVTLLEGPIFDYGNISGTRSFADEN
NVFHDPVDGYPSLQVELETPTGLHYTPPTPFQQDDYFSDISSIESPLRTPSRLSDGLVPSQGNIEHSADGPPVVTAEDASLEDSKLEDSV
PLTEMPEAVDVDESQLENVCLSWQNETSSGNLESCAQARRVTGGLLDRLDDSPDQCRDSITSYLKGEAGKFEANGSHTEITPEAKTKSYF
PESQNDVGKQSTKETLKPKIHGSGHVEEPASPLAAYQKSLEETSKLIIEETKPCVPVSMKKMSRTSPADGKPRLSLHEEEGSSGSEQKNS

--------------------------------------------------------------
>4390_4390_4_ANK3-USP9Y_ANK3_chr10_61815416_ENST00000503366_USP9Y_chrY_14968265_ENST00000338981_length(transcript)=7701nt_BP=5674nt
AAGCAGCGGCTGCTTTGCCTGGGGAGCACCCGTAAATGGACTTTGGTCTCAATGCTTTGACTCTTTGCCGTGGTTTTGGATGTTGGAATA
CCGGCGGTGATCTGTCTTTTATAAACTCACCTGATTTAAAGGAAAGATGAGTGAAGAACCAAAGGAGAAAAATGCAAAACCTGCTCATAG
GAAAAGGAAAGGAAAAAAGTCTGATGCCAATGCAAGTTACTTAAGAGCAGCTCGAGCTGGACACCTTGAAAAGGCCCTCGACTACATAAA
AAATGGAGTTGACATCAACATTTGCAATCAGAATGGGTTGAACGCTCTCCACCTTGCTTCCAAAGAAGGCCATGTAGAGGTTGTTTCTGA
GCTGCTGCAGAGAGAAGCCAATGTGGATGCAGCTACAAAGAAAGGAAACACAGCATTGCACATCGCATCTTTGGCTGGGCAAGCAGAGGT
GGTAAAAGTCTTGGTTACAAATGGAGCCAATGTCAATGCACAATCTCAGAATGGTTTCACGCCATTGTATATGGCAGCCCAGGAAAATCA
CCTGGAAGTTGTCAAGTTTCTTCTTGACAATGGTGCAAGCCAGAGCCTAGCCACAGAGGATGGCTTCACACCATTGGCAGTGGCTTTGCA
ACAAGGTCACGACCAAGTCGTTTCGCTCCTGCTAGAGAATGACACCAAAGGAAAAGTGCGTCTCCCAGCTCTTCATATCGCGGCCCGAAA
AGACGACACGAAAGCCGCCGCCCTGCTGCTGCAGAATGACAACAATGCAGATGTGGAATCAAAGAGTGGCTTCACTCCGCTCCACATAGC
TGCTCACTATGGAAATATCAATGTAGCCACGTTGCTGTTAAACCGAGCGGCTGCTGTGGATTTCACCGCAAGGAATGACATCACTCCTTT
ACATGTTGCATCAAAAAGAGGAAATGCAAATATGGTAAAACTATTGCTCGATCGAGGAGCTAAAATCGATGCCAAAACCAGGGATGGTCT
GACACCACTGCACTGTGGAGCAAGGAGTGGCCACGAGCAGGTGGTAGAAATGTTGCTTGATCGAGCTGCCCCCATTCTTTCAAAAACCAA
GAATGGATTATCTCCATTGCACATGGCCACACAAGGGGATCATTTAAACTGCGTCCAGCTTCTCCTCCAGCATAATGTACCCGTGGATGA
TGTCACCAATGACTACCTGACTGCCCTACACGTGGCTGCCCACTGTGGCCATTACAAAGTTGCCAAGGTTCTCTTGGATAAGAAAGCTAA
CCCCAATGCCAAAGCCCTGAATGGCTTTACCCCTCTTCATATTGCCTGCAAGAAGAATCGAATTAAAGTAATGGAACTCCTTCTGAAACA
CGGTGCATCCATCCAAGCTGTAACCGAGTCGGGCCTTACCCCAATCCATGTTGCTGCCTTCATGGGGCATGTAAATATTGTATCACAACT
AATGCATCATGGAGCCTCACCAAACACCACCAATGTGAGAGGAGAAACAGCACTGCACATGGCAGCTCGCTCCGGCCAAGCTGAAGTTGT
GCGGTATCTGGTACAAGACGGAGCTCAGGTAGAAGCTAAAGCTAAGGATGACCAAACACCACTCCACATTTCAGCCCGACTGGGGAAAGC
AGACATAGTACAACAGCTGTTGCAGCAAGGGGCATCTCCAAATGCAGCCACAACTTCTGGGTACACCCCACTTCACCTTTCCGCCCGAGA
GGGGCATGAGGATGTGGCCGCGTTCCTTTTGGATCATGGAGCGTCTTTATCTATAACAACAAAGAAAGGATTTACTCCTCTTCATGTGGC
AGCAAAATATGGAAAGCTTGAAGTCGCCAATCTCCTGCTACAGAAAAGTGCATCTCCAGATGCTGCTGGGAAGAGCGGGCTAACACCACT
GCATGTAGCTGCACATTACGATAATCAGAAAGTGGCCCTTCTGCTTTTGGACCAAGGAGCCTCACCTCACGCAGCCGCAAAGAATGGTTA
TACGCCACTGCACATCGCTGCCAAAAAGAACCAGATGGACATAGCGACAACTCTGCTGGAATATGGTGCTGATGCCAACGCAGTTACCCG
GCAAGGAATTGCTTCCGTCCATCTCGCAGCTCAGGAAGGGCACGTGGACATGGTGTCGCTGCTCCTCGGTAGAAATGCGAATGTGAACCT
GAGCAATAAGAGCGGCCTGACCCCACTCCATTTGGCTGCTCAAGAAGATCGAGTGAATGTGGCAGAAGTCCTCGTAAACCAAGGGGCTCA
TGTGGACGCCCAGACAAAGATGGGATACACACCACTGCATGTGGGCTGCCACTATGGAAATATCAAGATTGTTAATTTCCTGCTCCAGCA
TTCTGCAAAAGTTAATGCCAAAACAAAGAATGGGTATACGCCATTACATCAAGCAGCACAGCAGGGGCATACGCATATAATAAATGTCTT
ACTTCAGAACAACGCCTCCCCCAATGAACTCACTGTGAATGGGAATACTGCCCTTGGCATTGCCCGGCGCCTCGGCTACATCTCAGTAGT
GGACACCCTGAAGATAGTGACCGAAGAGACCATGACCACAACTACTGTCACAGAGAAGCACAAAATGAATGTTCCAGAAACGATGAATGA
AGTTCTTGATATGTCTGATGATGAAGTTCGTAAAGCCAATGCCCCTGAAATGCTCAGTGATGGCGAATATATCTCAGATGTTGAAGAAGG
TAATAGATGCACATGGTACAAAATTCCCAAGGTACAAGAGTTTACGGTGAAAAGTGAAGATGCAATGACCGGGGACACAGACAAATATCT
TGGGCCACAGGACCTTAAGGAATTGGGTGATGATTCCCTGCCTGCAGAGGGTTACATGGGCTTTAGTCTCGGAGCGCGTTCTGCCAGCCT
CCGCTCCTTCAGTTCGGATAGGTCTTACACCTTGAACAGAAGCTCCTATGCACGGGACAGCATGATGATTGAAGAACTCCTTGTGCCATC
CAAAGAGCAGCATCTAACATTCACAAGGGAATTTGATTCAGATTCTCTTAGACATTACAGCTGGGCTGCAGACACCTTAGACAATGTCAA
TCTTGTTTCAAGCCCCATTCATTCTGGGTTTCTGGTTAGCTTTATGGTGGACGCGAGAGGGGGCTCCATGAGAGGAAGCCGTCATCACGG
GATGAGAATCATCATTCCTCCACGCAAGTGTACGGCCCCCACTCGAATCACCTGCCGTTTGGTAAAGAGACATAAACTGGCCAACCCACC
CCCCATGGTGGAAGGAGAGGGATTAGCCAGTAGGCTGGTAGAAATGGGTCCTGCAGGGGCACAATTTTTAGGCCCTGTCATAGTGGAAAT
CCCTCACTTTGGGTCCATGAGAGGAAAAGAGAGAGAACTCATTGTTCTTCGAAGTGAAAATGGTGAAACTTGGAAGGAGCATCAGTTTGA
CAGCAAAAATGAAGATTTAACCGAGTTACTTAATGGCATGGATGAAGAACTTGATAGCCCAGAAGAGTTAGGGAAAAAGCGTATCTGCAG
GATTATCACGAAAGATTTCCCCCAGTATTTTGCAGTGGTTTCCCGGATTAAGCAGGAAAGCAACCAGATTGGTCCTGAAGGTGGAATTCT
GAGCAGCACCACAGTGCCCCTTGTTCAAGCATCTTTCCCAGAGGGTGCCCTAACTAAAAGAATTCGAGTGGGCCTCCAGGCCCAGCCTGT
TCCAGATGAAATTGTGAAAAAGATCCTTGGAAACAAAGCAACTTTTAGCCCAATTGTCACTGTGGAACCAAGAAGACGGAAATTCCATAA
ACCAATCACAATGACCATTCCGGTGCCCCCGCCCTCAGGAGAAGGTGTATCCAATGGATACAAAGGGGACACTACACCCAATCTGCGTCT
TCTCTGTAGCATTACAGGGGGCACTTCGCCTGCTCAGTGGGAAGACATCACAGGAACAACTCCTTTGACGTTTATAAAAGATTGTGTCTC
CTTTACAACCAATGTTTCAGCCAGATTTTGGCTTGCAGACTGCCATCAAGTTTTAGAAACTGTGGGGTTAGCCACGCAACTGTACAGAGA
ATTGATATGTGTTCCATATATGGCCAAGTTTGTTGTTTTTGCCAAAATGAATGATCCCGTAGAATCTTCCTTGCGATGTTTCTGCATGAC
AGATGACAAAGTGGACAAAACTTTAGAGCAACAAGAGAATTTTGAGGAAGTCGCAAGAAGCAAAGATATTGAGGTTCTGGAAGGAAAACC
TATTTATGTTGATTGTTATGGAAATTTGGCCCCACTTACCAAAGGAGGACAGCAACTTGTTTTTAACTTTTATTCTTTCAAAGAAAATAG
ACTGCCATTTTCCATCAAGATTAGAGACACCAGCCAAGAGCCCTGTGGTCGTCTGTCTTTTCTGAAAGAACCAAAGACAACAAAAGGACT
GCCTCAAACAGCGGTTTGCAACTTAAATATCACTCTGCCAGCACATAAAAAGATTGAGAAAACAGATAGACGACAGAGCTTCGCATCCTT
AGCTTTACGTAAGCGCTACAGCTACTTGACTGAGCCTGGAATGAGTCCACAGAGTCCATGTGAACGGACAGATATCAGGATGGCAATAGT
AGCCGATCACCTGGGACTTAGTTGGACAGAACTGGCAAGGGAACTGAATTTTTCAGTGGATGAAATCAATCAAATACGTGTGGAAAATCC
AAATTCTTTAATTTCTCAGAGCTTCATGTTATTAAAAAAATGGGTTACCAGAGACGGAAAAAATGCCACAACTGATGCCTTAACTTCGGT
CTTGACAAAAATTAATCGAATAGATATAGTGACACTGCTAGAAGGACCAATATTTGATTATGGAAATATTTCAGGCACCAGAAGTTTTGC
AGATGAGAACAATGTTTTCCATGACCCTGTTGATGGTTATCCTTCCCTTCAAGTGGAACTGGAAACCCCCACAGGGTTGCACTACACACC
ACCTACCCCTTTCCAGCAAGATGATTATTTTAGTGATATCTCTAGCATAGAATCTCCCCTTAGAACCCCTAGTAGACTGAGTGATGGGCT
AGTGCCTTCCCAGGGGAACATAGAGCATTCCGCAGATGGACCTCCAGTCGTAACTGCAGAAGACGCTTCCTTAGAAGACAGCAAACTGGA
AGACTCAGTGCCTTTAACAGAAATGCCTGAAGCAGTGGATGTAGATGAGAGCCAGTTGGAGAATGTATGTCTGAGTTGGCAGAATGAGAC
ATCAAGTGGAAACCTAGAGTCCTGCGCTCAAGCTCGAAGAGTAACTGGTGGGTTACTAGATCGACTGGATGACAGCCCTGACCAGTGTAG
AGATTCCATTACCTCATATCTCAAAGGAGAAGCTGGCAAATTTGAAGCAAATGGAAGCCATACAGAAATCACTCCAGAAGCAAAGACAAA
ATCTTACTTTCCAGAATCCCAAAATGATGTAGGAAAACAGAGTACCAAGGAAACTCTGAAACCAAAAATACATGGATCTGGTCATGTTGA
AGAACCAGCATCACCACTAGCAGCATATCAGAAATCTCTAGAAGAAACCAGCAAGCTTATAATAGAAGAGACTAAACCCTGTGTGCCTGT
CAGTATGAAAAAGATGAGTAGGACTTCTCCAGCAGATGGCAAGCCAAGGCTTAGCCTCCATGAAGAAGAGGGGTCCAGTGGGTCTGAGCA
AAAGAATTCATAATGCACTTAAAGGAATTCCAGATGACAGAGATGGGCTGTTCGATACAATACAGCGCTCGAAGAATCACTATCAAAAAC
GAGCATATCAGTGCATAAAATGTATGGTAGCTCTATTTAGCAGTTGTCCTGTTGCTTACCAGATCTTACAGGGTAACGGAGATCTTAAAA
GAAAATGGACCTGGGCAGTGGAATGGCTAGGAGATGAACTTGAAAGAAGACCATATACTGGCAATCCTCAGTATAGTTACAACAATTGGT
CTCCTCCAGTACAAAGCAATGAAACAGCAAATGGTTATTTCTTAGAAAGATCACATAGTGCTAGGATGACACTTGCAAAAGCTTGTGAAC
TCTGTCCAGAAGAGGAGCCAGATGACCAGGATGCCCCAGATGAGCATGAGCCCTCTCCATCAGAAGATGCCCCATTATATCCTCATTCAC
CTGCCTCTCAGTATCAACAGAATAATCATGTACATGGACAGCCATATACAGGACCAGCAGCACATCACTTGAACAACCCTCAGAAAACAG
GCCAACGAACACAAGAAAATTATGAAGGCAATGAAGAAGTATCCTCACCTCAGATGAAGGATCAGTGAAAAGCAATAATTAACTGCTTCC
TTTATGACTATGCACTAAGGTCTTATAGTCCAAACTTTCTCTGTGTCTGGCTAGTATTGAAAACTAGATAAACTGCTCCAAACCAACATG
GAGTAAAGAGCATATTCACTGGTTTATTTGCAGTAATTTGCAATTTGTCAGTGTATAAGACACATGCAGGGTGAAGTGTACAGAGTTTTG
TAACAAATGACTGGTCCTAATCTGTAAATGAGAAAGGTATATATACTATGTTAATGTCTGACTGTTAATTCTTAAGCAAGAAACTTTTTT
TGATGAAAACAAGTCAGATCTACACAGTCACACAATTATTTTTTGTTGTGTTCACTACATTGTGCAATTGATATTGCCTGCTTTGAGCAG
TTTGGTCAACTTACCAACTTCCCCCCAAAAAAGGGAACATAAAAGAGCCCATCTTTGTCAGTTTACACCAATAGTTTCTTGTTAATCCTT
CTTTCCTGGATATATAAGGCTGGTGGTAACTTTTGAATTATATGGTTGATGTGGAAAATTGGCAGTGTAACATTTCTAGATACTTTTCAT
TACCTTTTTATTCTGGTATATAGGCTAACCACTTTAAAGCTATTCTTATGCTGTAACAGTTAGCATGGCTTCACACTGTTTGTGTAGCCA
AGAGGACAGAATTACATGAATGACAGTGCCCAGAGTGACAGCTGTATATTGCTCAGAGCTTTTATTTCTTATACCTAGAATAAATATAAA
ATGGGGGAAAAATGTGACAGACAAGCAGTTTTTCATTGCACACATATTCTTCACATTTAATGTTTGATAGTTCAATTTCTTGAGCTGAAG
AATATCAAAGTATCGATAATACGAATTTTAAAATATTAAAACCAATACACAAAATTTTCCTATGTCAGAATGTGGTGGAGCATAATAGAT
TGTATTTGGTGTGCTTGCGATTTTTTTTTTCCATAGAATTTATTAAGTGAAGTTTCTAAAACTTTGCTTCTCCTGATCCCGGTGAAGTGT
ACATCATAAGAATCCATAGTACTTTGAAGTACCATTGCACCAAGATGTCTGACTGAATTCATAGTCACACTTTTATTTGAAAGAAAGAAT
TGTTGTAGTTTTTTTTCATTATTCTAAAACTCTTGTTGTTAGATACAAGATTTAATTAAGATCTAAGCTCCTGCTTATTTAATGTAATTC
TAAGGTACCATTTTAGAAAAAACATTTGTTTTAAGATTCCAAGAAACCTGTGAGTTAATACTATATTTAAAAGAGAATTGGTAAATTTTG
AATGTGTGTAATATTTTGGAACCTGTTTAAAAACCAAATATACCTGCAAATAGATACAGCCTATCCTATACTATTTAAATGTTTGGCTGT

>4390_4390_4_ANK3-USP9Y_ANK3_chr10_61815416_ENST00000503366_USP9Y_chrY_14968265_ENST00000338981_length(amino acids)=1848AA_BP=
MSEEPKEKNAKPAHRKRKGKKSDANASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG
NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDT
KGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLL
LDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHC
GHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGE
TALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGAS
LSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIA
TTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVG
CHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTLKIVTEETMTTTT
VTEKHKMNVPETMNEVLDMSDDEVRKANAPEMLSDGEYISDVEEGNRCTWYKIPKVQEFTVKSEDAMTGDTDKYLGPQDLKELGDDSLPA
EGYMGFSLGARSASLRSFSSDRSYTLNRSSYARDSMMIEELLVPSKEQHLTFTREFDSDSLRHYSWAADTLDNVNLVSSPIHSGFLVSFM
VDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIV
LRSENGETWKEHQFDSKNEDLTELLNGMDEELDSPEELGKKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEG
ALTKRIRVGLQAQPVPDEIVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDTTPNLRLLCSITGGTSPAQWED
ITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLATQLYRELICVPYMAKFVVFAKMNDPVESSLRCFCMTDDKVDKTLEQQENFE
EVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKTTKGLPQTAVCNLNITLPAH
KKIEKTDRRQSFASLALRKRYSYLTEPGMSPQSPCERTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWV
TRDGKNATTDALTSVLTKINRIDIVTLLEGPIFDYGNISGTRSFADENNVFHDPVDGYPSLQVELETPTGLHYTPPTPFQQDDYFSDISS
IESPLRTPSRLSDGLVPSQGNIEHSADGPPVVTAEDASLEDSKLEDSVPLTEMPEAVDVDESQLENVCLSWQNETSSGNLESCAQARRVT
GGLLDRLDDSPDQCRDSITSYLKGEAGKFEANGSHTEITPEAKTKSYFPESQNDVGKQSTKETLKPKIHGSGHVEEPASPLAAYQKSLEE

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Fusion Gene PPI Analysis for ANK3-USP9Y

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for ANK3-USP9Y

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for ANK3-USP9Y

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	ANK3	C0005586	Bipolar Disorder	8	CTD_human;PSYGENET
Hgene	ANK3	C0005587	Depression, Bipolar	3	CTD_human
Hgene	ANK3	C0024713	Manic Disorder	3	CTD_human
Hgene	ANK3	C0036341	Schizophrenia	3	PSYGENET
Hgene	ANK3	C0338831	Manic	3	CTD_human
Hgene	ANK3	C0033975	Psychotic Disorders	2	PSYGENET
Hgene	ANK3	C0525045	Mood Disorders	2	PSYGENET
Hgene	ANK3	C0015923	Fetal Alcohol Syndrome	1	CTD_human
Hgene	ANK3	C0024121	Lung Neoplasms	1	CTD_human
Hgene	ANK3	C0033300	Progeria	1	CTD_human
Hgene	ANK3	C0038220	Status Epilepticus	1	CTD_human
Hgene	ANK3	C0178417	Anhedonia	1	PSYGENET
Hgene	ANK3	C0242379	Malignant neoplasm of lung	1	CTD_human
Hgene	ANK3	C0270823	Petit mal status	1	CTD_human
Hgene	ANK3	C0311335	Grand Mal Status Epilepticus	1	CTD_human
Hgene	ANK3	C0349204	Nonorganic psychosis	1	PSYGENET
Hgene	ANK3	C0393734	Complex Partial Status Epilepticus	1	CTD_human
Hgene	ANK3	C0751522	Status Epilepticus, Subclinical	1	CTD_human
Hgene	ANK3	C0751523	Non-Convulsive Status Epilepticus	1	CTD_human
Hgene	ANK3	C0751524	Simple Partial Status Epilepticus	1	CTD_human
Hgene	ANK3	C0814154	Alcohol Related Neurodevelopmental Disorder	1	CTD_human
Hgene	ANK3	C2985290	Fetal Alcohol Spectrum Disorders	1	CTD_human
Hgene	ANK3	C3146244	Alcohol Related Birth Defect	1	CTD_human
Hgene	ANK3	C3661483	Partial Fetal Alcohol Syndrome	1	CTD_human
Hgene	ANK3	C3809672	MENTAL RETARDATION, AUTOSOMAL RECESSIVE 37	1	CTD_human;GENOMICS_ENGLAND;ORPHANET
Tgene		C1507149	Partial chromosome Y deletion	3	ORPHANET
Tgene		C2931163	Male sterility due to Y-chromosome deletions	3	ORPHANET

Fusion Gene Studies in Kim Lab

Fusion gene:ANK3-USP9Y (FusionGDB2 ID:HG288TG8287)

Fusion Gene Summary for ANK3-USP9Y

Fusion Gene ORF analysis for ANK3-USP9Y

Fusion Genomic Features for ANK3-USP9Y

Fusion Protein Features for ANK3-USP9Y

Fusion Gene Sequence for ANK3-USP9Y

Fusion Gene PPI Analysis for ANK3-USP9Y

Related Drugs for ANK3-USP9Y

Related Diseases for ANK3-USP9Y

Fusion Gene Studies
in Kim Lab