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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ABR-SMG6 (FusionGDB2 ID:HG29TG23293)

Fusion Gene Summary for ABR-SMG6

check button Fusion gene summary
Fusion gene informationFusion gene name: ABR-SMG6
Fusion gene ID: hg29tg23293
HgeneTgene
Gene symbol

ABR

SMG6

Gene ID

29

23293

Gene nameABR activator of RhoGEF and GTPaseSMG6 nonsense mediated mRNA decay factor
SynonymsMDBC17orf31|EST1A|SMG-6|hSMG5/7a
Cytomap('ABR')('SMG6')

17p13.3

17p13.3

Type of geneprotein-codingprotein-coding
Descriptionactive breakpoint cluster region-related proteinABR, RhoGEF and GTPase activating proteinactive BCR-relatedtelomerase-binding protein EST1AEST1 telomerase component homolog Aever shorter telomeres 1Asmg-6 homolog, nonsense mediated mRNA decay factortelomerase subunit EST1A
Modification date2020031320200320
UniProtAcc

Q12979

.
Ensembl transtripts involved in fusion geneENST00000291107, ENST00000302538, 
ENST00000536794, ENST00000544583, 
ENST00000574437, ENST00000543210, 
ENST00000572441, ENST00000573895, 
Fusion gene scores* DoF score23 X 15 X 14=483021 X 16 X 8=2688
# samples 3622
** MAII scorelog2(36/4830*10)=-3.74595437739346
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(22/2688*10)=-3.6109577092541
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ABR [Title/Abstract] AND SMG6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointABR(953289)-SMG6(1989195), # samples:1
Anticipated loss of major functional domain due to fusion event.ABR-SMG6 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABR-SMG6 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABR-SMG6 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ABR-SMG6 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ABR-SMG6 seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF.
ABR-SMG6 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
ABR-SMG6 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneABR

GO:0090630

activation of GTPase activity

7479768

TgeneSMG6

GO:1904354

negative regulation of telomere capping

12676087


check buttonFusion gene breakpoints across ABR (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across SMG6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-61-2012ABRchr17

953289

-SMG6chr17

1989195

-


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Fusion Gene ORF analysis for ABR-SMG6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000291107ENST00000573166ABRchr17

953289

-SMG6chr17

1989195

-
5CDS-5UTRENST00000302538ENST00000573166ABRchr17

953289

-SMG6chr17

1989195

-
5CDS-5UTRENST00000536794ENST00000573166ABRchr17

953289

-SMG6chr17

1989195

-
5CDS-5UTRENST00000544583ENST00000573166ABRchr17

953289

-SMG6chr17

1989195

-
5CDS-5UTRENST00000574437ENST00000573166ABRchr17

953289

-SMG6chr17

1989195

-
Frame-shiftENST00000544583ENST00000263073ABRchr17

953289

-SMG6chr17

1989195

-
Frame-shiftENST00000544583ENST00000354901ABRchr17

953289

-SMG6chr17

1989195

-
Frame-shiftENST00000544583ENST00000536871ABRchr17

953289

-SMG6chr17

1989195

-
Frame-shiftENST00000544583ENST00000544865ABRchr17

953289

-SMG6chr17

1989195

-
In-frameENST00000291107ENST00000263073ABRchr17

953289

-SMG6chr17

1989195

-
In-frameENST00000291107ENST00000354901ABRchr17

953289

-SMG6chr17

1989195

-
In-frameENST00000291107ENST00000536871ABRchr17

953289

-SMG6chr17

1989195

-
In-frameENST00000291107ENST00000544865ABRchr17

953289

-SMG6chr17

1989195

-
In-frameENST00000302538ENST00000263073ABRchr17

953289

-SMG6chr17

1989195

-
In-frameENST00000302538ENST00000354901ABRchr17

953289

-SMG6chr17

1989195

-
In-frameENST00000302538ENST00000536871ABRchr17

953289

-SMG6chr17

1989195

-
In-frameENST00000302538ENST00000544865ABRchr17

953289

-SMG6chr17

1989195

-
In-frameENST00000536794ENST00000263073ABRchr17

953289

-SMG6chr17

1989195

-
In-frameENST00000536794ENST00000354901ABRchr17

953289

-SMG6chr17

1989195

-
In-frameENST00000536794ENST00000536871ABRchr17

953289

-SMG6chr17

1989195

-
In-frameENST00000536794ENST00000544865ABRchr17

953289

-SMG6chr17

1989195

-
In-frameENST00000574437ENST00000263073ABRchr17

953289

-SMG6chr17

1989195

-
In-frameENST00000574437ENST00000354901ABRchr17

953289

-SMG6chr17

1989195

-
In-frameENST00000574437ENST00000536871ABRchr17

953289

-SMG6chr17

1989195

-
In-frameENST00000574437ENST00000544865ABRchr17

953289

-SMG6chr17

1989195

-
intron-3CDSENST00000543210ENST00000263073ABRchr17

953289

-SMG6chr17

1989195

-
intron-3CDSENST00000543210ENST00000354901ABRchr17

953289

-SMG6chr17

1989195

-
intron-3CDSENST00000543210ENST00000536871ABRchr17

953289

-SMG6chr17

1989195

-
intron-3CDSENST00000543210ENST00000544865ABRchr17

953289

-SMG6chr17

1989195

-
intron-3CDSENST00000572441ENST00000263073ABRchr17

953289

-SMG6chr17

1989195

-
intron-3CDSENST00000572441ENST00000354901ABRchr17

953289

-SMG6chr17

1989195

-
intron-3CDSENST00000572441ENST00000536871ABRchr17

953289

-SMG6chr17

1989195

-
intron-3CDSENST00000572441ENST00000544865ABRchr17

953289

-SMG6chr17

1989195

-
intron-3CDSENST00000573895ENST00000263073ABRchr17

953289

-SMG6chr17

1989195

-
intron-3CDSENST00000573895ENST00000354901ABRchr17

953289

-SMG6chr17

1989195

-
intron-3CDSENST00000573895ENST00000536871ABRchr17

953289

-SMG6chr17

1989195

-
intron-3CDSENST00000573895ENST00000544865ABRchr17

953289

-SMG6chr17

1989195

-
intron-5UTRENST00000543210ENST00000573166ABRchr17

953289

-SMG6chr17

1989195

-
intron-5UTRENST00000572441ENST00000573166ABRchr17

953289

-SMG6chr17

1989195

-
intron-5UTRENST00000573895ENST00000573166ABRchr17

953289

-SMG6chr17

1989195

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000302538ABRchr17953289-ENST00000544865SMG6chr171989195-449419381472840897
ENST00000302538ABRchr17953289-ENST00000263073SMG6chr171989195-449019381472840897
ENST00000302538ABRchr17953289-ENST00000354901SMG6chr171989195-448319381472840897
ENST00000302538ABRchr17953289-ENST00000536871SMG6chr171989195-292819381472840897
ENST00000574437ABRchr17953289-ENST00000544865SMG6chr171989195-467421181233020965
ENST00000574437ABRchr17953289-ENST00000263073SMG6chr171989195-467021181233020965
ENST00000574437ABRchr17953289-ENST00000354901SMG6chr171989195-466321181233020965
ENST00000574437ABRchr17953289-ENST00000536871SMG6chr171989195-310821181233020965
ENST00000291107ABRchr17953289-ENST00000544865SMG6chr171989195-42681712322614860
ENST00000291107ABRchr17953289-ENST00000263073SMG6chr171989195-42641712322614860
ENST00000291107ABRchr17953289-ENST00000354901SMG6chr171989195-42571712322614860
ENST00000291107ABRchr17953289-ENST00000536871SMG6chr171989195-27021712322614860
ENST00000536794ABRchr17953289-ENST00000544865SMG6chr171989195-398014241402326728
ENST00000536794ABRchr17953289-ENST00000263073SMG6chr171989195-397614241402326728
ENST00000536794ABRchr17953289-ENST00000354901SMG6chr171989195-396914241402326728
ENST00000536794ABRchr17953289-ENST00000536871SMG6chr171989195-241414241402326728

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000302538ENST00000544865ABRchr17953289-SMG6chr171989195-0.0012332930.9987668
ENST00000302538ENST00000263073ABRchr17953289-SMG6chr171989195-0.0012390130.99876106
ENST00000302538ENST00000354901ABRchr17953289-SMG6chr171989195-0.0012287210.99877125
ENST00000302538ENST00000536871ABRchr17953289-SMG6chr171989195-0.0030254350.9969746
ENST00000574437ENST00000544865ABRchr17953289-SMG6chr171989195-0.0019898420.9980102
ENST00000574437ENST00000263073ABRchr17953289-SMG6chr171989195-0.0020007960.99799913
ENST00000574437ENST00000354901ABRchr17953289-SMG6chr171989195-0.0019861830.99801385
ENST00000574437ENST00000536871ABRchr17953289-SMG6chr171989195-0.0044333930.99556655
ENST00000291107ENST00000544865ABRchr17953289-SMG6chr171989195-0.0026831270.9973169
ENST00000291107ENST00000263073ABRchr17953289-SMG6chr171989195-0.0026940260.997306
ENST00000291107ENST00000354901ABRchr17953289-SMG6chr171989195-0.0026732260.99732673
ENST00000291107ENST00000536871ABRchr17953289-SMG6chr171989195-0.0060711050.9939289
ENST00000536794ENST00000544865ABRchr17953289-SMG6chr171989195-0.0072966030.99270344
ENST00000536794ENST00000263073ABRchr17953289-SMG6chr171989195-0.0073414040.99265856
ENST00000536794ENST00000354901ABRchr17953289-SMG6chr171989195-0.0072782450.99272174
ENST00000536794ENST00000536871ABRchr17953289-SMG6chr171989195-0.0152464250.9847536

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Fusion Genomic Features for ABR-SMG6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ABR-SMG6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:953289/chr17:1989195)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ABR

Q12979

.
FUNCTION: Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. The C-terminus is a GTPase-activating protein domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form (PubMed:7479768, PubMed:17116687). The central Dbl homology (DH) domain functions as guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1. Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound to the GTP-bound form (PubMed:7479768). Functions as an important negative regulator of neuronal RAC1 activity (By similarity). Regulates macrophage functions such as CSF-1 directed motility and phagocytosis through the modulation of RAC1 activity (By similarity). {ECO:0000250|UniProtKB:Q5SSL4, ECO:0000269|PubMed:17116687, ECO:0000269|PubMed:7479768}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABRchr17:953289chr17:1989195ENST00000291107-1522417_420560823.0Compositional biasNote=Poly-Leu
HgeneABRchr17:953289chr17:1989195ENST00000302538-1623417_420597860.0Compositional biasNote=Poly-Leu
HgeneABRchr17:953289chr17:1989195ENST00000544583-1623417_420551814.0Compositional biasNote=Poly-Leu
HgeneABRchr17:953289chr17:1989195ENST00000574437-1522417_420551814.0Compositional biasNote=Poly-Leu
HgeneABRchr17:953289chr17:1989195ENST00000291107-1522301_459560823.0DomainPH
HgeneABRchr17:953289chr17:1989195ENST00000291107-152291_284560823.0DomainDH
HgeneABRchr17:953289chr17:1989195ENST00000302538-1623301_459597860.0DomainPH
HgeneABRchr17:953289chr17:1989195ENST00000302538-162391_284597860.0DomainDH
HgeneABRchr17:953289chr17:1989195ENST00000544583-1623301_459551814.0DomainPH
HgeneABRchr17:953289chr17:1989195ENST00000544583-162391_284551814.0DomainDH
HgeneABRchr17:953289chr17:1989195ENST00000574437-1522301_459551814.0DomainPH
HgeneABRchr17:953289chr17:1989195ENST00000574437-152291_284551814.0DomainDH
TgeneSMG6chr17:953289chr17:1989195ENST0000026307312191197_123911191420.0Coiled coilOntology_term=ECO:0000255
TgeneSMG6chr17:953289chr17:1989195ENST000003549015121197_1239211512.0Coiled coilOntology_term=ECO:0000255
TgeneSMG6chr17:953289chr17:1989195ENST00000354901512567_625211512.0Coiled coilOntology_term=ECO:0000255
TgeneSMG6chr17:953289chr17:1989195ENST000005368714111197_1239211512.0Coiled coilOntology_term=ECO:0000255
TgeneSMG6chr17:953289chr17:1989195ENST00000536871411567_625211512.0Coiled coilOntology_term=ECO:0000255
TgeneSMG6chr17:953289chr17:1989195ENST0000054486512191197_123910881389.0Coiled coilOntology_term=ECO:0000255
TgeneSMG6chr17:953289chr17:1989195ENST0000026307312191246_139711191420.0DomainNote=PINc
TgeneSMG6chr17:953289chr17:1989195ENST000003549015121246_1397211512.0DomainNote=PINc
TgeneSMG6chr17:953289chr17:1989195ENST000005368714111246_1397211512.0DomainNote=PINc
TgeneSMG6chr17:953289chr17:1989195ENST0000054486512191246_139710881389.0DomainNote=PINc

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABRchr17:953289chr17:1989195ENST00000543210-18417_4200311.0Compositional biasNote=Poly-Leu
HgeneABRchr17:953289chr17:1989195ENST00000291107-1522484_613560823.0DomainC2
HgeneABRchr17:953289chr17:1989195ENST00000291107-1522647_845560823.0DomainRho-GAP
HgeneABRchr17:953289chr17:1989195ENST00000302538-1623484_613597860.0DomainC2
HgeneABRchr17:953289chr17:1989195ENST00000302538-1623647_845597860.0DomainRho-GAP
HgeneABRchr17:953289chr17:1989195ENST00000543210-18301_4590311.0DomainPH
HgeneABRchr17:953289chr17:1989195ENST00000543210-18484_6130311.0DomainC2
HgeneABRchr17:953289chr17:1989195ENST00000543210-18647_8450311.0DomainRho-GAP
HgeneABRchr17:953289chr17:1989195ENST00000543210-1891_2840311.0DomainDH
HgeneABRchr17:953289chr17:1989195ENST00000544583-1623484_613551814.0DomainC2
HgeneABRchr17:953289chr17:1989195ENST00000544583-1623647_845551814.0DomainRho-GAP
HgeneABRchr17:953289chr17:1989195ENST00000574437-1522484_613551814.0DomainC2
HgeneABRchr17:953289chr17:1989195ENST00000574437-1522647_845551814.0DomainRho-GAP
TgeneSMG6chr17:953289chr17:1989195ENST000002630731219163_19311191420.0Coiled coilOntology_term=ECO:0000255
TgeneSMG6chr17:953289chr17:1989195ENST000002630731219567_62511191420.0Coiled coilOntology_term=ECO:0000255
TgeneSMG6chr17:953289chr17:1989195ENST00000354901512163_193211512.0Coiled coilOntology_term=ECO:0000255
TgeneSMG6chr17:953289chr17:1989195ENST00000536871411163_193211512.0Coiled coilOntology_term=ECO:0000255
TgeneSMG6chr17:953289chr17:1989195ENST000005448651219163_19310881389.0Coiled coilOntology_term=ECO:0000255
TgeneSMG6chr17:953289chr17:1989195ENST000005448651219567_62510881389.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for ABR-SMG6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>561_561_1_ABR-SMG6_ABR_chr17_953289_ENST00000291107_SMG6_chr17_1989195_ENST00000263073_length(transcript)=4264nt_BP=1712nt
TTCCTGTCTGCCCTCCGCGGGCTCCGGCTGCCATGGAGGAGGAAGAGGAGGCGATAGGCTTGCTGGACAAGGTTCTGGAGGACGAAGATG
TGTTTCTCCTGGAGGAGTGCGAGCTGGGAACCCCGACCAGCCCCGGCTCAGGGTCCCCCTTCCTGGTGGCTGTGAAGGTGGAAGCAGGGA
AAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCCAGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCA
TGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTCACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCT
ATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTGCAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGC
TGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTATAAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACC
AGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAGGACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGCTCTGCTCT
ACAAGCCCATTGACCGGGTCACTCGGAGCACCCTAGTCCTACACGACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGC
TGCAGGATGCCCTCCGCATCTCCCAGAACTTCCTGTCCAGCATCAACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGG
GGGAGACGCGACAGCTGGTGAAGGACGGCTTCCTGGTGGAAGTGTCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATG
TCCTACTGTGTGCCAAGCTGAAGAAGACCTCTGCAGGGAAGCACCAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGT
TTCCATCCCCCGAGGAGTCTGAGGCCAGCCCCCAGGTGCACCCCTTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCC
TCAAGAGTGAAATCCAGAAGGAGAAAGCCAACAAAGGCCAGAGCCGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCC
TGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAATCGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGA
GGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGATCTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAG
GATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACCAGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTC
ATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAACCTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCA
AAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGGGATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGA
TCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAGGACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCC
AGGTTATTGCAGCTGACTGCAAAAGGGTCACAGTGCTGAAGTATTTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCA
AGGGTGGAAAGTATGTGTCAGTGGCACCCGTCCCAGACACCATGGGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGG
AGGAGGATGTGGTGATTGAAGACTTTGAGGAAGATTCAGAGGCTGAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGA
AGCTGGCTCTGGCCAGGAAGATAGCTGAGCAGCAGCGTCGCCAGGAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGA
TGGAGCTCGAAATCAGACCTTTGTTCCTCGTACCAGACACCAACGGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCA
GGAAGTACATCCTGGTGGTGCCCCTCATCGTGATCAATGAGCTGGACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCT
ACGCCCGTGTGGTACAAGAGAAGGCCCGCAAGTCCATCGAGTTCCTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGA
CCAGCCGTGGCAATGAACTCGAATCCATCGCCTTCCGCAGTGAGGACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCT
GCTGCCTCCACTACTGCAAAGACAAGGCTAAGGACTTCATGCCCGCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGT
TGACGGATGACCGGAACCTGCGTGTGAAGGCGCTCACAAGGAATGTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGG
GCTGAGGGAGCCACACTGGGGCCCCCCCCCCGTGGAACCGTTCCTGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTG
CCTGAGCCACCAATCCACCCAGACAATAAACCATCCTCTTCCAACCCACGCCACGGCCATGCTGTGGGGGACCTGCTCCTCACAGAGCCC
CTCCCAAGGATCGGGCGGAAGCTGCTGGGACCCTCCTGGGCTGCCAGGATTTAGCAGGGAGGTGGCTGGCTACAGCAACAGCAGCTGGGC
AAGCCAGATAGGCCGCCCATGCTCTCAGCCTTTCTCCCTCCCCCGTCTCATTCCAAGGCTGAGGGAGGGCCTTCTCGCCTGGGGACGCAG
CCACTTTCTCCAGTGGAGACAGGGCAGGGGTTCTGAGTTTCCGTCAGATGCAGTGAAATCACAGTTCCCTTTCATCTTCAGAACCTCTGT
CGTGAATGTGTTCAAGAGGCTTTGGTTAAGTCAGGAAGAAGTGCCCAGGGTGTGTGTCCCCAGTCTCCCTGAGGCCTGGACTCGCCCATG
AACCCAAGTCGGCTTCTAGACAGCATGTCCCTAACAGCAGCCCTGGGCCCCCACCTCTTCTACCATCCACCCCAGACTTACCACACACCC
TTCCTGCTGCTCCTCTTCCTGCCCTTATCAACCTGGGTCCCTCACACTTCGCCAGTTGCGTCCCCGTGGACAGTCATGAGTCTAGAGGAA
AGGGGCATCTGGTCTCAGGCCCGTGCTCTCGGGTGGCCTCCACCTGCTCCCTCTCTCCTCACTGGCCTTTCTTTCCGTCTAGCTTCCTCT
TCAGGAAATGTCCTGACTCCCCTCAGCTCCCCCTTCACCCCTCCTTGCCCGCCTACCCTCCCTCCAGAATAGCCCCTCACCCTTCTTCCC
CTTCTAGTTGATCCTTTTCACCTCCCTGATCCCCTTCATTTCTTCACCGCGGTTCCTCGTCATAGGGGTTCTCACTCTGAACTTTCCCTC
TCTACTACCCATGGCAGGAACCTAGTACAGGTCTCCCACCCAGGGCCTTCCACCCTCGGCTCCTGTGCTGGGAGAAACTTCCAGGCGTGG
ACAGCCCAGCCTGAGGCATTCCAGTGCTGGGGCACCGTCGCCTAACCTGGTTTCTAGCTTTGCCCTCACTCCCCGGAAAAACTGACACTG
ACACAGGGGCCCTTTCCTTGCCCCTTTAGCTGGTACCTCAGTGGGGAGGCTTCCTTACCAAGAATGAGTTCCTGAAACCCAGGGCCAGAG
ACAAGGACAACTTAGGGGAAGACGGGGTTTTCGGTGGAGCCAGGGGCAAATCTTAATGGGACCAGTGGGGGATACCCCAGAGCCCATGGC
CTGACTGCACAGCCTGCCTGGAGGATGGGTGCGCAGCTCTGCCCTCCCTGAGGCCCAGGACTATGCCAGAAGCGATGGGGTACCGTGTAG
GGGAGCCAAGGCCAGTAGTTTGGGGGTAGGAGTCCCCTAGAGTCTCAGAAGACTGGGCTCTTTGGAGTACAGGGTCCCCGGCCTCTCCTT
TAAGATTCTCTCCCCAGCTGGAAGGCCGATGACTGGGTGGTCGGGAGGGAGACCCAGCTCTCCTTTCTGTCCCGTTTGCAGCACTGGTTT
TGTTTCCTTAATAAATTTTTAGTTATGAAACATA

>561_561_1_ABR-SMG6_ABR_chr17_953289_ENST00000291107_SMG6_chr17_1989195_ENST00000263073_length(amino acids)=860AA_BP=560
MEEEEEAIGLLDKVLEDEDVFLLEECELGTPTSPGSGSPFLVAVKVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATTS
QPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKV
KGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGF
LVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKAN
KGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHN
IPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKT
KVNKDNNEIVDKIMGKGQIQVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEE
DSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIV
INELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAK
DFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG

--------------------------------------------------------------
>561_561_2_ABR-SMG6_ABR_chr17_953289_ENST00000291107_SMG6_chr17_1989195_ENST00000354901_length(transcript)=4257nt_BP=1712nt
TTCCTGTCTGCCCTCCGCGGGCTCCGGCTGCCATGGAGGAGGAAGAGGAGGCGATAGGCTTGCTGGACAAGGTTCTGGAGGACGAAGATG
TGTTTCTCCTGGAGGAGTGCGAGCTGGGAACCCCGACCAGCCCCGGCTCAGGGTCCCCCTTCCTGGTGGCTGTGAAGGTGGAAGCAGGGA
AAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCCAGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCA
TGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTCACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCT
ATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTGCAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGC
TGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTATAAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACC
AGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAGGACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGCTCTGCTCT
ACAAGCCCATTGACCGGGTCACTCGGAGCACCCTAGTCCTACACGACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGC
TGCAGGATGCCCTCCGCATCTCCCAGAACTTCCTGTCCAGCATCAACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGG
GGGAGACGCGACAGCTGGTGAAGGACGGCTTCCTGGTGGAAGTGTCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATG
TCCTACTGTGTGCCAAGCTGAAGAAGACCTCTGCAGGGAAGCACCAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGT
TTCCATCCCCCGAGGAGTCTGAGGCCAGCCCCCAGGTGCACCCCTTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCC
TCAAGAGTGAAATCCAGAAGGAGAAAGCCAACAAAGGCCAGAGCCGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCC
TGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAATCGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGA
GGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGATCTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAG
GATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACCAGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTC
ATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAACCTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCA
AAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGGGATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGA
TCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAGGACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCC
AGGTTATTGCAGCTGACTGCAAAAGGGTCACAGTGCTGAAGTATTTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCA
AGGGTGGAAAGTATGTGTCAGTGGCACCCGTCCCAGACACCATGGGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGG
AGGAGGATGTGGTGATTGAAGACTTTGAGGAAGATTCAGAGGCTGAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGA
AGCTGGCTCTGGCCAGGAAGATAGCTGAGCAGCAGCGTCGCCAGGAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGA
TGGAGCTCGAAATCAGACCTTTGTTCCTCGTACCAGACACCAACGGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCA
GGAAGTACATCCTGGTGGTGCCCCTCATCGTGATCAATGAGCTGGACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCT
ACGCCCGTGTGGTACAAGAGAAGGCCCGCAAGTCCATCGAGTTCCTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGA
CCAGCCGTGGCAATGAACTCGAATCCATCGCCTTCCGCAGTGAGGACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCT
GCTGCCTCCACTACTGCAAAGACAAGGCTAAGGACTTCATGCCCGCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGT
TGACGGATGACCGGAACCTGCGTGTGAAGGCGCTCACAAGGAATGTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGG
GCTGAGGGAGCCACACTGGGGCCCCCCCCCCGTGGAACCGTTCCTGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTG
CCTGAGCCACCAATCCACCCAGACAATAAACCATCCTCTTCCAACCCACGCCACGGCCATGCTGTGGGGGACCTGCTCCTCACAGAGCCC
CTCCCAAGGATCGGGCGGAAGCTGCTGGGACCCTCCTGGGCTGCCAGGATTTAGCAGGGAGGTGGCTGGCTACAGCAACAGCAGCTGGGC
AAGCCAGATAGGCCGCCCATGCTCTCAGCCTTTCTCCCTCCCCCGTCTCATTCCAAGGCTGAGGGAGGGCCTTCTCGCCTGGGGACGCAG
CCACTTTCTCCAGTGGAGACAGGGCAGGGGTTCTGAGTTTCCGTCAGATGCAGTGAAATCACAGTTCCCTTTCATCTTCAGAACCTCTGT
CGTGAATGTGTTCAAGAGGCTTTGGTTAAGTCAGGAAGAAGTGCCCAGGGTGTGTGTCCCCAGTCTCCCTGAGGCCTGGACTCGCCCATG
AACCCAAGTCGGCTTCTAGACAGCATGTCCCTAACAGCAGCCCTGGGCCCCCACCTCTTCTACCATCCACCCCAGACTTACCACACACCC
TTCCTGCTGCTCCTCTTCCTGCCCTTATCAACCTGGGTCCCTCACACTTCGCCAGTTGCGTCCCCGTGGACAGTCATGAGTCTAGAGGAA
AGGGGCATCTGGTCTCAGGCCCGTGCTCTCGGGTGGCCTCCACCTGCTCCCTCTCTCCTCACTGGCCTTTCTTTCCGTCTAGCTTCCTCT
TCAGGAAATGTCCTGACTCCCCTCAGCTCCCCCTTCACCCCTCCTTGCCCGCCTACCCTCCCTCCAGAATAGCCCCTCACCCTTCTTCCC
CTTCTAGTTGATCCTTTTCACCTCCCTGATCCCCTTCATTTCTTCACCGCGGTTCCTCGTCATAGGGGTTCTCACTCTGAACTTTCCCTC
TCTACTACCCATGGCAGGAACCTAGTACAGGTCTCCCACCCAGGGCCTTCCACCCTCGGCTCCTGTGCTGGGAGAAACTTCCAGGCGTGG
ACAGCCCAGCCTGAGGCATTCCAGTGCTGGGGCACCGTCGCCTAACCTGGTTTCTAGCTTTGCCCTCACTCCCCGGAAAAACTGACACTG
ACACAGGGGCCCTTTCCTTGCCCCTTTAGCTGGTACCTCAGTGGGGAGGCTTCCTTACCAAGAATGAGTTCCTGAAACCCAGGGCCAGAG
ACAAGGACAACTTAGGGGAAGACGGGGTTTTCGGTGGAGCCAGGGGCAAATCTTAATGGGACCAGTGGGGGATACCCCAGAGCCCATGGC
CTGACTGCACAGCCTGCCTGGAGGATGGGTGCGCAGCTCTGCCCTCCCTGAGGCCCAGGACTATGCCAGAAGCGATGGGGTACCGTGTAG
GGGAGCCAAGGCCAGTAGTTTGGGGGTAGGAGTCCCCTAGAGTCTCAGAAGACTGGGCTCTTTGGAGTACAGGGTCCCCGGCCTCTCCTT
TAAGATTCTCTCCCCAGCTGGAAGGCCGATGACTGGGTGGTCGGGAGGGAGACCCAGCTCTCCTTTCTGTCCCGTTTGCAGCACTGGTTT
TGTTTCCTTAATAAATTTTTAGTTATG

>561_561_2_ABR-SMG6_ABR_chr17_953289_ENST00000291107_SMG6_chr17_1989195_ENST00000354901_length(amino acids)=860AA_BP=560
MEEEEEAIGLLDKVLEDEDVFLLEECELGTPTSPGSGSPFLVAVKVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATTS
QPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKV
KGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGF
LVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKAN
KGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHN
IPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKT
KVNKDNNEIVDKIMGKGQIQVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEE
DSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIV
INELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAK
DFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG

--------------------------------------------------------------
>561_561_3_ABR-SMG6_ABR_chr17_953289_ENST00000291107_SMG6_chr17_1989195_ENST00000536871_length(transcript)=2702nt_BP=1712nt
TTCCTGTCTGCCCTCCGCGGGCTCCGGCTGCCATGGAGGAGGAAGAGGAGGCGATAGGCTTGCTGGACAAGGTTCTGGAGGACGAAGATG
TGTTTCTCCTGGAGGAGTGCGAGCTGGGAACCCCGACCAGCCCCGGCTCAGGGTCCCCCTTCCTGGTGGCTGTGAAGGTGGAAGCAGGGA
AAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCCAGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCA
TGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTCACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCT
ATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTGCAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGC
TGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTATAAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACC
AGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAGGACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGCTCTGCTCT
ACAAGCCCATTGACCGGGTCACTCGGAGCACCCTAGTCCTACACGACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGC
TGCAGGATGCCCTCCGCATCTCCCAGAACTTCCTGTCCAGCATCAACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGG
GGGAGACGCGACAGCTGGTGAAGGACGGCTTCCTGGTGGAAGTGTCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATG
TCCTACTGTGTGCCAAGCTGAAGAAGACCTCTGCAGGGAAGCACCAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGT
TTCCATCCCCCGAGGAGTCTGAGGCCAGCCCCCAGGTGCACCCCTTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCC
TCAAGAGTGAAATCCAGAAGGAGAAAGCCAACAAAGGCCAGAGCCGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCC
TGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAATCGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGA
GGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGATCTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAG
GATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACCAGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTC
ATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAACCTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCA
AAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGGGATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGA
TCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAGGACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCC
AGGTTATTGCAGCTGACTGCAAAAGGGTCACAGTGCTGAAGTATTTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCA
AGGGTGGAAAGTATGTGTCAGTGGCACCCGTCCCAGACACCATGGGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGG
AGGAGGATGTGGTGATTGAAGACTTTGAGGAAGATTCAGAGGCTGAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGA
AGCTGGCTCTGGCCAGGAAGATAGCTGAGCAGCAGCGTCGCCAGGAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGA
TGGAGCTCGAAATCAGACCTTTGTTCCTCGTACCAGACACCAACGGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCA
GGAAGTACATCCTGGTGGTGCCCCTCATCGTGATCAATGAGCTGGACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCT
ACGCCCGTGTGGTACAAGAGAAGGCCCGCAAGTCCATCGAGTTCCTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGA
CCAGCCGTGGCAATGAACTCGAATCCATCGCCTTCCGCAGTGAGGACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCT
GCTGCCTCCACTACTGCAAAGACAAGGCTAAGGACTTCATGCCCGCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGT
TGACGGATGACCGGAACCTGCGTGTGAAGGCGCTCACAAGGAATGTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGG
GCTGAGGGAGCCACACTGGGGCCCCCCCCCCGTGGAACCGTTCCTGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTG
CC

>561_561_3_ABR-SMG6_ABR_chr17_953289_ENST00000291107_SMG6_chr17_1989195_ENST00000536871_length(amino acids)=860AA_BP=560
MEEEEEAIGLLDKVLEDEDVFLLEECELGTPTSPGSGSPFLVAVKVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATTS
QPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKV
KGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGF
LVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKAN
KGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHN
IPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKT
KVNKDNNEIVDKIMGKGQIQVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEE
DSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIV
INELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAK
DFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG

--------------------------------------------------------------
>561_561_4_ABR-SMG6_ABR_chr17_953289_ENST00000291107_SMG6_chr17_1989195_ENST00000544865_length(transcript)=4268nt_BP=1712nt
TTCCTGTCTGCCCTCCGCGGGCTCCGGCTGCCATGGAGGAGGAAGAGGAGGCGATAGGCTTGCTGGACAAGGTTCTGGAGGACGAAGATG
TGTTTCTCCTGGAGGAGTGCGAGCTGGGAACCCCGACCAGCCCCGGCTCAGGGTCCCCCTTCCTGGTGGCTGTGAAGGTGGAAGCAGGGA
AAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCCAGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCA
TGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTCACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCT
ATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTGCAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGC
TGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTATAAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACC
AGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAGGACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGCTCTGCTCT
ACAAGCCCATTGACCGGGTCACTCGGAGCACCCTAGTCCTACACGACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGC
TGCAGGATGCCCTCCGCATCTCCCAGAACTTCCTGTCCAGCATCAACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGG
GGGAGACGCGACAGCTGGTGAAGGACGGCTTCCTGGTGGAAGTGTCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATG
TCCTACTGTGTGCCAAGCTGAAGAAGACCTCTGCAGGGAAGCACCAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGT
TTCCATCCCCCGAGGAGTCTGAGGCCAGCCCCCAGGTGCACCCCTTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCC
TCAAGAGTGAAATCCAGAAGGAGAAAGCCAACAAAGGCCAGAGCCGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCC
TGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAATCGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGA
GGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGATCTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAG
GATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACCAGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTC
ATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAACCTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCA
AAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGGGATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGA
TCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAGGACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCC
AGGTTATTGCAGCTGACTGCAAAAGGGTCACAGTGCTGAAGTATTTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCA
AGGGTGGAAAGTATGTGTCAGTGGCACCCGTCCCAGACACCATGGGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGG
AGGAGGATGTGGTGATTGAAGACTTTGAGGAAGATTCAGAGGCTGAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGA
AGCTGGCTCTGGCCAGGAAGATAGCTGAGCAGCAGCGTCGCCAGGAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGA
TGGAGCTCGAAATCAGACCTTTGTTCCTCGTACCAGACACCAACGGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCA
GGAAGTACATCCTGGTGGTGCCCCTCATCGTGATCAATGAGCTGGACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCT
ACGCCCGTGTGGTACAAGAGAAGGCCCGCAAGTCCATCGAGTTCCTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGA
CCAGCCGTGGCAATGAACTCGAATCCATCGCCTTCCGCAGTGAGGACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCT
GCTGCCTCCACTACTGCAAAGACAAGGCTAAGGACTTCATGCCCGCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGT
TGACGGATGACCGGAACCTGCGTGTGAAGGCGCTCACAAGGAATGTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGG
GCTGAGGGAGCCACACTGGGGCCCCCCCCCCGTGGAACCGTTCCTGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTG
CCTGAGCCACCAATCCACCCAGACAATAAACCATCCTCTTCCAACCCACGCCACGGCCATGCTGTGGGGGACCTGCTCCTCACAGAGCCC
CTCCCAAGGATCGGGCGGAAGCTGCTGGGACCCTCCTGGGCTGCCAGGATTTAGCAGGGAGGTGGCTGGCTACAGCAACAGCAGCTGGGC
AAGCCAGATAGGCCGCCCATGCTCTCAGCCTTTCTCCCTCCCCCGTCTCATTCCAAGGCTGAGGGAGGGCCTTCTCGCCTGGGGACGCAG
CCACTTTCTCCAGTGGAGACAGGGCAGGGGTTCTGAGTTTCCGTCAGATGCAGTGAAATCACAGTTCCCTTTCATCTTCAGAACCTCTGT
CGTGAATGTGTTCAAGAGGCTTTGGTTAAGTCAGGAAGAAGTGCCCAGGGTGTGTGTCCCCAGTCTCCCTGAGGCCTGGACTCGCCCATG
AACCCAAGTCGGCTTCTAGACAGCATGTCCCTAACAGCAGCCCTGGGCCCCCACCTCTTCTACCATCCACCCCAGACTTACCACACACCC
TTCCTGCTGCTCCTCTTCCTGCCCTTATCAACCTGGGTCCCTCACACTTCGCCAGTTGCGTCCCCGTGGACAGTCATGAGTCTAGAGGAA
AGGGGCATCTGGTCTCAGGCCCGTGCTCTCGGGTGGCCTCCACCTGCTCCCTCTCTCCTCACTGGCCTTTCTTTCCGTCTAGCTTCCTCT
TCAGGAAATGTCCTGACTCCCCTCAGCTCCCCCTTCACCCCTCCTTGCCCGCCTACCCTCCCTCCAGAATAGCCCCTCACCCTTCTTCCC
CTTCTAGTTGATCCTTTTCACCTCCCTGATCCCCTTCATTTCTTCACCGCGGTTCCTCGTCATAGGGGTTCTCACTCTGAACTTTCCCTC
TCTACTACCCATGGCAGGAACCTAGTACAGGTCTCCCACCCAGGGCCTTCCACCCTCGGCTCCTGTGCTGGGAGAAACTTCCAGGCGTGG
ACAGCCCAGCCTGAGGCATTCCAGTGCTGGGGCACCGTCGCCTAACCTGGTTTCTAGCTTTGCCCTCACTCCCCGGAAAAACTGACACTG
ACACAGGGGCCCTTTCCTTGCCCCTTTAGCTGGTACCTCAGTGGGGAGGCTTCCTTACCAAGAATGAGTTCCTGAAACCCAGGGCCAGAG
ACAAGGACAACTTAGGGGAAGACGGGGTTTTCGGTGGAGCCAGGGGCAAATCTTAATGGGACCAGTGGGGGATACCCCAGAGCCCATGGC
CTGACTGCACAGCCTGCCTGGAGGATGGGTGCGCAGCTCTGCCCTCCCTGAGGCCCAGGACTATGCCAGAAGCGATGGGGTACCGTGTAG
GGGAGCCAAGGCCAGTAGTTTGGGGGTAGGAGTCCCCTAGAGTCTCAGAAGACTGGGCTCTTTGGAGTACAGGGTCCCCGGCCTCTCCTT
TAAGATTCTCTCCCCAGCTGGAAGGCCGATGACTGGGTGGTCGGGAGGGAGACCCAGCTCTCCTTTCTGTCCCGTTTGCAGCACTGGTTT
TGTTTCCTTAATAAATTTTTAGTTATGAAACATACCTG

>561_561_4_ABR-SMG6_ABR_chr17_953289_ENST00000291107_SMG6_chr17_1989195_ENST00000544865_length(amino acids)=860AA_BP=560
MEEEEEAIGLLDKVLEDEDVFLLEECELGTPTSPGSGSPFLVAVKVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATTS
QPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKV
KGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGF
LVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKAN
KGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHN
IPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKT
KVNKDNNEIVDKIMGKGQIQVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEE
DSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIV
INELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAK
DFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG

--------------------------------------------------------------
>561_561_5_ABR-SMG6_ABR_chr17_953289_ENST00000302538_SMG6_chr17_1989195_ENST00000263073_length(transcript)=4490nt_BP=1938nt
GCCCCGCGCTCCTCCCGGGGACCTGGTTCCCGGCCTCCTCGCCCCTCCGCGCTCGCAACTTCGGCCTCCCCCGGCTCCCGCCCGCTCTCC
CTCCTTTGTTGCGCGATGAGGGTCGGGTTTCGGATCTGACCGAGCCGCCGCCGCGGGATGGAGCCGCTCAGCCACCGGGGCCTGCCGCGC
CTGTCCTGGATCGACACCCTCTACAGCAACTTCAGCTACGGGACGGACGAGTACGACGGAGAGGGGAATGAGGAGCAGAAGGGGCCCCCG
GAGGGCTCAGAGACCATGCCGTACATCGATGAGTCGCCCACCATGTCCCCGCAGCTCAGCGCCCGCAGCCAGGGCGGGGGGGATGGCGTC
TCCCCGACTCCACCTGAGGGACTGGCTCCTGGGGTGGAAGCAGGGAAAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCC
AGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCATGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTC
ACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCTATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTG
CAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGCTGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTAT
AAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACCAGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAG
GACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGCTCTGCTCTACAAGCCCATTGACCGGGTCACTCGGAGCACCCTAGTCCTACAC
GACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGCTGCAGGATGCCCTCCGCATCTCCCAGAACTTCCTGTCCAGCATC
AACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGGGGGAGACGCGACAGCTGGTGAAGGACGGCTTCCTGGTGGAAGTG
TCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATGTCCTACTGTGTGCCAAGCTGAAGAAGACCTCTGCAGGGAAGCAC
CAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGTTTCCATCCCCCGAGGAGTCTGAGGCCAGCCCCCAGGTGCACCCC
TTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCCTCAAGAGTGAAATCCAGAAGGAGAAAGCCAACAAAGGCCAGAGC
CGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCCTGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAAT
CGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGAGGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGAT
CTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAGGATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACC
AGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTCATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAAC
CTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCAAAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGG
GATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAG
GACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCCAGGTTATTGCAGCTGACTGCAAAAGGGTCACAGTGCTGAAGTAT
TTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAGTATGTGTCAGTGGCACCCGTCCCAGACACCATG
GGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTGGTGATTGAAGACTTTGAGGAAGATTCAGAGGCT
GAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTGGCCAGGAAGATAGCTGAGCAGCAGCGTCGCCAG
GAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAAATCAGACCTTTGTTCCTCGTACCAGACACCAAC
GGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATCCTGGTGGTGCCCCTCATCGTGATCAATGAGCTG
GACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTGGTACAAGAGAAGGCCCGCAAGTCCATCGAGTTC
CTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGCAATGAACTCGAATCCATCGCCTTCCGCAGTGAG
GACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCACTACTGCAAAGACAAGGCTAAGGACTTCATGCCC
GCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGACCGGAACCTGCGTGTGAAGGCGCTCACAAGGAAT
GTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGGGCTGAGGGAGCCACACTGGGGCCCCCCCCCCGTGGAACCGTTCC
TGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTGCCTGAGCCACCAATCCACCCAGACAATAAACCATCCTCTTCCAA
CCCACGCCACGGCCATGCTGTGGGGGACCTGCTCCTCACAGAGCCCCTCCCAAGGATCGGGCGGAAGCTGCTGGGACCCTCCTGGGCTGC
CAGGATTTAGCAGGGAGGTGGCTGGCTACAGCAACAGCAGCTGGGCAAGCCAGATAGGCCGCCCATGCTCTCAGCCTTTCTCCCTCCCCC
GTCTCATTCCAAGGCTGAGGGAGGGCCTTCTCGCCTGGGGACGCAGCCACTTTCTCCAGTGGAGACAGGGCAGGGGTTCTGAGTTTCCGT
CAGATGCAGTGAAATCACAGTTCCCTTTCATCTTCAGAACCTCTGTCGTGAATGTGTTCAAGAGGCTTTGGTTAAGTCAGGAAGAAGTGC
CCAGGGTGTGTGTCCCCAGTCTCCCTGAGGCCTGGACTCGCCCATGAACCCAAGTCGGCTTCTAGACAGCATGTCCCTAACAGCAGCCCT
GGGCCCCCACCTCTTCTACCATCCACCCCAGACTTACCACACACCCTTCCTGCTGCTCCTCTTCCTGCCCTTATCAACCTGGGTCCCTCA
CACTTCGCCAGTTGCGTCCCCGTGGACAGTCATGAGTCTAGAGGAAAGGGGCATCTGGTCTCAGGCCCGTGCTCTCGGGTGGCCTCCACC
TGCTCCCTCTCTCCTCACTGGCCTTTCTTTCCGTCTAGCTTCCTCTTCAGGAAATGTCCTGACTCCCCTCAGCTCCCCCTTCACCCCTCC
TTGCCCGCCTACCCTCCCTCCAGAATAGCCCCTCACCCTTCTTCCCCTTCTAGTTGATCCTTTTCACCTCCCTGATCCCCTTCATTTCTT
CACCGCGGTTCCTCGTCATAGGGGTTCTCACTCTGAACTTTCCCTCTCTACTACCCATGGCAGGAACCTAGTACAGGTCTCCCACCCAGG
GCCTTCCACCCTCGGCTCCTGTGCTGGGAGAAACTTCCAGGCGTGGACAGCCCAGCCTGAGGCATTCCAGTGCTGGGGCACCGTCGCCTA
ACCTGGTTTCTAGCTTTGCCCTCACTCCCCGGAAAAACTGACACTGACACAGGGGCCCTTTCCTTGCCCCTTTAGCTGGTACCTCAGTGG
GGAGGCTTCCTTACCAAGAATGAGTTCCTGAAACCCAGGGCCAGAGACAAGGACAACTTAGGGGAAGACGGGGTTTTCGGTGGAGCCAGG
GGCAAATCTTAATGGGACCAGTGGGGGATACCCCAGAGCCCATGGCCTGACTGCACAGCCTGCCTGGAGGATGGGTGCGCAGCTCTGCCC
TCCCTGAGGCCCAGGACTATGCCAGAAGCGATGGGGTACCGTGTAGGGGAGCCAAGGCCAGTAGTTTGGGGGTAGGAGTCCCCTAGAGTC
TCAGAAGACTGGGCTCTTTGGAGTACAGGGTCCCCGGCCTCTCCTTTAAGATTCTCTCCCCAGCTGGAAGGCCGATGACTGGGTGGTCGG
GAGGGAGACCCAGCTCTCCTTTCTGTCCCGTTTGCAGCACTGGTTTTGTTTCCTTAATAAATTTTTAGTTATGAAACATA

>561_561_5_ABR-SMG6_ABR_chr17_953289_ENST00000302538_SMG6_chr17_1989195_ENST00000263073_length(amino acids)=897AA_BP=597
MEPLSHRGLPRLSWIDTLYSNFSYGTDEYDGEGNEEQKGPPEGSETMPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLE
MRKLVLSGFLASEEIYINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQ
LGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDA
LRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSP
EESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEW
REAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKT
RVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGK
YVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELE
IRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRG
NELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG

--------------------------------------------------------------
>561_561_6_ABR-SMG6_ABR_chr17_953289_ENST00000302538_SMG6_chr17_1989195_ENST00000354901_length(transcript)=4483nt_BP=1938nt
GCCCCGCGCTCCTCCCGGGGACCTGGTTCCCGGCCTCCTCGCCCCTCCGCGCTCGCAACTTCGGCCTCCCCCGGCTCCCGCCCGCTCTCC
CTCCTTTGTTGCGCGATGAGGGTCGGGTTTCGGATCTGACCGAGCCGCCGCCGCGGGATGGAGCCGCTCAGCCACCGGGGCCTGCCGCGC
CTGTCCTGGATCGACACCCTCTACAGCAACTTCAGCTACGGGACGGACGAGTACGACGGAGAGGGGAATGAGGAGCAGAAGGGGCCCCCG
GAGGGCTCAGAGACCATGCCGTACATCGATGAGTCGCCCACCATGTCCCCGCAGCTCAGCGCCCGCAGCCAGGGCGGGGGGGATGGCGTC
TCCCCGACTCCACCTGAGGGACTGGCTCCTGGGGTGGAAGCAGGGAAAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCC
AGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCATGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTC
ACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCTATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTG
CAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGCTGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTAT
AAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACCAGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAG
GACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGCTCTGCTCTACAAGCCCATTGACCGGGTCACTCGGAGCACCCTAGTCCTACAC
GACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGCTGCAGGATGCCCTCCGCATCTCCCAGAACTTCCTGTCCAGCATC
AACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGGGGGAGACGCGACAGCTGGTGAAGGACGGCTTCCTGGTGGAAGTG
TCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATGTCCTACTGTGTGCCAAGCTGAAGAAGACCTCTGCAGGGAAGCAC
CAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGTTTCCATCCCCCGAGGAGTCTGAGGCCAGCCCCCAGGTGCACCCC
TTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCCTCAAGAGTGAAATCCAGAAGGAGAAAGCCAACAAAGGCCAGAGC
CGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCCTGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAAT
CGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGAGGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGAT
CTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAGGATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACC
AGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTCATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAAC
CTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCAAAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGG
GATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAG
GACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCCAGGTTATTGCAGCTGACTGCAAAAGGGTCACAGTGCTGAAGTAT
TTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAGTATGTGTCAGTGGCACCCGTCCCAGACACCATG
GGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTGGTGATTGAAGACTTTGAGGAAGATTCAGAGGCT
GAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTGGCCAGGAAGATAGCTGAGCAGCAGCGTCGCCAG
GAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAAATCAGACCTTTGTTCCTCGTACCAGACACCAAC
GGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATCCTGGTGGTGCCCCTCATCGTGATCAATGAGCTG
GACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTGGTACAAGAGAAGGCCCGCAAGTCCATCGAGTTC
CTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGCAATGAACTCGAATCCATCGCCTTCCGCAGTGAG
GACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCACTACTGCAAAGACAAGGCTAAGGACTTCATGCCC
GCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGACCGGAACCTGCGTGTGAAGGCGCTCACAAGGAAT
GTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGGGCTGAGGGAGCCACACTGGGGCCCCCCCCCCGTGGAACCGTTCC
TGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTGCCTGAGCCACCAATCCACCCAGACAATAAACCATCCTCTTCCAA
CCCACGCCACGGCCATGCTGTGGGGGACCTGCTCCTCACAGAGCCCCTCCCAAGGATCGGGCGGAAGCTGCTGGGACCCTCCTGGGCTGC
CAGGATTTAGCAGGGAGGTGGCTGGCTACAGCAACAGCAGCTGGGCAAGCCAGATAGGCCGCCCATGCTCTCAGCCTTTCTCCCTCCCCC
GTCTCATTCCAAGGCTGAGGGAGGGCCTTCTCGCCTGGGGACGCAGCCACTTTCTCCAGTGGAGACAGGGCAGGGGTTCTGAGTTTCCGT
CAGATGCAGTGAAATCACAGTTCCCTTTCATCTTCAGAACCTCTGTCGTGAATGTGTTCAAGAGGCTTTGGTTAAGTCAGGAAGAAGTGC
CCAGGGTGTGTGTCCCCAGTCTCCCTGAGGCCTGGACTCGCCCATGAACCCAAGTCGGCTTCTAGACAGCATGTCCCTAACAGCAGCCCT
GGGCCCCCACCTCTTCTACCATCCACCCCAGACTTACCACACACCCTTCCTGCTGCTCCTCTTCCTGCCCTTATCAACCTGGGTCCCTCA
CACTTCGCCAGTTGCGTCCCCGTGGACAGTCATGAGTCTAGAGGAAAGGGGCATCTGGTCTCAGGCCCGTGCTCTCGGGTGGCCTCCACC
TGCTCCCTCTCTCCTCACTGGCCTTTCTTTCCGTCTAGCTTCCTCTTCAGGAAATGTCCTGACTCCCCTCAGCTCCCCCTTCACCCCTCC
TTGCCCGCCTACCCTCCCTCCAGAATAGCCCCTCACCCTTCTTCCCCTTCTAGTTGATCCTTTTCACCTCCCTGATCCCCTTCATTTCTT
CACCGCGGTTCCTCGTCATAGGGGTTCTCACTCTGAACTTTCCCTCTCTACTACCCATGGCAGGAACCTAGTACAGGTCTCCCACCCAGG
GCCTTCCACCCTCGGCTCCTGTGCTGGGAGAAACTTCCAGGCGTGGACAGCCCAGCCTGAGGCATTCCAGTGCTGGGGCACCGTCGCCTA
ACCTGGTTTCTAGCTTTGCCCTCACTCCCCGGAAAAACTGACACTGACACAGGGGCCCTTTCCTTGCCCCTTTAGCTGGTACCTCAGTGG
GGAGGCTTCCTTACCAAGAATGAGTTCCTGAAACCCAGGGCCAGAGACAAGGACAACTTAGGGGAAGACGGGGTTTTCGGTGGAGCCAGG
GGCAAATCTTAATGGGACCAGTGGGGGATACCCCAGAGCCCATGGCCTGACTGCACAGCCTGCCTGGAGGATGGGTGCGCAGCTCTGCCC
TCCCTGAGGCCCAGGACTATGCCAGAAGCGATGGGGTACCGTGTAGGGGAGCCAAGGCCAGTAGTTTGGGGGTAGGAGTCCCCTAGAGTC
TCAGAAGACTGGGCTCTTTGGAGTACAGGGTCCCCGGCCTCTCCTTTAAGATTCTCTCCCCAGCTGGAAGGCCGATGACTGGGTGGTCGG
GAGGGAGACCCAGCTCTCCTTTCTGTCCCGTTTGCAGCACTGGTTTTGTTTCCTTAATAAATTTTTAGTTATG

>561_561_6_ABR-SMG6_ABR_chr17_953289_ENST00000302538_SMG6_chr17_1989195_ENST00000354901_length(amino acids)=897AA_BP=597
MEPLSHRGLPRLSWIDTLYSNFSYGTDEYDGEGNEEQKGPPEGSETMPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLE
MRKLVLSGFLASEEIYINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQ
LGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDA
LRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSP
EESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEW
REAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKT
RVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGK
YVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELE
IRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRG
NELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG

--------------------------------------------------------------
>561_561_7_ABR-SMG6_ABR_chr17_953289_ENST00000302538_SMG6_chr17_1989195_ENST00000536871_length(transcript)=2928nt_BP=1938nt
GCCCCGCGCTCCTCCCGGGGACCTGGTTCCCGGCCTCCTCGCCCCTCCGCGCTCGCAACTTCGGCCTCCCCCGGCTCCCGCCCGCTCTCC
CTCCTTTGTTGCGCGATGAGGGTCGGGTTTCGGATCTGACCGAGCCGCCGCCGCGGGATGGAGCCGCTCAGCCACCGGGGCCTGCCGCGC
CTGTCCTGGATCGACACCCTCTACAGCAACTTCAGCTACGGGACGGACGAGTACGACGGAGAGGGGAATGAGGAGCAGAAGGGGCCCCCG
GAGGGCTCAGAGACCATGCCGTACATCGATGAGTCGCCCACCATGTCCCCGCAGCTCAGCGCCCGCAGCCAGGGCGGGGGGGATGGCGTC
TCCCCGACTCCACCTGAGGGACTGGCTCCTGGGGTGGAAGCAGGGAAAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCC
AGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCATGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTC
ACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCTATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTG
CAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGCTGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTAT
AAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACCAGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAG
GACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGCTCTGCTCTACAAGCCCATTGACCGGGTCACTCGGAGCACCCTAGTCCTACAC
GACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGCTGCAGGATGCCCTCCGCATCTCCCAGAACTTCCTGTCCAGCATC
AACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGGGGGAGACGCGACAGCTGGTGAAGGACGGCTTCCTGGTGGAAGTG
TCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATGTCCTACTGTGTGCCAAGCTGAAGAAGACCTCTGCAGGGAAGCAC
CAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGTTTCCATCCCCCGAGGAGTCTGAGGCCAGCCCCCAGGTGCACCCC
TTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCCTCAAGAGTGAAATCCAGAAGGAGAAAGCCAACAAAGGCCAGAGC
CGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCCTGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAAT
CGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGAGGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGAT
CTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAGGATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACC
AGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTCATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAAC
CTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCAAAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGG
GATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAG
GACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCCAGGTTATTGCAGCTGACTGCAAAAGGGTCACAGTGCTGAAGTAT
TTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAGTATGTGTCAGTGGCACCCGTCCCAGACACCATG
GGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTGGTGATTGAAGACTTTGAGGAAGATTCAGAGGCT
GAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTGGCCAGGAAGATAGCTGAGCAGCAGCGTCGCCAG
GAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAAATCAGACCTTTGTTCCTCGTACCAGACACCAAC
GGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATCCTGGTGGTGCCCCTCATCGTGATCAATGAGCTG
GACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTGGTACAAGAGAAGGCCCGCAAGTCCATCGAGTTC
CTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGCAATGAACTCGAATCCATCGCCTTCCGCAGTGAG
GACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCACTACTGCAAAGACAAGGCTAAGGACTTCATGCCC
GCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGACCGGAACCTGCGTGTGAAGGCGCTCACAAGGAAT
GTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGGGCTGAGGGAGCCACACTGGGGCCCCCCCCCCGTGGAACCGTTCC
TGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTGCC

>561_561_7_ABR-SMG6_ABR_chr17_953289_ENST00000302538_SMG6_chr17_1989195_ENST00000536871_length(amino acids)=897AA_BP=597
MEPLSHRGLPRLSWIDTLYSNFSYGTDEYDGEGNEEQKGPPEGSETMPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLE
MRKLVLSGFLASEEIYINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQ
LGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDA
LRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSP
EESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEW
REAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKT
RVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGK
YVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELE
IRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRG
NELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG

--------------------------------------------------------------
>561_561_8_ABR-SMG6_ABR_chr17_953289_ENST00000302538_SMG6_chr17_1989195_ENST00000544865_length(transcript)=4494nt_BP=1938nt
GCCCCGCGCTCCTCCCGGGGACCTGGTTCCCGGCCTCCTCGCCCCTCCGCGCTCGCAACTTCGGCCTCCCCCGGCTCCCGCCCGCTCTCC
CTCCTTTGTTGCGCGATGAGGGTCGGGTTTCGGATCTGACCGAGCCGCCGCCGCGGGATGGAGCCGCTCAGCCACCGGGGCCTGCCGCGC
CTGTCCTGGATCGACACCCTCTACAGCAACTTCAGCTACGGGACGGACGAGTACGACGGAGAGGGGAATGAGGAGCAGAAGGGGCCCCCG
GAGGGCTCAGAGACCATGCCGTACATCGATGAGTCGCCCACCATGTCCCCGCAGCTCAGCGCCCGCAGCCAGGGCGGGGGGGATGGCGTC
TCCCCGACTCCACCTGAGGGACTGGCTCCTGGGGTGGAAGCAGGGAAAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCC
AGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCATGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTC
ACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCTATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTG
CAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGCTGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTAT
AAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACCAGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAG
GACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGCTCTGCTCTACAAGCCCATTGACCGGGTCACTCGGAGCACCCTAGTCCTACAC
GACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGCTGCAGGATGCCCTCCGCATCTCCCAGAACTTCCTGTCCAGCATC
AACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGGGGGAGACGCGACAGCTGGTGAAGGACGGCTTCCTGGTGGAAGTG
TCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATGTCCTACTGTGTGCCAAGCTGAAGAAGACCTCTGCAGGGAAGCAC
CAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGTTTCCATCCCCCGAGGAGTCTGAGGCCAGCCCCCAGGTGCACCCC
TTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCCTCAAGAGTGAAATCCAGAAGGAGAAAGCCAACAAAGGCCAGAGC
CGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCCTGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAAT
CGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGAGGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGAT
CTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAGGATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACC
AGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTCATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAAC
CTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCAAAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGG
GATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAG
GACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCCAGGTTATTGCAGCTGACTGCAAAAGGGTCACAGTGCTGAAGTAT
TTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAGTATGTGTCAGTGGCACCCGTCCCAGACACCATG
GGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTGGTGATTGAAGACTTTGAGGAAGATTCAGAGGCT
GAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTGGCCAGGAAGATAGCTGAGCAGCAGCGTCGCCAG
GAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAAATCAGACCTTTGTTCCTCGTACCAGACACCAAC
GGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATCCTGGTGGTGCCCCTCATCGTGATCAATGAGCTG
GACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTGGTACAAGAGAAGGCCCGCAAGTCCATCGAGTTC
CTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGCAATGAACTCGAATCCATCGCCTTCCGCAGTGAG
GACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCACTACTGCAAAGACAAGGCTAAGGACTTCATGCCC
GCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGACCGGAACCTGCGTGTGAAGGCGCTCACAAGGAAT
GTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGGGCTGAGGGAGCCACACTGGGGCCCCCCCCCCGTGGAACCGTTCC
TGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTGCCTGAGCCACCAATCCACCCAGACAATAAACCATCCTCTTCCAA
CCCACGCCACGGCCATGCTGTGGGGGACCTGCTCCTCACAGAGCCCCTCCCAAGGATCGGGCGGAAGCTGCTGGGACCCTCCTGGGCTGC
CAGGATTTAGCAGGGAGGTGGCTGGCTACAGCAACAGCAGCTGGGCAAGCCAGATAGGCCGCCCATGCTCTCAGCCTTTCTCCCTCCCCC
GTCTCATTCCAAGGCTGAGGGAGGGCCTTCTCGCCTGGGGACGCAGCCACTTTCTCCAGTGGAGACAGGGCAGGGGTTCTGAGTTTCCGT
CAGATGCAGTGAAATCACAGTTCCCTTTCATCTTCAGAACCTCTGTCGTGAATGTGTTCAAGAGGCTTTGGTTAAGTCAGGAAGAAGTGC
CCAGGGTGTGTGTCCCCAGTCTCCCTGAGGCCTGGACTCGCCCATGAACCCAAGTCGGCTTCTAGACAGCATGTCCCTAACAGCAGCCCT
GGGCCCCCACCTCTTCTACCATCCACCCCAGACTTACCACACACCCTTCCTGCTGCTCCTCTTCCTGCCCTTATCAACCTGGGTCCCTCA
CACTTCGCCAGTTGCGTCCCCGTGGACAGTCATGAGTCTAGAGGAAAGGGGCATCTGGTCTCAGGCCCGTGCTCTCGGGTGGCCTCCACC
TGCTCCCTCTCTCCTCACTGGCCTTTCTTTCCGTCTAGCTTCCTCTTCAGGAAATGTCCTGACTCCCCTCAGCTCCCCCTTCACCCCTCC
TTGCCCGCCTACCCTCCCTCCAGAATAGCCCCTCACCCTTCTTCCCCTTCTAGTTGATCCTTTTCACCTCCCTGATCCCCTTCATTTCTT
CACCGCGGTTCCTCGTCATAGGGGTTCTCACTCTGAACTTTCCCTCTCTACTACCCATGGCAGGAACCTAGTACAGGTCTCCCACCCAGG
GCCTTCCACCCTCGGCTCCTGTGCTGGGAGAAACTTCCAGGCGTGGACAGCCCAGCCTGAGGCATTCCAGTGCTGGGGCACCGTCGCCTA
ACCTGGTTTCTAGCTTTGCCCTCACTCCCCGGAAAAACTGACACTGACACAGGGGCCCTTTCCTTGCCCCTTTAGCTGGTACCTCAGTGG
GGAGGCTTCCTTACCAAGAATGAGTTCCTGAAACCCAGGGCCAGAGACAAGGACAACTTAGGGGAAGACGGGGTTTTCGGTGGAGCCAGG
GGCAAATCTTAATGGGACCAGTGGGGGATACCCCAGAGCCCATGGCCTGACTGCACAGCCTGCCTGGAGGATGGGTGCGCAGCTCTGCCC
TCCCTGAGGCCCAGGACTATGCCAGAAGCGATGGGGTACCGTGTAGGGGAGCCAAGGCCAGTAGTTTGGGGGTAGGAGTCCCCTAGAGTC
TCAGAAGACTGGGCTCTTTGGAGTACAGGGTCCCCGGCCTCTCCTTTAAGATTCTCTCCCCAGCTGGAAGGCCGATGACTGGGTGGTCGG
GAGGGAGACCCAGCTCTCCTTTCTGTCCCGTTTGCAGCACTGGTTTTGTTTCCTTAATAAATTTTTAGTTATGAAACATACCTG

>561_561_8_ABR-SMG6_ABR_chr17_953289_ENST00000302538_SMG6_chr17_1989195_ENST00000544865_length(amino acids)=897AA_BP=597
MEPLSHRGLPRLSWIDTLYSNFSYGTDEYDGEGNEEQKGPPEGSETMPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLE
MRKLVLSGFLASEEIYINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQ
LGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDA
LRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSP
EESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEW
REAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKT
RVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGK
YVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELE
IRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRG
NELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG

--------------------------------------------------------------
>561_561_9_ABR-SMG6_ABR_chr17_953289_ENST00000536794_SMG6_chr17_1989195_ENST00000263073_length(transcript)=3976nt_BP=1424nt
AGCCTCGTGCCCAGGCAGCCAGCCAGCTACAAACGTGCTCCTCTTTAGGATGCCAGCAGGCTGCTGGCTCCCTCCCTCCCTACCCCTCCT
CCCCTTCCCCTTCCCTCCTCTCCTCGCCACGCGCCTCCCTCCCCTCCCCCTTGCTGGAAGAGCACTCCGGAGCGGCTGCCCGATGCTGGA
GTCCGTGCGGCAGCATCAGCAAGGTGGCTGAGTGGCCGGGCTGCTGGTGGGCGCCGGGGAGCCTGGAGCGATGGCTGCACGCTCCCGCCG
CGGGGACAGAGGCTGCCATGGAGATTCTCCTCATTATTCGCTTCTGCTGTAACTGCACCTATGCTCTGCTCTACAAGCCCATTGACCGGG
TCACTCGGAGCACCCTAGTCCTACACGACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGCTGCAGGATGCCCTCCGCA
TCTCCCAGAACTTCCTGTCCAGCATCAACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGGGGGAGACGCGACAGCTGG
TGAAGGACGGCTTCCTGGTGGAAGTGTCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATGTCCTACTGTGTGCCAAGC
TGAAGAAGACCTCTGCAGGGAAGCACCAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGTTTCCATCCCCCGAGGAGT
CTGAGGCCAGCCCCCAGGTGCACCCCTTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCCTCAAGAGTGAAATCCAGA
AGGAGAAAGCCAACAAAGGCCAGAGCCGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCCTGCTGCTGCTCAACTCCC
CCACAATCCCGTTCAGGATCCACAATCGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGAGGTCAGAGTGGAGAGAAG
CAATTCAGAAACTACAGAAGAAGGATCTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAGGATCCTGTTTCAAGCTTA
GGACTGTACACAACATTCCTGTCACCAGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTCATGTCATCGTCCACTCTG
CCAAGGGATTTAAGCAATCAGCCAACCTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCAAAGCCAAAACCAGGGTGT
TCCGGGACACAGCGGAGCCCAAGTGGGATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAGT
GCTATGACAAGACCAAGGTCAACAAGGACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCCAGGTTATTGCAGCTGACT
GCAAAAGGGTCACAGTGCTGAAGTATTTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAGTATGTGT
CAGTGGCACCCGTCCCAGACACCATGGGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTGGTGATTG
AAGACTTTGAGGAAGATTCAGAGGCTGAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTGGCCAGGA
AGATAGCTGAGCAGCAGCGTCGCCAGGAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAAATCAGAC
CTTTGTTCCTCGTACCAGACACCAACGGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATCCTGGTGG
TGCCCCTCATCGTGATCAATGAGCTGGACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTGGTACAAG
AGAAGGCCCGCAAGTCCATCGAGTTCCTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGCAATGAAC
TCGAATCCATCGCCTTCCGCAGTGAGGACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCACTACTGCA
AAGACAAGGCTAAGGACTTCATGCCCGCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGACCGGAACC
TGCGTGTGAAGGCGCTCACAAGGAATGTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGGGCTGAGGGAGCCACACTG
GGGCCCCCCCCCCGTGGAACCGTTCCTGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTGCCTGAGCCACCAATCCAC
CCAGACAATAAACCATCCTCTTCCAACCCACGCCACGGCCATGCTGTGGGGGACCTGCTCCTCACAGAGCCCCTCCCAAGGATCGGGCGG
AAGCTGCTGGGACCCTCCTGGGCTGCCAGGATTTAGCAGGGAGGTGGCTGGCTACAGCAACAGCAGCTGGGCAAGCCAGATAGGCCGCCC
ATGCTCTCAGCCTTTCTCCCTCCCCCGTCTCATTCCAAGGCTGAGGGAGGGCCTTCTCGCCTGGGGACGCAGCCACTTTCTCCAGTGGAG
ACAGGGCAGGGGTTCTGAGTTTCCGTCAGATGCAGTGAAATCACAGTTCCCTTTCATCTTCAGAACCTCTGTCGTGAATGTGTTCAAGAG
GCTTTGGTTAAGTCAGGAAGAAGTGCCCAGGGTGTGTGTCCCCAGTCTCCCTGAGGCCTGGACTCGCCCATGAACCCAAGTCGGCTTCTA
GACAGCATGTCCCTAACAGCAGCCCTGGGCCCCCACCTCTTCTACCATCCACCCCAGACTTACCACACACCCTTCCTGCTGCTCCTCTTC
CTGCCCTTATCAACCTGGGTCCCTCACACTTCGCCAGTTGCGTCCCCGTGGACAGTCATGAGTCTAGAGGAAAGGGGCATCTGGTCTCAG
GCCCGTGCTCTCGGGTGGCCTCCACCTGCTCCCTCTCTCCTCACTGGCCTTTCTTTCCGTCTAGCTTCCTCTTCAGGAAATGTCCTGACT
CCCCTCAGCTCCCCCTTCACCCCTCCTTGCCCGCCTACCCTCCCTCCAGAATAGCCCCTCACCCTTCTTCCCCTTCTAGTTGATCCTTTT
CACCTCCCTGATCCCCTTCATTTCTTCACCGCGGTTCCTCGTCATAGGGGTTCTCACTCTGAACTTTCCCTCTCTACTACCCATGGCAGG
AACCTAGTACAGGTCTCCCACCCAGGGCCTTCCACCCTCGGCTCCTGTGCTGGGAGAAACTTCCAGGCGTGGACAGCCCAGCCTGAGGCA
TTCCAGTGCTGGGGCACCGTCGCCTAACCTGGTTTCTAGCTTTGCCCTCACTCCCCGGAAAAACTGACACTGACACAGGGGCCCTTTCCT
TGCCCCTTTAGCTGGTACCTCAGTGGGGAGGCTTCCTTACCAAGAATGAGTTCCTGAAACCCAGGGCCAGAGACAAGGACAACTTAGGGG
AAGACGGGGTTTTCGGTGGAGCCAGGGGCAAATCTTAATGGGACCAGTGGGGGATACCCCAGAGCCCATGGCCTGACTGCACAGCCTGCC
TGGAGGATGGGTGCGCAGCTCTGCCCTCCCTGAGGCCCAGGACTATGCCAGAAGCGATGGGGTACCGTGTAGGGGAGCCAAGGCCAGTAG
TTTGGGGGTAGGAGTCCCCTAGAGTCTCAGAAGACTGGGCTCTTTGGAGTACAGGGTCCCCGGCCTCTCCTTTAAGATTCTCTCCCCAGC
TGGAAGGCCGATGACTGGGTGGTCGGGAGGGAGACCCAGCTCTCCTTTCTGTCCCGTTTGCAGCACTGGTTTTGTTTCCTTAATAAATTT
TTAGTTATGAAACATA

>561_561_9_ABR-SMG6_ABR_chr17_953289_ENST00000536794_SMG6_chr17_1989195_ENST00000263073_length(amino acids)=728AA_BP=428
MLEEHSGAAARCWSPCGSISKVAEWPGCWWAPGSLERWLHAPAAGTEAAMEILLIIRFCCNCTYALLYKPIDRVTRSTLVLHDLLKHTPV
DHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWY
IPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLF
LLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVD
SFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQVIAADCKRVTVLKYFLEALCGQ
EEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLE
DHSQMRQMELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESR
DSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPA
FLTWAQVG

--------------------------------------------------------------
>561_561_10_ABR-SMG6_ABR_chr17_953289_ENST00000536794_SMG6_chr17_1989195_ENST00000354901_length(transcript)=3969nt_BP=1424nt
AGCCTCGTGCCCAGGCAGCCAGCCAGCTACAAACGTGCTCCTCTTTAGGATGCCAGCAGGCTGCTGGCTCCCTCCCTCCCTACCCCTCCT
CCCCTTCCCCTTCCCTCCTCTCCTCGCCACGCGCCTCCCTCCCCTCCCCCTTGCTGGAAGAGCACTCCGGAGCGGCTGCCCGATGCTGGA
GTCCGTGCGGCAGCATCAGCAAGGTGGCTGAGTGGCCGGGCTGCTGGTGGGCGCCGGGGAGCCTGGAGCGATGGCTGCACGCTCCCGCCG
CGGGGACAGAGGCTGCCATGGAGATTCTCCTCATTATTCGCTTCTGCTGTAACTGCACCTATGCTCTGCTCTACAAGCCCATTGACCGGG
TCACTCGGAGCACCCTAGTCCTACACGACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGCTGCAGGATGCCCTCCGCA
TCTCCCAGAACTTCCTGTCCAGCATCAACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGGGGGAGACGCGACAGCTGG
TGAAGGACGGCTTCCTGGTGGAAGTGTCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATGTCCTACTGTGTGCCAAGC
TGAAGAAGACCTCTGCAGGGAAGCACCAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGTTTCCATCCCCCGAGGAGT
CTGAGGCCAGCCCCCAGGTGCACCCCTTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCCTCAAGAGTGAAATCCAGA
AGGAGAAAGCCAACAAAGGCCAGAGCCGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCCTGCTGCTGCTCAACTCCC
CCACAATCCCGTTCAGGATCCACAATCGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGAGGTCAGAGTGGAGAGAAG
CAATTCAGAAACTACAGAAGAAGGATCTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAGGATCCTGTTTCAAGCTTA
GGACTGTACACAACATTCCTGTCACCAGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTCATGTCATCGTCCACTCTG
CCAAGGGATTTAAGCAATCAGCCAACCTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCAAAGCCAAAACCAGGGTGT
TCCGGGACACAGCGGAGCCCAAGTGGGATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAGT
GCTATGACAAGACCAAGGTCAACAAGGACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCCAGGTTATTGCAGCTGACT
GCAAAAGGGTCACAGTGCTGAAGTATTTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAGTATGTGT
CAGTGGCACCCGTCCCAGACACCATGGGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTGGTGATTG
AAGACTTTGAGGAAGATTCAGAGGCTGAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTGGCCAGGA
AGATAGCTGAGCAGCAGCGTCGCCAGGAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAAATCAGAC
CTTTGTTCCTCGTACCAGACACCAACGGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATCCTGGTGG
TGCCCCTCATCGTGATCAATGAGCTGGACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTGGTACAAG
AGAAGGCCCGCAAGTCCATCGAGTTCCTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGCAATGAAC
TCGAATCCATCGCCTTCCGCAGTGAGGACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCACTACTGCA
AAGACAAGGCTAAGGACTTCATGCCCGCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGACCGGAACC
TGCGTGTGAAGGCGCTCACAAGGAATGTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGGGCTGAGGGAGCCACACTG
GGGCCCCCCCCCCGTGGAACCGTTCCTGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTGCCTGAGCCACCAATCCAC
CCAGACAATAAACCATCCTCTTCCAACCCACGCCACGGCCATGCTGTGGGGGACCTGCTCCTCACAGAGCCCCTCCCAAGGATCGGGCGG
AAGCTGCTGGGACCCTCCTGGGCTGCCAGGATTTAGCAGGGAGGTGGCTGGCTACAGCAACAGCAGCTGGGCAAGCCAGATAGGCCGCCC
ATGCTCTCAGCCTTTCTCCCTCCCCCGTCTCATTCCAAGGCTGAGGGAGGGCCTTCTCGCCTGGGGACGCAGCCACTTTCTCCAGTGGAG
ACAGGGCAGGGGTTCTGAGTTTCCGTCAGATGCAGTGAAATCACAGTTCCCTTTCATCTTCAGAACCTCTGTCGTGAATGTGTTCAAGAG
GCTTTGGTTAAGTCAGGAAGAAGTGCCCAGGGTGTGTGTCCCCAGTCTCCCTGAGGCCTGGACTCGCCCATGAACCCAAGTCGGCTTCTA
GACAGCATGTCCCTAACAGCAGCCCTGGGCCCCCACCTCTTCTACCATCCACCCCAGACTTACCACACACCCTTCCTGCTGCTCCTCTTC
CTGCCCTTATCAACCTGGGTCCCTCACACTTCGCCAGTTGCGTCCCCGTGGACAGTCATGAGTCTAGAGGAAAGGGGCATCTGGTCTCAG
GCCCGTGCTCTCGGGTGGCCTCCACCTGCTCCCTCTCTCCTCACTGGCCTTTCTTTCCGTCTAGCTTCCTCTTCAGGAAATGTCCTGACT
CCCCTCAGCTCCCCCTTCACCCCTCCTTGCCCGCCTACCCTCCCTCCAGAATAGCCCCTCACCCTTCTTCCCCTTCTAGTTGATCCTTTT
CACCTCCCTGATCCCCTTCATTTCTTCACCGCGGTTCCTCGTCATAGGGGTTCTCACTCTGAACTTTCCCTCTCTACTACCCATGGCAGG
AACCTAGTACAGGTCTCCCACCCAGGGCCTTCCACCCTCGGCTCCTGTGCTGGGAGAAACTTCCAGGCGTGGACAGCCCAGCCTGAGGCA
TTCCAGTGCTGGGGCACCGTCGCCTAACCTGGTTTCTAGCTTTGCCCTCACTCCCCGGAAAAACTGACACTGACACAGGGGCCCTTTCCT
TGCCCCTTTAGCTGGTACCTCAGTGGGGAGGCTTCCTTACCAAGAATGAGTTCCTGAAACCCAGGGCCAGAGACAAGGACAACTTAGGGG
AAGACGGGGTTTTCGGTGGAGCCAGGGGCAAATCTTAATGGGACCAGTGGGGGATACCCCAGAGCCCATGGCCTGACTGCACAGCCTGCC
TGGAGGATGGGTGCGCAGCTCTGCCCTCCCTGAGGCCCAGGACTATGCCAGAAGCGATGGGGTACCGTGTAGGGGAGCCAAGGCCAGTAG
TTTGGGGGTAGGAGTCCCCTAGAGTCTCAGAAGACTGGGCTCTTTGGAGTACAGGGTCCCCGGCCTCTCCTTTAAGATTCTCTCCCCAGC
TGGAAGGCCGATGACTGGGTGGTCGGGAGGGAGACCCAGCTCTCCTTTCTGTCCCGTTTGCAGCACTGGTTTTGTTTCCTTAATAAATTT
TTAGTTATG

>561_561_10_ABR-SMG6_ABR_chr17_953289_ENST00000536794_SMG6_chr17_1989195_ENST00000354901_length(amino acids)=728AA_BP=428
MLEEHSGAAARCWSPCGSISKVAEWPGCWWAPGSLERWLHAPAAGTEAAMEILLIIRFCCNCTYALLYKPIDRVTRSTLVLHDLLKHTPV
DHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWY
IPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLF
LLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVD
SFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQVIAADCKRVTVLKYFLEALCGQ
EEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLE
DHSQMRQMELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESR
DSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPA
FLTWAQVG

--------------------------------------------------------------
>561_561_11_ABR-SMG6_ABR_chr17_953289_ENST00000536794_SMG6_chr17_1989195_ENST00000536871_length(transcript)=2414nt_BP=1424nt
AGCCTCGTGCCCAGGCAGCCAGCCAGCTACAAACGTGCTCCTCTTTAGGATGCCAGCAGGCTGCTGGCTCCCTCCCTCCCTACCCCTCCT
CCCCTTCCCCTTCCCTCCTCTCCTCGCCACGCGCCTCCCTCCCCTCCCCCTTGCTGGAAGAGCACTCCGGAGCGGCTGCCCGATGCTGGA
GTCCGTGCGGCAGCATCAGCAAGGTGGCTGAGTGGCCGGGCTGCTGGTGGGCGCCGGGGAGCCTGGAGCGATGGCTGCACGCTCCCGCCG
CGGGGACAGAGGCTGCCATGGAGATTCTCCTCATTATTCGCTTCTGCTGTAACTGCACCTATGCTCTGCTCTACAAGCCCATTGACCGGG
TCACTCGGAGCACCCTAGTCCTACACGACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGCTGCAGGATGCCCTCCGCA
TCTCCCAGAACTTCCTGTCCAGCATCAACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGGGGGAGACGCGACAGCTGG
TGAAGGACGGCTTCCTGGTGGAAGTGTCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATGTCCTACTGTGTGCCAAGC
TGAAGAAGACCTCTGCAGGGAAGCACCAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGTTTCCATCCCCCGAGGAGT
CTGAGGCCAGCCCCCAGGTGCACCCCTTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCCTCAAGAGTGAAATCCAGA
AGGAGAAAGCCAACAAAGGCCAGAGCCGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCCTGCTGCTGCTCAACTCCC
CCACAATCCCGTTCAGGATCCACAATCGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGAGGTCAGAGTGGAGAGAAG
CAATTCAGAAACTACAGAAGAAGGATCTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAGGATCCTGTTTCAAGCTTA
GGACTGTACACAACATTCCTGTCACCAGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTCATGTCATCGTCCACTCTG
CCAAGGGATTTAAGCAATCAGCCAACCTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCAAAGCCAAAACCAGGGTGT
TCCGGGACACAGCGGAGCCCAAGTGGGATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAGT
GCTATGACAAGACCAAGGTCAACAAGGACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCCAGGTTATTGCAGCTGACT
GCAAAAGGGTCACAGTGCTGAAGTATTTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAGTATGTGT
CAGTGGCACCCGTCCCAGACACCATGGGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTGGTGATTG
AAGACTTTGAGGAAGATTCAGAGGCTGAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTGGCCAGGA
AGATAGCTGAGCAGCAGCGTCGCCAGGAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAAATCAGAC
CTTTGTTCCTCGTACCAGACACCAACGGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATCCTGGTGG
TGCCCCTCATCGTGATCAATGAGCTGGACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTGGTACAAG
AGAAGGCCCGCAAGTCCATCGAGTTCCTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGCAATGAAC
TCGAATCCATCGCCTTCCGCAGTGAGGACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCACTACTGCA
AAGACAAGGCTAAGGACTTCATGCCCGCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGACCGGAACC
TGCGTGTGAAGGCGCTCACAAGGAATGTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGGGCTGAGGGAGCCACACTG
GGGCCCCCCCCCCGTGGAACCGTTCCTGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTGCC

>561_561_11_ABR-SMG6_ABR_chr17_953289_ENST00000536794_SMG6_chr17_1989195_ENST00000536871_length(amino acids)=728AA_BP=428
MLEEHSGAAARCWSPCGSISKVAEWPGCWWAPGSLERWLHAPAAGTEAAMEILLIIRFCCNCTYALLYKPIDRVTRSTLVLHDLLKHTPV
DHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWY
IPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLF
LLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVD
SFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQVIAADCKRVTVLKYFLEALCGQ
EEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLE
DHSQMRQMELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESR
DSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPA
FLTWAQVG

--------------------------------------------------------------
>561_561_12_ABR-SMG6_ABR_chr17_953289_ENST00000536794_SMG6_chr17_1989195_ENST00000544865_length(transcript)=3980nt_BP=1424nt
AGCCTCGTGCCCAGGCAGCCAGCCAGCTACAAACGTGCTCCTCTTTAGGATGCCAGCAGGCTGCTGGCTCCCTCCCTCCCTACCCCTCCT
CCCCTTCCCCTTCCCTCCTCTCCTCGCCACGCGCCTCCCTCCCCTCCCCCTTGCTGGAAGAGCACTCCGGAGCGGCTGCCCGATGCTGGA
GTCCGTGCGGCAGCATCAGCAAGGTGGCTGAGTGGCCGGGCTGCTGGTGGGCGCCGGGGAGCCTGGAGCGATGGCTGCACGCTCCCGCCG
CGGGGACAGAGGCTGCCATGGAGATTCTCCTCATTATTCGCTTCTGCTGTAACTGCACCTATGCTCTGCTCTACAAGCCCATTGACCGGG
TCACTCGGAGCACCCTAGTCCTACACGACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGCTGCAGGATGCCCTCCGCA
TCTCCCAGAACTTCCTGTCCAGCATCAACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGGGGGAGACGCGACAGCTGG
TGAAGGACGGCTTCCTGGTGGAAGTGTCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATGTCCTACTGTGTGCCAAGC
TGAAGAAGACCTCTGCAGGGAAGCACCAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGTTTCCATCCCCCGAGGAGT
CTGAGGCCAGCCCCCAGGTGCACCCCTTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCCTCAAGAGTGAAATCCAGA
AGGAGAAAGCCAACAAAGGCCAGAGCCGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCCTGCTGCTGCTCAACTCCC
CCACAATCCCGTTCAGGATCCACAATCGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGAGGTCAGAGTGGAGAGAAG
CAATTCAGAAACTACAGAAGAAGGATCTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAGGATCCTGTTTCAAGCTTA
GGACTGTACACAACATTCCTGTCACCAGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTCATGTCATCGTCCACTCTG
CCAAGGGATTTAAGCAATCAGCCAACCTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCAAAGCCAAAACCAGGGTGT
TCCGGGACACAGCGGAGCCCAAGTGGGATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAGT
GCTATGACAAGACCAAGGTCAACAAGGACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCCAGGTTATTGCAGCTGACT
GCAAAAGGGTCACAGTGCTGAAGTATTTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAGTATGTGT
CAGTGGCACCCGTCCCAGACACCATGGGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTGGTGATTG
AAGACTTTGAGGAAGATTCAGAGGCTGAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTGGCCAGGA
AGATAGCTGAGCAGCAGCGTCGCCAGGAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAAATCAGAC
CTTTGTTCCTCGTACCAGACACCAACGGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATCCTGGTGG
TGCCCCTCATCGTGATCAATGAGCTGGACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTGGTACAAG
AGAAGGCCCGCAAGTCCATCGAGTTCCTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGCAATGAAC
TCGAATCCATCGCCTTCCGCAGTGAGGACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCACTACTGCA
AAGACAAGGCTAAGGACTTCATGCCCGCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGACCGGAACC
TGCGTGTGAAGGCGCTCACAAGGAATGTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGGGCTGAGGGAGCCACACTG
GGGCCCCCCCCCCGTGGAACCGTTCCTGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTGCCTGAGCCACCAATCCAC
CCAGACAATAAACCATCCTCTTCCAACCCACGCCACGGCCATGCTGTGGGGGACCTGCTCCTCACAGAGCCCCTCCCAAGGATCGGGCGG
AAGCTGCTGGGACCCTCCTGGGCTGCCAGGATTTAGCAGGGAGGTGGCTGGCTACAGCAACAGCAGCTGGGCAAGCCAGATAGGCCGCCC
ATGCTCTCAGCCTTTCTCCCTCCCCCGTCTCATTCCAAGGCTGAGGGAGGGCCTTCTCGCCTGGGGACGCAGCCACTTTCTCCAGTGGAG
ACAGGGCAGGGGTTCTGAGTTTCCGTCAGATGCAGTGAAATCACAGTTCCCTTTCATCTTCAGAACCTCTGTCGTGAATGTGTTCAAGAG
GCTTTGGTTAAGTCAGGAAGAAGTGCCCAGGGTGTGTGTCCCCAGTCTCCCTGAGGCCTGGACTCGCCCATGAACCCAAGTCGGCTTCTA
GACAGCATGTCCCTAACAGCAGCCCTGGGCCCCCACCTCTTCTACCATCCACCCCAGACTTACCACACACCCTTCCTGCTGCTCCTCTTC
CTGCCCTTATCAACCTGGGTCCCTCACACTTCGCCAGTTGCGTCCCCGTGGACAGTCATGAGTCTAGAGGAAAGGGGCATCTGGTCTCAG
GCCCGTGCTCTCGGGTGGCCTCCACCTGCTCCCTCTCTCCTCACTGGCCTTTCTTTCCGTCTAGCTTCCTCTTCAGGAAATGTCCTGACT
CCCCTCAGCTCCCCCTTCACCCCTCCTTGCCCGCCTACCCTCCCTCCAGAATAGCCCCTCACCCTTCTTCCCCTTCTAGTTGATCCTTTT
CACCTCCCTGATCCCCTTCATTTCTTCACCGCGGTTCCTCGTCATAGGGGTTCTCACTCTGAACTTTCCCTCTCTACTACCCATGGCAGG
AACCTAGTACAGGTCTCCCACCCAGGGCCTTCCACCCTCGGCTCCTGTGCTGGGAGAAACTTCCAGGCGTGGACAGCCCAGCCTGAGGCA
TTCCAGTGCTGGGGCACCGTCGCCTAACCTGGTTTCTAGCTTTGCCCTCACTCCCCGGAAAAACTGACACTGACACAGGGGCCCTTTCCT
TGCCCCTTTAGCTGGTACCTCAGTGGGGAGGCTTCCTTACCAAGAATGAGTTCCTGAAACCCAGGGCCAGAGACAAGGACAACTTAGGGG
AAGACGGGGTTTTCGGTGGAGCCAGGGGCAAATCTTAATGGGACCAGTGGGGGATACCCCAGAGCCCATGGCCTGACTGCACAGCCTGCC
TGGAGGATGGGTGCGCAGCTCTGCCCTCCCTGAGGCCCAGGACTATGCCAGAAGCGATGGGGTACCGTGTAGGGGAGCCAAGGCCAGTAG
TTTGGGGGTAGGAGTCCCCTAGAGTCTCAGAAGACTGGGCTCTTTGGAGTACAGGGTCCCCGGCCTCTCCTTTAAGATTCTCTCCCCAGC
TGGAAGGCCGATGACTGGGTGGTCGGGAGGGAGACCCAGCTCTCCTTTCTGTCCCGTTTGCAGCACTGGTTTTGTTTCCTTAATAAATTT
TTAGTTATGAAACATACCTG

>561_561_12_ABR-SMG6_ABR_chr17_953289_ENST00000536794_SMG6_chr17_1989195_ENST00000544865_length(amino acids)=728AA_BP=428
MLEEHSGAAARCWSPCGSISKVAEWPGCWWAPGSLERWLHAPAAGTEAAMEILLIIRFCCNCTYALLYKPIDRVTRSTLVLHDLLKHTPV
DHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWY
IPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLF
LLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVD
SFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQVIAADCKRVTVLKYFLEALCGQ
EEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLE
DHSQMRQMELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESR
DSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPA
FLTWAQVG

--------------------------------------------------------------
>561_561_13_ABR-SMG6_ABR_chr17_953289_ENST00000574437_SMG6_chr17_1989195_ENST00000263073_length(transcript)=4670nt_BP=2118nt
ATAAAAAGCAAAATGGTGACTCAGAGAGGAGAGTTGGAAGCGTCCTGCCTCTTGCTCCCACTGTTAATTTTTACACTTGGAATTAGGCAG
AAGGCAAAGAAAACAGCAGCTTGAAATACGCGGCTGACATGCTCTTCATCGGGTAGCAACAGCAGAGCCGCTCCTCCCCGCCTCCCAGCA
GCCCCGGAGCGGGCAGGGCCCGGTGCCTGCTGGCTCTCCCCCGCCCCTCACCAGGCCCAGGCCCCCGCACAGCCCCCGCCCGGGCCAGGC
GTGGATGGTGCGGCCGGGGCCATGGCTGCCGGGGGCCGCCGCCGGCGCCCACTACGCTACCAGTCCCTGGCAGCTCTGGTGGAGGATTCT
CAGTGGCCTTTCTTGTTCCTTGTCTCAGACTTCAGCTACGGGACGGACGAGTACGACGGAGAGGGGAATGAGGAGCAGAAGGGGCCCCCG
GAGGGCTCAGAGACCATGCCGTACATCGATGAGTCGCCCACCATGTCCCCGCAGCTCAGCGCCCGCAGCCAGGGCGGGGGGGATGGCGTC
TCCCCGACTCCACCTGAGGGACTGGCTCCTGGGGTGGAAGCAGGGAAAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCC
AGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCATGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTC
ACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCTATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTG
CAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGCTGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTAT
AAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACCAGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAG
GACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGCTCTGCTCTACAAGCCCATTGACCGGGTCACTCGGAGCACCCTAGTCCTACAC
GACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGCTGCAGGATGCCCTCCGCATCTCCCAGAACTTCCTGTCCAGCATC
AACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGGGGGAGACGCGACAGCTGGTGAAGGACGGCTTCCTGGTGGAAGTG
TCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATGTCCTACTGTGTGCCAAGCTGAAGAAGACCTCTGCAGGGAAGCAC
CAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGTTTCCATCCCCCGAGGAGTCTGAGGCCAGCCCCCAGGTGCACCCC
TTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCCTCAAGAGTGAAATCCAGAAGGAGAAAGCCAACAAAGGCCAGAGC
CGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCCTGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAAT
CGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGAGGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGAT
CTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAGGATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACC
AGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTCATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAAC
CTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCAAAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGG
GATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAG
GACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCCAGGTTATTGCAGCTGACTGCAAAAGGGTCACAGTGCTGAAGTAT
TTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAGTATGTGTCAGTGGCACCCGTCCCAGACACCATG
GGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTGGTGATTGAAGACTTTGAGGAAGATTCAGAGGCT
GAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTGGCCAGGAAGATAGCTGAGCAGCAGCGTCGCCAG
GAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAAATCAGACCTTTGTTCCTCGTACCAGACACCAAC
GGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATCCTGGTGGTGCCCCTCATCGTGATCAATGAGCTG
GACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTGGTACAAGAGAAGGCCCGCAAGTCCATCGAGTTC
CTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGCAATGAACTCGAATCCATCGCCTTCCGCAGTGAG
GACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCACTACTGCAAAGACAAGGCTAAGGACTTCATGCCC
GCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGACCGGAACCTGCGTGTGAAGGCGCTCACAAGGAAT
GTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGGGCTGAGGGAGCCACACTGGGGCCCCCCCCCCGTGGAACCGTTCC
TGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTGCCTGAGCCACCAATCCACCCAGACAATAAACCATCCTCTTCCAA
CCCACGCCACGGCCATGCTGTGGGGGACCTGCTCCTCACAGAGCCCCTCCCAAGGATCGGGCGGAAGCTGCTGGGACCCTCCTGGGCTGC
CAGGATTTAGCAGGGAGGTGGCTGGCTACAGCAACAGCAGCTGGGCAAGCCAGATAGGCCGCCCATGCTCTCAGCCTTTCTCCCTCCCCC
GTCTCATTCCAAGGCTGAGGGAGGGCCTTCTCGCCTGGGGACGCAGCCACTTTCTCCAGTGGAGACAGGGCAGGGGTTCTGAGTTTCCGT
CAGATGCAGTGAAATCACAGTTCCCTTTCATCTTCAGAACCTCTGTCGTGAATGTGTTCAAGAGGCTTTGGTTAAGTCAGGAAGAAGTGC
CCAGGGTGTGTGTCCCCAGTCTCCCTGAGGCCTGGACTCGCCCATGAACCCAAGTCGGCTTCTAGACAGCATGTCCCTAACAGCAGCCCT
GGGCCCCCACCTCTTCTACCATCCACCCCAGACTTACCACACACCCTTCCTGCTGCTCCTCTTCCTGCCCTTATCAACCTGGGTCCCTCA
CACTTCGCCAGTTGCGTCCCCGTGGACAGTCATGAGTCTAGAGGAAAGGGGCATCTGGTCTCAGGCCCGTGCTCTCGGGTGGCCTCCACC
TGCTCCCTCTCTCCTCACTGGCCTTTCTTTCCGTCTAGCTTCCTCTTCAGGAAATGTCCTGACTCCCCTCAGCTCCCCCTTCACCCCTCC
TTGCCCGCCTACCCTCCCTCCAGAATAGCCCCTCACCCTTCTTCCCCTTCTAGTTGATCCTTTTCACCTCCCTGATCCCCTTCATTTCTT
CACCGCGGTTCCTCGTCATAGGGGTTCTCACTCTGAACTTTCCCTCTCTACTACCCATGGCAGGAACCTAGTACAGGTCTCCCACCCAGG
GCCTTCCACCCTCGGCTCCTGTGCTGGGAGAAACTTCCAGGCGTGGACAGCCCAGCCTGAGGCATTCCAGTGCTGGGGCACCGTCGCCTA
ACCTGGTTTCTAGCTTTGCCCTCACTCCCCGGAAAAACTGACACTGACACAGGGGCCCTTTCCTTGCCCCTTTAGCTGGTACCTCAGTGG
GGAGGCTTCCTTACCAAGAATGAGTTCCTGAAACCCAGGGCCAGAGACAAGGACAACTTAGGGGAAGACGGGGTTTTCGGTGGAGCCAGG
GGCAAATCTTAATGGGACCAGTGGGGGATACCCCAGAGCCCATGGCCTGACTGCACAGCCTGCCTGGAGGATGGGTGCGCAGCTCTGCCC
TCCCTGAGGCCCAGGACTATGCCAGAAGCGATGGGGTACCGTGTAGGGGAGCCAAGGCCAGTAGTTTGGGGGTAGGAGTCCCCTAGAGTC
TCAGAAGACTGGGCTCTTTGGAGTACAGGGTCCCCGGCCTCTCCTTTAAGATTCTCTCCCCAGCTGGAAGGCCGATGACTGGGTGGTCGG
GAGGGAGACCCAGCTCTCCTTTCTGTCCCGTTTGCAGCACTGGTTTTGTTTCCTTAATAAATTTTTAGTTATGAAACATA

>561_561_13_ABR-SMG6_ABR_chr17_953289_ENST00000574437_SMG6_chr17_1989195_ENST00000263073_length(amino acids)=965AA_BP=665
MTCSSSGSNSRAAPPRLPAAPERAGPGACWLSPAPHQAQAPAQPPPGPGVDGAAGAMAAGGRRRRPLRYQSLAALVEDSQWPFLFLVSDF
SYGTDEYDGEGNEEQKGPPEGSETMPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIYINQLEA
LLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCS
QSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAV
TTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKM
KISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVEL
QVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGS
QSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTR
LEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLASLAR
LLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDD
LILSCCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG

--------------------------------------------------------------
>561_561_14_ABR-SMG6_ABR_chr17_953289_ENST00000574437_SMG6_chr17_1989195_ENST00000354901_length(transcript)=4663nt_BP=2118nt
ATAAAAAGCAAAATGGTGACTCAGAGAGGAGAGTTGGAAGCGTCCTGCCTCTTGCTCCCACTGTTAATTTTTACACTTGGAATTAGGCAG
AAGGCAAAGAAAACAGCAGCTTGAAATACGCGGCTGACATGCTCTTCATCGGGTAGCAACAGCAGAGCCGCTCCTCCCCGCCTCCCAGCA
GCCCCGGAGCGGGCAGGGCCCGGTGCCTGCTGGCTCTCCCCCGCCCCTCACCAGGCCCAGGCCCCCGCACAGCCCCCGCCCGGGCCAGGC
GTGGATGGTGCGGCCGGGGCCATGGCTGCCGGGGGCCGCCGCCGGCGCCCACTACGCTACCAGTCCCTGGCAGCTCTGGTGGAGGATTCT
CAGTGGCCTTTCTTGTTCCTTGTCTCAGACTTCAGCTACGGGACGGACGAGTACGACGGAGAGGGGAATGAGGAGCAGAAGGGGCCCCCG
GAGGGCTCAGAGACCATGCCGTACATCGATGAGTCGCCCACCATGTCCCCGCAGCTCAGCGCCCGCAGCCAGGGCGGGGGGGATGGCGTC
TCCCCGACTCCACCTGAGGGACTGGCTCCTGGGGTGGAAGCAGGGAAAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCC
AGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCATGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTC
ACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCTATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTG
CAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGCTGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTAT
AAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACCAGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAG
GACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGCTCTGCTCTACAAGCCCATTGACCGGGTCACTCGGAGCACCCTAGTCCTACAC
GACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGCTGCAGGATGCCCTCCGCATCTCCCAGAACTTCCTGTCCAGCATC
AACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGGGGGAGACGCGACAGCTGGTGAAGGACGGCTTCCTGGTGGAAGTG
TCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATGTCCTACTGTGTGCCAAGCTGAAGAAGACCTCTGCAGGGAAGCAC
CAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGTTTCCATCCCCCGAGGAGTCTGAGGCCAGCCCCCAGGTGCACCCC
TTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCCTCAAGAGTGAAATCCAGAAGGAGAAAGCCAACAAAGGCCAGAGC
CGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCCTGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAAT
CGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGAGGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGAT
CTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAGGATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACC
AGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTCATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAAC
CTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCAAAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGG
GATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAG
GACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCCAGGTTATTGCAGCTGACTGCAAAAGGGTCACAGTGCTGAAGTAT
TTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAGTATGTGTCAGTGGCACCCGTCCCAGACACCATG
GGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTGGTGATTGAAGACTTTGAGGAAGATTCAGAGGCT
GAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTGGCCAGGAAGATAGCTGAGCAGCAGCGTCGCCAG
GAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAAATCAGACCTTTGTTCCTCGTACCAGACACCAAC
GGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATCCTGGTGGTGCCCCTCATCGTGATCAATGAGCTG
GACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTGGTACAAGAGAAGGCCCGCAAGTCCATCGAGTTC
CTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGCAATGAACTCGAATCCATCGCCTTCCGCAGTGAG
GACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCACTACTGCAAAGACAAGGCTAAGGACTTCATGCCC
GCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGACCGGAACCTGCGTGTGAAGGCGCTCACAAGGAAT
GTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGGGCTGAGGGAGCCACACTGGGGCCCCCCCCCCGTGGAACCGTTCC
TGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTGCCTGAGCCACCAATCCACCCAGACAATAAACCATCCTCTTCCAA
CCCACGCCACGGCCATGCTGTGGGGGACCTGCTCCTCACAGAGCCCCTCCCAAGGATCGGGCGGAAGCTGCTGGGACCCTCCTGGGCTGC
CAGGATTTAGCAGGGAGGTGGCTGGCTACAGCAACAGCAGCTGGGCAAGCCAGATAGGCCGCCCATGCTCTCAGCCTTTCTCCCTCCCCC
GTCTCATTCCAAGGCTGAGGGAGGGCCTTCTCGCCTGGGGACGCAGCCACTTTCTCCAGTGGAGACAGGGCAGGGGTTCTGAGTTTCCGT
CAGATGCAGTGAAATCACAGTTCCCTTTCATCTTCAGAACCTCTGTCGTGAATGTGTTCAAGAGGCTTTGGTTAAGTCAGGAAGAAGTGC
CCAGGGTGTGTGTCCCCAGTCTCCCTGAGGCCTGGACTCGCCCATGAACCCAAGTCGGCTTCTAGACAGCATGTCCCTAACAGCAGCCCT
GGGCCCCCACCTCTTCTACCATCCACCCCAGACTTACCACACACCCTTCCTGCTGCTCCTCTTCCTGCCCTTATCAACCTGGGTCCCTCA
CACTTCGCCAGTTGCGTCCCCGTGGACAGTCATGAGTCTAGAGGAAAGGGGCATCTGGTCTCAGGCCCGTGCTCTCGGGTGGCCTCCACC
TGCTCCCTCTCTCCTCACTGGCCTTTCTTTCCGTCTAGCTTCCTCTTCAGGAAATGTCCTGACTCCCCTCAGCTCCCCCTTCACCCCTCC
TTGCCCGCCTACCCTCCCTCCAGAATAGCCCCTCACCCTTCTTCCCCTTCTAGTTGATCCTTTTCACCTCCCTGATCCCCTTCATTTCTT
CACCGCGGTTCCTCGTCATAGGGGTTCTCACTCTGAACTTTCCCTCTCTACTACCCATGGCAGGAACCTAGTACAGGTCTCCCACCCAGG
GCCTTCCACCCTCGGCTCCTGTGCTGGGAGAAACTTCCAGGCGTGGACAGCCCAGCCTGAGGCATTCCAGTGCTGGGGCACCGTCGCCTA
ACCTGGTTTCTAGCTTTGCCCTCACTCCCCGGAAAAACTGACACTGACACAGGGGCCCTTTCCTTGCCCCTTTAGCTGGTACCTCAGTGG
GGAGGCTTCCTTACCAAGAATGAGTTCCTGAAACCCAGGGCCAGAGACAAGGACAACTTAGGGGAAGACGGGGTTTTCGGTGGAGCCAGG
GGCAAATCTTAATGGGACCAGTGGGGGATACCCCAGAGCCCATGGCCTGACTGCACAGCCTGCCTGGAGGATGGGTGCGCAGCTCTGCCC
TCCCTGAGGCCCAGGACTATGCCAGAAGCGATGGGGTACCGTGTAGGGGAGCCAAGGCCAGTAGTTTGGGGGTAGGAGTCCCCTAGAGTC
TCAGAAGACTGGGCTCTTTGGAGTACAGGGTCCCCGGCCTCTCCTTTAAGATTCTCTCCCCAGCTGGAAGGCCGATGACTGGGTGGTCGG
GAGGGAGACCCAGCTCTCCTTTCTGTCCCGTTTGCAGCACTGGTTTTGTTTCCTTAATAAATTTTTAGTTATG

>561_561_14_ABR-SMG6_ABR_chr17_953289_ENST00000574437_SMG6_chr17_1989195_ENST00000354901_length(amino acids)=965AA_BP=665
MTCSSSGSNSRAAPPRLPAAPERAGPGACWLSPAPHQAQAPAQPPPGPGVDGAAGAMAAGGRRRRPLRYQSLAALVEDSQWPFLFLVSDF
SYGTDEYDGEGNEEQKGPPEGSETMPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIYINQLEA
LLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCS
QSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAV
TTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKM
KISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVEL
QVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGS
QSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTR
LEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLASLAR
LLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDD
LILSCCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG

--------------------------------------------------------------
>561_561_15_ABR-SMG6_ABR_chr17_953289_ENST00000574437_SMG6_chr17_1989195_ENST00000536871_length(transcript)=3108nt_BP=2118nt
ATAAAAAGCAAAATGGTGACTCAGAGAGGAGAGTTGGAAGCGTCCTGCCTCTTGCTCCCACTGTTAATTTTTACACTTGGAATTAGGCAG
AAGGCAAAGAAAACAGCAGCTTGAAATACGCGGCTGACATGCTCTTCATCGGGTAGCAACAGCAGAGCCGCTCCTCCCCGCCTCCCAGCA
GCCCCGGAGCGGGCAGGGCCCGGTGCCTGCTGGCTCTCCCCCGCCCCTCACCAGGCCCAGGCCCCCGCACAGCCCCCGCCCGGGCCAGGC
GTGGATGGTGCGGCCGGGGCCATGGCTGCCGGGGGCCGCCGCCGGCGCCCACTACGCTACCAGTCCCTGGCAGCTCTGGTGGAGGATTCT
CAGTGGCCTTTCTTGTTCCTTGTCTCAGACTTCAGCTACGGGACGGACGAGTACGACGGAGAGGGGAATGAGGAGCAGAAGGGGCCCCCG
GAGGGCTCAGAGACCATGCCGTACATCGATGAGTCGCCCACCATGTCCCCGCAGCTCAGCGCCCGCAGCCAGGGCGGGGGGGATGGCGTC
TCCCCGACTCCACCTGAGGGACTGGCTCCTGGGGTGGAAGCAGGGAAAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCC
AGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCATGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTC
ACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCTATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTG
CAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGCTGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTAT
AAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACCAGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAG
GACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGCTCTGCTCTACAAGCCCATTGACCGGGTCACTCGGAGCACCCTAGTCCTACAC
GACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGCTGCAGGATGCCCTCCGCATCTCCCAGAACTTCCTGTCCAGCATC
AACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGGGGGAGACGCGACAGCTGGTGAAGGACGGCTTCCTGGTGGAAGTG
TCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATGTCCTACTGTGTGCCAAGCTGAAGAAGACCTCTGCAGGGAAGCAC
CAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGTTTCCATCCCCCGAGGAGTCTGAGGCCAGCCCCCAGGTGCACCCC
TTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCCTCAAGAGTGAAATCCAGAAGGAGAAAGCCAACAAAGGCCAGAGC
CGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCCTGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAAT
CGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGAGGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGAT
CTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAGGATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACC
AGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTCATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAAC
CTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCAAAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGG
GATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAG
GACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCCAGGTTATTGCAGCTGACTGCAAAAGGGTCACAGTGCTGAAGTAT
TTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAGTATGTGTCAGTGGCACCCGTCCCAGACACCATG
GGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTGGTGATTGAAGACTTTGAGGAAGATTCAGAGGCT
GAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTGGCCAGGAAGATAGCTGAGCAGCAGCGTCGCCAG
GAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAAATCAGACCTTTGTTCCTCGTACCAGACACCAAC
GGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATCCTGGTGGTGCCCCTCATCGTGATCAATGAGCTG
GACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTGGTACAAGAGAAGGCCCGCAAGTCCATCGAGTTC
CTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGCAATGAACTCGAATCCATCGCCTTCCGCAGTGAG
GACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCACTACTGCAAAGACAAGGCTAAGGACTTCATGCCC
GCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGACCGGAACCTGCGTGTGAAGGCGCTCACAAGGAAT
GTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGGGCTGAGGGAGCCACACTGGGGCCCCCCCCCCGTGGAACCGTTCC
TGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTGCC

>561_561_15_ABR-SMG6_ABR_chr17_953289_ENST00000574437_SMG6_chr17_1989195_ENST00000536871_length(amino acids)=965AA_BP=665
MTCSSSGSNSRAAPPRLPAAPERAGPGACWLSPAPHQAQAPAQPPPGPGVDGAAGAMAAGGRRRRPLRYQSLAALVEDSQWPFLFLVSDF
SYGTDEYDGEGNEEQKGPPEGSETMPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIYINQLEA
LLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCS
QSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAV
TTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKM
KISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVEL
QVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGS
QSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTR
LEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLASLAR
LLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDD
LILSCCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG

--------------------------------------------------------------
>561_561_16_ABR-SMG6_ABR_chr17_953289_ENST00000574437_SMG6_chr17_1989195_ENST00000544865_length(transcript)=4674nt_BP=2118nt
ATAAAAAGCAAAATGGTGACTCAGAGAGGAGAGTTGGAAGCGTCCTGCCTCTTGCTCCCACTGTTAATTTTTACACTTGGAATTAGGCAG
AAGGCAAAGAAAACAGCAGCTTGAAATACGCGGCTGACATGCTCTTCATCGGGTAGCAACAGCAGAGCCGCTCCTCCCCGCCTCCCAGCA
GCCCCGGAGCGGGCAGGGCCCGGTGCCTGCTGGCTCTCCCCCGCCCCTCACCAGGCCCAGGCCCCCGCACAGCCCCCGCCCGGGCCAGGC
GTGGATGGTGCGGCCGGGGCCATGGCTGCCGGGGGCCGCCGCCGGCGCCCACTACGCTACCAGTCCCTGGCAGCTCTGGTGGAGGATTCT
CAGTGGCCTTTCTTGTTCCTTGTCTCAGACTTCAGCTACGGGACGGACGAGTACGACGGAGAGGGGAATGAGGAGCAGAAGGGGCCCCCG
GAGGGCTCAGAGACCATGCCGTACATCGATGAGTCGCCCACCATGTCCCCGCAGCTCAGCGCCCGCAGCCAGGGCGGGGGGGATGGCGTC
TCCCCGACTCCACCTGAGGGACTGGCTCCTGGGGTGGAAGCAGGGAAAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCC
AGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCATGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTC
ACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCTATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTG
CAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGCTGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTAT
AAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACCAGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAG
GACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGCTCTGCTCTACAAGCCCATTGACCGGGTCACTCGGAGCACCCTAGTCCTACAC
GACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGCTGCAGGATGCCCTCCGCATCTCCCAGAACTTCCTGTCCAGCATC
AACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGGGGGAGACGCGACAGCTGGTGAAGGACGGCTTCCTGGTGGAAGTG
TCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATGTCCTACTGTGTGCCAAGCTGAAGAAGACCTCTGCAGGGAAGCAC
CAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGTTTCCATCCCCCGAGGAGTCTGAGGCCAGCCCCCAGGTGCACCCC
TTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCCTCAAGAGTGAAATCCAGAAGGAGAAAGCCAACAAAGGCCAGAGC
CGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCCTGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAAT
CGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGAGGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGAT
CTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAGGATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACC
AGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTCATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAAC
CTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCAAAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGG
GATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAG
GACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCCAGGTTATTGCAGCTGACTGCAAAAGGGTCACAGTGCTGAAGTAT
TTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAGTATGTGTCAGTGGCACCCGTCCCAGACACCATG
GGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTGGTGATTGAAGACTTTGAGGAAGATTCAGAGGCT
GAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTGGCCAGGAAGATAGCTGAGCAGCAGCGTCGCCAG
GAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAAATCAGACCTTTGTTCCTCGTACCAGACACCAAC
GGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATCCTGGTGGTGCCCCTCATCGTGATCAATGAGCTG
GACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTGGTACAAGAGAAGGCCCGCAAGTCCATCGAGTTC
CTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGCAATGAACTCGAATCCATCGCCTTCCGCAGTGAG
GACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCACTACTGCAAAGACAAGGCTAAGGACTTCATGCCC
GCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGACCGGAACCTGCGTGTGAAGGCGCTCACAAGGAAT
GTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGGGCTGAGGGAGCCACACTGGGGCCCCCCCCCCGTGGAACCGTTCC
TGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTGCCTGAGCCACCAATCCACCCAGACAATAAACCATCCTCTTCCAA
CCCACGCCACGGCCATGCTGTGGGGGACCTGCTCCTCACAGAGCCCCTCCCAAGGATCGGGCGGAAGCTGCTGGGACCCTCCTGGGCTGC
CAGGATTTAGCAGGGAGGTGGCTGGCTACAGCAACAGCAGCTGGGCAAGCCAGATAGGCCGCCCATGCTCTCAGCCTTTCTCCCTCCCCC
GTCTCATTCCAAGGCTGAGGGAGGGCCTTCTCGCCTGGGGACGCAGCCACTTTCTCCAGTGGAGACAGGGCAGGGGTTCTGAGTTTCCGT
CAGATGCAGTGAAATCACAGTTCCCTTTCATCTTCAGAACCTCTGTCGTGAATGTGTTCAAGAGGCTTTGGTTAAGTCAGGAAGAAGTGC
CCAGGGTGTGTGTCCCCAGTCTCCCTGAGGCCTGGACTCGCCCATGAACCCAAGTCGGCTTCTAGACAGCATGTCCCTAACAGCAGCCCT
GGGCCCCCACCTCTTCTACCATCCACCCCAGACTTACCACACACCCTTCCTGCTGCTCCTCTTCCTGCCCTTATCAACCTGGGTCCCTCA
CACTTCGCCAGTTGCGTCCCCGTGGACAGTCATGAGTCTAGAGGAAAGGGGCATCTGGTCTCAGGCCCGTGCTCTCGGGTGGCCTCCACC
TGCTCCCTCTCTCCTCACTGGCCTTTCTTTCCGTCTAGCTTCCTCTTCAGGAAATGTCCTGACTCCCCTCAGCTCCCCCTTCACCCCTCC
TTGCCCGCCTACCCTCCCTCCAGAATAGCCCCTCACCCTTCTTCCCCTTCTAGTTGATCCTTTTCACCTCCCTGATCCCCTTCATTTCTT
CACCGCGGTTCCTCGTCATAGGGGTTCTCACTCTGAACTTTCCCTCTCTACTACCCATGGCAGGAACCTAGTACAGGTCTCCCACCCAGG
GCCTTCCACCCTCGGCTCCTGTGCTGGGAGAAACTTCCAGGCGTGGACAGCCCAGCCTGAGGCATTCCAGTGCTGGGGCACCGTCGCCTA
ACCTGGTTTCTAGCTTTGCCCTCACTCCCCGGAAAAACTGACACTGACACAGGGGCCCTTTCCTTGCCCCTTTAGCTGGTACCTCAGTGG
GGAGGCTTCCTTACCAAGAATGAGTTCCTGAAACCCAGGGCCAGAGACAAGGACAACTTAGGGGAAGACGGGGTTTTCGGTGGAGCCAGG
GGCAAATCTTAATGGGACCAGTGGGGGATACCCCAGAGCCCATGGCCTGACTGCACAGCCTGCCTGGAGGATGGGTGCGCAGCTCTGCCC
TCCCTGAGGCCCAGGACTATGCCAGAAGCGATGGGGTACCGTGTAGGGGAGCCAAGGCCAGTAGTTTGGGGGTAGGAGTCCCCTAGAGTC
TCAGAAGACTGGGCTCTTTGGAGTACAGGGTCCCCGGCCTCTCCTTTAAGATTCTCTCCCCAGCTGGAAGGCCGATGACTGGGTGGTCGG
GAGGGAGACCCAGCTCTCCTTTCTGTCCCGTTTGCAGCACTGGTTTTGTTTCCTTAATAAATTTTTAGTTATGAAACATACCTG

>561_561_16_ABR-SMG6_ABR_chr17_953289_ENST00000574437_SMG6_chr17_1989195_ENST00000544865_length(amino acids)=965AA_BP=665
MTCSSSGSNSRAAPPRLPAAPERAGPGACWLSPAPHQAQAPAQPPPGPGVDGAAGAMAAGGRRRRPLRYQSLAALVEDSQWPFLFLVSDF
SYGTDEYDGEGNEEQKGPPEGSETMPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIYINQLEA
LLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCS
QSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAV
TTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKM
KISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVEL
QVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGS
QSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTR
LEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLASLAR
LLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDD
LILSCCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ABR-SMG6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneSMG6chr17:953289chr17:1989195ENST000002630731219114_5031119.01420.0telomeric DNA
TgeneSMG6chr17:953289chr17:1989195ENST00000354901512114_503211.0512.0telomeric DNA
TgeneSMG6chr17:953289chr17:1989195ENST00000536871411114_503211.0512.0telomeric DNA
TgeneSMG6chr17:953289chr17:1989195ENST000005448651219114_5031088.01389.0telomeric DNA


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ABR-SMG6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ABR-SMG6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneABRC0033578Prostatic Neoplasms1CTD_human
HgeneABRC0376358Malignant neoplasm of prostate1CTD_human