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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ANXA11-ZMIZ1 (FusionGDB2 ID:HG311TG57178)

Fusion Gene Summary for ANXA11-ZMIZ1

check button Fusion gene summary
Fusion gene informationFusion gene name: ANXA11-ZMIZ1
Fusion gene ID: hg311tg57178
HgeneTgene
Gene symbol

ANXA11

ZMIZ1

Gene ID

311

57178

Gene nameannexin A11zinc finger MIZ-type containing 1
SynonymsALS23|ANX11|CAP-50|CAP50MIZ|NEDDFSA|RAI17|TRAFIP10|ZIMP10
Cytomap('ANXA11')('ZMIZ1')

10q22.3

10q22.3

Type of geneprotein-codingprotein-coding
Descriptionannexin A1156 kDa autoantigenannexin XIannexin-11calcyclin-associated annexin 50epididymis secretory sperm binding proteinzinc finger MIZ domain-containing protein 1retinoic acid induced 17zinc finger-containing, Miz1, PIAS-like protein on chromosome 10
Modification date2020031320200315
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000265447, ENST00000360615, 
ENST00000372231, ENST00000422982, 
ENST00000438331, ENST00000535999, 
ENST00000537102, ENST00000463657, 
Fusion gene scores* DoF score11 X 8 X 4=3527 X 8 X 5=280
# samples 118
** MAII scorelog2(11/352*10)=-1.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(8/280*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANXA11 [Title/Abstract] AND ZMIZ1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANXA11(81917396)-ZMIZ1(81036937), # samples:1
Anticipated loss of major functional domain due to fusion event.ANXA11-ZMIZ1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ANXA11-ZMIZ1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ANXA11-ZMIZ1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ANXA11-ZMIZ1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ANXA11-ZMIZ1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneANXA11

GO:0051592

response to calcium ion

9188810|12601007

TgeneZMIZ1

GO:0007179

transforming growth factor beta receptor signaling pathway

16777850

TgeneZMIZ1

GO:0030521

androgen receptor signaling pathway

14609956

TgeneZMIZ1

GO:0033233

regulation of protein sumoylation

14609956

TgeneZMIZ1

GO:0045944

positive regulation of transcription by RNA polymerase II

26522984

TgeneZMIZ1

GO:0060395

SMAD protein signal transduction

16777850

TgeneZMIZ1

GO:1903508

positive regulation of nucleic acid-templated transcription

14609956|16777850


check buttonFusion gene breakpoints across ANXA11 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ZMIZ1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4KIRCTCGA-BP-4770ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+


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Fusion Gene ORF analysis for ANXA11-ZMIZ1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000265447ENST00000446377ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
5CDS-intronENST00000360615ENST00000446377ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
5CDS-intronENST00000372231ENST00000446377ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
5CDS-intronENST00000422982ENST00000446377ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
5CDS-intronENST00000438331ENST00000446377ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
5CDS-intronENST00000535999ENST00000446377ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
5CDS-intronENST00000537102ENST00000446377ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
Frame-shiftENST00000265447ENST00000334512ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
Frame-shiftENST00000360615ENST00000334512ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
Frame-shiftENST00000372231ENST00000334512ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
Frame-shiftENST00000372231ENST00000478357ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
Frame-shiftENST00000422982ENST00000334512ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
Frame-shiftENST00000438331ENST00000478357ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
Frame-shiftENST00000535999ENST00000334512ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
Frame-shiftENST00000535999ENST00000478357ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
Frame-shiftENST00000537102ENST00000478357ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
In-frameENST00000265447ENST00000478357ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
In-frameENST00000360615ENST00000478357ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
In-frameENST00000422982ENST00000478357ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
In-frameENST00000438331ENST00000334512ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
In-frameENST00000537102ENST00000334512ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
intron-3CDSENST00000463657ENST00000334512ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
intron-3CDSENST00000463657ENST00000478357ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+
intron-intronENST00000463657ENST00000446377ANXA11chr10

81917396

-ZMIZ1chr10

81036937

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000438331ANXA11chr1081917396-ENST00000334512ZMIZ1chr1081036937+8635194119434864973
ENST00000360615ANXA11chr1081917396-ENST00000478357ZMIZ1chr1081036937+619219404462089547
ENST00000265447ANXA11chr1081917396-ENST00000478357ZMIZ1chr1081036937+59971745531894613
ENST00000422982ANXA11chr1081917396-ENST00000478357ZMIZ1chr1081036937+599717452871894535
ENST00000537102ANXA11chr1081917396-ENST00000334512ZMIZ1chr1081036937+8694200020024923973

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000438331ENST00000334512ANXA11chr1081917396-ZMIZ1chr1081036937+0.0086001740.9913999
ENST00000360615ENST00000478357ANXA11chr1081917396-ZMIZ1chr1081036937+0.0121101640.9878898
ENST00000265447ENST00000478357ANXA11chr1081917396-ZMIZ1chr1081036937+0.0125100430.98749
ENST00000422982ENST00000478357ANXA11chr1081917396-ZMIZ1chr1081036937+0.0117847540.9882152
ENST00000537102ENST00000334512ANXA11chr1081917396-ZMIZ1chr1081036937+0.0098986060.99010134

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Fusion Genomic Features for ANXA11-ZMIZ1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ANXA11chr1081917396-ZMIZ1chr1081036935+0.0011154020.9988846
ANXA11chr1081917396-ZMIZ1chr1081036935+0.0011154020.9988846

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ANXA11-ZMIZ1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:81917396/chr10:81036937)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANXA11chr10:81917396chr10:81036937ENST00000265447-1415200_271486506.0RepeatAnnexin 1
HgeneANXA11chr10:81917396chr10:81036937ENST00000265447-1415272_343486506.0RepeatAnnexin 2
HgeneANXA11chr10:81917396chr10:81036937ENST00000265447-1415355_427486506.0RepeatAnnexin 3
HgeneANXA11chr10:81917396chr10:81036937ENST00000360615-1516200_271486506.0RepeatAnnexin 1
HgeneANXA11chr10:81917396chr10:81036937ENST00000360615-1516272_343486506.0RepeatAnnexin 2
HgeneANXA11chr10:81917396chr10:81036937ENST00000360615-1516355_427486506.0RepeatAnnexin 3
HgeneANXA11chr10:81917396chr10:81036937ENST00000372231-1415200_271486506.0RepeatAnnexin 1
HgeneANXA11chr10:81917396chr10:81036937ENST00000372231-1415272_343486506.0RepeatAnnexin 2
HgeneANXA11chr10:81917396chr10:81036937ENST00000372231-1415355_427486506.0RepeatAnnexin 3
HgeneANXA11chr10:81917396chr10:81036937ENST00000422982-1516200_271486506.0RepeatAnnexin 1
HgeneANXA11chr10:81917396chr10:81036937ENST00000422982-1516272_343486506.0RepeatAnnexin 2
HgeneANXA11chr10:81917396chr10:81036937ENST00000422982-1516355_427486506.0RepeatAnnexin 3
HgeneANXA11chr10:81917396chr10:81036937ENST00000438331-1617200_271486506.0RepeatAnnexin 1
HgeneANXA11chr10:81917396chr10:81036937ENST00000438331-1617272_343486506.0RepeatAnnexin 2
HgeneANXA11chr10:81917396chr10:81036937ENST00000438331-1617355_427486506.0RepeatAnnexin 3
HgeneANXA11chr10:81917396chr10:81036937ENST00000535999-1617200_271486506.0RepeatAnnexin 1
HgeneANXA11chr10:81917396chr10:81036937ENST00000535999-1617272_343486506.0RepeatAnnexin 2
HgeneANXA11chr10:81917396chr10:81036937ENST00000535999-1617355_427486506.0RepeatAnnexin 3
TgeneZMIZ1chr10:81917396chr10:81036937ENST00000334512625280_305931068.0Compositional biasNote=Ala-rich
TgeneZMIZ1chr10:81917396chr10:81036937ENST00000334512625334_555931068.0Compositional biasNote=Pro-rich
TgeneZMIZ1chr10:81917396chr10:81036937ENST00000334512625867_1002931068.0Compositional biasNote=Pro-rich
TgeneZMIZ1chr10:81917396chr10:81036937ENST00000334512625837_1067931068.0RegionTransactivation domain
TgeneZMIZ1chr10:81917396chr10:81036937ENST00000334512625727_804931068.0Zinc fingerSP-RING-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANXA11chr10:81917396chr10:81036937ENST00000265447-1415431_502486506.0RepeatAnnexin 4
HgeneANXA11chr10:81917396chr10:81036937ENST00000360615-1516431_502486506.0RepeatAnnexin 4
HgeneANXA11chr10:81917396chr10:81036937ENST00000372231-1415431_502486506.0RepeatAnnexin 4
HgeneANXA11chr10:81917396chr10:81036937ENST00000422982-1516431_502486506.0RepeatAnnexin 4
HgeneANXA11chr10:81917396chr10:81036937ENST00000438331-1617431_502486506.0RepeatAnnexin 4
HgeneANXA11chr10:81917396chr10:81036937ENST00000535999-1617431_502486506.0RepeatAnnexin 4


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Fusion Gene Sequence for ANXA11-ZMIZ1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>5016_5016_1_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000265447_ZMIZ1_chr10_81036937_ENST00000478357_length(transcript)=5997nt_BP=1745nt
GCACTGCCTCTGGCACCTGGGGCAGCCGCGCCCGCGGAGTTTTCCGCCCGGCGCTGACGGCTGCTGCGCCCGCGGCTCCCCAGTGCCCCG
AGTGCCCCGCGGGCCCCGCGAGCGGGAGTGGGACCCAGCCCCTAGGCAGAACCCAGGCGCCGCGCCCGGGACGCCCGCGGAGAGAGCCAC
TCCCGCCCACGTCCCATTTCGCCCCTCGCGTCCGGAGTCCCCGTGGCCAGGTGAGGGCTCTCAGGCAGAGCCTGAATGTGCTTTCGTCTT
CTCTTCCAGATCTAACCATGAGCTACCCTGGCTATCCCCCGCCCCCAGGTGGCTACCCACCAGCTGCACCAGGTGGTGGTCCCTGGGGAG
GTGCTGCCTACCCTCCTCCGCCCAGCATGCCCCCCATCGGGCTGGATAACGTGGCCACCTATGCGGGGCAGTTCAACCAGGACTATCTCT
CGGGAATGGCGGCCAACATGTCTGGGACATTTGGAGGAGCCAACATGCCCAACCTGTACCCTGGGGCCCCTGGGGCTGGCTACCCACCAG
TGCCCCCTGGCGGCTTTGGGCAGCCCCCCTCTGCCCAGCAGCCTGTTCCTCCCTATGGGATGTATCCACCCCCAGGAGGAAACCCACCCT
CCAGGATGCCCTCATATCCGCCATACCCAGGGGCCCCTGTGCCGGGCCAGCCCATGCCACCCCCCGGACAGCAGCCCCCAGGGGCCTACC
CTGGGCAGCCACCAGTGACCTACCCTGGTCAGCCTCCAGTGCCACTCCCTGGGCAGCAGCAGCCAGTGCCGAGCTACCCAGGATACCCGG
GGTCTGGGACTGTCACCCCCGCTGTGCCCCCAACCCAGTTTGGAAGCCGAGGCACCATCACTGATGCTCCCGGCTTTGACCCCCTGCGAG
ATGCCGAGGTCCTGCGGAAGGCCATGAAAGGCTTCGGGACGGATGAGCAGGCCATCATTGACTGCCTGGGGAGTCGCTCCAACAAGCAGC
GGCAGCAGATCCTACTTTCCTTCAAGACGGCTTACGGCAAGGATTTGATCAAAGATCTGAAATCTGAACTGTCAGGAAACTTTGAGAAGA
CAATCTTGGCTCTGATGAAGACCCCAGTCCTCTTTGACATTTATGAGATAAAGGAAGCCATCAAGGGGGTTGGCACTGATGAAGCCTGCC
TGATTGAGATCCTCGCTTCCCGCAGCAATGAGCACATCCGAGAATTAAACAGAGCCTACAAAGCAGAATTCAAAAAGACCCTGGAAGAGG
CCATTCGAAGCGACACATCAGGGCACTTCCAGCGGCTCCTCATCTCTCTCTCTCAGGGAAACCGTGATGAAAGCACAAACGTGGACATGT
CACTCGCCCAGAGAGATGCCCAGGAGCTGTATGCGGCCGGGGAGAACCGCCTGGGAACAGACGAGTCCAAGTTCAATGCGGTTCTGTGCT
CCCGGAGCCGGGCCCACCTGGTAGCAGTTTTCAATGAGTACCAGAGAATGACAGGCCGGGACATTGAGAAGAGCATCTGCCGGGAGATGT
CCGGGGACCTGGAGGAGGGCATGCTGGCCGTGGTGAAATGTCTCAAGAATACCCCAGCCTTCTTTGCGGAGAGGCTCAACAAGGCCATGA
GGGGGGCAGGAACAAAGGACCGGACCCTGATTCGCATCATGGTGTCTCGCAGCGAGACCGACCTCCTGGACATCAGATCAGAGTATAAGC
GGATGTACGGCAAGTCGCTGTACCACGACATCTCGAGCCTTGTTGTCCTCCTGGTGCGAAGAGCTCGGCCGCCTGCTGCTGCTCCGACAT
CAGAAGAGCCGCCAGAGCGATCCCCCTGGGAAACTCCCCATGCAGCCCCCTCTCAGCTCCATGAGCTCCATGAAACCCACTCTGTCGCAC
AGTGATGGGTCGTTCCCCTATGACTCTGTCCCTTGGCAGCAGAACACCAACCAGCCTCCCGGCTCCCTTTCCGTGGTCACCACGGTTTGG
GGAGTAACCAACACATCCCAGAGCCAGGTCCTTGGGAACCCTATGGCCAATGCCAACAACCCCATGAATCCAGGCGGCAACCCCATGGCG
TCGGGCATGACCACCAGCAACCCAGGCCTCAACTCCCCACAGTTTGCGGGGCAGCAGCAGCAGTTCTCAGCCAAGGCTGGCCCCGCTCAG
CCCTACATCCAGCAGAGCATGTATGGCCGGCCCAACTACCCCGGCAGCGGGGGCTTTGGGGCCAGTTACCCTGGGGGTCCTAACGCCCCC
GCAGGCATGGGCATCCCTCCGCACACCAGGCCGCCTGCTGACTTCACTCAGCCCGCGGCAGCCGCTGCAGCAGCGGCAGTGGCAGCAGCA
GCAGCCACAGCTACAGCCACAGCCACGGCCACTGTGGCAGCCCTGCAGGAGACACAGAACAAGGATATAAACCAGTATGGACCGGTCTGT
TCCTCTTTCCAGATGGGTCCCACCCAGGCGTATAACAGCCAATTCATGAACCAGCCCGGGCCGCGGGGGCCTGCCTCCATGGGGGGCAGC
ATGAACCCCGCGAGCATGGCGGCTGGCATGACGCCCTCGGGGATGAGCGGCCCTCCCATGGGCATGAACCAGCCCCGGCCGCCCGGCATC
AGCCCCTTTGGCACACACGGGCAGCGGATGCCCCAGCAGACCTACCCGGGCCCCCGGCCCCAGTCCCTTCCTATTCAGAACATAAAGAGG
CCATACCCTGGAGAGGTGAGTGCAGCAGTGGGAGCCTGGGAGGTGGGAACTGGGACACCTGGGCTTGAAGACATGGGCCGTGGGTACGGC
TTTGGAAGGGGTGTGGCTTGGACTCCAGCACACTTGGACAAAGAGGCAGGGGCTTAGGGGTCAGGTGCTCCTGGGTTTGAGACCTGGTTC
TGCTGTTTCCCAACTGAAAGACCTCGAGCCAGTCACCCTGCCTCCTAGGGCTGCTTGAGGGACTTGAGGAGGTGTCCGTGAAGTGCTTGG
CCCTGGGCTGGCATGTGCCGCCACTCAGCAAGCAGCAGTTCCTCTTACTGTAGTGACTCTTGTCTTGGCTCAGCCACTAACTGGGTGACC
TGGGTTTAGTTCCTCCTGCCCACATGAGAGCTTCCCCAACTCCTCTCCAAGAAAGAGAGCTGAGACAAAATGCTTCCAGTCTATAAGGGC
TGACCCGTCCGGGAAGTGACTGGAAGGCAGGCAGCGTGTTTCCAGTCTGTAAGGATTGACCTGTTGGGGAAGTGACTGGAAGGCAGAGAG
CGTGTTTCCAATCTATAAGGACTGACCCGTTGGGGAAGTGACTGGAAGGCCGGCAGCTGTTTCCAGTCTATAAGGACTGACCCGTCAGGG
AAGTGACTGGAAGGCAGACAGCGTGTTTCTTAGCTCTTGTTTCCATCCACACTTGGTCACTGTATAGGAAGTGGCACTGCCTCTTGGGCT
GCACAGCCAGCTCAGCCAAGGTGTTGGGGAAGATTTGGGGAAGTAAAACCCACACCTCCTGCCCTCTGGGAAGTGAGGTTTTAGCAGGAA
AGAAAAGTTTTTAGCAGAGACTCACCAGGGAATGAAGCATAGCAGACTGCACAGAACTCAATATGAGTCAGAGAAGGCAGGCTTCCTGGA
GGGTGTGTCACAAGTAAATCCTCAGAAAATGATGCTGGCAGCAGCTGGCCCATCTGGGTACCCAGGTAAGGATTTAGTTTACCTGCAGAA
GACGTAGGGACGTGGCTCTGCAGATGCCCCTCGTGAAGCCCTGGTTGCTCCCCACGACCAAGCCCCTTTTTGAGCAGGGTGTGCCCAGCT
CTCTGCCTGCCTCCCTCCCAGCTTGCATGCCCACTCTCAGAGCAGTTTTCTCCTCCTAGCTCCTCTCAGCTCTGTGGCCTTCACCTTGGG
TTCACAGCGGCTTTAGATTCCAAAGACCTTAAGTTCCTTGAAGATCTGCACATTTCCCCTCAGTATCCACCTTAGGATGGGCGGGGAGGC
TTGGCAACAAGTGGAGGTATTCTGAGTTCAGGAGGGGAGAGAGAGGGGGGGGGGTCAGGGGCTTCCTCATGCATCCAAGAAGCTGGATCA
AGCCCCAACCCTCCACCTGGTGGACACTAGTTCAGGGAGGGGCCAGAGAAGGACCATTGGCTCCTGGGTCCTGAGTTTGGGGGAGCCTCA
AGCTATTGGCACCTCTCCTGGCACTCAGGCCCCATGCAGTTTCTAGGCCTTTTCTCAGCCACCCTGTGCTCAAAATCCCAGTGTCCCACT
GGCTGTGCTGGGGGTGCATCTGTTAGCCCACGCCAAAGGAGGCAATCTCGGATGAGGCTTCAGCAGAATTCCTGGTCATTGGTGTCACCC
CTGCACCTGCACCTGTGCCATGCTTATGGCTCTTGCCTGCCTAAAGAGAGCACACCAAAGGCTCTCCATATTTTTACTAAATTAATCATC
CTTTTCATAGAGTGCTGCTGCTACCCAGCTACAGCACTGGGTGGTCACAGCCTATGCGGCCTGATCCTGTCTGGAAGACTGGCCTTCCTT
CCCCTTGCCATGGCTTGTTCATACAATATTTGAATTGTTGGAGCCTTAGGACAGGGGTTGGGTCATCTGGTCCCACAGAGGACTCTCTTC
TCTAGCTTGGTGGGCAGGTAGGCACCAGCTACGTCTTCTATACCTCCTGTGGTGGGTGCCTCACTGTCACCCAGAGCAGCCACCATGTTG
CAACAACGTGAGTTGTAGATTCTTCCACACTGACACTTTCTGACATTTATCCCTAAGTCCATCATTCGTTTGTTGAGCAAGTATTAAGGG
TATTTTCCCAGGCACTGGGGCACAGCCACCAACAGGACCTCTGGGCAAGAGAGACACTCAGATGGGGAAGAAGAAACCACTGACTCACAG
GATGTCATGTGGCCGTGAGGGTCACCTGATTTTCCAGACAGGGAAGGTGGCTGGAGGGTGGTGCTCTCTCCTCTTCTCTAAATTGTCTGT
CCCGGGAGAAGTTGTCTTGTTCCTTCACCAACCTGGCTCTCCCACCTCCTGCACAGGTGGCAGGTTGTCGATGGCCCAGAACTGAACACT
AGGTGTGTGTTCTGCTCTGAGGGGAGTACGAGGACAATGCCACCCAAGTTCAGCCTTGGAATGCAGGGGCACAGGGGGCTCCTTTCTGGA
ATTGCATCCTGTTGACTGTGTTCCTCTGTCACATTGGGGTACACATTGGGGAGCACAGCCCTAACCCAGGCACCAGGAGAGACACAAAGG
TCGGGGGAGTTAGAATCAGGCCCCTCATAATGGTGTGAGCAAGAGGCTCTGAAAGTGTCCCTGGAGTTCAGGGGCACATGTGCTCCAGGA
AGAACGGCCTCAAGGGGAGGTGGCCTATGATCTGGACAGGCAGAACAAAATGCCCCTGGATGTCAGGACGAGAAGGGGCCCAAAGCATTA
TCTGGTTTTGTGGGTGGGAAACAGCAGGAGCAAATGAGGAGAGGCGGGCCCCATCCCGTTGTTCAGGTGACCTGGCTATGTGACGTTGGC
AACATTGAACGTGTTTCCCCTCTCCTTTCTCTCCCACCACAGCCCAACTATGGAAACCAGCAATATGGACCAAACAGCCAGTTCCCCACC
CAGCCAGGCCAGTACCCAGCCCCCAACCCCCCGAGGCCACTCACCTCCCCCAACTACCCAGGACAGAGGATGCCCAGCCAGCCGAGCTCC
GGGCAGTACCCGCCCCCCACGGTCAACATGGGGCAGTATTACAAGGTGAGTCCCAGCCTCGCCACCACCCACGGGGCCCCTTCCCTCCTA
ACCACCTCACTCCCCTAACTCCACCGGGATCACTCTGACCCTGCGTGTGTTTGCCCCAAGGACAGCGAGGGGTGGGTGATTTCTGAACGT
CCCCATGTGTTCAGGGCGAAGTTCGGTGGCCAGAATGTCAGAGTGGCTTTTCTCAGTTCCTATTCTCATTCGTCTCGGATGATGGTTTTT

>5016_5016_1_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000265447_ZMIZ1_chr10_81036937_ENST00000478357_length(amino acids)=613AA_BP=564
MTAAAPAAPQCPECPAGPASGSGTQPLGRTQAPRPGRPRREPLPPTSHFAPRVRSPRGQVRALRQSLNVLSSSLPDLTMSYPGYPPPPGG
YPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPP
YGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVTPAVPPTQFGSRG
TITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIK
EAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRL
GTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRS

--------------------------------------------------------------
>5016_5016_2_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000360615_ZMIZ1_chr10_81036937_ENST00000478357_length(transcript)=6192nt_BP=1940nt
GCACTGCCTCTGGCACCTGGGGCAGCCGCGCCCGCGGAGTTTTCCGCCCGGCGCTGACGGCTGCTGCGCCCGCGGCTCCCCAGTGCCCCG
AGTGCCCCGCGGGCCCCGCGAGCGGGAGTGGGACCCAGCCCCTAGGCAGAACCCAGGCGCCGCGCCCGGGACGCCCGCGGAGAGAGCCAC
TCCCGCCCACGTCCCATTTCGCCCCTCGCGTCCGGAGTCCCCGTGGCCAGGGATTATTGGACCTGCCTGGTTTAAACTATTGTCTTAGTT
AATTTTGTGCTGCTCTAACAAAATATCACAGACTGAGTAATTTATAAGCAATAGTAGCTTATTTGGCTCACAGTTCTGGAGGCTGAGAAG
ATCGTGAGGCTGCATCTGGCAAGGGCCTTCTTGCTGCTTCATAACATGGCAGAAGACATCATGCGGCAGGGGCTCTCAGGCAGAGCCTGA
ATGTGCTTTCGTCTTCTCTTCCAGATCTAACCATGAGCTACCCTGGCTATCCCCCGCCCCCAGGTGGCTACCCACCAGCTGCACCAGGTG
GTGGTCCCTGGGGAGGTGCTGCCTACCCTCCTCCGCCCAGCATGCCCCCCATCGGGCTGGATAACGTGGCCACCTATGCGGGGCAGTTCA
ACCAGGACTATCTCTCGGGAATGGCGGCCAACATGTCTGGGACATTTGGAGGAGCCAACATGCCCAACCTGTACCCTGGGGCCCCTGGGG
CTGGCTACCCACCAGTGCCCCCTGGCGGCTTTGGGCAGCCCCCCTCTGCCCAGCAGCCTGTTCCTCCCTATGGGATGTATCCACCCCCAG
GAGGAAACCCACCCTCCAGGATGCCCTCATATCCGCCATACCCAGGGGCCCCTGTGCCGGGCCAGCCCATGCCACCCCCCGGACAGCAGC
CCCCAGGGGCCTACCCTGGGCAGCCACCAGTGACCTACCCTGGTCAGCCTCCAGTGCCACTCCCTGGGCAGCAGCAGCCAGTGCCGAGCT
ACCCAGGATACCCGGGGTCTGGGACTGTCACCCCCGCTGTGCCCCCAACCCAGTTTGGAAGCCGAGGCACCATCACTGATGCTCCCGGCT
TTGACCCCCTGCGAGATGCCGAGGTCCTGCGGAAGGCCATGAAAGGCTTCGGGACGGATGAGCAGGCCATCATTGACTGCCTGGGGAGTC
GCTCCAACAAGCAGCGGCAGCAGATCCTACTTTCCTTCAAGACGGCTTACGGCAAGGATTTGATCAAAGATCTGAAATCTGAACTGTCAG
GAAACTTTGAGAAGACAATCTTGGCTCTGATGAAGACCCCAGTCCTCTTTGACATTTATGAGATAAAGGAAGCCATCAAGGGGGTTGGCA
CTGATGAAGCCTGCCTGATTGAGATCCTCGCTTCCCGCAGCAATGAGCACATCCGAGAATTAAACAGAGCCTACAAAGCAGAATTCAAAA
AGACCCTGGAAGAGGCCATTCGAAGCGACACATCAGGGCACTTCCAGCGGCTCCTCATCTCTCTCTCTCAGGGAAACCGTGATGAAAGCA
CAAACGTGGACATGTCACTCGCCCAGAGAGATGCCCAGGAGCTGTATGCGGCCGGGGAGAACCGCCTGGGAACAGACGAGTCCAAGTTCA
ATGCGGTTCTGTGCTCCCGGAGCCGGGCCCACCTGGTAGCAGTTTTCAATGAGTACCAGAGAATGACAGGCCGGGACATTGAGAAGAGCA
TCTGCCGGGAGATGTCCGGGGACCTGGAGGAGGGCATGCTGGCCGTGGTGAAATGTCTCAAGAATACCCCAGCCTTCTTTGCGGAGAGGC
TCAACAAGGCCATGAGGGGGGCAGGAACAAAGGACCGGACCCTGATTCGCATCATGGTGTCTCGCAGCGAGACCGACCTCCTGGACATCA
GATCAGAGTATAAGCGGATGTACGGCAAGTCGCTGTACCACGACATCTCGAGCCTTGTTGTCCTCCTGGTGCGAAGAGCTCGGCCGCCTG
CTGCTGCTCCGACATCAGAAGAGCCGCCAGAGCGATCCCCCTGGGAAACTCCCCATGCAGCCCCCTCTCAGCTCCATGAGCTCCATGAAA
CCCACTCTGTCGCACAGTGATGGGTCGTTCCCCTATGACTCTGTCCCTTGGCAGCAGAACACCAACCAGCCTCCCGGCTCCCTTTCCGTG
GTCACCACGGTTTGGGGAGTAACCAACACATCCCAGAGCCAGGTCCTTGGGAACCCTATGGCCAATGCCAACAACCCCATGAATCCAGGC
GGCAACCCCATGGCGTCGGGCATGACCACCAGCAACCCAGGCCTCAACTCCCCACAGTTTGCGGGGCAGCAGCAGCAGTTCTCAGCCAAG
GCTGGCCCCGCTCAGCCCTACATCCAGCAGAGCATGTATGGCCGGCCCAACTACCCCGGCAGCGGGGGCTTTGGGGCCAGTTACCCTGGG
GGTCCTAACGCCCCCGCAGGCATGGGCATCCCTCCGCACACCAGGCCGCCTGCTGACTTCACTCAGCCCGCGGCAGCCGCTGCAGCAGCG
GCAGTGGCAGCAGCAGCAGCCACAGCTACAGCCACAGCCACGGCCACTGTGGCAGCCCTGCAGGAGACACAGAACAAGGATATAAACCAG
TATGGACCGGTCTGTTCCTCTTTCCAGATGGGTCCCACCCAGGCGTATAACAGCCAATTCATGAACCAGCCCGGGCCGCGGGGGCCTGCC
TCCATGGGGGGCAGCATGAACCCCGCGAGCATGGCGGCTGGCATGACGCCCTCGGGGATGAGCGGCCCTCCCATGGGCATGAACCAGCCC
CGGCCGCCCGGCATCAGCCCCTTTGGCACACACGGGCAGCGGATGCCCCAGCAGACCTACCCGGGCCCCCGGCCCCAGTCCCTTCCTATT
CAGAACATAAAGAGGCCATACCCTGGAGAGGTGAGTGCAGCAGTGGGAGCCTGGGAGGTGGGAACTGGGACACCTGGGCTTGAAGACATG
GGCCGTGGGTACGGCTTTGGAAGGGGTGTGGCTTGGACTCCAGCACACTTGGACAAAGAGGCAGGGGCTTAGGGGTCAGGTGCTCCTGGG
TTTGAGACCTGGTTCTGCTGTTTCCCAACTGAAAGACCTCGAGCCAGTCACCCTGCCTCCTAGGGCTGCTTGAGGGACTTGAGGAGGTGT
CCGTGAAGTGCTTGGCCCTGGGCTGGCATGTGCCGCCACTCAGCAAGCAGCAGTTCCTCTTACTGTAGTGACTCTTGTCTTGGCTCAGCC
ACTAACTGGGTGACCTGGGTTTAGTTCCTCCTGCCCACATGAGAGCTTCCCCAACTCCTCTCCAAGAAAGAGAGCTGAGACAAAATGCTT
CCAGTCTATAAGGGCTGACCCGTCCGGGAAGTGACTGGAAGGCAGGCAGCGTGTTTCCAGTCTGTAAGGATTGACCTGTTGGGGAAGTGA
CTGGAAGGCAGAGAGCGTGTTTCCAATCTATAAGGACTGACCCGTTGGGGAAGTGACTGGAAGGCCGGCAGCTGTTTCCAGTCTATAAGG
ACTGACCCGTCAGGGAAGTGACTGGAAGGCAGACAGCGTGTTTCTTAGCTCTTGTTTCCATCCACACTTGGTCACTGTATAGGAAGTGGC
ACTGCCTCTTGGGCTGCACAGCCAGCTCAGCCAAGGTGTTGGGGAAGATTTGGGGAAGTAAAACCCACACCTCCTGCCCTCTGGGAAGTG
AGGTTTTAGCAGGAAAGAAAAGTTTTTAGCAGAGACTCACCAGGGAATGAAGCATAGCAGACTGCACAGAACTCAATATGAGTCAGAGAA
GGCAGGCTTCCTGGAGGGTGTGTCACAAGTAAATCCTCAGAAAATGATGCTGGCAGCAGCTGGCCCATCTGGGTACCCAGGTAAGGATTT
AGTTTACCTGCAGAAGACGTAGGGACGTGGCTCTGCAGATGCCCCTCGTGAAGCCCTGGTTGCTCCCCACGACCAAGCCCCTTTTTGAGC
AGGGTGTGCCCAGCTCTCTGCCTGCCTCCCTCCCAGCTTGCATGCCCACTCTCAGAGCAGTTTTCTCCTCCTAGCTCCTCTCAGCTCTGT
GGCCTTCACCTTGGGTTCACAGCGGCTTTAGATTCCAAAGACCTTAAGTTCCTTGAAGATCTGCACATTTCCCCTCAGTATCCACCTTAG
GATGGGCGGGGAGGCTTGGCAACAAGTGGAGGTATTCTGAGTTCAGGAGGGGAGAGAGAGGGGGGGGGGTCAGGGGCTTCCTCATGCATC
CAAGAAGCTGGATCAAGCCCCAACCCTCCACCTGGTGGACACTAGTTCAGGGAGGGGCCAGAGAAGGACCATTGGCTCCTGGGTCCTGAG
TTTGGGGGAGCCTCAAGCTATTGGCACCTCTCCTGGCACTCAGGCCCCATGCAGTTTCTAGGCCTTTTCTCAGCCACCCTGTGCTCAAAA
TCCCAGTGTCCCACTGGCTGTGCTGGGGGTGCATCTGTTAGCCCACGCCAAAGGAGGCAATCTCGGATGAGGCTTCAGCAGAATTCCTGG
TCATTGGTGTCACCCCTGCACCTGCACCTGTGCCATGCTTATGGCTCTTGCCTGCCTAAAGAGAGCACACCAAAGGCTCTCCATATTTTT
ACTAAATTAATCATCCTTTTCATAGAGTGCTGCTGCTACCCAGCTACAGCACTGGGTGGTCACAGCCTATGCGGCCTGATCCTGTCTGGA
AGACTGGCCTTCCTTCCCCTTGCCATGGCTTGTTCATACAATATTTGAATTGTTGGAGCCTTAGGACAGGGGTTGGGTCATCTGGTCCCA
CAGAGGACTCTCTTCTCTAGCTTGGTGGGCAGGTAGGCACCAGCTACGTCTTCTATACCTCCTGTGGTGGGTGCCTCACTGTCACCCAGA
GCAGCCACCATGTTGCAACAACGTGAGTTGTAGATTCTTCCACACTGACACTTTCTGACATTTATCCCTAAGTCCATCATTCGTTTGTTG
AGCAAGTATTAAGGGTATTTTCCCAGGCACTGGGGCACAGCCACCAACAGGACCTCTGGGCAAGAGAGACACTCAGATGGGGAAGAAGAA
ACCACTGACTCACAGGATGTCATGTGGCCGTGAGGGTCACCTGATTTTCCAGACAGGGAAGGTGGCTGGAGGGTGGTGCTCTCTCCTCTT
CTCTAAATTGTCTGTCCCGGGAGAAGTTGTCTTGTTCCTTCACCAACCTGGCTCTCCCACCTCCTGCACAGGTGGCAGGTTGTCGATGGC
CCAGAACTGAACACTAGGTGTGTGTTCTGCTCTGAGGGGAGTACGAGGACAATGCCACCCAAGTTCAGCCTTGGAATGCAGGGGCACAGG
GGGCTCCTTTCTGGAATTGCATCCTGTTGACTGTGTTCCTCTGTCACATTGGGGTACACATTGGGGAGCACAGCCCTAACCCAGGCACCA
GGAGAGACACAAAGGTCGGGGGAGTTAGAATCAGGCCCCTCATAATGGTGTGAGCAAGAGGCTCTGAAAGTGTCCCTGGAGTTCAGGGGC
ACATGTGCTCCAGGAAGAACGGCCTCAAGGGGAGGTGGCCTATGATCTGGACAGGCAGAACAAAATGCCCCTGGATGTCAGGACGAGAAG
GGGCCCAAAGCATTATCTGGTTTTGTGGGTGGGAAACAGCAGGAGCAAATGAGGAGAGGCGGGCCCCATCCCGTTGTTCAGGTGACCTGG
CTATGTGACGTTGGCAACATTGAACGTGTTTCCCCTCTCCTTTCTCTCCCACCACAGCCCAACTATGGAAACCAGCAATATGGACCAAAC
AGCCAGTTCCCCACCCAGCCAGGCCAGTACCCAGCCCCCAACCCCCCGAGGCCACTCACCTCCCCCAACTACCCAGGACAGAGGATGCCC
AGCCAGCCGAGCTCCGGGCAGTACCCGCCCCCCACGGTCAACATGGGGCAGTATTACAAGGTGAGTCCCAGCCTCGCCACCACCCACGGG
GCCCCTTCCCTCCTAACCACCTCACTCCCCTAACTCCACCGGGATCACTCTGACCCTGCGTGTGTTTGCCCCAAGGACAGCGAGGGGTGG
GTGATTTCTGAACGTCCCCATGTGTTCAGGGCGAAGTTCGGTGGCCAGAATGTCAGAGTGGCTTTTCTCAGTTCCTATTCTCATTCGTCT

>5016_5016_2_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000360615_ZMIZ1_chr10_81036937_ENST00000478357_length(amino acids)=547AA_BP=498
MNVLSSSLPDLTMSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFGGANMPNLYPGAP
GAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVP
SYPGYPGSGTVTPAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSEL
SGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDE
STNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAE
RLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISSLVVLLVRRARPPAAAPTSEEPPERSPWETPHAAPSQLHELH

--------------------------------------------------------------
>5016_5016_3_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000422982_ZMIZ1_chr10_81036937_ENST00000478357_length(transcript)=5997nt_BP=1745nt
GCACTGCCTCTGGCACCTGGGGCAGCCGCGCCCGCGGAGTTTTCCGCCCGGCGCTGACGGCTGCTGCGCCCGCGGCTCCCCAGTGCCCCG
AGTGCCCCGCGGGCCCCGCGAGCGGGAGTGGGACCCAGCCCCTAGGCAGAACCCAGGCGCCGCGCCCGGGACGCCCGCGGAGAGAGCCAC
TCCCGCCCACGTCCCATTTCGCCCCTCGCGTCCGGAGTCCCCGTGGCCAGGTGTGTGTCTGGGGAAGAGACTTACAGAAGTGGAGTTGCT
GAGTCAAAGATCTAACCATGAGCTACCCTGGCTATCCCCCGCCCCCAGGTGGCTACCCACCAGCTGCACCAGGTGGTGGTCCCTGGGGAG
GTGCTGCCTACCCTCCTCCGCCCAGCATGCCCCCCATCGGGCTGGATAACGTGGCCACCTATGCGGGGCAGTTCAACCAGGACTATCTCT
CGGGAATGGCGGCCAACATGTCTGGGACATTTGGAGGAGCCAACATGCCCAACCTGTACCCTGGGGCCCCTGGGGCTGGCTACCCACCAG
TGCCCCCTGGCGGCTTTGGGCAGCCCCCCTCTGCCCAGCAGCCTGTTCCTCCCTATGGGATGTATCCACCCCCAGGAGGAAACCCACCCT
CCAGGATGCCCTCATATCCGCCATACCCAGGGGCCCCTGTGCCGGGCCAGCCCATGCCACCCCCCGGACAGCAGCCCCCAGGGGCCTACC
CTGGGCAGCCACCAGTGACCTACCCTGGTCAGCCTCCAGTGCCACTCCCTGGGCAGCAGCAGCCAGTGCCGAGCTACCCAGGATACCCGG
GGTCTGGGACTGTCACCCCCGCTGTGCCCCCAACCCAGTTTGGAAGCCGAGGCACCATCACTGATGCTCCCGGCTTTGACCCCCTGCGAG
ATGCCGAGGTCCTGCGGAAGGCCATGAAAGGCTTCGGGACGGATGAGCAGGCCATCATTGACTGCCTGGGGAGTCGCTCCAACAAGCAGC
GGCAGCAGATCCTACTTTCCTTCAAGACGGCTTACGGCAAGGATTTGATCAAAGATCTGAAATCTGAACTGTCAGGAAACTTTGAGAAGA
CAATCTTGGCTCTGATGAAGACCCCAGTCCTCTTTGACATTTATGAGATAAAGGAAGCCATCAAGGGGGTTGGCACTGATGAAGCCTGCC
TGATTGAGATCCTCGCTTCCCGCAGCAATGAGCACATCCGAGAATTAAACAGAGCCTACAAAGCAGAATTCAAAAAGACCCTGGAAGAGG
CCATTCGAAGCGACACATCAGGGCACTTCCAGCGGCTCCTCATCTCTCTCTCTCAGGGAAACCGTGATGAAAGCACAAACGTGGACATGT
CACTCGCCCAGAGAGATGCCCAGGAGCTGTATGCGGCCGGGGAGAACCGCCTGGGAACAGACGAGTCCAAGTTCAATGCGGTTCTGTGCT
CCCGGAGCCGGGCCCACCTGGTAGCAGTTTTCAATGAGTACCAGAGAATGACAGGCCGGGACATTGAGAAGAGCATCTGCCGGGAGATGT
CCGGGGACCTGGAGGAGGGCATGCTGGCCGTGGTGAAATGTCTCAAGAATACCCCAGCCTTCTTTGCGGAGAGGCTCAACAAGGCCATGA
GGGGGGCAGGAACAAAGGACCGGACCCTGATTCGCATCATGGTGTCTCGCAGCGAGACCGACCTCCTGGACATCAGATCAGAGTATAAGC
GGATGTACGGCAAGTCGCTGTACCACGACATCTCGAGCCTTGTTGTCCTCCTGGTGCGAAGAGCTCGGCCGCCTGCTGCTGCTCCGACAT
CAGAAGAGCCGCCAGAGCGATCCCCCTGGGAAACTCCCCATGCAGCCCCCTCTCAGCTCCATGAGCTCCATGAAACCCACTCTGTCGCAC
AGTGATGGGTCGTTCCCCTATGACTCTGTCCCTTGGCAGCAGAACACCAACCAGCCTCCCGGCTCCCTTTCCGTGGTCACCACGGTTTGG
GGAGTAACCAACACATCCCAGAGCCAGGTCCTTGGGAACCCTATGGCCAATGCCAACAACCCCATGAATCCAGGCGGCAACCCCATGGCG
TCGGGCATGACCACCAGCAACCCAGGCCTCAACTCCCCACAGTTTGCGGGGCAGCAGCAGCAGTTCTCAGCCAAGGCTGGCCCCGCTCAG
CCCTACATCCAGCAGAGCATGTATGGCCGGCCCAACTACCCCGGCAGCGGGGGCTTTGGGGCCAGTTACCCTGGGGGTCCTAACGCCCCC
GCAGGCATGGGCATCCCTCCGCACACCAGGCCGCCTGCTGACTTCACTCAGCCCGCGGCAGCCGCTGCAGCAGCGGCAGTGGCAGCAGCA
GCAGCCACAGCTACAGCCACAGCCACGGCCACTGTGGCAGCCCTGCAGGAGACACAGAACAAGGATATAAACCAGTATGGACCGGTCTGT
TCCTCTTTCCAGATGGGTCCCACCCAGGCGTATAACAGCCAATTCATGAACCAGCCCGGGCCGCGGGGGCCTGCCTCCATGGGGGGCAGC
ATGAACCCCGCGAGCATGGCGGCTGGCATGACGCCCTCGGGGATGAGCGGCCCTCCCATGGGCATGAACCAGCCCCGGCCGCCCGGCATC
AGCCCCTTTGGCACACACGGGCAGCGGATGCCCCAGCAGACCTACCCGGGCCCCCGGCCCCAGTCCCTTCCTATTCAGAACATAAAGAGG
CCATACCCTGGAGAGGTGAGTGCAGCAGTGGGAGCCTGGGAGGTGGGAACTGGGACACCTGGGCTTGAAGACATGGGCCGTGGGTACGGC
TTTGGAAGGGGTGTGGCTTGGACTCCAGCACACTTGGACAAAGAGGCAGGGGCTTAGGGGTCAGGTGCTCCTGGGTTTGAGACCTGGTTC
TGCTGTTTCCCAACTGAAAGACCTCGAGCCAGTCACCCTGCCTCCTAGGGCTGCTTGAGGGACTTGAGGAGGTGTCCGTGAAGTGCTTGG
CCCTGGGCTGGCATGTGCCGCCACTCAGCAAGCAGCAGTTCCTCTTACTGTAGTGACTCTTGTCTTGGCTCAGCCACTAACTGGGTGACC
TGGGTTTAGTTCCTCCTGCCCACATGAGAGCTTCCCCAACTCCTCTCCAAGAAAGAGAGCTGAGACAAAATGCTTCCAGTCTATAAGGGC
TGACCCGTCCGGGAAGTGACTGGAAGGCAGGCAGCGTGTTTCCAGTCTGTAAGGATTGACCTGTTGGGGAAGTGACTGGAAGGCAGAGAG
CGTGTTTCCAATCTATAAGGACTGACCCGTTGGGGAAGTGACTGGAAGGCCGGCAGCTGTTTCCAGTCTATAAGGACTGACCCGTCAGGG
AAGTGACTGGAAGGCAGACAGCGTGTTTCTTAGCTCTTGTTTCCATCCACACTTGGTCACTGTATAGGAAGTGGCACTGCCTCTTGGGCT
GCACAGCCAGCTCAGCCAAGGTGTTGGGGAAGATTTGGGGAAGTAAAACCCACACCTCCTGCCCTCTGGGAAGTGAGGTTTTAGCAGGAA
AGAAAAGTTTTTAGCAGAGACTCACCAGGGAATGAAGCATAGCAGACTGCACAGAACTCAATATGAGTCAGAGAAGGCAGGCTTCCTGGA
GGGTGTGTCACAAGTAAATCCTCAGAAAATGATGCTGGCAGCAGCTGGCCCATCTGGGTACCCAGGTAAGGATTTAGTTTACCTGCAGAA
GACGTAGGGACGTGGCTCTGCAGATGCCCCTCGTGAAGCCCTGGTTGCTCCCCACGACCAAGCCCCTTTTTGAGCAGGGTGTGCCCAGCT
CTCTGCCTGCCTCCCTCCCAGCTTGCATGCCCACTCTCAGAGCAGTTTTCTCCTCCTAGCTCCTCTCAGCTCTGTGGCCTTCACCTTGGG
TTCACAGCGGCTTTAGATTCCAAAGACCTTAAGTTCCTTGAAGATCTGCACATTTCCCCTCAGTATCCACCTTAGGATGGGCGGGGAGGC
TTGGCAACAAGTGGAGGTATTCTGAGTTCAGGAGGGGAGAGAGAGGGGGGGGGGTCAGGGGCTTCCTCATGCATCCAAGAAGCTGGATCA
AGCCCCAACCCTCCACCTGGTGGACACTAGTTCAGGGAGGGGCCAGAGAAGGACCATTGGCTCCTGGGTCCTGAGTTTGGGGGAGCCTCA
AGCTATTGGCACCTCTCCTGGCACTCAGGCCCCATGCAGTTTCTAGGCCTTTTCTCAGCCACCCTGTGCTCAAAATCCCAGTGTCCCACT
GGCTGTGCTGGGGGTGCATCTGTTAGCCCACGCCAAAGGAGGCAATCTCGGATGAGGCTTCAGCAGAATTCCTGGTCATTGGTGTCACCC
CTGCACCTGCACCTGTGCCATGCTTATGGCTCTTGCCTGCCTAAAGAGAGCACACCAAAGGCTCTCCATATTTTTACTAAATTAATCATC
CTTTTCATAGAGTGCTGCTGCTACCCAGCTACAGCACTGGGTGGTCACAGCCTATGCGGCCTGATCCTGTCTGGAAGACTGGCCTTCCTT
CCCCTTGCCATGGCTTGTTCATACAATATTTGAATTGTTGGAGCCTTAGGACAGGGGTTGGGTCATCTGGTCCCACAGAGGACTCTCTTC
TCTAGCTTGGTGGGCAGGTAGGCACCAGCTACGTCTTCTATACCTCCTGTGGTGGGTGCCTCACTGTCACCCAGAGCAGCCACCATGTTG
CAACAACGTGAGTTGTAGATTCTTCCACACTGACACTTTCTGACATTTATCCCTAAGTCCATCATTCGTTTGTTGAGCAAGTATTAAGGG
TATTTTCCCAGGCACTGGGGCACAGCCACCAACAGGACCTCTGGGCAAGAGAGACACTCAGATGGGGAAGAAGAAACCACTGACTCACAG
GATGTCATGTGGCCGTGAGGGTCACCTGATTTTCCAGACAGGGAAGGTGGCTGGAGGGTGGTGCTCTCTCCTCTTCTCTAAATTGTCTGT
CCCGGGAGAAGTTGTCTTGTTCCTTCACCAACCTGGCTCTCCCACCTCCTGCACAGGTGGCAGGTTGTCGATGGCCCAGAACTGAACACT
AGGTGTGTGTTCTGCTCTGAGGGGAGTACGAGGACAATGCCACCCAAGTTCAGCCTTGGAATGCAGGGGCACAGGGGGCTCCTTTCTGGA
ATTGCATCCTGTTGACTGTGTTCCTCTGTCACATTGGGGTACACATTGGGGAGCACAGCCCTAACCCAGGCACCAGGAGAGACACAAAGG
TCGGGGGAGTTAGAATCAGGCCCCTCATAATGGTGTGAGCAAGAGGCTCTGAAAGTGTCCCTGGAGTTCAGGGGCACATGTGCTCCAGGA
AGAACGGCCTCAAGGGGAGGTGGCCTATGATCTGGACAGGCAGAACAAAATGCCCCTGGATGTCAGGACGAGAAGGGGCCCAAAGCATTA
TCTGGTTTTGTGGGTGGGAAACAGCAGGAGCAAATGAGGAGAGGCGGGCCCCATCCCGTTGTTCAGGTGACCTGGCTATGTGACGTTGGC
AACATTGAACGTGTTTCCCCTCTCCTTTCTCTCCCACCACAGCCCAACTATGGAAACCAGCAATATGGACCAAACAGCCAGTTCCCCACC
CAGCCAGGCCAGTACCCAGCCCCCAACCCCCCGAGGCCACTCACCTCCCCCAACTACCCAGGACAGAGGATGCCCAGCCAGCCGAGCTCC
GGGCAGTACCCGCCCCCCACGGTCAACATGGGGCAGTATTACAAGGTGAGTCCCAGCCTCGCCACCACCCACGGGGCCCCTTCCCTCCTA
ACCACCTCACTCCCCTAACTCCACCGGGATCACTCTGACCCTGCGTGTGTTTGCCCCAAGGACAGCGAGGGGTGGGTGATTTCTGAACGT
CCCCATGTGTTCAGGGCGAAGTTCGGTGGCCAGAATGTCAGAGTGGCTTTTCTCAGTTCCTATTCTCATTCGTCTCGGATGATGGTTTTT

>5016_5016_3_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000422982_ZMIZ1_chr10_81036937_ENST00000478357_length(amino acids)=535AA_BP=486
MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFGGANMPNLYPGAPGAGYPPVPPGGF
GQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVT
PAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALM
KTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRD
AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTK

--------------------------------------------------------------
>5016_5016_4_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000438331_ZMIZ1_chr10_81036937_ENST00000334512_length(transcript)=8635nt_BP=1941nt
GCACTGCCTCTGGCACCTGGGGCAGCCGCGCCCGCGGAGTTTTCCGCCCGGCGCTGACGGCTGCTGCGCCCGCGGCTCCCCAGTGCCCCG
AGTGCCCCGCGGGCCCCGCGAGCGGGAGTGGGACCCAGCCCCTAGGCAGAACCCAGGCGCCGCGCCCGGGACGCCCGCGGAGAGAGCCAC
TCCCGCCCACGTCCCATTTCGCCCCTCGCGTCCGGAGTCCCCGTGGCCAGGGATTATTGGACCTGCCTGGTTTAAACTATTGTCTTAGTT
AATTTTGTGCTGCTCTAACAAAATATCACAGACTGAGTAATTTATAAGCAATAGTAGCTTATTTGGCTCACAGTTCTGGAGGCTGAGAAG
ATCGTGAGGCTGCATCTGGCAAGGGCCTTCTTGCTGCTTCATAACATGGCAGAAGACATCATGCGGGTGTGTGTCTGGGGAAGAGACTTA
CAGAAGTGGAGTTGCTGAGTCAAAGATCTAACCATGAGCTACCCTGGCTATCCCCCGCCCCCAGGTGGCTACCCACCAGCTGCACCAGGT
GGTGGTCCCTGGGGAGGTGCTGCCTACCCTCCTCCGCCCAGCATGCCCCCCATCGGGCTGGATAACGTGGCCACCTATGCGGGGCAGTTC
AACCAGGACTATCTCTCGGGAATGGCGGCCAACATGTCTGGGACATTTGGAGGAGCCAACATGCCCAACCTGTACCCTGGGGCCCCTGGG
GCTGGCTACCCACCAGTGCCCCCTGGCGGCTTTGGGCAGCCCCCCTCTGCCCAGCAGCCTGTTCCTCCCTATGGGATGTATCCACCCCCA
GGAGGAAACCCACCCTCCAGGATGCCCTCATATCCGCCATACCCAGGGGCCCCTGTGCCGGGCCAGCCCATGCCACCCCCCGGACAGCAG
CCCCCAGGGGCCTACCCTGGGCAGCCACCAGTGACCTACCCTGGTCAGCCTCCAGTGCCACTCCCTGGGCAGCAGCAGCCAGTGCCGAGC
TACCCAGGATACCCGGGGTCTGGGACTGTCACCCCCGCTGTGCCCCCAACCCAGTTTGGAAGCCGAGGCACCATCACTGATGCTCCCGGC
TTTGACCCCCTGCGAGATGCCGAGGTCCTGCGGAAGGCCATGAAAGGCTTCGGGACGGATGAGCAGGCCATCATTGACTGCCTGGGGAGT
CGCTCCAACAAGCAGCGGCAGCAGATCCTACTTTCCTTCAAGACGGCTTACGGCAAGGATTTGATCAAAGATCTGAAATCTGAACTGTCA
GGAAACTTTGAGAAGACAATCTTGGCTCTGATGAAGACCCCAGTCCTCTTTGACATTTATGAGATAAAGGAAGCCATCAAGGGGGTTGGC
ACTGATGAAGCCTGCCTGATTGAGATCCTCGCTTCCCGCAGCAATGAGCACATCCGAGAATTAAACAGAGCCTACAAAGCAGAATTCAAA
AAGACCCTGGAAGAGGCCATTCGAAGCGACACATCAGGGCACTTCCAGCGGCTCCTCATCTCTCTCTCTCAGGGAAACCGTGATGAAAGC
ACAAACGTGGACATGTCACTCGCCCAGAGAGATGCCCAGGAGCTGTATGCGGCCGGGGAGAACCGCCTGGGAACAGACGAGTCCAAGTTC
AATGCGGTTCTGTGCTCCCGGAGCCGGGCCCACCTGGTAGCAGTTTTCAATGAGTACCAGAGAATGACAGGCCGGGACATTGAGAAGAGC
ATCTGCCGGGAGATGTCCGGGGACCTGGAGGAGGGCATGCTGGCCGTGGTGAAATGTCTCAAGAATACCCCAGCCTTCTTTGCGGAGAGG
CTCAACAAGGCCATGAGGGGGGCAGGAACAAAGGACCGGACCCTGATTCGCATCATGGTGTCTCGCAGCGAGACCGACCTCCTGGACATC
AGATCAGAGTATAAGCGGATGTACGGCAAGTCGCTGTACCACGACATCTCGCCTTGTTGTCCTCCTGGTGCGAAGAGCTCGGCCGCCTGC
TGCTGCTCCGACATCAGAAGAGCCGCCAGAGCGATCCCCCTGGGAAACTCCCCATGCAGCCCCCTCTCAGCTCCATGAGCTCCATGAAAC
CCACTCTGTCGCACAGTGATGGGTCGTTCCCCTATGACTCTGTCCCTTGGCAGCAGAACACCAACCAGCCTCCCGGCTCCCTTTCCGTGG
TCACCACGGTTTGGGGAGTAACCAACACATCCCAGAGCCAGGTCCTTGGGAACCCTATGGCCAATGCCAACAACCCCATGAATCCAGGCG
GCAACCCCATGGCGTCGGGCATGACCACCAGCAACCCAGGCCTCAACTCCCCACAGTTTGCGGGGCAGCAGCAGCAGTTCTCAGCCAAGG
CTGGCCCCGCTCAGCCCTACATCCAGCAGAGCATGTATGGCCGGCCCAACTACCCCGGCAGCGGGGGCTTTGGGGCCAGTTACCCTGGGG
GTCCTAACGCCCCCGCAGGCATGGGCATCCCTCCGCACACCAGGCCGCCTGCTGACTTCACTCAGCCCGCGGCAGCCGCTGCAGCAGCGG
CAGTGGCAGCAGCAGCAGCCACAGCTACAGCCACAGCCACGGCCACTGTGGCAGCCCTGCAGGAGACACAGAACAAGGATATAAACCAGT
ATGGACCGATGGGTCCCACCCAGGCGTATAACAGCCAATTCATGAACCAGCCCGGGCCGCGGGGGCCTGCCTCCATGGGGGGCAGCATGA
ACCCCGCGAGCATGGCGGCTGGCATGACGCCCTCGGGGATGAGCGGCCCTCCCATGGGCATGAACCAGCCCCGGCCGCCCGGCATCAGCC
CCTTTGGCACACACGGGCAGCGGATGCCCCAGCAGACCTACCCGGGCCCCCGGCCCCAGTCCCTTCCTATTCAGAACATAAAGAGGCCAT
ACCCTGGAGAGCCCAACTATGGAAACCAGCAATATGGACCAAACAGCCAGTTCCCCACCCAGCCAGGCCAGTACCCAGCCCCCAACCCCC
CGAGGCCACTCACCTCCCCCAACTACCCAGGACAGAGGATGCCCAGCCAGCCGAGCTCCGGGCAGTACCCGCCCCCCACGGTCAACATGG
GGCAGTATTACAAGCCAGAACAGTTTAATGGACAAAATAACACGTTCTCGGGAAGCAGCTACAGTAACTACAGCCAAGGGAATGTCAACA
GGCCTCCCAGGCCGGTTCCTGTGGCAAATTACCCCCACTCACCTGTTCCAGGGAACCCCACACCCCCCATGACCCCTGGGAGCAGCATCC
CTCCATACCTGTCCCCCAGCCAAGACGTCAAACCACCCTTCCCGCCTGACATCAAGCCAAATATGAGCGCTCTGCCACCACCCCCAGCCA
ACCACAATGACGAGCTGCGGCTCACATTCCCTGTGCGGGATGGCGTGGTGCTGGAGCCCTTCCGCCTGGAGCACAACCTGGCGGTCAGCA
ACCATGTGTTCCACCTGCGGCCCACGGTCCACCAGACGCTGATGTGGAGGTCTGACCTGGAGCTGCAGTTCAAGTGCTACCACCACGAGG
ACCGGCAGATGAACACCAACTGGCCCGCCTCGGTGCAGGTCAGCGTGAACGCCACGCCCCTCACCATTGAGCGCGGCGACAACAAGACCT
CCCACAAGCCCCTGCACCTGAAGCACGTGTGCCAGCCGGGCCGCAACACCATCCAGATCACCGTCACGGCCTGCTGCTGCTCCCACCTCT
TCGTGCTGCAGCTGGTACACCGGCCCTCCGTCCGCTCTGTGCTGCAAGGACTCCTCAAGAAGCGCCTCCTGCCCGCAGAGCACTGTATCA
CGAAAATCAAGCGGAATTTCAGCAGCGTGGCTGCCTCCTCGGGCAACACGACCCTCAACGGGGAGGATGGGGTGGAGCAGACGGCCATCA
AGGTGTCTCTGAAGTGCCCCATCACATTCCGGCGCATCCAGCTGCCTGCTCGAGGACACGATTGCAAGCATGTGCAGTGCTTTGATCTGG
AGTCATACCTGCAGCTGAATTGCGAGAGAGGGACCTGGAGGTGTCCTGTGTGCAATAAAACCGCTCTGCTGGAGGGCCTGGAGGTGGATC
AGTACATGTGGGGAATCCTGAATGCCATCCAACACTCCGAGTTTGAAGAGGTCACCATCGATCCCACGTGCAGCTGGCGGCCGGTGCCCA
TCAAGTCGGACTTACACATCAAGGACGACCCTGATGGCATCCCCTCCAAGCGGTTCAAGACCATGAGTCCCAGCCAGATGATCATGCCCA
ATGTCATGGAGATGATCGCAGCCCTGGGCCCCGGCCCGTCCCCCTATCCCCTCCCGCCTCCCCCAGGGGGCACCAACTCCAACGACTACA
GCAGCCAAGGCAACAACTACCAAGGCCATGGCAACTTTGACTTCCCCCACGGGAACCCTGGAGGGACATCCATGAATGACTTCATGCACG
GGCCCCCCCAGCTCTCCCACCCCCCGGACATGCCCAACAACATGGCCGCCCTCGAGAAACCCCTCAGCCACCCCATGCAGGAAACTATGC
CACACGCTGGCAGCTCTGACCAGCCCCACCCCTCCATACAACAAGGTTTGCACGTACCACACCCCAGCAGCCAGTCAGGGCCTCCATTAC
ATCACAGTGGGGCTCCTCCTCCTCCTCCTTCCCAGCCTCCCCGGCAGCCGCCACAGGCCGCTCCCAGCAGCCATCCACACAGCGACCTGA
CCTTTAACCCCTCCTCAGCCTTAGAGGGTCAGGCCGGAGCGCAGGGAGCGTCCGACATGCCGGAGCCTTCGCTGGATCTCCTTCCCGAAC
TCACAAATCCTGACGAGCTCCTGTCTTATCTGGACCCCCCCGACCTGCCGAGCAATAGTAACGATGACCTCCTGTCTCTATTTGAGAACA
ACTGAGGGCCACCCGGTCGGGGCCATCCCTCCACACTCTGCATCCTACCCCACCTACCCAACACACTTTTCCACCTGGGAGCCTGTGCCC
TCAGACCGCCCCGCACCAGAGCCACGGGCTGTGGGGCGGGGAGCCCTCCCCCGCTGCAGCCCTCTCAGAACAGAGGGGTAGGGAGGGTGC
ACCAGTGCACCAGGAAGGCTGTGTGGGTCTGGAGCCCACGTCCCACCTCCACACCCTTGGCTTGGGCCCATGCCCAGCGCAGGCCTGAAG
ACCACCCTCCCGAGAGGAACCAGCCCGGTAAGAGGGCACACGCTGATGCGGCTTCCCGGTCCCTCCGCGTGTGCCGATTCCAGATGACCT
TCCAGTGTCCCCAAGGTTCTTCCATCTTCTAGACTGTAACCCTGCCTCCCTGCTTCCTGGTCCAGAGCCTCCCTCCAGTGACTGTGGAGC
CTGAGAAGGCCCCCGGGCCCCAGCATGGGCCCCGAGCCTTGGAGGAGCACTGGCAGTTGGTGGCAGTGAGACCAGCCCACCCACCACCAC
CCACCACAGAAAAGCACAAACCTCTGGGAAAGACAACGTCTCTCGGGGGCCAGGGGTCATCGGTTTGACCCCTGACCTATAAGCCAAGAT
ACCCCATAAACACACTCAGAAAGCAGAGAAAAAGGACAAGAGTCTGTGTTTGAGAGGGGGTCTGCCATTCCTGCTTGGGGACTGGTGGGG
AAGAGGGCCAGGACATCTTCTGAGCCAGGACGTCCCTGAGGCTCCACCTCCAAGCTCAGACAGGGCCCAGGCTTGGGGAACAGAGAGAGC
AGGTGTACACCCAACCAAAGTGATTGTGCCCTTGGTTGGGGGGCGCGGGCATATAACCTGTCAGAAGCAAACAGGAGCGGCAACTTCTAA
CTTTGCTCCAAGCCACTCTCTTTTTAAACAGCAACAATTTAAAGCTATGAAGTCACCTGGAGAAAAGGAACGTTGCTCTTGGACAGCAAG
CAAACCATTTCTCTCCGTCTGTTCTGTTTTTCTCCTAGTCCCTCTCCTGCCACCTCTCCAAGACTTCCGTGGGACACCCACTTCCCTCTG
TCCTAGTTCTCTTTGTCCAATCAGATGGCAAGGGCAGTGCGTGGAAAGGCCGGGGAGGTGCAGAAACCAGAGCCCAGGGCAATGGTGTCT
GTCCAGCCCCTCCCTCTGTCCCTGTGCTCCAAGCTGCCCCCGGCTGCAGCCCAGGCCATGGACATGTGCACCAGTATGTACCTGCAGGCA
TGGGGGGGAGGGGGGCGTGTTTCTGGGCCTGCCCCAGACACTGCCCTTGGCTGCCAGCCTACCCTGCCTGCACTCCTCCACCATCACAAT
CTCACCCAAACTCCTGCTCACTCAAGCAAAAGCAGCCTCTGGCCTTCCCTCCACCGCTTTGCTCCATCTGGCTTACCACTCTCCAGGGCC
TCCTGGGGAGCCTGTCCTGTGTTCACTTTGTTTCAGGCTGGTCTGTGCCCCGTGAGCCACATGGCCTAGGGTGATGCCAGGTTGTCCCGT
CACTGGGGTCCCATCTGTAAATTCTTTGCGCCCTTCCCGGCTGCTGCCTGGGGCCCTTTCCTGCTCTCCCGTCCGCTGTGGGTGGTCCCC
AGCTCTCCTCTGTGGGTTTTACCGGAAAGGTGGCCCCAGCTGTTGACTTCCAGTCACTGTCCCAGACGGCACAAGGTTTTCTGTAGGAAA
GCTGCCATTGCCCCGGCCCCTTTTCTTCCTTTGTCCCGTTGTCGAGGTTTTTTCAAATAGCGTGTTGTTCAGTATGCAAATCAATTATTT
TAAGAATCGCTTTTGTAAATATCTTTGTGAATATTTTAGTATCGTCTTTGATAATATTCAACATTTTCATGACCTGGTTATAGCCTTTGC
TGGTGTTTTTAAAATACCTGGACTCAATGACAAAGACCGAGTCTTCTTTTTTTTTAAACAAAAACAAAAAAAGCAACCAGGGCTATTTGT
ACAGTTGAAGGGGTGAACAGAATGGGCGGCTGTGCTGGGAGTTGGAAGACCGGGCAGCCCGCTATTTAGAGCCATCCCTCAGTCAGCTGG
CAGGGACAAGCCAACGCCAGGTAGCATGTGGCCACCCTTGCCCAGTGTCTGTGGCCTGGCAAGTGGCCACGCCCTGTGTCAGACCATCTG
GGAATTAAGCTCCAGACAGACTTACAGATGCCTTCCTTAGGAGTTCTTGCTTCTTGCGTTGATACTTTGCCCCAGAAAGGCCTGGGATTC
ATTCTGGTTCTTATCAGGGTGTGTCCACACTCTGCTCACAGGTGGATCCACGGCTTTCCAGTGCGGAGAGTCGAGATGCTCCCTGCAGCC
CAGGCCCCGGGCACCTCCTGCAACCATCTCTGGGCTCAGCACCTGAGGCGGGTTTCCTGGGTCCCCTCTCCAGCAAGCCTCCACCAGCAA
GCTCGGCCCAGAGCTTCCCTTCCGGCTGGCTCTGAACCGTGCGTGGTGCCTACAGCCTGCAGTCTGGAGACAAGCTCTTCCGGAGTGCTC
TGGGAGCCAGGCCAGGGTGTGAGGGAGGTGCAGAGGCATCCGGGGCGGGAGCAAGCCCCAGGTTGTGACAGGTGCAGGTAGACAACGCCC
ATAAACAGAGATGGTCCTGAACTCTGGAGAGATCCTTCCCTGATCCTTTCGGACGACTACTTGGAGCCATAAGTAACCTCAGCAAAAACG
AGGCCTCTGCAAGCCACTTTTCCATGCCAAGCATCCACCCGGCCCACAGGCATGTTTCTGCCGCCACTCCGCAAGATGGACAGGGAGCCA
GCAGGCAGGCGGGAAGGGCCAAGTACAGGCAATCACCCCCATCTTCTTGGTTTGAAGCTTTATCCATGTATCATGTTCCGTGTAGCCATT
TTATTTTTTAAGAAACTGCTAATACTTTCTCCCTAATGGAAGCCCTGATCCCCCAGAGAGCTACAGGTCTGCTCCCGACGGGCCTCGGGC
CTGACCCGTCCACACAGGGCCGTGTCAACAGCAGCGACTCAAGGGACGTGTGTACATATGTAAATGAGAAATAGAGACGTGTCAACAGAT
GCATTCATTTCTCTTGGAATGTGTATTGTTTTTATTTTGCGAAACAAAACAAAACAAAAAAAAAAGCTTGGAACTCCATCACGTGGAAAA
ACTAGATCCTGTTGGTTATAGCATTTGTGAGTTCTCCACGTCTGTCTCTCTCGCTCATGTAATATACTCTGACCCTGAGTGGAAAGGGGT
TTTTGTTCTGTTTTTATTTTACCTACATGTACTATTTAGCTTCAGTGTACTAGTCCTGCCACCTGTGTATTTTTAGGGTGCTATGGAAAT
AATGAAAAGAAACGGGGATTTCAGAAGAAAATTGTAACCAAATTCATACTTTGTATAATTTTTGATATCATGATCACAGGTGATTCACAC
GTACACACATAAACACACCCACCAGTGCAGCCTGAAGTAACTCCCACAGAAACCATCATCGTCTTTGTACATCGTATGTACAATGCAATC
ATTTCATACTTTAAACTGGTCAAAAAACTAATTGTGATTTCTAGTCTTGCAAAGCTGTATGTAGTTAGATGATGTGACAACCTCTAATAT
TTATCTAATAAATATGTATTCAGATGAAACCTGTATATTAGGTGTTCATGTGGTTATTTTGTATTTAAAGATCAAATTATTTGACTATTG

>5016_5016_4_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000438331_ZMIZ1_chr10_81036937_ENST00000334512_length(amino acids)=973AA_BP=1
MLSSWCEELGRLLLLRHQKSRQSDPPGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQSQVLGN
PMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPA
DFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPP
MGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQP
SSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDI
KPNMSALPPPPANHNDELRLTFPVRDGVVLEPFRLEHNLAVSNHVFHLRPTVHQTLMWRSDLELQFKCYHHEDRQMNTNWPASVQVSVNA
TPLTIERGDNKTSHKPLHLKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSVAASSGNTT
LNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQCFDLESYLQLNCERGTWRCPVCNKTALLEGLEVDQYMWGILNAIQHSEFEEV
TIDPTCSWRPVPIKSDLHIKDDPDGIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHG
NPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPP

--------------------------------------------------------------
>5016_5016_5_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000537102_ZMIZ1_chr10_81036937_ENST00000334512_length(transcript)=8694nt_BP=2000nt
ACCTGGGGCAGCCGCGCCCGCGGAGTTTTCCGCCCGGCGCTGACGGCTGCTGCGCCCGCGGCTCCCCAGTGCCCCGAGTGCCCCGCGGGC
CCCGCGAGCGGGAGTGGGACCCAGCCCCTAGGCAGAACCCAGGCGCCGCGCCCGGGACGCCCGCGGAGAGAGCCACTCCCGCCCACGTCC
CATTTCGCCCCTCGCGTCCGGAGTCCCCGTGGCCAGGTGTGTGTCTGGGGAAGAGACTTACAGAAGTGGAGTTGCTGAGTCAAAGATCTA
ACCATGAGCTACCCTGGCTATCCCCCGCCCCCAGGTGGCTACCCACCAGCTGCACCAGGTTGGCTGGCACTGGCCTGGGTTCTCTCTCTA
TAGTAGAAATCCTGCCATCCAGATCCTGCCACTGCCACCTTTGCTAGCACAGCTGAGCAGCCTCTGAGCAGCAAGAGAGGAGGAGGCAGG
AAATTTAGGGAAGGTTCTTCCTGGAGGGTCTGGAGCCCTGGAGATGAAGAGCCGATCCGAAGCTGCCATGTAGAGGAAAGCATCTAACAG
GCCAGAGGCCCCATGATGATGTCGAATGCCCATCGGGCACCCAGCTGAGCCCTGCAGGTGGTGGTCCCTGGGGAGGTGCTGCCTACCCTC
CTCCGCCCAGCATGCCCCCCATCGGGCTGGATAACGTGGCCACCTATGCGGGGCAGTTCAACCAGGACTATCTCTCGGGAATGGCGGCCA
ACATGTCTGGGACATTTGGAGGAGCCAACATGCCCAACCTGTACCCTGGGGCCCCTGGGGCTGGCTACCCACCAGTGCCCCCTGGCGGCT
TTGGGCAGCCCCCCTCTGCCCAGCAGCCTGTTCCTCCCTATGGGATGTATCCACCCCCAGGAGGAAACCCACCCTCCAGGATGCCCTCAT
ATCCGCCATACCCAGGGGCCCCTGTGCCGGGCCAGCCCATGCCACCCCCCGGACAGCAGCCCCCAGGGGCCTACCCTGGGCAGCCACCAG
TGACCTACCCTGGTCAGCCTCCAGTGCCACTCCCTGGGCAGCAGCAGCCAGTGCCGAGCTACCCAGGATACCCGGGGTCTGGGACTGTCA
CCCCCGCTGTGCCCCCAACCCAGTTTGGAAGCCGAGGCACCATCACTGATGCTCCCGGCTTTGACCCCCTGCGAGATGCCGAGGTCCTGC
GGAAGGCCATGAAAGGCTTCGGGACGGATGAGCAGGCCATCATTGACTGCCTGGGGAGTCGCTCCAACAAGCAGCGGCAGCAGATCCTAC
TTTCCTTCAAGACGGCTTACGGCAAGGATTTGATCAAAGATCTGAAATCTGAACTGTCAGGAAACTTTGAGAAGACAATCTTGGCTCTGA
TGAAGACCCCAGTCCTCTTTGACATTTATGAGATAAAGGAAGCCATCAAGGGGGTTGGCACTGATGAAGCCTGCCTGATTGAGATCCTCG
CTTCCCGCAGCAATGAGCACATCCGAGAATTAAACAGAGCCTACAAAGCAGAATTCAAAAAGACCCTGGAAGAGGCCATTCGAAGCGACA
CATCAGGGCACTTCCAGCGGCTCCTCATCTCTCTCTCTCAGGGAAACCGTGATGAAAGCACAAACGTGGACATGTCACTCGCCCAGAGAG
ATGCCCAGGAGCTGTATGCGGCCGGGGAGAACCGCCTGGGAACAGACGAGTCCAAGTTCAATGCGGTTCTGTGCTCCCGGAGCCGGGCCC
ACCTGGTAGCAGTTTTCAATGAGTACCAGAGAATGACAGGCCGGGACATTGAGAAGAGCATCTGCCGGGAGATGTCCGGGGACCTGGAGG
AGGGCATGCTGGCCGTGGTGAAATGTCTCAAGAATACCCCAGCCTTCTTTGCGGAGAGGCTCAACAAGGCCATGAGGGGGGCAGGAACAA
AGGACCGGACCCTGATTCGCATCATGGTGTCTCGCAGCGAGACCGACCTCCTGGACATCAGATCAGAGTATAAGCGGATGTACGGCAAGT
CGCTGTACCACGACATCTCGCCTTGTTGTCCTCCTGGTGCGAAGAGCTCGGCCGCCTGCTGCTGCTCCGACATCAGAAGAGCCGCCAGAG
CGATCCCCCTGGGAAACTCCCCATGCAGCCCCCTCTCAGCTCCATGAGCTCCATGAAACCCACTCTGTCGCACAGTGATGGGTCGTTCCC
CTATGACTCTGTCCCTTGGCAGCAGAACACCAACCAGCCTCCCGGCTCCCTTTCCGTGGTCACCACGGTTTGGGGAGTAACCAACACATC
CCAGAGCCAGGTCCTTGGGAACCCTATGGCCAATGCCAACAACCCCATGAATCCAGGCGGCAACCCCATGGCGTCGGGCATGACCACCAG
CAACCCAGGCCTCAACTCCCCACAGTTTGCGGGGCAGCAGCAGCAGTTCTCAGCCAAGGCTGGCCCCGCTCAGCCCTACATCCAGCAGAG
CATGTATGGCCGGCCCAACTACCCCGGCAGCGGGGGCTTTGGGGCCAGTTACCCTGGGGGTCCTAACGCCCCCGCAGGCATGGGCATCCC
TCCGCACACCAGGCCGCCTGCTGACTTCACTCAGCCCGCGGCAGCCGCTGCAGCAGCGGCAGTGGCAGCAGCAGCAGCCACAGCTACAGC
CACAGCCACGGCCACTGTGGCAGCCCTGCAGGAGACACAGAACAAGGATATAAACCAGTATGGACCGATGGGTCCCACCCAGGCGTATAA
CAGCCAATTCATGAACCAGCCCGGGCCGCGGGGGCCTGCCTCCATGGGGGGCAGCATGAACCCCGCGAGCATGGCGGCTGGCATGACGCC
CTCGGGGATGAGCGGCCCTCCCATGGGCATGAACCAGCCCCGGCCGCCCGGCATCAGCCCCTTTGGCACACACGGGCAGCGGATGCCCCA
GCAGACCTACCCGGGCCCCCGGCCCCAGTCCCTTCCTATTCAGAACATAAAGAGGCCATACCCTGGAGAGCCCAACTATGGAAACCAGCA
ATATGGACCAAACAGCCAGTTCCCCACCCAGCCAGGCCAGTACCCAGCCCCCAACCCCCCGAGGCCACTCACCTCCCCCAACTACCCAGG
ACAGAGGATGCCCAGCCAGCCGAGCTCCGGGCAGTACCCGCCCCCCACGGTCAACATGGGGCAGTATTACAAGCCAGAACAGTTTAATGG
ACAAAATAACACGTTCTCGGGAAGCAGCTACAGTAACTACAGCCAAGGGAATGTCAACAGGCCTCCCAGGCCGGTTCCTGTGGCAAATTA
CCCCCACTCACCTGTTCCAGGGAACCCCACACCCCCCATGACCCCTGGGAGCAGCATCCCTCCATACCTGTCCCCCAGCCAAGACGTCAA
ACCACCCTTCCCGCCTGACATCAAGCCAAATATGAGCGCTCTGCCACCACCCCCAGCCAACCACAATGACGAGCTGCGGCTCACATTCCC
TGTGCGGGATGGCGTGGTGCTGGAGCCCTTCCGCCTGGAGCACAACCTGGCGGTCAGCAACCATGTGTTCCACCTGCGGCCCACGGTCCA
CCAGACGCTGATGTGGAGGTCTGACCTGGAGCTGCAGTTCAAGTGCTACCACCACGAGGACCGGCAGATGAACACCAACTGGCCCGCCTC
GGTGCAGGTCAGCGTGAACGCCACGCCCCTCACCATTGAGCGCGGCGACAACAAGACCTCCCACAAGCCCCTGCACCTGAAGCACGTGTG
CCAGCCGGGCCGCAACACCATCCAGATCACCGTCACGGCCTGCTGCTGCTCCCACCTCTTCGTGCTGCAGCTGGTACACCGGCCCTCCGT
CCGCTCTGTGCTGCAAGGACTCCTCAAGAAGCGCCTCCTGCCCGCAGAGCACTGTATCACGAAAATCAAGCGGAATTTCAGCAGCGTGGC
TGCCTCCTCGGGCAACACGACCCTCAACGGGGAGGATGGGGTGGAGCAGACGGCCATCAAGGTGTCTCTGAAGTGCCCCATCACATTCCG
GCGCATCCAGCTGCCTGCTCGAGGACACGATTGCAAGCATGTGCAGTGCTTTGATCTGGAGTCATACCTGCAGCTGAATTGCGAGAGAGG
GACCTGGAGGTGTCCTGTGTGCAATAAAACCGCTCTGCTGGAGGGCCTGGAGGTGGATCAGTACATGTGGGGAATCCTGAATGCCATCCA
ACACTCCGAGTTTGAAGAGGTCACCATCGATCCCACGTGCAGCTGGCGGCCGGTGCCCATCAAGTCGGACTTACACATCAAGGACGACCC
TGATGGCATCCCCTCCAAGCGGTTCAAGACCATGAGTCCCAGCCAGATGATCATGCCCAATGTCATGGAGATGATCGCAGCCCTGGGCCC
CGGCCCGTCCCCCTATCCCCTCCCGCCTCCCCCAGGGGGCACCAACTCCAACGACTACAGCAGCCAAGGCAACAACTACCAAGGCCATGG
CAACTTTGACTTCCCCCACGGGAACCCTGGAGGGACATCCATGAATGACTTCATGCACGGGCCCCCCCAGCTCTCCCACCCCCCGGACAT
GCCCAACAACATGGCCGCCCTCGAGAAACCCCTCAGCCACCCCATGCAGGAAACTATGCCACACGCTGGCAGCTCTGACCAGCCCCACCC
CTCCATACAACAAGGTTTGCACGTACCACACCCCAGCAGCCAGTCAGGGCCTCCATTACATCACAGTGGGGCTCCTCCTCCTCCTCCTTC
CCAGCCTCCCCGGCAGCCGCCACAGGCCGCTCCCAGCAGCCATCCACACAGCGACCTGACCTTTAACCCCTCCTCAGCCTTAGAGGGTCA
GGCCGGAGCGCAGGGAGCGTCCGACATGCCGGAGCCTTCGCTGGATCTCCTTCCCGAACTCACAAATCCTGACGAGCTCCTGTCTTATCT
GGACCCCCCCGACCTGCCGAGCAATAGTAACGATGACCTCCTGTCTCTATTTGAGAACAACTGAGGGCCACCCGGTCGGGGCCATCCCTC
CACACTCTGCATCCTACCCCACCTACCCAACACACTTTTCCACCTGGGAGCCTGTGCCCTCAGACCGCCCCGCACCAGAGCCACGGGCTG
TGGGGCGGGGAGCCCTCCCCCGCTGCAGCCCTCTCAGAACAGAGGGGTAGGGAGGGTGCACCAGTGCACCAGGAAGGCTGTGTGGGTCTG
GAGCCCACGTCCCACCTCCACACCCTTGGCTTGGGCCCATGCCCAGCGCAGGCCTGAAGACCACCCTCCCGAGAGGAACCAGCCCGGTAA
GAGGGCACACGCTGATGCGGCTTCCCGGTCCCTCCGCGTGTGCCGATTCCAGATGACCTTCCAGTGTCCCCAAGGTTCTTCCATCTTCTA
GACTGTAACCCTGCCTCCCTGCTTCCTGGTCCAGAGCCTCCCTCCAGTGACTGTGGAGCCTGAGAAGGCCCCCGGGCCCCAGCATGGGCC
CCGAGCCTTGGAGGAGCACTGGCAGTTGGTGGCAGTGAGACCAGCCCACCCACCACCACCCACCACAGAAAAGCACAAACCTCTGGGAAA
GACAACGTCTCTCGGGGGCCAGGGGTCATCGGTTTGACCCCTGACCTATAAGCCAAGATACCCCATAAACACACTCAGAAAGCAGAGAAA
AAGGACAAGAGTCTGTGTTTGAGAGGGGGTCTGCCATTCCTGCTTGGGGACTGGTGGGGAAGAGGGCCAGGACATCTTCTGAGCCAGGAC
GTCCCTGAGGCTCCACCTCCAAGCTCAGACAGGGCCCAGGCTTGGGGAACAGAGAGAGCAGGTGTACACCCAACCAAAGTGATTGTGCCC
TTGGTTGGGGGGCGCGGGCATATAACCTGTCAGAAGCAAACAGGAGCGGCAACTTCTAACTTTGCTCCAAGCCACTCTCTTTTTAAACAG
CAACAATTTAAAGCTATGAAGTCACCTGGAGAAAAGGAACGTTGCTCTTGGACAGCAAGCAAACCATTTCTCTCCGTCTGTTCTGTTTTT
CTCCTAGTCCCTCTCCTGCCACCTCTCCAAGACTTCCGTGGGACACCCACTTCCCTCTGTCCTAGTTCTCTTTGTCCAATCAGATGGCAA
GGGCAGTGCGTGGAAAGGCCGGGGAGGTGCAGAAACCAGAGCCCAGGGCAATGGTGTCTGTCCAGCCCCTCCCTCTGTCCCTGTGCTCCA
AGCTGCCCCCGGCTGCAGCCCAGGCCATGGACATGTGCACCAGTATGTACCTGCAGGCATGGGGGGGAGGGGGGCGTGTTTCTGGGCCTG
CCCCAGACACTGCCCTTGGCTGCCAGCCTACCCTGCCTGCACTCCTCCACCATCACAATCTCACCCAAACTCCTGCTCACTCAAGCAAAA
GCAGCCTCTGGCCTTCCCTCCACCGCTTTGCTCCATCTGGCTTACCACTCTCCAGGGCCTCCTGGGGAGCCTGTCCTGTGTTCACTTTGT
TTCAGGCTGGTCTGTGCCCCGTGAGCCACATGGCCTAGGGTGATGCCAGGTTGTCCCGTCACTGGGGTCCCATCTGTAAATTCTTTGCGC
CCTTCCCGGCTGCTGCCTGGGGCCCTTTCCTGCTCTCCCGTCCGCTGTGGGTGGTCCCCAGCTCTCCTCTGTGGGTTTTACCGGAAAGGT
GGCCCCAGCTGTTGACTTCCAGTCACTGTCCCAGACGGCACAAGGTTTTCTGTAGGAAAGCTGCCATTGCCCCGGCCCCTTTTCTTCCTT
TGTCCCGTTGTCGAGGTTTTTTCAAATAGCGTGTTGTTCAGTATGCAAATCAATTATTTTAAGAATCGCTTTTGTAAATATCTTTGTGAA
TATTTTAGTATCGTCTTTGATAATATTCAACATTTTCATGACCTGGTTATAGCCTTTGCTGGTGTTTTTAAAATACCTGGACTCAATGAC
AAAGACCGAGTCTTCTTTTTTTTTAAACAAAAACAAAAAAAGCAACCAGGGCTATTTGTACAGTTGAAGGGGTGAACAGAATGGGCGGCT
GTGCTGGGAGTTGGAAGACCGGGCAGCCCGCTATTTAGAGCCATCCCTCAGTCAGCTGGCAGGGACAAGCCAACGCCAGGTAGCATGTGG
CCACCCTTGCCCAGTGTCTGTGGCCTGGCAAGTGGCCACGCCCTGTGTCAGACCATCTGGGAATTAAGCTCCAGACAGACTTACAGATGC
CTTCCTTAGGAGTTCTTGCTTCTTGCGTTGATACTTTGCCCCAGAAAGGCCTGGGATTCATTCTGGTTCTTATCAGGGTGTGTCCACACT
CTGCTCACAGGTGGATCCACGGCTTTCCAGTGCGGAGAGTCGAGATGCTCCCTGCAGCCCAGGCCCCGGGCACCTCCTGCAACCATCTCT
GGGCTCAGCACCTGAGGCGGGTTTCCTGGGTCCCCTCTCCAGCAAGCCTCCACCAGCAAGCTCGGCCCAGAGCTTCCCTTCCGGCTGGCT
CTGAACCGTGCGTGGTGCCTACAGCCTGCAGTCTGGAGACAAGCTCTTCCGGAGTGCTCTGGGAGCCAGGCCAGGGTGTGAGGGAGGTGC
AGAGGCATCCGGGGCGGGAGCAAGCCCCAGGTTGTGACAGGTGCAGGTAGACAACGCCCATAAACAGAGATGGTCCTGAACTCTGGAGAG
ATCCTTCCCTGATCCTTTCGGACGACTACTTGGAGCCATAAGTAACCTCAGCAAAAACGAGGCCTCTGCAAGCCACTTTTCCATGCCAAG
CATCCACCCGGCCCACAGGCATGTTTCTGCCGCCACTCCGCAAGATGGACAGGGAGCCAGCAGGCAGGCGGGAAGGGCCAAGTACAGGCA
ATCACCCCCATCTTCTTGGTTTGAAGCTTTATCCATGTATCATGTTCCGTGTAGCCATTTTATTTTTTAAGAAACTGCTAATACTTTCTC
CCTAATGGAAGCCCTGATCCCCCAGAGAGCTACAGGTCTGCTCCCGACGGGCCTCGGGCCTGACCCGTCCACACAGGGCCGTGTCAACAG
CAGCGACTCAAGGGACGTGTGTACATATGTAAATGAGAAATAGAGACGTGTCAACAGATGCATTCATTTCTCTTGGAATGTGTATTGTTT
TTATTTTGCGAAACAAAACAAAACAAAAAAAAAAGCTTGGAACTCCATCACGTGGAAAAACTAGATCCTGTTGGTTATAGCATTTGTGAG
TTCTCCACGTCTGTCTCTCTCGCTCATGTAATATACTCTGACCCTGAGTGGAAAGGGGTTTTTGTTCTGTTTTTATTTTACCTACATGTA
CTATTTAGCTTCAGTGTACTAGTCCTGCCACCTGTGTATTTTTAGGGTGCTATGGAAATAATGAAAAGAAACGGGGATTTCAGAAGAAAA
TTGTAACCAAATTCATACTTTGTATAATTTTTGATATCATGATCACAGGTGATTCACACGTACACACATAAACACACCCACCAGTGCAGC
CTGAAGTAACTCCCACAGAAACCATCATCGTCTTTGTACATCGTATGTACAATGCAATCATTTCATACTTTAAACTGGTCAAAAAACTAA
TTGTGATTTCTAGTCTTGCAAAGCTGTATGTAGTTAGATGATGTGACAACCTCTAATATTTATCTAATAAATATGTATTCAGATGAAACC
TGTATATTAGGTGTTCATGTGGTTATTTTGTATTTAAAGATCAAATTATTTGACTATTGCTAGACATTTCTATACTCTGTTGTAACACTG

>5016_5016_5_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000537102_ZMIZ1_chr10_81036937_ENST00000334512_length(amino acids)=973AA_BP=1
MLSSWCEELGRLLLLRHQKSRQSDPPGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQSQVLGN
PMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPA
DFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPP
MGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQP
SSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDI
KPNMSALPPPPANHNDELRLTFPVRDGVVLEPFRLEHNLAVSNHVFHLRPTVHQTLMWRSDLELQFKCYHHEDRQMNTNWPASVQVSVNA
TPLTIERGDNKTSHKPLHLKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSVAASSGNTT
LNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQCFDLESYLQLNCERGTWRCPVCNKTALLEGLEVDQYMWGILNAIQHSEFEEV
TIDPTCSWRPVPIKSDLHIKDDPDGIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHG
NPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPP

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Fusion Gene PPI Analysis for ANXA11-ZMIZ1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ANXA11-ZMIZ1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ANXA11-ZMIZ1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneANXA11C4693381AMYOTROPHIC LATERAL SCLEROSIS 232GENOMICS_ENGLAND;UNIPROT
HgeneANXA11C0002736Amyotrophic Lateral Sclerosis1ORPHANET
HgeneANXA11C0036202Sarcoidosis1CTD_human
TgeneC0025958Microcephaly2GENOMICS_ENGLAND
TgeneC0232466Feeding difficulties2GENOMICS_ENGLAND
TgeneC0243050Cardiovascular Abnormalities2GENOMICS_ENGLAND
TgeneC0262361Growth abnormality2GENOMICS_ENGLAND
TgeneC0557874Global developmental delay2GENOMICS_ENGLAND
TgeneC3714756Intellectual Disability2GENOMICS_ENGLAND
TgeneC4021790Abnormality of the skeletal system2GENOMICS_ENGLAND
TgeneC4021817Abnormality of head or neck2GENOMICS_ENGLAND
TgeneC4021821Abnormality of the urinary system2GENOMICS_ENGLAND
TgeneC0007570Celiac Disease1CTD_human
TgeneC0009402Colorectal Carcinoma1CTD_human
TgeneC0009404Colorectal Neoplasms1CTD_human
TgeneC0036572Seizures1GENOMICS_ENGLAND