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Fusion Gene Summary | |
Fusion Gene ORF analysis | |
Fusion Genomic Features | |
Fusion Protein Features | |
Fusion Gene Sequence | |
Fusion Gene PPI analysis | |
Related Drugs | |
Related Diseases |
Fusion gene:ANXA11-ZMIZ1 (FusionGDB2 ID:HG311TG57178) |
Fusion Gene Summary for ANXA11-ZMIZ1 |
Fusion gene summary |
Fusion gene information | Fusion gene name: ANXA11-ZMIZ1 | Fusion gene ID: hg311tg57178 | Hgene | Tgene | Gene symbol | ANXA11 | ZMIZ1 | Gene ID | 311 | 57178 |
Gene name | annexin A11 | zinc finger MIZ-type containing 1 | |
Synonyms | ALS23|ANX11|CAP-50|CAP50 | MIZ|NEDDFSA|RAI17|TRAFIP10|ZIMP10 | |
Cytomap | ('ANXA11')('ZMIZ1') 10q22.3 | 10q22.3 | |
Type of gene | protein-coding | protein-coding | |
Description | annexin A1156 kDa autoantigenannexin XIannexin-11calcyclin-associated annexin 50epididymis secretory sperm binding protein | zinc finger MIZ domain-containing protein 1retinoic acid induced 17zinc finger-containing, Miz1, PIAS-like protein on chromosome 10 | |
Modification date | 20200313 | 20200315 | |
UniProtAcc | . | . | |
Ensembl transtripts involved in fusion gene | ENST00000265447, ENST00000360615, ENST00000372231, ENST00000422982, ENST00000438331, ENST00000535999, ENST00000537102, ENST00000463657, | ||
Fusion gene scores | * DoF score | 11 X 8 X 4=352 | 7 X 8 X 5=280 |
# samples | 11 | 8 | |
** MAII score | log2(11/352*10)=-1.67807190511264 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/280*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: ANXA11 [Title/Abstract] AND ZMIZ1 [Title/Abstract] AND fusion [Title/Abstract] | ||
Most frequent breakpoint | ANXA11(81917396)-ZMIZ1(81036937), # samples:1 | ||
Anticipated loss of major functional domain due to fusion event. | ANXA11-ZMIZ1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ANXA11-ZMIZ1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ANXA11-ZMIZ1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ANXA11-ZMIZ1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ANXA11-ZMIZ1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Partner | Gene | GO ID | GO term | PubMed ID |
Hgene | ANXA11 | GO:0051592 | response to calcium ion | 9188810|12601007 |
Tgene | ZMIZ1 | GO:0007179 | transforming growth factor beta receptor signaling pathway | 16777850 |
Tgene | ZMIZ1 | GO:0030521 | androgen receptor signaling pathway | 14609956 |
Tgene | ZMIZ1 | GO:0033233 | regulation of protein sumoylation | 14609956 |
Tgene | ZMIZ1 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 26522984 |
Tgene | ZMIZ1 | GO:0060395 | SMAD protein signal transduction | 16777850 |
Tgene | ZMIZ1 | GO:1903508 | positive regulation of nucleic acid-templated transcription | 14609956|16777850 |
Fusion gene breakpoints across ANXA11 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene breakpoints across ZMIZ1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChimerDB4 | KIRC | TCGA-BP-4770 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
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Fusion Gene ORF analysis for ANXA11-ZMIZ1 |
Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
5CDS-intron | ENST00000265447 | ENST00000446377 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
5CDS-intron | ENST00000360615 | ENST00000446377 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
5CDS-intron | ENST00000372231 | ENST00000446377 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
5CDS-intron | ENST00000422982 | ENST00000446377 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
5CDS-intron | ENST00000438331 | ENST00000446377 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
5CDS-intron | ENST00000535999 | ENST00000446377 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
5CDS-intron | ENST00000537102 | ENST00000446377 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
Frame-shift | ENST00000265447 | ENST00000334512 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
Frame-shift | ENST00000360615 | ENST00000334512 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
Frame-shift | ENST00000372231 | ENST00000334512 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
Frame-shift | ENST00000372231 | ENST00000478357 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
Frame-shift | ENST00000422982 | ENST00000334512 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
Frame-shift | ENST00000438331 | ENST00000478357 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
Frame-shift | ENST00000535999 | ENST00000334512 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
Frame-shift | ENST00000535999 | ENST00000478357 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
Frame-shift | ENST00000537102 | ENST00000478357 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
In-frame | ENST00000265447 | ENST00000478357 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
In-frame | ENST00000360615 | ENST00000478357 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
In-frame | ENST00000422982 | ENST00000478357 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
In-frame | ENST00000438331 | ENST00000334512 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
In-frame | ENST00000537102 | ENST00000334512 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
intron-3CDS | ENST00000463657 | ENST00000334512 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
intron-3CDS | ENST00000463657 | ENST00000478357 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
intron-intron | ENST00000463657 | ENST00000446377 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + |
ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
ENST00000438331 | ANXA11 | chr10 | 81917396 | - | ENST00000334512 | ZMIZ1 | chr10 | 81036937 | + | 8635 | 1941 | 1943 | 4864 | 973 |
ENST00000360615 | ANXA11 | chr10 | 81917396 | - | ENST00000478357 | ZMIZ1 | chr10 | 81036937 | + | 6192 | 1940 | 446 | 2089 | 547 |
ENST00000265447 | ANXA11 | chr10 | 81917396 | - | ENST00000478357 | ZMIZ1 | chr10 | 81036937 | + | 5997 | 1745 | 53 | 1894 | 613 |
ENST00000422982 | ANXA11 | chr10 | 81917396 | - | ENST00000478357 | ZMIZ1 | chr10 | 81036937 | + | 5997 | 1745 | 287 | 1894 | 535 |
ENST00000537102 | ANXA11 | chr10 | 81917396 | - | ENST00000334512 | ZMIZ1 | chr10 | 81036937 | + | 8694 | 2000 | 2002 | 4923 | 973 |
DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
ENST00000438331 | ENST00000334512 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + | 0.008600174 | 0.9913999 |
ENST00000360615 | ENST00000478357 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + | 0.012110164 | 0.9878898 |
ENST00000265447 | ENST00000478357 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + | 0.012510043 | 0.98749 |
ENST00000422982 | ENST00000478357 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + | 0.011784754 | 0.9882152 |
ENST00000537102 | ENST00000334512 | ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036937 | + | 0.009898606 | 0.99010134 |
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Fusion Genomic Features for ANXA11-ZMIZ1 |
FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036935 | + | 0.001115402 | 0.9988846 |
ANXA11 | chr10 | 81917396 | - | ZMIZ1 | chr10 | 81036935 | + | 0.001115402 | 0.9988846 |
Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for ANXA11-ZMIZ1 |
Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:81917396/chr10:81036937) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
Main function of each fusion partner protein. (from UniProt) |
Hgene | Tgene |
. | . |
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000265447 | - | 14 | 15 | 200_271 | 486 | 506.0 | Repeat | Annexin 1 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000265447 | - | 14 | 15 | 272_343 | 486 | 506.0 | Repeat | Annexin 2 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000265447 | - | 14 | 15 | 355_427 | 486 | 506.0 | Repeat | Annexin 3 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000360615 | - | 15 | 16 | 200_271 | 486 | 506.0 | Repeat | Annexin 1 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000360615 | - | 15 | 16 | 272_343 | 486 | 506.0 | Repeat | Annexin 2 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000360615 | - | 15 | 16 | 355_427 | 486 | 506.0 | Repeat | Annexin 3 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000372231 | - | 14 | 15 | 200_271 | 486 | 506.0 | Repeat | Annexin 1 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000372231 | - | 14 | 15 | 272_343 | 486 | 506.0 | Repeat | Annexin 2 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000372231 | - | 14 | 15 | 355_427 | 486 | 506.0 | Repeat | Annexin 3 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000422982 | - | 15 | 16 | 200_271 | 486 | 506.0 | Repeat | Annexin 1 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000422982 | - | 15 | 16 | 272_343 | 486 | 506.0 | Repeat | Annexin 2 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000422982 | - | 15 | 16 | 355_427 | 486 | 506.0 | Repeat | Annexin 3 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000438331 | - | 16 | 17 | 200_271 | 486 | 506.0 | Repeat | Annexin 1 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000438331 | - | 16 | 17 | 272_343 | 486 | 506.0 | Repeat | Annexin 2 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000438331 | - | 16 | 17 | 355_427 | 486 | 506.0 | Repeat | Annexin 3 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000535999 | - | 16 | 17 | 200_271 | 486 | 506.0 | Repeat | Annexin 1 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000535999 | - | 16 | 17 | 272_343 | 486 | 506.0 | Repeat | Annexin 2 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000535999 | - | 16 | 17 | 355_427 | 486 | 506.0 | Repeat | Annexin 3 |
Tgene | ZMIZ1 | chr10:81917396 | chr10:81036937 | ENST00000334512 | 6 | 25 | 280_305 | 93 | 1068.0 | Compositional bias | Note=Ala-rich | |
Tgene | ZMIZ1 | chr10:81917396 | chr10:81036937 | ENST00000334512 | 6 | 25 | 334_555 | 93 | 1068.0 | Compositional bias | Note=Pro-rich | |
Tgene | ZMIZ1 | chr10:81917396 | chr10:81036937 | ENST00000334512 | 6 | 25 | 867_1002 | 93 | 1068.0 | Compositional bias | Note=Pro-rich | |
Tgene | ZMIZ1 | chr10:81917396 | chr10:81036937 | ENST00000334512 | 6 | 25 | 837_1067 | 93 | 1068.0 | Region | Transactivation domain | |
Tgene | ZMIZ1 | chr10:81917396 | chr10:81036937 | ENST00000334512 | 6 | 25 | 727_804 | 93 | 1068.0 | Zinc finger | SP-RING-type |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000265447 | - | 14 | 15 | 431_502 | 486 | 506.0 | Repeat | Annexin 4 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000360615 | - | 15 | 16 | 431_502 | 486 | 506.0 | Repeat | Annexin 4 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000372231 | - | 14 | 15 | 431_502 | 486 | 506.0 | Repeat | Annexin 4 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000422982 | - | 15 | 16 | 431_502 | 486 | 506.0 | Repeat | Annexin 4 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000438331 | - | 16 | 17 | 431_502 | 486 | 506.0 | Repeat | Annexin 4 |
Hgene | ANXA11 | chr10:81917396 | chr10:81036937 | ENST00000535999 | - | 16 | 17 | 431_502 | 486 | 506.0 | Repeat | Annexin 4 |
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Fusion Gene Sequence for ANXA11-ZMIZ1 |
For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
>5016_5016_1_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000265447_ZMIZ1_chr10_81036937_ENST00000478357_length(transcript)=5997nt_BP=1745nt GCACTGCCTCTGGCACCTGGGGCAGCCGCGCCCGCGGAGTTTTCCGCCCGGCGCTGACGGCTGCTGCGCCCGCGGCTCCCCAGTGCCCCG AGTGCCCCGCGGGCCCCGCGAGCGGGAGTGGGACCCAGCCCCTAGGCAGAACCCAGGCGCCGCGCCCGGGACGCCCGCGGAGAGAGCCAC TCCCGCCCACGTCCCATTTCGCCCCTCGCGTCCGGAGTCCCCGTGGCCAGGTGAGGGCTCTCAGGCAGAGCCTGAATGTGCTTTCGTCTT CTCTTCCAGATCTAACCATGAGCTACCCTGGCTATCCCCCGCCCCCAGGTGGCTACCCACCAGCTGCACCAGGTGGTGGTCCCTGGGGAG GTGCTGCCTACCCTCCTCCGCCCAGCATGCCCCCCATCGGGCTGGATAACGTGGCCACCTATGCGGGGCAGTTCAACCAGGACTATCTCT CGGGAATGGCGGCCAACATGTCTGGGACATTTGGAGGAGCCAACATGCCCAACCTGTACCCTGGGGCCCCTGGGGCTGGCTACCCACCAG TGCCCCCTGGCGGCTTTGGGCAGCCCCCCTCTGCCCAGCAGCCTGTTCCTCCCTATGGGATGTATCCACCCCCAGGAGGAAACCCACCCT CCAGGATGCCCTCATATCCGCCATACCCAGGGGCCCCTGTGCCGGGCCAGCCCATGCCACCCCCCGGACAGCAGCCCCCAGGGGCCTACC CTGGGCAGCCACCAGTGACCTACCCTGGTCAGCCTCCAGTGCCACTCCCTGGGCAGCAGCAGCCAGTGCCGAGCTACCCAGGATACCCGG GGTCTGGGACTGTCACCCCCGCTGTGCCCCCAACCCAGTTTGGAAGCCGAGGCACCATCACTGATGCTCCCGGCTTTGACCCCCTGCGAG ATGCCGAGGTCCTGCGGAAGGCCATGAAAGGCTTCGGGACGGATGAGCAGGCCATCATTGACTGCCTGGGGAGTCGCTCCAACAAGCAGC GGCAGCAGATCCTACTTTCCTTCAAGACGGCTTACGGCAAGGATTTGATCAAAGATCTGAAATCTGAACTGTCAGGAAACTTTGAGAAGA CAATCTTGGCTCTGATGAAGACCCCAGTCCTCTTTGACATTTATGAGATAAAGGAAGCCATCAAGGGGGTTGGCACTGATGAAGCCTGCC TGATTGAGATCCTCGCTTCCCGCAGCAATGAGCACATCCGAGAATTAAACAGAGCCTACAAAGCAGAATTCAAAAAGACCCTGGAAGAGG CCATTCGAAGCGACACATCAGGGCACTTCCAGCGGCTCCTCATCTCTCTCTCTCAGGGAAACCGTGATGAAAGCACAAACGTGGACATGT CACTCGCCCAGAGAGATGCCCAGGAGCTGTATGCGGCCGGGGAGAACCGCCTGGGAACAGACGAGTCCAAGTTCAATGCGGTTCTGTGCT CCCGGAGCCGGGCCCACCTGGTAGCAGTTTTCAATGAGTACCAGAGAATGACAGGCCGGGACATTGAGAAGAGCATCTGCCGGGAGATGT CCGGGGACCTGGAGGAGGGCATGCTGGCCGTGGTGAAATGTCTCAAGAATACCCCAGCCTTCTTTGCGGAGAGGCTCAACAAGGCCATGA GGGGGGCAGGAACAAAGGACCGGACCCTGATTCGCATCATGGTGTCTCGCAGCGAGACCGACCTCCTGGACATCAGATCAGAGTATAAGC GGATGTACGGCAAGTCGCTGTACCACGACATCTCGAGCCTTGTTGTCCTCCTGGTGCGAAGAGCTCGGCCGCCTGCTGCTGCTCCGACAT CAGAAGAGCCGCCAGAGCGATCCCCCTGGGAAACTCCCCATGCAGCCCCCTCTCAGCTCCATGAGCTCCATGAAACCCACTCTGTCGCAC AGTGATGGGTCGTTCCCCTATGACTCTGTCCCTTGGCAGCAGAACACCAACCAGCCTCCCGGCTCCCTTTCCGTGGTCACCACGGTTTGG GGAGTAACCAACACATCCCAGAGCCAGGTCCTTGGGAACCCTATGGCCAATGCCAACAACCCCATGAATCCAGGCGGCAACCCCATGGCG TCGGGCATGACCACCAGCAACCCAGGCCTCAACTCCCCACAGTTTGCGGGGCAGCAGCAGCAGTTCTCAGCCAAGGCTGGCCCCGCTCAG CCCTACATCCAGCAGAGCATGTATGGCCGGCCCAACTACCCCGGCAGCGGGGGCTTTGGGGCCAGTTACCCTGGGGGTCCTAACGCCCCC GCAGGCATGGGCATCCCTCCGCACACCAGGCCGCCTGCTGACTTCACTCAGCCCGCGGCAGCCGCTGCAGCAGCGGCAGTGGCAGCAGCA GCAGCCACAGCTACAGCCACAGCCACGGCCACTGTGGCAGCCCTGCAGGAGACACAGAACAAGGATATAAACCAGTATGGACCGGTCTGT TCCTCTTTCCAGATGGGTCCCACCCAGGCGTATAACAGCCAATTCATGAACCAGCCCGGGCCGCGGGGGCCTGCCTCCATGGGGGGCAGC ATGAACCCCGCGAGCATGGCGGCTGGCATGACGCCCTCGGGGATGAGCGGCCCTCCCATGGGCATGAACCAGCCCCGGCCGCCCGGCATC AGCCCCTTTGGCACACACGGGCAGCGGATGCCCCAGCAGACCTACCCGGGCCCCCGGCCCCAGTCCCTTCCTATTCAGAACATAAAGAGG CCATACCCTGGAGAGGTGAGTGCAGCAGTGGGAGCCTGGGAGGTGGGAACTGGGACACCTGGGCTTGAAGACATGGGCCGTGGGTACGGC TTTGGAAGGGGTGTGGCTTGGACTCCAGCACACTTGGACAAAGAGGCAGGGGCTTAGGGGTCAGGTGCTCCTGGGTTTGAGACCTGGTTC TGCTGTTTCCCAACTGAAAGACCTCGAGCCAGTCACCCTGCCTCCTAGGGCTGCTTGAGGGACTTGAGGAGGTGTCCGTGAAGTGCTTGG CCCTGGGCTGGCATGTGCCGCCACTCAGCAAGCAGCAGTTCCTCTTACTGTAGTGACTCTTGTCTTGGCTCAGCCACTAACTGGGTGACC TGGGTTTAGTTCCTCCTGCCCACATGAGAGCTTCCCCAACTCCTCTCCAAGAAAGAGAGCTGAGACAAAATGCTTCCAGTCTATAAGGGC TGACCCGTCCGGGAAGTGACTGGAAGGCAGGCAGCGTGTTTCCAGTCTGTAAGGATTGACCTGTTGGGGAAGTGACTGGAAGGCAGAGAG CGTGTTTCCAATCTATAAGGACTGACCCGTTGGGGAAGTGACTGGAAGGCCGGCAGCTGTTTCCAGTCTATAAGGACTGACCCGTCAGGG AAGTGACTGGAAGGCAGACAGCGTGTTTCTTAGCTCTTGTTTCCATCCACACTTGGTCACTGTATAGGAAGTGGCACTGCCTCTTGGGCT GCACAGCCAGCTCAGCCAAGGTGTTGGGGAAGATTTGGGGAAGTAAAACCCACACCTCCTGCCCTCTGGGAAGTGAGGTTTTAGCAGGAA AGAAAAGTTTTTAGCAGAGACTCACCAGGGAATGAAGCATAGCAGACTGCACAGAACTCAATATGAGTCAGAGAAGGCAGGCTTCCTGGA GGGTGTGTCACAAGTAAATCCTCAGAAAATGATGCTGGCAGCAGCTGGCCCATCTGGGTACCCAGGTAAGGATTTAGTTTACCTGCAGAA GACGTAGGGACGTGGCTCTGCAGATGCCCCTCGTGAAGCCCTGGTTGCTCCCCACGACCAAGCCCCTTTTTGAGCAGGGTGTGCCCAGCT CTCTGCCTGCCTCCCTCCCAGCTTGCATGCCCACTCTCAGAGCAGTTTTCTCCTCCTAGCTCCTCTCAGCTCTGTGGCCTTCACCTTGGG TTCACAGCGGCTTTAGATTCCAAAGACCTTAAGTTCCTTGAAGATCTGCACATTTCCCCTCAGTATCCACCTTAGGATGGGCGGGGAGGC TTGGCAACAAGTGGAGGTATTCTGAGTTCAGGAGGGGAGAGAGAGGGGGGGGGGTCAGGGGCTTCCTCATGCATCCAAGAAGCTGGATCA AGCCCCAACCCTCCACCTGGTGGACACTAGTTCAGGGAGGGGCCAGAGAAGGACCATTGGCTCCTGGGTCCTGAGTTTGGGGGAGCCTCA AGCTATTGGCACCTCTCCTGGCACTCAGGCCCCATGCAGTTTCTAGGCCTTTTCTCAGCCACCCTGTGCTCAAAATCCCAGTGTCCCACT GGCTGTGCTGGGGGTGCATCTGTTAGCCCACGCCAAAGGAGGCAATCTCGGATGAGGCTTCAGCAGAATTCCTGGTCATTGGTGTCACCC CTGCACCTGCACCTGTGCCATGCTTATGGCTCTTGCCTGCCTAAAGAGAGCACACCAAAGGCTCTCCATATTTTTACTAAATTAATCATC CTTTTCATAGAGTGCTGCTGCTACCCAGCTACAGCACTGGGTGGTCACAGCCTATGCGGCCTGATCCTGTCTGGAAGACTGGCCTTCCTT CCCCTTGCCATGGCTTGTTCATACAATATTTGAATTGTTGGAGCCTTAGGACAGGGGTTGGGTCATCTGGTCCCACAGAGGACTCTCTTC TCTAGCTTGGTGGGCAGGTAGGCACCAGCTACGTCTTCTATACCTCCTGTGGTGGGTGCCTCACTGTCACCCAGAGCAGCCACCATGTTG CAACAACGTGAGTTGTAGATTCTTCCACACTGACACTTTCTGACATTTATCCCTAAGTCCATCATTCGTTTGTTGAGCAAGTATTAAGGG TATTTTCCCAGGCACTGGGGCACAGCCACCAACAGGACCTCTGGGCAAGAGAGACACTCAGATGGGGAAGAAGAAACCACTGACTCACAG GATGTCATGTGGCCGTGAGGGTCACCTGATTTTCCAGACAGGGAAGGTGGCTGGAGGGTGGTGCTCTCTCCTCTTCTCTAAATTGTCTGT CCCGGGAGAAGTTGTCTTGTTCCTTCACCAACCTGGCTCTCCCACCTCCTGCACAGGTGGCAGGTTGTCGATGGCCCAGAACTGAACACT AGGTGTGTGTTCTGCTCTGAGGGGAGTACGAGGACAATGCCACCCAAGTTCAGCCTTGGAATGCAGGGGCACAGGGGGCTCCTTTCTGGA ATTGCATCCTGTTGACTGTGTTCCTCTGTCACATTGGGGTACACATTGGGGAGCACAGCCCTAACCCAGGCACCAGGAGAGACACAAAGG TCGGGGGAGTTAGAATCAGGCCCCTCATAATGGTGTGAGCAAGAGGCTCTGAAAGTGTCCCTGGAGTTCAGGGGCACATGTGCTCCAGGA AGAACGGCCTCAAGGGGAGGTGGCCTATGATCTGGACAGGCAGAACAAAATGCCCCTGGATGTCAGGACGAGAAGGGGCCCAAAGCATTA TCTGGTTTTGTGGGTGGGAAACAGCAGGAGCAAATGAGGAGAGGCGGGCCCCATCCCGTTGTTCAGGTGACCTGGCTATGTGACGTTGGC AACATTGAACGTGTTTCCCCTCTCCTTTCTCTCCCACCACAGCCCAACTATGGAAACCAGCAATATGGACCAAACAGCCAGTTCCCCACC CAGCCAGGCCAGTACCCAGCCCCCAACCCCCCGAGGCCACTCACCTCCCCCAACTACCCAGGACAGAGGATGCCCAGCCAGCCGAGCTCC GGGCAGTACCCGCCCCCCACGGTCAACATGGGGCAGTATTACAAGGTGAGTCCCAGCCTCGCCACCACCCACGGGGCCCCTTCCCTCCTA ACCACCTCACTCCCCTAACTCCACCGGGATCACTCTGACCCTGCGTGTGTTTGCCCCAAGGACAGCGAGGGGTGGGTGATTTCTGAACGT CCCCATGTGTTCAGGGCGAAGTTCGGTGGCCAGAATGTCAGAGTGGCTTTTCTCAGTTCCTATTCTCATTCGTCTCGGATGATGGTTTTT >5016_5016_1_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000265447_ZMIZ1_chr10_81036937_ENST00000478357_length(amino acids)=613AA_BP=564 MTAAAPAAPQCPECPAGPASGSGTQPLGRTQAPRPGRPRREPLPPTSHFAPRVRSPRGQVRALRQSLNVLSSSLPDLTMSYPGYPPPPGG YPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPP YGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVTPAVPPTQFGSRG TITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIK EAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRL GTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRS -------------------------------------------------------------- >5016_5016_2_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000360615_ZMIZ1_chr10_81036937_ENST00000478357_length(transcript)=6192nt_BP=1940nt GCACTGCCTCTGGCACCTGGGGCAGCCGCGCCCGCGGAGTTTTCCGCCCGGCGCTGACGGCTGCTGCGCCCGCGGCTCCCCAGTGCCCCG AGTGCCCCGCGGGCCCCGCGAGCGGGAGTGGGACCCAGCCCCTAGGCAGAACCCAGGCGCCGCGCCCGGGACGCCCGCGGAGAGAGCCAC TCCCGCCCACGTCCCATTTCGCCCCTCGCGTCCGGAGTCCCCGTGGCCAGGGATTATTGGACCTGCCTGGTTTAAACTATTGTCTTAGTT AATTTTGTGCTGCTCTAACAAAATATCACAGACTGAGTAATTTATAAGCAATAGTAGCTTATTTGGCTCACAGTTCTGGAGGCTGAGAAG ATCGTGAGGCTGCATCTGGCAAGGGCCTTCTTGCTGCTTCATAACATGGCAGAAGACATCATGCGGCAGGGGCTCTCAGGCAGAGCCTGA ATGTGCTTTCGTCTTCTCTTCCAGATCTAACCATGAGCTACCCTGGCTATCCCCCGCCCCCAGGTGGCTACCCACCAGCTGCACCAGGTG GTGGTCCCTGGGGAGGTGCTGCCTACCCTCCTCCGCCCAGCATGCCCCCCATCGGGCTGGATAACGTGGCCACCTATGCGGGGCAGTTCA ACCAGGACTATCTCTCGGGAATGGCGGCCAACATGTCTGGGACATTTGGAGGAGCCAACATGCCCAACCTGTACCCTGGGGCCCCTGGGG CTGGCTACCCACCAGTGCCCCCTGGCGGCTTTGGGCAGCCCCCCTCTGCCCAGCAGCCTGTTCCTCCCTATGGGATGTATCCACCCCCAG GAGGAAACCCACCCTCCAGGATGCCCTCATATCCGCCATACCCAGGGGCCCCTGTGCCGGGCCAGCCCATGCCACCCCCCGGACAGCAGC CCCCAGGGGCCTACCCTGGGCAGCCACCAGTGACCTACCCTGGTCAGCCTCCAGTGCCACTCCCTGGGCAGCAGCAGCCAGTGCCGAGCT ACCCAGGATACCCGGGGTCTGGGACTGTCACCCCCGCTGTGCCCCCAACCCAGTTTGGAAGCCGAGGCACCATCACTGATGCTCCCGGCT TTGACCCCCTGCGAGATGCCGAGGTCCTGCGGAAGGCCATGAAAGGCTTCGGGACGGATGAGCAGGCCATCATTGACTGCCTGGGGAGTC GCTCCAACAAGCAGCGGCAGCAGATCCTACTTTCCTTCAAGACGGCTTACGGCAAGGATTTGATCAAAGATCTGAAATCTGAACTGTCAG GAAACTTTGAGAAGACAATCTTGGCTCTGATGAAGACCCCAGTCCTCTTTGACATTTATGAGATAAAGGAAGCCATCAAGGGGGTTGGCA CTGATGAAGCCTGCCTGATTGAGATCCTCGCTTCCCGCAGCAATGAGCACATCCGAGAATTAAACAGAGCCTACAAAGCAGAATTCAAAA AGACCCTGGAAGAGGCCATTCGAAGCGACACATCAGGGCACTTCCAGCGGCTCCTCATCTCTCTCTCTCAGGGAAACCGTGATGAAAGCA CAAACGTGGACATGTCACTCGCCCAGAGAGATGCCCAGGAGCTGTATGCGGCCGGGGAGAACCGCCTGGGAACAGACGAGTCCAAGTTCA ATGCGGTTCTGTGCTCCCGGAGCCGGGCCCACCTGGTAGCAGTTTTCAATGAGTACCAGAGAATGACAGGCCGGGACATTGAGAAGAGCA TCTGCCGGGAGATGTCCGGGGACCTGGAGGAGGGCATGCTGGCCGTGGTGAAATGTCTCAAGAATACCCCAGCCTTCTTTGCGGAGAGGC TCAACAAGGCCATGAGGGGGGCAGGAACAAAGGACCGGACCCTGATTCGCATCATGGTGTCTCGCAGCGAGACCGACCTCCTGGACATCA GATCAGAGTATAAGCGGATGTACGGCAAGTCGCTGTACCACGACATCTCGAGCCTTGTTGTCCTCCTGGTGCGAAGAGCTCGGCCGCCTG CTGCTGCTCCGACATCAGAAGAGCCGCCAGAGCGATCCCCCTGGGAAACTCCCCATGCAGCCCCCTCTCAGCTCCATGAGCTCCATGAAA CCCACTCTGTCGCACAGTGATGGGTCGTTCCCCTATGACTCTGTCCCTTGGCAGCAGAACACCAACCAGCCTCCCGGCTCCCTTTCCGTG GTCACCACGGTTTGGGGAGTAACCAACACATCCCAGAGCCAGGTCCTTGGGAACCCTATGGCCAATGCCAACAACCCCATGAATCCAGGC GGCAACCCCATGGCGTCGGGCATGACCACCAGCAACCCAGGCCTCAACTCCCCACAGTTTGCGGGGCAGCAGCAGCAGTTCTCAGCCAAG GCTGGCCCCGCTCAGCCCTACATCCAGCAGAGCATGTATGGCCGGCCCAACTACCCCGGCAGCGGGGGCTTTGGGGCCAGTTACCCTGGG GGTCCTAACGCCCCCGCAGGCATGGGCATCCCTCCGCACACCAGGCCGCCTGCTGACTTCACTCAGCCCGCGGCAGCCGCTGCAGCAGCG GCAGTGGCAGCAGCAGCAGCCACAGCTACAGCCACAGCCACGGCCACTGTGGCAGCCCTGCAGGAGACACAGAACAAGGATATAAACCAG TATGGACCGGTCTGTTCCTCTTTCCAGATGGGTCCCACCCAGGCGTATAACAGCCAATTCATGAACCAGCCCGGGCCGCGGGGGCCTGCC TCCATGGGGGGCAGCATGAACCCCGCGAGCATGGCGGCTGGCATGACGCCCTCGGGGATGAGCGGCCCTCCCATGGGCATGAACCAGCCC CGGCCGCCCGGCATCAGCCCCTTTGGCACACACGGGCAGCGGATGCCCCAGCAGACCTACCCGGGCCCCCGGCCCCAGTCCCTTCCTATT CAGAACATAAAGAGGCCATACCCTGGAGAGGTGAGTGCAGCAGTGGGAGCCTGGGAGGTGGGAACTGGGACACCTGGGCTTGAAGACATG GGCCGTGGGTACGGCTTTGGAAGGGGTGTGGCTTGGACTCCAGCACACTTGGACAAAGAGGCAGGGGCTTAGGGGTCAGGTGCTCCTGGG TTTGAGACCTGGTTCTGCTGTTTCCCAACTGAAAGACCTCGAGCCAGTCACCCTGCCTCCTAGGGCTGCTTGAGGGACTTGAGGAGGTGT CCGTGAAGTGCTTGGCCCTGGGCTGGCATGTGCCGCCACTCAGCAAGCAGCAGTTCCTCTTACTGTAGTGACTCTTGTCTTGGCTCAGCC ACTAACTGGGTGACCTGGGTTTAGTTCCTCCTGCCCACATGAGAGCTTCCCCAACTCCTCTCCAAGAAAGAGAGCTGAGACAAAATGCTT CCAGTCTATAAGGGCTGACCCGTCCGGGAAGTGACTGGAAGGCAGGCAGCGTGTTTCCAGTCTGTAAGGATTGACCTGTTGGGGAAGTGA CTGGAAGGCAGAGAGCGTGTTTCCAATCTATAAGGACTGACCCGTTGGGGAAGTGACTGGAAGGCCGGCAGCTGTTTCCAGTCTATAAGG ACTGACCCGTCAGGGAAGTGACTGGAAGGCAGACAGCGTGTTTCTTAGCTCTTGTTTCCATCCACACTTGGTCACTGTATAGGAAGTGGC ACTGCCTCTTGGGCTGCACAGCCAGCTCAGCCAAGGTGTTGGGGAAGATTTGGGGAAGTAAAACCCACACCTCCTGCCCTCTGGGAAGTG AGGTTTTAGCAGGAAAGAAAAGTTTTTAGCAGAGACTCACCAGGGAATGAAGCATAGCAGACTGCACAGAACTCAATATGAGTCAGAGAA GGCAGGCTTCCTGGAGGGTGTGTCACAAGTAAATCCTCAGAAAATGATGCTGGCAGCAGCTGGCCCATCTGGGTACCCAGGTAAGGATTT AGTTTACCTGCAGAAGACGTAGGGACGTGGCTCTGCAGATGCCCCTCGTGAAGCCCTGGTTGCTCCCCACGACCAAGCCCCTTTTTGAGC AGGGTGTGCCCAGCTCTCTGCCTGCCTCCCTCCCAGCTTGCATGCCCACTCTCAGAGCAGTTTTCTCCTCCTAGCTCCTCTCAGCTCTGT GGCCTTCACCTTGGGTTCACAGCGGCTTTAGATTCCAAAGACCTTAAGTTCCTTGAAGATCTGCACATTTCCCCTCAGTATCCACCTTAG GATGGGCGGGGAGGCTTGGCAACAAGTGGAGGTATTCTGAGTTCAGGAGGGGAGAGAGAGGGGGGGGGGTCAGGGGCTTCCTCATGCATC CAAGAAGCTGGATCAAGCCCCAACCCTCCACCTGGTGGACACTAGTTCAGGGAGGGGCCAGAGAAGGACCATTGGCTCCTGGGTCCTGAG TTTGGGGGAGCCTCAAGCTATTGGCACCTCTCCTGGCACTCAGGCCCCATGCAGTTTCTAGGCCTTTTCTCAGCCACCCTGTGCTCAAAA TCCCAGTGTCCCACTGGCTGTGCTGGGGGTGCATCTGTTAGCCCACGCCAAAGGAGGCAATCTCGGATGAGGCTTCAGCAGAATTCCTGG TCATTGGTGTCACCCCTGCACCTGCACCTGTGCCATGCTTATGGCTCTTGCCTGCCTAAAGAGAGCACACCAAAGGCTCTCCATATTTTT ACTAAATTAATCATCCTTTTCATAGAGTGCTGCTGCTACCCAGCTACAGCACTGGGTGGTCACAGCCTATGCGGCCTGATCCTGTCTGGA AGACTGGCCTTCCTTCCCCTTGCCATGGCTTGTTCATACAATATTTGAATTGTTGGAGCCTTAGGACAGGGGTTGGGTCATCTGGTCCCA CAGAGGACTCTCTTCTCTAGCTTGGTGGGCAGGTAGGCACCAGCTACGTCTTCTATACCTCCTGTGGTGGGTGCCTCACTGTCACCCAGA GCAGCCACCATGTTGCAACAACGTGAGTTGTAGATTCTTCCACACTGACACTTTCTGACATTTATCCCTAAGTCCATCATTCGTTTGTTG AGCAAGTATTAAGGGTATTTTCCCAGGCACTGGGGCACAGCCACCAACAGGACCTCTGGGCAAGAGAGACACTCAGATGGGGAAGAAGAA ACCACTGACTCACAGGATGTCATGTGGCCGTGAGGGTCACCTGATTTTCCAGACAGGGAAGGTGGCTGGAGGGTGGTGCTCTCTCCTCTT CTCTAAATTGTCTGTCCCGGGAGAAGTTGTCTTGTTCCTTCACCAACCTGGCTCTCCCACCTCCTGCACAGGTGGCAGGTTGTCGATGGC CCAGAACTGAACACTAGGTGTGTGTTCTGCTCTGAGGGGAGTACGAGGACAATGCCACCCAAGTTCAGCCTTGGAATGCAGGGGCACAGG GGGCTCCTTTCTGGAATTGCATCCTGTTGACTGTGTTCCTCTGTCACATTGGGGTACACATTGGGGAGCACAGCCCTAACCCAGGCACCA GGAGAGACACAAAGGTCGGGGGAGTTAGAATCAGGCCCCTCATAATGGTGTGAGCAAGAGGCTCTGAAAGTGTCCCTGGAGTTCAGGGGC ACATGTGCTCCAGGAAGAACGGCCTCAAGGGGAGGTGGCCTATGATCTGGACAGGCAGAACAAAATGCCCCTGGATGTCAGGACGAGAAG GGGCCCAAAGCATTATCTGGTTTTGTGGGTGGGAAACAGCAGGAGCAAATGAGGAGAGGCGGGCCCCATCCCGTTGTTCAGGTGACCTGG CTATGTGACGTTGGCAACATTGAACGTGTTTCCCCTCTCCTTTCTCTCCCACCACAGCCCAACTATGGAAACCAGCAATATGGACCAAAC AGCCAGTTCCCCACCCAGCCAGGCCAGTACCCAGCCCCCAACCCCCCGAGGCCACTCACCTCCCCCAACTACCCAGGACAGAGGATGCCC AGCCAGCCGAGCTCCGGGCAGTACCCGCCCCCCACGGTCAACATGGGGCAGTATTACAAGGTGAGTCCCAGCCTCGCCACCACCCACGGG GCCCCTTCCCTCCTAACCACCTCACTCCCCTAACTCCACCGGGATCACTCTGACCCTGCGTGTGTTTGCCCCAAGGACAGCGAGGGGTGG GTGATTTCTGAACGTCCCCATGTGTTCAGGGCGAAGTTCGGTGGCCAGAATGTCAGAGTGGCTTTTCTCAGTTCCTATTCTCATTCGTCT >5016_5016_2_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000360615_ZMIZ1_chr10_81036937_ENST00000478357_length(amino acids)=547AA_BP=498 MNVLSSSLPDLTMSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFGGANMPNLYPGAP GAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVP SYPGYPGSGTVTPAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSEL SGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDE STNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAE RLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISSLVVLLVRRARPPAAAPTSEEPPERSPWETPHAAPSQLHELH -------------------------------------------------------------- >5016_5016_3_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000422982_ZMIZ1_chr10_81036937_ENST00000478357_length(transcript)=5997nt_BP=1745nt GCACTGCCTCTGGCACCTGGGGCAGCCGCGCCCGCGGAGTTTTCCGCCCGGCGCTGACGGCTGCTGCGCCCGCGGCTCCCCAGTGCCCCG AGTGCCCCGCGGGCCCCGCGAGCGGGAGTGGGACCCAGCCCCTAGGCAGAACCCAGGCGCCGCGCCCGGGACGCCCGCGGAGAGAGCCAC TCCCGCCCACGTCCCATTTCGCCCCTCGCGTCCGGAGTCCCCGTGGCCAGGTGTGTGTCTGGGGAAGAGACTTACAGAAGTGGAGTTGCT GAGTCAAAGATCTAACCATGAGCTACCCTGGCTATCCCCCGCCCCCAGGTGGCTACCCACCAGCTGCACCAGGTGGTGGTCCCTGGGGAG GTGCTGCCTACCCTCCTCCGCCCAGCATGCCCCCCATCGGGCTGGATAACGTGGCCACCTATGCGGGGCAGTTCAACCAGGACTATCTCT CGGGAATGGCGGCCAACATGTCTGGGACATTTGGAGGAGCCAACATGCCCAACCTGTACCCTGGGGCCCCTGGGGCTGGCTACCCACCAG TGCCCCCTGGCGGCTTTGGGCAGCCCCCCTCTGCCCAGCAGCCTGTTCCTCCCTATGGGATGTATCCACCCCCAGGAGGAAACCCACCCT CCAGGATGCCCTCATATCCGCCATACCCAGGGGCCCCTGTGCCGGGCCAGCCCATGCCACCCCCCGGACAGCAGCCCCCAGGGGCCTACC CTGGGCAGCCACCAGTGACCTACCCTGGTCAGCCTCCAGTGCCACTCCCTGGGCAGCAGCAGCCAGTGCCGAGCTACCCAGGATACCCGG GGTCTGGGACTGTCACCCCCGCTGTGCCCCCAACCCAGTTTGGAAGCCGAGGCACCATCACTGATGCTCCCGGCTTTGACCCCCTGCGAG ATGCCGAGGTCCTGCGGAAGGCCATGAAAGGCTTCGGGACGGATGAGCAGGCCATCATTGACTGCCTGGGGAGTCGCTCCAACAAGCAGC GGCAGCAGATCCTACTTTCCTTCAAGACGGCTTACGGCAAGGATTTGATCAAAGATCTGAAATCTGAACTGTCAGGAAACTTTGAGAAGA CAATCTTGGCTCTGATGAAGACCCCAGTCCTCTTTGACATTTATGAGATAAAGGAAGCCATCAAGGGGGTTGGCACTGATGAAGCCTGCC TGATTGAGATCCTCGCTTCCCGCAGCAATGAGCACATCCGAGAATTAAACAGAGCCTACAAAGCAGAATTCAAAAAGACCCTGGAAGAGG CCATTCGAAGCGACACATCAGGGCACTTCCAGCGGCTCCTCATCTCTCTCTCTCAGGGAAACCGTGATGAAAGCACAAACGTGGACATGT CACTCGCCCAGAGAGATGCCCAGGAGCTGTATGCGGCCGGGGAGAACCGCCTGGGAACAGACGAGTCCAAGTTCAATGCGGTTCTGTGCT CCCGGAGCCGGGCCCACCTGGTAGCAGTTTTCAATGAGTACCAGAGAATGACAGGCCGGGACATTGAGAAGAGCATCTGCCGGGAGATGT CCGGGGACCTGGAGGAGGGCATGCTGGCCGTGGTGAAATGTCTCAAGAATACCCCAGCCTTCTTTGCGGAGAGGCTCAACAAGGCCATGA GGGGGGCAGGAACAAAGGACCGGACCCTGATTCGCATCATGGTGTCTCGCAGCGAGACCGACCTCCTGGACATCAGATCAGAGTATAAGC GGATGTACGGCAAGTCGCTGTACCACGACATCTCGAGCCTTGTTGTCCTCCTGGTGCGAAGAGCTCGGCCGCCTGCTGCTGCTCCGACAT CAGAAGAGCCGCCAGAGCGATCCCCCTGGGAAACTCCCCATGCAGCCCCCTCTCAGCTCCATGAGCTCCATGAAACCCACTCTGTCGCAC AGTGATGGGTCGTTCCCCTATGACTCTGTCCCTTGGCAGCAGAACACCAACCAGCCTCCCGGCTCCCTTTCCGTGGTCACCACGGTTTGG GGAGTAACCAACACATCCCAGAGCCAGGTCCTTGGGAACCCTATGGCCAATGCCAACAACCCCATGAATCCAGGCGGCAACCCCATGGCG TCGGGCATGACCACCAGCAACCCAGGCCTCAACTCCCCACAGTTTGCGGGGCAGCAGCAGCAGTTCTCAGCCAAGGCTGGCCCCGCTCAG CCCTACATCCAGCAGAGCATGTATGGCCGGCCCAACTACCCCGGCAGCGGGGGCTTTGGGGCCAGTTACCCTGGGGGTCCTAACGCCCCC GCAGGCATGGGCATCCCTCCGCACACCAGGCCGCCTGCTGACTTCACTCAGCCCGCGGCAGCCGCTGCAGCAGCGGCAGTGGCAGCAGCA GCAGCCACAGCTACAGCCACAGCCACGGCCACTGTGGCAGCCCTGCAGGAGACACAGAACAAGGATATAAACCAGTATGGACCGGTCTGT TCCTCTTTCCAGATGGGTCCCACCCAGGCGTATAACAGCCAATTCATGAACCAGCCCGGGCCGCGGGGGCCTGCCTCCATGGGGGGCAGC ATGAACCCCGCGAGCATGGCGGCTGGCATGACGCCCTCGGGGATGAGCGGCCCTCCCATGGGCATGAACCAGCCCCGGCCGCCCGGCATC AGCCCCTTTGGCACACACGGGCAGCGGATGCCCCAGCAGACCTACCCGGGCCCCCGGCCCCAGTCCCTTCCTATTCAGAACATAAAGAGG CCATACCCTGGAGAGGTGAGTGCAGCAGTGGGAGCCTGGGAGGTGGGAACTGGGACACCTGGGCTTGAAGACATGGGCCGTGGGTACGGC TTTGGAAGGGGTGTGGCTTGGACTCCAGCACACTTGGACAAAGAGGCAGGGGCTTAGGGGTCAGGTGCTCCTGGGTTTGAGACCTGGTTC TGCTGTTTCCCAACTGAAAGACCTCGAGCCAGTCACCCTGCCTCCTAGGGCTGCTTGAGGGACTTGAGGAGGTGTCCGTGAAGTGCTTGG CCCTGGGCTGGCATGTGCCGCCACTCAGCAAGCAGCAGTTCCTCTTACTGTAGTGACTCTTGTCTTGGCTCAGCCACTAACTGGGTGACC TGGGTTTAGTTCCTCCTGCCCACATGAGAGCTTCCCCAACTCCTCTCCAAGAAAGAGAGCTGAGACAAAATGCTTCCAGTCTATAAGGGC TGACCCGTCCGGGAAGTGACTGGAAGGCAGGCAGCGTGTTTCCAGTCTGTAAGGATTGACCTGTTGGGGAAGTGACTGGAAGGCAGAGAG CGTGTTTCCAATCTATAAGGACTGACCCGTTGGGGAAGTGACTGGAAGGCCGGCAGCTGTTTCCAGTCTATAAGGACTGACCCGTCAGGG AAGTGACTGGAAGGCAGACAGCGTGTTTCTTAGCTCTTGTTTCCATCCACACTTGGTCACTGTATAGGAAGTGGCACTGCCTCTTGGGCT GCACAGCCAGCTCAGCCAAGGTGTTGGGGAAGATTTGGGGAAGTAAAACCCACACCTCCTGCCCTCTGGGAAGTGAGGTTTTAGCAGGAA AGAAAAGTTTTTAGCAGAGACTCACCAGGGAATGAAGCATAGCAGACTGCACAGAACTCAATATGAGTCAGAGAAGGCAGGCTTCCTGGA GGGTGTGTCACAAGTAAATCCTCAGAAAATGATGCTGGCAGCAGCTGGCCCATCTGGGTACCCAGGTAAGGATTTAGTTTACCTGCAGAA GACGTAGGGACGTGGCTCTGCAGATGCCCCTCGTGAAGCCCTGGTTGCTCCCCACGACCAAGCCCCTTTTTGAGCAGGGTGTGCCCAGCT CTCTGCCTGCCTCCCTCCCAGCTTGCATGCCCACTCTCAGAGCAGTTTTCTCCTCCTAGCTCCTCTCAGCTCTGTGGCCTTCACCTTGGG TTCACAGCGGCTTTAGATTCCAAAGACCTTAAGTTCCTTGAAGATCTGCACATTTCCCCTCAGTATCCACCTTAGGATGGGCGGGGAGGC TTGGCAACAAGTGGAGGTATTCTGAGTTCAGGAGGGGAGAGAGAGGGGGGGGGGTCAGGGGCTTCCTCATGCATCCAAGAAGCTGGATCA AGCCCCAACCCTCCACCTGGTGGACACTAGTTCAGGGAGGGGCCAGAGAAGGACCATTGGCTCCTGGGTCCTGAGTTTGGGGGAGCCTCA AGCTATTGGCACCTCTCCTGGCACTCAGGCCCCATGCAGTTTCTAGGCCTTTTCTCAGCCACCCTGTGCTCAAAATCCCAGTGTCCCACT GGCTGTGCTGGGGGTGCATCTGTTAGCCCACGCCAAAGGAGGCAATCTCGGATGAGGCTTCAGCAGAATTCCTGGTCATTGGTGTCACCC CTGCACCTGCACCTGTGCCATGCTTATGGCTCTTGCCTGCCTAAAGAGAGCACACCAAAGGCTCTCCATATTTTTACTAAATTAATCATC CTTTTCATAGAGTGCTGCTGCTACCCAGCTACAGCACTGGGTGGTCACAGCCTATGCGGCCTGATCCTGTCTGGAAGACTGGCCTTCCTT CCCCTTGCCATGGCTTGTTCATACAATATTTGAATTGTTGGAGCCTTAGGACAGGGGTTGGGTCATCTGGTCCCACAGAGGACTCTCTTC TCTAGCTTGGTGGGCAGGTAGGCACCAGCTACGTCTTCTATACCTCCTGTGGTGGGTGCCTCACTGTCACCCAGAGCAGCCACCATGTTG CAACAACGTGAGTTGTAGATTCTTCCACACTGACACTTTCTGACATTTATCCCTAAGTCCATCATTCGTTTGTTGAGCAAGTATTAAGGG TATTTTCCCAGGCACTGGGGCACAGCCACCAACAGGACCTCTGGGCAAGAGAGACACTCAGATGGGGAAGAAGAAACCACTGACTCACAG GATGTCATGTGGCCGTGAGGGTCACCTGATTTTCCAGACAGGGAAGGTGGCTGGAGGGTGGTGCTCTCTCCTCTTCTCTAAATTGTCTGT CCCGGGAGAAGTTGTCTTGTTCCTTCACCAACCTGGCTCTCCCACCTCCTGCACAGGTGGCAGGTTGTCGATGGCCCAGAACTGAACACT AGGTGTGTGTTCTGCTCTGAGGGGAGTACGAGGACAATGCCACCCAAGTTCAGCCTTGGAATGCAGGGGCACAGGGGGCTCCTTTCTGGA ATTGCATCCTGTTGACTGTGTTCCTCTGTCACATTGGGGTACACATTGGGGAGCACAGCCCTAACCCAGGCACCAGGAGAGACACAAAGG TCGGGGGAGTTAGAATCAGGCCCCTCATAATGGTGTGAGCAAGAGGCTCTGAAAGTGTCCCTGGAGTTCAGGGGCACATGTGCTCCAGGA AGAACGGCCTCAAGGGGAGGTGGCCTATGATCTGGACAGGCAGAACAAAATGCCCCTGGATGTCAGGACGAGAAGGGGCCCAAAGCATTA TCTGGTTTTGTGGGTGGGAAACAGCAGGAGCAAATGAGGAGAGGCGGGCCCCATCCCGTTGTTCAGGTGACCTGGCTATGTGACGTTGGC AACATTGAACGTGTTTCCCCTCTCCTTTCTCTCCCACCACAGCCCAACTATGGAAACCAGCAATATGGACCAAACAGCCAGTTCCCCACC CAGCCAGGCCAGTACCCAGCCCCCAACCCCCCGAGGCCACTCACCTCCCCCAACTACCCAGGACAGAGGATGCCCAGCCAGCCGAGCTCC GGGCAGTACCCGCCCCCCACGGTCAACATGGGGCAGTATTACAAGGTGAGTCCCAGCCTCGCCACCACCCACGGGGCCCCTTCCCTCCTA ACCACCTCACTCCCCTAACTCCACCGGGATCACTCTGACCCTGCGTGTGTTTGCCCCAAGGACAGCGAGGGGTGGGTGATTTCTGAACGT CCCCATGTGTTCAGGGCGAAGTTCGGTGGCCAGAATGTCAGAGTGGCTTTTCTCAGTTCCTATTCTCATTCGTCTCGGATGATGGTTTTT >5016_5016_3_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000422982_ZMIZ1_chr10_81036937_ENST00000478357_length(amino acids)=535AA_BP=486 MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFGGANMPNLYPGAPGAGYPPVPPGGF GQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVT PAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALM KTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRD AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTK -------------------------------------------------------------- >5016_5016_4_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000438331_ZMIZ1_chr10_81036937_ENST00000334512_length(transcript)=8635nt_BP=1941nt GCACTGCCTCTGGCACCTGGGGCAGCCGCGCCCGCGGAGTTTTCCGCCCGGCGCTGACGGCTGCTGCGCCCGCGGCTCCCCAGTGCCCCG AGTGCCCCGCGGGCCCCGCGAGCGGGAGTGGGACCCAGCCCCTAGGCAGAACCCAGGCGCCGCGCCCGGGACGCCCGCGGAGAGAGCCAC TCCCGCCCACGTCCCATTTCGCCCCTCGCGTCCGGAGTCCCCGTGGCCAGGGATTATTGGACCTGCCTGGTTTAAACTATTGTCTTAGTT AATTTTGTGCTGCTCTAACAAAATATCACAGACTGAGTAATTTATAAGCAATAGTAGCTTATTTGGCTCACAGTTCTGGAGGCTGAGAAG ATCGTGAGGCTGCATCTGGCAAGGGCCTTCTTGCTGCTTCATAACATGGCAGAAGACATCATGCGGGTGTGTGTCTGGGGAAGAGACTTA CAGAAGTGGAGTTGCTGAGTCAAAGATCTAACCATGAGCTACCCTGGCTATCCCCCGCCCCCAGGTGGCTACCCACCAGCTGCACCAGGT GGTGGTCCCTGGGGAGGTGCTGCCTACCCTCCTCCGCCCAGCATGCCCCCCATCGGGCTGGATAACGTGGCCACCTATGCGGGGCAGTTC AACCAGGACTATCTCTCGGGAATGGCGGCCAACATGTCTGGGACATTTGGAGGAGCCAACATGCCCAACCTGTACCCTGGGGCCCCTGGG GCTGGCTACCCACCAGTGCCCCCTGGCGGCTTTGGGCAGCCCCCCTCTGCCCAGCAGCCTGTTCCTCCCTATGGGATGTATCCACCCCCA GGAGGAAACCCACCCTCCAGGATGCCCTCATATCCGCCATACCCAGGGGCCCCTGTGCCGGGCCAGCCCATGCCACCCCCCGGACAGCAG CCCCCAGGGGCCTACCCTGGGCAGCCACCAGTGACCTACCCTGGTCAGCCTCCAGTGCCACTCCCTGGGCAGCAGCAGCCAGTGCCGAGC TACCCAGGATACCCGGGGTCTGGGACTGTCACCCCCGCTGTGCCCCCAACCCAGTTTGGAAGCCGAGGCACCATCACTGATGCTCCCGGC TTTGACCCCCTGCGAGATGCCGAGGTCCTGCGGAAGGCCATGAAAGGCTTCGGGACGGATGAGCAGGCCATCATTGACTGCCTGGGGAGT CGCTCCAACAAGCAGCGGCAGCAGATCCTACTTTCCTTCAAGACGGCTTACGGCAAGGATTTGATCAAAGATCTGAAATCTGAACTGTCA GGAAACTTTGAGAAGACAATCTTGGCTCTGATGAAGACCCCAGTCCTCTTTGACATTTATGAGATAAAGGAAGCCATCAAGGGGGTTGGC ACTGATGAAGCCTGCCTGATTGAGATCCTCGCTTCCCGCAGCAATGAGCACATCCGAGAATTAAACAGAGCCTACAAAGCAGAATTCAAA AAGACCCTGGAAGAGGCCATTCGAAGCGACACATCAGGGCACTTCCAGCGGCTCCTCATCTCTCTCTCTCAGGGAAACCGTGATGAAAGC ACAAACGTGGACATGTCACTCGCCCAGAGAGATGCCCAGGAGCTGTATGCGGCCGGGGAGAACCGCCTGGGAACAGACGAGTCCAAGTTC AATGCGGTTCTGTGCTCCCGGAGCCGGGCCCACCTGGTAGCAGTTTTCAATGAGTACCAGAGAATGACAGGCCGGGACATTGAGAAGAGC ATCTGCCGGGAGATGTCCGGGGACCTGGAGGAGGGCATGCTGGCCGTGGTGAAATGTCTCAAGAATACCCCAGCCTTCTTTGCGGAGAGG CTCAACAAGGCCATGAGGGGGGCAGGAACAAAGGACCGGACCCTGATTCGCATCATGGTGTCTCGCAGCGAGACCGACCTCCTGGACATC AGATCAGAGTATAAGCGGATGTACGGCAAGTCGCTGTACCACGACATCTCGCCTTGTTGTCCTCCTGGTGCGAAGAGCTCGGCCGCCTGC TGCTGCTCCGACATCAGAAGAGCCGCCAGAGCGATCCCCCTGGGAAACTCCCCATGCAGCCCCCTCTCAGCTCCATGAGCTCCATGAAAC CCACTCTGTCGCACAGTGATGGGTCGTTCCCCTATGACTCTGTCCCTTGGCAGCAGAACACCAACCAGCCTCCCGGCTCCCTTTCCGTGG TCACCACGGTTTGGGGAGTAACCAACACATCCCAGAGCCAGGTCCTTGGGAACCCTATGGCCAATGCCAACAACCCCATGAATCCAGGCG GCAACCCCATGGCGTCGGGCATGACCACCAGCAACCCAGGCCTCAACTCCCCACAGTTTGCGGGGCAGCAGCAGCAGTTCTCAGCCAAGG CTGGCCCCGCTCAGCCCTACATCCAGCAGAGCATGTATGGCCGGCCCAACTACCCCGGCAGCGGGGGCTTTGGGGCCAGTTACCCTGGGG GTCCTAACGCCCCCGCAGGCATGGGCATCCCTCCGCACACCAGGCCGCCTGCTGACTTCACTCAGCCCGCGGCAGCCGCTGCAGCAGCGG CAGTGGCAGCAGCAGCAGCCACAGCTACAGCCACAGCCACGGCCACTGTGGCAGCCCTGCAGGAGACACAGAACAAGGATATAAACCAGT ATGGACCGATGGGTCCCACCCAGGCGTATAACAGCCAATTCATGAACCAGCCCGGGCCGCGGGGGCCTGCCTCCATGGGGGGCAGCATGA ACCCCGCGAGCATGGCGGCTGGCATGACGCCCTCGGGGATGAGCGGCCCTCCCATGGGCATGAACCAGCCCCGGCCGCCCGGCATCAGCC CCTTTGGCACACACGGGCAGCGGATGCCCCAGCAGACCTACCCGGGCCCCCGGCCCCAGTCCCTTCCTATTCAGAACATAAAGAGGCCAT ACCCTGGAGAGCCCAACTATGGAAACCAGCAATATGGACCAAACAGCCAGTTCCCCACCCAGCCAGGCCAGTACCCAGCCCCCAACCCCC CGAGGCCACTCACCTCCCCCAACTACCCAGGACAGAGGATGCCCAGCCAGCCGAGCTCCGGGCAGTACCCGCCCCCCACGGTCAACATGG GGCAGTATTACAAGCCAGAACAGTTTAATGGACAAAATAACACGTTCTCGGGAAGCAGCTACAGTAACTACAGCCAAGGGAATGTCAACA GGCCTCCCAGGCCGGTTCCTGTGGCAAATTACCCCCACTCACCTGTTCCAGGGAACCCCACACCCCCCATGACCCCTGGGAGCAGCATCC CTCCATACCTGTCCCCCAGCCAAGACGTCAAACCACCCTTCCCGCCTGACATCAAGCCAAATATGAGCGCTCTGCCACCACCCCCAGCCA ACCACAATGACGAGCTGCGGCTCACATTCCCTGTGCGGGATGGCGTGGTGCTGGAGCCCTTCCGCCTGGAGCACAACCTGGCGGTCAGCA ACCATGTGTTCCACCTGCGGCCCACGGTCCACCAGACGCTGATGTGGAGGTCTGACCTGGAGCTGCAGTTCAAGTGCTACCACCACGAGG ACCGGCAGATGAACACCAACTGGCCCGCCTCGGTGCAGGTCAGCGTGAACGCCACGCCCCTCACCATTGAGCGCGGCGACAACAAGACCT CCCACAAGCCCCTGCACCTGAAGCACGTGTGCCAGCCGGGCCGCAACACCATCCAGATCACCGTCACGGCCTGCTGCTGCTCCCACCTCT TCGTGCTGCAGCTGGTACACCGGCCCTCCGTCCGCTCTGTGCTGCAAGGACTCCTCAAGAAGCGCCTCCTGCCCGCAGAGCACTGTATCA CGAAAATCAAGCGGAATTTCAGCAGCGTGGCTGCCTCCTCGGGCAACACGACCCTCAACGGGGAGGATGGGGTGGAGCAGACGGCCATCA AGGTGTCTCTGAAGTGCCCCATCACATTCCGGCGCATCCAGCTGCCTGCTCGAGGACACGATTGCAAGCATGTGCAGTGCTTTGATCTGG AGTCATACCTGCAGCTGAATTGCGAGAGAGGGACCTGGAGGTGTCCTGTGTGCAATAAAACCGCTCTGCTGGAGGGCCTGGAGGTGGATC AGTACATGTGGGGAATCCTGAATGCCATCCAACACTCCGAGTTTGAAGAGGTCACCATCGATCCCACGTGCAGCTGGCGGCCGGTGCCCA TCAAGTCGGACTTACACATCAAGGACGACCCTGATGGCATCCCCTCCAAGCGGTTCAAGACCATGAGTCCCAGCCAGATGATCATGCCCA ATGTCATGGAGATGATCGCAGCCCTGGGCCCCGGCCCGTCCCCCTATCCCCTCCCGCCTCCCCCAGGGGGCACCAACTCCAACGACTACA GCAGCCAAGGCAACAACTACCAAGGCCATGGCAACTTTGACTTCCCCCACGGGAACCCTGGAGGGACATCCATGAATGACTTCATGCACG GGCCCCCCCAGCTCTCCCACCCCCCGGACATGCCCAACAACATGGCCGCCCTCGAGAAACCCCTCAGCCACCCCATGCAGGAAACTATGC CACACGCTGGCAGCTCTGACCAGCCCCACCCCTCCATACAACAAGGTTTGCACGTACCACACCCCAGCAGCCAGTCAGGGCCTCCATTAC ATCACAGTGGGGCTCCTCCTCCTCCTCCTTCCCAGCCTCCCCGGCAGCCGCCACAGGCCGCTCCCAGCAGCCATCCACACAGCGACCTGA CCTTTAACCCCTCCTCAGCCTTAGAGGGTCAGGCCGGAGCGCAGGGAGCGTCCGACATGCCGGAGCCTTCGCTGGATCTCCTTCCCGAAC TCACAAATCCTGACGAGCTCCTGTCTTATCTGGACCCCCCCGACCTGCCGAGCAATAGTAACGATGACCTCCTGTCTCTATTTGAGAACA ACTGAGGGCCACCCGGTCGGGGCCATCCCTCCACACTCTGCATCCTACCCCACCTACCCAACACACTTTTCCACCTGGGAGCCTGTGCCC TCAGACCGCCCCGCACCAGAGCCACGGGCTGTGGGGCGGGGAGCCCTCCCCCGCTGCAGCCCTCTCAGAACAGAGGGGTAGGGAGGGTGC ACCAGTGCACCAGGAAGGCTGTGTGGGTCTGGAGCCCACGTCCCACCTCCACACCCTTGGCTTGGGCCCATGCCCAGCGCAGGCCTGAAG ACCACCCTCCCGAGAGGAACCAGCCCGGTAAGAGGGCACACGCTGATGCGGCTTCCCGGTCCCTCCGCGTGTGCCGATTCCAGATGACCT TCCAGTGTCCCCAAGGTTCTTCCATCTTCTAGACTGTAACCCTGCCTCCCTGCTTCCTGGTCCAGAGCCTCCCTCCAGTGACTGTGGAGC CTGAGAAGGCCCCCGGGCCCCAGCATGGGCCCCGAGCCTTGGAGGAGCACTGGCAGTTGGTGGCAGTGAGACCAGCCCACCCACCACCAC CCACCACAGAAAAGCACAAACCTCTGGGAAAGACAACGTCTCTCGGGGGCCAGGGGTCATCGGTTTGACCCCTGACCTATAAGCCAAGAT ACCCCATAAACACACTCAGAAAGCAGAGAAAAAGGACAAGAGTCTGTGTTTGAGAGGGGGTCTGCCATTCCTGCTTGGGGACTGGTGGGG AAGAGGGCCAGGACATCTTCTGAGCCAGGACGTCCCTGAGGCTCCACCTCCAAGCTCAGACAGGGCCCAGGCTTGGGGAACAGAGAGAGC AGGTGTACACCCAACCAAAGTGATTGTGCCCTTGGTTGGGGGGCGCGGGCATATAACCTGTCAGAAGCAAACAGGAGCGGCAACTTCTAA CTTTGCTCCAAGCCACTCTCTTTTTAAACAGCAACAATTTAAAGCTATGAAGTCACCTGGAGAAAAGGAACGTTGCTCTTGGACAGCAAG CAAACCATTTCTCTCCGTCTGTTCTGTTTTTCTCCTAGTCCCTCTCCTGCCACCTCTCCAAGACTTCCGTGGGACACCCACTTCCCTCTG TCCTAGTTCTCTTTGTCCAATCAGATGGCAAGGGCAGTGCGTGGAAAGGCCGGGGAGGTGCAGAAACCAGAGCCCAGGGCAATGGTGTCT GTCCAGCCCCTCCCTCTGTCCCTGTGCTCCAAGCTGCCCCCGGCTGCAGCCCAGGCCATGGACATGTGCACCAGTATGTACCTGCAGGCA TGGGGGGGAGGGGGGCGTGTTTCTGGGCCTGCCCCAGACACTGCCCTTGGCTGCCAGCCTACCCTGCCTGCACTCCTCCACCATCACAAT CTCACCCAAACTCCTGCTCACTCAAGCAAAAGCAGCCTCTGGCCTTCCCTCCACCGCTTTGCTCCATCTGGCTTACCACTCTCCAGGGCC TCCTGGGGAGCCTGTCCTGTGTTCACTTTGTTTCAGGCTGGTCTGTGCCCCGTGAGCCACATGGCCTAGGGTGATGCCAGGTTGTCCCGT CACTGGGGTCCCATCTGTAAATTCTTTGCGCCCTTCCCGGCTGCTGCCTGGGGCCCTTTCCTGCTCTCCCGTCCGCTGTGGGTGGTCCCC AGCTCTCCTCTGTGGGTTTTACCGGAAAGGTGGCCCCAGCTGTTGACTTCCAGTCACTGTCCCAGACGGCACAAGGTTTTCTGTAGGAAA GCTGCCATTGCCCCGGCCCCTTTTCTTCCTTTGTCCCGTTGTCGAGGTTTTTTCAAATAGCGTGTTGTTCAGTATGCAAATCAATTATTT TAAGAATCGCTTTTGTAAATATCTTTGTGAATATTTTAGTATCGTCTTTGATAATATTCAACATTTTCATGACCTGGTTATAGCCTTTGC TGGTGTTTTTAAAATACCTGGACTCAATGACAAAGACCGAGTCTTCTTTTTTTTTAAACAAAAACAAAAAAAGCAACCAGGGCTATTTGT ACAGTTGAAGGGGTGAACAGAATGGGCGGCTGTGCTGGGAGTTGGAAGACCGGGCAGCCCGCTATTTAGAGCCATCCCTCAGTCAGCTGG CAGGGACAAGCCAACGCCAGGTAGCATGTGGCCACCCTTGCCCAGTGTCTGTGGCCTGGCAAGTGGCCACGCCCTGTGTCAGACCATCTG GGAATTAAGCTCCAGACAGACTTACAGATGCCTTCCTTAGGAGTTCTTGCTTCTTGCGTTGATACTTTGCCCCAGAAAGGCCTGGGATTC ATTCTGGTTCTTATCAGGGTGTGTCCACACTCTGCTCACAGGTGGATCCACGGCTTTCCAGTGCGGAGAGTCGAGATGCTCCCTGCAGCC CAGGCCCCGGGCACCTCCTGCAACCATCTCTGGGCTCAGCACCTGAGGCGGGTTTCCTGGGTCCCCTCTCCAGCAAGCCTCCACCAGCAA GCTCGGCCCAGAGCTTCCCTTCCGGCTGGCTCTGAACCGTGCGTGGTGCCTACAGCCTGCAGTCTGGAGACAAGCTCTTCCGGAGTGCTC TGGGAGCCAGGCCAGGGTGTGAGGGAGGTGCAGAGGCATCCGGGGCGGGAGCAAGCCCCAGGTTGTGACAGGTGCAGGTAGACAACGCCC ATAAACAGAGATGGTCCTGAACTCTGGAGAGATCCTTCCCTGATCCTTTCGGACGACTACTTGGAGCCATAAGTAACCTCAGCAAAAACG AGGCCTCTGCAAGCCACTTTTCCATGCCAAGCATCCACCCGGCCCACAGGCATGTTTCTGCCGCCACTCCGCAAGATGGACAGGGAGCCA GCAGGCAGGCGGGAAGGGCCAAGTACAGGCAATCACCCCCATCTTCTTGGTTTGAAGCTTTATCCATGTATCATGTTCCGTGTAGCCATT TTATTTTTTAAGAAACTGCTAATACTTTCTCCCTAATGGAAGCCCTGATCCCCCAGAGAGCTACAGGTCTGCTCCCGACGGGCCTCGGGC CTGACCCGTCCACACAGGGCCGTGTCAACAGCAGCGACTCAAGGGACGTGTGTACATATGTAAATGAGAAATAGAGACGTGTCAACAGAT GCATTCATTTCTCTTGGAATGTGTATTGTTTTTATTTTGCGAAACAAAACAAAACAAAAAAAAAAGCTTGGAACTCCATCACGTGGAAAA ACTAGATCCTGTTGGTTATAGCATTTGTGAGTTCTCCACGTCTGTCTCTCTCGCTCATGTAATATACTCTGACCCTGAGTGGAAAGGGGT TTTTGTTCTGTTTTTATTTTACCTACATGTACTATTTAGCTTCAGTGTACTAGTCCTGCCACCTGTGTATTTTTAGGGTGCTATGGAAAT AATGAAAAGAAACGGGGATTTCAGAAGAAAATTGTAACCAAATTCATACTTTGTATAATTTTTGATATCATGATCACAGGTGATTCACAC GTACACACATAAACACACCCACCAGTGCAGCCTGAAGTAACTCCCACAGAAACCATCATCGTCTTTGTACATCGTATGTACAATGCAATC ATTTCATACTTTAAACTGGTCAAAAAACTAATTGTGATTTCTAGTCTTGCAAAGCTGTATGTAGTTAGATGATGTGACAACCTCTAATAT TTATCTAATAAATATGTATTCAGATGAAACCTGTATATTAGGTGTTCATGTGGTTATTTTGTATTTAAAGATCAAATTATTTGACTATTG >5016_5016_4_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000438331_ZMIZ1_chr10_81036937_ENST00000334512_length(amino acids)=973AA_BP=1 MLSSWCEELGRLLLLRHQKSRQSDPPGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQSQVLGN PMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPA DFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPP MGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQP SSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDI KPNMSALPPPPANHNDELRLTFPVRDGVVLEPFRLEHNLAVSNHVFHLRPTVHQTLMWRSDLELQFKCYHHEDRQMNTNWPASVQVSVNA TPLTIERGDNKTSHKPLHLKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSVAASSGNTT LNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQCFDLESYLQLNCERGTWRCPVCNKTALLEGLEVDQYMWGILNAIQHSEFEEV TIDPTCSWRPVPIKSDLHIKDDPDGIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHG NPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPP -------------------------------------------------------------- >5016_5016_5_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000537102_ZMIZ1_chr10_81036937_ENST00000334512_length(transcript)=8694nt_BP=2000nt ACCTGGGGCAGCCGCGCCCGCGGAGTTTTCCGCCCGGCGCTGACGGCTGCTGCGCCCGCGGCTCCCCAGTGCCCCGAGTGCCCCGCGGGC CCCGCGAGCGGGAGTGGGACCCAGCCCCTAGGCAGAACCCAGGCGCCGCGCCCGGGACGCCCGCGGAGAGAGCCACTCCCGCCCACGTCC CATTTCGCCCCTCGCGTCCGGAGTCCCCGTGGCCAGGTGTGTGTCTGGGGAAGAGACTTACAGAAGTGGAGTTGCTGAGTCAAAGATCTA ACCATGAGCTACCCTGGCTATCCCCCGCCCCCAGGTGGCTACCCACCAGCTGCACCAGGTTGGCTGGCACTGGCCTGGGTTCTCTCTCTA TAGTAGAAATCCTGCCATCCAGATCCTGCCACTGCCACCTTTGCTAGCACAGCTGAGCAGCCTCTGAGCAGCAAGAGAGGAGGAGGCAGG AAATTTAGGGAAGGTTCTTCCTGGAGGGTCTGGAGCCCTGGAGATGAAGAGCCGATCCGAAGCTGCCATGTAGAGGAAAGCATCTAACAG GCCAGAGGCCCCATGATGATGTCGAATGCCCATCGGGCACCCAGCTGAGCCCTGCAGGTGGTGGTCCCTGGGGAGGTGCTGCCTACCCTC CTCCGCCCAGCATGCCCCCCATCGGGCTGGATAACGTGGCCACCTATGCGGGGCAGTTCAACCAGGACTATCTCTCGGGAATGGCGGCCA ACATGTCTGGGACATTTGGAGGAGCCAACATGCCCAACCTGTACCCTGGGGCCCCTGGGGCTGGCTACCCACCAGTGCCCCCTGGCGGCT TTGGGCAGCCCCCCTCTGCCCAGCAGCCTGTTCCTCCCTATGGGATGTATCCACCCCCAGGAGGAAACCCACCCTCCAGGATGCCCTCAT ATCCGCCATACCCAGGGGCCCCTGTGCCGGGCCAGCCCATGCCACCCCCCGGACAGCAGCCCCCAGGGGCCTACCCTGGGCAGCCACCAG TGACCTACCCTGGTCAGCCTCCAGTGCCACTCCCTGGGCAGCAGCAGCCAGTGCCGAGCTACCCAGGATACCCGGGGTCTGGGACTGTCA CCCCCGCTGTGCCCCCAACCCAGTTTGGAAGCCGAGGCACCATCACTGATGCTCCCGGCTTTGACCCCCTGCGAGATGCCGAGGTCCTGC GGAAGGCCATGAAAGGCTTCGGGACGGATGAGCAGGCCATCATTGACTGCCTGGGGAGTCGCTCCAACAAGCAGCGGCAGCAGATCCTAC TTTCCTTCAAGACGGCTTACGGCAAGGATTTGATCAAAGATCTGAAATCTGAACTGTCAGGAAACTTTGAGAAGACAATCTTGGCTCTGA TGAAGACCCCAGTCCTCTTTGACATTTATGAGATAAAGGAAGCCATCAAGGGGGTTGGCACTGATGAAGCCTGCCTGATTGAGATCCTCG CTTCCCGCAGCAATGAGCACATCCGAGAATTAAACAGAGCCTACAAAGCAGAATTCAAAAAGACCCTGGAAGAGGCCATTCGAAGCGACA CATCAGGGCACTTCCAGCGGCTCCTCATCTCTCTCTCTCAGGGAAACCGTGATGAAAGCACAAACGTGGACATGTCACTCGCCCAGAGAG ATGCCCAGGAGCTGTATGCGGCCGGGGAGAACCGCCTGGGAACAGACGAGTCCAAGTTCAATGCGGTTCTGTGCTCCCGGAGCCGGGCCC ACCTGGTAGCAGTTTTCAATGAGTACCAGAGAATGACAGGCCGGGACATTGAGAAGAGCATCTGCCGGGAGATGTCCGGGGACCTGGAGG AGGGCATGCTGGCCGTGGTGAAATGTCTCAAGAATACCCCAGCCTTCTTTGCGGAGAGGCTCAACAAGGCCATGAGGGGGGCAGGAACAA AGGACCGGACCCTGATTCGCATCATGGTGTCTCGCAGCGAGACCGACCTCCTGGACATCAGATCAGAGTATAAGCGGATGTACGGCAAGT CGCTGTACCACGACATCTCGCCTTGTTGTCCTCCTGGTGCGAAGAGCTCGGCCGCCTGCTGCTGCTCCGACATCAGAAGAGCCGCCAGAG CGATCCCCCTGGGAAACTCCCCATGCAGCCCCCTCTCAGCTCCATGAGCTCCATGAAACCCACTCTGTCGCACAGTGATGGGTCGTTCCC CTATGACTCTGTCCCTTGGCAGCAGAACACCAACCAGCCTCCCGGCTCCCTTTCCGTGGTCACCACGGTTTGGGGAGTAACCAACACATC CCAGAGCCAGGTCCTTGGGAACCCTATGGCCAATGCCAACAACCCCATGAATCCAGGCGGCAACCCCATGGCGTCGGGCATGACCACCAG CAACCCAGGCCTCAACTCCCCACAGTTTGCGGGGCAGCAGCAGCAGTTCTCAGCCAAGGCTGGCCCCGCTCAGCCCTACATCCAGCAGAG CATGTATGGCCGGCCCAACTACCCCGGCAGCGGGGGCTTTGGGGCCAGTTACCCTGGGGGTCCTAACGCCCCCGCAGGCATGGGCATCCC TCCGCACACCAGGCCGCCTGCTGACTTCACTCAGCCCGCGGCAGCCGCTGCAGCAGCGGCAGTGGCAGCAGCAGCAGCCACAGCTACAGC CACAGCCACGGCCACTGTGGCAGCCCTGCAGGAGACACAGAACAAGGATATAAACCAGTATGGACCGATGGGTCCCACCCAGGCGTATAA CAGCCAATTCATGAACCAGCCCGGGCCGCGGGGGCCTGCCTCCATGGGGGGCAGCATGAACCCCGCGAGCATGGCGGCTGGCATGACGCC CTCGGGGATGAGCGGCCCTCCCATGGGCATGAACCAGCCCCGGCCGCCCGGCATCAGCCCCTTTGGCACACACGGGCAGCGGATGCCCCA GCAGACCTACCCGGGCCCCCGGCCCCAGTCCCTTCCTATTCAGAACATAAAGAGGCCATACCCTGGAGAGCCCAACTATGGAAACCAGCA ATATGGACCAAACAGCCAGTTCCCCACCCAGCCAGGCCAGTACCCAGCCCCCAACCCCCCGAGGCCACTCACCTCCCCCAACTACCCAGG ACAGAGGATGCCCAGCCAGCCGAGCTCCGGGCAGTACCCGCCCCCCACGGTCAACATGGGGCAGTATTACAAGCCAGAACAGTTTAATGG ACAAAATAACACGTTCTCGGGAAGCAGCTACAGTAACTACAGCCAAGGGAATGTCAACAGGCCTCCCAGGCCGGTTCCTGTGGCAAATTA CCCCCACTCACCTGTTCCAGGGAACCCCACACCCCCCATGACCCCTGGGAGCAGCATCCCTCCATACCTGTCCCCCAGCCAAGACGTCAA ACCACCCTTCCCGCCTGACATCAAGCCAAATATGAGCGCTCTGCCACCACCCCCAGCCAACCACAATGACGAGCTGCGGCTCACATTCCC TGTGCGGGATGGCGTGGTGCTGGAGCCCTTCCGCCTGGAGCACAACCTGGCGGTCAGCAACCATGTGTTCCACCTGCGGCCCACGGTCCA CCAGACGCTGATGTGGAGGTCTGACCTGGAGCTGCAGTTCAAGTGCTACCACCACGAGGACCGGCAGATGAACACCAACTGGCCCGCCTC GGTGCAGGTCAGCGTGAACGCCACGCCCCTCACCATTGAGCGCGGCGACAACAAGACCTCCCACAAGCCCCTGCACCTGAAGCACGTGTG CCAGCCGGGCCGCAACACCATCCAGATCACCGTCACGGCCTGCTGCTGCTCCCACCTCTTCGTGCTGCAGCTGGTACACCGGCCCTCCGT CCGCTCTGTGCTGCAAGGACTCCTCAAGAAGCGCCTCCTGCCCGCAGAGCACTGTATCACGAAAATCAAGCGGAATTTCAGCAGCGTGGC TGCCTCCTCGGGCAACACGACCCTCAACGGGGAGGATGGGGTGGAGCAGACGGCCATCAAGGTGTCTCTGAAGTGCCCCATCACATTCCG GCGCATCCAGCTGCCTGCTCGAGGACACGATTGCAAGCATGTGCAGTGCTTTGATCTGGAGTCATACCTGCAGCTGAATTGCGAGAGAGG GACCTGGAGGTGTCCTGTGTGCAATAAAACCGCTCTGCTGGAGGGCCTGGAGGTGGATCAGTACATGTGGGGAATCCTGAATGCCATCCA ACACTCCGAGTTTGAAGAGGTCACCATCGATCCCACGTGCAGCTGGCGGCCGGTGCCCATCAAGTCGGACTTACACATCAAGGACGACCC TGATGGCATCCCCTCCAAGCGGTTCAAGACCATGAGTCCCAGCCAGATGATCATGCCCAATGTCATGGAGATGATCGCAGCCCTGGGCCC CGGCCCGTCCCCCTATCCCCTCCCGCCTCCCCCAGGGGGCACCAACTCCAACGACTACAGCAGCCAAGGCAACAACTACCAAGGCCATGG CAACTTTGACTTCCCCCACGGGAACCCTGGAGGGACATCCATGAATGACTTCATGCACGGGCCCCCCCAGCTCTCCCACCCCCCGGACAT GCCCAACAACATGGCCGCCCTCGAGAAACCCCTCAGCCACCCCATGCAGGAAACTATGCCACACGCTGGCAGCTCTGACCAGCCCCACCC CTCCATACAACAAGGTTTGCACGTACCACACCCCAGCAGCCAGTCAGGGCCTCCATTACATCACAGTGGGGCTCCTCCTCCTCCTCCTTC CCAGCCTCCCCGGCAGCCGCCACAGGCCGCTCCCAGCAGCCATCCACACAGCGACCTGACCTTTAACCCCTCCTCAGCCTTAGAGGGTCA GGCCGGAGCGCAGGGAGCGTCCGACATGCCGGAGCCTTCGCTGGATCTCCTTCCCGAACTCACAAATCCTGACGAGCTCCTGTCTTATCT GGACCCCCCCGACCTGCCGAGCAATAGTAACGATGACCTCCTGTCTCTATTTGAGAACAACTGAGGGCCACCCGGTCGGGGCCATCCCTC CACACTCTGCATCCTACCCCACCTACCCAACACACTTTTCCACCTGGGAGCCTGTGCCCTCAGACCGCCCCGCACCAGAGCCACGGGCTG TGGGGCGGGGAGCCCTCCCCCGCTGCAGCCCTCTCAGAACAGAGGGGTAGGGAGGGTGCACCAGTGCACCAGGAAGGCTGTGTGGGTCTG GAGCCCACGTCCCACCTCCACACCCTTGGCTTGGGCCCATGCCCAGCGCAGGCCTGAAGACCACCCTCCCGAGAGGAACCAGCCCGGTAA GAGGGCACACGCTGATGCGGCTTCCCGGTCCCTCCGCGTGTGCCGATTCCAGATGACCTTCCAGTGTCCCCAAGGTTCTTCCATCTTCTA GACTGTAACCCTGCCTCCCTGCTTCCTGGTCCAGAGCCTCCCTCCAGTGACTGTGGAGCCTGAGAAGGCCCCCGGGCCCCAGCATGGGCC CCGAGCCTTGGAGGAGCACTGGCAGTTGGTGGCAGTGAGACCAGCCCACCCACCACCACCCACCACAGAAAAGCACAAACCTCTGGGAAA GACAACGTCTCTCGGGGGCCAGGGGTCATCGGTTTGACCCCTGACCTATAAGCCAAGATACCCCATAAACACACTCAGAAAGCAGAGAAA AAGGACAAGAGTCTGTGTTTGAGAGGGGGTCTGCCATTCCTGCTTGGGGACTGGTGGGGAAGAGGGCCAGGACATCTTCTGAGCCAGGAC GTCCCTGAGGCTCCACCTCCAAGCTCAGACAGGGCCCAGGCTTGGGGAACAGAGAGAGCAGGTGTACACCCAACCAAAGTGATTGTGCCC TTGGTTGGGGGGCGCGGGCATATAACCTGTCAGAAGCAAACAGGAGCGGCAACTTCTAACTTTGCTCCAAGCCACTCTCTTTTTAAACAG CAACAATTTAAAGCTATGAAGTCACCTGGAGAAAAGGAACGTTGCTCTTGGACAGCAAGCAAACCATTTCTCTCCGTCTGTTCTGTTTTT CTCCTAGTCCCTCTCCTGCCACCTCTCCAAGACTTCCGTGGGACACCCACTTCCCTCTGTCCTAGTTCTCTTTGTCCAATCAGATGGCAA GGGCAGTGCGTGGAAAGGCCGGGGAGGTGCAGAAACCAGAGCCCAGGGCAATGGTGTCTGTCCAGCCCCTCCCTCTGTCCCTGTGCTCCA AGCTGCCCCCGGCTGCAGCCCAGGCCATGGACATGTGCACCAGTATGTACCTGCAGGCATGGGGGGGAGGGGGGCGTGTTTCTGGGCCTG CCCCAGACACTGCCCTTGGCTGCCAGCCTACCCTGCCTGCACTCCTCCACCATCACAATCTCACCCAAACTCCTGCTCACTCAAGCAAAA GCAGCCTCTGGCCTTCCCTCCACCGCTTTGCTCCATCTGGCTTACCACTCTCCAGGGCCTCCTGGGGAGCCTGTCCTGTGTTCACTTTGT TTCAGGCTGGTCTGTGCCCCGTGAGCCACATGGCCTAGGGTGATGCCAGGTTGTCCCGTCACTGGGGTCCCATCTGTAAATTCTTTGCGC CCTTCCCGGCTGCTGCCTGGGGCCCTTTCCTGCTCTCCCGTCCGCTGTGGGTGGTCCCCAGCTCTCCTCTGTGGGTTTTACCGGAAAGGT GGCCCCAGCTGTTGACTTCCAGTCACTGTCCCAGACGGCACAAGGTTTTCTGTAGGAAAGCTGCCATTGCCCCGGCCCCTTTTCTTCCTT TGTCCCGTTGTCGAGGTTTTTTCAAATAGCGTGTTGTTCAGTATGCAAATCAATTATTTTAAGAATCGCTTTTGTAAATATCTTTGTGAA TATTTTAGTATCGTCTTTGATAATATTCAACATTTTCATGACCTGGTTATAGCCTTTGCTGGTGTTTTTAAAATACCTGGACTCAATGAC AAAGACCGAGTCTTCTTTTTTTTTAAACAAAAACAAAAAAAGCAACCAGGGCTATTTGTACAGTTGAAGGGGTGAACAGAATGGGCGGCT GTGCTGGGAGTTGGAAGACCGGGCAGCCCGCTATTTAGAGCCATCCCTCAGTCAGCTGGCAGGGACAAGCCAACGCCAGGTAGCATGTGG CCACCCTTGCCCAGTGTCTGTGGCCTGGCAAGTGGCCACGCCCTGTGTCAGACCATCTGGGAATTAAGCTCCAGACAGACTTACAGATGC CTTCCTTAGGAGTTCTTGCTTCTTGCGTTGATACTTTGCCCCAGAAAGGCCTGGGATTCATTCTGGTTCTTATCAGGGTGTGTCCACACT CTGCTCACAGGTGGATCCACGGCTTTCCAGTGCGGAGAGTCGAGATGCTCCCTGCAGCCCAGGCCCCGGGCACCTCCTGCAACCATCTCT GGGCTCAGCACCTGAGGCGGGTTTCCTGGGTCCCCTCTCCAGCAAGCCTCCACCAGCAAGCTCGGCCCAGAGCTTCCCTTCCGGCTGGCT CTGAACCGTGCGTGGTGCCTACAGCCTGCAGTCTGGAGACAAGCTCTTCCGGAGTGCTCTGGGAGCCAGGCCAGGGTGTGAGGGAGGTGC AGAGGCATCCGGGGCGGGAGCAAGCCCCAGGTTGTGACAGGTGCAGGTAGACAACGCCCATAAACAGAGATGGTCCTGAACTCTGGAGAG ATCCTTCCCTGATCCTTTCGGACGACTACTTGGAGCCATAAGTAACCTCAGCAAAAACGAGGCCTCTGCAAGCCACTTTTCCATGCCAAG CATCCACCCGGCCCACAGGCATGTTTCTGCCGCCACTCCGCAAGATGGACAGGGAGCCAGCAGGCAGGCGGGAAGGGCCAAGTACAGGCA ATCACCCCCATCTTCTTGGTTTGAAGCTTTATCCATGTATCATGTTCCGTGTAGCCATTTTATTTTTTAAGAAACTGCTAATACTTTCTC CCTAATGGAAGCCCTGATCCCCCAGAGAGCTACAGGTCTGCTCCCGACGGGCCTCGGGCCTGACCCGTCCACACAGGGCCGTGTCAACAG CAGCGACTCAAGGGACGTGTGTACATATGTAAATGAGAAATAGAGACGTGTCAACAGATGCATTCATTTCTCTTGGAATGTGTATTGTTT TTATTTTGCGAAACAAAACAAAACAAAAAAAAAAGCTTGGAACTCCATCACGTGGAAAAACTAGATCCTGTTGGTTATAGCATTTGTGAG TTCTCCACGTCTGTCTCTCTCGCTCATGTAATATACTCTGACCCTGAGTGGAAAGGGGTTTTTGTTCTGTTTTTATTTTACCTACATGTA CTATTTAGCTTCAGTGTACTAGTCCTGCCACCTGTGTATTTTTAGGGTGCTATGGAAATAATGAAAAGAAACGGGGATTTCAGAAGAAAA TTGTAACCAAATTCATACTTTGTATAATTTTTGATATCATGATCACAGGTGATTCACACGTACACACATAAACACACCCACCAGTGCAGC CTGAAGTAACTCCCACAGAAACCATCATCGTCTTTGTACATCGTATGTACAATGCAATCATTTCATACTTTAAACTGGTCAAAAAACTAA TTGTGATTTCTAGTCTTGCAAAGCTGTATGTAGTTAGATGATGTGACAACCTCTAATATTTATCTAATAAATATGTATTCAGATGAAACC TGTATATTAGGTGTTCATGTGGTTATTTTGTATTTAAAGATCAAATTATTTGACTATTGCTAGACATTTCTATACTCTGTTGTAACACTG >5016_5016_5_ANXA11-ZMIZ1_ANXA11_chr10_81917396_ENST00000537102_ZMIZ1_chr10_81036937_ENST00000334512_length(amino acids)=973AA_BP=1 MLSSWCEELGRLLLLRHQKSRQSDPPGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQSQVLGN PMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPA DFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPP MGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQP SSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDI KPNMSALPPPPANHNDELRLTFPVRDGVVLEPFRLEHNLAVSNHVFHLRPTVHQTLMWRSDLELQFKCYHHEDRQMNTNWPASVQVSVNA TPLTIERGDNKTSHKPLHLKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSVAASSGNTT LNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQCFDLESYLQLNCERGTWRCPVCNKTALLEGLEVDQYMWGILNAIQHSEFEEV TIDPTCSWRPVPIKSDLHIKDDPDGIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHG NPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPP -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for ANXA11-ZMIZ1 |
Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
- Retained PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
- Lost PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
- Retained PPIs, but lost function due to frame-shift fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for ANXA11-ZMIZ1 |
Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for ANXA11-ZMIZ1 |
Diseases associated with fusion partners. (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | ANXA11 | C4693381 | AMYOTROPHIC LATERAL SCLEROSIS 23 | 2 | GENOMICS_ENGLAND;UNIPROT |
Hgene | ANXA11 | C0002736 | Amyotrophic Lateral Sclerosis | 1 | ORPHANET |
Hgene | ANXA11 | C0036202 | Sarcoidosis | 1 | CTD_human |
Tgene | C0025958 | Microcephaly | 2 | GENOMICS_ENGLAND | |
Tgene | C0232466 | Feeding difficulties | 2 | GENOMICS_ENGLAND | |
Tgene | C0243050 | Cardiovascular Abnormalities | 2 | GENOMICS_ENGLAND | |
Tgene | C0262361 | Growth abnormality | 2 | GENOMICS_ENGLAND | |
Tgene | C0557874 | Global developmental delay | 2 | GENOMICS_ENGLAND | |
Tgene | C3714756 | Intellectual Disability | 2 | GENOMICS_ENGLAND | |
Tgene | C4021790 | Abnormality of the skeletal system | 2 | GENOMICS_ENGLAND | |
Tgene | C4021817 | Abnormality of head or neck | 2 | GENOMICS_ENGLAND | |
Tgene | C4021821 | Abnormality of the urinary system | 2 | GENOMICS_ENGLAND | |
Tgene | C0007570 | Celiac Disease | 1 | CTD_human | |
Tgene | C0009402 | Colorectal Carcinoma | 1 | CTD_human | |
Tgene | C0009404 | Colorectal Neoplasms | 1 | CTD_human | |
Tgene | C0036572 | Seizures | 1 | GENOMICS_ENGLAND |