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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ACACA-MED24 (FusionGDB2 ID:HG31TG9862)

Fusion Gene Summary for ACACA-MED24

check button Fusion gene summary
Fusion gene informationFusion gene name: ACACA-MED24
Fusion gene ID: hg31tg9862
HgeneTgene
Gene symbol

ACACA

MED24

Gene ID

31

9862

Gene nameacetyl-CoA carboxylase alphamediator complex subunit 24
SynonymsACAC|ACACAD|ACC|ACC1|ACCAARC100|CRSP100|CRSP4|DRIP100|MED5|THRAP4|TRAP100
Cytomap('ACACA')('MED24')

17q12

17q21.1

Type of geneprotein-codingprotein-coding
Descriptionacetyl-CoA carboxylase 1ACC-alphaacetyl-Coenzyme A carboxylase alphamediator of RNA polymerase II transcription subunit 24CRSP complex subunit 4activator-recruited cofactor 100 kDa componentcofactor required for Sp1 transcriptional activation subunit 4cofactor required for Sp1 transcriptional activation, subunit 4, 10
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000353139, ENST00000416895, 
ENST00000589665, ENST00000335166, 
ENST00000360679, ENST00000361253, 
ENST00000394406, ENST00000588142, 
Fusion gene scores* DoF score44 X 35 X 17=2618016 X 15 X 7=1680
# samples 5123
** MAII scorelog2(51/26180*10)=-5.68182403997375
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(23/1680*10)=-2.86875546672175
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ACACA [Title/Abstract] AND MED24 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointACACA(35766352)-MED24(38209888), # samples:2
Anticipated loss of major functional domain due to fusion event.ACACA-MED24 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ACACA-MED24 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ACACA-MED24 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ACACA-MED24 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMED24

GO:0006367

transcription initiation from RNA polymerase II promoter

12218053

TgeneMED24

GO:0045893

positive regulation of transcription, DNA-templated

10198638


check buttonFusion gene breakpoints across ACACA (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across MED24 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-D8-A1XJ-01AACACAchr17

35766352

-MED24chr17

38209888

-
ChimerDB4BRCATCGA-D8-A1XJ-01AACACAchr17

35766352

-MED24chr17

38209910

-


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Fusion Gene ORF analysis for ACACA-MED24

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000353139ENST00000356271ACACAchr17

35766352

-MED24chr17

38209888

-
5CDS-5UTRENST00000353139ENST00000394127ACACAchr17

35766352

-MED24chr17

38209888

-
5CDS-5UTRENST00000353139ENST00000394127ACACAchr17

35766352

-MED24chr17

38209910

-
5CDS-5UTRENST00000353139ENST00000394128ACACAchr17

35766352

-MED24chr17

38209888

-
5CDS-5UTRENST00000353139ENST00000479829ACACAchr17

35766352

-MED24chr17

38209888

-
5CDS-intronENST00000353139ENST00000356271ACACAchr17

35766352

-MED24chr17

38209910

-
5CDS-intronENST00000353139ENST00000394128ACACAchr17

35766352

-MED24chr17

38209910

-
5CDS-intronENST00000353139ENST00000479829ACACAchr17

35766352

-MED24chr17

38209910

-
5CDS-intronENST00000353139ENST00000501516ACACAchr17

35766352

-MED24chr17

38209888

-
5CDS-intronENST00000353139ENST00000501516ACACAchr17

35766352

-MED24chr17

38209910

-
5UTR-3CDSENST00000416895ENST00000394126ACACAchr17

35766352

-MED24chr17

38209888

-
5UTR-3CDSENST00000416895ENST00000394126ACACAchr17

35766352

-MED24chr17

38209910

-
5UTR-3CDSENST00000589665ENST00000394126ACACAchr17

35766352

-MED24chr17

38209888

-
5UTR-3CDSENST00000589665ENST00000394126ACACAchr17

35766352

-MED24chr17

38209910

-
5UTR-5UTRENST00000416895ENST00000356271ACACAchr17

35766352

-MED24chr17

38209888

-
5UTR-5UTRENST00000416895ENST00000394127ACACAchr17

35766352

-MED24chr17

38209888

-
5UTR-5UTRENST00000416895ENST00000394127ACACAchr17

35766352

-MED24chr17

38209910

-
5UTR-5UTRENST00000416895ENST00000394128ACACAchr17

35766352

-MED24chr17

38209888

-
5UTR-5UTRENST00000416895ENST00000479829ACACAchr17

35766352

-MED24chr17

38209888

-
5UTR-5UTRENST00000589665ENST00000356271ACACAchr17

35766352

-MED24chr17

38209888

-
5UTR-5UTRENST00000589665ENST00000394127ACACAchr17

35766352

-MED24chr17

38209888

-
5UTR-5UTRENST00000589665ENST00000394127ACACAchr17

35766352

-MED24chr17

38209910

-
5UTR-5UTRENST00000589665ENST00000394128ACACAchr17

35766352

-MED24chr17

38209888

-
5UTR-5UTRENST00000589665ENST00000479829ACACAchr17

35766352

-MED24chr17

38209888

-
5UTR-intronENST00000416895ENST00000356271ACACAchr17

35766352

-MED24chr17

38209910

-
5UTR-intronENST00000416895ENST00000394128ACACAchr17

35766352

-MED24chr17

38209910

-
5UTR-intronENST00000416895ENST00000479829ACACAchr17

35766352

-MED24chr17

38209910

-
5UTR-intronENST00000416895ENST00000501516ACACAchr17

35766352

-MED24chr17

38209888

-
5UTR-intronENST00000416895ENST00000501516ACACAchr17

35766352

-MED24chr17

38209910

-
5UTR-intronENST00000589665ENST00000356271ACACAchr17

35766352

-MED24chr17

38209910

-
5UTR-intronENST00000589665ENST00000394128ACACAchr17

35766352

-MED24chr17

38209910

-
5UTR-intronENST00000589665ENST00000479829ACACAchr17

35766352

-MED24chr17

38209910

-
5UTR-intronENST00000589665ENST00000501516ACACAchr17

35766352

-MED24chr17

38209888

-
5UTR-intronENST00000589665ENST00000501516ACACAchr17

35766352

-MED24chr17

38209910

-
In-frameENST00000353139ENST00000394126ACACAchr17

35766352

-MED24chr17

38209888

-
In-frameENST00000353139ENST00000394126ACACAchr17

35766352

-MED24chr17

38209910

-
intron-3CDSENST00000335166ENST00000394126ACACAchr17

35766352

-MED24chr17

38209888

-
intron-3CDSENST00000335166ENST00000394126ACACAchr17

35766352

-MED24chr17

38209910

-
intron-3CDSENST00000360679ENST00000394126ACACAchr17

35766352

-MED24chr17

38209888

-
intron-3CDSENST00000360679ENST00000394126ACACAchr17

35766352

-MED24chr17

38209910

-
intron-3CDSENST00000361253ENST00000394126ACACAchr17

35766352

-MED24chr17

38209888

-
intron-3CDSENST00000361253ENST00000394126ACACAchr17

35766352

-MED24chr17

38209910

-
intron-3CDSENST00000394406ENST00000394126ACACAchr17

35766352

-MED24chr17

38209888

-
intron-3CDSENST00000394406ENST00000394126ACACAchr17

35766352

-MED24chr17

38209910

-
intron-3CDSENST00000588142ENST00000394126ACACAchr17

35766352

-MED24chr17

38209888

-
intron-3CDSENST00000588142ENST00000394126ACACAchr17

35766352

-MED24chr17

38209910

-
intron-5UTRENST00000335166ENST00000356271ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000335166ENST00000394127ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000335166ENST00000394127ACACAchr17

35766352

-MED24chr17

38209910

-
intron-5UTRENST00000335166ENST00000394128ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000335166ENST00000479829ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000360679ENST00000356271ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000360679ENST00000394127ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000360679ENST00000394127ACACAchr17

35766352

-MED24chr17

38209910

-
intron-5UTRENST00000360679ENST00000394128ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000360679ENST00000479829ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000361253ENST00000356271ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000361253ENST00000394127ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000361253ENST00000394127ACACAchr17

35766352

-MED24chr17

38209910

-
intron-5UTRENST00000361253ENST00000394128ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000361253ENST00000479829ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000394406ENST00000356271ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000394406ENST00000394127ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000394406ENST00000394127ACACAchr17

35766352

-MED24chr17

38209910

-
intron-5UTRENST00000394406ENST00000394128ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000394406ENST00000479829ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000588142ENST00000356271ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000588142ENST00000394127ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000588142ENST00000394127ACACAchr17

35766352

-MED24chr17

38209910

-
intron-5UTRENST00000588142ENST00000394128ACACAchr17

35766352

-MED24chr17

38209888

-
intron-5UTRENST00000588142ENST00000479829ACACAchr17

35766352

-MED24chr17

38209888

-
intron-intronENST00000335166ENST00000356271ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000335166ENST00000394128ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000335166ENST00000479829ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000335166ENST00000501516ACACAchr17

35766352

-MED24chr17

38209888

-
intron-intronENST00000335166ENST00000501516ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000360679ENST00000356271ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000360679ENST00000394128ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000360679ENST00000479829ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000360679ENST00000501516ACACAchr17

35766352

-MED24chr17

38209888

-
intron-intronENST00000360679ENST00000501516ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000361253ENST00000356271ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000361253ENST00000394128ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000361253ENST00000479829ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000361253ENST00000501516ACACAchr17

35766352

-MED24chr17

38209888

-
intron-intronENST00000361253ENST00000501516ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000394406ENST00000356271ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000394406ENST00000394128ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000394406ENST00000479829ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000394406ENST00000501516ACACAchr17

35766352

-MED24chr17

38209888

-
intron-intronENST00000394406ENST00000501516ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000588142ENST00000356271ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000588142ENST00000394128ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000588142ENST00000479829ACACAchr17

35766352

-MED24chr17

38209910

-
intron-intronENST00000588142ENST00000501516ACACAchr17

35766352

-MED24chr17

38209888

-
intron-intronENST00000588142ENST00000501516ACACAchr17

35766352

-MED24chr17

38209910

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000353139ACACAchr1735766352-ENST00000394126MED24chr1738209888-395952014002425341
ENST00000353139ACACAchr1735766352-ENST00000394126MED24chr1738209910-398152014002425341

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000353139ENST00000394126ACACAchr1735766352-MED24chr1738209888-0.0072703690.9927296
ENST00000353139ENST00000394126ACACAchr1735766352-MED24chr1738209910-0.0083603480.9916397

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Fusion Genomic Features for ACACA-MED24


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ACACA-MED24


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:35766352/chr17:38209888)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMED24chr17:35766352chr17:38209888ENST00000356271025128_1320977.0MotifNote=LXXLL motif 1
TgeneMED24chr17:35766352chr17:38209888ENST00000356271025344_3480977.0MotifNote=LXXLL motif 2
TgeneMED24chr17:35766352chr17:38209888ENST00000356271025448_4520977.0MotifNote=LXXLL motif 3
TgeneMED24chr17:35766352chr17:38209888ENST00000356271025557_5610977.0MotifNote=LXXLL motif 4
TgeneMED24chr17:35766352chr17:38209888ENST00000356271025788_7920977.0MotifNote=LXXLL motif 5
TgeneMED24chr17:35766352chr17:38209888ENST00000356271025857_8610977.0MotifNote=LXXLL motif 6
TgeneMED24chr17:35766352chr17:38209888ENST00000394127025128_1320977.0MotifNote=LXXLL motif 1
TgeneMED24chr17:35766352chr17:38209888ENST00000394127025344_3480977.0MotifNote=LXXLL motif 2
TgeneMED24chr17:35766352chr17:38209888ENST00000394127025448_4520977.0MotifNote=LXXLL motif 3
TgeneMED24chr17:35766352chr17:38209888ENST00000394127025557_5610977.0MotifNote=LXXLL motif 4
TgeneMED24chr17:35766352chr17:38209888ENST00000394127025788_7920977.0MotifNote=LXXLL motif 5
TgeneMED24chr17:35766352chr17:38209888ENST00000394127025857_8610977.0MotifNote=LXXLL motif 6
TgeneMED24chr17:35766352chr17:38209888ENST00000394128026128_1320990.0MotifNote=LXXLL motif 1
TgeneMED24chr17:35766352chr17:38209888ENST00000394128026344_3480990.0MotifNote=LXXLL motif 2
TgeneMED24chr17:35766352chr17:38209888ENST00000394128026448_4520990.0MotifNote=LXXLL motif 3
TgeneMED24chr17:35766352chr17:38209888ENST00000394128026557_5610990.0MotifNote=LXXLL motif 4
TgeneMED24chr17:35766352chr17:38209888ENST00000394128026788_7920990.0MotifNote=LXXLL motif 5
TgeneMED24chr17:35766352chr17:38209888ENST00000394128026857_8610990.0MotifNote=LXXLL motif 6
TgeneMED24chr17:35766352chr17:38209910ENST00000356271025128_1320977.0MotifNote=LXXLL motif 1
TgeneMED24chr17:35766352chr17:38209910ENST00000356271025344_3480977.0MotifNote=LXXLL motif 2
TgeneMED24chr17:35766352chr17:38209910ENST00000356271025448_4520977.0MotifNote=LXXLL motif 3
TgeneMED24chr17:35766352chr17:38209910ENST00000356271025557_5610977.0MotifNote=LXXLL motif 4
TgeneMED24chr17:35766352chr17:38209910ENST00000356271025788_7920977.0MotifNote=LXXLL motif 5
TgeneMED24chr17:35766352chr17:38209910ENST00000356271025857_8610977.0MotifNote=LXXLL motif 6
TgeneMED24chr17:35766352chr17:38209910ENST00000394127025128_1320977.0MotifNote=LXXLL motif 1
TgeneMED24chr17:35766352chr17:38209910ENST00000394127025344_3480977.0MotifNote=LXXLL motif 2
TgeneMED24chr17:35766352chr17:38209910ENST00000394127025448_4520977.0MotifNote=LXXLL motif 3
TgeneMED24chr17:35766352chr17:38209910ENST00000394127025557_5610977.0MotifNote=LXXLL motif 4
TgeneMED24chr17:35766352chr17:38209910ENST00000394127025788_7920977.0MotifNote=LXXLL motif 5
TgeneMED24chr17:35766352chr17:38209910ENST00000394127025857_8610977.0MotifNote=LXXLL motif 6
TgeneMED24chr17:35766352chr17:38209910ENST00000394128026128_1320990.0MotifNote=LXXLL motif 1
TgeneMED24chr17:35766352chr17:38209910ENST00000394128026344_3480990.0MotifNote=LXXLL motif 2
TgeneMED24chr17:35766352chr17:38209910ENST00000394128026448_4520990.0MotifNote=LXXLL motif 3
TgeneMED24chr17:35766352chr17:38209910ENST00000394128026557_5610990.0MotifNote=LXXLL motif 4
TgeneMED24chr17:35766352chr17:38209910ENST00000394128026788_7920990.0MotifNote=LXXLL motif 5
TgeneMED24chr17:35766352chr17:38209910ENST00000394128026857_8610990.0MotifNote=LXXLL motif 6

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneACACAchr17:35766352chr17:38209888ENST00000335166-155117_61802269.0DomainBiotin carboxylation
HgeneACACAchr17:35766352chr17:38209888ENST00000335166-1551576_191402269.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35766352chr17:38209888ENST00000335166-1551918_223402269.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35766352chr17:38209888ENST00000335166-155275_46602269.0DomainATP-grasp
HgeneACACAchr17:35766352chr17:38209888ENST00000335166-155745_81902269.0DomainBiotinyl-binding
HgeneACACAchr17:35766352chr17:38209888ENST00000353139-156117_618122384.0DomainBiotin carboxylation
HgeneACACAchr17:35766352chr17:38209888ENST00000353139-1561576_1914122384.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35766352chr17:38209888ENST00000353139-1561918_2234122384.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35766352chr17:38209888ENST00000353139-156275_466122384.0DomainATP-grasp
HgeneACACAchr17:35766352chr17:38209888ENST00000353139-156745_819122384.0DomainBiotinyl-binding
HgeneACACAchr17:35766352chr17:38209888ENST00000360679-154117_61802289.0DomainBiotin carboxylation
HgeneACACAchr17:35766352chr17:38209888ENST00000360679-1541576_191402289.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35766352chr17:38209888ENST00000360679-1541918_223402289.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35766352chr17:38209888ENST00000360679-154275_46602289.0DomainATP-grasp
HgeneACACAchr17:35766352chr17:38209888ENST00000360679-154745_81902289.0DomainBiotinyl-binding
HgeneACACAchr17:35766352chr17:38209888ENST00000394406-156117_61802347.0DomainBiotin carboxylation
HgeneACACAchr17:35766352chr17:38209888ENST00000394406-1561576_191402347.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35766352chr17:38209888ENST00000394406-1561918_223402347.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35766352chr17:38209888ENST00000394406-156275_46602347.0DomainATP-grasp
HgeneACACAchr17:35766352chr17:38209888ENST00000394406-156745_81902347.0DomainBiotinyl-binding
HgeneACACAchr17:35766352chr17:38209910ENST00000335166-155117_61802269.0DomainBiotin carboxylation
HgeneACACAchr17:35766352chr17:38209910ENST00000335166-1551576_191402269.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35766352chr17:38209910ENST00000335166-1551918_223402269.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35766352chr17:38209910ENST00000335166-155275_46602269.0DomainATP-grasp
HgeneACACAchr17:35766352chr17:38209910ENST00000335166-155745_81902269.0DomainBiotinyl-binding
HgeneACACAchr17:35766352chr17:38209910ENST00000353139-156117_618122384.0DomainBiotin carboxylation
HgeneACACAchr17:35766352chr17:38209910ENST00000353139-1561576_1914122384.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35766352chr17:38209910ENST00000353139-1561918_2234122384.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35766352chr17:38209910ENST00000353139-156275_466122384.0DomainATP-grasp
HgeneACACAchr17:35766352chr17:38209910ENST00000353139-156745_819122384.0DomainBiotinyl-binding
HgeneACACAchr17:35766352chr17:38209910ENST00000360679-154117_61802289.0DomainBiotin carboxylation
HgeneACACAchr17:35766352chr17:38209910ENST00000360679-1541576_191402289.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35766352chr17:38209910ENST00000360679-1541918_223402289.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35766352chr17:38209910ENST00000360679-154275_46602289.0DomainATP-grasp
HgeneACACAchr17:35766352chr17:38209910ENST00000360679-154745_81902289.0DomainBiotinyl-binding
HgeneACACAchr17:35766352chr17:38209910ENST00000394406-156117_61802347.0DomainBiotin carboxylation
HgeneACACAchr17:35766352chr17:38209910ENST00000394406-1561576_191402347.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35766352chr17:38209910ENST00000394406-1561918_223402347.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35766352chr17:38209910ENST00000394406-156275_46602347.0DomainATP-grasp
HgeneACACAchr17:35766352chr17:38209910ENST00000394406-156745_81902347.0DomainBiotinyl-binding
HgeneACACAchr17:35766352chr17:38209888ENST00000335166-155315_32002269.0Nucleotide bindingATP
HgeneACACAchr17:35766352chr17:38209888ENST00000353139-156315_320122384.0Nucleotide bindingATP
HgeneACACAchr17:35766352chr17:38209888ENST00000360679-154315_32002289.0Nucleotide bindingATP
HgeneACACAchr17:35766352chr17:38209888ENST00000394406-156315_32002347.0Nucleotide bindingATP
HgeneACACAchr17:35766352chr17:38209910ENST00000335166-155315_32002269.0Nucleotide bindingATP
HgeneACACAchr17:35766352chr17:38209910ENST00000353139-156315_320122384.0Nucleotide bindingATP
HgeneACACAchr17:35766352chr17:38209910ENST00000360679-154315_32002289.0Nucleotide bindingATP
HgeneACACAchr17:35766352chr17:38209910ENST00000394406-156315_32002347.0Nucleotide bindingATP
HgeneACACAchr17:35766352chr17:38209888ENST00000335166-1551576_223402269.0RegionCarboxyltransferase
HgeneACACAchr17:35766352chr17:38209888ENST00000353139-1561576_2234122384.0RegionCarboxyltransferase
HgeneACACAchr17:35766352chr17:38209888ENST00000360679-1541576_223402289.0RegionCarboxyltransferase
HgeneACACAchr17:35766352chr17:38209888ENST00000394406-1561576_223402347.0RegionCarboxyltransferase
HgeneACACAchr17:35766352chr17:38209910ENST00000335166-1551576_223402269.0RegionCarboxyltransferase
HgeneACACAchr17:35766352chr17:38209910ENST00000353139-1561576_2234122384.0RegionCarboxyltransferase
HgeneACACAchr17:35766352chr17:38209910ENST00000360679-1541576_223402289.0RegionCarboxyltransferase
HgeneACACAchr17:35766352chr17:38209910ENST00000394406-1561576_223402347.0RegionCarboxyltransferase


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Fusion Gene Sequence for ACACA-MED24


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>1164_1164_1_ACACA-MED24_ACACA_chr17_35766352_ENST00000353139_MED24_chr17_38209888_ENST00000394126_length(transcript)=3959nt_BP=520nt
GCCCTCTTGGCCTTTTCCCGGTCCCCGCCGCGCGCCTGCTGCTGTCCCCGTGCCCGAGGACTGGGAGGATGGGGCTGAGCCGCTTGCCTG
ACTTTTGATCCGACCAGTAATCACTTTGCCCGTGTGGCGCGTGGCCCGTTGCCTGAGGCTTCCTGGCGCGTGGGGCTGTTTGGTCCCCTC
CGGAGTGCGGTGAGGCGGGCCGAGCCGGGACTGCCTGGGTTTGGGGATAACGTTCCCATCTCCACCCCTGTTGCAGCAAGGGAAATTGAG
GCTGAGGGAACTGGGCCCAGGGACGGCGAGCCGTGGCTGCCTCTCCAGTCCGGGCCCCGAAGGGCTGCTCGTGGATGAACCAGACTGATT
TTAAGGGGTGAAGAGGGTGCGTTTCAATCAGATGCTTCTGGAACGTCGAAATTGTCTTCTTTGGAAAGAACCATCCCCTCTTTGGGCTTC
AGAGGCCCAAATTGAGGCGCAATGATGAGAGGATGTGGTGGTCTACTCTGATGTCAATCTTGAGGGCTAGGTGTCGGAACTGGTGAAGGT
GTCAGCCATGTCCAGCCCCAAGGTGGTTCTGGCCATCACGGACCTCAGCCTGCCCCTGGGCCGCCAGGTGGCTGCTAAAGCCATTGCTGC
ACTCTGAGGGGCTTGGCATGGCCGCAGTGGGGGCTGGGGACTGGCGCAGCCCCAGGCGCCTCCAAGGGAAGCAGTGAGGAAAGATGAGGC
ATCGTGCCTCACATCCGCTCCACATGGTGCAAGAGCCTCTAGCGGCTTCCAGTTCCCCGCTCCTGACTCCTGACCTCCAGGATGTCTCCC
GGTTTCTTCTTTCAAAATTTCCTCTCCATCTGCTGGCACCTGAGGAGAGTGAGCAGCCTGGACCACAAGCCCAGTGGTCACCCCTGTGTG
CGCCCGCCCCAGCCCAGGAGTAGTCTTACCTCTGAGGAACTTTCTAGATGCAAAGTGTGTATGTGTGTGTGTGTGTGTGTGTGTGTGTGT
TTGTGTGTATTTTGTAATATGTGAGGGAAATCTACCTTCGTTCATGTATAAATAAAGCTCCTCGTGGCTCCCTTTGTGACCAACCTGTTC
CTGCTCATCTCCTCCATCCTGGGGTCTCGCACCGCTGGCCCCCACACCCAGTTCGTGCAGTGGTTCATGGAGGAGTGTGTGGACTGCCTG
GAGCAGGGTGGCCGTGGCAGCGTCCTGCAGTTCATGCCCTTCACCACCCAGACCGATCCATGAGCAGCTCCCTCTCAGCCTCTCAGCTCC
ACACGGTCAACATGCGGGACCCTCTGAACCGAGTCCTGGGATTATATCAGCCTCTTCCCCCTGGACGATGTGCAGCCTTCGAAGTTGATG
CGACTGCTGAGCTCTAATGAGGACGATGCCAACATCCTTTCGAGCCCCAGCTGGCCGTGTGGTGTGCCCTCAGTTCCTACTCCTCCCACA
AGGGACAGGCGTCCACCCGCCAGAAGAAGAGACACCGCGAAGACATTGAGGAGCTGCTGAAGGAGACGCGGAAGGAGCACACGCTGCGGG
CAGTGGAGCTGCTCTACTCCATCTTCTGCCTGGACATGCAGCAAGTGACCCTGGTCCTGCTGGGCCACATCCTACCTGGCCTGCTCACTG
ACTCCTCCAAGTGGCACAGCCTCATGGACCCCCCGGGCACTGCTCTTGCCAAGGTGGTGATCATGAACTCGATCCTGGAGCGCATGTGTG
CCGACGTGCTGCAGCAGACAGCCACGCAGATCAAGTTTCCCTCCACCGGGGTGGACACAATGCCCTACTGGAACCTGCTGCCCCCCAAGC
GGCCCATCAAAGAGGTGCTGACGGACATTTTTGCCAAGGTGCTGGAGAAGGGCTGGGTGGACAGCCGCTCCATCCACATCTTTGACACCC
TGCTGCACATGGGCGGCGTCTACTGGTTCTGCAACAACCTGATTAAGAAAATCACTGATAACATCAAAGGGAAGGTATGCAGTCTGGCGG
TGTGTGCTGTGGCTTGGCTTGTGGCCCACGTCCGGATGCTGGGGCTGGATGAGCGTGAGAAGTCGCTGCAGATGATCCGCCAGCTGGCAG
GGCCACTGTTTAGTGAGAACACCCTGCAGTTCTACAATGAGAGGCAGATGAAGTGGCATGAGGCCTGTCTCAGCATCTCAGCCGCCATCT
TGGAAATCCTCAATGCCTGGGAGAATGGGGTCCTGGCCTTCGAGTCCATCCAGGTGATTCTGTCCGAGTCGCGCACAGGAGCTGAGGTGC
CCTTCTTCGAGACCTGGATGCAGACCTGCATGCCTGAGGAGGGCAAGATCCTGAACCCTGACCACCCCTGCTTCCGCCCCGACTCCACCA
AAGTGGAGTCCCTGGTGGCCCTGCTCAACAACTCCTCGGAGATGAAGCTAGTCCAAACCGGCCTCCGTCCGGGCCCTGCTGTTTGACATC
TCCTTCCTCATGCTGTGCCATGTGGCCCAGACCTATGGTTCAGAGTTTGAATGAATTCACAACCTATGGCAGCGAAGAAAGCAACGATGG
ATGCAGACCACTCTAAGTCACCGGAGGGACTGCTGGGAGTCCTGGGCCACATGCTGTCCGGGAAGAGTCTGGACTTGCTGCTGGCTGCCG
CCGCCGCCACTGGAAAGCTGAAATCCTTCGCCCGGAAATTCATCAACAAAGCGGACCGAGAGCACGCACCCCAGCAGAAATCGGGAGAGA
ATGCCAACATCCAGCCCAACATCCAGCTGATCCTCCGGGCGGAGCCCACTGTCACAAACATCCTCAAGCTGTGACTGTACAAACTTCCTG
CTCCAAGAATGTGGCAAGCAGGGGCTTCTGTCTGAGGCCAGCGTCAACAACCTTATGGCTAAGCGGACTTCACTGAGGATGTCAACTGTG
CTTTTGAGTTCCTGCTGAAGCTCACCCCCTTGTTGGACAAAGCTGACCAGCGCTGCAAATTCCACAGGTTTTGGTGAAGTTGAAGAAGTA
CTCTCATGGAGACAAGCATATCCCCACCCCACTTTTTGTCCTGGAGATCTGGAAAGCTTGCTTCGTGGGGCTCATTGAGTCTCCCGAGGG
TACGGAGGAGCTCAAGTGGACAGCTTTCACTTTCCTCAAGCATCCCCACGATGCTGTCTGTGCATGCGGAGCAGATGCACAAGACCGGCT
TCCCCACTGTCCACGCCGTGATCCTGCTCGAGGGCACCATGAACCTGACAGGCGAGACGCAGTCCCTGGTGGAGCAGCTGACGATGGTGA
AGCGCATGCAGCTTCTTGGACTGCCATCGAGCATTCTCTCTTGAAACTTGGAGAGATCCTGGCCAATCTCAGCAACCCGCAGCTCCGGAG
TCAGGCCGAGCAGTGTGGCACCCTCATTAGGAGCTGTCACGGCAAAGCAGAGGAATGCATCGGACTGTGCCGAGCCCTTCTTAGCGCCCT
CCACTGGCTGCTGCGCTGCACGGCAGCCTCTGCAGAGCGGCTGCGGGAGGGGCTGGAGGCCGGCACTCCAGCCGCTGGGGAGAAGCAGCT
TGCCATGTGCCTTCAGCGCCTGGAGAAAACCCTCAGCAGCACCAAGAACCGGGCCCTGCTGCACATCGCCAAACTAGAGGAGGCCTTTTG
ATGACTTTTCTCGGGACCTGTGTGTCCAGGCATTGCTGGACATCATGGACATGTTTTGTGACCGTCTGAGATGGTGTCCTACTCTTCTGT
CCTCACAGCCATCAGTAAGATGCGTTACTAGAGCAGGCCATGATTGGACCATCCCCCAATCCTCTCATCTTGTCCTACCTGAAGTATGCC
ATTAGTTCCCAGCTGGCCGCCACCGCTGCCACCTGCTCAGAGTGAAATAATGAAGGTGGTCAACCTGAAGCAAGCCATTTTGCAAGCCTG
GAAGGAGCGCTGGAGTGACTACCAATGGGCAATCAACATGAAGAAATTCTTTCCTAAAGGAGCCACCTGGGATATTCTCAACCTGGCAG

>1164_1164_1_ACACA-MED24_ACACA_chr17_35766352_ENST00000353139_MED24_chr17_38209888_ENST00000394126_length(amino acids)=341AA_BP=
MAVWCALSSYSSHKGQASTRQKKRHREDIEELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALA
KVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKK
ITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYNERQMKWHEACLSISAAILEILNAWENGVLAFESI
QVILSESRTGAEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQTGLRPGPAV

--------------------------------------------------------------
>1164_1164_2_ACACA-MED24_ACACA_chr17_35766352_ENST00000353139_MED24_chr17_38209910_ENST00000394126_length(transcript)=3981nt_BP=520nt
GCCCTCTTGGCCTTTTCCCGGTCCCCGCCGCGCGCCTGCTGCTGTCCCCGTGCCCGAGGACTGGGAGGATGGGGCTGAGCCGCTTGCCTG
ACTTTTGATCCGACCAGTAATCACTTTGCCCGTGTGGCGCGTGGCCCGTTGCCTGAGGCTTCCTGGCGCGTGGGGCTGTTTGGTCCCCTC
CGGAGTGCGGTGAGGCGGGCCGAGCCGGGACTGCCTGGGTTTGGGGATAACGTTCCCATCTCCACCCCTGTTGCAGCAAGGGAAATTGAG
GCTGAGGGAACTGGGCCCAGGGACGGCGAGCCGTGGCTGCCTCTCCAGTCCGGGCCCCGAAGGGCTGCTCGTGGATGAACCAGACTGATT
TTAAGGGGTGAAGAGGGTGCGTTTCAATCAGATGCTTCTGGAACGTCGAAATTGTCTTCTTTGGAAAGAACCATCCCCTCTTTGGGCTTC
AGAGGCCCAAATTGAGGCGCAATGATGAGAGGATGTGGTGGTCTACTCTGATGTCAATCTTGAGGGCTAGGTGTCGGAACTGGTGAAGGT
GTCAGCCATGTCCAGCCCCAAGGTGGTTCTGGCCATCACGGACCTCAGCCTGCCCCTGGGCCGCCAGGTGGCTGCTAAAGCCATTGCTGC
ACTCTGAGGGGCTTGGCATGGCCGCAGTGGGGGCTGGGGACTGGCGCAGCCCCAGGCGCCTCCAAGGGAAGCAGTGAGGAAAGATGAGGC
ATCGTGCCTCACATCCGCTCCACATGGTGCAAGAGCCTCTAGCGGCTTCCAGTTCCCCGCTCCTGACTCCTGACCTCCAGGATGTCTCCC
GGTTTCTTCTTTCAAAATTTCCTCTCCATCTGCTGGCACCTGAGGAGAGTGAGCAGCCTGGACCACAAGCCCAGTGGTCACCCCTGTGTG
CGCCCGCCCCAGCCCAGGAGTAGTCTTACCTCTGAGGAACTTTCTAGATGCAAAGTGTGTATGTGTGTGTGTGTGTGTGTGTGTGTGTGT
TTGTGTGTATTTTGTAATATGTGAGGGAAATCTACCTTCGTTCATGTATAAATAAAGCTCCTCGTGGCTCCCTTTGTGACCAACCTGTTC
CTGCTCATCTCCTCCATCCTGGGGTCTCGCACCGCTGGCCCCCACACCCAGTTCGTGCAGTGGTTCATGGAGGAGTGTGTGGACTGCCTG
GAGCAGGGTGGCCGTGGCAGCGTCCTGCAGTTCATGCCCTTCACCACCCAGACCGATCCATGAGCAGCTCCCTCTCAGCCTCTCAGCTCC
ACACGGTCAACATGCGGGACCCTCTGAACCGAGTCCTGGGATTATATCAGCCTCTTCCCCCTGGACGATGTGCAGCCTTCGAAGTTGATG
CGACTGCTGAGCTCTAATGAGGACGATGCCAACATCCTTTCGAGCCCCAGCTGGCCGTGTGGTGTGCCCTCAGTTCCTACTCCTCCCACA
AGGGACAGGCGTCCACCCGCCAGAAGAAGAGACACCGCGAAGACATTGAGGAGCTGCTGAAGGAGACGCGGAAGGAGCACACGCTGCGGG
CAGTGGAGCTGCTCTACTCCATCTTCTGCCTGGACATGCAGCAAGTGACCCTGGTCCTGCTGGGCCACATCCTACCTGGCCTGCTCACTG
ACTCCTCCAAGTGGCACAGCCTCATGGACCCCCCGGGCACTGCTCTTGCCAAGGTGGTGATCATGAACTCGATCCTGGAGCGCATGTGTG
CCGACGTGCTGCAGCAGACAGCCACGCAGATCAAGTTTCCCTCCACCGGGGTGGACACAATGCCCTACTGGAACCTGCTGCCCCCCAAGC
GGCCCATCAAAGAGGTGCTGACGGACATTTTTGCCAAGGTGCTGGAGAAGGGCTGGGTGGACAGCCGCTCCATCCACATCTTTGACACCC
TGCTGCACATGGGCGGCGTCTACTGGTTCTGCAACAACCTGATTAAGAAAATCACTGATAACATCAAAGGGAAGGTATGCAGTCTGGCGG
TGTGTGCTGTGGCTTGGCTTGTGGCCCACGTCCGGATGCTGGGGCTGGATGAGCGTGAGAAGTCGCTGCAGATGATCCGCCAGCTGGCAG
GGCCACTGTTTAGTGAGAACACCCTGCAGTTCTACAATGAGAGGCAGATGAAGTGGCATGAGGCCTGTCTCAGCATCTCAGCCGCCATCT
TGGAAATCCTCAATGCCTGGGAGAATGGGGTCCTGGCCTTCGAGTCCATCCAGGTGATTCTGTCCGAGTCGCGCACAGGAGCTGAGGTGC
CCTTCTTCGAGACCTGGATGCAGACCTGCATGCCTGAGGAGGGCAAGATCCTGAACCCTGACCACCCCTGCTTCCGCCCCGACTCCACCA
AAGTGGAGTCCCTGGTGGCCCTGCTCAACAACTCCTCGGAGATGAAGCTAGTCCAAACCGGCCTCCGTCCGGGCCCTGCTGTTTGACATC
TCCTTCCTCATGCTGTGCCATGTGGCCCAGACCTATGGTTCAGAGTTTGAATGAATTCACAACCTATGGCAGCGAAGAAAGCAACGATGG
ATGCAGACCACTCTAAGTCACCGGAGGGACTGCTGGGAGTCCTGGGCCACATGCTGTCCGGGAAGAGTCTGGACTTGCTGCTGGCTGCCG
CCGCCGCCACTGGAAAGCTGAAATCCTTCGCCCGGAAATTCATCAACAAAGCGGACCGAGAGCACGCACCCCAGCAGAAATCGGGAGAGA
ATGCCAACATCCAGCCCAACATCCAGCTGATCCTCCGGGCGGAGCCCACTGTCACAAACATCCTCAAGCTGTGACTGTACAAACTTCCTG
CTCCAAGAATGTGGCAAGCAGGGGCTTCTGTCTGAGGCCAGCGTCAACAACCTTATGGCTAAGCGGACTTCACTGAGGATGTCAACTGTG
CTTTTGAGTTCCTGCTGAAGCTCACCCCCTTGTTGGACAAAGCTGACCAGCGCTGCAAATTCCACAGGTTTTGGTGAAGTTGAAGAAGTA
CTCTCATGGAGACAAGCATATCCCCACCCCACTTTTTGTCCTGGAGATCTGGAAAGCTTGCTTCGTGGGGCTCATTGAGTCTCCCGAGGG
TACGGAGGAGCTCAAGTGGACAGCTTTCACTTTCCTCAAGCATCCCCACGATGCTGTCTGTGCATGCGGAGCAGATGCACAAGACCGGCT
TCCCCACTGTCCACGCCGTGATCCTGCTCGAGGGCACCATGAACCTGACAGGCGAGACGCAGTCCCTGGTGGAGCAGCTGACGATGGTGA
AGCGCATGCAGCTTCTTGGACTGCCATCGAGCATTCTCTCTTGAAACTTGGAGAGATCCTGGCCAATCTCAGCAACCCGCAGCTCCGGAG
TCAGGCCGAGCAGTGTGGCACCCTCATTAGGAGCTGTCACGGCAAAGCAGAGGAATGCATCGGACTGTGCCGAGCCCTTCTTAGCGCCCT
CCACTGGCTGCTGCGCTGCACGGCAGCCTCTGCAGAGCGGCTGCGGGAGGGGCTGGAGGCCGGCACTCCAGCCGCTGGGGAGAAGCAGCT
TGCCATGTGCCTTCAGCGCCTGGAGAAAACCCTCAGCAGCACCAAGAACCGGGCCCTGCTGCACATCGCCAAACTAGAGGAGGCCTTTTG
ATGACTTTTCTCGGGACCTGTGTGTCCAGGCATTGCTGGACATCATGGACATGTTTTGTGACCGTCTGAGATGGTGTCCTACTCTTCTGT
CCTCACAGCCATCAGTAAGATGCGTTACTAGAGCAGGCCATGATTGGACCATCCCCCAATCCTCTCATCTTGTCCTACCTGAAGTATGCC
ATTAGTTCCCAGCTCCATTTCTTTCACCTCAAAGCTGGCCGCCACCGCTGCCACCTGCTCAGAGTGAAATAATGAAGGTGGTCAACCTGA
AGCAAGCCATTTTGCAAGCCTGGAAGGAGCGCTGGAGTGACTACCAATGGGCAATCAACATGAAGAAATTCTTTCCTAAAGGAGCCACCT
GGGATATTCTCAACCTGGCAG

>1164_1164_2_ACACA-MED24_ACACA_chr17_35766352_ENST00000353139_MED24_chr17_38209910_ENST00000394126_length(amino acids)=341AA_BP=
MAVWCALSSYSSHKGQASTRQKKRHREDIEELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALA
KVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKK
ITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYNERQMKWHEACLSISAAILEILNAWENGVLAFESI
QVILSESRTGAEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQTGLRPGPAV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ACACA-MED24


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ACACA-MED24


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ACACA-MED24


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneACACAC0018801Heart failure1CTD_human
HgeneACACAC0018802Congestive heart failure1CTD_human
HgeneACACAC0023212Left-Sided Heart Failure1CTD_human
HgeneACACAC0235527Heart Failure, Right-Sided1CTD_human
HgeneACACAC1959583Myocardial Failure1CTD_human
HgeneACACAC1961112Heart Decompensation1CTD_human
HgeneACACAC2239176Liver carcinoma1CTD_human