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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:APBA2-SNHG14 (FusionGDB2 ID:HG321TG104472715)

Fusion Gene Summary for APBA2-SNHG14

check button Fusion gene summary
Fusion gene informationFusion gene name: APBA2-SNHG14
Fusion gene ID: hg321tg104472715
HgeneTgene
Gene symbol

APBA2

SNHG14

Gene ID

321

104472715

Gene nameamyloid beta precursor protein binding family A member 2small nucleolar RNA host gene 14
SynonymsD15S1518E|HsT16821|LIN-10|MGC:14091|MINT2|X11-BETA|X11L115HG|IC-SNURF-SNRPN|LNCAT|NCRNA00214|U-UBE3A-ATS|UBE3A-AS|UBE3A-AS1|UBE3A-ATS|UBE3AATS
Cytomap('APBA2')('SNHG14')

15q13.1

15q11.2

Type of geneprotein-codingncRNA
Descriptionamyloid-beta A4 precursor protein-binding family A member 2X11-like proteinadapter protein X11betaamyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)mint-2neuron-specific X11L proteinneuronal munc18-1-interacting protein 2phoUBE3A antisense RNA 1 (non-protein coding)UBE3A antisense transcriptlarge noncoding antisense transcriptsmall nucleolar RNA host gene 14 (non-protein coding)
Modification date2020031320200303
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000411764, ENST00000558259, 
ENST00000558330, ENST00000558402, 
ENST00000561069, 
Fusion gene scores* DoF score12 X 7 X 8=67216 X 19 X 4=1216
# samples 1220
** MAII scorelog2(12/672*10)=-2.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(20/1216*10)=-2.60407132366886
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: APBA2 [Title/Abstract] AND SNHG14 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAPBA2(29288009)-SNHG14(25336737), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID


check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-A4PD-01AAPBA2chr15

29288009

+SNHG14chr15

25336737

+


Top

Fusion Gene ORF analysis for APBA2-SNHG14

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3UTRENST00000411764ENST00000546682APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-3UTRENST00000411764ENST00000549804APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-3UTRENST00000411764ENST00000553108APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-3UTRENST00000558259ENST00000546682APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-3UTRENST00000558259ENST00000549804APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-3UTRENST00000558259ENST00000553108APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-3UTRENST00000558330ENST00000546682APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-3UTRENST00000558330ENST00000549804APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-3UTRENST00000558330ENST00000553108APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-3UTRENST00000558402ENST00000546682APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-3UTRENST00000558402ENST00000549804APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-3UTRENST00000558402ENST00000553108APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-3UTRENST00000561069ENST00000546682APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-3UTRENST00000561069ENST00000549804APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-3UTRENST00000561069ENST00000553108APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000363358APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000365067APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000365306APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000384430APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000384733APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000390982APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000414175APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000424208APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000424333APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000441592APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000450809APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000452731APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000453082APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000456576APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000459433APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000516123APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000547292APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000551077APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000551361APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000551631APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000551938APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000553134APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000553149APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000554726APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000411764ENST00000580438APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000363358APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000365067APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000365306APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000384430APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000384733APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000390982APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000414175APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000424208APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000424333APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000441592APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000450809APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000452731APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000453082APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000456576APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000459433APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000516123APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000547292APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000551077APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000551361APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000551631APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000551938APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000553134APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000553149APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000554726APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558259ENST00000580438APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000363358APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000365067APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000365306APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000384430APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000384733APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000390982APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000414175APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000424208APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000424333APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000441592APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000450809APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000452731APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000453082APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000456576APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000459433APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000516123APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000547292APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000551077APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000551361APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000551631APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000551938APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000553134APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000553149APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000554726APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558330ENST00000580438APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000363358APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000365067APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000365306APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000384430APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000384733APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000390982APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000414175APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000424208APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000424333APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000441592APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000450809APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000452731APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000453082APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000456576APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000459433APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000516123APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000547292APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000551077APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000551361APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000551631APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000551938APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000553134APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000553149APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000554726APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000558402ENST00000580438APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000363358APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000365067APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000365306APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000384430APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000384733APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000390982APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000414175APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000424208APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000424333APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000441592APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000450809APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000452731APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000453082APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000456576APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000459433APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000516123APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000547292APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000551077APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000551361APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000551631APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000551938APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000553134APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000553149APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000554726APBA2chr15

29288009

+SNHG14chr15

25336737

+
5UTR-intronENST00000561069ENST00000580438APBA2chr15

29288009

+SNHG14chr15

25336737

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

Top

Fusion Genomic Features for APBA2-SNHG14


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
APBA2chr1529288009+SNHG14chr1525336736+0.0027493940.9972506
APBA2chr1529288009+SNHG14chr1525336736+0.0027493940.9972506


check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for APBA2-SNHG14


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:29288009/:25336737)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for APBA2-SNHG14


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for APBA2-SNHG14


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for APBA2-SNHG14


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for APBA2-SNHG14


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneAPBA2C0036341Schizophrenia1PSYGENET
HgeneAPBA2C0037274Dermatologic disorders1CTD_human