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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:IGF1R-ARID1B (FusionGDB2 ID:HG3480TG57492)

Fusion Gene Summary for IGF1R-ARID1B

check button Fusion gene summary
Fusion gene informationFusion gene name: IGF1R-ARID1B
Fusion gene ID: hg3480tg57492
HgeneTgene
Gene symbol

IGF1R

ARID1B

Gene ID

3480

57492

Gene nameinsulin like growth factor 1 receptorAT-rich interaction domain 1B
SynonymsCD221|IGFIR|IGFR|JTK136A3-5|BAF250B|BRIGHT|CSS1|DAN15|ELD/OSA1|MRD12|OSA2|P250R
Cytomap('IGF1R')('ARID1B')

15q26.3

6q25.3

Type of geneprotein-codingprotein-coding
Descriptioninsulin-like growth factor 1 receptorIGF-I receptorsoluble IGF1R variant 1soluble IGF1R variant 2AT-rich interactive domain-containing protein 1BARID domain-containing protein 1BAT rich interactive domain 1B (SWI1-like)BRG1-associated factor 250bBRG1-binding protein ELD/OSA1ELD (eyelid)/OSA protein
Modification date2020032920200320
UniProtAcc

P08069

.
Ensembl transtripts involved in fusion geneENST00000268035, ENST00000558762, 
ENST00000560432, 
Fusion gene scores* DoF score24 X 15 X 6=216010 X 12 X 6=720
# samples 2512
** MAII scorelog2(25/2160*10)=-3.11103131238874
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/720*10)=-2.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: IGF1R [Title/Abstract] AND ARID1B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointIGF1R(99251336)-ARID1B(157469758), # samples:3
Anticipated loss of major functional domain due to fusion event.IGF1R-ARID1B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
IGF1R-ARID1B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
IGF1R-ARID1B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
IGF1R-ARID1B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneIGF1R

GO:0043066

negative regulation of apoptotic process

12556535

HgeneIGF1R

GO:0046328

regulation of JNK cascade

12556535

HgeneIGF1R

GO:0046777

protein autophosphorylation

1846292|7679099|11162456

HgeneIGF1R

GO:0048009

insulin-like growth factor receptor signaling pathway

7679099

HgeneIGF1R

GO:0048015

phosphatidylinositol-mediated signaling

7692086

HgeneIGF1R

GO:0051389

inactivation of MAPKK activity

12556535


check buttonFusion gene breakpoints across IGF1R (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ARID1B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E9-A1NF-01AIGF1Rchr15

99251336

-ARID1Bchr6

157469758

+
ChimerDB4BRCATCGA-E9-A1NF-01AIGF1Rchr15

99251336

+ARID1Bchr6

157469758

+


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Fusion Gene ORF analysis for IGF1R-ARID1B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000268035ENST00000478761IGF1Rchr15

99251336

+ARID1Bchr6

157469758

+
5CDS-intronENST00000558762ENST00000478761IGF1Rchr15

99251336

+ARID1Bchr6

157469758

+
In-frameENST00000268035ENST00000275248IGF1Rchr15

99251336

+ARID1Bchr6

157469758

+
In-frameENST00000268035ENST00000346085IGF1Rchr15

99251336

+ARID1Bchr6

157469758

+
In-frameENST00000268035ENST00000350026IGF1Rchr15

99251336

+ARID1Bchr6

157469758

+
In-frameENST00000268035ENST00000367148IGF1Rchr15

99251336

+ARID1Bchr6

157469758

+
In-frameENST00000558762ENST00000275248IGF1Rchr15

99251336

+ARID1Bchr6

157469758

+
In-frameENST00000558762ENST00000346085IGF1Rchr15

99251336

+ARID1Bchr6

157469758

+
In-frameENST00000558762ENST00000350026IGF1Rchr15

99251336

+ARID1Bchr6

157469758

+
In-frameENST00000558762ENST00000367148IGF1Rchr15

99251336

+ARID1Bchr6

157469758

+
intron-3CDSENST00000560432ENST00000275248IGF1Rchr15

99251336

+ARID1Bchr6

157469758

+
intron-3CDSENST00000560432ENST00000346085IGF1Rchr15

99251336

+ARID1Bchr6

157469758

+
intron-3CDSENST00000560432ENST00000350026IGF1Rchr15

99251336

+ARID1Bchr6

157469758

+
intron-3CDSENST00000560432ENST00000367148IGF1Rchr15

99251336

+ARID1Bchr6

157469758

+
intron-intronENST00000560432ENST00000478761IGF1Rchr15

99251336

+ARID1Bchr6

157469758

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000268035IGF1Rchr1599251336+ENST00000350026ARID1Bchr6157469758+6709125161154491612
ENST00000268035IGF1Rchr1599251336+ENST00000346085ARID1Bchr6157469758+8338125161154491612
ENST00000268035IGF1Rchr1599251336+ENST00000367148ARID1Bchr6157469758+6985125161156081665
ENST00000268035IGF1Rchr1599251336+ENST00000275248ARID1Bchr6157469758+6985125161156081665
ENST00000558762IGF1Rchr1599251336+ENST00000350026ARID1Bchr6157469758+6636117853853761612
ENST00000558762IGF1Rchr1599251336+ENST00000346085ARID1Bchr6157469758+8265117853853761612
ENST00000558762IGF1Rchr1599251336+ENST00000367148ARID1Bchr6157469758+6912117853855351665
ENST00000558762IGF1Rchr1599251336+ENST00000275248ARID1Bchr6157469758+6912117853855351665

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000268035ENST00000350026IGF1Rchr1599251336+ARID1Bchr6157469758+0.0029610820.99703896
ENST00000268035ENST00000346085IGF1Rchr1599251336+ARID1Bchr6157469758+0.0010954240.9989046
ENST00000268035ENST00000367148IGF1Rchr1599251336+ARID1Bchr6157469758+0.0028196190.99718034
ENST00000268035ENST00000275248IGF1Rchr1599251336+ARID1Bchr6157469758+0.0028196190.99718034
ENST00000558762ENST00000350026IGF1Rchr1599251336+ARID1Bchr6157469758+0.0026916370.9973084
ENST00000558762ENST00000346085IGF1Rchr1599251336+ARID1Bchr6157469758+0.0010144890.99898547
ENST00000558762ENST00000367148IGF1Rchr1599251336+ARID1Bchr6157469758+0.0025529760.997447
ENST00000558762ENST00000275248IGF1Rchr1599251336+ARID1Bchr6157469758+0.0025529760.997447

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Fusion Genomic Features for IGF1R-ARID1B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
IGF1Rchr1599251336+ARID1Bchr6157469757+2.54E-060.9999975
IGF1Rchr1599251336+ARID1Bchr6157469757+2.54E-060.9999975

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for IGF1R-ARID1B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:99251336/chr6:157469758)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
IGF1R

P08069

.
FUNCTION: Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of multiple substrates, that function as signaling adapter proteins including, the insulin-receptor substrates (IRS1/2), Shc and 14-3-3 proteins. Phosphorylation of IRSs proteins lead to the activation of two main signaling pathways: the PI3K-AKT/PKB pathway and the Ras-MAPK pathway. The result of activating the MAPK pathway is increased cellular proliferation, whereas activating the PI3K pathway inhibits apoptosis and stimulates protein synthesis. Phosphorylated IRS1 can activate the 85 kDa regulatory subunit of PI3K (PIK3R1), leading to activation of several downstream substrates, including protein AKT/PKB. AKT phosphorylation, in turn, enhances protein synthesis through mTOR activation and triggers the antiapoptotic effects of IGFIR through phosphorylation and inactivation of BAD. In parallel to PI3K-driven signaling, recruitment of Grb2/SOS by phosphorylated IRS1 or Shc leads to recruitment of Ras and activation of the ras-MAPK pathway. In addition to these two main signaling pathways IGF1R signals also through the Janus kinase/signal transducer and activator of transcription pathway (JAK/STAT). Phosphorylation of JAK proteins can lead to phosphorylation/activation of signal transducers and activators of transcription (STAT) proteins. In particular activation of STAT3, may be essential for the transforming activity of IGF1R. The JAK/STAT pathway activates gene transcription and may be responsible for the transforming activity. JNK kinases can also be activated by the IGF1R. IGF1 exerts inhibiting activities on JNK activation via phosphorylation and inhibition of MAP3K5/ASK1, which is able to directly associate with the IGF1R.; FUNCTION: When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneARID1Bchr15:99251336chr6:157469758ENST000003460857201034_10378502250.0Compositional biasNote=Poly-Ser
TgeneARID1Bchr15:99251336chr6:157469758ENST000003460857201441_14448502250.0Compositional biasNote=Poly-Ser
TgeneARID1Bchr15:99251336chr6:157469758ENST000003460857201459_15978502250.0Compositional biasNote=Pro-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST000003460857201833_18368502250.0Compositional biasNote=Poly-Pro
TgeneARID1Bchr15:99251336chr6:157469758ENST00000346085720932_9358502250.0Compositional biasNote=Poly-Ala
TgeneARID1Bchr15:99251336chr6:157469758ENST000003500266191034_10378372237.0Compositional biasNote=Poly-Ser
TgeneARID1Bchr15:99251336chr6:157469758ENST000003500266191441_14448372237.0Compositional biasNote=Poly-Ser
TgeneARID1Bchr15:99251336chr6:157469758ENST000003500266191459_15978372237.0Compositional biasNote=Pro-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST000003500266191833_18368372237.0Compositional biasNote=Poly-Pro
TgeneARID1Bchr15:99251336chr6:157469758ENST00000350026619932_9358372237.0Compositional biasNote=Poly-Ala
TgeneARID1Bchr15:99251336chr6:157469758ENST000003671486201034_10378372290.0Compositional biasNote=Poly-Ser
TgeneARID1Bchr15:99251336chr6:157469758ENST000003671486201441_14448372290.0Compositional biasNote=Poly-Ser
TgeneARID1Bchr15:99251336chr6:157469758ENST000003671486201459_15978372290.0Compositional biasNote=Pro-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST000003671486201833_18368372290.0Compositional biasNote=Poly-Pro
TgeneARID1Bchr15:99251336chr6:157469758ENST00000367148620932_9358372290.0Compositional biasNote=Poly-Ala
TgeneARID1Bchr15:99251336chr6:157469758ENST000003460857201053_11448502250.0DomainARID
TgeneARID1Bchr15:99251336chr6:157469758ENST000003500266191053_11448372237.0DomainARID
TgeneARID1Bchr15:99251336chr6:157469758ENST000003671486201053_11448372290.0DomainARID
TgeneARID1Bchr15:99251336chr6:157469758ENST000003460857201358_13778502250.0MotifNuclear localization signal
TgeneARID1Bchr15:99251336chr6:157469758ENST000003460857202036_20408502250.0MotifNote=LXXLL
TgeneARID1Bchr15:99251336chr6:157469758ENST000003500266191358_13778372237.0MotifNuclear localization signal
TgeneARID1Bchr15:99251336chr6:157469758ENST000003500266192036_20408372237.0MotifNote=LXXLL
TgeneARID1Bchr15:99251336chr6:157469758ENST000003671486201358_13778372290.0MotifNuclear localization signal
TgeneARID1Bchr15:99251336chr6:157469758ENST000003671486202036_20408372290.0MotifNote=LXXLL

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneIGF1Rchr15:99251336chr6:157469758ENST00000268035+221491_6092131368.0DomainFibronectin type-III 1
HgeneIGF1Rchr15:99251336chr6:157469758ENST00000268035+221610_7082131368.0DomainFibronectin type-III 2
HgeneIGF1Rchr15:99251336chr6:157469758ENST00000268035+221735_8282131368.0DomainFibronectin type-III 3
HgeneIGF1Rchr15:99251336chr6:157469758ENST00000268035+221834_9272131368.0DomainFibronectin type-III 4
HgeneIGF1Rchr15:99251336chr6:157469758ENST00000268035+221999_12742131368.0DomainProtein kinase
HgeneIGF1Rchr15:99251336chr6:157469758ENST00000268035+221977_9802131368.0MotifNote=IRS1- and SHC1-binding
HgeneIGF1Rchr15:99251336chr6:157469758ENST00000268035+2211005_10132131368.0Nucleotide bindingATP
HgeneIGF1Rchr15:99251336chr6:157469758ENST00000268035+221741_9352131368.0Topological domainExtracellular
HgeneIGF1Rchr15:99251336chr6:157469758ENST00000268035+221960_13672131368.0Topological domainCytoplasmic
HgeneIGF1Rchr15:99251336chr6:157469758ENST00000268035+221936_9592131368.0TransmembraneHelical
TgeneARID1Bchr15:99251336chr6:157469758ENST00000346085720107_1318502250.0Compositional biasNote=Gln-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST00000346085720114_1318502250.0Compositional biasNote=Poly-Gln
TgeneARID1Bchr15:99251336chr6:157469758ENST00000346085720141_4018502250.0Compositional biasNote=Gly-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST000003460857202_478502250.0Compositional biasNote=Ala-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST00000346085720329_4938502250.0Compositional biasNote=Ala-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST0000034608572035_578502250.0Compositional biasNote=Ser-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST00000346085720574_6338502250.0Compositional biasNote=Gln-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST00000346085720684_7718502250.0Compositional biasNote=Ser-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST0000034608572081_1048502250.0Compositional biasNote=His-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST00000350026619107_1318372237.0Compositional biasNote=Gln-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST00000350026619114_1318372237.0Compositional biasNote=Poly-Gln
TgeneARID1Bchr15:99251336chr6:157469758ENST00000350026619141_4018372237.0Compositional biasNote=Gly-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST000003500266192_478372237.0Compositional biasNote=Ala-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST00000350026619329_4938372237.0Compositional biasNote=Ala-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST0000035002661935_578372237.0Compositional biasNote=Ser-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST00000350026619574_6338372237.0Compositional biasNote=Gln-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST00000350026619684_7718372237.0Compositional biasNote=Ser-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST0000035002661981_1048372237.0Compositional biasNote=His-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST00000367148620107_1318372290.0Compositional biasNote=Gln-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST00000367148620114_1318372290.0Compositional biasNote=Poly-Gln
TgeneARID1Bchr15:99251336chr6:157469758ENST00000367148620141_4018372290.0Compositional biasNote=Gly-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST000003671486202_478372290.0Compositional biasNote=Ala-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST00000367148620329_4938372290.0Compositional biasNote=Ala-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST0000036714862035_578372290.0Compositional biasNote=Ser-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST00000367148620574_6338372290.0Compositional biasNote=Gln-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST00000367148620684_7718372290.0Compositional biasNote=Ser-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST0000036714862081_1048372290.0Compositional biasNote=His-rich
TgeneARID1Bchr15:99251336chr6:157469758ENST00000346085720419_4238502250.0MotifNote=LXXLL
TgeneARID1Bchr15:99251336chr6:157469758ENST00000350026619419_4238372237.0MotifNote=LXXLL
TgeneARID1Bchr15:99251336chr6:157469758ENST00000367148620419_4238372290.0MotifNote=LXXLL


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Fusion Gene Sequence for IGF1R-ARID1B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>38471_38471_1_IGF1R-ARID1B_IGF1R_chr15_99251336_ENST00000268035_ARID1B_chr6_157469758_ENST00000275248_length(transcript)=6985nt_BP=1251nt
GGGAAGGAGCTCGCCGCGGCGGCGGCGGCGCTGAGGGAGGAGGCGGCGGCGAGCGGAGCCAGGAGGAGGAGGAGGAGGGGGAGCCGCTCA
TTCATTTTGACTCCGCGTTTCTGCCCCTCGCCGGCCTCGCCTGTGACCCGGACTTCGGGGCGATCTTGCGAACTGCGTCGCGCCCTCCCG
CGGCGGAAGCTCGGGCGTCCGGCCGCCTCCCGCGCGGCCAGGGCCGGGCTTGTTTTTCCTCGCCTAGGCAGATTTGGGCTTTGCCCCCTT
TCTTTGCAGTTTTCCCCCCTTCCTGCCTCTCCGGGTTTGAAAATGGAGGCCGACGACGCCGACAGCCCGCCCCGGCGCGCCTCGGGTTCC
CGACTCCGCCGAGCCCTGGGCCGCTGCTGCCGGCGCTGAGGGGCCGCCCCGCGCCGCCCGCCCCGTCCGCGCACCCGGAGGGCCCCGGCG
GCGCCGCCTTCGGAGTATTGTTTCCTTCGCCCTTGTTTTTGGAGGGGGAGCGAAGACTGAGTTTGAGACTTGTTTCCTTTCATTTCCTTT
TTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGAAAGGGGAATTTCATCCCAAATAAAAGGAATGAAGTCTGGCTCCGGAG
GAGGGTCCCCGACCTCGCTGTGGGGGCTCCTGTTTCTCTCCGCCGCGCTCTCGCTCTGGCCGACGAGTGGAGAAATCTGCGGGCCAGGCA
TCGACATCCGCAACGACTATCAGCAGCTGAAGCGCCTGGAGAACTGCACGGTGATCGAGGGCTACCTCCACATCCTGCTCATCTCCAAGG
CCGAGGACTACCGCAGCTACCGCTTCCCCAAGCTCACGGTCATTACCGAGTACTTGCTGCTGTTCCGAGTGGCTGGCCTCGAGAGCCTCG
GAGACCTCTTCCCCAACCTCACGGTCATCCGCGGCTGGAAACTCTTCTACAACTACGCCCTGGTCATCTTCGAGATGACCAATCTCAAGG
ATATTGGGCTTTACAACCTGAGGAACATTACTCGGGGGGCCATCAGGATTGAGAAAAATGCTGACCTCTGTTACCTCTCCACTGTGGACT
GGTCCCTGATCCTGGATGCGGTGTCCAATAACTACATTGTGGGGAATAAGCCCCCAAAGGAATGTGGGGACCTGTGTCCAGGGACCATGG
AGGAGAAGCCGATGTGTGAGAAGACCACCATCAACAATGAGTACAACTACCGCTGCTGGACCACAAACCGCTGCCAGAAAAGTAACTACT
CCAGACCCCCAGCGTATAGTGGGGTGCCCAGTGCAAGCTACAGCGGCCCAGGGCCCGGTATGGGTATCAGTGCCAACAACCAGATGCATG
GACAAGGGCCAAGCCAGCCATGTGGTGCTGTGCCCCTGGGACGAATGCCATCAGCTGGGATGCAGAACAGACCATTTCCTGGAAATATGA
GCAGCATGACCCCCAGTTCTCCTGGCATGTCTCAGCAGGGAGGGCCAGGAATGGGGCCGCCAATGCCAACTGTGAACCGTAAGGCACAGG
AGGCAGCCGCAGCAGTGATGCAGGCTGCTGCGAACTCAGCACAAAGCAGGCAAGGCAGTTTCCCCGGCATGAACCAGAGTGGACTTATGG
CTTCCAGCTCTCCCTACAGCCAGCCCATGAACAACAGCTCTAGCCTGATGAACACGCAGGCGCCGCCCTACAGCATGGCGCCCGCCATGG
TGAACAGCTCGGCAGCATCTGTGGGTCTTGCAGATATGATGTCTCCTGGTGAATCCAAACTGCCCCTGCCTCTCAAAGCAGACGGCAAAG
AAGAAGGCACTCCACAGCCCGAGAGCAAGTCAAAGGATAGCTACAGCTCTCAGGGTATTTCTCAGCCCCCAACCCCAGGCAACCTGCCAG
TCCCTTCCCCAATGTCCCCCAGCTCTGCTAGCATCTCCTCATTTCATGGAGATGAAAGTGATAGCATTAGCAGCCCAGGCTGGCCAAAGA
CTCCATCAAGCCCTAAGTCCAGCTCCTCCACCACTACTGGGGAGAAGATCACGAAGGTGTACGAGCTGGGGAATGAGCCAGAGAGAAAGC
TCTGGGTCGACCGATACCTCACCTTCATGGAAGAGAGAGGCTCTCCTGTCTCAAGTCTGCCTGCCGTGGGCAAGAAGCCCCTGGACCTGT
TCCGACTCTACGTCTGCGTCAAAGAGATCGGGGGTTTGGCCCAGGTTAATAAAAACAAGAAGTGGCGTGAGCTGGCAACCAACCTAAACG
TTGGCACCTCAAGCAGTGCAGCGAGCTCCCTGAAAAAGCAGTATATTCAGTACCTGTTTGCCTTTGAGTGCAAGATCGAACGTGGGGAGG
AGCCCCCGCCGGAAGTCTTCAGCACCGGGGACACCAAAAAGCAGCCCAAGCTCCAGCCGCCATCTCCTGCTAACTCGGGATCCTTGCAAG
GCCCACAGACCCCCCAGTCAACTGGCAGCAATTCCATGGCAGAGGTTCCAGGTGACCTGAAGCCACCTACCCCAGCCTCCACCCCTCACG
GCCAGATGACTCCAATGCAAGGTGGAAGAAGCAGTACAATCAGTGTGCACGACCCATTCTCAGATGTGAGTGATTCATCCTTCCCGAAAC
GGAACTCCATGACTCCAAACGCCCCCTACCAGCAGGGCATGAGCATGCCCGATGTGATGGGCAGGATGCCCTATGAGCCCAACAAGGACC
CCTTTGGGGGAATGAGAAAAGTGCCTGGAAGCAGCGAGCCCTTTATGACGCAAGGACAGATGCCCAACAGCAGCATGCAGGACATGTACA
ACCAAAGTCCCTCCGGAGCAATGTCTAACCTGGGCATGGGGCAGCGCCAGCAGTTTCCCTATGGAGCCAGTTACGACCGAAGGCATGAAC
CTTATGGGCAGCAGTATCCAGGCCAAGGCCCTCCCTCGGGACAGCCGCCGTATGGAGGGCACCAGCCCGGCCTGTACCCACAGCAGCCGA
ATTACAAACGCCATATGGACGGCATGTACGGGCCCCCAGCCAAGCGCCACGAGGGCGACATGTACAACATGCAGTACAGCAGCCAGCAGC
AGGAGATGTACAACCAGTATGGAGGCTCCTACTCGGGCCCGGACCGCAGGCCCATCCAGGGCCAGTACCCGTATCCCTACAGCAGGGAGA
GGATGCAGGGCCCGGGGCAGATCCAGACACACGGAATCCCGCCTCAGATGATGGGCGGCCCGCTGCAGTCGTCCTCCAGTGAGGGGCCTC
AGCAGAATATGTGGGCAGCACGCAATGATATGCCTTATCCCTACCAGAACAGGCAGGGCCCTGGCGGCCCTACACAGGCGCCCCCTTACC
CAGGCATGAACCGCACAGACGATATGATGGTACCCGATCAGAGGATAAATCATGAGAGCCAGTGGCCTTCTCACGTCAGCCAGCGTCAGC
CTTATATGTCGTCCTCAGCCTCCATGCAGCCCATCACACGCCCACCACAGCCGTCCTACCAGACGCCACCGTCACTGCCAAATCACATCT
CCAGGGCGCCCAGCCCAGCGTCCTTCCAGCGCTCCCTGGAGAACCGCATGTCTCCAAGCAAGTCTCCTTTTCTGCCGTCTATGAAGATGC
AGAAGGTCATGCCCACGGTCCCCACATCCCAGGTCACCGGGCCACCACCCCAACCACCCCCAATCAGAAGGGAGATCACCTTTCCTCCTG
GCTCAGTAGAAGCATCACAACCAGTCTTGAAACAAAGGCGAAAGATTACCTCCAAAGATATCGTTACTCCTGAGGCGTGGCGTGTGATGA
TGTCCCTTAAATCAGGTCTTTTGGCTGAGAGTACGTGGGCTTTGGACACTATTAATATTCTTCTGTATGATGACAGCACTGTTGCTACTT
TCAATCTCTCCCAGTTGTCTGGATTTCTCGAACTTTTAGTCGAGTACTTTAGAAAATGCCTGATTGACATTTTTGGAATTCTTATGGAAT
ATGAAGTGGGAGACCCCAGCCAAAAAGCACTTGATCACAACGCAGCAAGGAAGGATGACAGCCAGTCCTTGGCAGACGATTCTGGGAAAG
AGGAGGAAGATGCTGAATGTATTGATGACGACGAGGAAGACGAGGAGGATGAGGAGGAAGACAGCGAGAAGACAGAAAGCGATGAAAAGA
GCAGCATCGCTCTGACTGCCCCGGACGCCGCTGCAGACCCAAAGGAGAAGCCCAAGCAAGCCAGTAAGTTCGACAAGCTGCCAATAAAGA
TAGTCAAAAAGAACAACCTGTTTGTTGTTGACCGATCTGACAAGTTGGGGCGTGTGCAGGAGTTCAATAGTGGCCTTCTGCACTGGCAGC
TCGGCGGGGGTGACACCACCGAGCACATTCAGACTCACTTTGAGAGCAAGATGGAAATTCCTCCTCGCAGGCGCCCACCTCCCCCCTTAA
GCTCCGCAGGTAGAAAGAAAGAGCAAGAAGGCAAAGGCGACTCTGAAGAGCAGCAAGAGAAAAGCATCATAGCAACCATCGATGACGTCC
TCTCTGCTCGGCCAGGGGCATTGCCTGAAGACGCAAACCCTGGGCCCCAGACCGAAAGCAGTAAGTTTCCCTTTGGTATCCAGCAAGCCA
AAAGTCACCGGAACATCAAGCTGCTGGAGGACGAGCCCAGGAGCCGAGACGAGACTCCTCTGTGTACCATCGCGCACTGGCAGGACTCGC
TGGCTAAGCGATGCATCTGTGTGTCCAATATTGTCCGTAGCTTGTCATTCGTGCCTGGCAATGATGCCGAAATGTCCAAACATCCAGGCC
TGGTGCTGATCCTGGGGAAGCTGATTCTTCTTCACCACGAGCATCCAGAGAGAAAGCGAGCACCGCAGACCTATGAGAAAGAGGAGGATG
AGGACAAGGGGGTGGCCTGCAGCAAAGATGAGTGGTGGTGGGACTGCCTCGAGGTCTTGAGGGATAACACGTTGGTCACGTTGGCCAACA
TTTCCGGGCAGCTAGACTTGTCTGCTTACACGGAAAGCATCTGCTTGCCAATTTTGGATGGCTTGCTGCACTGGATGGTGTGCCCGTCTG
CAGAGGCACAAGATCCCTTTCCAACTGTGGGACCCAACTCGGTCCTGTCGCCTCAGAGACTTGTGCTGGAGACCCTCTGTAAACTCAGTA
TCCAGGACAATAATGTGGACCTGATCTTGGCCACTCCTCCATTTAGTCGTCAGGAGAAATTCTATGCTACATTAGTTAGGTACGTTGGGG
ATCGCAAAAACCCAGTCTGTCGAGAAATGTCCATGGCGCTTTTATCGAACCTTGCCCAAGGGGACGCACTAGCAGCAAGGGCCATAGCTG
TGCAGAAAGGAAGCATTGGAAACTTGATAAGCTTCCTAGAGGATGGGGTCACGATGGCCCAGTACCAGCAGAGCCAGCACAACCTCATGC
ACATGCAGCCCCCGCCCCTGGAACCACCTAGCGTAGACATGATGTGCAGGGCGGCCAAGGCTTTGCTAGCCATGGCCAGAGTGGACGAAA
ACCGCTCGGAATTCCTTTTGCACGAGGGCCGGTTGCTGGATATCTCGATATCAGCTGTCCTGAACTCTCTGGTTGCATCTGTCATCTGTG
ATGTACTGTTTCAGATTGGGCAGTTATGACATAAGTGAGAAGGCAAGCATGTGTGAGTGAAGATTAGAGGGTCACATATAACTGGCTGTT
TTCTGTTCTTGTTTATCCAGCGTAGGAAGAAGGAAAAGAAAATCTTTGCTCCTCTGCCCCATTCACTATTTACCAATTGGGAATTAAAGA
AATAATTAATTTGAACAGTTATGAAATTAATATTTGCTGTCTGTGTGTATAAGTACATCCTTTGGGGTTTTTTTTTTCTCTTTTTTTTAA
CCAAAGTTGCTGTCTAGTGCATTCAAAGGTCACTTTTTGTTCTTCACAGATCTTTTTAATGTTCTTTCCCATGTTGTATTGCATTTTTGG
GGGAAGCAAATTGACTTTAAAGAAAAAAGTTGTGGCAAAAGATGCTAAGATGCGAAAATTTCACCACACTGAGTCAAAAAGGTGAAAAAT
TATCCATTTCCTATGCGTTTTACTCCTCAGAGAATGAAAAAAACTGCATCCCATCACCCAAAGTTCTGTGCAATAGAAATTTCTACAGAT
ACAGGTATAGGGGCTCAAGGAGGTATGTCGGTCAGTAGTCAAAACTATGAAATGATACTGGTTTCTCCACAGGAATATGGTTCCATTAGG
CTGGGAGCAAAAACAATGTTTTTTAAGATTGAGAATACATACCTGACAACGATCCGGAAACTGCTCCTCACCACTCCCGTCATGCCTGCT
GTCGGCGTTTGACCTTCCACGTGACAGTTCTTCACAATTCCTTTCATCATTTTTTAAATATTTTTTTTACTGCCTATGGGCTGTGATGTA
TATAGAAGTTGTACATTAAACATACCCTCATTTTTTTCTTTTCTTTTTTTTTTTTTTTTTTAGTACAAAGTTTTAGTTTCTTTTTCATGA
TGTGGTAACTACGAAGTGATGGTAGATTTAAATAATTTTTTATTTTTATTTTATATATTTTTTCATTAGGGCCATATCTCCAAAAAAAGA
AAGAAAAAATACAAAAAACAAAAACAAAAAAAAAAGAGGGTAATGTACAAGTTTCTGTATGTATAAAGTCATGCTCGATTTCAGGAGAGC
AGCTGATCACAATTTGCTTCATGAATCAAGGTGTGGAAATGGTTATATATGGATTGATTTAGAAAATGGTTACCAGTACAGTCAAAAAAG
AGAAAATGAAAAAAATACAACTAAAAGGAAGAAACACAACTTCAAAGATTTTTCAGTGATGAGAATCCACATTTGTATTTCAAGATAATG
TAGTTTAAAAAAAAAAAAAAGAAAAAAACTTGATGTAAATTCCTCCTTTTCCTCTGGCTTAATGAATATCATTTATTCAGTATAAAATCT

>38471_38471_1_IGF1R-ARID1B_IGF1R_chr15_99251336_ENST00000268035_ARID1B_chr6_157469758_ENST00000275248_length(amino acids)=1665AA_BP=214
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRV
AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKSNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR
PFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPY
SMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSIS
SPGWPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRE
LATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPT
PASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNS
SMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNM
QYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGP
TQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPF
LPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYD
DSTVATFNLSQLSGFLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEK
TESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRR
RPPPPLSSAGRKKEQEGKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLCTI
AHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNT
LVTLANISGQLDLSAYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYAT
LVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLA

--------------------------------------------------------------
>38471_38471_2_IGF1R-ARID1B_IGF1R_chr15_99251336_ENST00000268035_ARID1B_chr6_157469758_ENST00000346085_length(transcript)=8338nt_BP=1251nt
GGGAAGGAGCTCGCCGCGGCGGCGGCGGCGCTGAGGGAGGAGGCGGCGGCGAGCGGAGCCAGGAGGAGGAGGAGGAGGGGGAGCCGCTCA
TTCATTTTGACTCCGCGTTTCTGCCCCTCGCCGGCCTCGCCTGTGACCCGGACTTCGGGGCGATCTTGCGAACTGCGTCGCGCCCTCCCG
CGGCGGAAGCTCGGGCGTCCGGCCGCCTCCCGCGCGGCCAGGGCCGGGCTTGTTTTTCCTCGCCTAGGCAGATTTGGGCTTTGCCCCCTT
TCTTTGCAGTTTTCCCCCCTTCCTGCCTCTCCGGGTTTGAAAATGGAGGCCGACGACGCCGACAGCCCGCCCCGGCGCGCCTCGGGTTCC
CGACTCCGCCGAGCCCTGGGCCGCTGCTGCCGGCGCTGAGGGGCCGCCCCGCGCCGCCCGCCCCGTCCGCGCACCCGGAGGGCCCCGGCG
GCGCCGCCTTCGGAGTATTGTTTCCTTCGCCCTTGTTTTTGGAGGGGGAGCGAAGACTGAGTTTGAGACTTGTTTCCTTTCATTTCCTTT
TTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGAAAGGGGAATTTCATCCCAAATAAAAGGAATGAAGTCTGGCTCCGGAG
GAGGGTCCCCGACCTCGCTGTGGGGGCTCCTGTTTCTCTCCGCCGCGCTCTCGCTCTGGCCGACGAGTGGAGAAATCTGCGGGCCAGGCA
TCGACATCCGCAACGACTATCAGCAGCTGAAGCGCCTGGAGAACTGCACGGTGATCGAGGGCTACCTCCACATCCTGCTCATCTCCAAGG
CCGAGGACTACCGCAGCTACCGCTTCCCCAAGCTCACGGTCATTACCGAGTACTTGCTGCTGTTCCGAGTGGCTGGCCTCGAGAGCCTCG
GAGACCTCTTCCCCAACCTCACGGTCATCCGCGGCTGGAAACTCTTCTACAACTACGCCCTGGTCATCTTCGAGATGACCAATCTCAAGG
ATATTGGGCTTTACAACCTGAGGAACATTACTCGGGGGGCCATCAGGATTGAGAAAAATGCTGACCTCTGTTACCTCTCCACTGTGGACT
GGTCCCTGATCCTGGATGCGGTGTCCAATAACTACATTGTGGGGAATAAGCCCCCAAAGGAATGTGGGGACCTGTGTCCAGGGACCATGG
AGGAGAAGCCGATGTGTGAGAAGACCACCATCAACAATGAGTACAACTACCGCTGCTGGACCACAAACCGCTGCCAGAAAAGTAACTACT
CCAGACCCCCAGCGTATAGTGGGGTGCCCAGTGCAAGCTACAGCGGCCCAGGGCCCGGTATGGGTATCAGTGCCAACAACCAGATGCATG
GACAAGGGCCAAGCCAGCCATGTGGTGCTGTGCCCCTGGGACGAATGCCATCAGCTGGGATGCAGAACAGACCATTTCCTGGAAATATGA
GCAGCATGACCCCCAGTTCTCCTGGCATGTCTCAGCAGGGAGGGCCAGGAATGGGGCCGCCAATGCCAACTGTGAACCGTAAGGCACAGG
AGGCAGCCGCAGCAGTGATGCAGGCTGCTGCGAACTCAGCACAAAGCAGGCAAGGCAGTTTCCCCGGCATGAACCAGAGTGGACTTATGG
CTTCCAGCTCTCCCTACAGCCAGCCCATGAACAACAGCTCTAGCCTGATGAACACGCAGGCGCCGCCCTACAGCATGGCGCCCGCCATGG
TGAACAGCTCGGCAGCATCTGTGGGTCTTGCAGATATGATGTCTCCTGGTGAATCCAAACTGCCCCTGCCTCTCAAAGCAGACGGCAAAG
AAGAAGGCACTCCACAGCCCGAGAGCAAGTCAAAGAAGTCCAGCTCCTCCACCACTACTGGGGAGAAGATCACGAAGGTGTACGAGCTGG
GGAATGAGCCAGAGAGAAAGCTCTGGGTCGACCGATACCTCACCTTCATGGAAGAGAGAGGCTCTCCTGTCTCAAGTCTGCCTGCCGTGG
GCAAGAAGCCCCTGGACCTGTTCCGACTCTACGTCTGCGTCAAAGAGATCGGGGGTTTGGCCCAGGTTAATAAAAACAAGAAGTGGCGTG
AGCTGGCAACCAACCTAAACGTTGGCACCTCAAGCAGTGCAGCGAGCTCCCTGAAAAAGCAGTATATTCAGTACCTGTTTGCCTTTGAGT
GCAAGATCGAACGTGGGGAGGAGCCCCCGCCGGAAGTCTTCAGCACCGGGGACACCAAAAAGCAGCCCAAGCTCCAGCCGCCATCTCCTG
CTAACTCGGGATCCTTGCAAGGCCCACAGACCCCCCAGTCAACTGGCAGCAATTCCATGGCAGAGGTTCCAGGTGACCTGAAGCCACCTA
CCCCAGCCTCCACCCCTCACGGCCAGATGACTCCAATGCAAGGTGGAAGAAGCAGTACAATCAGTGTGCACGACCCATTCTCAGATGTGA
GTGATTCATCCTTCCCGAAACGGAACTCCATGACTCCAAACGCCCCCTACCAGCAGGGCATGAGCATGCCCGATGTGATGGGCAGGATGC
CCTATGAGCCCAACAAGGACCCCTTTGGGGGAATGAGAAAAGTGCCTGGAAGCAGCGAGCCCTTTATGACGCAAGGACAGATGCCCAACA
GCAGCATGCAGGACATGTACAACCAAAGTCCCTCCGGAGCAATGTCTAACCTGGGCATGGGGCAGCGCCAGCAGTTTCCCTATGGAGCCA
GTTACGACCGAAGGCATGAACCTTATGGGCAGCAGTATCCAGGCCAAGGCCCTCCCTCGGGACAGCCGCCGTATGGAGGGCACCAGCCCG
GCCTGTACCCACAGCAGCCGAATTACAAACGCCATATGGACGGCATGTACGGGCCCCCAGCCAAGCGCCACGAGGGCGACATGTACAACA
TGCAGTACAGCAGCCAGCAGCAGGAGATGTACAACCAGTATGGAGGCTCCTACTCGGGCCCGGACCGCAGGCCCATCCAGGGCCAGTACC
CGTATCCCTACAGCAGGGAGAGGATGCAGGGCCCGGGGCAGATCCAGACACACGGAATCCCGCCTCAGATGATGGGCGGCCCGCTGCAGT
CGTCCTCCAGTGAGGGGCCTCAGCAGAATATGTGGGCAGCACGCAATGATATGCCTTATCCCTACCAGAACAGGCAGGGCCCTGGCGGCC
CTACACAGGCGCCCCCTTACCCAGGCATGAACCGCACAGACGATATGATGGTACCCGATCAGAGGATAAATCATGAGAGCCAGTGGCCTT
CTCACGTCAGCCAGCGTCAGCCTTATATGTCGTCCTCAGCCTCCATGCAGCCCATCACACGCCCACCACAGCCGTCCTACCAGACGCCAC
CGTCACTGCCAAATCACATCTCCAGGGCGCCCAGCCCAGCGTCCTTCCAGCGCTCCCTGGAGAACCGCATGTCTCCAAGCAAGTCTCCTT
TTCTGCCGTCTATGAAGATGCAGAAGGTCATGCCCACGGTCCCCACATCCCAGGTCACCGGGCCACCACCCCAACCACCCCCAATCAGAA
GGGAGATCACCTTTCCTCCTGGCTCAGTAGAAGCATCACAACCAGTCTTGAAACAAAGGCGAAAGATTACCTCCAAAGATATCGTTACTC
CTGAGGCGTGGCGTGTGATGATGTCCCTTAAATCAGGTCTTTTGGCTGAGAGTACGTGGGCTTTGGACACTATTAATATTCTTCTGTATG
ATGACAGCACTGTTGCTACTTTCAATCTCTCCCAGTTGTCTGGATTTCTCGAACTTTTAGTCGAGTACTTTAGAAAATGCCTGATTGACA
TTTTTGGAATTCTTATGGAATATGAAGTGGGAGACCCCAGCCAAAAAGCACTTGATCACAACGCAGCAAGGAAGGATGACAGCCAGTCCT
TGGCAGACGATTCTGGGAAAGAGGAGGAAGATGCTGAATGTATTGATGACGACGAGGAAGACGAGGAGGATGAGGAGGAAGACAGCGAGA
AGACAGAAAGCGATGAAAAGAGCAGCATCGCTCTGACTGCCCCGGACGCCGCTGCAGACCCAAAGGAGAAGCCCAAGCAAGCCAGTAAGT
TCGACAAGCTGCCAATAAAGATAGTCAAAAAGAACAACCTGTTTGTTGTTGACCGATCTGACAAGTTGGGGCGTGTGCAGGAGTTCAATA
GTGGCCTTCTGCACTGGCAGCTCGGCGGGGGTGACACCACCGAGCACATTCAGACTCACTTTGAGAGCAAGATGGAAATTCCTCCTCGCA
GGCGCCCACCTCCCCCCTTAAGCTCCGCAGGTAGAAAGAAAGAGCAAGAAGGCAAAGGCGACTCTGAAGAGCAGCAAGAGAAAAGCATCA
TAGCAACCATCGATGACGTCCTCTCTGCTCGGCCAGGGGCATTGCCTGAAGACGCAAACCCTGGGCCCCAGACCGAAAGCAGTAAGTTTC
CCTTTGGTATCCAGCAAGCCAAAAGTCACCGGAACATCAAGCTGCTGGAGGACGAGCCCAGGAGCCGAGACGAGACTCCTCTGTGTACCA
TCGCGCACTGGCAGGACTCGCTGGCTAAGCGATGCATCTGTGTGTCCAATATTGTCCGTAGCTTGTCATTCGTGCCTGGCAATGATGCCG
AAATGTCCAAACATCCAGGCCTGGTGCTGATCCTGGGGAAGCTGATTCTTCTTCACCACGAGCATCCAGAGAGAAAGCGAGCACCGCAGA
CCTATGAGAAAGAGGAGGATGAGGACAAGGGGGTGGCCTGCAGCAAAGATGAGTGGTGGTGGGACTGCCTCGAGGTCTTGAGGGATAACA
CGTTGGTCACGTTGGCCAACATTTCCGGGCAGCTAGACTTGTCTGCTTACACGGAAAGCATCTGCTTGCCAATTTTGGATGGCTTGCTGC
ACTGGATGGTGTGCCCGTCTGCAGAGGCACAAGATCCCTTTCCAACTGTGGGACCCAACTCGGTCCTGTCGCCTCAGAGACTTGTGCTGG
AGACCCTCTGTAAACTCAGTATCCAGGACAATAATGTGGACCTGATCTTGGCCACTCCTCCATTTAGTCGTCAGGAGAAATTCTATGCTA
CATTAGTTAGGTACGTTGGGGATCGCAAAAACCCAGTCTGTCGAGAAATGTCCATGGCGCTTTTATCGAACCTTGCCCAAGGGGACGCAC
TAGCAGCAAGGGCCATAGCTGTGCAGAAAGGAAGCATTGGAAACTTGATAAGCTTCCTAGAGGATGGGGTCACGATGGCCCAGTACCAGC
AGAGCCAGCACAACCTCATGCACATGCAGCCCCCGCCCCTGGAACCACCTAGCGTAGACATGATGTGCAGGGCGGCCAAGGCTTTGCTAG
CCATGGCCAGAGTGGACGAAAACCGCTCGGAATTCCTTTTGCACGAGGGCCGGTTGCTGGATATCTCGATATCAGCTGTCCTGAACTCTC
TGGTTGCATCTGTCATCTGTGATGTACTGTTTCAGATTGGGCAGTTATGACATAAGTGAGAAGGCAAGCATGTGTGAGTGAAGATTAGAG
GGTCACATATAACTGGCTGTTTTCTGTTCTTGTTTATCCAGCGTAGGAAGAAGGAAAAGAAAATCTTTGCTCCTCTGCCCCATTCACTAT
TTACCAATTGGGAATTAAAGAAATAATTAATTTGAACAGTTATGAAATTAATATTTGCTGTCTGTGTGTATAAGTACATCCTTTGGGGTT
TTTTTTTTCTCTTTTTTTTAACCAAAGTTGCTGTCTAGTGCATTCAAAGGTCACTTTTTGTTCTTCACAGATCTTTTTAATGTTCTTTCC
CATGTTGTATTGCATTTTTGGGGGAAGCAAATTGACTTTAAAGAAAAAAGTTGTGGCAAAAGATGCTAAGATGCGAAAATTTCACCACAC
TGAGTCAAAAAGGTGAAAAATTATCCATTTCCTATGCGTTTTACTCCTCAGAGAATGAAAAAAACTGCATCCCATCACCCAAAGTTCTGT
GCAATAGAAATTTCTACAGATACAGGTATAGGGGCTCAAGGAGGTATGTCGGTCAGTAGTCAAAACTATGAAATGATACTGGTTTCTCCA
CAGGAATATGGTTCCATTAGGCTGGGAGCAAAAACAATGTTTTTTAAGATTGAGAATACATACCTGACAACGATCCGGAAACTGCTCCTC
ACCACTCCCGTCATGCCTGCTGTCGGCGTTTGACCTTCCACGTGACAGTTCTTCACAATTCCTTTCATCATTTTTTAAATATTTTTTTTA
CTGCCTATGGGCTGTGATGTATATAGAAGTTGTACATTAAACATACCCTCATTTTTTTCTTTTCTTTTTTTTTTTTTTTTTTAGTACAAA
GTTTTAGTTTCTTTTTCATGATGTGGTAACTACGAAGTGATGGTAGATTTAAATAATTTTTTATTTTTATTTTATATATTTTTTCATTAG
GGCCATATCTCCAAAAAAAGAAAGAAAAAATACAAAAAACAAAAACAAAAAAAAAAGAGGGTAATGTACAAGTTTCTGTATGTATAAAGT
CATGCTCGATTTCAGGAGAGCAGCTGATCACAATTTGCTTCATGAATCAAGGTGTGGAAATGGTTATATATGGATTGATTTAGAAAATGG
TTACCAGTACAGTCAAAAAAGAGAAAATGAAAAAAATACAACTAAAAGGAAGAAACACAACTTCAAAGATTTTTCAGTGATGAGAATCCA
CATTTGTATTTCAAGATAATGTAGTTTAAAAAAAAAAAAAAGAAAAAAACTTGATGTAAATTCCTCCTTTTCCTCTGGCTTAATGAATAT
CATTTATTCAGTATAAAATCTTTATATGTTCCACATGTTAAGAATAAATGTACATTAAATCTTGTTAAGCACTGTGATGGGTGTTCTTGA
ATACTGTTCTAGTTTCCTTAAAGTGGTTTCCTAGTAATCAAGTTATTTACAAGAAATAGGGGAATGCAGCAGTGTATTCACATTATAAAA
CCCTACATTTGGAAGAGACCTTTAGGGGTTACCTACTTTAGAGTGGGGAGCAACAGTTTGATTTTCTCAAATTACTTAGCTAATTAGTCT
TTCTTTGAAGCAATTAACTCTAACGACATTGAGGTATGATCATTTTCAGTATTTATGGGAGGTGGCTGCTGACCCACTTGAGGTGAGATC
TCAGAAGCTTAACTGGCCTGAAAATGTAACATTCTGCCTTTTACTAACTCCATCTTAGTTTAATCAAAGTTCAATCTATTCCTTGTTTCT
TCTGTGTGCCTCAGAGTTATTTTGCATTTAGTTTACTCCACCGTGTATAATATTTATACTGTGCAATGTTAAAAAAGAATCTGTTATATT
GTATGTGGTGTACATAGTGCAAAGTGATGATTTCTATTTCAGGGCATATTATGGTTCTCATATTCCTTCCTACCTGGTGCACAGTAGCTT
TTTAATACTAGTCACTTCTAATTTAAACTTTCTCTTCCTGGGTCATTGACTGTTACTGTGTAATAATCGATTTCTTTGAAACTGCTGCAT
AATTATGCTGTTAGTGGACCTCTACCTCTTCTCTTCCCTCTCCCAATCACAGTATACTCAGAATCCCCAGCCCCTCGCATACATTGTGTC
GGTTCACATTACTCACAGTAATATATGGAAGAGTTAGACAAGAACATGCAGTTACAGTCATTGTGAGACGTGACTCTCCAGTGTCACGAG
GAAAAAAATCATCTTTTCTGCAAACAGTCTCTCATCTGTCAACTCCCACATTACTGAGTCAAACAGTCTTCTTACATAACAATGCAACCA
AATATATGTTGAATTAAAGACCCATTTATAATTCTGCTTTAAATACATCTGCTTGCTAAGAACAGATTTCAGTGCTCCAAGCTTCAAATA
TGGAGATTTGTAAGAGGGAATTCAATATTATTCTAATTTCTCTCTTACAGAGTACAAATAAAAGGTGTATACAAACTCCGAACATATCCA
GTATTCCAATTCCTTTGTCAATCAGAAGAGTAAAATAATTAACAAAAGACTGTTGTTATGGTTTGCATTGTAACCGATACGCAGAGTCTG
ACCGTTGGGCAACAAGTTTTTCTATCCTGATGCGCAACACAGTCTCTAGAGACTAATCCAGGAAGACTTTAGCCTCCTTTCCATATTCTC
ACCCCCGAATCAAGATTTACAGAAGCCCACGAAGAATTTACAGCCTGCTTGAGATCATCTTGCCTATAAACTGAGTTATTGCTTTGTCCT
AAAAATTAGTCGGTTTTTTTTTTTCTATGAGGCTTTTCAGAAATTTACAGGATGCCCAGACTTTACATGTGTACCAAAAAAAAAAAAAAG

>38471_38471_2_IGF1R-ARID1B_IGF1R_chr15_99251336_ENST00000268035_ARID1B_chr6_157469758_ENST00000346085_length(amino acids)=1612AA_BP=214
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRV
AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKSNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR
PFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPY
SMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPV
SSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPK
LQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMP
DVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPP
YGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQM
MGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQ
PSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKIT
SKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAAR
KDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLG
RVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQEGKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQ
TESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPE
RKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLS
PQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGV

--------------------------------------------------------------
>38471_38471_3_IGF1R-ARID1B_IGF1R_chr15_99251336_ENST00000268035_ARID1B_chr6_157469758_ENST00000350026_length(transcript)=6709nt_BP=1251nt
GGGAAGGAGCTCGCCGCGGCGGCGGCGGCGCTGAGGGAGGAGGCGGCGGCGAGCGGAGCCAGGAGGAGGAGGAGGAGGGGGAGCCGCTCA
TTCATTTTGACTCCGCGTTTCTGCCCCTCGCCGGCCTCGCCTGTGACCCGGACTTCGGGGCGATCTTGCGAACTGCGTCGCGCCCTCCCG
CGGCGGAAGCTCGGGCGTCCGGCCGCCTCCCGCGCGGCCAGGGCCGGGCTTGTTTTTCCTCGCCTAGGCAGATTTGGGCTTTGCCCCCTT
TCTTTGCAGTTTTCCCCCCTTCCTGCCTCTCCGGGTTTGAAAATGGAGGCCGACGACGCCGACAGCCCGCCCCGGCGCGCCTCGGGTTCC
CGACTCCGCCGAGCCCTGGGCCGCTGCTGCCGGCGCTGAGGGGCCGCCCCGCGCCGCCCGCCCCGTCCGCGCACCCGGAGGGCCCCGGCG
GCGCCGCCTTCGGAGTATTGTTTCCTTCGCCCTTGTTTTTGGAGGGGGAGCGAAGACTGAGTTTGAGACTTGTTTCCTTTCATTTCCTTT
TTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGAAAGGGGAATTTCATCCCAAATAAAAGGAATGAAGTCTGGCTCCGGAG
GAGGGTCCCCGACCTCGCTGTGGGGGCTCCTGTTTCTCTCCGCCGCGCTCTCGCTCTGGCCGACGAGTGGAGAAATCTGCGGGCCAGGCA
TCGACATCCGCAACGACTATCAGCAGCTGAAGCGCCTGGAGAACTGCACGGTGATCGAGGGCTACCTCCACATCCTGCTCATCTCCAAGG
CCGAGGACTACCGCAGCTACCGCTTCCCCAAGCTCACGGTCATTACCGAGTACTTGCTGCTGTTCCGAGTGGCTGGCCTCGAGAGCCTCG
GAGACCTCTTCCCCAACCTCACGGTCATCCGCGGCTGGAAACTCTTCTACAACTACGCCCTGGTCATCTTCGAGATGACCAATCTCAAGG
ATATTGGGCTTTACAACCTGAGGAACATTACTCGGGGGGCCATCAGGATTGAGAAAAATGCTGACCTCTGTTACCTCTCCACTGTGGACT
GGTCCCTGATCCTGGATGCGGTGTCCAATAACTACATTGTGGGGAATAAGCCCCCAAAGGAATGTGGGGACCTGTGTCCAGGGACCATGG
AGGAGAAGCCGATGTGTGAGAAGACCACCATCAACAATGAGTACAACTACCGCTGCTGGACCACAAACCGCTGCCAGAAAAGTAACTACT
CCAGACCCCCAGCGTATAGTGGGGTGCCCAGTGCAAGCTACAGCGGCCCAGGGCCCGGTATGGGTATCAGTGCCAACAACCAGATGCATG
GACAAGGGCCAAGCCAGCCATGTGGTGCTGTGCCCCTGGGACGAATGCCATCAGCTGGGATGCAGAACAGACCATTTCCTGGAAATATGA
GCAGCATGACCCCCAGTTCTCCTGGCATGTCTCAGCAGGGAGGGCCAGGAATGGGGCCGCCAATGCCAACTGTGAACCGTAAGGCACAGG
AGGCAGCCGCAGCAGTGATGCAGGCTGCTGCGAACTCAGCACAAAGCAGGCAAGGCAGTTTCCCCGGCATGAACCAGAGTGGACTTATGG
CTTCCAGCTCTCCCTACAGCCAGCCCATGAACAACAGCTCTAGCCTGATGAACACGCAGGCGCCGCCCTACAGCATGGCGCCCGCCATGG
TGAACAGCTCGGCAGCATCTGTGGGTCTTGCAGATATGATGTCTCCTGGTGAATCCAAACTGCCCCTGCCTCTCAAAGCAGACGGCAAAG
AAGAAGGCACTCCACAGCCCGAGAGCAAGTCAAAGAAGTCCAGCTCCTCCACCACTACTGGGGAGAAGATCACGAAGGTGTACGAGCTGG
GGAATGAGCCAGAGAGAAAGCTCTGGGTCGACCGATACCTCACCTTCATGGAAGAGAGAGGCTCTCCTGTCTCAAGTCTGCCTGCCGTGG
GCAAGAAGCCCCTGGACCTGTTCCGACTCTACGTCTGCGTCAAAGAGATCGGGGGTTTGGCCCAGGTTAATAAAAACAAGAAGTGGCGTG
AGCTGGCAACCAACCTAAACGTTGGCACCTCAAGCAGTGCAGCGAGCTCCCTGAAAAAGCAGTATATTCAGTACCTGTTTGCCTTTGAGT
GCAAGATCGAACGTGGGGAGGAGCCCCCGCCGGAAGTCTTCAGCACCGGGGACACCAAAAAGCAGCCCAAGCTCCAGCCGCCATCTCCTG
CTAACTCGGGATCCTTGCAAGGCCCACAGACCCCCCAGTCAACTGGCAGCAATTCCATGGCAGAGGTTCCAGGTGACCTGAAGCCACCTA
CCCCAGCCTCCACCCCTCACGGCCAGATGACTCCAATGCAAGGTGGAAGAAGCAGTACAATCAGTGTGCACGACCCATTCTCAGATGTGA
GTGATTCATCCTTCCCGAAACGGAACTCCATGACTCCAAACGCCCCCTACCAGCAGGGCATGAGCATGCCCGATGTGATGGGCAGGATGC
CCTATGAGCCCAACAAGGACCCCTTTGGGGGAATGAGAAAAGTGCCTGGAAGCAGCGAGCCCTTTATGACGCAAGGACAGATGCCCAACA
GCAGCATGCAGGACATGTACAACCAAAGTCCCTCCGGAGCAATGTCTAACCTGGGCATGGGGCAGCGCCAGCAGTTTCCCTATGGAGCCA
GTTACGACCGAAGGCATGAACCTTATGGGCAGCAGTATCCAGGCCAAGGCCCTCCCTCGGGACAGCCGCCGTATGGAGGGCACCAGCCCG
GCCTGTACCCACAGCAGCCGAATTACAAACGCCATATGGACGGCATGTACGGGCCCCCAGCCAAGCGCCACGAGGGCGACATGTACAACA
TGCAGTACAGCAGCCAGCAGCAGGAGATGTACAACCAGTATGGAGGCTCCTACTCGGGCCCGGACCGCAGGCCCATCCAGGGCCAGTACC
CGTATCCCTACAGCAGGGAGAGGATGCAGGGCCCGGGGCAGATCCAGACACACGGAATCCCGCCTCAGATGATGGGCGGCCCGCTGCAGT
CGTCCTCCAGTGAGGGGCCTCAGCAGAATATGTGGGCAGCACGCAATGATATGCCTTATCCCTACCAGAACAGGCAGGGCCCTGGCGGCC
CTACACAGGCGCCCCCTTACCCAGGCATGAACCGCACAGACGATATGATGGTACCCGATCAGAGGATAAATCATGAGAGCCAGTGGCCTT
CTCACGTCAGCCAGCGTCAGCCTTATATGTCGTCCTCAGCCTCCATGCAGCCCATCACACGCCCACCACAGCCGTCCTACCAGACGCCAC
CGTCACTGCCAAATCACATCTCCAGGGCGCCCAGCCCAGCGTCCTTCCAGCGCTCCCTGGAGAACCGCATGTCTCCAAGCAAGTCTCCTT
TTCTGCCGTCTATGAAGATGCAGAAGGTCATGCCCACGGTCCCCACATCCCAGGTCACCGGGCCACCACCCCAACCACCCCCAATCAGAA
GGGAGATCACCTTTCCTCCTGGCTCAGTAGAAGCATCACAACCAGTCTTGAAACAAAGGCGAAAGATTACCTCCAAAGATATCGTTACTC
CTGAGGCGTGGCGTGTGATGATGTCCCTTAAATCAGGTCTTTTGGCTGAGAGTACGTGGGCTTTGGACACTATTAATATTCTTCTGTATG
ATGACAGCACTGTTGCTACTTTCAATCTCTCCCAGTTGTCTGGATTTCTCGAACTTTTAGTCGAGTACTTTAGAAAATGCCTGATTGACA
TTTTTGGAATTCTTATGGAATATGAAGTGGGAGACCCCAGCCAAAAAGCACTTGATCACAACGCAGCAAGGAAGGATGACAGCCAGTCCT
TGGCAGACGATTCTGGGAAAGAGGAGGAAGATGCTGAATGTATTGATGACGACGAGGAAGACGAGGAGGATGAGGAGGAAGACAGCGAGA
AGACAGAAAGCGATGAAAAGAGCAGCATCGCTCTGACTGCCCCGGACGCCGCTGCAGACCCAAAGGAGAAGCCCAAGCAAGCCAGTAAGT
TCGACAAGCTGCCAATAAAGATAGTCAAAAAGAACAACCTGTTTGTTGTTGACCGATCTGACAAGTTGGGGCGTGTGCAGGAGTTCAATA
GTGGCCTTCTGCACTGGCAGCTCGGCGGGGGTGACACCACCGAGCACATTCAGACTCACTTTGAGAGCAAGATGGAAATTCCTCCTCGCA
GGCGCCCACCTCCCCCCTTAAGCTCCGCAGGTAGAAAGAAAGAGCAAGAAGGCAAAGGCGACTCTGAAGAGCAGCAAGAGAAAAGCATCA
TAGCAACCATCGATGACGTCCTCTCTGCTCGGCCAGGGGCATTGCCTGAAGACGCAAACCCTGGGCCCCAGACCGAAAGCAGTAAGTTTC
CCTTTGGTATCCAGCAAGCCAAAAGTCACCGGAACATCAAGCTGCTGGAGGACGAGCCCAGGAGCCGAGACGAGACTCCTCTGTGTACCA
TCGCGCACTGGCAGGACTCGCTGGCTAAGCGATGCATCTGTGTGTCCAATATTGTCCGTAGCTTGTCATTCGTGCCTGGCAATGATGCCG
AAATGTCCAAACATCCAGGCCTGGTGCTGATCCTGGGGAAGCTGATTCTTCTTCACCACGAGCATCCAGAGAGAAAGCGAGCACCGCAGA
CCTATGAGAAAGAGGAGGATGAGGACAAGGGGGTGGCCTGCAGCAAAGATGAGTGGTGGTGGGACTGCCTCGAGGTCTTGAGGGATAACA
CGTTGGTCACGTTGGCCAACATTTCCGGGCAGCTAGACTTGTCTGCTTACACGGAAAGCATCTGCTTGCCAATTTTGGATGGCTTGCTGC
ACTGGATGGTGTGCCCGTCTGCAGAGGCACAAGATCCCTTTCCAACTGTGGGACCCAACTCGGTCCTGTCGCCTCAGAGACTTGTGCTGG
AGACCCTCTGTAAACTCAGTATCCAGGACAATAATGTGGACCTGATCTTGGCCACTCCTCCATTTAGTCGTCAGGAGAAATTCTATGCTA
CATTAGTTAGGTACGTTGGGGATCGCAAAAACCCAGTCTGTCGAGAAATGTCCATGGCGCTTTTATCGAACCTTGCCCAAGGGGACGCAC
TAGCAGCAAGGGCCATAGCTGTGCAGAAAGGAAGCATTGGAAACTTGATAAGCTTCCTAGAGGATGGGGTCACGATGGCCCAGTACCAGC
AGAGCCAGCACAACCTCATGCACATGCAGCCCCCGCCCCTGGAACCACCTAGCGTAGACATGATGTGCAGGGCGGCCAAGGCTTTGCTAG
CCATGGCCAGAGTGGACGAAAACCGCTCGGAATTCCTTTTGCACGAGGGCCGGTTGCTGGATATCTCGATATCAGCTGTCCTGAACTCTC
TGGTTGCATCTGTCATCTGTGATGTACTGTTTCAGATTGGGCAGTTATGACATAAGTGAGAAGGCAAGCATGTGTGAGTGAAGATTAGAG
GGTCACATATAACTGGCTGTTTTCTGTTCTTGTTTATCCAGCGTAGGAAGAAGGAAAAGAAAATCTTTGCTCCTCTGCCCCATTCACTAT
TTACCAATTGGGAATTAAAGAAATAATTAATTTGAACAGTTATGAAATTAATATTTGCTGTCTGTGTGTATAAGTACATCCTTTGGGGTT
TTTTTTTTCTCTTTTTTTTAACCAAAGTTGCTGTCTAGTGCATTCAAAGGTCACTTTTTGTTCTTCACAGATCTTTTTAATGTTCTTTCC
CATGTTGTATTGCATTTTTGGGGGAAGCAAATTGACTTTAAAGAAAAAAGTTGTGGCAAAAGATGCTAAGATGCGAAAATTTCACCACAC
TGAGTCAAAAAGGTGAAAAATTATCCATTTCCTATGCGTTTTACTCCTCAGAGAATGAAAAAAACTGCATCCCATCACCCAAAGTTCTGT
GCAATAGAAATTTCTACAGATACAGGTATAGGGGCTCAAGGAGGTATGTCGGTCAGTAGTCAAAACTATGAAATGATACTGGTTTCTCCA
CAGGAATATGGTTCCATTAGGCTGGGAGCAAAAACAATGTTTTTTAAGATTGAGAATACATACCTGACAACGATCCGGAAACTGCTCCTC
ACCACTCCCGTCATGCCTGCTGTCGGCGTTTGACCTTCCACGTGACAGTTCTTCACAATTCCTTTCATCATTTTTTAAATATTTTTTTTA
CTGCCTATGGGCTGTGATGTATATAGAAGTTGTACATTAAACATACCCTCATTTTTTTCTTTTCTTTTTTTTTTTTTTTTTTAGTACAAA
GTTTTAGTTTCTTTTTCATGATGTGGTAACTACGAAGTGATGGTAGATTTAAATAATTTTTTATTTTTATTTTATATATTTTTTCATTAG
GGCCATATCTCCAAAAAAAGAAAGAAAAAATACAAAAAACAAAAACAAAAAAAAAAGAGGGTAATGTACAAGTTTCTGTATGTATAAAGT
CATGCTCGATTTCAGGAGAGCAGCTGATCACAATTTGCTTCATGAATCAAGGTGTGGAAATGGTTATATATGGATTGATTTAGAAAATGG
TTACCAGTACAGTCAAAAAAGAGAAAATGAAAAAAATACAACTAAAAGGAAGAAACACAACTTCAAAGATTTTTCAGTGATGAGAATCCA

>38471_38471_3_IGF1R-ARID1B_IGF1R_chr15_99251336_ENST00000268035_ARID1B_chr6_157469758_ENST00000350026_length(amino acids)=1612AA_BP=214
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRV
AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKSNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR
PFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPY
SMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPV
SSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPK
LQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMP
DVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPP
YGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQM
MGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQ
PSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKIT
SKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAAR
KDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLG
RVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQEGKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQ
TESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPE
RKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLS
PQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGV

--------------------------------------------------------------
>38471_38471_4_IGF1R-ARID1B_IGF1R_chr15_99251336_ENST00000268035_ARID1B_chr6_157469758_ENST00000367148_length(transcript)=6985nt_BP=1251nt
GGGAAGGAGCTCGCCGCGGCGGCGGCGGCGCTGAGGGAGGAGGCGGCGGCGAGCGGAGCCAGGAGGAGGAGGAGGAGGGGGAGCCGCTCA
TTCATTTTGACTCCGCGTTTCTGCCCCTCGCCGGCCTCGCCTGTGACCCGGACTTCGGGGCGATCTTGCGAACTGCGTCGCGCCCTCCCG
CGGCGGAAGCTCGGGCGTCCGGCCGCCTCCCGCGCGGCCAGGGCCGGGCTTGTTTTTCCTCGCCTAGGCAGATTTGGGCTTTGCCCCCTT
TCTTTGCAGTTTTCCCCCCTTCCTGCCTCTCCGGGTTTGAAAATGGAGGCCGACGACGCCGACAGCCCGCCCCGGCGCGCCTCGGGTTCC
CGACTCCGCCGAGCCCTGGGCCGCTGCTGCCGGCGCTGAGGGGCCGCCCCGCGCCGCCCGCCCCGTCCGCGCACCCGGAGGGCCCCGGCG
GCGCCGCCTTCGGAGTATTGTTTCCTTCGCCCTTGTTTTTGGAGGGGGAGCGAAGACTGAGTTTGAGACTTGTTTCCTTTCATTTCCTTT
TTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGAAAGGGGAATTTCATCCCAAATAAAAGGAATGAAGTCTGGCTCCGGAG
GAGGGTCCCCGACCTCGCTGTGGGGGCTCCTGTTTCTCTCCGCCGCGCTCTCGCTCTGGCCGACGAGTGGAGAAATCTGCGGGCCAGGCA
TCGACATCCGCAACGACTATCAGCAGCTGAAGCGCCTGGAGAACTGCACGGTGATCGAGGGCTACCTCCACATCCTGCTCATCTCCAAGG
CCGAGGACTACCGCAGCTACCGCTTCCCCAAGCTCACGGTCATTACCGAGTACTTGCTGCTGTTCCGAGTGGCTGGCCTCGAGAGCCTCG
GAGACCTCTTCCCCAACCTCACGGTCATCCGCGGCTGGAAACTCTTCTACAACTACGCCCTGGTCATCTTCGAGATGACCAATCTCAAGG
ATATTGGGCTTTACAACCTGAGGAACATTACTCGGGGGGCCATCAGGATTGAGAAAAATGCTGACCTCTGTTACCTCTCCACTGTGGACT
GGTCCCTGATCCTGGATGCGGTGTCCAATAACTACATTGTGGGGAATAAGCCCCCAAAGGAATGTGGGGACCTGTGTCCAGGGACCATGG
AGGAGAAGCCGATGTGTGAGAAGACCACCATCAACAATGAGTACAACTACCGCTGCTGGACCACAAACCGCTGCCAGAAAAGTAACTACT
CCAGACCCCCAGCGTATAGTGGGGTGCCCAGTGCAAGCTACAGCGGCCCAGGGCCCGGTATGGGTATCAGTGCCAACAACCAGATGCATG
GACAAGGGCCAAGCCAGCCATGTGGTGCTGTGCCCCTGGGACGAATGCCATCAGCTGGGATGCAGAACAGACCATTTCCTGGAAATATGA
GCAGCATGACCCCCAGTTCTCCTGGCATGTCTCAGCAGGGAGGGCCAGGAATGGGGCCGCCAATGCCAACTGTGAACCGTAAGGCACAGG
AGGCAGCCGCAGCAGTGATGCAGGCTGCTGCGAACTCAGCACAAAGCAGGCAAGGCAGTTTCCCCGGCATGAACCAGAGTGGACTTATGG
CTTCCAGCTCTCCCTACAGCCAGCCCATGAACAACAGCTCTAGCCTGATGAACACGCAGGCGCCGCCCTACAGCATGGCGCCCGCCATGG
TGAACAGCTCGGCAGCATCTGTGGGTCTTGCAGATATGATGTCTCCTGGTGAATCCAAACTGCCCCTGCCTCTCAAAGCAGACGGCAAAG
AAGAAGGCACTCCACAGCCCGAGAGCAAGTCAAAGGATAGCTACAGCTCTCAGGGTATTTCTCAGCCCCCAACCCCAGGCAACCTGCCAG
TCCCTTCCCCAATGTCCCCCAGCTCTGCTAGCATCTCCTCATTTCATGGAGATGAAAGTGATAGCATTAGCAGCCCAGGCTGGCCAAAGA
CTCCATCAAGCCCTAAGTCCAGCTCCTCCACCACTACTGGGGAGAAGATCACGAAGGTGTACGAGCTGGGGAATGAGCCAGAGAGAAAGC
TCTGGGTCGACCGATACCTCACCTTCATGGAAGAGAGAGGCTCTCCTGTCTCAAGTCTGCCTGCCGTGGGCAAGAAGCCCCTGGACCTGT
TCCGACTCTACGTCTGCGTCAAAGAGATCGGGGGTTTGGCCCAGGTTAATAAAAACAAGAAGTGGCGTGAGCTGGCAACCAACCTAAACG
TTGGCACCTCAAGCAGTGCAGCGAGCTCCCTGAAAAAGCAGTATATTCAGTACCTGTTTGCCTTTGAGTGCAAGATCGAACGTGGGGAGG
AGCCCCCGCCGGAAGTCTTCAGCACCGGGGACACCAAAAAGCAGCCCAAGCTCCAGCCGCCATCTCCTGCTAACTCGGGATCCTTGCAAG
GCCCACAGACCCCCCAGTCAACTGGCAGCAATTCCATGGCAGAGGTTCCAGGTGACCTGAAGCCACCTACCCCAGCCTCCACCCCTCACG
GCCAGATGACTCCAATGCAAGGTGGAAGAAGCAGTACAATCAGTGTGCACGACCCATTCTCAGATGTGAGTGATTCATCCTTCCCGAAAC
GGAACTCCATGACTCCAAACGCCCCCTACCAGCAGGGCATGAGCATGCCCGATGTGATGGGCAGGATGCCCTATGAGCCCAACAAGGACC
CCTTTGGGGGAATGAGAAAAGTGCCTGGAAGCAGCGAGCCCTTTATGACGCAAGGACAGATGCCCAACAGCAGCATGCAGGACATGTACA
ACCAAAGTCCCTCCGGAGCAATGTCTAACCTGGGCATGGGGCAGCGCCAGCAGTTTCCCTATGGAGCCAGTTACGACCGAAGGCATGAAC
CTTATGGGCAGCAGTATCCAGGCCAAGGCCCTCCCTCGGGACAGCCGCCGTATGGAGGGCACCAGCCCGGCCTGTACCCACAGCAGCCGA
ATTACAAACGCCATATGGACGGCATGTACGGGCCCCCAGCCAAGCGCCACGAGGGCGACATGTACAACATGCAGTACAGCAGCCAGCAGC
AGGAGATGTACAACCAGTATGGAGGCTCCTACTCGGGCCCGGACCGCAGGCCCATCCAGGGCCAGTACCCGTATCCCTACAGCAGGGAGA
GGATGCAGGGCCCGGGGCAGATCCAGACACACGGAATCCCGCCTCAGATGATGGGCGGCCCGCTGCAGTCGTCCTCCAGTGAGGGGCCTC
AGCAGAATATGTGGGCAGCACGCAATGATATGCCTTATCCCTACCAGAACAGGCAGGGCCCTGGCGGCCCTACACAGGCGCCCCCTTACC
CAGGCATGAACCGCACAGACGATATGATGGTACCCGATCAGAGGATAAATCATGAGAGCCAGTGGCCTTCTCACGTCAGCCAGCGTCAGC
CTTATATGTCGTCCTCAGCCTCCATGCAGCCCATCACACGCCCACCACAGCCGTCCTACCAGACGCCACCGTCACTGCCAAATCACATCT
CCAGGGCGCCCAGCCCAGCGTCCTTCCAGCGCTCCCTGGAGAACCGCATGTCTCCAAGCAAGTCTCCTTTTCTGCCGTCTATGAAGATGC
AGAAGGTCATGCCCACGGTCCCCACATCCCAGGTCACCGGGCCACCACCCCAACCACCCCCAATCAGAAGGGAGATCACCTTTCCTCCTG
GCTCAGTAGAAGCATCACAACCAGTCTTGAAACAAAGGCGAAAGATTACCTCCAAAGATATCGTTACTCCTGAGGCGTGGCGTGTGATGA
TGTCCCTTAAATCAGGTCTTTTGGCTGAGAGTACGTGGGCTTTGGACACTATTAATATTCTTCTGTATGATGACAGCACTGTTGCTACTT
TCAATCTCTCCCAGTTGTCTGGATTTCTCGAACTTTTAGTCGAGTACTTTAGAAAATGCCTGATTGACATTTTTGGAATTCTTATGGAAT
ATGAAGTGGGAGACCCCAGCCAAAAAGCACTTGATCACAACGCAGCAAGGAAGGATGACAGCCAGTCCTTGGCAGACGATTCTGGGAAAG
AGGAGGAAGATGCTGAATGTATTGATGACGACGAGGAAGACGAGGAGGATGAGGAGGAAGACAGCGAGAAGACAGAAAGCGATGAAAAGA
GCAGCATCGCTCTGACTGCCCCGGACGCCGCTGCAGACCCAAAGGAGAAGCCCAAGCAAGCCAGTAAGTTCGACAAGCTGCCAATAAAGA
TAGTCAAAAAGAACAACCTGTTTGTTGTTGACCGATCTGACAAGTTGGGGCGTGTGCAGGAGTTCAATAGTGGCCTTCTGCACTGGCAGC
TCGGCGGGGGTGACACCACCGAGCACATTCAGACTCACTTTGAGAGCAAGATGGAAATTCCTCCTCGCAGGCGCCCACCTCCCCCCTTAA
GCTCCGCAGGTAGAAAGAAAGAGCAAGAAGGCAAAGGCGACTCTGAAGAGCAGCAAGAGAAAAGCATCATAGCAACCATCGATGACGTCC
TCTCTGCTCGGCCAGGGGCATTGCCTGAAGACGCAAACCCTGGGCCCCAGACCGAAAGCAGTAAGTTTCCCTTTGGTATCCAGCAAGCCA
AAAGTCACCGGAACATCAAGCTGCTGGAGGACGAGCCCAGGAGCCGAGACGAGACTCCTCTGTGTACCATCGCGCACTGGCAGGACTCGC
TGGCTAAGCGATGCATCTGTGTGTCCAATATTGTCCGTAGCTTGTCATTCGTGCCTGGCAATGATGCCGAAATGTCCAAACATCCAGGCC
TGGTGCTGATCCTGGGGAAGCTGATTCTTCTTCACCACGAGCATCCAGAGAGAAAGCGAGCACCGCAGACCTATGAGAAAGAGGAGGATG
AGGACAAGGGGGTGGCCTGCAGCAAAGATGAGTGGTGGTGGGACTGCCTCGAGGTCTTGAGGGATAACACGTTGGTCACGTTGGCCAACA
TTTCCGGGCAGCTAGACTTGTCTGCTTACACGGAAAGCATCTGCTTGCCAATTTTGGATGGCTTGCTGCACTGGATGGTGTGCCCGTCTG
CAGAGGCACAAGATCCCTTTCCAACTGTGGGACCCAACTCGGTCCTGTCGCCTCAGAGACTTGTGCTGGAGACCCTCTGTAAACTCAGTA
TCCAGGACAATAATGTGGACCTGATCTTGGCCACTCCTCCATTTAGTCGTCAGGAGAAATTCTATGCTACATTAGTTAGGTACGTTGGGG
ATCGCAAAAACCCAGTCTGTCGAGAAATGTCCATGGCGCTTTTATCGAACCTTGCCCAAGGGGACGCACTAGCAGCAAGGGCCATAGCTG
TGCAGAAAGGAAGCATTGGAAACTTGATAAGCTTCCTAGAGGATGGGGTCACGATGGCCCAGTACCAGCAGAGCCAGCACAACCTCATGC
ACATGCAGCCCCCGCCCCTGGAACCACCTAGCGTAGACATGATGTGCAGGGCGGCCAAGGCTTTGCTAGCCATGGCCAGAGTGGACGAAA
ACCGCTCGGAATTCCTTTTGCACGAGGGCCGGTTGCTGGATATCTCGATATCAGCTGTCCTGAACTCTCTGGTTGCATCTGTCATCTGTG
ATGTACTGTTTCAGATTGGGCAGTTATGACATAAGTGAGAAGGCAAGCATGTGTGAGTGAAGATTAGAGGGTCACATATAACTGGCTGTT
TTCTGTTCTTGTTTATCCAGCGTAGGAAGAAGGAAAAGAAAATCTTTGCTCCTCTGCCCCATTCACTATTTACCAATTGGGAATTAAAGA
AATAATTAATTTGAACAGTTATGAAATTAATATTTGCTGTCTGTGTGTATAAGTACATCCTTTGGGGTTTTTTTTTTCTCTTTTTTTTAA
CCAAAGTTGCTGTCTAGTGCATTCAAAGGTCACTTTTTGTTCTTCACAGATCTTTTTAATGTTCTTTCCCATGTTGTATTGCATTTTTGG
GGGAAGCAAATTGACTTTAAAGAAAAAAGTTGTGGCAAAAGATGCTAAGATGCGAAAATTTCACCACACTGAGTCAAAAAGGTGAAAAAT
TATCCATTTCCTATGCGTTTTACTCCTCAGAGAATGAAAAAAACTGCATCCCATCACCCAAAGTTCTGTGCAATAGAAATTTCTACAGAT
ACAGGTATAGGGGCTCAAGGAGGTATGTCGGTCAGTAGTCAAAACTATGAAATGATACTGGTTTCTCCACAGGAATATGGTTCCATTAGG
CTGGGAGCAAAAACAATGTTTTTTAAGATTGAGAATACATACCTGACAACGATCCGGAAACTGCTCCTCACCACTCCCGTCATGCCTGCT
GTCGGCGTTTGACCTTCCACGTGACAGTTCTTCACAATTCCTTTCATCATTTTTTAAATATTTTTTTTACTGCCTATGGGCTGTGATGTA
TATAGAAGTTGTACATTAAACATACCCTCATTTTTTTCTTTTCTTTTTTTTTTTTTTTTTTAGTACAAAGTTTTAGTTTCTTTTTCATGA
TGTGGTAACTACGAAGTGATGGTAGATTTAAATAATTTTTTATTTTTATTTTATATATTTTTTCATTAGGGCCATATCTCCAAAAAAAGA
AAGAAAAAATACAAAAAACAAAAACAAAAAAAAAAGAGGGTAATGTACAAGTTTCTGTATGTATAAAGTCATGCTCGATTTCAGGAGAGC
AGCTGATCACAATTTGCTTCATGAATCAAGGTGTGGAAATGGTTATATATGGATTGATTTAGAAAATGGTTACCAGTACAGTCAAAAAAG
AGAAAATGAAAAAAATACAACTAAAAGGAAGAAACACAACTTCAAAGATTTTTCAGTGATGAGAATCCACATTTGTATTTCAAGATAATG
TAGTTTAAAAAAAAAAAAAAGAAAAAAACTTGATGTAAATTCCTCCTTTTCCTCTGGCTTAATGAATATCATTTATTCAGTATAAAATCT

>38471_38471_4_IGF1R-ARID1B_IGF1R_chr15_99251336_ENST00000268035_ARID1B_chr6_157469758_ENST00000367148_length(amino acids)=1665AA_BP=214
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRV
AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKSNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR
PFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPY
SMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSIS
SPGWPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRE
LATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPT
PASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNS
SMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNM
QYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGP
TQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPF
LPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYD
DSTVATFNLSQLSGFLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEK
TESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRR
RPPPPLSSAGRKKEQEGKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLCTI
AHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNT
LVTLANISGQLDLSAYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYAT
LVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLA

--------------------------------------------------------------
>38471_38471_5_IGF1R-ARID1B_IGF1R_chr15_99251336_ENST00000558762_ARID1B_chr6_157469758_ENST00000275248_length(transcript)=6912nt_BP=1178nt
GGAGGGGGAGCCGCTCATTCATTTTGACTCCGCGTTTCTGCCCCTCGCCGGCCTCGCCTGTGACCCGGACTTCGGGGCGATCTTGCGAAC
TGCGTCGCGCCCTCCCGCGGCGGAAGCTCGGGCGTCCGGCCGCCTCCCGCGCGGCCAGGGCCGGGCTTGTTTTTCCTCGCCTAGGCAGAT
TTGGGCTTTGCCCCCTTTCTTTGCAGTTTTCCCCCCTTCCTGCCTCTCCGGGTTTGAAAATGGAGGCCGACGACGCCGACAGCCCGCCCC
GGCGCGCCTCGGGTTCCCGACTCCGCCGAGCCCTGGGCCGCTGCTGCCGGCGCTGAGGGGCCGCCCCGCGCCGCCCGCCCCGTCCGCGCA
CCCGGAGGGCCCCGGCGGCGCCGCCTTCGGAGTATTGTTTCCTTCGCCCTTGTTTTTGGAGGGGGAGCGAAGACTGAGTTTGAGACTTGT
TTCCTTTCATTTCCTTTTTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGAAAGGGGAATTTCATCCCAAATAAAAGGAAT
GAAGTCTGGCTCCGGAGGAGGGTCCCCGACCTCGCTGTGGGGGCTCCTGTTTCTCTCCGCCGCGCTCTCGCTCTGGCCGACGAGTGGAGA
AATCTGCGGGCCAGGCATCGACATCCGCAACGACTATCAGCAGCTGAAGCGCCTGGAGAACTGCACGGTGATCGAGGGCTACCTCCACAT
CCTGCTCATCTCCAAGGCCGAGGACTACCGCAGCTACCGCTTCCCCAAGCTCACGGTCATTACCGAGTACTTGCTGCTGTTCCGAGTGGC
TGGCCTCGAGAGCCTCGGAGACCTCTTCCCCAACCTCACGGTCATCCGCGGCTGGAAACTCTTCTACAACTACGCCCTGGTCATCTTCGA
GATGACCAATCTCAAGGATATTGGGCTTTACAACCTGAGGAACATTACTCGGGGGGCCATCAGGATTGAGAAAAATGCTGACCTCTGTTA
CCTCTCCACTGTGGACTGGTCCCTGATCCTGGATGCGGTGTCCAATAACTACATTGTGGGGAATAAGCCCCCAAAGGAATGTGGGGACCT
GTGTCCAGGGACCATGGAGGAGAAGCCGATGTGTGAGAAGACCACCATCAACAATGAGTACAACTACCGCTGCTGGACCACAAACCGCTG
CCAGAAAAGTAACTACTCCAGACCCCCAGCGTATAGTGGGGTGCCCAGTGCAAGCTACAGCGGCCCAGGGCCCGGTATGGGTATCAGTGC
CAACAACCAGATGCATGGACAAGGGCCAAGCCAGCCATGTGGTGCTGTGCCCCTGGGACGAATGCCATCAGCTGGGATGCAGAACAGACC
ATTTCCTGGAAATATGAGCAGCATGACCCCCAGTTCTCCTGGCATGTCTCAGCAGGGAGGGCCAGGAATGGGGCCGCCAATGCCAACTGT
GAACCGTAAGGCACAGGAGGCAGCCGCAGCAGTGATGCAGGCTGCTGCGAACTCAGCACAAAGCAGGCAAGGCAGTTTCCCCGGCATGAA
CCAGAGTGGACTTATGGCTTCCAGCTCTCCCTACAGCCAGCCCATGAACAACAGCTCTAGCCTGATGAACACGCAGGCGCCGCCCTACAG
CATGGCGCCCGCCATGGTGAACAGCTCGGCAGCATCTGTGGGTCTTGCAGATATGATGTCTCCTGGTGAATCCAAACTGCCCCTGCCTCT
CAAAGCAGACGGCAAAGAAGAAGGCACTCCACAGCCCGAGAGCAAGTCAAAGGATAGCTACAGCTCTCAGGGTATTTCTCAGCCCCCAAC
CCCAGGCAACCTGCCAGTCCCTTCCCCAATGTCCCCCAGCTCTGCTAGCATCTCCTCATTTCATGGAGATGAAAGTGATAGCATTAGCAG
CCCAGGCTGGCCAAAGACTCCATCAAGCCCTAAGTCCAGCTCCTCCACCACTACTGGGGAGAAGATCACGAAGGTGTACGAGCTGGGGAA
TGAGCCAGAGAGAAAGCTCTGGGTCGACCGATACCTCACCTTCATGGAAGAGAGAGGCTCTCCTGTCTCAAGTCTGCCTGCCGTGGGCAA
GAAGCCCCTGGACCTGTTCCGACTCTACGTCTGCGTCAAAGAGATCGGGGGTTTGGCCCAGGTTAATAAAAACAAGAAGTGGCGTGAGCT
GGCAACCAACCTAAACGTTGGCACCTCAAGCAGTGCAGCGAGCTCCCTGAAAAAGCAGTATATTCAGTACCTGTTTGCCTTTGAGTGCAA
GATCGAACGTGGGGAGGAGCCCCCGCCGGAAGTCTTCAGCACCGGGGACACCAAAAAGCAGCCCAAGCTCCAGCCGCCATCTCCTGCTAA
CTCGGGATCCTTGCAAGGCCCACAGACCCCCCAGTCAACTGGCAGCAATTCCATGGCAGAGGTTCCAGGTGACCTGAAGCCACCTACCCC
AGCCTCCACCCCTCACGGCCAGATGACTCCAATGCAAGGTGGAAGAAGCAGTACAATCAGTGTGCACGACCCATTCTCAGATGTGAGTGA
TTCATCCTTCCCGAAACGGAACTCCATGACTCCAAACGCCCCCTACCAGCAGGGCATGAGCATGCCCGATGTGATGGGCAGGATGCCCTA
TGAGCCCAACAAGGACCCCTTTGGGGGAATGAGAAAAGTGCCTGGAAGCAGCGAGCCCTTTATGACGCAAGGACAGATGCCCAACAGCAG
CATGCAGGACATGTACAACCAAAGTCCCTCCGGAGCAATGTCTAACCTGGGCATGGGGCAGCGCCAGCAGTTTCCCTATGGAGCCAGTTA
CGACCGAAGGCATGAACCTTATGGGCAGCAGTATCCAGGCCAAGGCCCTCCCTCGGGACAGCCGCCGTATGGAGGGCACCAGCCCGGCCT
GTACCCACAGCAGCCGAATTACAAACGCCATATGGACGGCATGTACGGGCCCCCAGCCAAGCGCCACGAGGGCGACATGTACAACATGCA
GTACAGCAGCCAGCAGCAGGAGATGTACAACCAGTATGGAGGCTCCTACTCGGGCCCGGACCGCAGGCCCATCCAGGGCCAGTACCCGTA
TCCCTACAGCAGGGAGAGGATGCAGGGCCCGGGGCAGATCCAGACACACGGAATCCCGCCTCAGATGATGGGCGGCCCGCTGCAGTCGTC
CTCCAGTGAGGGGCCTCAGCAGAATATGTGGGCAGCACGCAATGATATGCCTTATCCCTACCAGAACAGGCAGGGCCCTGGCGGCCCTAC
ACAGGCGCCCCCTTACCCAGGCATGAACCGCACAGACGATATGATGGTACCCGATCAGAGGATAAATCATGAGAGCCAGTGGCCTTCTCA
CGTCAGCCAGCGTCAGCCTTATATGTCGTCCTCAGCCTCCATGCAGCCCATCACACGCCCACCACAGCCGTCCTACCAGACGCCACCGTC
ACTGCCAAATCACATCTCCAGGGCGCCCAGCCCAGCGTCCTTCCAGCGCTCCCTGGAGAACCGCATGTCTCCAAGCAAGTCTCCTTTTCT
GCCGTCTATGAAGATGCAGAAGGTCATGCCCACGGTCCCCACATCCCAGGTCACCGGGCCACCACCCCAACCACCCCCAATCAGAAGGGA
GATCACCTTTCCTCCTGGCTCAGTAGAAGCATCACAACCAGTCTTGAAACAAAGGCGAAAGATTACCTCCAAAGATATCGTTACTCCTGA
GGCGTGGCGTGTGATGATGTCCCTTAAATCAGGTCTTTTGGCTGAGAGTACGTGGGCTTTGGACACTATTAATATTCTTCTGTATGATGA
CAGCACTGTTGCTACTTTCAATCTCTCCCAGTTGTCTGGATTTCTCGAACTTTTAGTCGAGTACTTTAGAAAATGCCTGATTGACATTTT
TGGAATTCTTATGGAATATGAAGTGGGAGACCCCAGCCAAAAAGCACTTGATCACAACGCAGCAAGGAAGGATGACAGCCAGTCCTTGGC
AGACGATTCTGGGAAAGAGGAGGAAGATGCTGAATGTATTGATGACGACGAGGAAGACGAGGAGGATGAGGAGGAAGACAGCGAGAAGAC
AGAAAGCGATGAAAAGAGCAGCATCGCTCTGACTGCCCCGGACGCCGCTGCAGACCCAAAGGAGAAGCCCAAGCAAGCCAGTAAGTTCGA
CAAGCTGCCAATAAAGATAGTCAAAAAGAACAACCTGTTTGTTGTTGACCGATCTGACAAGTTGGGGCGTGTGCAGGAGTTCAATAGTGG
CCTTCTGCACTGGCAGCTCGGCGGGGGTGACACCACCGAGCACATTCAGACTCACTTTGAGAGCAAGATGGAAATTCCTCCTCGCAGGCG
CCCACCTCCCCCCTTAAGCTCCGCAGGTAGAAAGAAAGAGCAAGAAGGCAAAGGCGACTCTGAAGAGCAGCAAGAGAAAAGCATCATAGC
AACCATCGATGACGTCCTCTCTGCTCGGCCAGGGGCATTGCCTGAAGACGCAAACCCTGGGCCCCAGACCGAAAGCAGTAAGTTTCCCTT
TGGTATCCAGCAAGCCAAAAGTCACCGGAACATCAAGCTGCTGGAGGACGAGCCCAGGAGCCGAGACGAGACTCCTCTGTGTACCATCGC
GCACTGGCAGGACTCGCTGGCTAAGCGATGCATCTGTGTGTCCAATATTGTCCGTAGCTTGTCATTCGTGCCTGGCAATGATGCCGAAAT
GTCCAAACATCCAGGCCTGGTGCTGATCCTGGGGAAGCTGATTCTTCTTCACCACGAGCATCCAGAGAGAAAGCGAGCACCGCAGACCTA
TGAGAAAGAGGAGGATGAGGACAAGGGGGTGGCCTGCAGCAAAGATGAGTGGTGGTGGGACTGCCTCGAGGTCTTGAGGGATAACACGTT
GGTCACGTTGGCCAACATTTCCGGGCAGCTAGACTTGTCTGCTTACACGGAAAGCATCTGCTTGCCAATTTTGGATGGCTTGCTGCACTG
GATGGTGTGCCCGTCTGCAGAGGCACAAGATCCCTTTCCAACTGTGGGACCCAACTCGGTCCTGTCGCCTCAGAGACTTGTGCTGGAGAC
CCTCTGTAAACTCAGTATCCAGGACAATAATGTGGACCTGATCTTGGCCACTCCTCCATTTAGTCGTCAGGAGAAATTCTATGCTACATT
AGTTAGGTACGTTGGGGATCGCAAAAACCCAGTCTGTCGAGAAATGTCCATGGCGCTTTTATCGAACCTTGCCCAAGGGGACGCACTAGC
AGCAAGGGCCATAGCTGTGCAGAAAGGAAGCATTGGAAACTTGATAAGCTTCCTAGAGGATGGGGTCACGATGGCCCAGTACCAGCAGAG
CCAGCACAACCTCATGCACATGCAGCCCCCGCCCCTGGAACCACCTAGCGTAGACATGATGTGCAGGGCGGCCAAGGCTTTGCTAGCCAT
GGCCAGAGTGGACGAAAACCGCTCGGAATTCCTTTTGCACGAGGGCCGGTTGCTGGATATCTCGATATCAGCTGTCCTGAACTCTCTGGT
TGCATCTGTCATCTGTGATGTACTGTTTCAGATTGGGCAGTTATGACATAAGTGAGAAGGCAAGCATGTGTGAGTGAAGATTAGAGGGTC
ACATATAACTGGCTGTTTTCTGTTCTTGTTTATCCAGCGTAGGAAGAAGGAAAAGAAAATCTTTGCTCCTCTGCCCCATTCACTATTTAC
CAATTGGGAATTAAAGAAATAATTAATTTGAACAGTTATGAAATTAATATTTGCTGTCTGTGTGTATAAGTACATCCTTTGGGGTTTTTT
TTTTCTCTTTTTTTTAACCAAAGTTGCTGTCTAGTGCATTCAAAGGTCACTTTTTGTTCTTCACAGATCTTTTTAATGTTCTTTCCCATG
TTGTATTGCATTTTTGGGGGAAGCAAATTGACTTTAAAGAAAAAAGTTGTGGCAAAAGATGCTAAGATGCGAAAATTTCACCACACTGAG
TCAAAAAGGTGAAAAATTATCCATTTCCTATGCGTTTTACTCCTCAGAGAATGAAAAAAACTGCATCCCATCACCCAAAGTTCTGTGCAA
TAGAAATTTCTACAGATACAGGTATAGGGGCTCAAGGAGGTATGTCGGTCAGTAGTCAAAACTATGAAATGATACTGGTTTCTCCACAGG
AATATGGTTCCATTAGGCTGGGAGCAAAAACAATGTTTTTTAAGATTGAGAATACATACCTGACAACGATCCGGAAACTGCTCCTCACCA
CTCCCGTCATGCCTGCTGTCGGCGTTTGACCTTCCACGTGACAGTTCTTCACAATTCCTTTCATCATTTTTTAAATATTTTTTTTACTGC
CTATGGGCTGTGATGTATATAGAAGTTGTACATTAAACATACCCTCATTTTTTTCTTTTCTTTTTTTTTTTTTTTTTTAGTACAAAGTTT
TAGTTTCTTTTTCATGATGTGGTAACTACGAAGTGATGGTAGATTTAAATAATTTTTTATTTTTATTTTATATATTTTTTCATTAGGGCC
ATATCTCCAAAAAAAGAAAGAAAAAATACAAAAAACAAAAACAAAAAAAAAAGAGGGTAATGTACAAGTTTCTGTATGTATAAAGTCATG
CTCGATTTCAGGAGAGCAGCTGATCACAATTTGCTTCATGAATCAAGGTGTGGAAATGGTTATATATGGATTGATTTAGAAAATGGTTAC
CAGTACAGTCAAAAAAGAGAAAATGAAAAAAATACAACTAAAAGGAAGAAACACAACTTCAAAGATTTTTCAGTGATGAGAATCCACATT
TGTATTTCAAGATAATGTAGTTTAAAAAAAAAAAAAAGAAAAAAACTTGATGTAAATTCCTCCTTTTCCTCTGGCTTAATGAATATCATT

>38471_38471_5_IGF1R-ARID1B_IGF1R_chr15_99251336_ENST00000558762_ARID1B_chr6_157469758_ENST00000275248_length(amino acids)=1665AA_BP=214
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRV
AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKSNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR
PFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPY
SMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSIS
SPGWPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRE
LATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPT
PASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNS
SMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNM
QYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGP
TQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPF
LPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYD
DSTVATFNLSQLSGFLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEK
TESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRR
RPPPPLSSAGRKKEQEGKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLCTI
AHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNT
LVTLANISGQLDLSAYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYAT
LVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLA

--------------------------------------------------------------
>38471_38471_6_IGF1R-ARID1B_IGF1R_chr15_99251336_ENST00000558762_ARID1B_chr6_157469758_ENST00000346085_length(transcript)=8265nt_BP=1178nt
GGAGGGGGAGCCGCTCATTCATTTTGACTCCGCGTTTCTGCCCCTCGCCGGCCTCGCCTGTGACCCGGACTTCGGGGCGATCTTGCGAAC
TGCGTCGCGCCCTCCCGCGGCGGAAGCTCGGGCGTCCGGCCGCCTCCCGCGCGGCCAGGGCCGGGCTTGTTTTTCCTCGCCTAGGCAGAT
TTGGGCTTTGCCCCCTTTCTTTGCAGTTTTCCCCCCTTCCTGCCTCTCCGGGTTTGAAAATGGAGGCCGACGACGCCGACAGCCCGCCCC
GGCGCGCCTCGGGTTCCCGACTCCGCCGAGCCCTGGGCCGCTGCTGCCGGCGCTGAGGGGCCGCCCCGCGCCGCCCGCCCCGTCCGCGCA
CCCGGAGGGCCCCGGCGGCGCCGCCTTCGGAGTATTGTTTCCTTCGCCCTTGTTTTTGGAGGGGGAGCGAAGACTGAGTTTGAGACTTGT
TTCCTTTCATTTCCTTTTTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGAAAGGGGAATTTCATCCCAAATAAAAGGAAT
GAAGTCTGGCTCCGGAGGAGGGTCCCCGACCTCGCTGTGGGGGCTCCTGTTTCTCTCCGCCGCGCTCTCGCTCTGGCCGACGAGTGGAGA
AATCTGCGGGCCAGGCATCGACATCCGCAACGACTATCAGCAGCTGAAGCGCCTGGAGAACTGCACGGTGATCGAGGGCTACCTCCACAT
CCTGCTCATCTCCAAGGCCGAGGACTACCGCAGCTACCGCTTCCCCAAGCTCACGGTCATTACCGAGTACTTGCTGCTGTTCCGAGTGGC
TGGCCTCGAGAGCCTCGGAGACCTCTTCCCCAACCTCACGGTCATCCGCGGCTGGAAACTCTTCTACAACTACGCCCTGGTCATCTTCGA
GATGACCAATCTCAAGGATATTGGGCTTTACAACCTGAGGAACATTACTCGGGGGGCCATCAGGATTGAGAAAAATGCTGACCTCTGTTA
CCTCTCCACTGTGGACTGGTCCCTGATCCTGGATGCGGTGTCCAATAACTACATTGTGGGGAATAAGCCCCCAAAGGAATGTGGGGACCT
GTGTCCAGGGACCATGGAGGAGAAGCCGATGTGTGAGAAGACCACCATCAACAATGAGTACAACTACCGCTGCTGGACCACAAACCGCTG
CCAGAAAAGTAACTACTCCAGACCCCCAGCGTATAGTGGGGTGCCCAGTGCAAGCTACAGCGGCCCAGGGCCCGGTATGGGTATCAGTGC
CAACAACCAGATGCATGGACAAGGGCCAAGCCAGCCATGTGGTGCTGTGCCCCTGGGACGAATGCCATCAGCTGGGATGCAGAACAGACC
ATTTCCTGGAAATATGAGCAGCATGACCCCCAGTTCTCCTGGCATGTCTCAGCAGGGAGGGCCAGGAATGGGGCCGCCAATGCCAACTGT
GAACCGTAAGGCACAGGAGGCAGCCGCAGCAGTGATGCAGGCTGCTGCGAACTCAGCACAAAGCAGGCAAGGCAGTTTCCCCGGCATGAA
CCAGAGTGGACTTATGGCTTCCAGCTCTCCCTACAGCCAGCCCATGAACAACAGCTCTAGCCTGATGAACACGCAGGCGCCGCCCTACAG
CATGGCGCCCGCCATGGTGAACAGCTCGGCAGCATCTGTGGGTCTTGCAGATATGATGTCTCCTGGTGAATCCAAACTGCCCCTGCCTCT
CAAAGCAGACGGCAAAGAAGAAGGCACTCCACAGCCCGAGAGCAAGTCAAAGAAGTCCAGCTCCTCCACCACTACTGGGGAGAAGATCAC
GAAGGTGTACGAGCTGGGGAATGAGCCAGAGAGAAAGCTCTGGGTCGACCGATACCTCACCTTCATGGAAGAGAGAGGCTCTCCTGTCTC
AAGTCTGCCTGCCGTGGGCAAGAAGCCCCTGGACCTGTTCCGACTCTACGTCTGCGTCAAAGAGATCGGGGGTTTGGCCCAGGTTAATAA
AAACAAGAAGTGGCGTGAGCTGGCAACCAACCTAAACGTTGGCACCTCAAGCAGTGCAGCGAGCTCCCTGAAAAAGCAGTATATTCAGTA
CCTGTTTGCCTTTGAGTGCAAGATCGAACGTGGGGAGGAGCCCCCGCCGGAAGTCTTCAGCACCGGGGACACCAAAAAGCAGCCCAAGCT
CCAGCCGCCATCTCCTGCTAACTCGGGATCCTTGCAAGGCCCACAGACCCCCCAGTCAACTGGCAGCAATTCCATGGCAGAGGTTCCAGG
TGACCTGAAGCCACCTACCCCAGCCTCCACCCCTCACGGCCAGATGACTCCAATGCAAGGTGGAAGAAGCAGTACAATCAGTGTGCACGA
CCCATTCTCAGATGTGAGTGATTCATCCTTCCCGAAACGGAACTCCATGACTCCAAACGCCCCCTACCAGCAGGGCATGAGCATGCCCGA
TGTGATGGGCAGGATGCCCTATGAGCCCAACAAGGACCCCTTTGGGGGAATGAGAAAAGTGCCTGGAAGCAGCGAGCCCTTTATGACGCA
AGGACAGATGCCCAACAGCAGCATGCAGGACATGTACAACCAAAGTCCCTCCGGAGCAATGTCTAACCTGGGCATGGGGCAGCGCCAGCA
GTTTCCCTATGGAGCCAGTTACGACCGAAGGCATGAACCTTATGGGCAGCAGTATCCAGGCCAAGGCCCTCCCTCGGGACAGCCGCCGTA
TGGAGGGCACCAGCCCGGCCTGTACCCACAGCAGCCGAATTACAAACGCCATATGGACGGCATGTACGGGCCCCCAGCCAAGCGCCACGA
GGGCGACATGTACAACATGCAGTACAGCAGCCAGCAGCAGGAGATGTACAACCAGTATGGAGGCTCCTACTCGGGCCCGGACCGCAGGCC
CATCCAGGGCCAGTACCCGTATCCCTACAGCAGGGAGAGGATGCAGGGCCCGGGGCAGATCCAGACACACGGAATCCCGCCTCAGATGAT
GGGCGGCCCGCTGCAGTCGTCCTCCAGTGAGGGGCCTCAGCAGAATATGTGGGCAGCACGCAATGATATGCCTTATCCCTACCAGAACAG
GCAGGGCCCTGGCGGCCCTACACAGGCGCCCCCTTACCCAGGCATGAACCGCACAGACGATATGATGGTACCCGATCAGAGGATAAATCA
TGAGAGCCAGTGGCCTTCTCACGTCAGCCAGCGTCAGCCTTATATGTCGTCCTCAGCCTCCATGCAGCCCATCACACGCCCACCACAGCC
GTCCTACCAGACGCCACCGTCACTGCCAAATCACATCTCCAGGGCGCCCAGCCCAGCGTCCTTCCAGCGCTCCCTGGAGAACCGCATGTC
TCCAAGCAAGTCTCCTTTTCTGCCGTCTATGAAGATGCAGAAGGTCATGCCCACGGTCCCCACATCCCAGGTCACCGGGCCACCACCCCA
ACCACCCCCAATCAGAAGGGAGATCACCTTTCCTCCTGGCTCAGTAGAAGCATCACAACCAGTCTTGAAACAAAGGCGAAAGATTACCTC
CAAAGATATCGTTACTCCTGAGGCGTGGCGTGTGATGATGTCCCTTAAATCAGGTCTTTTGGCTGAGAGTACGTGGGCTTTGGACACTAT
TAATATTCTTCTGTATGATGACAGCACTGTTGCTACTTTCAATCTCTCCCAGTTGTCTGGATTTCTCGAACTTTTAGTCGAGTACTTTAG
AAAATGCCTGATTGACATTTTTGGAATTCTTATGGAATATGAAGTGGGAGACCCCAGCCAAAAAGCACTTGATCACAACGCAGCAAGGAA
GGATGACAGCCAGTCCTTGGCAGACGATTCTGGGAAAGAGGAGGAAGATGCTGAATGTATTGATGACGACGAGGAAGACGAGGAGGATGA
GGAGGAAGACAGCGAGAAGACAGAAAGCGATGAAAAGAGCAGCATCGCTCTGACTGCCCCGGACGCCGCTGCAGACCCAAAGGAGAAGCC
CAAGCAAGCCAGTAAGTTCGACAAGCTGCCAATAAAGATAGTCAAAAAGAACAACCTGTTTGTTGTTGACCGATCTGACAAGTTGGGGCG
TGTGCAGGAGTTCAATAGTGGCCTTCTGCACTGGCAGCTCGGCGGGGGTGACACCACCGAGCACATTCAGACTCACTTTGAGAGCAAGAT
GGAAATTCCTCCTCGCAGGCGCCCACCTCCCCCCTTAAGCTCCGCAGGTAGAAAGAAAGAGCAAGAAGGCAAAGGCGACTCTGAAGAGCA
GCAAGAGAAAAGCATCATAGCAACCATCGATGACGTCCTCTCTGCTCGGCCAGGGGCATTGCCTGAAGACGCAAACCCTGGGCCCCAGAC
CGAAAGCAGTAAGTTTCCCTTTGGTATCCAGCAAGCCAAAAGTCACCGGAACATCAAGCTGCTGGAGGACGAGCCCAGGAGCCGAGACGA
GACTCCTCTGTGTACCATCGCGCACTGGCAGGACTCGCTGGCTAAGCGATGCATCTGTGTGTCCAATATTGTCCGTAGCTTGTCATTCGT
GCCTGGCAATGATGCCGAAATGTCCAAACATCCAGGCCTGGTGCTGATCCTGGGGAAGCTGATTCTTCTTCACCACGAGCATCCAGAGAG
AAAGCGAGCACCGCAGACCTATGAGAAAGAGGAGGATGAGGACAAGGGGGTGGCCTGCAGCAAAGATGAGTGGTGGTGGGACTGCCTCGA
GGTCTTGAGGGATAACACGTTGGTCACGTTGGCCAACATTTCCGGGCAGCTAGACTTGTCTGCTTACACGGAAAGCATCTGCTTGCCAAT
TTTGGATGGCTTGCTGCACTGGATGGTGTGCCCGTCTGCAGAGGCACAAGATCCCTTTCCAACTGTGGGACCCAACTCGGTCCTGTCGCC
TCAGAGACTTGTGCTGGAGACCCTCTGTAAACTCAGTATCCAGGACAATAATGTGGACCTGATCTTGGCCACTCCTCCATTTAGTCGTCA
GGAGAAATTCTATGCTACATTAGTTAGGTACGTTGGGGATCGCAAAAACCCAGTCTGTCGAGAAATGTCCATGGCGCTTTTATCGAACCT
TGCCCAAGGGGACGCACTAGCAGCAAGGGCCATAGCTGTGCAGAAAGGAAGCATTGGAAACTTGATAAGCTTCCTAGAGGATGGGGTCAC
GATGGCCCAGTACCAGCAGAGCCAGCACAACCTCATGCACATGCAGCCCCCGCCCCTGGAACCACCTAGCGTAGACATGATGTGCAGGGC
GGCCAAGGCTTTGCTAGCCATGGCCAGAGTGGACGAAAACCGCTCGGAATTCCTTTTGCACGAGGGCCGGTTGCTGGATATCTCGATATC
AGCTGTCCTGAACTCTCTGGTTGCATCTGTCATCTGTGATGTACTGTTTCAGATTGGGCAGTTATGACATAAGTGAGAAGGCAAGCATGT
GTGAGTGAAGATTAGAGGGTCACATATAACTGGCTGTTTTCTGTTCTTGTTTATCCAGCGTAGGAAGAAGGAAAAGAAAATCTTTGCTCC
TCTGCCCCATTCACTATTTACCAATTGGGAATTAAAGAAATAATTAATTTGAACAGTTATGAAATTAATATTTGCTGTCTGTGTGTATAA
GTACATCCTTTGGGGTTTTTTTTTTCTCTTTTTTTTAACCAAAGTTGCTGTCTAGTGCATTCAAAGGTCACTTTTTGTTCTTCACAGATC
TTTTTAATGTTCTTTCCCATGTTGTATTGCATTTTTGGGGGAAGCAAATTGACTTTAAAGAAAAAAGTTGTGGCAAAAGATGCTAAGATG
CGAAAATTTCACCACACTGAGTCAAAAAGGTGAAAAATTATCCATTTCCTATGCGTTTTACTCCTCAGAGAATGAAAAAAACTGCATCCC
ATCACCCAAAGTTCTGTGCAATAGAAATTTCTACAGATACAGGTATAGGGGCTCAAGGAGGTATGTCGGTCAGTAGTCAAAACTATGAAA
TGATACTGGTTTCTCCACAGGAATATGGTTCCATTAGGCTGGGAGCAAAAACAATGTTTTTTAAGATTGAGAATACATACCTGACAACGA
TCCGGAAACTGCTCCTCACCACTCCCGTCATGCCTGCTGTCGGCGTTTGACCTTCCACGTGACAGTTCTTCACAATTCCTTTCATCATTT
TTTAAATATTTTTTTTACTGCCTATGGGCTGTGATGTATATAGAAGTTGTACATTAAACATACCCTCATTTTTTTCTTTTCTTTTTTTTT
TTTTTTTTTAGTACAAAGTTTTAGTTTCTTTTTCATGATGTGGTAACTACGAAGTGATGGTAGATTTAAATAATTTTTTATTTTTATTTT
ATATATTTTTTCATTAGGGCCATATCTCCAAAAAAAGAAAGAAAAAATACAAAAAACAAAAACAAAAAAAAAAGAGGGTAATGTACAAGT
TTCTGTATGTATAAAGTCATGCTCGATTTCAGGAGAGCAGCTGATCACAATTTGCTTCATGAATCAAGGTGTGGAAATGGTTATATATGG
ATTGATTTAGAAAATGGTTACCAGTACAGTCAAAAAAGAGAAAATGAAAAAAATACAACTAAAAGGAAGAAACACAACTTCAAAGATTTT
TCAGTGATGAGAATCCACATTTGTATTTCAAGATAATGTAGTTTAAAAAAAAAAAAAAGAAAAAAACTTGATGTAAATTCCTCCTTTTCC
TCTGGCTTAATGAATATCATTTATTCAGTATAAAATCTTTATATGTTCCACATGTTAAGAATAAATGTACATTAAATCTTGTTAAGCACT
GTGATGGGTGTTCTTGAATACTGTTCTAGTTTCCTTAAAGTGGTTTCCTAGTAATCAAGTTATTTACAAGAAATAGGGGAATGCAGCAGT
GTATTCACATTATAAAACCCTACATTTGGAAGAGACCTTTAGGGGTTACCTACTTTAGAGTGGGGAGCAACAGTTTGATTTTCTCAAATT
ACTTAGCTAATTAGTCTTTCTTTGAAGCAATTAACTCTAACGACATTGAGGTATGATCATTTTCAGTATTTATGGGAGGTGGCTGCTGAC
CCACTTGAGGTGAGATCTCAGAAGCTTAACTGGCCTGAAAATGTAACATTCTGCCTTTTACTAACTCCATCTTAGTTTAATCAAAGTTCA
ATCTATTCCTTGTTTCTTCTGTGTGCCTCAGAGTTATTTTGCATTTAGTTTACTCCACCGTGTATAATATTTATACTGTGCAATGTTAAA
AAAGAATCTGTTATATTGTATGTGGTGTACATAGTGCAAAGTGATGATTTCTATTTCAGGGCATATTATGGTTCTCATATTCCTTCCTAC
CTGGTGCACAGTAGCTTTTTAATACTAGTCACTTCTAATTTAAACTTTCTCTTCCTGGGTCATTGACTGTTACTGTGTAATAATCGATTT
CTTTGAAACTGCTGCATAATTATGCTGTTAGTGGACCTCTACCTCTTCTCTTCCCTCTCCCAATCACAGTATACTCAGAATCCCCAGCCC
CTCGCATACATTGTGTCGGTTCACATTACTCACAGTAATATATGGAAGAGTTAGACAAGAACATGCAGTTACAGTCATTGTGAGACGTGA
CTCTCCAGTGTCACGAGGAAAAAAATCATCTTTTCTGCAAACAGTCTCTCATCTGTCAACTCCCACATTACTGAGTCAAACAGTCTTCTT
ACATAACAATGCAACCAAATATATGTTGAATTAAAGACCCATTTATAATTCTGCTTTAAATACATCTGCTTGCTAAGAACAGATTTCAGT
GCTCCAAGCTTCAAATATGGAGATTTGTAAGAGGGAATTCAATATTATTCTAATTTCTCTCTTACAGAGTACAAATAAAAGGTGTATACA
AACTCCGAACATATCCAGTATTCCAATTCCTTTGTCAATCAGAAGAGTAAAATAATTAACAAAAGACTGTTGTTATGGTTTGCATTGTAA
CCGATACGCAGAGTCTGACCGTTGGGCAACAAGTTTTTCTATCCTGATGCGCAACACAGTCTCTAGAGACTAATCCAGGAAGACTTTAGC
CTCCTTTCCATATTCTCACCCCCGAATCAAGATTTACAGAAGCCCACGAAGAATTTACAGCCTGCTTGAGATCATCTTGCCTATAAACTG
AGTTATTGCTTTGTCCTAAAAATTAGTCGGTTTTTTTTTTTCTATGAGGCTTTTCAGAAATTTACAGGATGCCCAGACTTTACATGTGTA

>38471_38471_6_IGF1R-ARID1B_IGF1R_chr15_99251336_ENST00000558762_ARID1B_chr6_157469758_ENST00000346085_length(amino acids)=1612AA_BP=214
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRV
AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKSNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR
PFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPY
SMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPV
SSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPK
LQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMP
DVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPP
YGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQM
MGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQ
PSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKIT
SKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAAR
KDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLG
RVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQEGKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQ
TESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPE
RKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLS
PQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGV

--------------------------------------------------------------
>38471_38471_7_IGF1R-ARID1B_IGF1R_chr15_99251336_ENST00000558762_ARID1B_chr6_157469758_ENST00000350026_length(transcript)=6636nt_BP=1178nt
GGAGGGGGAGCCGCTCATTCATTTTGACTCCGCGTTTCTGCCCCTCGCCGGCCTCGCCTGTGACCCGGACTTCGGGGCGATCTTGCGAAC
TGCGTCGCGCCCTCCCGCGGCGGAAGCTCGGGCGTCCGGCCGCCTCCCGCGCGGCCAGGGCCGGGCTTGTTTTTCCTCGCCTAGGCAGAT
TTGGGCTTTGCCCCCTTTCTTTGCAGTTTTCCCCCCTTCCTGCCTCTCCGGGTTTGAAAATGGAGGCCGACGACGCCGACAGCCCGCCCC
GGCGCGCCTCGGGTTCCCGACTCCGCCGAGCCCTGGGCCGCTGCTGCCGGCGCTGAGGGGCCGCCCCGCGCCGCCCGCCCCGTCCGCGCA
CCCGGAGGGCCCCGGCGGCGCCGCCTTCGGAGTATTGTTTCCTTCGCCCTTGTTTTTGGAGGGGGAGCGAAGACTGAGTTTGAGACTTGT
TTCCTTTCATTTCCTTTTTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGAAAGGGGAATTTCATCCCAAATAAAAGGAAT
GAAGTCTGGCTCCGGAGGAGGGTCCCCGACCTCGCTGTGGGGGCTCCTGTTTCTCTCCGCCGCGCTCTCGCTCTGGCCGACGAGTGGAGA
AATCTGCGGGCCAGGCATCGACATCCGCAACGACTATCAGCAGCTGAAGCGCCTGGAGAACTGCACGGTGATCGAGGGCTACCTCCACAT
CCTGCTCATCTCCAAGGCCGAGGACTACCGCAGCTACCGCTTCCCCAAGCTCACGGTCATTACCGAGTACTTGCTGCTGTTCCGAGTGGC
TGGCCTCGAGAGCCTCGGAGACCTCTTCCCCAACCTCACGGTCATCCGCGGCTGGAAACTCTTCTACAACTACGCCCTGGTCATCTTCGA
GATGACCAATCTCAAGGATATTGGGCTTTACAACCTGAGGAACATTACTCGGGGGGCCATCAGGATTGAGAAAAATGCTGACCTCTGTTA
CCTCTCCACTGTGGACTGGTCCCTGATCCTGGATGCGGTGTCCAATAACTACATTGTGGGGAATAAGCCCCCAAAGGAATGTGGGGACCT
GTGTCCAGGGACCATGGAGGAGAAGCCGATGTGTGAGAAGACCACCATCAACAATGAGTACAACTACCGCTGCTGGACCACAAACCGCTG
CCAGAAAAGTAACTACTCCAGACCCCCAGCGTATAGTGGGGTGCCCAGTGCAAGCTACAGCGGCCCAGGGCCCGGTATGGGTATCAGTGC
CAACAACCAGATGCATGGACAAGGGCCAAGCCAGCCATGTGGTGCTGTGCCCCTGGGACGAATGCCATCAGCTGGGATGCAGAACAGACC
ATTTCCTGGAAATATGAGCAGCATGACCCCCAGTTCTCCTGGCATGTCTCAGCAGGGAGGGCCAGGAATGGGGCCGCCAATGCCAACTGT
GAACCGTAAGGCACAGGAGGCAGCCGCAGCAGTGATGCAGGCTGCTGCGAACTCAGCACAAAGCAGGCAAGGCAGTTTCCCCGGCATGAA
CCAGAGTGGACTTATGGCTTCCAGCTCTCCCTACAGCCAGCCCATGAACAACAGCTCTAGCCTGATGAACACGCAGGCGCCGCCCTACAG
CATGGCGCCCGCCATGGTGAACAGCTCGGCAGCATCTGTGGGTCTTGCAGATATGATGTCTCCTGGTGAATCCAAACTGCCCCTGCCTCT
CAAAGCAGACGGCAAAGAAGAAGGCACTCCACAGCCCGAGAGCAAGTCAAAGAAGTCCAGCTCCTCCACCACTACTGGGGAGAAGATCAC
GAAGGTGTACGAGCTGGGGAATGAGCCAGAGAGAAAGCTCTGGGTCGACCGATACCTCACCTTCATGGAAGAGAGAGGCTCTCCTGTCTC
AAGTCTGCCTGCCGTGGGCAAGAAGCCCCTGGACCTGTTCCGACTCTACGTCTGCGTCAAAGAGATCGGGGGTTTGGCCCAGGTTAATAA
AAACAAGAAGTGGCGTGAGCTGGCAACCAACCTAAACGTTGGCACCTCAAGCAGTGCAGCGAGCTCCCTGAAAAAGCAGTATATTCAGTA
CCTGTTTGCCTTTGAGTGCAAGATCGAACGTGGGGAGGAGCCCCCGCCGGAAGTCTTCAGCACCGGGGACACCAAAAAGCAGCCCAAGCT
CCAGCCGCCATCTCCTGCTAACTCGGGATCCTTGCAAGGCCCACAGACCCCCCAGTCAACTGGCAGCAATTCCATGGCAGAGGTTCCAGG
TGACCTGAAGCCACCTACCCCAGCCTCCACCCCTCACGGCCAGATGACTCCAATGCAAGGTGGAAGAAGCAGTACAATCAGTGTGCACGA
CCCATTCTCAGATGTGAGTGATTCATCCTTCCCGAAACGGAACTCCATGACTCCAAACGCCCCCTACCAGCAGGGCATGAGCATGCCCGA
TGTGATGGGCAGGATGCCCTATGAGCCCAACAAGGACCCCTTTGGGGGAATGAGAAAAGTGCCTGGAAGCAGCGAGCCCTTTATGACGCA
AGGACAGATGCCCAACAGCAGCATGCAGGACATGTACAACCAAAGTCCCTCCGGAGCAATGTCTAACCTGGGCATGGGGCAGCGCCAGCA
GTTTCCCTATGGAGCCAGTTACGACCGAAGGCATGAACCTTATGGGCAGCAGTATCCAGGCCAAGGCCCTCCCTCGGGACAGCCGCCGTA
TGGAGGGCACCAGCCCGGCCTGTACCCACAGCAGCCGAATTACAAACGCCATATGGACGGCATGTACGGGCCCCCAGCCAAGCGCCACGA
GGGCGACATGTACAACATGCAGTACAGCAGCCAGCAGCAGGAGATGTACAACCAGTATGGAGGCTCCTACTCGGGCCCGGACCGCAGGCC
CATCCAGGGCCAGTACCCGTATCCCTACAGCAGGGAGAGGATGCAGGGCCCGGGGCAGATCCAGACACACGGAATCCCGCCTCAGATGAT
GGGCGGCCCGCTGCAGTCGTCCTCCAGTGAGGGGCCTCAGCAGAATATGTGGGCAGCACGCAATGATATGCCTTATCCCTACCAGAACAG
GCAGGGCCCTGGCGGCCCTACACAGGCGCCCCCTTACCCAGGCATGAACCGCACAGACGATATGATGGTACCCGATCAGAGGATAAATCA
TGAGAGCCAGTGGCCTTCTCACGTCAGCCAGCGTCAGCCTTATATGTCGTCCTCAGCCTCCATGCAGCCCATCACACGCCCACCACAGCC
GTCCTACCAGACGCCACCGTCACTGCCAAATCACATCTCCAGGGCGCCCAGCCCAGCGTCCTTCCAGCGCTCCCTGGAGAACCGCATGTC
TCCAAGCAAGTCTCCTTTTCTGCCGTCTATGAAGATGCAGAAGGTCATGCCCACGGTCCCCACATCCCAGGTCACCGGGCCACCACCCCA
ACCACCCCCAATCAGAAGGGAGATCACCTTTCCTCCTGGCTCAGTAGAAGCATCACAACCAGTCTTGAAACAAAGGCGAAAGATTACCTC
CAAAGATATCGTTACTCCTGAGGCGTGGCGTGTGATGATGTCCCTTAAATCAGGTCTTTTGGCTGAGAGTACGTGGGCTTTGGACACTAT
TAATATTCTTCTGTATGATGACAGCACTGTTGCTACTTTCAATCTCTCCCAGTTGTCTGGATTTCTCGAACTTTTAGTCGAGTACTTTAG
AAAATGCCTGATTGACATTTTTGGAATTCTTATGGAATATGAAGTGGGAGACCCCAGCCAAAAAGCACTTGATCACAACGCAGCAAGGAA
GGATGACAGCCAGTCCTTGGCAGACGATTCTGGGAAAGAGGAGGAAGATGCTGAATGTATTGATGACGACGAGGAAGACGAGGAGGATGA
GGAGGAAGACAGCGAGAAGACAGAAAGCGATGAAAAGAGCAGCATCGCTCTGACTGCCCCGGACGCCGCTGCAGACCCAAAGGAGAAGCC
CAAGCAAGCCAGTAAGTTCGACAAGCTGCCAATAAAGATAGTCAAAAAGAACAACCTGTTTGTTGTTGACCGATCTGACAAGTTGGGGCG
TGTGCAGGAGTTCAATAGTGGCCTTCTGCACTGGCAGCTCGGCGGGGGTGACACCACCGAGCACATTCAGACTCACTTTGAGAGCAAGAT
GGAAATTCCTCCTCGCAGGCGCCCACCTCCCCCCTTAAGCTCCGCAGGTAGAAAGAAAGAGCAAGAAGGCAAAGGCGACTCTGAAGAGCA
GCAAGAGAAAAGCATCATAGCAACCATCGATGACGTCCTCTCTGCTCGGCCAGGGGCATTGCCTGAAGACGCAAACCCTGGGCCCCAGAC
CGAAAGCAGTAAGTTTCCCTTTGGTATCCAGCAAGCCAAAAGTCACCGGAACATCAAGCTGCTGGAGGACGAGCCCAGGAGCCGAGACGA
GACTCCTCTGTGTACCATCGCGCACTGGCAGGACTCGCTGGCTAAGCGATGCATCTGTGTGTCCAATATTGTCCGTAGCTTGTCATTCGT
GCCTGGCAATGATGCCGAAATGTCCAAACATCCAGGCCTGGTGCTGATCCTGGGGAAGCTGATTCTTCTTCACCACGAGCATCCAGAGAG
AAAGCGAGCACCGCAGACCTATGAGAAAGAGGAGGATGAGGACAAGGGGGTGGCCTGCAGCAAAGATGAGTGGTGGTGGGACTGCCTCGA
GGTCTTGAGGGATAACACGTTGGTCACGTTGGCCAACATTTCCGGGCAGCTAGACTTGTCTGCTTACACGGAAAGCATCTGCTTGCCAAT
TTTGGATGGCTTGCTGCACTGGATGGTGTGCCCGTCTGCAGAGGCACAAGATCCCTTTCCAACTGTGGGACCCAACTCGGTCCTGTCGCC
TCAGAGACTTGTGCTGGAGACCCTCTGTAAACTCAGTATCCAGGACAATAATGTGGACCTGATCTTGGCCACTCCTCCATTTAGTCGTCA
GGAGAAATTCTATGCTACATTAGTTAGGTACGTTGGGGATCGCAAAAACCCAGTCTGTCGAGAAATGTCCATGGCGCTTTTATCGAACCT
TGCCCAAGGGGACGCACTAGCAGCAAGGGCCATAGCTGTGCAGAAAGGAAGCATTGGAAACTTGATAAGCTTCCTAGAGGATGGGGTCAC
GATGGCCCAGTACCAGCAGAGCCAGCACAACCTCATGCACATGCAGCCCCCGCCCCTGGAACCACCTAGCGTAGACATGATGTGCAGGGC
GGCCAAGGCTTTGCTAGCCATGGCCAGAGTGGACGAAAACCGCTCGGAATTCCTTTTGCACGAGGGCCGGTTGCTGGATATCTCGATATC
AGCTGTCCTGAACTCTCTGGTTGCATCTGTCATCTGTGATGTACTGTTTCAGATTGGGCAGTTATGACATAAGTGAGAAGGCAAGCATGT
GTGAGTGAAGATTAGAGGGTCACATATAACTGGCTGTTTTCTGTTCTTGTTTATCCAGCGTAGGAAGAAGGAAAAGAAAATCTTTGCTCC
TCTGCCCCATTCACTATTTACCAATTGGGAATTAAAGAAATAATTAATTTGAACAGTTATGAAATTAATATTTGCTGTCTGTGTGTATAA
GTACATCCTTTGGGGTTTTTTTTTTCTCTTTTTTTTAACCAAAGTTGCTGTCTAGTGCATTCAAAGGTCACTTTTTGTTCTTCACAGATC
TTTTTAATGTTCTTTCCCATGTTGTATTGCATTTTTGGGGGAAGCAAATTGACTTTAAAGAAAAAAGTTGTGGCAAAAGATGCTAAGATG
CGAAAATTTCACCACACTGAGTCAAAAAGGTGAAAAATTATCCATTTCCTATGCGTTTTACTCCTCAGAGAATGAAAAAAACTGCATCCC
ATCACCCAAAGTTCTGTGCAATAGAAATTTCTACAGATACAGGTATAGGGGCTCAAGGAGGTATGTCGGTCAGTAGTCAAAACTATGAAA
TGATACTGGTTTCTCCACAGGAATATGGTTCCATTAGGCTGGGAGCAAAAACAATGTTTTTTAAGATTGAGAATACATACCTGACAACGA
TCCGGAAACTGCTCCTCACCACTCCCGTCATGCCTGCTGTCGGCGTTTGACCTTCCACGTGACAGTTCTTCACAATTCCTTTCATCATTT
TTTAAATATTTTTTTTACTGCCTATGGGCTGTGATGTATATAGAAGTTGTACATTAAACATACCCTCATTTTTTTCTTTTCTTTTTTTTT
TTTTTTTTTAGTACAAAGTTTTAGTTTCTTTTTCATGATGTGGTAACTACGAAGTGATGGTAGATTTAAATAATTTTTTATTTTTATTTT
ATATATTTTTTCATTAGGGCCATATCTCCAAAAAAAGAAAGAAAAAATACAAAAAACAAAAACAAAAAAAAAAGAGGGTAATGTACAAGT
TTCTGTATGTATAAAGTCATGCTCGATTTCAGGAGAGCAGCTGATCACAATTTGCTTCATGAATCAAGGTGTGGAAATGGTTATATATGG
ATTGATTTAGAAAATGGTTACCAGTACAGTCAAAAAAGAGAAAATGAAAAAAATACAACTAAAAGGAAGAAACACAACTTCAAAGATTTT

>38471_38471_7_IGF1R-ARID1B_IGF1R_chr15_99251336_ENST00000558762_ARID1B_chr6_157469758_ENST00000350026_length(amino acids)=1612AA_BP=214
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRV
AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKSNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR
PFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPY
SMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPV
SSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPK
LQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMP
DVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPP
YGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQM
MGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQ
PSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKIT
SKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAAR
KDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLG
RVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQEGKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQ
TESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPE
RKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLS
PQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGV

--------------------------------------------------------------
>38471_38471_8_IGF1R-ARID1B_IGF1R_chr15_99251336_ENST00000558762_ARID1B_chr6_157469758_ENST00000367148_length(transcript)=6912nt_BP=1178nt
GGAGGGGGAGCCGCTCATTCATTTTGACTCCGCGTTTCTGCCCCTCGCCGGCCTCGCCTGTGACCCGGACTTCGGGGCGATCTTGCGAAC
TGCGTCGCGCCCTCCCGCGGCGGAAGCTCGGGCGTCCGGCCGCCTCCCGCGCGGCCAGGGCCGGGCTTGTTTTTCCTCGCCTAGGCAGAT
TTGGGCTTTGCCCCCTTTCTTTGCAGTTTTCCCCCCTTCCTGCCTCTCCGGGTTTGAAAATGGAGGCCGACGACGCCGACAGCCCGCCCC
GGCGCGCCTCGGGTTCCCGACTCCGCCGAGCCCTGGGCCGCTGCTGCCGGCGCTGAGGGGCCGCCCCGCGCCGCCCGCCCCGTCCGCGCA
CCCGGAGGGCCCCGGCGGCGCCGCCTTCGGAGTATTGTTTCCTTCGCCCTTGTTTTTGGAGGGGGAGCGAAGACTGAGTTTGAGACTTGT
TTCCTTTCATTTCCTTTTTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGAAAGGGGAATTTCATCCCAAATAAAAGGAAT
GAAGTCTGGCTCCGGAGGAGGGTCCCCGACCTCGCTGTGGGGGCTCCTGTTTCTCTCCGCCGCGCTCTCGCTCTGGCCGACGAGTGGAGA
AATCTGCGGGCCAGGCATCGACATCCGCAACGACTATCAGCAGCTGAAGCGCCTGGAGAACTGCACGGTGATCGAGGGCTACCTCCACAT
CCTGCTCATCTCCAAGGCCGAGGACTACCGCAGCTACCGCTTCCCCAAGCTCACGGTCATTACCGAGTACTTGCTGCTGTTCCGAGTGGC
TGGCCTCGAGAGCCTCGGAGACCTCTTCCCCAACCTCACGGTCATCCGCGGCTGGAAACTCTTCTACAACTACGCCCTGGTCATCTTCGA
GATGACCAATCTCAAGGATATTGGGCTTTACAACCTGAGGAACATTACTCGGGGGGCCATCAGGATTGAGAAAAATGCTGACCTCTGTTA
CCTCTCCACTGTGGACTGGTCCCTGATCCTGGATGCGGTGTCCAATAACTACATTGTGGGGAATAAGCCCCCAAAGGAATGTGGGGACCT
GTGTCCAGGGACCATGGAGGAGAAGCCGATGTGTGAGAAGACCACCATCAACAATGAGTACAACTACCGCTGCTGGACCACAAACCGCTG
CCAGAAAAGTAACTACTCCAGACCCCCAGCGTATAGTGGGGTGCCCAGTGCAAGCTACAGCGGCCCAGGGCCCGGTATGGGTATCAGTGC
CAACAACCAGATGCATGGACAAGGGCCAAGCCAGCCATGTGGTGCTGTGCCCCTGGGACGAATGCCATCAGCTGGGATGCAGAACAGACC
ATTTCCTGGAAATATGAGCAGCATGACCCCCAGTTCTCCTGGCATGTCTCAGCAGGGAGGGCCAGGAATGGGGCCGCCAATGCCAACTGT
GAACCGTAAGGCACAGGAGGCAGCCGCAGCAGTGATGCAGGCTGCTGCGAACTCAGCACAAAGCAGGCAAGGCAGTTTCCCCGGCATGAA
CCAGAGTGGACTTATGGCTTCCAGCTCTCCCTACAGCCAGCCCATGAACAACAGCTCTAGCCTGATGAACACGCAGGCGCCGCCCTACAG
CATGGCGCCCGCCATGGTGAACAGCTCGGCAGCATCTGTGGGTCTTGCAGATATGATGTCTCCTGGTGAATCCAAACTGCCCCTGCCTCT
CAAAGCAGACGGCAAAGAAGAAGGCACTCCACAGCCCGAGAGCAAGTCAAAGGATAGCTACAGCTCTCAGGGTATTTCTCAGCCCCCAAC
CCCAGGCAACCTGCCAGTCCCTTCCCCAATGTCCCCCAGCTCTGCTAGCATCTCCTCATTTCATGGAGATGAAAGTGATAGCATTAGCAG
CCCAGGCTGGCCAAAGACTCCATCAAGCCCTAAGTCCAGCTCCTCCACCACTACTGGGGAGAAGATCACGAAGGTGTACGAGCTGGGGAA
TGAGCCAGAGAGAAAGCTCTGGGTCGACCGATACCTCACCTTCATGGAAGAGAGAGGCTCTCCTGTCTCAAGTCTGCCTGCCGTGGGCAA
GAAGCCCCTGGACCTGTTCCGACTCTACGTCTGCGTCAAAGAGATCGGGGGTTTGGCCCAGGTTAATAAAAACAAGAAGTGGCGTGAGCT
GGCAACCAACCTAAACGTTGGCACCTCAAGCAGTGCAGCGAGCTCCCTGAAAAAGCAGTATATTCAGTACCTGTTTGCCTTTGAGTGCAA
GATCGAACGTGGGGAGGAGCCCCCGCCGGAAGTCTTCAGCACCGGGGACACCAAAAAGCAGCCCAAGCTCCAGCCGCCATCTCCTGCTAA
CTCGGGATCCTTGCAAGGCCCACAGACCCCCCAGTCAACTGGCAGCAATTCCATGGCAGAGGTTCCAGGTGACCTGAAGCCACCTACCCC
AGCCTCCACCCCTCACGGCCAGATGACTCCAATGCAAGGTGGAAGAAGCAGTACAATCAGTGTGCACGACCCATTCTCAGATGTGAGTGA
TTCATCCTTCCCGAAACGGAACTCCATGACTCCAAACGCCCCCTACCAGCAGGGCATGAGCATGCCCGATGTGATGGGCAGGATGCCCTA
TGAGCCCAACAAGGACCCCTTTGGGGGAATGAGAAAAGTGCCTGGAAGCAGCGAGCCCTTTATGACGCAAGGACAGATGCCCAACAGCAG
CATGCAGGACATGTACAACCAAAGTCCCTCCGGAGCAATGTCTAACCTGGGCATGGGGCAGCGCCAGCAGTTTCCCTATGGAGCCAGTTA
CGACCGAAGGCATGAACCTTATGGGCAGCAGTATCCAGGCCAAGGCCCTCCCTCGGGACAGCCGCCGTATGGAGGGCACCAGCCCGGCCT
GTACCCACAGCAGCCGAATTACAAACGCCATATGGACGGCATGTACGGGCCCCCAGCCAAGCGCCACGAGGGCGACATGTACAACATGCA
GTACAGCAGCCAGCAGCAGGAGATGTACAACCAGTATGGAGGCTCCTACTCGGGCCCGGACCGCAGGCCCATCCAGGGCCAGTACCCGTA
TCCCTACAGCAGGGAGAGGATGCAGGGCCCGGGGCAGATCCAGACACACGGAATCCCGCCTCAGATGATGGGCGGCCCGCTGCAGTCGTC
CTCCAGTGAGGGGCCTCAGCAGAATATGTGGGCAGCACGCAATGATATGCCTTATCCCTACCAGAACAGGCAGGGCCCTGGCGGCCCTAC
ACAGGCGCCCCCTTACCCAGGCATGAACCGCACAGACGATATGATGGTACCCGATCAGAGGATAAATCATGAGAGCCAGTGGCCTTCTCA
CGTCAGCCAGCGTCAGCCTTATATGTCGTCCTCAGCCTCCATGCAGCCCATCACACGCCCACCACAGCCGTCCTACCAGACGCCACCGTC
ACTGCCAAATCACATCTCCAGGGCGCCCAGCCCAGCGTCCTTCCAGCGCTCCCTGGAGAACCGCATGTCTCCAAGCAAGTCTCCTTTTCT
GCCGTCTATGAAGATGCAGAAGGTCATGCCCACGGTCCCCACATCCCAGGTCACCGGGCCACCACCCCAACCACCCCCAATCAGAAGGGA
GATCACCTTTCCTCCTGGCTCAGTAGAAGCATCACAACCAGTCTTGAAACAAAGGCGAAAGATTACCTCCAAAGATATCGTTACTCCTGA
GGCGTGGCGTGTGATGATGTCCCTTAAATCAGGTCTTTTGGCTGAGAGTACGTGGGCTTTGGACACTATTAATATTCTTCTGTATGATGA
CAGCACTGTTGCTACTTTCAATCTCTCCCAGTTGTCTGGATTTCTCGAACTTTTAGTCGAGTACTTTAGAAAATGCCTGATTGACATTTT
TGGAATTCTTATGGAATATGAAGTGGGAGACCCCAGCCAAAAAGCACTTGATCACAACGCAGCAAGGAAGGATGACAGCCAGTCCTTGGC
AGACGATTCTGGGAAAGAGGAGGAAGATGCTGAATGTATTGATGACGACGAGGAAGACGAGGAGGATGAGGAGGAAGACAGCGAGAAGAC
AGAAAGCGATGAAAAGAGCAGCATCGCTCTGACTGCCCCGGACGCCGCTGCAGACCCAAAGGAGAAGCCCAAGCAAGCCAGTAAGTTCGA
CAAGCTGCCAATAAAGATAGTCAAAAAGAACAACCTGTTTGTTGTTGACCGATCTGACAAGTTGGGGCGTGTGCAGGAGTTCAATAGTGG
CCTTCTGCACTGGCAGCTCGGCGGGGGTGACACCACCGAGCACATTCAGACTCACTTTGAGAGCAAGATGGAAATTCCTCCTCGCAGGCG
CCCACCTCCCCCCTTAAGCTCCGCAGGTAGAAAGAAAGAGCAAGAAGGCAAAGGCGACTCTGAAGAGCAGCAAGAGAAAAGCATCATAGC
AACCATCGATGACGTCCTCTCTGCTCGGCCAGGGGCATTGCCTGAAGACGCAAACCCTGGGCCCCAGACCGAAAGCAGTAAGTTTCCCTT
TGGTATCCAGCAAGCCAAAAGTCACCGGAACATCAAGCTGCTGGAGGACGAGCCCAGGAGCCGAGACGAGACTCCTCTGTGTACCATCGC
GCACTGGCAGGACTCGCTGGCTAAGCGATGCATCTGTGTGTCCAATATTGTCCGTAGCTTGTCATTCGTGCCTGGCAATGATGCCGAAAT
GTCCAAACATCCAGGCCTGGTGCTGATCCTGGGGAAGCTGATTCTTCTTCACCACGAGCATCCAGAGAGAAAGCGAGCACCGCAGACCTA
TGAGAAAGAGGAGGATGAGGACAAGGGGGTGGCCTGCAGCAAAGATGAGTGGTGGTGGGACTGCCTCGAGGTCTTGAGGGATAACACGTT
GGTCACGTTGGCCAACATTTCCGGGCAGCTAGACTTGTCTGCTTACACGGAAAGCATCTGCTTGCCAATTTTGGATGGCTTGCTGCACTG
GATGGTGTGCCCGTCTGCAGAGGCACAAGATCCCTTTCCAACTGTGGGACCCAACTCGGTCCTGTCGCCTCAGAGACTTGTGCTGGAGAC
CCTCTGTAAACTCAGTATCCAGGACAATAATGTGGACCTGATCTTGGCCACTCCTCCATTTAGTCGTCAGGAGAAATTCTATGCTACATT
AGTTAGGTACGTTGGGGATCGCAAAAACCCAGTCTGTCGAGAAATGTCCATGGCGCTTTTATCGAACCTTGCCCAAGGGGACGCACTAGC
AGCAAGGGCCATAGCTGTGCAGAAAGGAAGCATTGGAAACTTGATAAGCTTCCTAGAGGATGGGGTCACGATGGCCCAGTACCAGCAGAG
CCAGCACAACCTCATGCACATGCAGCCCCCGCCCCTGGAACCACCTAGCGTAGACATGATGTGCAGGGCGGCCAAGGCTTTGCTAGCCAT
GGCCAGAGTGGACGAAAACCGCTCGGAATTCCTTTTGCACGAGGGCCGGTTGCTGGATATCTCGATATCAGCTGTCCTGAACTCTCTGGT
TGCATCTGTCATCTGTGATGTACTGTTTCAGATTGGGCAGTTATGACATAAGTGAGAAGGCAAGCATGTGTGAGTGAAGATTAGAGGGTC
ACATATAACTGGCTGTTTTCTGTTCTTGTTTATCCAGCGTAGGAAGAAGGAAAAGAAAATCTTTGCTCCTCTGCCCCATTCACTATTTAC
CAATTGGGAATTAAAGAAATAATTAATTTGAACAGTTATGAAATTAATATTTGCTGTCTGTGTGTATAAGTACATCCTTTGGGGTTTTTT
TTTTCTCTTTTTTTTAACCAAAGTTGCTGTCTAGTGCATTCAAAGGTCACTTTTTGTTCTTCACAGATCTTTTTAATGTTCTTTCCCATG
TTGTATTGCATTTTTGGGGGAAGCAAATTGACTTTAAAGAAAAAAGTTGTGGCAAAAGATGCTAAGATGCGAAAATTTCACCACACTGAG
TCAAAAAGGTGAAAAATTATCCATTTCCTATGCGTTTTACTCCTCAGAGAATGAAAAAAACTGCATCCCATCACCCAAAGTTCTGTGCAA
TAGAAATTTCTACAGATACAGGTATAGGGGCTCAAGGAGGTATGTCGGTCAGTAGTCAAAACTATGAAATGATACTGGTTTCTCCACAGG
AATATGGTTCCATTAGGCTGGGAGCAAAAACAATGTTTTTTAAGATTGAGAATACATACCTGACAACGATCCGGAAACTGCTCCTCACCA
CTCCCGTCATGCCTGCTGTCGGCGTTTGACCTTCCACGTGACAGTTCTTCACAATTCCTTTCATCATTTTTTAAATATTTTTTTTACTGC
CTATGGGCTGTGATGTATATAGAAGTTGTACATTAAACATACCCTCATTTTTTTCTTTTCTTTTTTTTTTTTTTTTTTAGTACAAAGTTT
TAGTTTCTTTTTCATGATGTGGTAACTACGAAGTGATGGTAGATTTAAATAATTTTTTATTTTTATTTTATATATTTTTTCATTAGGGCC
ATATCTCCAAAAAAAGAAAGAAAAAATACAAAAAACAAAAACAAAAAAAAAAGAGGGTAATGTACAAGTTTCTGTATGTATAAAGTCATG
CTCGATTTCAGGAGAGCAGCTGATCACAATTTGCTTCATGAATCAAGGTGTGGAAATGGTTATATATGGATTGATTTAGAAAATGGTTAC
CAGTACAGTCAAAAAAGAGAAAATGAAAAAAATACAACTAAAAGGAAGAAACACAACTTCAAAGATTTTTCAGTGATGAGAATCCACATT
TGTATTTCAAGATAATGTAGTTTAAAAAAAAAAAAAAGAAAAAAACTTGATGTAAATTCCTCCTTTTCCTCTGGCTTAATGAATATCATT

>38471_38471_8_IGF1R-ARID1B_IGF1R_chr15_99251336_ENST00000558762_ARID1B_chr6_157469758_ENST00000367148_length(amino acids)=1665AA_BP=214
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRV
AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKSNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR
PFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPY
SMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSIS
SPGWPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRE
LATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPT
PASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNS
SMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNM
QYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGP
TQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPF
LPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYD
DSTVATFNLSQLSGFLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEK
TESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRR
RPPPPLSSAGRKKEQEGKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLCTI
AHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNT
LVTLANISGQLDLSAYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYAT
LVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLA

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Fusion Gene PPI Analysis for IGF1R-ARID1B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for IGF1R-ARID1B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneIGF1RP08069DB00046Insulin lisproBiotechApproved
HgeneIGF1RP08069DB00047Insulin glargineBiotechApproved
HgeneIGF1RP08069DB00071Insulin porkBiotechApproved
HgeneIGF1RP08069DB01306Insulin aspartBiotechApproved
HgeneIGF1RP08069DB01307Insulin detemirBiotechApproved
HgeneIGF1RP08069DB01309Insulin glulisineBiotechApproved
HgeneIGF1RP08069DB09564Insulin degludecBiotechApproved
HgeneIGF1RP08069DB14751Mecasermin rinfabateAgonistBiotechApproved
HgeneIGF1RP08069DB00030Insulin humanBiotechApproved|Investigational
HgeneIGF1RP08069DB01277MecaserminAgonistBiotechApproved|Investigational
HgeneIGF1RP08069DB06343TeprotumumabInhibitorBiotechApproved|Investigational
HgeneIGF1RP08069DB12267BrigatinibInhibitorSmall moleculeApproved|Investigational
HgeneIGF1RP08069DB09098SomatremBiotechApproved|Investigational|Withdrawn

Top

Related Diseases for IGF1R-ARID1B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneIGF1RC1849157Resistance to Insulin-Like Growth Factor I5CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneIGF1RC0004238Atrial Fibrillation2CTD_human
HgeneIGF1RC0024115Lung diseases2CTD_human
HgeneIGF1RC0235480Paroxysmal atrial fibrillation2CTD_human
HgeneIGF1RC0235833Congenital diaphragmatic hernia2CTD_human
HgeneIGF1RC0265699Congenital hernia of foramen of Morgagni2CTD_human
HgeneIGF1RC0265700Congenital hernia of foramen of Bochdalek2CTD_human
HgeneIGF1RC2239176Liver carcinoma2CTD_human
HgeneIGF1RC2585653Persistent atrial fibrillation2CTD_human
HgeneIGF1RC3468561familial atrial fibrillation2CTD_human
HgeneIGF1RC0002395Alzheimer's Disease1CTD_human
HgeneIGF1RC0006142Malignant neoplasm of breast1CTD_human
HgeneIGF1RC0007114Malignant neoplasm of skin1CTD_human
HgeneIGF1RC0007621Neoplastic Cell Transformation1CTD_human
HgeneIGF1RC0011265Presenile dementia1CTD_human
HgeneIGF1RC0014170Endometrial Neoplasms1CTD_human
HgeneIGF1RC0015934Fetal Growth Retardation1CTD_human
HgeneIGF1RC0018273Growth Disorders1CTD_human
HgeneIGF1RC0030567Parkinson Disease1CTD_human
HgeneIGF1RC0035229Respiratory Insufficiency1CTD_human
HgeneIGF1RC0037286Skin Neoplasms1CTD_human
HgeneIGF1RC0087031Juvenile-Onset Still Disease1CTD_human
HgeneIGF1RC0206686Adrenocortical carcinoma1CTD_human
HgeneIGF1RC0235063Respiratory Depression1CTD_human
HgeneIGF1RC0276496Familial Alzheimer Disease (FAD)1CTD_human
HgeneIGF1RC0424605Developmental delay (disorder)1GENOMICS_ENGLAND
HgeneIGF1RC0476089Endometrial Carcinoma1CTD_human
HgeneIGF1RC0494463Alzheimer Disease, Late Onset1CTD_human
HgeneIGF1RC0546126Acute Confusional Senile Dementia1CTD_human
HgeneIGF1RC0557874Global developmental delay1GENOMICS_ENGLAND
HgeneIGF1RC0678222Breast Carcinoma1CTD_human
HgeneIGF1RC0750900Alzheimer's Disease, Focal Onset1CTD_human
HgeneIGF1RC0750901Alzheimer Disease, Early Onset1CTD_human
HgeneIGF1RC0752347Lewy Body Disease1CTD_human
HgeneIGF1RC1145670Respiratory Failure1CTD_human
HgeneIGF1RC1257931Mammary Neoplasms, Human1CTD_human
HgeneIGF1RC1458155Mammary Neoplasms1CTD_human
HgeneIGF1RC3495559Juvenile arthritis1CTD_human
HgeneIGF1RC3714758Juvenile psoriatic arthritis1CTD_human
HgeneIGF1RC4552091Polyarthritis, Juvenile, Rheumatoid Factor Negative1CTD_human
HgeneIGF1RC4704862Polyarthritis, Juvenile, Rheumatoid Factor Positive1CTD_human
HgeneIGF1RC4704874Mammary Carcinoma, Human1CTD_human
HgeneIGF1RC4721453Peripheral Nervous System Diseases1CTD_human
TgeneC0265338Coffin-Siris syndrome7CLINGEN;CTD_human;GENOMICS_ENGLAND
TgeneC1535926Neurodevelopmental Disorders2CTD_human
TgeneC3281201MENTAL RETARDATION, AUTOSOMAL DOMINANT 122GENOMICS_ENGLAND
TgeneC0014544Epilepsy1CTD_human
TgeneC0019569Hirschsprung Disease1GENOMICS_ENGLAND
TgeneC0027819Neuroblastoma1CTD_human
TgeneC0086237Epilepsy, Cryptogenic1CTD_human
TgeneC0236018Aura1CTD_human
TgeneC0751111Awakening Epilepsy1CTD_human
TgeneC2239176Liver carcinoma1CGI;CTD_human
TgeneC3150215CHROMOSOME 6q24-q25 DELETION SYNDROME1ORPHANET