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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:ATP9B-LUC7L (FusionGDB2 ID:HG374868TG55692)

Fusion Gene Summary for ATP9B-LUC7L

check button Fusion gene summary
Fusion gene informationFusion gene name: ATP9B-LUC7L
Fusion gene ID: hg374868tg55692
HgeneTgene
Gene symbol

ATP9B

LUC7L

Gene ID

374868

55692

Gene nameATPase phospholipid transporting 9B (putative)LUC7 like
SynonymsATPASEP|ATPIIB|HUSSY-20|NEO1L|hMMR1LUC7B1|Luc7|SR+89|hLuc7B1
Cytomap('ATP9B')('LUC7L')

18q23

16p13.3

Type of geneprotein-codingprotein-coding
Descriptionprobable phospholipid-transporting ATPase IIBATPase type IV, phospholipid transporting (P-type)ATPase, class II, type 9Bmacrophage MHC receptor 1putative RNA-binding protein Luc7-like 1putative SR protein LUC7B1sarcoplasmic reticulum protein LUC7B1
Modification date2020031320200320
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000307671, ENST00000426216, 
ENST00000458297, ENST00000543761, 
ENST00000586722, ENST00000591464, 
Fusion gene scores* DoF score15 X 16 X 5=120012 X 8 X 8=768
# samples 1517
** MAII scorelog2(15/1200*10)=-3
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(17/768*10)=-2.17557156458345
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ATP9B [Title/Abstract] AND LUC7L [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointATP9B(76953263)-LUC7L(258187), # samples:4
Anticipated loss of major functional domain due to fusion event.ATP9B-LUC7L seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ATP9B-LUC7L seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ATP9B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across LUC7L (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-3B-A9HU-01AATP9Bchr18

76953263

+LUC7Lchr16

258187

-
ChimerDB4SARCTCGA-DX-A1L0-01AATP9Bchr18

76953263

-LUC7Lchr16

258187

-
ChimerDB4SARCTCGA-DX-A1L0-01AATP9Bchr18

76953263

+LUC7Lchr16

258187

-


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Fusion Gene ORF analysis for ATP9B-LUC7L

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000307671ENST00000494366ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
5CDS-intronENST00000426216ENST00000494366ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
In-frameENST00000307671ENST00000293872ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
In-frameENST00000307671ENST00000337351ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
In-frameENST00000307671ENST00000397780ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
In-frameENST00000307671ENST00000397783ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
In-frameENST00000426216ENST00000293872ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
In-frameENST00000426216ENST00000337351ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
In-frameENST00000426216ENST00000397780ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
In-frameENST00000426216ENST00000397783ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-3CDSENST00000458297ENST00000293872ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-3CDSENST00000458297ENST00000337351ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-3CDSENST00000458297ENST00000397780ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-3CDSENST00000458297ENST00000397783ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-3CDSENST00000543761ENST00000293872ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-3CDSENST00000543761ENST00000337351ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-3CDSENST00000543761ENST00000397780ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-3CDSENST00000543761ENST00000397783ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-3CDSENST00000586722ENST00000293872ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-3CDSENST00000586722ENST00000337351ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-3CDSENST00000586722ENST00000397780ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-3CDSENST00000586722ENST00000397783ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-3CDSENST00000591464ENST00000293872ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-3CDSENST00000591464ENST00000337351ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-3CDSENST00000591464ENST00000397780ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-3CDSENST00000591464ENST00000397783ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-intronENST00000458297ENST00000494366ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-intronENST00000543761ENST00000494366ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-intronENST00000586722ENST00000494366ATP9Bchr18

76953263

+LUC7Lchr16

258187

-
intron-intronENST00000591464ENST00000494366ATP9Bchr18

76953263

+LUC7Lchr16

258187

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000426216ATP9Bchr1876953263+ENST00000293872LUC7Lchr16258187-2061971171831604
ENST00000426216ATP9Bchr1876953263+ENST00000337351LUC7Lchr16258187-2689971171693558
ENST00000426216ATP9Bchr1876953263+ENST00000397783LUC7Lchr16258187-2096971171693558
ENST00000426216ATP9Bchr1876953263+ENST00000397780LUC7Lchr16258187-1762971171693558
ENST00000307671ATP9Bchr1876953263+ENST00000293872LUC7Lchr16258187-2058968141828604
ENST00000307671ATP9Bchr1876953263+ENST00000337351LUC7Lchr16258187-2686968141690558
ENST00000307671ATP9Bchr1876953263+ENST00000397783LUC7Lchr16258187-2093968141690558
ENST00000307671ATP9Bchr1876953263+ENST00000397780LUC7Lchr16258187-1759968141690558

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000426216ENST00000293872ATP9Bchr1876953263+LUC7Lchr16258187-0.0020098190.99799013
ENST00000426216ENST00000337351ATP9Bchr1876953263+LUC7Lchr16258187-0.0010349910.998965
ENST00000426216ENST00000397783ATP9Bchr1876953263+LUC7Lchr16258187-0.0020245070.9979755
ENST00000426216ENST00000397780ATP9Bchr1876953263+LUC7Lchr16258187-0.0022841210.99771595
ENST00000307671ENST00000293872ATP9Bchr1876953263+LUC7Lchr16258187-0.002032470.99796754
ENST00000307671ENST00000337351ATP9Bchr1876953263+LUC7Lchr16258187-0.0010554850.9989446
ENST00000307671ENST00000397783ATP9Bchr1876953263+LUC7Lchr16258187-0.0020487990.9979512
ENST00000307671ENST00000397780ATP9Bchr1876953263+LUC7Lchr16258187-0.0023257820.99767417

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Fusion Genomic Features for ATP9B-LUC7L


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ATP9B-LUC7L


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:76953263/chr16:258187)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+929169_1733181137.0Topological domainExtracellular
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+9291_1463181137.0Topological domainCytoplasmic
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+930169_1733181148.0Topological domainExtracellular
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+9301_1463181148.0Topological domainCytoplasmic
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+929147_1683181137.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+929174_1963181137.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+930147_1683181148.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+930174_1963181148.0TransmembraneHelical
TgeneLUC7Lchr18:76953263chr16:258187ENST00000293872210218_25985372.0Coiled coilOntology_term=ECO:0000255
TgeneLUC7Lchr18:76953263chr16:258187ENST0000029387221087_17785372.0Coiled coilOntology_term=ECO:0000255
TgeneLUC7Lchr18:76953263chr16:258187ENST0000033735129218_25985326.0Coiled coilOntology_term=ECO:0000255
TgeneLUC7Lchr18:76953263chr16:258187ENST000003373512987_17785326.0Coiled coilOntology_term=ECO:0000255
TgeneLUC7Lchr18:76953263chr16:258187ENST00000397783210218_25985424.0Coiled coilOntology_term=ECO:0000255
TgeneLUC7Lchr18:76953263chr16:258187ENST0000039778321087_17785424.0Coiled coilOntology_term=ECO:0000255
TgeneLUC7Lchr18:76953263chr16:258187ENST00000293872210243_36285372.0Compositional biasNote=Arg/Ser-rich
TgeneLUC7Lchr18:76953263chr16:258187ENST0000033735129243_36285326.0Compositional biasNote=Arg/Ser-rich
TgeneLUC7Lchr18:76953263chr16:258187ENST00000397783210243_36285424.0Compositional biasNote=Arg/Ser-rich

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+9291032_10383181137.0Topological domainExtracellular
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+9291062_10673181137.0Topological domainCytoplasmic
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+9291089_11053181137.0Topological domainExtracellular
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+9291131_11473181137.0Topological domainCytoplasmic
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+929197_3803181137.0Topological domainCytoplasmic
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+929402_4093181137.0Topological domainExtracellular
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+929432_9303181137.0Topological domainCytoplasmic
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+929952_9633181137.0Topological domainExtracellular
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+929983_10123181137.0Topological domainCytoplasmic
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+9301032_10383181148.0Topological domainExtracellular
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+9301062_10673181148.0Topological domainCytoplasmic
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+9301089_11053181148.0Topological domainExtracellular
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+9301131_11473181148.0Topological domainCytoplasmic
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+930197_3803181148.0Topological domainCytoplasmic
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+930402_4093181148.0Topological domainExtracellular
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+930432_9303181148.0Topological domainCytoplasmic
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+930952_9633181148.0Topological domainExtracellular
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+930983_10123181148.0Topological domainCytoplasmic
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+9291013_10313181137.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+9291039_10613181137.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+9291068_10883181137.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+9291106_11303181137.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+929381_4013181137.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+929410_4313181137.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+929931_9513181137.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000307671+929964_9823181137.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+9301013_10313181148.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+9301039_10613181148.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+9301068_10883181148.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+9301106_11303181148.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+930381_4013181148.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+930410_4313181148.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+930931_9513181148.0TransmembraneHelical
HgeneATP9Bchr18:76953263chr16:258187ENST00000426216+930964_9823181148.0TransmembraneHelical


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Fusion Gene Sequence for ATP9B-LUC7L


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>8301_8301_1_ATP9B-LUC7L_ATP9B_chr18_76953263_ENST00000307671_LUC7L_chr16_258187_ENST00000293872_length(transcript)=2058nt_BP=968nt
GGGGCGGTCGGAACATGGCGGACCAGATCCCGCTTTACCCGGTGCGTAGCGCAGCGGCGGCCGCAGCCAACCGCAAACGCGCGGCCTACT
ACAGCGCCGCGGGGCCCAGGCCGGGAGCCGACCGGCACAGCAGGTACCAGCTGGAGGATGAGTCTGCGCATTTGGATGAAATGCCACTAA
TGATGTCTGAAGAAGGCTTTGAGAATGAGGAAAGTGATTACCACACCTTACCACGAGCCAGGATAATGCAAAGGAAAAGAGGACTGGAGT
GGTTTGTCTGTGATGGCTGGAAGTTCCTCTGTACCAGTTGCTGTGGTTGGCTGATAAATATTTGTCGAAGAAAGAAAGAGCTGAAAGCTC
GCACAGTATGGCTTGGATGTCCTGAAAAGTGTGAAGAAAAACATCCCAGGAATTCTATAAAAAATCAAAAATACAATGTGTTTACCTTTA
TACCTGGGGTTTTGTATGAACAATTCAAGTTTTTCTTGAATCTCTATTTTCTAGTAATATCCTGCTCACAGTTTGTACCAGCATTGAAAA
TAGGCTATCTCTACACCTACTGGGCTCCTCTGGGATTTGTCTTGGCTGTTACTATGACACGGGAAGCAATTGATGAATTTCGGCGTTTTC
AGCGTGACAAGGAAGTGAATTCACAACTATATAGCAAGCTTACAGTAAGAGGTAAAGTGCAAGTTAAGAGTTCAGACATACAAGTTGGAG
ACCTCATCATAGTGGAAAAGAATCAAAGAATTCCATCGGACATGGTGTTTCTTAGGACTTCAGAAAAAGCAGGTTCGTGTTTTATTCGAA
CTGATCAACTAGATGGTGAAACTGACTGGAAGCTGAAGGTGGCAGTGAGCTGCACGCAACAGCTGCCGGCTCTGGGGGACCTTTTTTCTA
TCAGTGCTTATGTTTATGCTCAGAAACCACAAATGGACATTCACAGTTTCGAAGGCACATTTACCAGGGCAATGGATCACTTGGAGTCCT
TTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGCAGAAACACAGGAGGAAATCAGTGCGGAAGTTTCTGCAAAGG
CAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAAAGCCGAACAGCTAGGGGCTGAAGGTAATGTGGATGAATCCC
AGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGCTGAGGAAGAATACAGAAATTCCATGCCTGCATCCAGTTTTC
AGCAGCAAAAGCTGCGTGTCTGCGAGGTCTGTTCAGCCTACCTTGGTCTCCATGACAATGACCGTCGCCTGGCAGACCACTTCGGTGGCA
AGTTACACTTGGGGTTCATTCAGATCCGAGAGAAGCTTGATCAGTTGAGGAAAACTGTCGCTGAAAAGCAGGAGAAGAGAAATCAGGATC
GCTTGAGGAGGAGAGAGGAGAGGGAACGGGAGGAGCGTCTGAGCAGGAGGTCGGGATCAAGAACCAGAGATCGCAGGAGGTCACGCTCCC
GGGATCGGCGTCGGAGGCGGTCAAGATCTACCTCCCGAGAGCGACGGAAATTGTCCCGGTCCCGGTCCCGAGATAGACATCGGCGCCACC
GCAGCCGTTCCCGGAGCCACAGCCGGGGACATCGTCGGGCTTCCCGGGACCGAAGTGCGAAATACAAGTTCTCCAGAGAGCGGGCATCCA
GAGAGGAGTCCTGGGAGAGCGGGCGGAGCGAGCGAGGGCCCCCGGACTGGAGGCTTGAGAGCTCCAACGGGAAGATGGCTTCACGGAGGT
CAGAAGAGAAGGAGGCCGGCGAGATCTGAACCCGTCTCCCGGGTGCTGTAAATAGTCTGATAAACGTTCACACAGTCTAAAATTACCCTT
TATATTTGCTGAATACAACTCATCTTTTGTAGTTTAAAATTTCTATTGTTTTGGAGCTAGCTGTGAGTTTCTAGAAGTGTACAGAGTTGC

>8301_8301_1_ATP9B-LUC7L_ATP9B_chr18_76953263_ENST00000307671_LUC7L_chr16_258187_ENST00000293872_length(amino acids)=604AA_BP=318
MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEEGFENEESDYHTLPRARIMQRKRGLEWFVCD
GWKFLCTSCCGWLINICRRKKELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLY
TYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLD
GETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTRAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVH
ELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG
FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSR

--------------------------------------------------------------
>8301_8301_2_ATP9B-LUC7L_ATP9B_chr18_76953263_ENST00000307671_LUC7L_chr16_258187_ENST00000337351_length(transcript)=2686nt_BP=968nt
GGGGCGGTCGGAACATGGCGGACCAGATCCCGCTTTACCCGGTGCGTAGCGCAGCGGCGGCCGCAGCCAACCGCAAACGCGCGGCCTACT
ACAGCGCCGCGGGGCCCAGGCCGGGAGCCGACCGGCACAGCAGGTACCAGCTGGAGGATGAGTCTGCGCATTTGGATGAAATGCCACTAA
TGATGTCTGAAGAAGGCTTTGAGAATGAGGAAAGTGATTACCACACCTTACCACGAGCCAGGATAATGCAAAGGAAAAGAGGACTGGAGT
GGTTTGTCTGTGATGGCTGGAAGTTCCTCTGTACCAGTTGCTGTGGTTGGCTGATAAATATTTGTCGAAGAAAGAAAGAGCTGAAAGCTC
GCACAGTATGGCTTGGATGTCCTGAAAAGTGTGAAGAAAAACATCCCAGGAATTCTATAAAAAATCAAAAATACAATGTGTTTACCTTTA
TACCTGGGGTTTTGTATGAACAATTCAAGTTTTTCTTGAATCTCTATTTTCTAGTAATATCCTGCTCACAGTTTGTACCAGCATTGAAAA
TAGGCTATCTCTACACCTACTGGGCTCCTCTGGGATTTGTCTTGGCTGTTACTATGACACGGGAAGCAATTGATGAATTTCGGCGTTTTC
AGCGTGACAAGGAAGTGAATTCACAACTATATAGCAAGCTTACAGTAAGAGGTAAAGTGCAAGTTAAGAGTTCAGACATACAAGTTGGAG
ACCTCATCATAGTGGAAAAGAATCAAAGAATTCCATCGGACATGGTGTTTCTTAGGACTTCAGAAAAAGCAGGTTCGTGTTTTATTCGAA
CTGATCAACTAGATGGTGAAACTGACTGGAAGCTGAAGGTGGCAGTGAGCTGCACGCAACAGCTGCCGGCTCTGGGGGACCTTTTTTCTA
TCAGTGCTTATGTTTATGCTCAGAAACCACAAATGGACATTCACAGTTTCGAAGGCACATTTACCAGGGCAATGGATCACTTGGAGTCCT
TTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGCAGAAACACAGGAGGAAATCAGTGCGGAAGTTTCTGCAAAGG
CAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAAAGCCGAACAGCTAGGGGCTGAAGGTAATGTGGATGAATCCC
AGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGCTGAGGAAGAATACAGAAATTCCATGCCTGCATCCAGTTTTC
AGCAGCAAAAGCTGCGTGTCTGCGAGGTCTGTTCAGCCTACCTTGGTCTCCATGACAATGACCGTCGCCTGGCAGACCACTTCGGTGGCA
AGTTACACTTGGGGTTCATTCAGATCCGAGAGAAGCTTGATCAGTTGAGGAAAACTGTCGCTGAAAAGCAGGAGAAGAGAAATCAGGATC
GCTTGAGGAGGAGAGAGGAGAGGGAACGGGAGGAGCGTCTGAGCAGGAGGTCGGGATCAAGAACCAGAGATCGCAGGAGGTCACGCTCCC
GGGATCGGCGTCGGAGGCGGTCAAGATCTACCTCCCGAGAGCGACGGAAATTGTCCCGGTCCCGGTCCCGAGATAGACATCGGCGCCACC
GCAGCCGTTCCCGGAGCCACAGCCGGGGACATCGTCGGGCTTCCCGGGACCGAAGTGCGAAATACAAGTAACTACTCTGACTCCTTCGGT
AGCTGCAACCAGGAGTGAGCCCTTCTCTGTGTTCCCAGGGTCTGCTGAGGGCCGTGTCTGGTGGGGATGGGGCTGGGCTCACCCTCAGGA
GTAGGGCTGGGGAGTCGTGAACGGGACTCAGGTGTGGGAAGAGGCGAGAGGGCTGTGGAGGAGCTCGCACGGCGCCAGGTGATGGGCTGC
ACAGGCACTGTCCCCTGCCTGCGTCCTGGGGCCTGTGCACTGTTGCGTCCATGCTCAGAGTGGCTGAGACTTGTGTCCTGACCAGGCCCT
GCTTACCTCTGTTTTGGTTTTTGTTTTTGATATTTTTTTTTCCATTGTGTTTTTACGTAGTGTCATGTTCTGTGCATATAGTGTTGTATT
CTCCTTTGCACTGTTTATGTTACAGTGAAGGCTCTCCTTATTAAAAATCTTCGCAAAGGTCACTTTTTAATGGCTATCTAACACTCCATA
TGTGGTGGGCAAGTCTGGTTGGCCTCCGGGGGGTTTCCAGGTATAGGGGATGTAGGGCCTTGCCTGGCCTGGTCTGCGGGTCCATCGTCA
GTGCCTGAGCGGCCAGCAGAAGGGGGGCAGCAGCCTCCACTGAGCCTCTGGTTCCCATTTCCCAGGTTCTCCAGAGAGCGGGCATCCAGA
GAGGAGTCCTGGGAGAGCGGGCGGAGCGAGCGAGGGCCCCCGGACTGGAGGCTTGAGAGCTCCAACGGGAAGATGGCTTCACGGAGGTCA
GAAGAGAAGGAGGCCGGCGAGATCTGAACCCGTCTCCCGGGTGCTGTAAATAGTCTGATAAACGTTCACACAGTCTAAAATTACCCTTTA
TATTTGCTGAATACAACTCATCTTTTGTAGTTTAAAATTTCTATTGTTTTGGAGCTAGCTGTGAGTTTCTAGAAGTGTACAGAGTTGCTC

>8301_8301_2_ATP9B-LUC7L_ATP9B_chr18_76953263_ENST00000307671_LUC7L_chr16_258187_ENST00000337351_length(amino acids)=558AA_BP=318
MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEEGFENEESDYHTLPRARIMQRKRGLEWFVCD
GWKFLCTSCCGWLINICRRKKELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLY
TYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLD
GETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTRAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVH
ELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG
FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSR

--------------------------------------------------------------
>8301_8301_3_ATP9B-LUC7L_ATP9B_chr18_76953263_ENST00000307671_LUC7L_chr16_258187_ENST00000397780_length(transcript)=1759nt_BP=968nt
GGGGCGGTCGGAACATGGCGGACCAGATCCCGCTTTACCCGGTGCGTAGCGCAGCGGCGGCCGCAGCCAACCGCAAACGCGCGGCCTACT
ACAGCGCCGCGGGGCCCAGGCCGGGAGCCGACCGGCACAGCAGGTACCAGCTGGAGGATGAGTCTGCGCATTTGGATGAAATGCCACTAA
TGATGTCTGAAGAAGGCTTTGAGAATGAGGAAAGTGATTACCACACCTTACCACGAGCCAGGATAATGCAAAGGAAAAGAGGACTGGAGT
GGTTTGTCTGTGATGGCTGGAAGTTCCTCTGTACCAGTTGCTGTGGTTGGCTGATAAATATTTGTCGAAGAAAGAAAGAGCTGAAAGCTC
GCACAGTATGGCTTGGATGTCCTGAAAAGTGTGAAGAAAAACATCCCAGGAATTCTATAAAAAATCAAAAATACAATGTGTTTACCTTTA
TACCTGGGGTTTTGTATGAACAATTCAAGTTTTTCTTGAATCTCTATTTTCTAGTAATATCCTGCTCACAGTTTGTACCAGCATTGAAAA
TAGGCTATCTCTACACCTACTGGGCTCCTCTGGGATTTGTCTTGGCTGTTACTATGACACGGGAAGCAATTGATGAATTTCGGCGTTTTC
AGCGTGACAAGGAAGTGAATTCACAACTATATAGCAAGCTTACAGTAAGAGGTAAAGTGCAAGTTAAGAGTTCAGACATACAAGTTGGAG
ACCTCATCATAGTGGAAAAGAATCAAAGAATTCCATCGGACATGGTGTTTCTTAGGACTTCAGAAAAAGCAGGTTCGTGTTTTATTCGAA
CTGATCAACTAGATGGTGAAACTGACTGGAAGCTGAAGGTGGCAGTGAGCTGCACGCAACAGCTGCCGGCTCTGGGGGACCTTTTTTCTA
TCAGTGCTTATGTTTATGCTCAGAAACCACAAATGGACATTCACAGTTTCGAAGGCACATTTACCAGGGCAATGGATCACTTGGAGTCCT
TTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGCAGAAACACAGGAGGAAATCAGTGCGGAAGTTTCTGCAAAGG
CAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAAAGCCGAACAGCTAGGGGCTGAAGGTAATGTGGATGAATCCC
AGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGCTGAGGAAGAATACAGAAATTCCATGCCTGCATCCAGTTTTC
AGCAGCAAAAGCTGCGTGTCTGCGAGGTCTGTTCAGCCTACCTTGGTCTCCATGACAATGACCGTCGCCTGGCAGACCACTTCGGTGGCA
AGTTACACTTGGGGTTCATTCAGATCCGAGAGAAGCTTGATCAGTTGAGGAAAACTGTCGCTGAAAAGCAGGAGAAGAGAAATCAGGATC
GCTTGAGGAGGAGAGAGGAGAGGGAACGGGAGGAGCGTCTGAGCAGGAGGTCGGGATCAAGAACCAGAGATCGCAGGAGGTCACGCTCCC
GGGATCGGCGTCGGAGGCGGTCAAGATCTACCTCCCGAGAGCGACGGAAATTGTCCCGGTCCCGGTCCCGAGATAGACATCGGCGCCACC
GCAGCCGTTCCCGGAGCCACAGCCGGGGACATCGTCGGGCTTCCCGGGACCGAAGTGCGAAATACAAGTAACTACTCTGACTCCTTCGGT

>8301_8301_3_ATP9B-LUC7L_ATP9B_chr18_76953263_ENST00000307671_LUC7L_chr16_258187_ENST00000397780_length(amino acids)=558AA_BP=318
MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEEGFENEESDYHTLPRARIMQRKRGLEWFVCD
GWKFLCTSCCGWLINICRRKKELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLY
TYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLD
GETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTRAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVH
ELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG
FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSR

--------------------------------------------------------------
>8301_8301_4_ATP9B-LUC7L_ATP9B_chr18_76953263_ENST00000307671_LUC7L_chr16_258187_ENST00000397783_length(transcript)=2093nt_BP=968nt
GGGGCGGTCGGAACATGGCGGACCAGATCCCGCTTTACCCGGTGCGTAGCGCAGCGGCGGCCGCAGCCAACCGCAAACGCGCGGCCTACT
ACAGCGCCGCGGGGCCCAGGCCGGGAGCCGACCGGCACAGCAGGTACCAGCTGGAGGATGAGTCTGCGCATTTGGATGAAATGCCACTAA
TGATGTCTGAAGAAGGCTTTGAGAATGAGGAAAGTGATTACCACACCTTACCACGAGCCAGGATAATGCAAAGGAAAAGAGGACTGGAGT
GGTTTGTCTGTGATGGCTGGAAGTTCCTCTGTACCAGTTGCTGTGGTTGGCTGATAAATATTTGTCGAAGAAAGAAAGAGCTGAAAGCTC
GCACAGTATGGCTTGGATGTCCTGAAAAGTGTGAAGAAAAACATCCCAGGAATTCTATAAAAAATCAAAAATACAATGTGTTTACCTTTA
TACCTGGGGTTTTGTATGAACAATTCAAGTTTTTCTTGAATCTCTATTTTCTAGTAATATCCTGCTCACAGTTTGTACCAGCATTGAAAA
TAGGCTATCTCTACACCTACTGGGCTCCTCTGGGATTTGTCTTGGCTGTTACTATGACACGGGAAGCAATTGATGAATTTCGGCGTTTTC
AGCGTGACAAGGAAGTGAATTCACAACTATATAGCAAGCTTACAGTAAGAGGTAAAGTGCAAGTTAAGAGTTCAGACATACAAGTTGGAG
ACCTCATCATAGTGGAAAAGAATCAAAGAATTCCATCGGACATGGTGTTTCTTAGGACTTCAGAAAAAGCAGGTTCGTGTTTTATTCGAA
CTGATCAACTAGATGGTGAAACTGACTGGAAGCTGAAGGTGGCAGTGAGCTGCACGCAACAGCTGCCGGCTCTGGGGGACCTTTTTTCTA
TCAGTGCTTATGTTTATGCTCAGAAACCACAAATGGACATTCACAGTTTCGAAGGCACATTTACCAGGGCAATGGATCACTTGGAGTCCT
TTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGCAGAAACACAGGAGGAAATCAGTGCGGAAGTTTCTGCAAAGG
CAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAAAGCCGAACAGCTAGGGGCTGAAGGTAATGTGGATGAATCCC
AGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGCTGAGGAAGAATACAGAAATTCCATGCCTGCATCCAGTTTTC
AGCAGCAAAAGCTGCGTGTCTGCGAGGTCTGTTCAGCCTACCTTGGTCTCCATGACAATGACCGTCGCCTGGCAGACCACTTCGGTGGCA
AGTTACACTTGGGGTTCATTCAGATCCGAGAGAAGCTTGATCAGTTGAGGAAAACTGTCGCTGAAAAGCAGGAGAAGAGAAATCAGGATC
GCTTGAGGAGGAGAGAGGAGAGGGAACGGGAGGAGCGTCTGAGCAGGAGGTCGGGATCAAGAACCAGAGATCGCAGGAGGTCACGCTCCC
GGGATCGGCGTCGGAGGCGGTCAAGATCTACCTCCCGAGAGCGACGGAAATTGTCCCGGTCCCGGTCCCGAGATAGACATCGGCGCCACC
GCAGCCGTTCCCGGAGCCACAGCCGGGGACATCGTCGGGCTTCCCGGGACCGAAGTGCGAAATACAAGTAACTACTCTGACTCCTTCGGT
AGCTGCAACCAGGAGTTCTCCAGAGAGCGGGCATCCAGAGAGGAGTCCTGGGAGAGCGGGCGGAGCGAGCGAGGGCCCCCGGACTGGAGG
CTTGAGAGCTCCAACGGGAAGATGGCTTCACGGAGGTCAGAAGAGAAGGAGGCCGGCGAGATCTGAACCCGTCTCCCGGGTGCTGTAAAT
AGTCTGATAAACGTTCACACAGTCTAAAATTACCCTTTATATTTGCTGAATACAACTCATCTTTTGTAGTTTAAAATTTCTATTGTTTTG
GAGCTAGCTGTGAGTTTCTAGAAGTGTACAGAGTTGCTCCTGTGTTCCCGGGTCATGTTGAGTAGGAATAAATAAATCTGATGCTGCCTC

>8301_8301_4_ATP9B-LUC7L_ATP9B_chr18_76953263_ENST00000307671_LUC7L_chr16_258187_ENST00000397783_length(amino acids)=558AA_BP=318
MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEEGFENEESDYHTLPRARIMQRKRGLEWFVCD
GWKFLCTSCCGWLINICRRKKELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLY
TYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLD
GETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTRAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVH
ELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG
FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSR

--------------------------------------------------------------
>8301_8301_5_ATP9B-LUC7L_ATP9B_chr18_76953263_ENST00000426216_LUC7L_chr16_258187_ENST00000293872_length(transcript)=2061nt_BP=971nt
AAAGGGGCGGTCGGAACATGGCGGACCAGATCCCGCTTTACCCGGTGCGTAGCGCAGCGGCGGCCGCAGCCAACCGCAAACGCGCGGCCT
ACTACAGCGCCGCGGGGCCCAGGCCGGGAGCCGACCGGCACAGCAGGTACCAGCTGGAGGATGAGTCTGCGCATTTGGATGAAATGCCAC
TAATGATGTCTGAAGAAGGCTTTGAGAATGAGGAAAGTGATTACCACACCTTACCACGAGCCAGGATAATGCAAAGGAAAAGAGGACTGG
AGTGGTTTGTCTGTGATGGCTGGAAGTTCCTCTGTACCAGTTGCTGTGGTTGGCTGATAAATATTTGTCGAAGAAAGAAAGAGCTGAAAG
CTCGCACAGTATGGCTTGGATGTCCTGAAAAGTGTGAAGAAAAACATCCCAGGAATTCTATAAAAAATCAAAAATACAATGTGTTTACCT
TTATACCTGGGGTTTTGTATGAACAATTCAAGTTTTTCTTGAATCTCTATTTTCTAGTAATATCCTGCTCACAGTTTGTACCAGCATTGA
AAATAGGCTATCTCTACACCTACTGGGCTCCTCTGGGATTTGTCTTGGCTGTTACTATGACACGGGAAGCAATTGATGAATTTCGGCGTT
TTCAGCGTGACAAGGAAGTGAATTCACAACTATATAGCAAGCTTACAGTAAGAGGTAAAGTGCAAGTTAAGAGTTCAGACATACAAGTTG
GAGACCTCATCATAGTGGAAAAGAATCAAAGAATTCCATCGGACATGGTGTTTCTTAGGACTTCAGAAAAAGCAGGTTCGTGTTTTATTC
GAACTGATCAACTAGATGGTGAAACTGACTGGAAGCTGAAGGTGGCAGTGAGCTGCACGCAACAGCTGCCGGCTCTGGGGGACCTTTTTT
CTATCAGTGCTTATGTTTATGCTCAGAAACCACAAATGGACATTCACAGTTTCGAAGGCACATTTACCAGGGCAATGGATCACTTGGAGT
CCTTTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGCAGAAACACAGGAGGAAATCAGTGCGGAAGTTTCTGCAA
AGGCAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAAAGCCGAACAGCTAGGGGCTGAAGGTAATGTGGATGAAT
CCCAGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGCTGAGGAAGAATACAGAAATTCCATGCCTGCATCCAGTT
TTCAGCAGCAAAAGCTGCGTGTCTGCGAGGTCTGTTCAGCCTACCTTGGTCTCCATGACAATGACCGTCGCCTGGCAGACCACTTCGGTG
GCAAGTTACACTTGGGGTTCATTCAGATCCGAGAGAAGCTTGATCAGTTGAGGAAAACTGTCGCTGAAAAGCAGGAGAAGAGAAATCAGG
ATCGCTTGAGGAGGAGAGAGGAGAGGGAACGGGAGGAGCGTCTGAGCAGGAGGTCGGGATCAAGAACCAGAGATCGCAGGAGGTCACGCT
CCCGGGATCGGCGTCGGAGGCGGTCAAGATCTACCTCCCGAGAGCGACGGAAATTGTCCCGGTCCCGGTCCCGAGATAGACATCGGCGCC
ACCGCAGCCGTTCCCGGAGCCACAGCCGGGGACATCGTCGGGCTTCCCGGGACCGAAGTGCGAAATACAAGTTCTCCAGAGAGCGGGCAT
CCAGAGAGGAGTCCTGGGAGAGCGGGCGGAGCGAGCGAGGGCCCCCGGACTGGAGGCTTGAGAGCTCCAACGGGAAGATGGCTTCACGGA
GGTCAGAAGAGAAGGAGGCCGGCGAGATCTGAACCCGTCTCCCGGGTGCTGTAAATAGTCTGATAAACGTTCACACAGTCTAAAATTACC
CTTTATATTTGCTGAATACAACTCATCTTTTGTAGTTTAAAATTTCTATTGTTTTGGAGCTAGCTGTGAGTTTCTAGAAGTGTACAGAGT

>8301_8301_5_ATP9B-LUC7L_ATP9B_chr18_76953263_ENST00000426216_LUC7L_chr16_258187_ENST00000293872_length(amino acids)=604AA_BP=318
MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEEGFENEESDYHTLPRARIMQRKRGLEWFVCD
GWKFLCTSCCGWLINICRRKKELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLY
TYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLD
GETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTRAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVH
ELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG
FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSR

--------------------------------------------------------------
>8301_8301_6_ATP9B-LUC7L_ATP9B_chr18_76953263_ENST00000426216_LUC7L_chr16_258187_ENST00000337351_length(transcript)=2689nt_BP=971nt
AAAGGGGCGGTCGGAACATGGCGGACCAGATCCCGCTTTACCCGGTGCGTAGCGCAGCGGCGGCCGCAGCCAACCGCAAACGCGCGGCCT
ACTACAGCGCCGCGGGGCCCAGGCCGGGAGCCGACCGGCACAGCAGGTACCAGCTGGAGGATGAGTCTGCGCATTTGGATGAAATGCCAC
TAATGATGTCTGAAGAAGGCTTTGAGAATGAGGAAAGTGATTACCACACCTTACCACGAGCCAGGATAATGCAAAGGAAAAGAGGACTGG
AGTGGTTTGTCTGTGATGGCTGGAAGTTCCTCTGTACCAGTTGCTGTGGTTGGCTGATAAATATTTGTCGAAGAAAGAAAGAGCTGAAAG
CTCGCACAGTATGGCTTGGATGTCCTGAAAAGTGTGAAGAAAAACATCCCAGGAATTCTATAAAAAATCAAAAATACAATGTGTTTACCT
TTATACCTGGGGTTTTGTATGAACAATTCAAGTTTTTCTTGAATCTCTATTTTCTAGTAATATCCTGCTCACAGTTTGTACCAGCATTGA
AAATAGGCTATCTCTACACCTACTGGGCTCCTCTGGGATTTGTCTTGGCTGTTACTATGACACGGGAAGCAATTGATGAATTTCGGCGTT
TTCAGCGTGACAAGGAAGTGAATTCACAACTATATAGCAAGCTTACAGTAAGAGGTAAAGTGCAAGTTAAGAGTTCAGACATACAAGTTG
GAGACCTCATCATAGTGGAAAAGAATCAAAGAATTCCATCGGACATGGTGTTTCTTAGGACTTCAGAAAAAGCAGGTTCGTGTTTTATTC
GAACTGATCAACTAGATGGTGAAACTGACTGGAAGCTGAAGGTGGCAGTGAGCTGCACGCAACAGCTGCCGGCTCTGGGGGACCTTTTTT
CTATCAGTGCTTATGTTTATGCTCAGAAACCACAAATGGACATTCACAGTTTCGAAGGCACATTTACCAGGGCAATGGATCACTTGGAGT
CCTTTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGCAGAAACACAGGAGGAAATCAGTGCGGAAGTTTCTGCAA
AGGCAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAAAGCCGAACAGCTAGGGGCTGAAGGTAATGTGGATGAAT
CCCAGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGCTGAGGAAGAATACAGAAATTCCATGCCTGCATCCAGTT
TTCAGCAGCAAAAGCTGCGTGTCTGCGAGGTCTGTTCAGCCTACCTTGGTCTCCATGACAATGACCGTCGCCTGGCAGACCACTTCGGTG
GCAAGTTACACTTGGGGTTCATTCAGATCCGAGAGAAGCTTGATCAGTTGAGGAAAACTGTCGCTGAAAAGCAGGAGAAGAGAAATCAGG
ATCGCTTGAGGAGGAGAGAGGAGAGGGAACGGGAGGAGCGTCTGAGCAGGAGGTCGGGATCAAGAACCAGAGATCGCAGGAGGTCACGCT
CCCGGGATCGGCGTCGGAGGCGGTCAAGATCTACCTCCCGAGAGCGACGGAAATTGTCCCGGTCCCGGTCCCGAGATAGACATCGGCGCC
ACCGCAGCCGTTCCCGGAGCCACAGCCGGGGACATCGTCGGGCTTCCCGGGACCGAAGTGCGAAATACAAGTAACTACTCTGACTCCTTC
GGTAGCTGCAACCAGGAGTGAGCCCTTCTCTGTGTTCCCAGGGTCTGCTGAGGGCCGTGTCTGGTGGGGATGGGGCTGGGCTCACCCTCA
GGAGTAGGGCTGGGGAGTCGTGAACGGGACTCAGGTGTGGGAAGAGGCGAGAGGGCTGTGGAGGAGCTCGCACGGCGCCAGGTGATGGGC
TGCACAGGCACTGTCCCCTGCCTGCGTCCTGGGGCCTGTGCACTGTTGCGTCCATGCTCAGAGTGGCTGAGACTTGTGTCCTGACCAGGC
CCTGCTTACCTCTGTTTTGGTTTTTGTTTTTGATATTTTTTTTTCCATTGTGTTTTTACGTAGTGTCATGTTCTGTGCATATAGTGTTGT
ATTCTCCTTTGCACTGTTTATGTTACAGTGAAGGCTCTCCTTATTAAAAATCTTCGCAAAGGTCACTTTTTAATGGCTATCTAACACTCC
ATATGTGGTGGGCAAGTCTGGTTGGCCTCCGGGGGGTTTCCAGGTATAGGGGATGTAGGGCCTTGCCTGGCCTGGTCTGCGGGTCCATCG
TCAGTGCCTGAGCGGCCAGCAGAAGGGGGGCAGCAGCCTCCACTGAGCCTCTGGTTCCCATTTCCCAGGTTCTCCAGAGAGCGGGCATCC
AGAGAGGAGTCCTGGGAGAGCGGGCGGAGCGAGCGAGGGCCCCCGGACTGGAGGCTTGAGAGCTCCAACGGGAAGATGGCTTCACGGAGG
TCAGAAGAGAAGGAGGCCGGCGAGATCTGAACCCGTCTCCCGGGTGCTGTAAATAGTCTGATAAACGTTCACACAGTCTAAAATTACCCT
TTATATTTGCTGAATACAACTCATCTTTTGTAGTTTAAAATTTCTATTGTTTTGGAGCTAGCTGTGAGTTTCTAGAAGTGTACAGAGTTG

>8301_8301_6_ATP9B-LUC7L_ATP9B_chr18_76953263_ENST00000426216_LUC7L_chr16_258187_ENST00000337351_length(amino acids)=558AA_BP=318
MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEEGFENEESDYHTLPRARIMQRKRGLEWFVCD
GWKFLCTSCCGWLINICRRKKELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLY
TYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLD
GETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTRAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVH
ELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG
FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSR

--------------------------------------------------------------
>8301_8301_7_ATP9B-LUC7L_ATP9B_chr18_76953263_ENST00000426216_LUC7L_chr16_258187_ENST00000397780_length(transcript)=1762nt_BP=971nt
AAAGGGGCGGTCGGAACATGGCGGACCAGATCCCGCTTTACCCGGTGCGTAGCGCAGCGGCGGCCGCAGCCAACCGCAAACGCGCGGCCT
ACTACAGCGCCGCGGGGCCCAGGCCGGGAGCCGACCGGCACAGCAGGTACCAGCTGGAGGATGAGTCTGCGCATTTGGATGAAATGCCAC
TAATGATGTCTGAAGAAGGCTTTGAGAATGAGGAAAGTGATTACCACACCTTACCACGAGCCAGGATAATGCAAAGGAAAAGAGGACTGG
AGTGGTTTGTCTGTGATGGCTGGAAGTTCCTCTGTACCAGTTGCTGTGGTTGGCTGATAAATATTTGTCGAAGAAAGAAAGAGCTGAAAG
CTCGCACAGTATGGCTTGGATGTCCTGAAAAGTGTGAAGAAAAACATCCCAGGAATTCTATAAAAAATCAAAAATACAATGTGTTTACCT
TTATACCTGGGGTTTTGTATGAACAATTCAAGTTTTTCTTGAATCTCTATTTTCTAGTAATATCCTGCTCACAGTTTGTACCAGCATTGA
AAATAGGCTATCTCTACACCTACTGGGCTCCTCTGGGATTTGTCTTGGCTGTTACTATGACACGGGAAGCAATTGATGAATTTCGGCGTT
TTCAGCGTGACAAGGAAGTGAATTCACAACTATATAGCAAGCTTACAGTAAGAGGTAAAGTGCAAGTTAAGAGTTCAGACATACAAGTTG
GAGACCTCATCATAGTGGAAAAGAATCAAAGAATTCCATCGGACATGGTGTTTCTTAGGACTTCAGAAAAAGCAGGTTCGTGTTTTATTC
GAACTGATCAACTAGATGGTGAAACTGACTGGAAGCTGAAGGTGGCAGTGAGCTGCACGCAACAGCTGCCGGCTCTGGGGGACCTTTTTT
CTATCAGTGCTTATGTTTATGCTCAGAAACCACAAATGGACATTCACAGTTTCGAAGGCACATTTACCAGGGCAATGGATCACTTGGAGT
CCTTTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGCAGAAACACAGGAGGAAATCAGTGCGGAAGTTTCTGCAA
AGGCAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAAAGCCGAACAGCTAGGGGCTGAAGGTAATGTGGATGAAT
CCCAGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGCTGAGGAAGAATACAGAAATTCCATGCCTGCATCCAGTT
TTCAGCAGCAAAAGCTGCGTGTCTGCGAGGTCTGTTCAGCCTACCTTGGTCTCCATGACAATGACCGTCGCCTGGCAGACCACTTCGGTG
GCAAGTTACACTTGGGGTTCATTCAGATCCGAGAGAAGCTTGATCAGTTGAGGAAAACTGTCGCTGAAAAGCAGGAGAAGAGAAATCAGG
ATCGCTTGAGGAGGAGAGAGGAGAGGGAACGGGAGGAGCGTCTGAGCAGGAGGTCGGGATCAAGAACCAGAGATCGCAGGAGGTCACGCT
CCCGGGATCGGCGTCGGAGGCGGTCAAGATCTACCTCCCGAGAGCGACGGAAATTGTCCCGGTCCCGGTCCCGAGATAGACATCGGCGCC
ACCGCAGCCGTTCCCGGAGCCACAGCCGGGGACATCGTCGGGCTTCCCGGGACCGAAGTGCGAAATACAAGTAACTACTCTGACTCCTTC

>8301_8301_7_ATP9B-LUC7L_ATP9B_chr18_76953263_ENST00000426216_LUC7L_chr16_258187_ENST00000397780_length(amino acids)=558AA_BP=318
MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEEGFENEESDYHTLPRARIMQRKRGLEWFVCD
GWKFLCTSCCGWLINICRRKKELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLY
TYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLD
GETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTRAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVH
ELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG
FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSR

--------------------------------------------------------------
>8301_8301_8_ATP9B-LUC7L_ATP9B_chr18_76953263_ENST00000426216_LUC7L_chr16_258187_ENST00000397783_length(transcript)=2096nt_BP=971nt
AAAGGGGCGGTCGGAACATGGCGGACCAGATCCCGCTTTACCCGGTGCGTAGCGCAGCGGCGGCCGCAGCCAACCGCAAACGCGCGGCCT
ACTACAGCGCCGCGGGGCCCAGGCCGGGAGCCGACCGGCACAGCAGGTACCAGCTGGAGGATGAGTCTGCGCATTTGGATGAAATGCCAC
TAATGATGTCTGAAGAAGGCTTTGAGAATGAGGAAAGTGATTACCACACCTTACCACGAGCCAGGATAATGCAAAGGAAAAGAGGACTGG
AGTGGTTTGTCTGTGATGGCTGGAAGTTCCTCTGTACCAGTTGCTGTGGTTGGCTGATAAATATTTGTCGAAGAAAGAAAGAGCTGAAAG
CTCGCACAGTATGGCTTGGATGTCCTGAAAAGTGTGAAGAAAAACATCCCAGGAATTCTATAAAAAATCAAAAATACAATGTGTTTACCT
TTATACCTGGGGTTTTGTATGAACAATTCAAGTTTTTCTTGAATCTCTATTTTCTAGTAATATCCTGCTCACAGTTTGTACCAGCATTGA
AAATAGGCTATCTCTACACCTACTGGGCTCCTCTGGGATTTGTCTTGGCTGTTACTATGACACGGGAAGCAATTGATGAATTTCGGCGTT
TTCAGCGTGACAAGGAAGTGAATTCACAACTATATAGCAAGCTTACAGTAAGAGGTAAAGTGCAAGTTAAGAGTTCAGACATACAAGTTG
GAGACCTCATCATAGTGGAAAAGAATCAAAGAATTCCATCGGACATGGTGTTTCTTAGGACTTCAGAAAAAGCAGGTTCGTGTTTTATTC
GAACTGATCAACTAGATGGTGAAACTGACTGGAAGCTGAAGGTGGCAGTGAGCTGCACGCAACAGCTGCCGGCTCTGGGGGACCTTTTTT
CTATCAGTGCTTATGTTTATGCTCAGAAACCACAAATGGACATTCACAGTTTCGAAGGCACATTTACCAGGGCAATGGATCACTTGGAGT
CCTTTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGCAGAAACACAGGAGGAAATCAGTGCGGAAGTTTCTGCAA
AGGCAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAAAGCCGAACAGCTAGGGGCTGAAGGTAATGTGGATGAAT
CCCAGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGCTGAGGAAGAATACAGAAATTCCATGCCTGCATCCAGTT
TTCAGCAGCAAAAGCTGCGTGTCTGCGAGGTCTGTTCAGCCTACCTTGGTCTCCATGACAATGACCGTCGCCTGGCAGACCACTTCGGTG
GCAAGTTACACTTGGGGTTCATTCAGATCCGAGAGAAGCTTGATCAGTTGAGGAAAACTGTCGCTGAAAAGCAGGAGAAGAGAAATCAGG
ATCGCTTGAGGAGGAGAGAGGAGAGGGAACGGGAGGAGCGTCTGAGCAGGAGGTCGGGATCAAGAACCAGAGATCGCAGGAGGTCACGCT
CCCGGGATCGGCGTCGGAGGCGGTCAAGATCTACCTCCCGAGAGCGACGGAAATTGTCCCGGTCCCGGTCCCGAGATAGACATCGGCGCC
ACCGCAGCCGTTCCCGGAGCCACAGCCGGGGACATCGTCGGGCTTCCCGGGACCGAAGTGCGAAATACAAGTAACTACTCTGACTCCTTC
GGTAGCTGCAACCAGGAGTTCTCCAGAGAGCGGGCATCCAGAGAGGAGTCCTGGGAGAGCGGGCGGAGCGAGCGAGGGCCCCCGGACTGG
AGGCTTGAGAGCTCCAACGGGAAGATGGCTTCACGGAGGTCAGAAGAGAAGGAGGCCGGCGAGATCTGAACCCGTCTCCCGGGTGCTGTA
AATAGTCTGATAAACGTTCACACAGTCTAAAATTACCCTTTATATTTGCTGAATACAACTCATCTTTTGTAGTTTAAAATTTCTATTGTT
TTGGAGCTAGCTGTGAGTTTCTAGAAGTGTACAGAGTTGCTCCTGTGTTCCCGGGTCATGTTGAGTAGGAATAAATAAATCTGATGCTGC

>8301_8301_8_ATP9B-LUC7L_ATP9B_chr18_76953263_ENST00000426216_LUC7L_chr16_258187_ENST00000397783_length(amino acids)=558AA_BP=318
MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEEGFENEESDYHTLPRARIMQRKRGLEWFVCD
GWKFLCTSCCGWLINICRRKKELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLY
TYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLD
GETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTRAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVH
ELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG
FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ATP9B-LUC7L


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ATP9B-LUC7L


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ATP9B-LUC7L


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneATP9BC0009171Cocaine Abuse1CTD_human
HgeneATP9BC0236736Cocaine-Related Disorders1CTD_human
HgeneATP9BC0600427Cocaine Dependence1CTD_human