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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:KCNMA1-FARP1 (FusionGDB2 ID:HG3778TG10160)

Fusion Gene Summary for KCNMA1-FARP1

check button Fusion gene summary
Fusion gene informationFusion gene name: KCNMA1-FARP1
Fusion gene ID: hg3778tg10160
HgeneTgene
Gene symbol

KCNMA1

FARP1

Gene ID

3778

10160

Gene namepotassium calcium-activated channel subfamily M alpha 1FERM, ARH/RhoGEF and pleckstrin domain protein 1
SynonymsBKTM|CADEDS|IEG16|KCa1.1|LIWAS|MaxiK|PNKD3|SAKCA|SLO|SLO-ALPHA|SLO1|bA205K10.1|hSlo|mSLO1CDEP|FARP1-IT1|PLEKHC2|PPP1R75
Cytomap('KCNMA1')('FARP1')

10q22.3

13q32.2

Type of geneprotein-codingprotein-coding
Descriptioncalcium-activated potassium channel subunit alpha-1uncharacterized proteinBK channel alpha subunitBKCA alpha subunitbig potassium channel alpha subunitcalcium-activated potassium channel, subfamily M subunit alpha-1k(VCA)alphamaxi-K channel HSLOpoFERM, ARHGEF and pleckstrin domain-containing protein 1FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)FERM, RhoGEF and pleckstrin domain-containing protein 1PH domain-containing family C member 2chondrocyte-derived ezrin-li
Modification date2020031520200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000286627, ENST00000286628, 
ENST00000354353, ENST00000372440, 
ENST00000372443, ENST00000404771, 
ENST00000404857, ENST00000406533, 
ENST00000480683, ENST00000481070, 
ENST00000484507, 
Fusion gene scores* DoF score20 X 17 X 10=340019 X 19 X 8=2888
# samples 2522
** MAII scorelog2(25/3400*10)=-3.76553474636298
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(22/2888*10)=-3.71449531336251
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KCNMA1 [Title/Abstract] AND FARP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKCNMA1(79397023)-FARP1(98865474), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneKCNMA1

GO:0001666

response to hypoxia

15528406

HgeneKCNMA1

GO:0006813

potassium ion transport

7573516|7877450|11245614|12388065|17706472|18458941

HgeneKCNMA1

GO:0006970

response to osmotic stress

10840032|12388065

HgeneKCNMA1

GO:0030007

cellular potassium ion homeostasis

11245614

HgeneKCNMA1

GO:0034465

response to carbon monoxide

15528406

HgeneKCNMA1

GO:0042391

regulation of membrane potential

7877450|7993625

HgeneKCNMA1

GO:0045794

negative regulation of cell volume

12388065

HgeneKCNMA1

GO:0051592

response to calcium ion

12388065|18458941

HgeneKCNMA1

GO:0060073

micturition

11641143

HgeneKCNMA1

GO:0060083

smooth muscle contraction involved in micturition

11641143

TgeneFARP1

GO:0010923

negative regulation of phosphatase activity

19389623



check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-HC-7209-01AKCNMA1chr10

79397023

-FARP1chr13

98865474

+
ChimerDB4PRADTCGA-HC-7209KCNMA1chr10

79397022

-FARP1chr13

98865473

+
ChimerDB4PRADTCGA-HC-7209KCNMA1chr10

79397023

-FARP1chr13

98865474

+


Top

Fusion Gene ORF analysis for KCNMA1-FARP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000286627ENST00000319562KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000286627ENST00000319562KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000286627ENST00000376581KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000286627ENST00000376581KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000286627ENST00000376586KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000286627ENST00000376586KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000286627ENST00000595437KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000286627ENST00000595437KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000286628ENST00000319562KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000286628ENST00000319562KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000286628ENST00000376581KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000286628ENST00000376581KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000286628ENST00000376586KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000286628ENST00000376586KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000286628ENST00000595437KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000286628ENST00000595437KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000354353ENST00000319562KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000354353ENST00000319562KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000354353ENST00000376581KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000354353ENST00000376581KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000354353ENST00000376586KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000354353ENST00000376586KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000354353ENST00000595437KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000354353ENST00000595437KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000372440ENST00000319562KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000372440ENST00000319562KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000372440ENST00000376581KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000372440ENST00000376581KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000372440ENST00000376586KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000372440ENST00000376586KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000372440ENST00000595437KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000372440ENST00000595437KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000372443ENST00000319562KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000372443ENST00000319562KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000372443ENST00000376581KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000372443ENST00000376581KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000372443ENST00000376586KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000372443ENST00000376586KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000372443ENST00000595437KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000372443ENST00000595437KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000404771ENST00000319562KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000404771ENST00000319562KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000404771ENST00000376581KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000404771ENST00000376581KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000404771ENST00000376586KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000404771ENST00000376586KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000404771ENST00000595437KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000404771ENST00000595437KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000404857ENST00000319562KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000404857ENST00000319562KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000404857ENST00000376581KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000404857ENST00000376581KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000404857ENST00000376586KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000404857ENST00000376586KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000404857ENST00000595437KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000404857ENST00000595437KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000406533ENST00000319562KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000406533ENST00000319562KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000406533ENST00000376581KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000406533ENST00000376581KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000406533ENST00000376586KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000406533ENST00000376586KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000406533ENST00000595437KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000406533ENST00000595437KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000480683ENST00000319562KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000480683ENST00000319562KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000480683ENST00000376581KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000480683ENST00000376581KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000480683ENST00000376586KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000480683ENST00000376586KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000480683ENST00000595437KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000480683ENST00000595437KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000481070ENST00000319562KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000481070ENST00000319562KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000481070ENST00000376581KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000481070ENST00000376581KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000481070ENST00000376586KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000481070ENST00000376586KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-5UTRENST00000481070ENST00000595437KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-5UTRENST00000481070ENST00000595437KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-intronENST00000286627ENST00000593990KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-intronENST00000286627ENST00000593990KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-intronENST00000286628ENST00000593990KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-intronENST00000286628ENST00000593990KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-intronENST00000354353ENST00000593990KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-intronENST00000354353ENST00000593990KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-intronENST00000372440ENST00000593990KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-intronENST00000372440ENST00000593990KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-intronENST00000372443ENST00000593990KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-intronENST00000372443ENST00000593990KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-intronENST00000404771ENST00000593990KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-intronENST00000404771ENST00000593990KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-intronENST00000404857ENST00000593990KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-intronENST00000404857ENST00000593990KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-intronENST00000406533ENST00000593990KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-intronENST00000406533ENST00000593990KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-intronENST00000480683ENST00000593990KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-intronENST00000480683ENST00000593990KCNMA1chr10

79397022

-FARP1chr13

98865473

+
5CDS-intronENST00000481070ENST00000593990KCNMA1chr10

79397023

-FARP1chr13

98865474

+
5CDS-intronENST00000481070ENST00000593990KCNMA1chr10

79397022

-FARP1chr13

98865473

+
intron-5UTRENST00000484507ENST00000319562KCNMA1chr10

79397023

-FARP1chr13

98865474

+
intron-5UTRENST00000484507ENST00000319562KCNMA1chr10

79397022

-FARP1chr13

98865473

+
intron-5UTRENST00000484507ENST00000376581KCNMA1chr10

79397023

-FARP1chr13

98865474

+
intron-5UTRENST00000484507ENST00000376581KCNMA1chr10

79397022

-FARP1chr13

98865473

+
intron-5UTRENST00000484507ENST00000376586KCNMA1chr10

79397023

-FARP1chr13

98865474

+
intron-5UTRENST00000484507ENST00000376586KCNMA1chr10

79397022

-FARP1chr13

98865473

+
intron-5UTRENST00000484507ENST00000595437KCNMA1chr10

79397023

-FARP1chr13

98865474

+
intron-5UTRENST00000484507ENST00000595437KCNMA1chr10

79397022

-FARP1chr13

98865473

+
intron-intronENST00000484507ENST00000593990KCNMA1chr10

79397023

-FARP1chr13

98865474

+
intron-intronENST00000484507ENST00000593990KCNMA1chr10

79397022

-FARP1chr13

98865473

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for KCNMA1-FARP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
KCNMA1chr1079397022-FARP1chr1398865473+5.91E-091
KCNMA1chr1079397022-FARP1chr1398865473+5.91E-091
KCNMA1chr1079397022-FARP1chr1398865473+5.91E-091
KCNMA1chr1079397022-FARP1chr1398865473+5.91E-091


check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for KCNMA1-FARP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:79397023/:98865474)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for KCNMA1-FARP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for KCNMA1-FARP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for KCNMA1-FARP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for KCNMA1-FARP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneKCNMA1C1836173Generalized Epilepsy and Paroxysmal Dyskinesia3CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneKCNMA1C0004352Autistic Disorder1CTD_human
HgeneKCNMA1C0005944Metabolic Bone Disorder1CTD_human
HgeneKCNMA1C0007134Renal Cell Carcinoma1CTD_human
HgeneKCNMA1C0018273Growth Disorders1CTD_human
HgeneKCNMA1C0019284Diaphragmatic Hernia1CTD_human
HgeneKCNMA1C0020542Pulmonary Hypertension1CTD_human
HgeneKCNMA1C0028754Obesity1CTD_human
HgeneKCNMA1C0028756Obesity, Morbid1CTD_human
HgeneKCNMA1C0029453Osteopenia1CTD_human
HgeneKCNMA1C0038220Status Epilepticus1CTD_human
HgeneKCNMA1C0043094Weight Gain1CTD_human
HgeneKCNMA1C0270823Petit mal status1CTD_human
HgeneKCNMA1C0279702Conventional (Clear Cell) Renal Cell Carcinoma1CTD_human
HgeneKCNMA1C0311335Grand Mal Status Epilepticus1CTD_human
HgeneKCNMA1C0393734Complex Partial Status Epilepticus1CTD_human
HgeneKCNMA1C0410916Neonatal Death1CTD_human
HgeneKCNMA1C0701826Perinatal death1CTD_human
HgeneKCNMA1C0751522Status Epilepticus, Subclinical1CTD_human
HgeneKCNMA1C0751523Non-Convulsive Status Epilepticus1CTD_human
HgeneKCNMA1C0751524Simple Partial Status Epilepticus1CTD_human
HgeneKCNMA1C1266042Chromophobe Renal Cell Carcinoma1CTD_human
HgeneKCNMA1C1266043Sarcomatoid Renal Cell Carcinoma1CTD_human
HgeneKCNMA1C1266044Collecting Duct Carcinoma of the Kidney1CTD_human
HgeneKCNMA1C1306837Papillary Renal Cell Carcinoma1CTD_human
HgeneKCNMA1C4539985CEREBELLAR ATROPHY, DEVELOPMENTAL DELAY, AND SEIZURES1GENOMICS_ENGLAND
TgeneC0013146Drug abuse1CTD_human
TgeneC0013170Drug habituation1CTD_human
TgeneC0013222Drug Use Disorders1CTD_human
TgeneC0029231Organic Mental Disorders, Substance-Induced1CTD_human
TgeneC0038580Substance Dependence1CTD_human
TgeneC0038586Substance Use Disorders1CTD_human
TgeneC0236969Substance-Related Disorders1CTD_human
TgeneC0740858Substance abuse problem1CTD_human
TgeneC1510472Drug Dependence1CTD_human
TgeneC4316881Prescription Drug Abuse1CTD_human