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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NHLRC3-BPTF (FusionGDB2 ID:HG387921TG2186)

Fusion Gene Summary for NHLRC3-BPTF

check button Fusion gene summary
Fusion gene informationFusion gene name: NHLRC3-BPTF
Fusion gene ID: hg387921tg2186
HgeneTgene
Gene symbol

NHLRC3

BPTF

Gene ID

387921

2186

Gene nameNHL repeat containing 3bromodomain PHD finger transcription factor
Synonyms-FAC1|FALZ|NEDDFL|NURF301
Cytomap('NHLRC3')('BPTF')

13q13.3

17q24.2

Type of geneprotein-codingprotein-coding
DescriptionNHL repeat-containing protein 3nucleosome-remodeling factor subunit BPTFbromodomain and PHD domain transcription factorbromodomain and PHD finger-containing transcription factorfetal Alz-50 clone 1 proteinfetal Alz-50 reactive clone 1fetal Alzheimer antigennucleosome remodeling f
Modification date2020031320200313
UniProtAcc

Q5JS37

.
Ensembl transtripts involved in fusion geneENST00000379599, ENST00000379600, 
ENST00000470258, 
Fusion gene scores* DoF score8 X 3 X 4=9623 X 23 X 6=3174
# samples 726
** MAII scorelog2(7/96*10)=-0.45567948377619
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(26/3174*10)=-3.60971859980673
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NHLRC3 [Title/Abstract] AND BPTF [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNHLRC3(39613848)-BPTF(65941525), # samples:1
Anticipated loss of major functional domain due to fusion event.NHLRC3-BPTF seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
NHLRC3-BPTF seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
NHLRC3-BPTF seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
NHLRC3-BPTF seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneBPTF

GO:0000122

negative regulation of transcription by RNA polymerase II

10727212

TgeneBPTF

GO:0006338

chromatin remodeling

14609955


check buttonFusion gene breakpoints across NHLRC3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across BPTF (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CD-A4MH-01ANHLRC3chr13

39613848

+BPTFchr17

65941525

+


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Fusion Gene ORF analysis for NHLRC3-BPTF

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000379599ENST00000577770NHLRC3chr13

39613848

+BPTFchr17

65941525

+
5CDS-intronENST00000379600ENST00000577770NHLRC3chr13

39613848

+BPTFchr17

65941525

+
5UTR-3CDSENST00000470258ENST00000306378NHLRC3chr13

39613848

+BPTFchr17

65941525

+
5UTR-3CDSENST00000470258ENST00000321892NHLRC3chr13

39613848

+BPTFchr17

65941525

+
5UTR-3CDSENST00000470258ENST00000335221NHLRC3chr13

39613848

+BPTFchr17

65941525

+
5UTR-3CDSENST00000470258ENST00000424123NHLRC3chr13

39613848

+BPTFchr17

65941525

+
5UTR-intronENST00000470258ENST00000577770NHLRC3chr13

39613848

+BPTFchr17

65941525

+
In-frameENST00000379599ENST00000306378NHLRC3chr13

39613848

+BPTFchr17

65941525

+
In-frameENST00000379599ENST00000321892NHLRC3chr13

39613848

+BPTFchr17

65941525

+
In-frameENST00000379599ENST00000335221NHLRC3chr13

39613848

+BPTFchr17

65941525

+
In-frameENST00000379599ENST00000424123NHLRC3chr13

39613848

+BPTFchr17

65941525

+
In-frameENST00000379600ENST00000306378NHLRC3chr13

39613848

+BPTFchr17

65941525

+
In-frameENST00000379600ENST00000321892NHLRC3chr13

39613848

+BPTFchr17

65941525

+
In-frameENST00000379600ENST00000335221NHLRC3chr13

39613848

+BPTFchr17

65941525

+
In-frameENST00000379600ENST00000424123NHLRC3chr13

39613848

+BPTFchr17

65941525

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000379600NHLRC3chr1339613848+ENST00000335221BPTFchr1765941525+44317071452340731
ENST00000379600NHLRC3chr1339613848+ENST00000321892BPTFchr1765941525+48607071452769874
ENST00000379600NHLRC3chr1339613848+ENST00000306378BPTFchr1765941525+36357071452769874
ENST00000379600NHLRC3chr1339613848+ENST00000424123BPTFchr1765941525+23417071452340732
ENST00000379599NHLRC3chr1339613848+ENST00000335221BPTFchr1765941525+4358634722267731
ENST00000379599NHLRC3chr1339613848+ENST00000321892BPTFchr1765941525+4787634722696874
ENST00000379599NHLRC3chr1339613848+ENST00000306378BPTFchr1765941525+3562634722696874
ENST00000379599NHLRC3chr1339613848+ENST00000424123BPTFchr1765941525+2268634722267731

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000379600ENST00000335221NHLRC3chr1339613848+BPTFchr1765941525+0.000521790.9994783
ENST00000379600ENST00000321892NHLRC3chr1339613848+BPTFchr1765941525+0.0004071360.99959284
ENST00000379600ENST00000306378NHLRC3chr1339613848+BPTFchr1765941525+0.0010421020.9989579
ENST00000379600ENST00000424123NHLRC3chr1339613848+BPTFchr1765941525+0.0030257940.99697423
ENST00000379599ENST00000335221NHLRC3chr1339613848+BPTFchr1765941525+0.0005285160.9994715
ENST00000379599ENST00000321892NHLRC3chr1339613848+BPTFchr1765941525+0.0004222530.9995777
ENST00000379599ENST00000306378NHLRC3chr1339613848+BPTFchr1765941525+0.0011077910.99889225
ENST00000379599ENST00000424123NHLRC3chr1339613848+BPTFchr1765941525+0.0032239580.99677604

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Fusion Genomic Features for NHLRC3-BPTF


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NHLRC3chr1339613848+BPTFchr1765941524+0.0241924670.9758076
NHLRC3chr1339613848+BPTFchr1765941524+0.0241924670.9758076

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for NHLRC3-BPTF


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:39613848/chr17:65941525)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NHLRC3

Q5JS37

.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNHLRC3chr13:39613848chr17:65941525ENST00000379599+3647_93128281.0RepeatNote=NHL 1
HgeneNHLRC3chr13:39613848chr17:65941525ENST00000379600+3747_93128348.0RepeatNote=NHL 1
TgeneBPTFchr13:39613848chr17:65941525ENST0000030637819282706_273222332921.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr13:39613848chr17:65941525ENST0000032189221302706_273223593047.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr13:39613848chr17:65941525ENST0000033522121302706_273223592904.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr13:39613848chr17:65941525ENST0000030637819282338_236122332921.0Compositional biasNote=Thr-rich
TgeneBPTFchr13:39613848chr17:65941525ENST0000030637819282795_281722332921.0Compositional biasNote=Pro-rich
TgeneBPTFchr13:39613848chr17:65941525ENST0000030637819282848_285322332921.0Compositional biasNote=Poly-Lys
TgeneBPTFchr13:39613848chr17:65941525ENST0000032189221302795_281723593047.0Compositional biasNote=Pro-rich
TgeneBPTFchr13:39613848chr17:65941525ENST0000032189221302848_285323593047.0Compositional biasNote=Poly-Lys
TgeneBPTFchr13:39613848chr17:65941525ENST0000033522121302795_281723592904.0Compositional biasNote=Pro-rich
TgeneBPTFchr13:39613848chr17:65941525ENST0000033522121302848_285323592904.0Compositional biasNote=Poly-Lys
TgeneBPTFchr13:39613848chr17:65941525ENST0000030637819282944_301422332921.0DomainBromo
TgeneBPTFchr13:39613848chr17:65941525ENST0000032189221302944_301423593047.0DomainBromo
TgeneBPTFchr13:39613848chr17:65941525ENST0000033522121302944_301423592904.0DomainBromo
TgeneBPTFchr13:39613848chr17:65941525ENST0000030637819282867_291822332921.0Zinc fingerPHD-type 2
TgeneBPTFchr13:39613848chr17:65941525ENST0000032189221302867_291823593047.0Zinc fingerPHD-type 2
TgeneBPTFchr13:39613848chr17:65941525ENST0000033522121302867_291823592904.0Zinc fingerPHD-type 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNHLRC3chr13:39613848chr17:65941525ENST00000379599+36150_196128281.0RepeatNote=NHL 2
HgeneNHLRC3chr13:39613848chr17:65941525ENST00000379599+36200_243128281.0RepeatNote=NHL 3
HgeneNHLRC3chr13:39613848chr17:65941525ENST00000379599+36294_338128281.0RepeatNote=NHL 4
HgeneNHLRC3chr13:39613848chr17:65941525ENST00000379600+37150_196128348.0RepeatNote=NHL 2
HgeneNHLRC3chr13:39613848chr17:65941525ENST00000379600+37200_243128348.0RepeatNote=NHL 3
HgeneNHLRC3chr13:39613848chr17:65941525ENST00000379600+37294_338128348.0RepeatNote=NHL 4
TgeneBPTFchr13:39613848chr17:65941525ENST0000030637819282022_205022332921.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr13:39613848chr17:65941525ENST000003063781928574_60422332921.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr13:39613848chr17:65941525ENST000003063781928978_100722332921.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr13:39613848chr17:65941525ENST0000032189221302022_205023593047.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr13:39613848chr17:65941525ENST000003218922130574_60423593047.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr13:39613848chr17:65941525ENST000003218922130978_100723593047.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr13:39613848chr17:65941525ENST0000033522121302022_205023592904.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr13:39613848chr17:65941525ENST000003352212130574_60423592904.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr13:39613848chr17:65941525ENST000003352212130978_100723592904.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr13:39613848chr17:65941525ENST000003063781928143_18022332921.0Compositional biasNote=Glu-rich
TgeneBPTFchr13:39613848chr17:65941525ENST000003063781928149_18522332921.0Compositional biasNote=Asp-rich
TgeneBPTFchr13:39613848chr17:65941525ENST0000030637819281709_180322332921.0Compositional biasNote=Thr-rich
TgeneBPTFchr13:39613848chr17:65941525ENST000003218922130143_18023593047.0Compositional biasNote=Glu-rich
TgeneBPTFchr13:39613848chr17:65941525ENST000003218922130149_18523593047.0Compositional biasNote=Asp-rich
TgeneBPTFchr13:39613848chr17:65941525ENST0000032189221301709_180323593047.0Compositional biasNote=Thr-rich
TgeneBPTFchr13:39613848chr17:65941525ENST0000032189221302338_236123593047.0Compositional biasNote=Thr-rich
TgeneBPTFchr13:39613848chr17:65941525ENST000003352212130143_18023592904.0Compositional biasNote=Glu-rich
TgeneBPTFchr13:39613848chr17:65941525ENST000003352212130149_18523592904.0Compositional biasNote=Asp-rich
TgeneBPTFchr13:39613848chr17:65941525ENST0000033522121301709_180323592904.0Compositional biasNote=Thr-rich
TgeneBPTFchr13:39613848chr17:65941525ENST0000033522121302338_236123592904.0Compositional biasNote=Thr-rich
TgeneBPTFchr13:39613848chr17:65941525ENST000003063781928240_30022332921.0DomainDDT
TgeneBPTFchr13:39613848chr17:65941525ENST000003218922130240_30023593047.0DomainDDT
TgeneBPTFchr13:39613848chr17:65941525ENST000003352212130240_30023592904.0DomainDDT
TgeneBPTFchr13:39613848chr17:65941525ENST000003063781928390_43722332921.0Zinc fingerPHD-type 1
TgeneBPTFchr13:39613848chr17:65941525ENST000003218922130390_43723593047.0Zinc fingerPHD-type 1
TgeneBPTFchr13:39613848chr17:65941525ENST000003352212130390_43723592904.0Zinc fingerPHD-type 1


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Fusion Gene Sequence for NHLRC3-BPTF


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>59074_59074_1_NHLRC3-BPTF_NHLRC3_chr13_39613848_ENST00000379599_BPTF_chr17_65941525_ENST00000306378_length(transcript)=3562nt_BP=634nt
ACCTGACATGAGGGCGGGGACCCCGAAATGCACACGAAGTCCGGAACTGGTCTTCTGTGATTTTCATTCGCCCTGGTCTCTGTTCCCTTT
CGTACTCAAAGCTCGTGCATCCAGGGAGGGGAAACCGGAGATAGGGTCTTCGGGCCCCGGGCAGACCCTCTGTGCCGCTGCAAACCGTTG
CAGCCTGAGGCTGTCAGGTCCTCCCCCAGACACCTGCGGACCCTCCCTCTCCTGGCTTCCCGTCTGGTCATGGCGAGATTCTGGGTCTGC
GTAGCCGGTGCTGGCTTCTTTCTTGCATTTTTGGTTTTGCATTCGCGTTTTTGTGGCTCTCCAGTTTTGAGGAACTTTACTTTTGCAGTT
TCCTGGAGAACTGAGAAAATTCTTTACCGGCTGGATGTGGGTTGGCCTAAGCACCCAGAATATTTTACCGGAACAACATTTTGTGTTGCA
GTTGACTCCCTCAATGGATTGGTTTACATAGGTCAAAGAGGGGATAACATCCCAAAGATATTAGTGTTCACAGAGGATGGATATTTCCTA
CGAGCCTGGAATTATACAGTTGACACACCTCATGGTATATTTGCAGCCAGTACTCTATATGAACAATCCGTCTGGATCACGGATGTAGGA
AGTGGTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGT
GTGGGTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAA
GTTCAGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAG
CCCCAAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGT
CCATCAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACATACATCT
CTTCAGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTACAGTCTTCAACTCAAACTCTTTCATCAGGACAAACTTTAAATCAA
GTTACTGTTTCATCCCCATCCCGTCCTCAGCTACAAATACAGCAGCCACAGCCCCAAGTCATTGCTGTGCCTCAGCTGCAACAACAAGTC
CAGGTTCTCTCTCAGATCCAGTCACAGGTTGTGGCTCAGATACAGGCTCAGCAAAGTGGTGTGCCCCAGCAAATCAAACTCCAGTTACCT
ATCCAAATTCAGCAAAGCAGTGCTGTGCAGACTCACCAGATTCAGAATGTGGTTACAGTGCAGGCAGCCAGTGTGCAAGAGCAGTTGCAA
AGGGTTCAGCAACTCAGGGATCAGCAGCAAAAGAAGAAACAGCAACAGATAGAAATTAAGCGTGAACACACCCTCCAAGCTTCTAATCAA
AGTGAAATCATTCAGAAACAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGA
GAAGAGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAA
CGGAAGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTC
AGAGCCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTAAG
AAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCC
CCTCCACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAG
CGGGAAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTT
TACTGTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGC
ATCTTGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTA
ACAGAGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGACCCT
AATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAG
CTGACGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAA
GTTCTCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGTCTACAGCTTCTTAAAGT
TCAGCGTGTTAACCTAACATAAAACACAGCAAGAATCTGGTTGTCTGAACTATTTTAAATTAAGGAGCCAGATGTTTTTAGTCAGGCTAT
CCTGACAAGACTTGACCTAAACTTCGTTTTTATTGGTCATAACAGTCCAATTATATTCTTGGCCAATTTTGTCCAACGGACAAGAAAAAA
GCAAAGTCAACGACACCATTATCTTGTCAAGATCAGATGGTTTTACTATTGTGGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAAAAAG
AAAAAGAAAGCAAGAAAAAAAGATACTATGGGGTCAAGTGTAACTCCATGGAAATGCCACGTCTGCTCTTCAGTGAAGAAGCTGGTTTAG
AGTCTCACAGAAAACTTTTGACTGTATTTATTTATTGTTGCAAAAAAGACGCTTTTTTATTGCTGCCCTCATTTGTCAGCTAATTATTTT
TTCTTATAAAATCCAGCCCCGGTTACATATAATCATCTGTATCTTATCATGATTCCTGTAGGTAAAAGTACAAGACGACCTCTAGATGTC
TTTTCTTTCTATGAAAGGAGCTGCTATGTACACATGTGCACACACACACAACTGGGAATCAACAATGAGTTTATTGTTCATGGTAGATTA
AAATTAAGCTTGCATAAAGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTGTTGCCTTGAATATAACAGTACAATTTGTCAATTACTCT
GCACCAGGCTAAAATGAGTAAAATCTATTTGAAGGTATCTTGTTTGTAAACATTTGTCAGATTCTAATTTTTTTCTTTTGTATTAAAATT

>59074_59074_1_NHLRC3-BPTF_NHLRC3_chr13_39613848_ENST00000379599_BPTF_chr17_65941525_ENST00000306378_length(amino acids)=874AA_BP=187
MVSVPFRTQSSCIQGGETGDRVFGPRADPLCRCKPLQPEAVRSSPRHLRTLPLLASRLVMARFWVCVAGAGFFLAFLVLHSRFCGSPVLR
NFTFAVSWRTEKILYRLDVGWPKHPEYFTGTTFCVAVDSLNGLVYIGQRGDNIPKILVFTEDGYFLRAWNYTVDTPHGIFAASTLYEQSV
WITDVGSGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPT
HAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSS
GQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAAS
VQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEE
KQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPA
PPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWY
HGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQ

--------------------------------------------------------------
>59074_59074_2_NHLRC3-BPTF_NHLRC3_chr13_39613848_ENST00000379599_BPTF_chr17_65941525_ENST00000321892_length(transcript)=4787nt_BP=634nt
ACCTGACATGAGGGCGGGGACCCCGAAATGCACACGAAGTCCGGAACTGGTCTTCTGTGATTTTCATTCGCCCTGGTCTCTGTTCCCTTT
CGTACTCAAAGCTCGTGCATCCAGGGAGGGGAAACCGGAGATAGGGTCTTCGGGCCCCGGGCAGACCCTCTGTGCCGCTGCAAACCGTTG
CAGCCTGAGGCTGTCAGGTCCTCCCCCAGACACCTGCGGACCCTCCCTCTCCTGGCTTCCCGTCTGGTCATGGCGAGATTCTGGGTCTGC
GTAGCCGGTGCTGGCTTCTTTCTTGCATTTTTGGTTTTGCATTCGCGTTTTTGTGGCTCTCCAGTTTTGAGGAACTTTACTTTTGCAGTT
TCCTGGAGAACTGAGAAAATTCTTTACCGGCTGGATGTGGGTTGGCCTAAGCACCCAGAATATTTTACCGGAACAACATTTTGTGTTGCA
GTTGACTCCCTCAATGGATTGGTTTACATAGGTCAAAGAGGGGATAACATCCCAAAGATATTAGTGTTCACAGAGGATGGATATTTCCTA
CGAGCCTGGAATTATACAGTTGACACACCTCATGGTATATTTGCAGCCAGTACTCTATATGAACAATCCGTCTGGATCACGGATGTAGGA
AGTGGTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGT
GTGGGTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAA
GTTCAGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAG
CCCCAAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGT
CCATCAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACATACATCT
CTTCAGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTACAGTCTTCAACTCAAACTCTTTCATCAGGACAAACTTTAAATCAA
GTTACTGTTTCATCCCCATCCCGTCCTCAGCTACAAATACAGCAGCCACAGCCCCAAGTCATTGCTGTGCCTCAGCTGCAACAACAAGTC
CAGGTTCTCTCTCAGATCCAGTCACAGGTTGTGGCTCAGATACAGGCTCAGCAAAGTGGTGTGCCCCAGCAAATCAAACTCCAGTTACCT
ATCCAAATTCAGCAAAGCAGTGCTGTGCAGACTCACCAGATTCAGAATGTGGTTACAGTGCAGGCAGCCAGTGTGCAAGAGCAGTTGCAA
AGGGTTCAGCAACTCAGGGATCAGCAGCAAAAGAAGAAACAGCAACAGATAGAAATTAAGCGTGAACACACCCTCCAAGCTTCTAATCAA
AGTGAAATCATTCAGAAACAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGA
GAAGAGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAA
CGGAAGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTC
AGAGCCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTAAG
AAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCC
CCTCCACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAG
CGGGAAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTT
TACTGTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGC
ATCTTGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTA
ACAGAGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGACCCT
AATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAG
CTGACGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAA
GTTCTCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGTCTACAGCTTCTTAAAGT
TCAGCGTGTTAACCTAACATAAAACACAGCAAGAATCTGGTTGTCTGAACTATTTTAAATTAAGGAGCCAGATGTTTTTAGTCAGGCTAT
CCTGACAAGACTTGACCTAAACTTCGTTTTTATTGGTCATAACAGTCCAATTATATTCTTGGCCAATTTTGTCCAACGGACAAGAAAAAA
GCAAAGTCAACGACACCATTATCTTGTCAAGATCAGATGGTTTTACTATTGTGGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAAAAAG
AAAAAGAAAGCAAGAAAAAAAGATACTATGGGGTCAAGTGTAACTCCATGGAAATGCCACGTCTGCTCTTCAGTGAAGAAGCTGGTTTAG
AGTCTCACAGAAAACTTTTGACTGTATTTATTTATTGTTGCAAAAAAGACGCTTTTTTATTGCTGCCCTCATTTGTCAGCTAATTATTTT
TTCTTATAAAATCCAGCCCCGGTTACATATAATCATCTGTATCTTATCATGATTCCTGTAGGTAAAAGTACAAGACGACCTCTAGATGTC
TTTTCTTTCTATGAAAGGAGCTGCTATGTACACATGTGCACACACACACAACTGGGAATCAACAATGAGTTTATTGTTCATGGTAGATTA
AAATTAAGCTTGCATAAAGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTGTTGCCTTGAATATAACAGTACAATTTGTCAATTACTCT
GCACCAGGCTAAAATGAGTAAAATCTATTTGAAGGTATCTTGTTTGTAAACATTTGTCAGATTCTAATTTTTTTCTTTTGTATTAAAATT
CAACTATGGATGTATATGAAACAAAATAAATGGAGATAATTTTTCTCCCACAGACAGAGGTGTCTTTGAATGTGCGCTAATGATTATCTG
TAAGCCTTTGTGGGGAGGGAGGCCTGCAAGGTCATGAAAGGCAGAAGAGTCTAATTGTGCCTGGATTTCTCCAGGACAGCAGTGGCCCCT
CGTTTTATCATTCCCAGTCCATTGTCATCACGTCAGAGAAAAATCTTCAGGGGTGCTAATCCTGTTGCATCAGTTGATCATACTAACGAG
AACGGTAATGCGACAAGATACACATTGCCTTCATCTGTACATTCTGTGATACCAGGCAAATTACCAATTACACACAGCTACTTATATTTT
ATGAAGGGCATTTTTTAGATGACCTCATCCTCTGTGTTATTTGTTGATTGGGTTTGTTTTCTGTTTGTTGGTTTGTTTGTTTCTTCCACG
TAAGGAAAAGTAGTGTAAACAGTAGCGAGAAAATGGAAACCACAGAGGAAGATGTATTTTGCATGTTTTTCCTTTCAGTGTTCTTACACG
TTGTATCACTGCATTGTGGTAATAGCTTCTATAAAATCTGCCATAGTTGGATTATGCAGCTTTGCAAAAATTTTTACTAGATTTTGCACT
AACTCATATTAGCTTTGTCCTACCAACTTCTGGAATTTATCTAATTATTGTTTTTCAAAGTTTCTTTCCTTTTAATGTTTCCCTGCTATG
CAAAACCTTTCCCAGACCTCAGTTTCTTAAAAGAAAGATGTTGCTACAGTTCCCGATTCTTTCTTATTACAGGCTCAGGTGTACAGGTTA
TTCTGGGTTAATTTTATCTAATGAAGCCCATTCCTTTTTGTACATAAAGATGTCACTTAAACTTATGCTTACAAACTAAAGACTAATCGC
TCAATATGAAAACATGAAAAAATTTTTGCTTAAAGTATTAAGATGGAAGTAGTTAAATATGGGTTATTTTGTCCTTTTACTTTTTTAAAA
AATGTTACATATTGTATGCACTGTGCTGATGCAAGAATTCTACATTTTAATGAGTTATAAAATTATTCTGCATCTCATCACGTCACAGTA
TTTCTGTACTATTTATTCATATATATAAATATATATGGGCTTAATCATTTAAAATTTGTTGCAGCAAGAACTTTCCTACCTGTAGGCAAT
AGATTGCTATGTTTTTAACAAATTGTGGCAAATTCTAAACAGCAATTCTTTTGTACGTAATAGGACATTTCATCCTAGAAAAATAAAGTA

>59074_59074_2_NHLRC3-BPTF_NHLRC3_chr13_39613848_ENST00000379599_BPTF_chr17_65941525_ENST00000321892_length(amino acids)=874AA_BP=187
MVSVPFRTQSSCIQGGETGDRVFGPRADPLCRCKPLQPEAVRSSPRHLRTLPLLASRLVMARFWVCVAGAGFFLAFLVLHSRFCGSPVLR
NFTFAVSWRTEKILYRLDVGWPKHPEYFTGTTFCVAVDSLNGLVYIGQRGDNIPKILVFTEDGYFLRAWNYTVDTPHGIFAASTLYEQSV
WITDVGSGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPT
HAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSS
GQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAAS
VQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEE
KQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPA
PPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWY
HGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQ

--------------------------------------------------------------
>59074_59074_3_NHLRC3-BPTF_NHLRC3_chr13_39613848_ENST00000379599_BPTF_chr17_65941525_ENST00000335221_length(transcript)=4358nt_BP=634nt
ACCTGACATGAGGGCGGGGACCCCGAAATGCACACGAAGTCCGGAACTGGTCTTCTGTGATTTTCATTCGCCCTGGTCTCTGTTCCCTTT
CGTACTCAAAGCTCGTGCATCCAGGGAGGGGAAACCGGAGATAGGGTCTTCGGGCCCCGGGCAGACCCTCTGTGCCGCTGCAAACCGTTG
CAGCCTGAGGCTGTCAGGTCCTCCCCCAGACACCTGCGGACCCTCCCTCTCCTGGCTTCCCGTCTGGTCATGGCGAGATTCTGGGTCTGC
GTAGCCGGTGCTGGCTTCTTTCTTGCATTTTTGGTTTTGCATTCGCGTTTTTGTGGCTCTCCAGTTTTGAGGAACTTTACTTTTGCAGTT
TCCTGGAGAACTGAGAAAATTCTTTACCGGCTGGATGTGGGTTGGCCTAAGCACCCAGAATATTTTACCGGAACAACATTTTGTGTTGCA
GTTGACTCCCTCAATGGATTGGTTTACATAGGTCAAAGAGGGGATAACATCCCAAAGATATTAGTGTTCACAGAGGATGGATATTTCCTA
CGAGCCTGGAATTATACAGTTGACACACCTCATGGTATATTTGCAGCCAGTACTCTATATGAACAATCCGTCTGGATCACGGATGTAGGA
AGTGGTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGT
GTGGGTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAA
GTTCAGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAG
CCCCAAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGT
CCATCAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACATACATCT
CTTCAGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAG
AGCATGACTCCAGCTGAAAGAGAAGAGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAA
GAAAAACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTC
TTCAAGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTG
AAGAGAGACCTGAAAATTAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCA
GCTCCTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCT
GCTGCTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAA
ACTAAGAAGGACACAAAGCTTTACTGTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGG
TACCATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCC
ATGACAGTGCTCACGCCACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCT
TTCCTTGAACCAGTAGACCCTAATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTA
CAAAGACGATATTATGAAAAGCTGACGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCC
CCATTTTACCAGTGTGCAGAAGTTCTCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTG
CAGTCTACAGCTTCTTAAAGTTCAGCGTGTTAACCTAACATAAAACACAGCAAGAATCTGGTTGTCTGAACTATTTTAAATTAAGGAGCC
AGATGTTTTTAGTCAGGCTATCCTGACAAGACTTGACCTAAACTTCGTTTTTATTGGTCATAACAGTCCAATTATATTCTTGGCCAATTT
TGTCCAACGGACAAGAAAAAAGCAAAGTCAACGACACCATTATCTTGTCAAGATCAGATGGTTTTACTATTGTGGCAGAAGCGAGAAAAC
TTTGTTTATTGAAAAAAAAAGAAAAAGAAAGCAAGAAAAAAAGATACTATGGGGTCAAGTGTAACTCCATGGAAATGCCACGTCTGCTCT
TCAGTGAAGAAGCTGGTTTAGAGTCTCACAGAAAACTTTTGACTGTATTTATTTATTGTTGCAAAAAAGACGCTTTTTTATTGCTGCCCT
CATTTGTCAGCTAATTATTTTTTCTTATAAAATCCAGCCCCGGTTACATATAATCATCTGTATCTTATCATGATTCCTGTAGGTAAAAGT
ACAAGACGACCTCTAGATGTCTTTTCTTTCTATGAAAGGAGCTGCTATGTACACATGTGCACACACACACAACTGGGAATCAACAATGAG
TTTATTGTTCATGGTAGATTAAAATTAAGCTTGCATAAAGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTGTTGCCTTGAATATAACA
GTACAATTTGTCAATTACTCTGCACCAGGCTAAAATGAGTAAAATCTATTTGAAGGTATCTTGTTTGTAAACATTTGTCAGATTCTAATT
TTTTTCTTTTGTATTAAAATTCAACTATGGATGTATATGAAACAAAATAAATGGAGATAATTTTTCTCCCACAGACAGAGGTGTCTTTGA
ATGTGCGCTAATGATTATCTGTAAGCCTTTGTGGGGAGGGAGGCCTGCAAGGTCATGAAAGGCAGAAGAGTCTAATTGTGCCTGGATTTC
TCCAGGACAGCAGTGGCCCCTCGTTTTATCATTCCCAGTCCATTGTCATCACGTCAGAGAAAAATCTTCAGGGGTGCTAATCCTGTTGCA
TCAGTTGATCATACTAACGAGAACGGTAATGCGACAAGATACACATTGCCTTCATCTGTACATTCTGTGATACCAGGCAAATTACCAATT
ACACACAGCTACTTATATTTTATGAAGGGCATTTTTTAGATGACCTCATCCTCTGTGTTATTTGTTGATTGGGTTTGTTTTCTGTTTGTT
GGTTTGTTTGTTTCTTCCACGTAAGGAAAAGTAGTGTAAACAGTAGCGAGAAAATGGAAACCACAGAGGAAGATGTATTTTGCATGTTTT
TCCTTTCAGTGTTCTTACACGTTGTATCACTGCATTGTGGTAATAGCTTCTATAAAATCTGCCATAGTTGGATTATGCAGCTTTGCAAAA
ATTTTTACTAGATTTTGCACTAACTCATATTAGCTTTGTCCTACCAACTTCTGGAATTTATCTAATTATTGTTTTTCAAAGTTTCTTTCC
TTTTAATGTTTCCCTGCTATGCAAAACCTTTCCCAGACCTCAGTTTCTTAAAAGAAAGATGTTGCTACAGTTCCCGATTCTTTCTTATTA
CAGGCTCAGGTGTACAGGTTATTCTGGGTTAATTTTATCTAATGAAGCCCATTCCTTTTTGTACATAAAGATGTCACTTAAACTTATGCT
TACAAACTAAAGACTAATCGCTCAATATGAAAACATGAAAAAATTTTTGCTTAAAGTATTAAGATGGAAGTAGTTAAATATGGGTTATTT
TGTCCTTTTACTTTTTTAAAAAATGTTACATATTGTATGCACTGTGCTGATGCAAGAATTCTACATTTTAATGAGTTATAAAATTATTCT
GCATCTCATCACGTCACAGTATTTCTGTACTATTTATTCATATATATAAATATATATGGGCTTAATCATTTAAAATTTGTTGCAGCAAGA
ACTTTCCTACCTGTAGGCAATAGATTGCTATGTTTTTAACAAATTGTGGCAAATTCTAAACAGCAATTCTTTTGTACGTAATAGGACATT

>59074_59074_3_NHLRC3-BPTF_NHLRC3_chr13_39613848_ENST00000379599_BPTF_chr17_65941525_ENST00000335221_length(amino acids)=731AA_BP=187
MVSVPFRTQSSCIQGGETGDRVFGPRADPLCRCKPLQPEAVRSSPRHLRTLPLLASRLVMARFWVCVAGAGFFLAFLVLHSRFCGSPVLR
NFTFAVSWRTEKILYRLDVGWPKHPEYFTGTTFCVAVDSLNGLVYIGQRGDNIPKILVFTEDGYFLRAWNYTVDTPHGIFAASTLYEQSV
WITDVGSGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPT
HAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVVMKHNAVIE
HLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQI
EVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMI
STTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQA
HKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASR

--------------------------------------------------------------
>59074_59074_4_NHLRC3-BPTF_NHLRC3_chr13_39613848_ENST00000379599_BPTF_chr17_65941525_ENST00000424123_length(transcript)=2268nt_BP=634nt
ACCTGACATGAGGGCGGGGACCCCGAAATGCACACGAAGTCCGGAACTGGTCTTCTGTGATTTTCATTCGCCCTGGTCTCTGTTCCCTTT
CGTACTCAAAGCTCGTGCATCCAGGGAGGGGAAACCGGAGATAGGGTCTTCGGGCCCCGGGCAGACCCTCTGTGCCGCTGCAAACCGTTG
CAGCCTGAGGCTGTCAGGTCCTCCCCCAGACACCTGCGGACCCTCCCTCTCCTGGCTTCCCGTCTGGTCATGGCGAGATTCTGGGTCTGC
GTAGCCGGTGCTGGCTTCTTTCTTGCATTTTTGGTTTTGCATTCGCGTTTTTGTGGCTCTCCAGTTTTGAGGAACTTTACTTTTGCAGTT
TCCTGGAGAACTGAGAAAATTCTTTACCGGCTGGATGTGGGTTGGCCTAAGCACCCAGAATATTTTACCGGAACAACATTTTGTGTTGCA
GTTGACTCCCTCAATGGATTGGTTTACATAGGTCAAAGAGGGGATAACATCCCAAAGATATTAGTGTTCACAGAGGATGGATATTTCCTA
CGAGCCTGGAATTATACAGTTGACACACCTCATGGTATATTTGCAGCCAGTACTCTATATGAACAATCCGTCTGGATCACGGATGTAGGA
AGTGGTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGT
GTGGGTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAA
GTTCAGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAG
CCCCAAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGT
CCATCAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACATACATCT
CTTCAGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAG
AGCATGACTCCAGCTGAAAGAGAAGAGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAA
GAAAAACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTC
TTCAAGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTG
AAGAGAGACCTGAAAATTAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCA
GCTCCTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCT
GCTGCTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAA
ACTAAGAAGGACACAAAGCTTTACTGTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGG
TACCATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCC
ATGACAGTGCTCACGCCACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCT
TTCCTTGAACCAGTAGACCCTAATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTA
CAAAGACGATATTATGAAAAGCTGACGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCC
CCATTTTACCAGTGTGCAGAAGTTCTCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTG

>59074_59074_4_NHLRC3-BPTF_NHLRC3_chr13_39613848_ENST00000379599_BPTF_chr17_65941525_ENST00000424123_length(amino acids)=731AA_BP=187
MVSVPFRTQSSCIQGGETGDRVFGPRADPLCRCKPLQPEAVRSSPRHLRTLPLLASRLVMARFWVCVAGAGFFLAFLVLHSRFCGSPVLR
NFTFAVSWRTEKILYRLDVGWPKHPEYFTGTTFCVAVDSLNGLVYIGQRGDNIPKILVFTEDGYFLRAWNYTVDTPHGIFAASTLYEQSV
WITDVGSGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPT
HAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVVMKHNAVIE
HLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQI
EVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMI
STTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQA
HKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASR

--------------------------------------------------------------
>59074_59074_5_NHLRC3-BPTF_NHLRC3_chr13_39613848_ENST00000379600_BPTF_chr17_65941525_ENST00000306378_length(transcript)=3635nt_BP=707nt
GGTGGCCACTGAAAGTCAGCGGCGCGGACTGCCCTGAGGGCGGGAAAGGGTGGTCACTGGGTCAGCCCGAAGCACCTGACATGAGGGCGG
GGACCCCGAAATGCACACGAAGTCCGGAACTGGTCTTCTGTGATTTTCATTCGCCCTGGTCTCTGTTCCCTTTCGTACTCAAAGCTCGTG
CATCCAGGGAGGGGAAACCGGAGATAGGGTCTTCGGGCCCCGGGCAGACCCTCTGTGCCGCTGCAAACCGTTGCAGCCTGAGGCTGTCAG
GTCCTCCCCCAGACACCTGCGGACCCTCCCTCTCCTGGCTTCCCGTCTGGTCATGGCGAGATTCTGGGTCTGCGTAGCCGGTGCTGGCTT
CTTTCTTGCATTTTTGGTTTTGCATTCGCGTTTTTGTGGCTCTCCAGTTTTGAGGAACTTTACTTTTGCAGTTTCCTGGAGAACTGAGAA
AATTCTTTACCGGCTGGATGTGGGTTGGCCTAAGCACCCAGAATATTTTACCGGAACAACATTTTGTGTTGCAGTTGACTCCCTCAATGG
ATTGGTTTACATAGGTCAAAGAGGGGATAACATCCCAAAGATATTAGTGTTCACAGAGGATGGATATTTCCTACGAGCCTGGAATTATAC
AGTTGACACACCTCATGGTATATTTGCAGCCAGTACTCTATATGAACAATCCGTCTGGATCACGGATGTAGGAAGTGGTACAGGTGAACA
AAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGGGTCCAGCAGAAGC
CCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTCAGACTCAGCCTGA
AGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCCAAGTTGCAGCACA
GTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCATCAACTCCATCCCA
ACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTCAGATACCTTCCCA
AGGCCAGCCACAGTCACAACCCCAGGTACAGTCTTCAACTCAAACTCTTTCATCAGGACAAACTTTAAATCAAGTTACTGTTTCATCCCC
ATCCCGTCCTCAGCTACAAATACAGCAGCCACAGCCCCAAGTCATTGCTGTGCCTCAGCTGCAACAACAAGTCCAGGTTCTCTCTCAGAT
CCAGTCACAGGTTGTGGCTCAGATACAGGCTCAGCAAAGTGGTGTGCCCCAGCAAATCAAACTCCAGTTACCTATCCAAATTCAGCAAAG
CAGTGCTGTGCAGACTCACCAGATTCAGAATGTGGTTACAGTGCAGGCAGCCAGTGTGCAAGAGCAGTTGCAAAGGGTTCAGCAACTCAG
GGATCAGCAGCAAAAGAAGAAACAGCAACAGATAGAAATTAAGCGTGAACACACCCTCCAAGCTTCTAATCAAAGTGAAATCATTCAGAA
ACAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGAGAAGAGAATCAAAGAAT
GATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAG
TGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAA
GAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTAAGAAAGAAAAAGACCTGAT
GCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCC
CCCTCCACCTGCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGA
CTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTTTACTGTATCTGTAAAAC
GCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGC
AGAGCTCATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTAACAGAGAAGGATTATGA
GGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGACCCTAATGATGCACCAGATTA
TTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAGCTGACGGAATTTGTGGC
AGATATGACCAAAATTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTCTCGAATCATTCTT
TGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGTCTACAGCTTCTTAAAGTTCAGCGTGTTAACCTAA
CATAAAACACAGCAAGAATCTGGTTGTCTGAACTATTTTAAATTAAGGAGCCAGATGTTTTTAGTCAGGCTATCCTGACAAGACTTGACC
TAAACTTCGTTTTTATTGGTCATAACAGTCCAATTATATTCTTGGCCAATTTTGTCCAACGGACAAGAAAAAAGCAAAGTCAACGACACC
ATTATCTTGTCAAGATCAGATGGTTTTACTATTGTGGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAAAAAGAAAAAGAAAGCAAGAAA
AAAAGATACTATGGGGTCAAGTGTAACTCCATGGAAATGCCACGTCTGCTCTTCAGTGAAGAAGCTGGTTTAGAGTCTCACAGAAAACTT
TTGACTGTATTTATTTATTGTTGCAAAAAAGACGCTTTTTTATTGCTGCCCTCATTTGTCAGCTAATTATTTTTTCTTATAAAATCCAGC
CCCGGTTACATATAATCATCTGTATCTTATCATGATTCCTGTAGGTAAAAGTACAAGACGACCTCTAGATGTCTTTTCTTTCTATGAAAG
GAGCTGCTATGTACACATGTGCACACACACACAACTGGGAATCAACAATGAGTTTATTGTTCATGGTAGATTAAAATTAAGCTTGCATAA
AGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTGTTGCCTTGAATATAACAGTACAATTTGTCAATTACTCTGCACCAGGCTAAAATGA
GTAAAATCTATTTGAAGGTATCTTGTTTGTAAACATTTGTCAGATTCTAATTTTTTTCTTTTGTATTAAAATTCAACTATGGATGTATAT

>59074_59074_5_NHLRC3-BPTF_NHLRC3_chr13_39613848_ENST00000379600_BPTF_chr17_65941525_ENST00000306378_length(amino acids)=874AA_BP=187
MVSVPFRTQSSCIQGGETGDRVFGPRADPLCRCKPLQPEAVRSSPRHLRTLPLLASRLVMARFWVCVAGAGFFLAFLVLHSRFCGSPVLR
NFTFAVSWRTEKILYRLDVGWPKHPEYFTGTTFCVAVDSLNGLVYIGQRGDNIPKILVFTEDGYFLRAWNYTVDTPHGIFAASTLYEQSV
WITDVGSGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPT
HAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSS
GQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAAS
VQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEE
KQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPA
PPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWY
HGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQ

--------------------------------------------------------------
>59074_59074_6_NHLRC3-BPTF_NHLRC3_chr13_39613848_ENST00000379600_BPTF_chr17_65941525_ENST00000321892_length(transcript)=4860nt_BP=707nt
GGTGGCCACTGAAAGTCAGCGGCGCGGACTGCCCTGAGGGCGGGAAAGGGTGGTCACTGGGTCAGCCCGAAGCACCTGACATGAGGGCGG
GGACCCCGAAATGCACACGAAGTCCGGAACTGGTCTTCTGTGATTTTCATTCGCCCTGGTCTCTGTTCCCTTTCGTACTCAAAGCTCGTG
CATCCAGGGAGGGGAAACCGGAGATAGGGTCTTCGGGCCCCGGGCAGACCCTCTGTGCCGCTGCAAACCGTTGCAGCCTGAGGCTGTCAG
GTCCTCCCCCAGACACCTGCGGACCCTCCCTCTCCTGGCTTCCCGTCTGGTCATGGCGAGATTCTGGGTCTGCGTAGCCGGTGCTGGCTT
CTTTCTTGCATTTTTGGTTTTGCATTCGCGTTTTTGTGGCTCTCCAGTTTTGAGGAACTTTACTTTTGCAGTTTCCTGGAGAACTGAGAA
AATTCTTTACCGGCTGGATGTGGGTTGGCCTAAGCACCCAGAATATTTTACCGGAACAACATTTTGTGTTGCAGTTGACTCCCTCAATGG
ATTGGTTTACATAGGTCAAAGAGGGGATAACATCCCAAAGATATTAGTGTTCACAGAGGATGGATATTTCCTACGAGCCTGGAATTATAC
AGTTGACACACCTCATGGTATATTTGCAGCCAGTACTCTATATGAACAATCCGTCTGGATCACGGATGTAGGAAGTGGTACAGGTGAACA
AAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGGGTCCAGCAGAAGC
CCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTCAGACTCAGCCTGA
AGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCCAAGTTGCAGCACA
GTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCATCAACTCCATCCCA
ACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTCAGATACCTTCCCA
AGGCCAGCCACAGTCACAACCCCAGGTACAGTCTTCAACTCAAACTCTTTCATCAGGACAAACTTTAAATCAAGTTACTGTTTCATCCCC
ATCCCGTCCTCAGCTACAAATACAGCAGCCACAGCCCCAAGTCATTGCTGTGCCTCAGCTGCAACAACAAGTCCAGGTTCTCTCTCAGAT
CCAGTCACAGGTTGTGGCTCAGATACAGGCTCAGCAAAGTGGTGTGCCCCAGCAAATCAAACTCCAGTTACCTATCCAAATTCAGCAAAG
CAGTGCTGTGCAGACTCACCAGATTCAGAATGTGGTTACAGTGCAGGCAGCCAGTGTGCAAGAGCAGTTGCAAAGGGTTCAGCAACTCAG
GGATCAGCAGCAAAAGAAGAAACAGCAACAGATAGAAATTAAGCGTGAACACACCCTCCAAGCTTCTAATCAAAGTGAAATCATTCAGAA
ACAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGAGAAGAGAATCAAAGAAT
GATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAG
TGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAA
GAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTAAGAAAGAAAAAGACCTGAT
GCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCC
CCCTCCACCTGCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGA
CTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTTTACTGTATCTGTAAAAC
GCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGC
AGAGCTCATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTAACAGAGAAGGATTATGA
GGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGACCCTAATGATGCACCAGATTA
TTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAGCTGACGGAATTTGTGGC
AGATATGACCAAAATTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTCTCGAATCATTCTT
TGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGTCTACAGCTTCTTAAAGTTCAGCGTGTTAACCTAA
CATAAAACACAGCAAGAATCTGGTTGTCTGAACTATTTTAAATTAAGGAGCCAGATGTTTTTAGTCAGGCTATCCTGACAAGACTTGACC
TAAACTTCGTTTTTATTGGTCATAACAGTCCAATTATATTCTTGGCCAATTTTGTCCAACGGACAAGAAAAAAGCAAAGTCAACGACACC
ATTATCTTGTCAAGATCAGATGGTTTTACTATTGTGGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAAAAAGAAAAAGAAAGCAAGAAA
AAAAGATACTATGGGGTCAAGTGTAACTCCATGGAAATGCCACGTCTGCTCTTCAGTGAAGAAGCTGGTTTAGAGTCTCACAGAAAACTT
TTGACTGTATTTATTTATTGTTGCAAAAAAGACGCTTTTTTATTGCTGCCCTCATTTGTCAGCTAATTATTTTTTCTTATAAAATCCAGC
CCCGGTTACATATAATCATCTGTATCTTATCATGATTCCTGTAGGTAAAAGTACAAGACGACCTCTAGATGTCTTTTCTTTCTATGAAAG
GAGCTGCTATGTACACATGTGCACACACACACAACTGGGAATCAACAATGAGTTTATTGTTCATGGTAGATTAAAATTAAGCTTGCATAA
AGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTGTTGCCTTGAATATAACAGTACAATTTGTCAATTACTCTGCACCAGGCTAAAATGA
GTAAAATCTATTTGAAGGTATCTTGTTTGTAAACATTTGTCAGATTCTAATTTTTTTCTTTTGTATTAAAATTCAACTATGGATGTATAT
GAAACAAAATAAATGGAGATAATTTTTCTCCCACAGACAGAGGTGTCTTTGAATGTGCGCTAATGATTATCTGTAAGCCTTTGTGGGGAG
GGAGGCCTGCAAGGTCATGAAAGGCAGAAGAGTCTAATTGTGCCTGGATTTCTCCAGGACAGCAGTGGCCCCTCGTTTTATCATTCCCAG
TCCATTGTCATCACGTCAGAGAAAAATCTTCAGGGGTGCTAATCCTGTTGCATCAGTTGATCATACTAACGAGAACGGTAATGCGACAAG
ATACACATTGCCTTCATCTGTACATTCTGTGATACCAGGCAAATTACCAATTACACACAGCTACTTATATTTTATGAAGGGCATTTTTTA
GATGACCTCATCCTCTGTGTTATTTGTTGATTGGGTTTGTTTTCTGTTTGTTGGTTTGTTTGTTTCTTCCACGTAAGGAAAAGTAGTGTA
AACAGTAGCGAGAAAATGGAAACCACAGAGGAAGATGTATTTTGCATGTTTTTCCTTTCAGTGTTCTTACACGTTGTATCACTGCATTGT
GGTAATAGCTTCTATAAAATCTGCCATAGTTGGATTATGCAGCTTTGCAAAAATTTTTACTAGATTTTGCACTAACTCATATTAGCTTTG
TCCTACCAACTTCTGGAATTTATCTAATTATTGTTTTTCAAAGTTTCTTTCCTTTTAATGTTTCCCTGCTATGCAAAACCTTTCCCAGAC
CTCAGTTTCTTAAAAGAAAGATGTTGCTACAGTTCCCGATTCTTTCTTATTACAGGCTCAGGTGTACAGGTTATTCTGGGTTAATTTTAT
CTAATGAAGCCCATTCCTTTTTGTACATAAAGATGTCACTTAAACTTATGCTTACAAACTAAAGACTAATCGCTCAATATGAAAACATGA
AAAAATTTTTGCTTAAAGTATTAAGATGGAAGTAGTTAAATATGGGTTATTTTGTCCTTTTACTTTTTTAAAAAATGTTACATATTGTAT
GCACTGTGCTGATGCAAGAATTCTACATTTTAATGAGTTATAAAATTATTCTGCATCTCATCACGTCACAGTATTTCTGTACTATTTATT
CATATATATAAATATATATGGGCTTAATCATTTAAAATTTGTTGCAGCAAGAACTTTCCTACCTGTAGGCAATAGATTGCTATGTTTTTA
ACAAATTGTGGCAAATTCTAAACAGCAATTCTTTTGTACGTAATAGGACATTTCATCCTAGAAAAATAAAGTAATGTTTTTGACATTGGA

>59074_59074_6_NHLRC3-BPTF_NHLRC3_chr13_39613848_ENST00000379600_BPTF_chr17_65941525_ENST00000321892_length(amino acids)=874AA_BP=187
MVSVPFRTQSSCIQGGETGDRVFGPRADPLCRCKPLQPEAVRSSPRHLRTLPLLASRLVMARFWVCVAGAGFFLAFLVLHSRFCGSPVLR
NFTFAVSWRTEKILYRLDVGWPKHPEYFTGTTFCVAVDSLNGLVYIGQRGDNIPKILVFTEDGYFLRAWNYTVDTPHGIFAASTLYEQSV
WITDVGSGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPT
HAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSS
GQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAAS
VQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEE
KQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPA
PPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWY
HGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQ

--------------------------------------------------------------
>59074_59074_7_NHLRC3-BPTF_NHLRC3_chr13_39613848_ENST00000379600_BPTF_chr17_65941525_ENST00000335221_length(transcript)=4431nt_BP=707nt
GGTGGCCACTGAAAGTCAGCGGCGCGGACTGCCCTGAGGGCGGGAAAGGGTGGTCACTGGGTCAGCCCGAAGCACCTGACATGAGGGCGG
GGACCCCGAAATGCACACGAAGTCCGGAACTGGTCTTCTGTGATTTTCATTCGCCCTGGTCTCTGTTCCCTTTCGTACTCAAAGCTCGTG
CATCCAGGGAGGGGAAACCGGAGATAGGGTCTTCGGGCCCCGGGCAGACCCTCTGTGCCGCTGCAAACCGTTGCAGCCTGAGGCTGTCAG
GTCCTCCCCCAGACACCTGCGGACCCTCCCTCTCCTGGCTTCCCGTCTGGTCATGGCGAGATTCTGGGTCTGCGTAGCCGGTGCTGGCTT
CTTTCTTGCATTTTTGGTTTTGCATTCGCGTTTTTGTGGCTCTCCAGTTTTGAGGAACTTTACTTTTGCAGTTTCCTGGAGAACTGAGAA
AATTCTTTACCGGCTGGATGTGGGTTGGCCTAAGCACCCAGAATATTTTACCGGAACAACATTTTGTGTTGCAGTTGACTCCCTCAATGG
ATTGGTTTACATAGGTCAAAGAGGGGATAACATCCCAAAGATATTAGTGTTCACAGAGGATGGATATTTCCTACGAGCCTGGAATTATAC
AGTTGACACACCTCATGGTATATTTGCAGCCAGTACTCTATATGAACAATCCGTCTGGATCACGGATGTAGGAAGTGGTACAGGTGAACA
AAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGGGTCCAGCAGAAGC
CCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTCAGACTCAGCCTGA
AGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCCAAGTTGCAGCACA
GTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCATCAACTCCATCCCA
ACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTCAGATACCTTCCCA
AGGCCAGCCACAGTCACAACCCCAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCATGACTCCAGCTGA
AAGAGAAGAGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAAAACAGGCAGCAAA
AAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCA
GCTCAGAGCCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAAT
TAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCC
AGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAG
GAAGCGGGAAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTAAGAAGGACACAAA
GCTTTACTGTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACCATGGGCGCTGCGT
TGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGACAGTGCTCACGCC
ACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGA
CCCTAATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAAGACGATATTATGA
AAAGCTGACGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCATTTTACCAGTGTGC
AGAAGTTCTCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGTCTACAGCTTCTTA
AAGTTCAGCGTGTTAACCTAACATAAAACACAGCAAGAATCTGGTTGTCTGAACTATTTTAAATTAAGGAGCCAGATGTTTTTAGTCAGG
CTATCCTGACAAGACTTGACCTAAACTTCGTTTTTATTGGTCATAACAGTCCAATTATATTCTTGGCCAATTTTGTCCAACGGACAAGAA
AAAAGCAAAGTCAACGACACCATTATCTTGTCAAGATCAGATGGTTTTACTATTGTGGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAA
AAAGAAAAAGAAAGCAAGAAAAAAAGATACTATGGGGTCAAGTGTAACTCCATGGAAATGCCACGTCTGCTCTTCAGTGAAGAAGCTGGT
TTAGAGTCTCACAGAAAACTTTTGACTGTATTTATTTATTGTTGCAAAAAAGACGCTTTTTTATTGCTGCCCTCATTTGTCAGCTAATTA
TTTTTTCTTATAAAATCCAGCCCCGGTTACATATAATCATCTGTATCTTATCATGATTCCTGTAGGTAAAAGTACAAGACGACCTCTAGA
TGTCTTTTCTTTCTATGAAAGGAGCTGCTATGTACACATGTGCACACACACACAACTGGGAATCAACAATGAGTTTATTGTTCATGGTAG
ATTAAAATTAAGCTTGCATAAAGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTGTTGCCTTGAATATAACAGTACAATTTGTCAATTA
CTCTGCACCAGGCTAAAATGAGTAAAATCTATTTGAAGGTATCTTGTTTGTAAACATTTGTCAGATTCTAATTTTTTTCTTTTGTATTAA
AATTCAACTATGGATGTATATGAAACAAAATAAATGGAGATAATTTTTCTCCCACAGACAGAGGTGTCTTTGAATGTGCGCTAATGATTA
TCTGTAAGCCTTTGTGGGGAGGGAGGCCTGCAAGGTCATGAAAGGCAGAAGAGTCTAATTGTGCCTGGATTTCTCCAGGACAGCAGTGGC
CCCTCGTTTTATCATTCCCAGTCCATTGTCATCACGTCAGAGAAAAATCTTCAGGGGTGCTAATCCTGTTGCATCAGTTGATCATACTAA
CGAGAACGGTAATGCGACAAGATACACATTGCCTTCATCTGTACATTCTGTGATACCAGGCAAATTACCAATTACACACAGCTACTTATA
TTTTATGAAGGGCATTTTTTAGATGACCTCATCCTCTGTGTTATTTGTTGATTGGGTTTGTTTTCTGTTTGTTGGTTTGTTTGTTTCTTC
CACGTAAGGAAAAGTAGTGTAAACAGTAGCGAGAAAATGGAAACCACAGAGGAAGATGTATTTTGCATGTTTTTCCTTTCAGTGTTCTTA
CACGTTGTATCACTGCATTGTGGTAATAGCTTCTATAAAATCTGCCATAGTTGGATTATGCAGCTTTGCAAAAATTTTTACTAGATTTTG
CACTAACTCATATTAGCTTTGTCCTACCAACTTCTGGAATTTATCTAATTATTGTTTTTCAAAGTTTCTTTCCTTTTAATGTTTCCCTGC
TATGCAAAACCTTTCCCAGACCTCAGTTTCTTAAAAGAAAGATGTTGCTACAGTTCCCGATTCTTTCTTATTACAGGCTCAGGTGTACAG
GTTATTCTGGGTTAATTTTATCTAATGAAGCCCATTCCTTTTTGTACATAAAGATGTCACTTAAACTTATGCTTACAAACTAAAGACTAA
TCGCTCAATATGAAAACATGAAAAAATTTTTGCTTAAAGTATTAAGATGGAAGTAGTTAAATATGGGTTATTTTGTCCTTTTACTTTTTT
AAAAAATGTTACATATTGTATGCACTGTGCTGATGCAAGAATTCTACATTTTAATGAGTTATAAAATTATTCTGCATCTCATCACGTCAC
AGTATTTCTGTACTATTTATTCATATATATAAATATATATGGGCTTAATCATTTAAAATTTGTTGCAGCAAGAACTTTCCTACCTGTAGG
CAATAGATTGCTATGTTTTTAACAAATTGTGGCAAATTCTAAACAGCAATTCTTTTGTACGTAATAGGACATTTCATCCTAGAAAAATAA

>59074_59074_7_NHLRC3-BPTF_NHLRC3_chr13_39613848_ENST00000379600_BPTF_chr17_65941525_ENST00000335221_length(amino acids)=731AA_BP=187
MVSVPFRTQSSCIQGGETGDRVFGPRADPLCRCKPLQPEAVRSSPRHLRTLPLLASRLVMARFWVCVAGAGFFLAFLVLHSRFCGSPVLR
NFTFAVSWRTEKILYRLDVGWPKHPEYFTGTTFCVAVDSLNGLVYIGQRGDNIPKILVFTEDGYFLRAWNYTVDTPHGIFAASTLYEQSV
WITDVGSGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPT
HAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVVMKHNAVIE
HLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQI
EVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMI
STTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQA
HKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASR

--------------------------------------------------------------
>59074_59074_8_NHLRC3-BPTF_NHLRC3_chr13_39613848_ENST00000379600_BPTF_chr17_65941525_ENST00000424123_length(transcript)=2341nt_BP=707nt
GGTGGCCACTGAAAGTCAGCGGCGCGGACTGCCCTGAGGGCGGGAAAGGGTGGTCACTGGGTCAGCCCGAAGCACCTGACATGAGGGCGG
GGACCCCGAAATGCACACGAAGTCCGGAACTGGTCTTCTGTGATTTTCATTCGCCCTGGTCTCTGTTCCCTTTCGTACTCAAAGCTCGTG
CATCCAGGGAGGGGAAACCGGAGATAGGGTCTTCGGGCCCCGGGCAGACCCTCTGTGCCGCTGCAAACCGTTGCAGCCTGAGGCTGTCAG
GTCCTCCCCCAGACACCTGCGGACCCTCCCTCTCCTGGCTTCCCGTCTGGTCATGGCGAGATTCTGGGTCTGCGTAGCCGGTGCTGGCTT
CTTTCTTGCATTTTTGGTTTTGCATTCGCGTTTTTGTGGCTCTCCAGTTTTGAGGAACTTTACTTTTGCAGTTTCCTGGAGAACTGAGAA
AATTCTTTACCGGCTGGATGTGGGTTGGCCTAAGCACCCAGAATATTTTACCGGAACAACATTTTGTGTTGCAGTTGACTCCCTCAATGG
ATTGGTTTACATAGGTCAAAGAGGGGATAACATCCCAAAGATATTAGTGTTCACAGAGGATGGATATTTCCTACGAGCCTGGAATTATAC
AGTTGACACACCTCATGGTATATTTGCAGCCAGTACTCTATATGAACAATCCGTCTGGATCACGGATGTAGGAAGTGGTACAGGTGAACA
AAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGGGTCCAGCAGAAGC
CCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTCAGACTCAGCCTGA
AGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCCAAGTTGCAGCACA
GTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCATCAACTCCATCCCA
ACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTCAGATACCTTCCCA
AGGCCAGCCACAGTCACAACCCCAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCATGACTCCAGCTGA
AAGAGAAGAGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAAAACAGGCAGCAAA
AAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCA
GCTCAGAGCCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAAT
TAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCC
AGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAG
GAAGCGGGAAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTAAGAAGGACACAAA
GCTTTACTGTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACCATGGGCGCTGCGT
TGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGACAGTGCTCACGCC
ACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGA
CCCTAATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAAGACGATATTATGA
AAAGCTGACGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCATTTTACCAGTGTGC
AGAAGTTCTCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGTCTACAGCTTCTTA

>59074_59074_8_NHLRC3-BPTF_NHLRC3_chr13_39613848_ENST00000379600_BPTF_chr17_65941525_ENST00000424123_length(amino acids)=732AA_BP=187
MVSVPFRTQSSCIQGGETGDRVFGPRADPLCRCKPLQPEAVRSSPRHLRTLPLLASRLVMARFWVCVAGAGFFLAFLVLHSRFCGSPVLR
NFTFAVSWRTEKILYRLDVGWPKHPEYFTGTTFCVAVDSLNGLVYIGQRGDNIPKILVFTEDGYFLRAWNYTVDTPHGIFAASTLYEQSV
WITDVGSGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPT
HAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVVMKHNAVIE
HLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQI
EVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMI
STTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQA
HKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASR

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Fusion Gene PPI Analysis for NHLRC3-BPTF


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneBPTFchr13:39613848chr17:65941525ENST000003063781928640_7492233.33333333333352921.0KEAP1
TgeneBPTFchr13:39613848chr17:65941525ENST000003218922130640_7492359.33333333333353047.0KEAP1
TgeneBPTFchr13:39613848chr17:65941525ENST000003352212130640_7492359.33333333333352904.0KEAP1
TgeneBPTFchr13:39613848chr17:65941525ENST000003063781928839_9212233.33333333333352921.0MAZ
TgeneBPTFchr13:39613848chr17:65941525ENST000003218922130839_9212359.33333333333353047.0MAZ
TgeneBPTFchr13:39613848chr17:65941525ENST000003352212130839_9212359.33333333333352904.0MAZ


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NHLRC3-BPTF


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NHLRC3-BPTF


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0005684Malignant neoplasm of urinary bladder1CTD_human
TgeneC0005695Bladder Neoplasm1CTD_human
TgeneC3714756Intellectual Disability1GENOMICS_ENGLAND
TgeneC4540327NEURODEVELOPMENTAL DISORDER WITH DYSMORPHIC FACIES AND DISTAL LIMB ANOMALIES1GENOMICS_ENGLAND;UNIPROT