Fusion Gene Studies
in Kim Lab

FusionBase FusionGDB FusionGDB2 FusionPDB FusionNeoAntigen FusionAI FusionNW FGviewer Publication Contact
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact

Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:FAM102A-NAIF1 (FusionGDB2 ID:HG399665TG203245)

Fusion Gene Summary for FAM102A-NAIF1

check button Fusion gene summary
Fusion gene informationFusion gene name: FAM102A-NAIF1
Fusion gene ID: hg399665tg203245
HgeneTgene
Gene symbol

FAM102A

NAIF1

Gene ID

399665

203245

Gene namefamily with sequence similarity 102 member Anuclear apoptosis inducing factor 1
SynonymsC9orf132|EEIG1|SYM-3A|bA203J24.7C9orf90|bA379C10.2
Cytomap('FAM102A')('NAIF1')

9q34.11

9q34.11

Type of geneprotein-codingprotein-coding
Descriptionprotein FAM102AC230093N12Rikearly estrogen-induced gene 1 proteinsym-3 homolog Anuclear apoptosis-inducing factor 1
Modification date2020032020200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000373084, ENST00000373095, 
ENST00000300434, 
Fusion gene scores* DoF score11 X 7 X 10=7701 X 1 X 1=1
# samples 162
** MAII scorelog2(16/770*10)=-2.2667865406949
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(2/1*10)=4.32192809488736
Context

PubMed: FAM102A [Title/Abstract] AND NAIF1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFAM102A(130715854)-NAIF1(130826179), # samples:1
FAM102A(130707928)-NAIF1(130826179), # samples:1
Anticipated loss of major functional domain due to fusion event.FAM102A-NAIF1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
FAM102A-NAIF1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
FAM102A-NAIF1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
FAM102A-NAIF1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
FAM102A-NAIF1 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneNAIF1

GO:0030308

negative regulation of cell growth

16378748

TgeneNAIF1

GO:1902108

regulation of mitochondrial membrane permeability involved in apoptotic process

16378748


check buttonFusion gene breakpoints across FAM102A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across NAIF1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A1FW-01AFAM102Achr9

130715854

-NAIF1chr9

130826179

-
ChimerDB4BRCATCGA-A8-A09A-01AFAM102Achr9

130707928

-NAIF1chr9

130826179

-


Top

Fusion Gene ORF analysis for FAM102A-NAIF1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000373084ENST00000488519FAM102Achr9

130707928

-NAIF1chr9

130826179

-
5CDS-5UTRENST00000373095ENST00000488519FAM102Achr9

130715854

-NAIF1chr9

130826179

-
5CDS-5UTRENST00000373095ENST00000488519FAM102Achr9

130707928

-NAIF1chr9

130826179

-
5UTR-3CDSENST00000300434ENST00000373078FAM102Achr9

130707928

-NAIF1chr9

130826179

-
5UTR-5UTRENST00000300434ENST00000488519FAM102Achr9

130707928

-NAIF1chr9

130826179

-
Frame-shiftENST00000373095ENST00000373078FAM102Achr9

130707928

-NAIF1chr9

130826179

-
In-frameENST00000373084ENST00000373078FAM102Achr9

130707928

-NAIF1chr9

130826179

-
In-frameENST00000373095ENST00000373078FAM102Achr9

130715854

-NAIF1chr9

130826179

-
intron-3CDSENST00000300434ENST00000373078FAM102Achr9

130715854

-NAIF1chr9

130826179

-
intron-3CDSENST00000373084ENST00000373078FAM102Achr9

130715854

-NAIF1chr9

130826179

-
intron-5UTRENST00000300434ENST00000488519FAM102Achr9

130715854

-NAIF1chr9

130826179

-
intron-5UTRENST00000373084ENST00000488519FAM102Achr9

130715854

-NAIF1chr9

130826179

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000373095FAM102Achr9130715854-ENST00000373078NAIF1chr9130826179-33416736151145176
ENST00000373084FAM102Achr9130707928-ENST00000373078NAIF1chr9130826179-32756071831079298

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000373095ENST00000373078FAM102Achr9130715854-NAIF1chr9130826179-0.26399860.7360014
ENST00000373084ENST00000373078FAM102Achr9130707928-NAIF1chr9130826179-0.0092264320.99077356

Top

Fusion Genomic Features for FAM102A-NAIF1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

Top

Fusion Protein Features for FAM102A-NAIF1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:130715854/chr9:130826179)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFAM102Achr9:130707928chr9:130826179ENST00000373095-7112_145240385.0DomainC2 NT-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFAM102Achr9:130707928chr9:130826179ENST00000373084-48157_26898243.0Compositional biasNote=Ser-rich
HgeneFAM102Achr9:130707928chr9:130826179ENST00000373095-711157_268240385.0Compositional biasNote=Ser-rich
HgeneFAM102Achr9:130715854chr9:130826179ENST00000373084-18157_2680243.0Compositional biasNote=Ser-rich
HgeneFAM102Achr9:130715854chr9:130826179ENST00000373095-311157_26899385.0Compositional biasNote=Ser-rich
HgeneFAM102Achr9:130707928chr9:130826179ENST00000373084-482_14598243.0DomainC2 NT-type
HgeneFAM102Achr9:130715854chr9:130826179ENST00000373084-182_1450243.0DomainC2 NT-type
HgeneFAM102Achr9:130715854chr9:130826179ENST00000373095-3112_14599385.0DomainC2 NT-type
TgeneNAIF1chr9:130707928chr9:130826179ENST000003730780292_117170328.0Compositional biasNote=Gly-rich
TgeneNAIF1chr9:130715854chr9:130826179ENST000003730780292_117170328.0Compositional biasNote=Gly-rich
TgeneNAIF1chr9:130707928chr9:130826179ENST00000373078021_70170328.0RegionNote=Required for nuclear localization and apoptosis-inducing activity
TgeneNAIF1chr9:130715854chr9:130826179ENST00000373078021_70170328.0RegionNote=Required for nuclear localization and apoptosis-inducing activity


Top

Fusion Gene Sequence for FAM102A-NAIF1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>28289_28289_1_FAM102A-NAIF1_FAM102A_chr9_130707928_ENST00000373084_NAIF1_chr9_130826179_ENST00000373078_length(transcript)=3275nt_BP=607nt
GCTGCCGACCCGGGGCCTCTGTCCTTGGGTCCCAGTTATGCAACAGTCAGTCGAGGCTGTGGGGCTGGCCCAGGGGCTTTATCTGTCTCC
CTCTCCAACTTTTGCCAAGTTACCCTTCTGGGCTTCCGCCAGCCAGGAGCCCACACTCCCTCAGCCCTCCCACACGCTCCTCTCACCTCC
TAGCTGGGCTTCGCTGACTTGAACCTGGCCGAGTTTGCGGGCTCGGGCTCCACGGTGCGCTGCTGCCTGCTCGAGGGATATGACACGAAG
AACACTCGCCAGGACAACTCCATCCTTAAGGTCACCATTGGTATGTTCCTGCTCTCTGGAGATCCCTGCTTCAAGACGCCACCATCGACT
GCCAAGTCCATCTCCATCCCAGGCCAGGATTCCTCCCTGCAGCTGACGTGTAAGGGTGGTGGGACCAGCAGTGGGGGCAGCAGCACCAAC
TCCCTGACTGGGTCCCGGCCCCCCAAGGCTCGGCCCACTATTCTCAGCTCAGGGCTGCCAGAGGAACCCGACCAGAACCTGTCCAGCCCT
GAGGAGGTGTTCCACTCTGGCCACTCCCGCAACTCCAGCTATGCCAGCCAGCAGTCCAAGATCTCCGTCCCCACAGAGACCACCTATCAC
ACGCTGGAGGAGGGCGTGGTGGAGTACTGCACGGCTGAGGCGCCCCCACCTCTGCCACCAGAGACCCCTGTGGACATGATGGCCCAGCAT
GCAGACACGTCGGTCAAGCCGCAAGCGCTCAAGAGCCGCATTGCTCTCAACTCCGCCAAGCTGATACAGGAGCAGCGGGTCACCAACCTG
CATGTGAAGGAGATCGCACAGCACCTGGAACAGCAGAACGACCTACTGCAGATGATCCGCCGCTCCCAGGAAGTGCAGGCCTGTGCCCAG
GAGCGCCAGGCCCAGGCCATGGAGGGCACACAGGCTGCCCTGAGCGTCCTCATCCAGGTCCTCCGGCCTATGATCAAAGATTTCCGCCGC
TACCTGCAGAGCAACACAGCTAACCCGGCCCCCGCCTCTGACCCTGGGCAGGTGGCCCAGAATGGGCAGCCAGACAGCATCATCCAGTGA
GGGCAGGGGTCAGGCCAGCCTTCTGCCATGATGGGATGAAAACTCCATGGACTTGTAAGTGGGTCCTGTGATTGGCCTTGGCCTTAGACC
GGCCACGTGCACAGCTCCCTCTTTAATAAACGCTTAGGGGTTGCACTGTTTTTGAGAAGAGGAATTTGTTGGGCTCCTGGGACCCAAACT
CATACTCCCCCTACTTGAGCTGCCTTGCTAAGATCCAGAAGATTGGTTAGCAGGGGGTCACGTGTGCATGTGATGGGACATGTGTTGTCA
TGACCCCGGGCTTGTGACATGACCCAGCCTTGGTCTTGGACAACTGTAAGGAACAACACAACGGGCTGTCACTGGGGGCCGTCACCCAGC
CTGGGTCTCTACTGAGCTGCCCAACCCCAGGTGCCATCCTTTCGAGTAGGGTAATGTCACTGATGCTGGCAGTTGAGCAATAATATCTTC
CTCCTTTGGGAGGTAGTGTGACTGAGGAGGAAACCCCACCCTTTTCTCCTCACTGTGCCTCAGTTCTCAGGGGACTCCAATGACTGTTGT
GCTCTCCCCCGACCCCACCCCAGGCACAGCGCAGGCCCTTGTTAGGTAGTGTGCTGGGACGCCTCCGTAATACATGCAGTGTGCAGCCAG
TCTGGCTCAGGAATGCTGTGTATGGTGGGGACGGTTTGGCCACTCTCTGGTTTTCAACAGCATCTCTGGGCAGCCCTTTGGTGGTTTGTC
CCTAGAGCTTTTGACTCAGGTCAAGCTTTGGATGCTGTAAATTTTTGAGAAAGCCAACTAGTGTGGAAGCTTGCTGCCCCACTGCAGTGG
GTCTGAGTGACCTGTTGGCTTTGTGCGGAGGCTTGCATCCAGCCAGTTGTATTTATTCTGTGTGTGAACCCCTCCTAGGAAGGCCTCCAG
GAAGGCTGCCCTGTGGCCACACCCATCCTCCTTTCCTCTCTGCTGACTCCACATTTCCAAAATTCAGTGCAAAAAAAGCCCTGCTGAGCA
TCACATGCTGGACTCTTCCCCTGCCACACCGCTCAGTGCCTTCTGTTCTCTTGAGACTCCCTCTGAGTAGCTGAGTGAATCCAAAGCCAT
AATTGACCCTGAACGTAGGAGGAGGAAAAGGCGAAGCTGACCTAAGAAGTGGGACCCTGGCCGGGCGAGGTGGCTCAAGTCTGTAATCCC
AGCGCTTTGGGAGGCCGAGGCGGGTGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGATGAAACCCCGTCTCTACTAAAA
ACACAAAAATTAGCTGGGCGTGGTGGCACACGCCTGTAGTCCCAGCTACCCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGC
GGAGATTGCAGTGAGCCGAGATTGCACCGCTGCACTCCAGCCTGGCGACAGAGCGAGACTCTGTCTCAAAAAAAAAACAAAGAAAAAACC
AAAAAAACAAATGGGACCCTTTGGATTCTATGCTCAGGGAAGAGCAGGCAGAGCCTTGGAGTGCTGAAGGAGGTGCTGTTCCCTGTTCCA
TCTTTACACTTTCTCTTCTGAGATGTCTGTAAGGATTTTACCCAGATGCCATTTGTCTGTTTCATTTTCAGACTCACCATCAATTACCAA
GGCCCTTGCATCTCCCCAGATCGTTTCCCAAGTTTGGCGATTTGCTGTCGGTGCCTCAGCCACATATGACCAATGGTTACAACTCAGGGC
TCCAGACCTCAGCTAAAAAGAGAAGACGCTGCCCTCCTGGGCACGAACGTTTAGAATGCTCAACTCCTCTATTGTGACCACAGGAAGGTG
GCCCTGAAGATGCACCGAAGACAGCTGGGAGGTGACTGCTGTACTGTCAGCCTCTCTGTGGAGGCATTCGTGCAGTGCCAGCTAAAAGGG
AGGTGAAGGGGGATATCGGACCCAGCGAGGGAGTTGCTGGTAGAAGGAAAGCTCTTCTCAGTGTGGCTGGATTAAGAGCAGCCTAGCAGC
TTGGGCACCTCCACTCTGTGCGGTCTGATGGCCCCAGCAAGGTCGCTGCAGGGACTTCCTGAGGACTTGGTTTGGTTTTTTTCTGGGGTT
GGAAATCTGAGCCAATATTGTGTCTGTTCCATTTGGGTATGAAGAGGAAGTCTGGATCACTTAAACTGACTAGTTATTTCCGGGTCATAA

>28289_28289_1_FAM102A-NAIF1_FAM102A_chr9_130707928_ENST00000373084_NAIF1_chr9_130826179_ENST00000373078_length(amino acids)=298AA_BP=141
MGFADLNLAEFAGSGSTVRCCLLEGYDTKNTRQDNSILKVTIGMFLLSGDPCFKTPPSTAKSISIPGQDSSLQLTCKGGGTSSGGSSTNS
LTGSRPPKARPTILSSGLPEEPDQNLSSPEEVFHSGHSRNSSYASQQSKISVPTETTYHTLEEGVVEYCTAEAPPPLPPETPVDMMAQHA
DTSVKPQALKSRIALNSAKLIQEQRVTNLHVKEIAQHLEQQNDLLQMIRRSQEVQACAQERQAQAMEGTQAALSVLIQVLRPMIKDFRRY

--------------------------------------------------------------
>28289_28289_2_FAM102A-NAIF1_FAM102A_chr9_130715854_ENST00000373095_NAIF1_chr9_130826179_ENST00000373078_length(transcript)=3341nt_BP=673nt
CCGCGCGGCGTGAGCTCCCCGGACATCGCGTCTCGGGATGCTGCAAGCCAGCGCGGCCGCTCGCGCGCAGCCCCGCACCTCCGCCCCTGC
CTCTGCCTCCTGGGCCATGCCCTGCTGTTTACATGCCGGTGAGGTCCCCGGCCGCTCCGAACCCCTCCGAGCCCCGGCTCCCCGAGGGTG
AAGCCCGCCGGCCCGCGAACTGGACTGGTGGATCTCTCAGACCTGGGGCCCCGGACTCCGATCTCCGCCGTCTCCGCCACCATCAGGGCG
GGATCCGGCTCTGGTGTTTTGAGGAGGGGGTGTGGTGTAGGGAAAGGAATCCCGTCCCTCTCCACCTTTTTTCGCCTTCGGGGCTTCAGA
CTCAGGGAACTCGCTCATGGCTTTCTTGATGAAGAAGAAGAAATTCAAATTCCAAACTACTTTCACCCTGGAGGAGCTGACTGCGGTTCC
CTTCGTGAACGGGGTCCTCTTCTGCAAGGTCCGGCTGCTGGATGGAGGGGATTTTGTCAGCTTGTCGTCAAGGGAGGAGGTACAGGAGAA
CTGTGTGCGGTGGCGAAAGAGGTTCACCTTCGTGTGTAAGATGAGTGCTAACCCGGCCACCGGCCTGCTGGACCCCTGTGTCTTCCGTGT
GTCTGTGCGCAAGGAGCTGAAAGGCGGGAAGGCTTATTCCAAGTCCCCACAGAGACCACCTATCACACGCTGGAGGAGGGCGTGGTGGAG
TACTGCACGGCTGAGGCGCCCCCACCTCTGCCACCAGAGACCCCTGTGGACATGATGGCCCAGCATGCAGACACGTCGGTCAAGCCGCAA
GCGCTCAAGAGCCGCATTGCTCTCAACTCCGCCAAGCTGATACAGGAGCAGCGGGTCACCAACCTGCATGTGAAGGAGATCGCACAGCAC
CTGGAACAGCAGAACGACCTACTGCAGATGATCCGCCGCTCCCAGGAAGTGCAGGCCTGTGCCCAGGAGCGCCAGGCCCAGGCCATGGAG
GGCACACAGGCTGCCCTGAGCGTCCTCATCCAGGTCCTCCGGCCTATGATCAAAGATTTCCGCCGCTACCTGCAGAGCAACACAGCTAAC
CCGGCCCCCGCCTCTGACCCTGGGCAGGTGGCCCAGAATGGGCAGCCAGACAGCATCATCCAGTGAGGGCAGGGGTCAGGCCAGCCTTCT
GCCATGATGGGATGAAAACTCCATGGACTTGTAAGTGGGTCCTGTGATTGGCCTTGGCCTTAGACCGGCCACGTGCACAGCTCCCTCTTT
AATAAACGCTTAGGGGTTGCACTGTTTTTGAGAAGAGGAATTTGTTGGGCTCCTGGGACCCAAACTCATACTCCCCCTACTTGAGCTGCC
TTGCTAAGATCCAGAAGATTGGTTAGCAGGGGGTCACGTGTGCATGTGATGGGACATGTGTTGTCATGACCCCGGGCTTGTGACATGACC
CAGCCTTGGTCTTGGACAACTGTAAGGAACAACACAACGGGCTGTCACTGGGGGCCGTCACCCAGCCTGGGTCTCTACTGAGCTGCCCAA
CCCCAGGTGCCATCCTTTCGAGTAGGGTAATGTCACTGATGCTGGCAGTTGAGCAATAATATCTTCCTCCTTTGGGAGGTAGTGTGACTG
AGGAGGAAACCCCACCCTTTTCTCCTCACTGTGCCTCAGTTCTCAGGGGACTCCAATGACTGTTGTGCTCTCCCCCGACCCCACCCCAGG
CACAGCGCAGGCCCTTGTTAGGTAGTGTGCTGGGACGCCTCCGTAATACATGCAGTGTGCAGCCAGTCTGGCTCAGGAATGCTGTGTATG
GTGGGGACGGTTTGGCCACTCTCTGGTTTTCAACAGCATCTCTGGGCAGCCCTTTGGTGGTTTGTCCCTAGAGCTTTTGACTCAGGTCAA
GCTTTGGATGCTGTAAATTTTTGAGAAAGCCAACTAGTGTGGAAGCTTGCTGCCCCACTGCAGTGGGTCTGAGTGACCTGTTGGCTTTGT
GCGGAGGCTTGCATCCAGCCAGTTGTATTTATTCTGTGTGTGAACCCCTCCTAGGAAGGCCTCCAGGAAGGCTGCCCTGTGGCCACACCC
ATCCTCCTTTCCTCTCTGCTGACTCCACATTTCCAAAATTCAGTGCAAAAAAAGCCCTGCTGAGCATCACATGCTGGACTCTTCCCCTGC
CACACCGCTCAGTGCCTTCTGTTCTCTTGAGACTCCCTCTGAGTAGCTGAGTGAATCCAAAGCCATAATTGACCCTGAACGTAGGAGGAG
GAAAAGGCGAAGCTGACCTAAGAAGTGGGACCCTGGCCGGGCGAGGTGGCTCAAGTCTGTAATCCCAGCGCTTTGGGAGGCCGAGGCGGG
TGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGATGAAACCCCGTCTCTACTAAAAACACAAAAATTAGCTGGGCGTGGT
GGCACACGCCTGTAGTCCCAGCTACCCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCGGAGATTGCAGTGAGCCGAGATTG
CACCGCTGCACTCCAGCCTGGCGACAGAGCGAGACTCTGTCTCAAAAAAAAAACAAAGAAAAAACCAAAAAAACAAATGGGACCCTTTGG
ATTCTATGCTCAGGGAAGAGCAGGCAGAGCCTTGGAGTGCTGAAGGAGGTGCTGTTCCCTGTTCCATCTTTACACTTTCTCTTCTGAGAT
GTCTGTAAGGATTTTACCCAGATGCCATTTGTCTGTTTCATTTTCAGACTCACCATCAATTACCAAGGCCCTTGCATCTCCCCAGATCGT
TTCCCAAGTTTGGCGATTTGCTGTCGGTGCCTCAGCCACATATGACCAATGGTTACAACTCAGGGCTCCAGACCTCAGCTAAAAAGAGAA
GACGCTGCCCTCCTGGGCACGAACGTTTAGAATGCTCAACTCCTCTATTGTGACCACAGGAAGGTGGCCCTGAAGATGCACCGAAGACAG
CTGGGAGGTGACTGCTGTACTGTCAGCCTCTCTGTGGAGGCATTCGTGCAGTGCCAGCTAAAAGGGAGGTGAAGGGGGATATCGGACCCA
GCGAGGGAGTTGCTGGTAGAAGGAAAGCTCTTCTCAGTGTGGCTGGATTAAGAGCAGCCTAGCAGCTTGGGCACCTCCACTCTGTGCGGT
CTGATGGCCCCAGCAAGGTCGCTGCAGGGACTTCCTGAGGACTTGGTTTGGTTTTTTTCTGGGGTTGGAAATCTGAGCCAATATTGTGTC
TGTTCCATTTGGGTATGAAGAGGAAGTCTGGATCACTTAAACTGACTAGTTATTTCCGGGTCATAATTTTAAATTAAAGACATATCACTT

>28289_28289_2_FAM102A-NAIF1_FAM102A_chr9_130715854_ENST00000373095_NAIF1_chr9_130826179_ENST00000373078_length(amino acids)=176AA_BP=19
MCLPCVCAQGAERREGLFQVPTETTYHTLEEGVVEYCTAEAPPPLPPETPVDMMAQHADTSVKPQALKSRIALNSAKLIQEQRVTNLHVK

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for FAM102A-NAIF1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for FAM102A-NAIF1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for FAM102A-NAIF1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource