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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ARRB1-PRCP (FusionGDB2 ID:HG408TG5547)

Fusion Gene Summary for ARRB1-PRCP

check button Fusion gene summary
Fusion gene informationFusion gene name: ARRB1-PRCP
Fusion gene ID: hg408tg5547
HgeneTgene
Gene symbol

ARRB1

PRCP

Gene ID

408

5547

Gene namearrestin beta 1prolylcarboxypeptidase
SynonymsARB1|ARR1HUMPCP|PCP
Cytomap('ARRB1')('PRCP')

11q13.4

11q14.1

Type of geneprotein-codingprotein-coding
Descriptionbeta-arrestin-1arrestin 2non-visual arrestin-2lysosomal Pro-X carboxypeptidaseangiotensinase Clysosomal carboxypeptidase Cproline carboxypeptidase
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000360025, ENST00000393505, 
ENST00000420843, 
Fusion gene scores* DoF score18 X 10 X 9=16209 X 8 X 6=432
# samples 2311
** MAII scorelog2(23/1620*10)=-2.81628804682761
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/432*10)=-1.97352778863881
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ARRB1 [Title/Abstract] AND PRCP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointARRB1(75062632)-PRCP(82550467), # samples:2
Anticipated loss of major functional domain due to fusion event.ARRB1-PRCP seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARRB1-PRCP seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneARRB1

GO:0031397

negative regulation of protein ubiquitination

16378096

HgeneARRB1

GO:0032088

negative regulation of NF-kappaB transcription factor activity

16378096

HgeneARRB1

GO:0032715

negative regulation of interleukin-6 production

16378096

HgeneARRB1

GO:0032717

negative regulation of interleukin-8 production

16378096

HgeneARRB1

GO:0070374

positive regulation of ERK1 and ERK2 cascade

10644702


check buttonFusion gene breakpoints across ARRB1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across PRCP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-EE-A2GR-06AARRB1chr11

75062632

-PRCPchr11

82549616

-
ChimerDB4SKCMTCGA-EE-A2GR-06AARRB1chr11

75062632

-PRCPchr11

82550467

-


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Fusion Gene ORF analysis for ARRB1-PRCP

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000360025ENST00000525772ARRB1chr11

75062632

-PRCPchr11

82549616

-
5CDS-5UTRENST00000360025ENST00000525772ARRB1chr11

75062632

-PRCPchr11

82550467

-
5CDS-5UTRENST00000393505ENST00000525772ARRB1chr11

75062632

-PRCPchr11

82549616

-
5CDS-5UTRENST00000393505ENST00000525772ARRB1chr11

75062632

-PRCPchr11

82550467

-
5CDS-5UTRENST00000420843ENST00000525772ARRB1chr11

75062632

-PRCPchr11

82549616

-
5CDS-5UTRENST00000420843ENST00000525772ARRB1chr11

75062632

-PRCPchr11

82550467

-
In-frameENST00000360025ENST00000313010ARRB1chr11

75062632

-PRCPchr11

82549616

-
In-frameENST00000360025ENST00000313010ARRB1chr11

75062632

-PRCPchr11

82550467

-
In-frameENST00000360025ENST00000393399ARRB1chr11

75062632

-PRCPchr11

82549616

-
In-frameENST00000360025ENST00000393399ARRB1chr11

75062632

-PRCPchr11

82550467

-
In-frameENST00000360025ENST00000535099ARRB1chr11

75062632

-PRCPchr11

82549616

-
In-frameENST00000360025ENST00000535099ARRB1chr11

75062632

-PRCPchr11

82550467

-
In-frameENST00000393505ENST00000313010ARRB1chr11

75062632

-PRCPchr11

82549616

-
In-frameENST00000393505ENST00000313010ARRB1chr11

75062632

-PRCPchr11

82550467

-
In-frameENST00000393505ENST00000393399ARRB1chr11

75062632

-PRCPchr11

82549616

-
In-frameENST00000393505ENST00000393399ARRB1chr11

75062632

-PRCPchr11

82550467

-
In-frameENST00000393505ENST00000535099ARRB1chr11

75062632

-PRCPchr11

82549616

-
In-frameENST00000393505ENST00000535099ARRB1chr11

75062632

-PRCPchr11

82550467

-
In-frameENST00000420843ENST00000313010ARRB1chr11

75062632

-PRCPchr11

82549616

-
In-frameENST00000420843ENST00000313010ARRB1chr11

75062632

-PRCPchr11

82550467

-
In-frameENST00000420843ENST00000393399ARRB1chr11

75062632

-PRCPchr11

82549616

-
In-frameENST00000420843ENST00000393399ARRB1chr11

75062632

-PRCPchr11

82550467

-
In-frameENST00000420843ENST00000535099ARRB1chr11

75062632

-PRCPchr11

82549616

-
In-frameENST00000420843ENST00000535099ARRB1chr11

75062632

-PRCPchr11

82550467

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000420843ARRB1chr1175062632-ENST00000313010PRCPchr1182549616-192711816522168
ENST00000420843ARRB1chr1175062632-ENST00000393399PRCPchr1182549616-106111816522168
ENST00000420843ARRB1chr1175062632-ENST00000535099PRCPchr1182549616-63911816522168
ENST00000393505ARRB1chr1175062632-ENST00000313010PRCPchr1182549616-205124244646200
ENST00000393505ARRB1chr1175062632-ENST00000393399PRCPchr1182549616-118524244646200
ENST00000393505ARRB1chr1175062632-ENST00000535099PRCPchr1182549616-76324244646200
ENST00000360025ARRB1chr1175062632-ENST00000313010PRCPchr1182549616-192711816522168
ENST00000360025ARRB1chr1175062632-ENST00000393399PRCPchr1182549616-106111816522168
ENST00000360025ARRB1chr1175062632-ENST00000535099PRCPchr1182549616-63911816522168
ENST00000420843ARRB1chr1175062632-ENST00000313010PRCPchr1182550467-209211816687223
ENST00000420843ARRB1chr1175062632-ENST00000393399PRCPchr1182550467-122611816687223
ENST00000420843ARRB1chr1175062632-ENST00000535099PRCPchr1182550467-80411816687223
ENST00000393505ARRB1chr1175062632-ENST00000313010PRCPchr1182550467-221624244811255
ENST00000393505ARRB1chr1175062632-ENST00000393399PRCPchr1182550467-135024244811255
ENST00000393505ARRB1chr1175062632-ENST00000535099PRCPchr1182550467-92824244811255
ENST00000360025ARRB1chr1175062632-ENST00000313010PRCPchr1182550467-209211816687223
ENST00000360025ARRB1chr1175062632-ENST00000393399PRCPchr1182550467-122611816687223
ENST00000360025ARRB1chr1175062632-ENST00000535099PRCPchr1182550467-80411816687223

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000420843ENST00000313010ARRB1chr1175062632-PRCPchr1182549616-0.0610361920.93896383
ENST00000420843ENST00000393399ARRB1chr1175062632-PRCPchr1182549616-0.0554710140.94452894
ENST00000420843ENST00000535099ARRB1chr1175062632-PRCPchr1182549616-0.0178952480.9821047
ENST00000393505ENST00000313010ARRB1chr1175062632-PRCPchr1182549616-0.0232079360.97679204
ENST00000393505ENST00000393399ARRB1chr1175062632-PRCPchr1182549616-0.0284802520.97151977
ENST00000393505ENST00000535099ARRB1chr1175062632-PRCPchr1182549616-0.019896250.98010373
ENST00000360025ENST00000313010ARRB1chr1175062632-PRCPchr1182549616-0.0610361920.93896383
ENST00000360025ENST00000393399ARRB1chr1175062632-PRCPchr1182549616-0.0554710140.94452894
ENST00000360025ENST00000535099ARRB1chr1175062632-PRCPchr1182549616-0.0178952480.9821047
ENST00000420843ENST00000313010ARRB1chr1175062632-PRCPchr1182550467-0.0434987470.95650125
ENST00000420843ENST00000393399ARRB1chr1175062632-PRCPchr1182550467-0.0367364960.9632635
ENST00000420843ENST00000535099ARRB1chr1175062632-PRCPchr1182550467-0.0194028490.9805972
ENST00000393505ENST00000313010ARRB1chr1175062632-PRCPchr1182550467-0.0198715370.98012847
ENST00000393505ENST00000393399ARRB1chr1175062632-PRCPchr1182550467-0.0283746550.9716253
ENST00000393505ENST00000535099ARRB1chr1175062632-PRCPchr1182550467-0.0171219840.98287797
ENST00000360025ENST00000313010ARRB1chr1175062632-PRCPchr1182550467-0.0434987470.95650125
ENST00000360025ENST00000393399ARRB1chr1175062632-PRCPchr1182550467-0.0367364960.9632635
ENST00000360025ENST00000535099ARRB1chr1175062632-PRCPchr1182550467-0.0194028490.9805972

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Fusion Genomic Features for ARRB1-PRCP


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ARRB1-PRCP


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:75062632/chr11:82550467)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARRB1chr11:75062632chr11:82549616ENST00000360025-115385_3956411.0MotifNote=[DE]-X(1%2C2)-F-X-X-[FL]-X-X-X-R motif
HgeneARRB1chr11:75062632chr11:82549616ENST00000420843-116385_3956419.0MotifNote=[DE]-X(1%2C2)-F-X-X-[FL]-X-X-X-R motif
HgeneARRB1chr11:75062632chr11:82550467ENST00000360025-115385_3956411.0MotifNote=[DE]-X(1%2C2)-F-X-X-[FL]-X-X-X-R motif
HgeneARRB1chr11:75062632chr11:82550467ENST00000420843-116385_3956419.0MotifNote=[DE]-X(1%2C2)-F-X-X-[FL]-X-X-X-R motif
TgenePRCPchr11:75062632chr11:82549616ENST0000031301069194_334362497.0RegionNote=SKS domain
TgenePRCPchr11:75062632chr11:82549616ENST00000393399710194_334383518.0RegionNote=SKS domain
TgenePRCPchr11:75062632chr11:82550467ENST0000031301059194_334307497.0RegionNote=SKS domain
TgenePRCPchr11:75062632chr11:82550467ENST00000393399610194_334328518.0RegionNote=SKS domain


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Fusion Gene Sequence for ARRB1-PRCP


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>6845_6845_1_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000360025_PRCP_chr11_82549616_ENST00000313010_length(transcript)=1927nt_BP=118nt
GGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCCTGGGCGCTGACGCCGCGGACCTCCCTGCGACCGT
CGCGGACCATGGGCGACAAAGGGACCCGGCCTGCACAGAAGTAGTCATGCCCTTTTGTACTAATGGTGTCGATGACATGTTTGAACCTCA
CTCATGGAACTTAAAGGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGACCAAGGCCCTCCTGGATCACTACTATGTATGGAGG
CAAAAACATTAGTTCACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCTGGTCAGGAGGTGGAGTAACTAAGGATATCACAGA
CACTCTGGTTGCAGTCACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCAAGAATGCCTTGGATCCTATGTCTGTGCTGTTAGC
CCGCTCCTTGGAAGTTAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTGCGGGAAAGCAGCACTGAGAAACTTTTGATTGTTT
TCAATTTCTTCTTTTATGTTCACACCACCACATTCCCATTCACTTTGATTTTCTACATGTAATTACCTTCTTTTGTTTATCATTAGATTT
GATGGGGCCAAAGTTGAGATAGAATAGAGGGTGATGACGGTAAGAGCAAGTGTCCCATGAATGTGATTTCCTGGGTTCTCACTGTCTTTG
CACCACGTCTAGGAAGAATCTTCTTGATAGCTCTCCCACACCATCAGTGGCCCTCATAACTGGAGTAGAGTTCCTGGTTGCTTTTCATAA
GAGGGAGAGTTACTTTCTTTGTATCTCTGCAAGCAGAGATTTCTCTTTGGTTTTGAGGTTGAAGTGTCTTTGGCCCATTTGTAAGTCCCC
ATCCCTACCCTACACAAAGTAAAAGCAGAAGATAGATAAAAAATGATGTAATTGCAGCTGGTAGGATGTCTGGTGCCAATCCAGGAAGTG
AGAGCCATTTCTTTTGTACCGGATTTAATGACTTTGAACTGTGCTGTAAATAAATAATACAGCTGGACCTTATACCTGTGTGTTGCTTCT
GAAGCTCACTTCAACTCCGGCTGATGGAAATGCTGTGTGCACTGGGCTTAGCTGTTTTTGGAAAGTCCTTTAATTTTTTCTCTTCCACTT
GGCAGCTTTTCTTAGTTCTGGGATGTTGGCCACTGTGGTACTGCCAGTAAGAAATCTGGCCTTTTTCTGCTCCATTTCTCTTTGTTTCTA
AGGTCAGTTTTAATTTGTTTGAATTCTGCCAGTTTAGGAAAATGACTCTGTTTTGTCTTTTTAAATCTGAGCAAGCTTTATGCTGTAGTC
ACTAATTATATTTCAGTAAGAAGCCTTTAAAAATTGATGAATCAGCTATTCCAAAAGTAGAATATAGTAATATTCAGCTTTTAAATTTTT
AAAATTTTATTTTCTGATAGTTGTTACTGCTGTCATTAAAACCAGAAGTGTTAGACACTAACAGGCAGGTGCACAAGAACTTTTCTGTAT
GACTTCCAAAAGACAAGCTGACTAATTCATGCAGGCAGCATATTTGACATTAATAAATGGCCAAGCCATTCCTATTTCCAAGGGGTTGGC
TTCTTTCAAGCAGTTCTTACACTGAGACCTTTCTTCAGAGAGCTTTTCTAGGATAACAAATAGGGTTGGATCAAAACCTTTCAGGGACAC
AGAGAGACAGAGAGAGAGAGACTAACAGTTTCTACTCTGTTGAAAGATTTCTTCCTCCTTGTTTCTTTTCATTTTCTCTCAATAATTTTT
TTTTCTTCACCCTGCCTTGGGAACATTTTCTGCTTTTAAAAAACTGTACCTTGAGCTTGATCATTTTTATGGCATTTTTTTTTTTTAAGG

>6845_6845_1_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000360025_PRCP_chr11_82549616_ENST00000313010_length(amino acids)=168AA_BP=34
MARAPPAGWGFSSLGADAADLPATVADHGRQRDPACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISS

--------------------------------------------------------------
>6845_6845_2_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000360025_PRCP_chr11_82549616_ENST00000393399_length(transcript)=1061nt_BP=118nt
GGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCCTGGGCGCTGACGCCGCGGACCTCCCTGCGACCGT
CGCGGACCATGGGCGACAAAGGGACCCGGCCTGCACAGAAGTAGTCATGCCCTTTTGTACTAATGGTGTCGATGACATGTTTGAACCTCA
CTCATGGAACTTAAAGGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGACCAAGGCCCTCCTGGATCACTACTATGTATGGAGG
CAAAAACATTAGTTCACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCTGGTCAGGAGGTGGAGTAACTAAGGATATCACAGA
CACTCTGGTTGCAGTCACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCAAGAATGCCTTGGATCCTATGTCTGTGCTGTTAGC
CCGCTCCTTGGAAGTTAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTGCGGGAAAGCAGCACTGAGAAACTTTTGATTGTTT
TCAATTTCTTCTTTTATGTTCACACCACCACATTCCCATTCACTTTGATTTTCTACATGTAATTACCTTCTTTTGTTTATCATTAGATTT
GATGGGGCCAAAGTTGAGATAGAATAGAGGGTGATGACGGTAAGAGCAAGTGTCCCATGAATGTGATTTCCTGGGTTCTCACTGTCTTTG
CACCACGTCTAGGAAGAATCTTCTTGATAGCTCTCCCACACCATCAGTGGCCCTCATAACTGGAGTAGAGTTCCTGGTTGCTTTTCATAA
GAGGGAGAGTTACTTTCTTTGTATCTCTGCAAGCAGAGATTTCTCTTTGGTTTTGAGGTTGAAGTGTCTTTGGCCCATTTGTAAGTCCCC
ATCCCTACCCTACACAAAGTAAAAGCAGAAGATAGATAAAAAATGATGTAATTGCAGCTGGTAGGATGTCTGGTGCCAATCCAGGAAGTG

>6845_6845_2_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000360025_PRCP_chr11_82549616_ENST00000393399_length(amino acids)=168AA_BP=34
MARAPPAGWGFSSLGADAADLPATVADHGRQRDPACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISS

--------------------------------------------------------------
>6845_6845_3_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000360025_PRCP_chr11_82549616_ENST00000535099_length(transcript)=639nt_BP=118nt
GGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCCTGGGCGCTGACGCCGCGGACCTCCCTGCGACCGT
CGCGGACCATGGGCGACAAAGGGACCCGGCCTGCACAGAAGTAGTCATGCCCTTTTGTACTAATGGTGTCGATGACATGTTTGAACCTCA
CTCATGGAACTTAAAGGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGACCAAGGCCCTCCTGGATCACTACTATGTATGGAGG
CAAAAACATTAGTTCACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCTGGTCAGGAGGTGGAGTAACTAAGGATATCACAGA
CACTCTGGTTGCAGTCACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCAAGAATGCCTTGGATCCTATGTCTGTGCTGTTAGC
CCGCTCCTTGGAAGTTAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTGCGGGAAAGCAGCACTGAGAAACTTTTGATTGTTT
TCAATTTCTTCTTTTATGTTCACACCACCACATTCCCATTCACTTTGATTTTCTACATGTAATTACCTTCTTTTGTTTATCATTAGATTT

>6845_6845_3_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000360025_PRCP_chr11_82549616_ENST00000535099_length(amino acids)=168AA_BP=34
MARAPPAGWGFSSLGADAADLPATVADHGRQRDPACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISS

--------------------------------------------------------------
>6845_6845_4_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000360025_PRCP_chr11_82550467_ENST00000313010_length(transcript)=2092nt_BP=118nt
GGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCCTGGGCGCTGACGCCGCGGACCTCCCTGCGACCGT
CGCGGACCATGGGCGACAAAGGGACCCGGTAGTGTGCCAGTATTTGAAAAATCCCAATGTATCTGATTCACTGCTGCTGCAGAATATTTT
CCAAGCTCTGAATGTATATTACAATTATTCGGGCCAGGTGAAATGCCTGAATATTTCAGAGACAGCAACTAGCAGTCTGGGAACACTGGG
TTGGAGCTATCAGGCCTGCACAGAAGTAGTCATGCCCTTTTGTACTAATGGTGTCGATGACATGTTTGAACCTCACTCATGGAACTTAAA
GGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGACCAAGGCCCTCCTGGATCACTACTATGTATGGAGGCAAAAACATTAGTTC
ACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCTGGTCAGGAGGTGGAGTAACTAAGGATATCACAGACACTCTGGTTGCAGT
CACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCAAGAATGCCTTGGATCCTATGTCTGTGCTGTTAGCCCGCTCCTTGGAAGT
TAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTGCGGGAAAGCAGCACTGAGAAACTTTTGATTGTTTTCAATTTCTTCTTTT
ATGTTCACACCACCACATTCCCATTCACTTTGATTTTCTACATGTAATTACCTTCTTTTGTTTATCATTAGATTTGATGGGGCCAAAGTT
GAGATAGAATAGAGGGTGATGACGGTAAGAGCAAGTGTCCCATGAATGTGATTTCCTGGGTTCTCACTGTCTTTGCACCACGTCTAGGAA
GAATCTTCTTGATAGCTCTCCCACACCATCAGTGGCCCTCATAACTGGAGTAGAGTTCCTGGTTGCTTTTCATAAGAGGGAGAGTTACTT
TCTTTGTATCTCTGCAAGCAGAGATTTCTCTTTGGTTTTGAGGTTGAAGTGTCTTTGGCCCATTTGTAAGTCCCCATCCCTACCCTACAC
AAAGTAAAAGCAGAAGATAGATAAAAAATGATGTAATTGCAGCTGGTAGGATGTCTGGTGCCAATCCAGGAAGTGAGAGCCATTTCTTTT
GTACCGGATTTAATGACTTTGAACTGTGCTGTAAATAAATAATACAGCTGGACCTTATACCTGTGTGTTGCTTCTGAAGCTCACTTCAAC
TCCGGCTGATGGAAATGCTGTGTGCACTGGGCTTAGCTGTTTTTGGAAAGTCCTTTAATTTTTTCTCTTCCACTTGGCAGCTTTTCTTAG
TTCTGGGATGTTGGCCACTGTGGTACTGCCAGTAAGAAATCTGGCCTTTTTCTGCTCCATTTCTCTTTGTTTCTAAGGTCAGTTTTAATT
TGTTTGAATTCTGCCAGTTTAGGAAAATGACTCTGTTTTGTCTTTTTAAATCTGAGCAAGCTTTATGCTGTAGTCACTAATTATATTTCA
GTAAGAAGCCTTTAAAAATTGATGAATCAGCTATTCCAAAAGTAGAATATAGTAATATTCAGCTTTTAAATTTTTAAAATTTTATTTTCT
GATAGTTGTTACTGCTGTCATTAAAACCAGAAGTGTTAGACACTAACAGGCAGGTGCACAAGAACTTTTCTGTATGACTTCCAAAAGACA
AGCTGACTAATTCATGCAGGCAGCATATTTGACATTAATAAATGGCCAAGCCATTCCTATTTCCAAGGGGTTGGCTTCTTTCAAGCAGTT
CTTACACTGAGACCTTTCTTCAGAGAGCTTTTCTAGGATAACAAATAGGGTTGGATCAAAACCTTTCAGGGACACAGAGAGACAGAGAGA
GAGAGACTAACAGTTTCTACTCTGTTGAAAGATTTCTTCCTCCTTGTTTCTTTTCATTTTCTCTCAATAATTTTTTTTTCTTCACCCTGC
CTTGGGAACATTTTCTGCTTTTAAAAAACTGTACCTTGAGCTTGATCATTTTTATGGCATTTTTTTTTTTTAAGGGCATATATAGAGTTC

>6845_6845_4_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000360025_PRCP_chr11_82550467_ENST00000313010_length(amino acids)=223AA_BP=34
MARAPPAGWGFSSLGADAADLPATVADHGRQRDPVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQA
CTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEG

--------------------------------------------------------------
>6845_6845_5_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000360025_PRCP_chr11_82550467_ENST00000393399_length(transcript)=1226nt_BP=118nt
GGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCCTGGGCGCTGACGCCGCGGACCTCCCTGCGACCGT
CGCGGACCATGGGCGACAAAGGGACCCGGTAGTGTGCCAGTATTTGAAAAATCCCAATGTATCTGATTCACTGCTGCTGCAGAATATTTT
CCAAGCTCTGAATGTATATTACAATTATTCGGGCCAGGTGAAATGCCTGAATATTTCAGAGACAGCAACTAGCAGTCTGGGAACACTGGG
TTGGAGCTATCAGGCCTGCACAGAAGTAGTCATGCCCTTTTGTACTAATGGTGTCGATGACATGTTTGAACCTCACTCATGGAACTTAAA
GGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGACCAAGGCCCTCCTGGATCACTACTATGTATGGAGGCAAAAACATTAGTTC
ACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCTGGTCAGGAGGTGGAGTAACTAAGGATATCACAGACACTCTGGTTGCAGT
CACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCAAGAATGCCTTGGATCCTATGTCTGTGCTGTTAGCCCGCTCCTTGGAAGT
TAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTGCGGGAAAGCAGCACTGAGAAACTTTTGATTGTTTTCAATTTCTTCTTTT
ATGTTCACACCACCACATTCCCATTCACTTTGATTTTCTACATGTAATTACCTTCTTTTGTTTATCATTAGATTTGATGGGGCCAAAGTT
GAGATAGAATAGAGGGTGATGACGGTAAGAGCAAGTGTCCCATGAATGTGATTTCCTGGGTTCTCACTGTCTTTGCACCACGTCTAGGAA
GAATCTTCTTGATAGCTCTCCCACACCATCAGTGGCCCTCATAACTGGAGTAGAGTTCCTGGTTGCTTTTCATAAGAGGGAGAGTTACTT
TCTTTGTATCTCTGCAAGCAGAGATTTCTCTTTGGTTTTGAGGTTGAAGTGTCTTTGGCCCATTTGTAAGTCCCCATCCCTACCCTACAC
AAAGTAAAAGCAGAAGATAGATAAAAAATGATGTAATTGCAGCTGGTAGGATGTCTGGTGCCAATCCAGGAAGTGAGAGCCATTTCTTTT

>6845_6845_5_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000360025_PRCP_chr11_82550467_ENST00000393399_length(amino acids)=223AA_BP=34
MARAPPAGWGFSSLGADAADLPATVADHGRQRDPVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQA
CTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEG

--------------------------------------------------------------
>6845_6845_6_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000360025_PRCP_chr11_82550467_ENST00000535099_length(transcript)=804nt_BP=118nt
GGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCCTGGGCGCTGACGCCGCGGACCTCCCTGCGACCGT
CGCGGACCATGGGCGACAAAGGGACCCGGTAGTGTGCCAGTATTTGAAAAATCCCAATGTATCTGATTCACTGCTGCTGCAGAATATTTT
CCAAGCTCTGAATGTATATTACAATTATTCGGGCCAGGTGAAATGCCTGAATATTTCAGAGACAGCAACTAGCAGTCTGGGAACACTGGG
TTGGAGCTATCAGGCCTGCACAGAAGTAGTCATGCCCTTTTGTACTAATGGTGTCGATGACATGTTTGAACCTCACTCATGGAACTTAAA
GGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGACCAAGGCCCTCCTGGATCACTACTATGTATGGAGGCAAAAACATTAGTTC
ACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCTGGTCAGGAGGTGGAGTAACTAAGGATATCACAGACACTCTGGTTGCAGT
CACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCAAGAATGCCTTGGATCCTATGTCTGTGCTGTTAGCCCGCTCCTTGGAAGT
TAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTGCGGGAAAGCAGCACTGAGAAACTTTTGATTGTTTTCAATTTCTTCTTTT

>6845_6845_6_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000360025_PRCP_chr11_82550467_ENST00000535099_length(amino acids)=223AA_BP=34
MARAPPAGWGFSSLGADAADLPATVADHGRQRDPVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQA
CTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEG

--------------------------------------------------------------
>6845_6845_7_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000393505_PRCP_chr11_82549616_ENST00000313010_length(transcript)=2051nt_BP=242nt
ACCCCGCGCGGTTCCACGCCCCTGGCCGCGGCCCGGGCGCTGCGCTGCTCGACGCGGCGGGCGGCGGGCGGGGACCGGGGGCGGGGGCGG
CGGCGGCGGCCGGGAGAGCGGAGGAGGCGGAGCAGGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCC
TGGGCGCTGACGCCGCGGACCTCCCTGCGACCGTCGCGGACCATGGGCGACAAAGGGACCCGGCCTGCACAGAAGTAGTCATGCCCTTTT
GTACTAATGGTGTCGATGACATGTTTGAACCTCACTCATGGAACTTAAAGGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGAC
CAAGGCCCTCCTGGATCACTACTATGTATGGAGGCAAAAACATTAGTTCACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCT
GGTCAGGAGGTGGAGTAACTAAGGATATCACAGACACTCTGGTTGCAGTCACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCA
AGAATGCCTTGGATCCTATGTCTGTGCTGTTAGCCCGCTCCTTGGAAGTTAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTG
CGGGAAAGCAGCACTGAGAAACTTTTGATTGTTTTCAATTTCTTCTTTTATGTTCACACCACCACATTCCCATTCACTTTGATTTTCTAC
ATGTAATTACCTTCTTTTGTTTATCATTAGATTTGATGGGGCCAAAGTTGAGATAGAATAGAGGGTGATGACGGTAAGAGCAAGTGTCCC
ATGAATGTGATTTCCTGGGTTCTCACTGTCTTTGCACCACGTCTAGGAAGAATCTTCTTGATAGCTCTCCCACACCATCAGTGGCCCTCA
TAACTGGAGTAGAGTTCCTGGTTGCTTTTCATAAGAGGGAGAGTTACTTTCTTTGTATCTCTGCAAGCAGAGATTTCTCTTTGGTTTTGA
GGTTGAAGTGTCTTTGGCCCATTTGTAAGTCCCCATCCCTACCCTACACAAAGTAAAAGCAGAAGATAGATAAAAAATGATGTAATTGCA
GCTGGTAGGATGTCTGGTGCCAATCCAGGAAGTGAGAGCCATTTCTTTTGTACCGGATTTAATGACTTTGAACTGTGCTGTAAATAAATA
ATACAGCTGGACCTTATACCTGTGTGTTGCTTCTGAAGCTCACTTCAACTCCGGCTGATGGAAATGCTGTGTGCACTGGGCTTAGCTGTT
TTTGGAAAGTCCTTTAATTTTTTCTCTTCCACTTGGCAGCTTTTCTTAGTTCTGGGATGTTGGCCACTGTGGTACTGCCAGTAAGAAATC
TGGCCTTTTTCTGCTCCATTTCTCTTTGTTTCTAAGGTCAGTTTTAATTTGTTTGAATTCTGCCAGTTTAGGAAAATGACTCTGTTTTGT
CTTTTTAAATCTGAGCAAGCTTTATGCTGTAGTCACTAATTATATTTCAGTAAGAAGCCTTTAAAAATTGATGAATCAGCTATTCCAAAA
GTAGAATATAGTAATATTCAGCTTTTAAATTTTTAAAATTTTATTTTCTGATAGTTGTTACTGCTGTCATTAAAACCAGAAGTGTTAGAC
ACTAACAGGCAGGTGCACAAGAACTTTTCTGTATGACTTCCAAAAGACAAGCTGACTAATTCATGCAGGCAGCATATTTGACATTAATAA
ATGGCCAAGCCATTCCTATTTCCAAGGGGTTGGCTTCTTTCAAGCAGTTCTTACACTGAGACCTTTCTTCAGAGAGCTTTTCTAGGATAA
CAAATAGGGTTGGATCAAAACCTTTCAGGGACACAGAGAGACAGAGAGAGAGAGACTAACAGTTTCTACTCTGTTGAAAGATTTCTTCCT
CCTTGTTTCTTTTCATTTTCTCTCAATAATTTTTTTTTCTTCACCCTGCCTTGGGAACATTTTCTGCTTTTAAAAAACTGTACCTTGAGC

>6845_6845_7_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000393505_PRCP_chr11_82549616_ENST00000313010_length(amino acids)=200AA_BP=66
MLDAAGGGRGPGAGAAAAAGRAEEAEQGAGSGLARAPPAGWGFSSLGADAADLPATVADHGRQRDPACTEVVMPFCTNGVDDMFEPHSWN
LKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSL

--------------------------------------------------------------
>6845_6845_8_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000393505_PRCP_chr11_82549616_ENST00000393399_length(transcript)=1185nt_BP=242nt
ACCCCGCGCGGTTCCACGCCCCTGGCCGCGGCCCGGGCGCTGCGCTGCTCGACGCGGCGGGCGGCGGGCGGGGACCGGGGGCGGGGGCGG
CGGCGGCGGCCGGGAGAGCGGAGGAGGCGGAGCAGGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCC
TGGGCGCTGACGCCGCGGACCTCCCTGCGACCGTCGCGGACCATGGGCGACAAAGGGACCCGGCCTGCACAGAAGTAGTCATGCCCTTTT
GTACTAATGGTGTCGATGACATGTTTGAACCTCACTCATGGAACTTAAAGGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGAC
CAAGGCCCTCCTGGATCACTACTATGTATGGAGGCAAAAACATTAGTTCACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCT
GGTCAGGAGGTGGAGTAACTAAGGATATCACAGACACTCTGGTTGCAGTCACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCA
AGAATGCCTTGGATCCTATGTCTGTGCTGTTAGCCCGCTCCTTGGAAGTTAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTG
CGGGAAAGCAGCACTGAGAAACTTTTGATTGTTTTCAATTTCTTCTTTTATGTTCACACCACCACATTCCCATTCACTTTGATTTTCTAC
ATGTAATTACCTTCTTTTGTTTATCATTAGATTTGATGGGGCCAAAGTTGAGATAGAATAGAGGGTGATGACGGTAAGAGCAAGTGTCCC
ATGAATGTGATTTCCTGGGTTCTCACTGTCTTTGCACCACGTCTAGGAAGAATCTTCTTGATAGCTCTCCCACACCATCAGTGGCCCTCA
TAACTGGAGTAGAGTTCCTGGTTGCTTTTCATAAGAGGGAGAGTTACTTTCTTTGTATCTCTGCAAGCAGAGATTTCTCTTTGGTTTTGA
GGTTGAAGTGTCTTTGGCCCATTTGTAAGTCCCCATCCCTACCCTACACAAAGTAAAAGCAGAAGATAGATAAAAAATGATGTAATTGCA
GCTGGTAGGATGTCTGGTGCCAATCCAGGAAGTGAGAGCCATTTCTTTTGTACCGGATTTAATGACTTTGAACTGTGCTGTAAATAAATA

>6845_6845_8_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000393505_PRCP_chr11_82549616_ENST00000393399_length(amino acids)=200AA_BP=66
MLDAAGGGRGPGAGAAAAAGRAEEAEQGAGSGLARAPPAGWGFSSLGADAADLPATVADHGRQRDPACTEVVMPFCTNGVDDMFEPHSWN
LKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSL

--------------------------------------------------------------
>6845_6845_9_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000393505_PRCP_chr11_82549616_ENST00000535099_length(transcript)=763nt_BP=242nt
ACCCCGCGCGGTTCCACGCCCCTGGCCGCGGCCCGGGCGCTGCGCTGCTCGACGCGGCGGGCGGCGGGCGGGGACCGGGGGCGGGGGCGG
CGGCGGCGGCCGGGAGAGCGGAGGAGGCGGAGCAGGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCC
TGGGCGCTGACGCCGCGGACCTCCCTGCGACCGTCGCGGACCATGGGCGACAAAGGGACCCGGCCTGCACAGAAGTAGTCATGCCCTTTT
GTACTAATGGTGTCGATGACATGTTTGAACCTCACTCATGGAACTTAAAGGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGAC
CAAGGCCCTCCTGGATCACTACTATGTATGGAGGCAAAAACATTAGTTCACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCT
GGTCAGGAGGTGGAGTAACTAAGGATATCACAGACACTCTGGTTGCAGTCACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCA
AGAATGCCTTGGATCCTATGTCTGTGCTGTTAGCCCGCTCCTTGGAAGTTAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTG
CGGGAAAGCAGCACTGAGAAACTTTTGATTGTTTTCAATTTCTTCTTTTATGTTCACACCACCACATTCCCATTCACTTTGATTTTCTAC

>6845_6845_9_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000393505_PRCP_chr11_82549616_ENST00000535099_length(amino acids)=200AA_BP=66
MLDAAGGGRGPGAGAAAAAGRAEEAEQGAGSGLARAPPAGWGFSSLGADAADLPATVADHGRQRDPACTEVVMPFCTNGVDDMFEPHSWN
LKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSL

--------------------------------------------------------------
>6845_6845_10_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000393505_PRCP_chr11_82550467_ENST00000313010_length(transcript)=2216nt_BP=242nt
ACCCCGCGCGGTTCCACGCCCCTGGCCGCGGCCCGGGCGCTGCGCTGCTCGACGCGGCGGGCGGCGGGCGGGGACCGGGGGCGGGGGCGG
CGGCGGCGGCCGGGAGAGCGGAGGAGGCGGAGCAGGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCC
TGGGCGCTGACGCCGCGGACCTCCCTGCGACCGTCGCGGACCATGGGCGACAAAGGGACCCGGTAGTGTGCCAGTATTTGAAAAATCCCA
ATGTATCTGATTCACTGCTGCTGCAGAATATTTTCCAAGCTCTGAATGTATATTACAATTATTCGGGCCAGGTGAAATGCCTGAATATTT
CAGAGACAGCAACTAGCAGTCTGGGAACACTGGGTTGGAGCTATCAGGCCTGCACAGAAGTAGTCATGCCCTTTTGTACTAATGGTGTCG
ATGACATGTTTGAACCTCACTCATGGAACTTAAAGGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGACCAAGGCCCTCCTGGA
TCACTACTATGTATGGAGGCAAAAACATTAGTTCACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCTGGTCAGGAGGTGGAG
TAACTAAGGATATCACAGACACTCTGGTTGCAGTCACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCAAGAATGCCTTGGATC
CTATGTCTGTGCTGTTAGCCCGCTCCTTGGAAGTTAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTGCGGGAAAGCAGCACT
GAGAAACTTTTGATTGTTTTCAATTTCTTCTTTTATGTTCACACCACCACATTCCCATTCACTTTGATTTTCTACATGTAATTACCTTCT
TTTGTTTATCATTAGATTTGATGGGGCCAAAGTTGAGATAGAATAGAGGGTGATGACGGTAAGAGCAAGTGTCCCATGAATGTGATTTCC
TGGGTTCTCACTGTCTTTGCACCACGTCTAGGAAGAATCTTCTTGATAGCTCTCCCACACCATCAGTGGCCCTCATAACTGGAGTAGAGT
TCCTGGTTGCTTTTCATAAGAGGGAGAGTTACTTTCTTTGTATCTCTGCAAGCAGAGATTTCTCTTTGGTTTTGAGGTTGAAGTGTCTTT
GGCCCATTTGTAAGTCCCCATCCCTACCCTACACAAAGTAAAAGCAGAAGATAGATAAAAAATGATGTAATTGCAGCTGGTAGGATGTCT
GGTGCCAATCCAGGAAGTGAGAGCCATTTCTTTTGTACCGGATTTAATGACTTTGAACTGTGCTGTAAATAAATAATACAGCTGGACCTT
ATACCTGTGTGTTGCTTCTGAAGCTCACTTCAACTCCGGCTGATGGAAATGCTGTGTGCACTGGGCTTAGCTGTTTTTGGAAAGTCCTTT
AATTTTTTCTCTTCCACTTGGCAGCTTTTCTTAGTTCTGGGATGTTGGCCACTGTGGTACTGCCAGTAAGAAATCTGGCCTTTTTCTGCT
CCATTTCTCTTTGTTTCTAAGGTCAGTTTTAATTTGTTTGAATTCTGCCAGTTTAGGAAAATGACTCTGTTTTGTCTTTTTAAATCTGAG
CAAGCTTTATGCTGTAGTCACTAATTATATTTCAGTAAGAAGCCTTTAAAAATTGATGAATCAGCTATTCCAAAAGTAGAATATAGTAAT
ATTCAGCTTTTAAATTTTTAAAATTTTATTTTCTGATAGTTGTTACTGCTGTCATTAAAACCAGAAGTGTTAGACACTAACAGGCAGGTG
CACAAGAACTTTTCTGTATGACTTCCAAAAGACAAGCTGACTAATTCATGCAGGCAGCATATTTGACATTAATAAATGGCCAAGCCATTC
CTATTTCCAAGGGGTTGGCTTCTTTCAAGCAGTTCTTACACTGAGACCTTTCTTCAGAGAGCTTTTCTAGGATAACAAATAGGGTTGGAT
CAAAACCTTTCAGGGACACAGAGAGACAGAGAGAGAGAGACTAACAGTTTCTACTCTGTTGAAAGATTTCTTCCTCCTTGTTTCTTTTCA
TTTTCTCTCAATAATTTTTTTTTCTTCACCCTGCCTTGGGAACATTTTCTGCTTTTAAAAAACTGTACCTTGAGCTTGATCATTTTTATG

>6845_6845_10_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000393505_PRCP_chr11_82550467_ENST00000313010_length(amino acids)=255AA_BP=66
MLDAAGGGRGPGAGAAAAAGRAEEAEQGAGSGLARAPPAGWGFSSLGADAADLPATVADHGRQRDPVVCQYLKNPNVSDSLLLQNIFQAL
NVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTN

--------------------------------------------------------------
>6845_6845_11_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000393505_PRCP_chr11_82550467_ENST00000393399_length(transcript)=1350nt_BP=242nt
ACCCCGCGCGGTTCCACGCCCCTGGCCGCGGCCCGGGCGCTGCGCTGCTCGACGCGGCGGGCGGCGGGCGGGGACCGGGGGCGGGGGCGG
CGGCGGCGGCCGGGAGAGCGGAGGAGGCGGAGCAGGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCC
TGGGCGCTGACGCCGCGGACCTCCCTGCGACCGTCGCGGACCATGGGCGACAAAGGGACCCGGTAGTGTGCCAGTATTTGAAAAATCCCA
ATGTATCTGATTCACTGCTGCTGCAGAATATTTTCCAAGCTCTGAATGTATATTACAATTATTCGGGCCAGGTGAAATGCCTGAATATTT
CAGAGACAGCAACTAGCAGTCTGGGAACACTGGGTTGGAGCTATCAGGCCTGCACAGAAGTAGTCATGCCCTTTTGTACTAATGGTGTCG
ATGACATGTTTGAACCTCACTCATGGAACTTAAAGGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGACCAAGGCCCTCCTGGA
TCACTACTATGTATGGAGGCAAAAACATTAGTTCACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCTGGTCAGGAGGTGGAG
TAACTAAGGATATCACAGACACTCTGGTTGCAGTCACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCAAGAATGCCTTGGATC
CTATGTCTGTGCTGTTAGCCCGCTCCTTGGAAGTTAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTGCGGGAAAGCAGCACT
GAGAAACTTTTGATTGTTTTCAATTTCTTCTTTTATGTTCACACCACCACATTCCCATTCACTTTGATTTTCTACATGTAATTACCTTCT
TTTGTTTATCATTAGATTTGATGGGGCCAAAGTTGAGATAGAATAGAGGGTGATGACGGTAAGAGCAAGTGTCCCATGAATGTGATTTCC
TGGGTTCTCACTGTCTTTGCACCACGTCTAGGAAGAATCTTCTTGATAGCTCTCCCACACCATCAGTGGCCCTCATAACTGGAGTAGAGT
TCCTGGTTGCTTTTCATAAGAGGGAGAGTTACTTTCTTTGTATCTCTGCAAGCAGAGATTTCTCTTTGGTTTTGAGGTTGAAGTGTCTTT
GGCCCATTTGTAAGTCCCCATCCCTACCCTACACAAAGTAAAAGCAGAAGATAGATAAAAAATGATGTAATTGCAGCTGGTAGGATGTCT
GGTGCCAATCCAGGAAGTGAGAGCCATTTCTTTTGTACCGGATTTAATGACTTTGAACTGTGCTGTAAATAAATAATACAGCTGGACCTT

>6845_6845_11_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000393505_PRCP_chr11_82550467_ENST00000393399_length(amino acids)=255AA_BP=66
MLDAAGGGRGPGAGAAAAAGRAEEAEQGAGSGLARAPPAGWGFSSLGADAADLPATVADHGRQRDPVVCQYLKNPNVSDSLLLQNIFQAL
NVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTN

--------------------------------------------------------------
>6845_6845_12_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000393505_PRCP_chr11_82550467_ENST00000535099_length(transcript)=928nt_BP=242nt
ACCCCGCGCGGTTCCACGCCCCTGGCCGCGGCCCGGGCGCTGCGCTGCTCGACGCGGCGGGCGGCGGGCGGGGACCGGGGGCGGGGGCGG
CGGCGGCGGCCGGGAGAGCGGAGGAGGCGGAGCAGGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCC
TGGGCGCTGACGCCGCGGACCTCCCTGCGACCGTCGCGGACCATGGGCGACAAAGGGACCCGGTAGTGTGCCAGTATTTGAAAAATCCCA
ATGTATCTGATTCACTGCTGCTGCAGAATATTTTCCAAGCTCTGAATGTATATTACAATTATTCGGGCCAGGTGAAATGCCTGAATATTT
CAGAGACAGCAACTAGCAGTCTGGGAACACTGGGTTGGAGCTATCAGGCCTGCACAGAAGTAGTCATGCCCTTTTGTACTAATGGTGTCG
ATGACATGTTTGAACCTCACTCATGGAACTTAAAGGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGACCAAGGCCCTCCTGGA
TCACTACTATGTATGGAGGCAAAAACATTAGTTCACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCTGGTCAGGAGGTGGAG
TAACTAAGGATATCACAGACACTCTGGTTGCAGTCACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCAAGAATGCCTTGGATC
CTATGTCTGTGCTGTTAGCCCGCTCCTTGGAAGTTAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTGCGGGAAAGCAGCACT
GAGAAACTTTTGATTGTTTTCAATTTCTTCTTTTATGTTCACACCACCACATTCCCATTCACTTTGATTTTCTACATGTAATTACCTTCT

>6845_6845_12_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000393505_PRCP_chr11_82550467_ENST00000535099_length(amino acids)=255AA_BP=66
MLDAAGGGRGPGAGAAAAAGRAEEAEQGAGSGLARAPPAGWGFSSLGADAADLPATVADHGRQRDPVVCQYLKNPNVSDSLLLQNIFQAL
NVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTN

--------------------------------------------------------------
>6845_6845_13_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000420843_PRCP_chr11_82549616_ENST00000313010_length(transcript)=1927nt_BP=118nt
GGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCCTGGGCGCTGACGCCGCGGACCTCCCTGCGACCGT
CGCGGACCATGGGCGACAAAGGGACCCGGCCTGCACAGAAGTAGTCATGCCCTTTTGTACTAATGGTGTCGATGACATGTTTGAACCTCA
CTCATGGAACTTAAAGGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGACCAAGGCCCTCCTGGATCACTACTATGTATGGAGG
CAAAAACATTAGTTCACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCTGGTCAGGAGGTGGAGTAACTAAGGATATCACAGA
CACTCTGGTTGCAGTCACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCAAGAATGCCTTGGATCCTATGTCTGTGCTGTTAGC
CCGCTCCTTGGAAGTTAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTGCGGGAAAGCAGCACTGAGAAACTTTTGATTGTTT
TCAATTTCTTCTTTTATGTTCACACCACCACATTCCCATTCACTTTGATTTTCTACATGTAATTACCTTCTTTTGTTTATCATTAGATTT
GATGGGGCCAAAGTTGAGATAGAATAGAGGGTGATGACGGTAAGAGCAAGTGTCCCATGAATGTGATTTCCTGGGTTCTCACTGTCTTTG
CACCACGTCTAGGAAGAATCTTCTTGATAGCTCTCCCACACCATCAGTGGCCCTCATAACTGGAGTAGAGTTCCTGGTTGCTTTTCATAA
GAGGGAGAGTTACTTTCTTTGTATCTCTGCAAGCAGAGATTTCTCTTTGGTTTTGAGGTTGAAGTGTCTTTGGCCCATTTGTAAGTCCCC
ATCCCTACCCTACACAAAGTAAAAGCAGAAGATAGATAAAAAATGATGTAATTGCAGCTGGTAGGATGTCTGGTGCCAATCCAGGAAGTG
AGAGCCATTTCTTTTGTACCGGATTTAATGACTTTGAACTGTGCTGTAAATAAATAATACAGCTGGACCTTATACCTGTGTGTTGCTTCT
GAAGCTCACTTCAACTCCGGCTGATGGAAATGCTGTGTGCACTGGGCTTAGCTGTTTTTGGAAAGTCCTTTAATTTTTTCTCTTCCACTT
GGCAGCTTTTCTTAGTTCTGGGATGTTGGCCACTGTGGTACTGCCAGTAAGAAATCTGGCCTTTTTCTGCTCCATTTCTCTTTGTTTCTA
AGGTCAGTTTTAATTTGTTTGAATTCTGCCAGTTTAGGAAAATGACTCTGTTTTGTCTTTTTAAATCTGAGCAAGCTTTATGCTGTAGTC
ACTAATTATATTTCAGTAAGAAGCCTTTAAAAATTGATGAATCAGCTATTCCAAAAGTAGAATATAGTAATATTCAGCTTTTAAATTTTT
AAAATTTTATTTTCTGATAGTTGTTACTGCTGTCATTAAAACCAGAAGTGTTAGACACTAACAGGCAGGTGCACAAGAACTTTTCTGTAT
GACTTCCAAAAGACAAGCTGACTAATTCATGCAGGCAGCATATTTGACATTAATAAATGGCCAAGCCATTCCTATTTCCAAGGGGTTGGC
TTCTTTCAAGCAGTTCTTACACTGAGACCTTTCTTCAGAGAGCTTTTCTAGGATAACAAATAGGGTTGGATCAAAACCTTTCAGGGACAC
AGAGAGACAGAGAGAGAGAGACTAACAGTTTCTACTCTGTTGAAAGATTTCTTCCTCCTTGTTTCTTTTCATTTTCTCTCAATAATTTTT
TTTTCTTCACCCTGCCTTGGGAACATTTTCTGCTTTTAAAAAACTGTACCTTGAGCTTGATCATTTTTATGGCATTTTTTTTTTTTAAGG

>6845_6845_13_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000420843_PRCP_chr11_82549616_ENST00000313010_length(amino acids)=168AA_BP=34
MARAPPAGWGFSSLGADAADLPATVADHGRQRDPACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISS

--------------------------------------------------------------
>6845_6845_14_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000420843_PRCP_chr11_82549616_ENST00000393399_length(transcript)=1061nt_BP=118nt
GGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCCTGGGCGCTGACGCCGCGGACCTCCCTGCGACCGT
CGCGGACCATGGGCGACAAAGGGACCCGGCCTGCACAGAAGTAGTCATGCCCTTTTGTACTAATGGTGTCGATGACATGTTTGAACCTCA
CTCATGGAACTTAAAGGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGACCAAGGCCCTCCTGGATCACTACTATGTATGGAGG
CAAAAACATTAGTTCACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCTGGTCAGGAGGTGGAGTAACTAAGGATATCACAGA
CACTCTGGTTGCAGTCACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCAAGAATGCCTTGGATCCTATGTCTGTGCTGTTAGC
CCGCTCCTTGGAAGTTAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTGCGGGAAAGCAGCACTGAGAAACTTTTGATTGTTT
TCAATTTCTTCTTTTATGTTCACACCACCACATTCCCATTCACTTTGATTTTCTACATGTAATTACCTTCTTTTGTTTATCATTAGATTT
GATGGGGCCAAAGTTGAGATAGAATAGAGGGTGATGACGGTAAGAGCAAGTGTCCCATGAATGTGATTTCCTGGGTTCTCACTGTCTTTG
CACCACGTCTAGGAAGAATCTTCTTGATAGCTCTCCCACACCATCAGTGGCCCTCATAACTGGAGTAGAGTTCCTGGTTGCTTTTCATAA
GAGGGAGAGTTACTTTCTTTGTATCTCTGCAAGCAGAGATTTCTCTTTGGTTTTGAGGTTGAAGTGTCTTTGGCCCATTTGTAAGTCCCC
ATCCCTACCCTACACAAAGTAAAAGCAGAAGATAGATAAAAAATGATGTAATTGCAGCTGGTAGGATGTCTGGTGCCAATCCAGGAAGTG

>6845_6845_14_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000420843_PRCP_chr11_82549616_ENST00000393399_length(amino acids)=168AA_BP=34
MARAPPAGWGFSSLGADAADLPATVADHGRQRDPACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISS

--------------------------------------------------------------
>6845_6845_15_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000420843_PRCP_chr11_82549616_ENST00000535099_length(transcript)=639nt_BP=118nt
GGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCCTGGGCGCTGACGCCGCGGACCTCCCTGCGACCGT
CGCGGACCATGGGCGACAAAGGGACCCGGCCTGCACAGAAGTAGTCATGCCCTTTTGTACTAATGGTGTCGATGACATGTTTGAACCTCA
CTCATGGAACTTAAAGGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGACCAAGGCCCTCCTGGATCACTACTATGTATGGAGG
CAAAAACATTAGTTCACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCTGGTCAGGAGGTGGAGTAACTAAGGATATCACAGA
CACTCTGGTTGCAGTCACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCAAGAATGCCTTGGATCCTATGTCTGTGCTGTTAGC
CCGCTCCTTGGAAGTTAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTGCGGGAAAGCAGCACTGAGAAACTTTTGATTGTTT
TCAATTTCTTCTTTTATGTTCACACCACCACATTCCCATTCACTTTGATTTTCTACATGTAATTACCTTCTTTTGTTTATCATTAGATTT

>6845_6845_15_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000420843_PRCP_chr11_82549616_ENST00000535099_length(amino acids)=168AA_BP=34
MARAPPAGWGFSSLGADAADLPATVADHGRQRDPACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISS

--------------------------------------------------------------
>6845_6845_16_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000420843_PRCP_chr11_82550467_ENST00000313010_length(transcript)=2092nt_BP=118nt
GGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCCTGGGCGCTGACGCCGCGGACCTCCCTGCGACCGT
CGCGGACCATGGGCGACAAAGGGACCCGGTAGTGTGCCAGTATTTGAAAAATCCCAATGTATCTGATTCACTGCTGCTGCAGAATATTTT
CCAAGCTCTGAATGTATATTACAATTATTCGGGCCAGGTGAAATGCCTGAATATTTCAGAGACAGCAACTAGCAGTCTGGGAACACTGGG
TTGGAGCTATCAGGCCTGCACAGAAGTAGTCATGCCCTTTTGTACTAATGGTGTCGATGACATGTTTGAACCTCACTCATGGAACTTAAA
GGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGACCAAGGCCCTCCTGGATCACTACTATGTATGGAGGCAAAAACATTAGTTC
ACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCTGGTCAGGAGGTGGAGTAACTAAGGATATCACAGACACTCTGGTTGCAGT
CACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCAAGAATGCCTTGGATCCTATGTCTGTGCTGTTAGCCCGCTCCTTGGAAGT
TAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTGCGGGAAAGCAGCACTGAGAAACTTTTGATTGTTTTCAATTTCTTCTTTT
ATGTTCACACCACCACATTCCCATTCACTTTGATTTTCTACATGTAATTACCTTCTTTTGTTTATCATTAGATTTGATGGGGCCAAAGTT
GAGATAGAATAGAGGGTGATGACGGTAAGAGCAAGTGTCCCATGAATGTGATTTCCTGGGTTCTCACTGTCTTTGCACCACGTCTAGGAA
GAATCTTCTTGATAGCTCTCCCACACCATCAGTGGCCCTCATAACTGGAGTAGAGTTCCTGGTTGCTTTTCATAAGAGGGAGAGTTACTT
TCTTTGTATCTCTGCAAGCAGAGATTTCTCTTTGGTTTTGAGGTTGAAGTGTCTTTGGCCCATTTGTAAGTCCCCATCCCTACCCTACAC
AAAGTAAAAGCAGAAGATAGATAAAAAATGATGTAATTGCAGCTGGTAGGATGTCTGGTGCCAATCCAGGAAGTGAGAGCCATTTCTTTT
GTACCGGATTTAATGACTTTGAACTGTGCTGTAAATAAATAATACAGCTGGACCTTATACCTGTGTGTTGCTTCTGAAGCTCACTTCAAC
TCCGGCTGATGGAAATGCTGTGTGCACTGGGCTTAGCTGTTTTTGGAAAGTCCTTTAATTTTTTCTCTTCCACTTGGCAGCTTTTCTTAG
TTCTGGGATGTTGGCCACTGTGGTACTGCCAGTAAGAAATCTGGCCTTTTTCTGCTCCATTTCTCTTTGTTTCTAAGGTCAGTTTTAATT
TGTTTGAATTCTGCCAGTTTAGGAAAATGACTCTGTTTTGTCTTTTTAAATCTGAGCAAGCTTTATGCTGTAGTCACTAATTATATTTCA
GTAAGAAGCCTTTAAAAATTGATGAATCAGCTATTCCAAAAGTAGAATATAGTAATATTCAGCTTTTAAATTTTTAAAATTTTATTTTCT
GATAGTTGTTACTGCTGTCATTAAAACCAGAAGTGTTAGACACTAACAGGCAGGTGCACAAGAACTTTTCTGTATGACTTCCAAAAGACA
AGCTGACTAATTCATGCAGGCAGCATATTTGACATTAATAAATGGCCAAGCCATTCCTATTTCCAAGGGGTTGGCTTCTTTCAAGCAGTT
CTTACACTGAGACCTTTCTTCAGAGAGCTTTTCTAGGATAACAAATAGGGTTGGATCAAAACCTTTCAGGGACACAGAGAGACAGAGAGA
GAGAGACTAACAGTTTCTACTCTGTTGAAAGATTTCTTCCTCCTTGTTTCTTTTCATTTTCTCTCAATAATTTTTTTTTCTTCACCCTGC
CTTGGGAACATTTTCTGCTTTTAAAAAACTGTACCTTGAGCTTGATCATTTTTATGGCATTTTTTTTTTTTAAGGGCATATATAGAGTTC

>6845_6845_16_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000420843_PRCP_chr11_82550467_ENST00000313010_length(amino acids)=223AA_BP=34
MARAPPAGWGFSSLGADAADLPATVADHGRQRDPVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQA
CTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEG

--------------------------------------------------------------
>6845_6845_17_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000420843_PRCP_chr11_82550467_ENST00000393399_length(transcript)=1226nt_BP=118nt
GGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCCTGGGCGCTGACGCCGCGGACCTCCCTGCGACCGT
CGCGGACCATGGGCGACAAAGGGACCCGGTAGTGTGCCAGTATTTGAAAAATCCCAATGTATCTGATTCACTGCTGCTGCAGAATATTTT
CCAAGCTCTGAATGTATATTACAATTATTCGGGCCAGGTGAAATGCCTGAATATTTCAGAGACAGCAACTAGCAGTCTGGGAACACTGGG
TTGGAGCTATCAGGCCTGCACAGAAGTAGTCATGCCCTTTTGTACTAATGGTGTCGATGACATGTTTGAACCTCACTCATGGAACTTAAA
GGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGACCAAGGCCCTCCTGGATCACTACTATGTATGGAGGCAAAAACATTAGTTC
ACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCTGGTCAGGAGGTGGAGTAACTAAGGATATCACAGACACTCTGGTTGCAGT
CACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCAAGAATGCCTTGGATCCTATGTCTGTGCTGTTAGCCCGCTCCTTGGAAGT
TAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTGCGGGAAAGCAGCACTGAGAAACTTTTGATTGTTTTCAATTTCTTCTTTT
ATGTTCACACCACCACATTCCCATTCACTTTGATTTTCTACATGTAATTACCTTCTTTTGTTTATCATTAGATTTGATGGGGCCAAAGTT
GAGATAGAATAGAGGGTGATGACGGTAAGAGCAAGTGTCCCATGAATGTGATTTCCTGGGTTCTCACTGTCTTTGCACCACGTCTAGGAA
GAATCTTCTTGATAGCTCTCCCACACCATCAGTGGCCCTCATAACTGGAGTAGAGTTCCTGGTTGCTTTTCATAAGAGGGAGAGTTACTT
TCTTTGTATCTCTGCAAGCAGAGATTTCTCTTTGGTTTTGAGGTTGAAGTGTCTTTGGCCCATTTGTAAGTCCCCATCCCTACCCTACAC
AAAGTAAAAGCAGAAGATAGATAAAAAATGATGTAATTGCAGCTGGTAGGATGTCTGGTGCCAATCCAGGAAGTGAGAGCCATTTCTTTT

>6845_6845_17_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000420843_PRCP_chr11_82550467_ENST00000393399_length(amino acids)=223AA_BP=34
MARAPPAGWGFSSLGADAADLPATVADHGRQRDPVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQA
CTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEG

--------------------------------------------------------------
>6845_6845_18_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000420843_PRCP_chr11_82550467_ENST00000535099_length(transcript)=804nt_BP=118nt
GGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAGCCTGGGCGCTGACGCCGCGGACCTCCCTGCGACCGT
CGCGGACCATGGGCGACAAAGGGACCCGGTAGTGTGCCAGTATTTGAAAAATCCCAATGTATCTGATTCACTGCTGCTGCAGAATATTTT
CCAAGCTCTGAATGTATATTACAATTATTCGGGCCAGGTGAAATGCCTGAATATTTCAGAGACAGCAACTAGCAGTCTGGGAACACTGGG
TTGGAGCTATCAGGCCTGCACAGAAGTAGTCATGCCCTTTTGTACTAATGGTGTCGATGACATGTTTGAACCTCACTCATGGAACTTAAA
GGAACTTTCTGATGACTGTTTTCAACAGTGGGGTGTGAGACCAAGGCCCTCCTGGATCACTACTATGTATGGAGGCAAAAACATTAGTTC
ACACACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCTGGTCAGGAGGTGGAGTAACTAAGGATATCACAGACACTCTGGTTGCAGT
CACCATCTCAGAGGGGGCCCACCACTTAGATCTCCGCACCAAGAATGCCTTGGATCCTATGTCTGTGCTGTTAGCCCGCTCCTTGGAAGT
TAGACATATGAAGAATTGGATCAGAGATTTCTATGACAGTGCGGGAAAGCAGCACTGAGAAACTTTTGATTGTTTTCAATTTCTTCTTTT

>6845_6845_18_ARRB1-PRCP_ARRB1_chr11_75062632_ENST00000420843_PRCP_chr11_82550467_ENST00000535099_length(amino acids)=223AA_BP=34
MARAPPAGWGFSSLGADAADLPATVADHGRQRDPVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQA
CTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ARRB1-PRCP


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneARRB1chr11:75062632chr11:82549616ENST00000360025-11545_866.666666666666667411.0CHRM2
HgeneARRB1chr11:75062632chr11:82549616ENST00000420843-11645_866.666666666666667419.0CHRM2
HgeneARRB1chr11:75062632chr11:82550467ENST00000360025-11545_866.666666666666667411.0CHRM2
HgeneARRB1chr11:75062632chr11:82550467ENST00000420843-11645_866.666666666666667419.0CHRM2
HgeneARRB1chr11:75062632chr11:82549616ENST00000360025-1151_1636.666666666666667411.0SRC
HgeneARRB1chr11:75062632chr11:82549616ENST00000420843-1161_1636.666666666666667419.0SRC
HgeneARRB1chr11:75062632chr11:82550467ENST00000360025-1151_1636.666666666666667411.0SRC
HgeneARRB1chr11:75062632chr11:82550467ENST00000420843-1161_1636.666666666666667419.0SRC
HgeneARRB1chr11:75062632chr11:82549616ENST00000360025-115318_4186.666666666666667411.0TRAF6
HgeneARRB1chr11:75062632chr11:82549616ENST00000420843-116318_4186.666666666666667419.0TRAF6
HgeneARRB1chr11:75062632chr11:82550467ENST00000360025-115318_4186.666666666666667411.0TRAF6
HgeneARRB1chr11:75062632chr11:82550467ENST00000420843-116318_4186.666666666666667419.0TRAF6


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ARRB1-PRCP


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ARRB1-PRCP


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneARRB1C0023890Liver Cirrhosis1CTD_human
HgeneARRB1C0041696Unipolar Depression1PSYGENET
HgeneARRB1C0239946Fibrosis, Liver1CTD_human
HgeneARRB1C1269683Major Depressive Disorder1PSYGENET
HgeneARRB1C3178803Social Anhedonia1PSYGENET