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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:AFF1-PTPN13 (FusionGDB2 ID:HG4299TG5783)

Fusion Gene Summary for AFF1-PTPN13

Fusion gene summary

Fusion gene information	Fusion gene name: AFF1-PTPN13
	Fusion gene ID: hg4299tg5783
		Hgene	Tgene
	Gene symbol	AFF1	PTPN13
	Gene ID	4299	5783
	Gene name	AF4/FMR2 family member 1	protein tyrosine phosphatase non-receptor type 13
	Synonyms	AF4\|MLLT2\|PBM1	FAP-1\|PNP1\|PTP-BAS\|PTP-BL\|PTP1E\|PTPL1\|PTPLE\|hPTP1E
	Cytomap	('AFF1')('PTPN13') 4q21.3-q22.1	4q21.3
	Type of gene	protein-coding	protein-coding
	Description	AF4/FMR2 family member 1ALL1-fused gene from chromosome 4 proteinmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 2pre-B-cell monocytic leukemia partner 1proto-oncogene AF4	tyrosine-protein phosphatase non-receptor type 13fas-associated protein-tyrosine phosphatase 1hPTPE1protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)protein-tyrosine phosphatase 1Eprotein-tyrosine phosphatas
	Modification date	20200313	20200313
	UniProtAcc	P51825	.
	Ensembl transtripts involved in fusion gene	ENST00000511996, ENST00000395146, ENST00000307808, ENST00000544085,	ENST00000511996, ENST00000395146, ENST00000544085, ENST00000307808,
Fusion gene scores	* DoF score	27 X 51 X 13=17901	8 X 13 X 6=624
	# samples	68	15
	** MAII score	log2(68/17901*10)=-4.71836162613835 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(15/624*10)=-2.05658352836637 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: AFF1 [Title/Abstract] AND PTPN13 [Title/Abstract] AND fusion [Title/Abstract] The landscape and therapeutic relevance of cancer-associated transcript fusions (pmid: 25500544)
Most frequent breakpoint	AFF1(87869723)-PTPN13(87556405), # samples:3
Anticipated loss of major functional domain due to fusion event.	AFF1-PTPN13 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. AFF1-PTPN13 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. AFF1-PTPN13 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. AFF1-PTPN13 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. PTPN13-AFF1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. PTPN13-AFF1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. AFF1-PTPN13 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF. AFF1-PTPN13 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. AFF1-PTPN13 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. AFF1-PTPN13 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	PTPN13	GO:0006470	protein dephosphorylation	17657516\|19307596
Tgene	PTPN13	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	23604317

Fusion gene breakpoints across AFF1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PTPN13 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BLCA	TCGA-4Z-AA7Q-01A	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
ChimerDB4	BLCA	TCGA-4Z-AA87-01A	AFF1	chr4	87869723	-	PTPN13	chr4	87718027	+
ChimerDB4	BLCA	TCGA-4Z-AA87	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
ChimerDB4	BLCA	TCGA-4Z-AA87	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
ChimerDB4	BLCA	TCGA-DK-A1AD-01A	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
ChimerDB4	BLCA	TCGA-DK-A1AD-01A	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
ChimerDB4	BLCA	TCGA-DK-A1AD	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
ChimerDB4	BLCA	TCGA-E7-A6MD-01A	AFF1	chr4	88046295	-	PTPN13	chr4	87720254	+
ChimerDB4	BLCA	TCGA-E7-A6MD-01A	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
ChimerDB4	BLCA	TCGA-GC-A3BM-01A	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
ChimerDB4	CESC	TCGA-EA-A5ZD-01A	AFF1	chr4	88048855	-	PTPN13	chr4	87718027	+
ChimerDB4	CESC	TCGA-EA-A5ZD	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
ChimerDB4	LUAD	TCGA-05-4249-01A	AFF1	chr4	87869723	-	PTPN13	chr4	87556405	+
ChimerDB4	LUAD	TCGA-05-4249-01A	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
ChimerDB4	LUSC	TCGA-60-2695-01A	AFF1	chr4	87869723	-	PTPN13	chr4	87556405	+

Top

Fusion Gene ORF analysis for AFF1-PTPN13

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
3UTR-3CDS	ENST00000511996	ENST00000427191	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
3UTR-3CDS	ENST00000511996	ENST00000427191	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
3UTR-3CDS	ENST00000511996	ENST00000427191	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
3UTR-3CDS	ENST00000511996	ENST00000436978	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
3UTR-3CDS	ENST00000511996	ENST00000436978	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
3UTR-3CDS	ENST00000511996	ENST00000436978	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
3UTR-5UTR	ENST00000511996	ENST00000316707	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
3UTR-5UTR	ENST00000511996	ENST00000411767	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
3UTR-5UTR	ENST00000511996	ENST00000427191	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
3UTR-5UTR	ENST00000511996	ENST00000436978	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
3UTR-5UTR	ENST00000511996	ENST00000502971	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
3UTR-5UTR	ENST00000511996	ENST00000511467	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
3UTR-intron	ENST00000511996	ENST00000316707	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
3UTR-intron	ENST00000511996	ENST00000316707	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
3UTR-intron	ENST00000511996	ENST00000316707	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
3UTR-intron	ENST00000511996	ENST00000411767	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
3UTR-intron	ENST00000511996	ENST00000411767	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
3UTR-intron	ENST00000511996	ENST00000411767	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
3UTR-intron	ENST00000511996	ENST00000502971	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
3UTR-intron	ENST00000511996	ENST00000502971	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
3UTR-intron	ENST00000511996	ENST00000502971	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
3UTR-intron	ENST00000511996	ENST00000511467	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
3UTR-intron	ENST00000511996	ENST00000511467	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
3UTR-intron	ENST00000511996	ENST00000511467	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
5CDS-5UTR	ENST00000395146	ENST00000316707	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
5CDS-5UTR	ENST00000395146	ENST00000411767	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
5CDS-5UTR	ENST00000395146	ENST00000427191	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
5CDS-5UTR	ENST00000395146	ENST00000436978	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
5CDS-5UTR	ENST00000395146	ENST00000502971	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
5CDS-5UTR	ENST00000395146	ENST00000511467	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
5CDS-intron	ENST00000307808	ENST00000316707	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000307808	ENST00000316707	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
5CDS-intron	ENST00000307808	ENST00000316707	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
5CDS-intron	ENST00000307808	ENST00000316707	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
5CDS-intron	ENST00000307808	ENST00000316707	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
5CDS-intron	ENST00000307808	ENST00000316707	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000307808	ENST00000411767	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000307808	ENST00000411767	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
5CDS-intron	ENST00000307808	ENST00000411767	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
5CDS-intron	ENST00000307808	ENST00000411767	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
5CDS-intron	ENST00000307808	ENST00000411767	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
5CDS-intron	ENST00000307808	ENST00000411767	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000307808	ENST00000502971	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000307808	ENST00000502971	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
5CDS-intron	ENST00000307808	ENST00000502971	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
5CDS-intron	ENST00000307808	ENST00000502971	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
5CDS-intron	ENST00000307808	ENST00000502971	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
5CDS-intron	ENST00000307808	ENST00000502971	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000307808	ENST00000511467	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000307808	ENST00000511467	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
5CDS-intron	ENST00000307808	ENST00000511467	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
5CDS-intron	ENST00000307808	ENST00000511467	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
5CDS-intron	ENST00000307808	ENST00000511467	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
5CDS-intron	ENST00000307808	ENST00000511467	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000395146	ENST00000316707	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
5CDS-intron	ENST00000395146	ENST00000316707	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000395146	ENST00000316707	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
5CDS-intron	ENST00000395146	ENST00000316707	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
5CDS-intron	ENST00000395146	ENST00000316707	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
5CDS-intron	ENST00000395146	ENST00000316707	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000395146	ENST00000411767	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
5CDS-intron	ENST00000395146	ENST00000411767	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000395146	ENST00000411767	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
5CDS-intron	ENST00000395146	ENST00000411767	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
5CDS-intron	ENST00000395146	ENST00000411767	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
5CDS-intron	ENST00000395146	ENST00000411767	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000395146	ENST00000502971	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
5CDS-intron	ENST00000395146	ENST00000502971	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000395146	ENST00000502971	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
5CDS-intron	ENST00000395146	ENST00000502971	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
5CDS-intron	ENST00000395146	ENST00000502971	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
5CDS-intron	ENST00000395146	ENST00000502971	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000395146	ENST00000511467	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
5CDS-intron	ENST00000395146	ENST00000511467	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000395146	ENST00000511467	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
5CDS-intron	ENST00000395146	ENST00000511467	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
5CDS-intron	ENST00000395146	ENST00000511467	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
5CDS-intron	ENST00000395146	ENST00000511467	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000544085	ENST00000316707	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
5CDS-intron	ENST00000544085	ENST00000316707	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
5CDS-intron	ENST00000544085	ENST00000316707	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000544085	ENST00000411767	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
5CDS-intron	ENST00000544085	ENST00000411767	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
5CDS-intron	ENST00000544085	ENST00000411767	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000544085	ENST00000502971	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
5CDS-intron	ENST00000544085	ENST00000502971	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
5CDS-intron	ENST00000544085	ENST00000502971	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
5CDS-intron	ENST00000544085	ENST00000511467	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
5CDS-intron	ENST00000544085	ENST00000511467	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
5CDS-intron	ENST00000544085	ENST00000511467	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
5UTR-3CDS	ENST00000544085	ENST00000427191	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
5UTR-3CDS	ENST00000544085	ENST00000427191	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
5UTR-3CDS	ENST00000544085	ENST00000427191	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
5UTR-3CDS	ENST00000544085	ENST00000436978	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
5UTR-3CDS	ENST00000544085	ENST00000436978	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
5UTR-3CDS	ENST00000544085	ENST00000436978	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
5UTR-intron	ENST00000544085	ENST00000316707	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
5UTR-intron	ENST00000544085	ENST00000316707	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
5UTR-intron	ENST00000544085	ENST00000316707	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
5UTR-intron	ENST00000544085	ENST00000411767	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
5UTR-intron	ENST00000544085	ENST00000411767	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
5UTR-intron	ENST00000544085	ENST00000411767	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
5UTR-intron	ENST00000544085	ENST00000502971	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
5UTR-intron	ENST00000544085	ENST00000502971	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
5UTR-intron	ENST00000544085	ENST00000502971	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
5UTR-intron	ENST00000544085	ENST00000511467	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
5UTR-intron	ENST00000544085	ENST00000511467	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
5UTR-intron	ENST00000544085	ENST00000511467	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
Frame-shift	ENST00000307808	ENST00000427191	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
Frame-shift	ENST00000307808	ENST00000427191	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
Frame-shift	ENST00000307808	ENST00000427191	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
Frame-shift	ENST00000307808	ENST00000436978	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
Frame-shift	ENST00000307808	ENST00000436978	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
Frame-shift	ENST00000307808	ENST00000436978	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
Frame-shift	ENST00000395146	ENST00000427191	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
Frame-shift	ENST00000395146	ENST00000427191	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
Frame-shift	ENST00000395146	ENST00000427191	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
Frame-shift	ENST00000395146	ENST00000436978	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
Frame-shift	ENST00000395146	ENST00000436978	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
Frame-shift	ENST00000395146	ENST00000436978	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
In-frame	ENST00000307808	ENST00000427191	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
In-frame	ENST00000307808	ENST00000427191	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
In-frame	ENST00000307808	ENST00000427191	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
In-frame	ENST00000307808	ENST00000436978	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
In-frame	ENST00000307808	ENST00000436978	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
In-frame	ENST00000307808	ENST00000436978	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
In-frame	ENST00000395146	ENST00000427191	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
In-frame	ENST00000395146	ENST00000427191	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
In-frame	ENST00000395146	ENST00000427191	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
In-frame	ENST00000395146	ENST00000436978	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
In-frame	ENST00000395146	ENST00000436978	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
In-frame	ENST00000395146	ENST00000436978	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
In-frame	ENST00000544085	ENST00000427191	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
In-frame	ENST00000544085	ENST00000427191	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
In-frame	ENST00000544085	ENST00000427191	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
In-frame	ENST00000544085	ENST00000436978	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
In-frame	ENST00000544085	ENST00000436978	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
In-frame	ENST00000544085	ENST00000436978	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
intron-3CDS	ENST00000307808	ENST00000427191	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
intron-3CDS	ENST00000307808	ENST00000427191	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
intron-3CDS	ENST00000307808	ENST00000427191	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
intron-3CDS	ENST00000307808	ENST00000436978	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
intron-3CDS	ENST00000307808	ENST00000436978	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
intron-3CDS	ENST00000307808	ENST00000436978	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
intron-3CDS	ENST00000395146	ENST00000427191	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
intron-3CDS	ENST00000395146	ENST00000427191	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
intron-3CDS	ENST00000395146	ENST00000427191	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
intron-3CDS	ENST00000395146	ENST00000436978	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
intron-3CDS	ENST00000395146	ENST00000436978	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
intron-3CDS	ENST00000395146	ENST00000436978	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
intron-3CDS	ENST00000511996	ENST00000427191	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
intron-3CDS	ENST00000511996	ENST00000427191	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
intron-3CDS	ENST00000511996	ENST00000427191	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
intron-3CDS	ENST00000511996	ENST00000427191	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
intron-3CDS	ENST00000511996	ENST00000427191	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
intron-3CDS	ENST00000511996	ENST00000427191	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
intron-3CDS	ENST00000511996	ENST00000436978	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
intron-3CDS	ENST00000511996	ENST00000436978	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
intron-3CDS	ENST00000511996	ENST00000436978	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
intron-3CDS	ENST00000511996	ENST00000436978	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
intron-3CDS	ENST00000511996	ENST00000436978	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
intron-3CDS	ENST00000511996	ENST00000436978	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
intron-3CDS	ENST00000544085	ENST00000427191	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
intron-3CDS	ENST00000544085	ENST00000427191	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
intron-3CDS	ENST00000544085	ENST00000427191	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
intron-3CDS	ENST00000544085	ENST00000436978	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
intron-3CDS	ENST00000544085	ENST00000436978	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
intron-3CDS	ENST00000544085	ENST00000436978	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
intron-5UTR	ENST00000307808	ENST00000316707	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
intron-5UTR	ENST00000307808	ENST00000411767	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
intron-5UTR	ENST00000307808	ENST00000427191	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
intron-5UTR	ENST00000307808	ENST00000436978	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
intron-5UTR	ENST00000307808	ENST00000502971	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
intron-5UTR	ENST00000307808	ENST00000511467	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
intron-5UTR	ENST00000544085	ENST00000316707	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
intron-5UTR	ENST00000544085	ENST00000411767	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
intron-5UTR	ENST00000544085	ENST00000427191	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
intron-5UTR	ENST00000544085	ENST00000436978	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
intron-5UTR	ENST00000544085	ENST00000502971	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
intron-5UTR	ENST00000544085	ENST00000511467	AFF1	chr4	87869723	+	PTPN13	chr4	87556405	+
intron-intron	ENST00000307808	ENST00000316707	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
intron-intron	ENST00000307808	ENST00000316707	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
intron-intron	ENST00000307808	ENST00000316707	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
intron-intron	ENST00000307808	ENST00000411767	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
intron-intron	ENST00000307808	ENST00000411767	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
intron-intron	ENST00000307808	ENST00000411767	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
intron-intron	ENST00000307808	ENST00000502971	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
intron-intron	ENST00000307808	ENST00000502971	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
intron-intron	ENST00000307808	ENST00000502971	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
intron-intron	ENST00000307808	ENST00000511467	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
intron-intron	ENST00000307808	ENST00000511467	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
intron-intron	ENST00000307808	ENST00000511467	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
intron-intron	ENST00000395146	ENST00000316707	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
intron-intron	ENST00000395146	ENST00000316707	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
intron-intron	ENST00000395146	ENST00000316707	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
intron-intron	ENST00000395146	ENST00000411767	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
intron-intron	ENST00000395146	ENST00000411767	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
intron-intron	ENST00000395146	ENST00000411767	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
intron-intron	ENST00000395146	ENST00000502971	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
intron-intron	ENST00000395146	ENST00000502971	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
intron-intron	ENST00000395146	ENST00000502971	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
intron-intron	ENST00000395146	ENST00000511467	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
intron-intron	ENST00000395146	ENST00000511467	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
intron-intron	ENST00000395146	ENST00000511467	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
intron-intron	ENST00000511996	ENST00000316707	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
intron-intron	ENST00000511996	ENST00000316707	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
intron-intron	ENST00000511996	ENST00000316707	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
intron-intron	ENST00000511996	ENST00000316707	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
intron-intron	ENST00000511996	ENST00000316707	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
intron-intron	ENST00000511996	ENST00000316707	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
intron-intron	ENST00000511996	ENST00000411767	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
intron-intron	ENST00000511996	ENST00000411767	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
intron-intron	ENST00000511996	ENST00000411767	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
intron-intron	ENST00000511996	ENST00000411767	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
intron-intron	ENST00000511996	ENST00000411767	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
intron-intron	ENST00000511996	ENST00000411767	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
intron-intron	ENST00000511996	ENST00000502971	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
intron-intron	ENST00000511996	ENST00000502971	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
intron-intron	ENST00000511996	ENST00000502971	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
intron-intron	ENST00000511996	ENST00000502971	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
intron-intron	ENST00000511996	ENST00000502971	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
intron-intron	ENST00000511996	ENST00000502971	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
intron-intron	ENST00000511996	ENST00000511467	AFF1	chr4	87928576	-	PTPN13	chr4	87718027	+
intron-intron	ENST00000511996	ENST00000511467	AFF1	chr4	87928576	+	PTPN13	chr4	87637683	+
intron-intron	ENST00000511996	ENST00000511467	AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+
intron-intron	ENST00000511996	ENST00000511467	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+
intron-intron	ENST00000511996	ENST00000511467	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+
intron-intron	ENST00000511996	ENST00000511467	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+
intron-intron	ENST00000544085	ENST00000316707	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
intron-intron	ENST00000544085	ENST00000316707	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
intron-intron	ENST00000544085	ENST00000316707	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
intron-intron	ENST00000544085	ENST00000411767	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
intron-intron	ENST00000544085	ENST00000411767	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
intron-intron	ENST00000544085	ENST00000411767	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
intron-intron	ENST00000544085	ENST00000502971	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
intron-intron	ENST00000544085	ENST00000502971	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
intron-intron	ENST00000544085	ENST00000502971	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+
intron-intron	ENST00000544085	ENST00000511467	AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+
intron-intron	ENST00000544085	ENST00000511467	AFF1	chr4	87869723	+	PTPN13	chr4	87718027	+
intron-intron	ENST00000544085	ENST00000511467	AFF1	chr4	87869723	-	PTPN13	chr4	87637683	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000395146	AFF1	chr4	88046295	+	ENST00000427191	PTPN13	chr4	87720254	+	4511	2848	266	3904	1212
ENST00000395146	AFF1	chr4	88046295	+	ENST00000436978	PTPN13	chr4	87720254	+	4525	2848	266	3904	1212
ENST00000307808	AFF1	chr4	88046295	+	ENST00000427191	PTPN13	chr4	87720254	+	4635	2972	420	4028	1202
ENST00000307808	AFF1	chr4	88046295	+	ENST00000436978	PTPN13	chr4	87720254	+	4649	2972	420	4028	1202
ENST00000544085	AFF1	chr4	88046295	+	ENST00000427191	PTPN13	chr4	87720254	+	3333	1670	132	2726	864
ENST00000544085	AFF1	chr4	88046295	+	ENST00000436978	PTPN13	chr4	87720254	+	3347	1670	132	2726	864
ENST00000395146	AFF1	chr4	88048855	+	ENST00000427191	PTPN13	chr4	87718027	+	4958	3239	266	4351	1361
ENST00000395146	AFF1	chr4	88048855	+	ENST00000436978	PTPN13	chr4	87718027	+	4972	3239	266	4351	1361
ENST00000307808	AFF1	chr4	88048855	+	ENST00000427191	PTPN13	chr4	87718027	+	5082	3363	420	4475	1351
ENST00000307808	AFF1	chr4	88048855	+	ENST00000436978	PTPN13	chr4	87718027	+	5096	3363	420	4475	1351
ENST00000544085	AFF1	chr4	88048855	+	ENST00000427191	PTPN13	chr4	87718027	+	3780	2061	132	3173	1013
ENST00000544085	AFF1	chr4	88048855	+	ENST00000436978	PTPN13	chr4	87718027	+	3794	2061	132	3173	1013
ENST00000395146	AFF1	chr4	88048855	-	ENST00000427191	PTPN13	chr4	87666119	+	8759	3239	266	8152	2628
ENST00000395146	AFF1	chr4	88048855	-	ENST00000436978	PTPN13	chr4	87666119	+	8845	3239	266	8224	2652
ENST00000307808	AFF1	chr4	88048855	-	ENST00000427191	PTPN13	chr4	87666119	+	8883	3363	420	8276	2618
ENST00000307808	AFF1	chr4	88048855	-	ENST00000436978	PTPN13	chr4	87666119	+	8969	3363	420	8348	2642
ENST00000544085	AFF1	chr4	88048855	-	ENST00000427191	PTPN13	chr4	87666119	+	7581	2061	132	6974	2280
ENST00000544085	AFF1	chr4	88048855	-	ENST00000436978	PTPN13	chr4	87666119	+	7667	2061	132	7046	2304

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000395146	ENST00000427191	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+	0.003343949	0.99665606
ENST00000395146	ENST00000436978	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+	0.003301547	0.99669844
ENST00000307808	ENST00000427191	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+	0.003481564	0.9965184
ENST00000307808	ENST00000436978	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+	0.003453241	0.9965468
ENST00000544085	ENST00000427191	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+	0.003110469	0.99688953
ENST00000544085	ENST00000436978	AFF1	chr4	88046295	+	PTPN13	chr4	87720254	+	0.003051666	0.9969483
ENST00000395146	ENST00000427191	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+	0.003704681	0.9962953
ENST00000395146	ENST00000436978	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+	0.003659869	0.99634016
ENST00000307808	ENST00000427191	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+	0.00395229	0.9960477
ENST00000307808	ENST00000436978	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+	0.003904836	0.9960951
ENST00000544085	ENST00000427191	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+	0.00154445	0.9984555
ENST00000544085	ENST00000436978	AFF1	chr4	88048855	+	PTPN13	chr4	87718027	+	0.001513006	0.998487
ENST00000395146	ENST00000427191	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+	0.000802773	0.9991972
ENST00000395146	ENST00000436978	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+	0.000762154	0.9992379
ENST00000307808	ENST00000427191	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+	0.000874989	0.99912506
ENST00000307808	ENST00000436978	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+	0.000836503	0.9991635
ENST00000544085	ENST00000427191	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+	0.000579943	0.99942005
ENST00000544085	ENST00000436978	AFF1	chr4	88048855	-	PTPN13	chr4	87666119	+	0.000550842	0.9994492

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Fusion Genomic Features for AFF1-PTPN13

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
AFF1	chr4	88046295	+	PTPN13	chr4	87720253	+	0.08662497	0.913375
AFF1	chr4	88048855	+	PTPN13	chr4	87718026	+	0.009323893	0.99067605
AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+	7.23E-06	0.9999927
AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+	7.23E-06	0.9999927
AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+	1.64E-08	1
AFF1	chr4	87869723	+	PTPN13	chr4	87556404	+	8.85E-09	1
AFF1	chr4	88046295	+	PTPN13	chr4	87720253	+	0.08662497	0.913375
AFF1	chr4	88048855	+	PTPN13	chr4	87718026	+	0.009323893	0.99067605
AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+	7.23E-06	0.9999927
AFF1	chr4	87928576	+	PTPN13	chr4	87637682	+	7.23E-06	0.9999927
AFF1	chr4	87869723	+	PTPN13	chr4	87718026	+	1.64E-08	1
AFF1	chr4	87869723	+	PTPN13	chr4	87556404	+	8.85E-09	1

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for AFF1-PTPN13

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:87869723/chr4:87556405)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
AFF1 P51825	.
	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

AFF1

chr4:88046295

chr4:87720254

ENST00000307808

483_492

850

1211.0

Compositional bias

Note=Poly-Ser

Hgene

AFF1

chr4:88046295

chr4:87720254

ENST00000307808

835_843

850

1211.0

Compositional bias

Note=Poly-Ser

Hgene

AFF1

chr4:88046295

chr4:87720254

ENST00000395146

483_492

857

1219.0

Compositional bias

Note=Poly-Ser

Hgene

AFF1

chr4:88046295

chr4:87720254

ENST00000395146

835_843

857

1219.0

Compositional bias

Note=Poly-Ser

Hgene

AFF1

chr4:88048855

chr4:87666119

ENST00000307808

483_492

981

1211.0

Compositional bias

Note=Poly-Ser

Hgene

AFF1

chr4:88048855

chr4:87666119

ENST00000307808

835_843

981

1211.0

Compositional bias

Note=Poly-Ser

Hgene

AFF1

chr4:88048855

chr4:87666119

ENST00000307808

866_869

981

1211.0

Compositional bias

Note=Poly-Pro

Hgene

AFF1

chr4:88048855

chr4:87666119

ENST00000307808

871_874

981

1211.0

Compositional bias

Note=Poly-Ser

Hgene

AFF1

chr4:88048855

chr4:87666119

ENST00000395146

483_492

988

1219.0

Compositional bias

Note=Poly-Ser

Hgene

AFF1

chr4:88048855

chr4:87666119

ENST00000395146

835_843

988

1219.0

Compositional bias

Note=Poly-Ser

Hgene

AFF1

chr4:88048855

chr4:87666119

ENST00000395146

866_869

988

1219.0

Compositional bias

Note=Poly-Pro

Hgene

AFF1

chr4:88048855

chr4:87666119

ENST00000395146

871_874

988

1219.0

Compositional bias

Note=Poly-Ser

Hgene

AFF1

chr4:88048855

chr4:87718027

ENST00000307808

483_492

981

1211.0

Compositional bias

Note=Poly-Ser

Hgene

AFF1

chr4:88048855

chr4:87718027

ENST00000307808

835_843

981

1211.0

Compositional bias

Note=Poly-Ser

Hgene

AFF1

chr4:88048855

chr4:87718027

ENST00000307808

866_869

981

1211.0

Compositional bias

Note=Poly-Pro

Hgene

AFF1

chr4:88048855

chr4:87718027

ENST00000307808

871_874

981

1211.0

Compositional bias

Note=Poly-Ser

Hgene

AFF1

chr4:88048855

chr4:87718027

ENST00000395146

483_492

988

1219.0

Compositional bias

Note=Poly-Ser

Hgene

AFF1

chr4:88048855

chr4:87718027

ENST00000395146

835_843

988

1219.0

Compositional bias

Note=Poly-Ser

Hgene

AFF1

chr4:88048855

chr4:87718027

ENST00000395146

866_869

988

1219.0

Compositional bias

Note=Poly-Pro

Hgene

AFF1

chr4:88048855

chr4:87718027

ENST00000395146

871_874

988

1219.0

Compositional bias

Note=Poly-Ser

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000316707

1742_1749

829

2295.0

Compositional bias

Note=Poly-Ser

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000411767

1742_1749

829

2486.0

Compositional bias

Note=Poly-Ser

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000427191

1742_1749

829

2467.0

Compositional bias

Note=Poly-Ser

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000436978

1742_1749

829

2491.0

Compositional bias

Note=Poly-Ser

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000511467

1742_1749

829

2491.0

Compositional bias

Note=Poly-Ser

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000316707

2213_2467

1942

2295.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000411767

2213_2467

2133

2486.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000427191

2213_2467

2114

2467.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000436978

2213_2467

2138

2491.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000511467

2213_2467

2138

2491.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000316707

1093_1178

829

2295.0

Domain

PDZ 1

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000316707

1368_1452

829

2295.0

Domain

PDZ 2

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000316707

1501_1588

829

2295.0

Domain

PDZ 3

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000316707

1788_1868

829

2295.0

Domain

PDZ 4

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000316707

1882_1965

829

2295.0

Domain

PDZ 5

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000316707

2213_2467

829

2295.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000411767

1093_1178

829

2486.0

Domain

PDZ 1

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000411767

1368_1452

829

2486.0

Domain

PDZ 2

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000411767

1501_1588

829

2486.0

Domain

PDZ 3

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000411767

1788_1868

829

2486.0

Domain

PDZ 4

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000411767

1882_1965

829

2486.0

Domain

PDZ 5

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000411767

2213_2467

829

2486.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000427191

1093_1178

829

2467.0

Domain

PDZ 1

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000427191

1368_1452

829

2467.0

Domain

PDZ 2

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000427191

1501_1588

829

2467.0

Domain

PDZ 3

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000427191

1788_1868

829

2467.0

Domain

PDZ 4

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000427191

1882_1965

829

2467.0

Domain

PDZ 5

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000427191

2213_2467

829

2467.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000436978

1093_1178

829

2491.0

Domain

PDZ 1

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000436978

1368_1452

829

2491.0

Domain

PDZ 2

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000436978

1501_1588

829

2491.0

Domain

PDZ 3

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000436978

1788_1868

829

2491.0

Domain

PDZ 4

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000436978

1882_1965

829

2491.0

Domain

PDZ 5

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000436978

2213_2467

829

2491.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000511467

1093_1178

829

2491.0

Domain

PDZ 1

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000511467

1368_1452

829

2491.0

Domain

PDZ 2

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000511467

1501_1588

829

2491.0

Domain

PDZ 3

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000511467

1788_1868

829

2491.0

Domain

PDZ 4

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000511467

1882_1965

829

2491.0

Domain

PDZ 5

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000511467

2213_2467

829

2491.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000316707

2213_2467

1924

2295.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000411767

2213_2467

2115

2486.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000427191

2213_2467

2096

2467.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000436978

2213_2467

2120

2491.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000511467

2213_2467

2120

2491.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000316707

2408_2414

1942

2295.0

Region

Substrate binding

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000411767

2408_2414

2133

2486.0

Region

Substrate binding

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000427191

2408_2414

2114

2467.0

Region

Substrate binding

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000436978

2408_2414

2138

2491.0

Region

Substrate binding

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000511467

2408_2414

2138

2491.0

Region

Substrate binding

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000316707

2408_2414

829

2295.0

Region

Substrate binding

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000411767

2408_2414

829

2486.0

Region

Substrate binding

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000427191

2408_2414

829

2467.0

Region

Substrate binding

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000436978

2408_2414

829

2491.0

Region

Substrate binding

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000511467

2408_2414

829

2491.0

Region

Substrate binding

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000316707

2408_2414

1924

2295.0

Region

Substrate binding

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000411767

2408_2414

2115

2486.0

Region

Substrate binding

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000427191

2408_2414

2096

2467.0

Region

Substrate binding

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000436978

2408_2414

2120

2491.0

Region

Substrate binding

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000511467

2408_2414

2120

2491.0

Region

Substrate binding

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

AFF1

chr4:88046295

chr4:87720254

ENST00000307808

866_869

850

1211.0

Compositional bias

Note=Poly-Pro

Hgene

AFF1

chr4:88046295

chr4:87720254

ENST00000307808

871_874

850

1211.0

Compositional bias

Note=Poly-Ser

Hgene

AFF1

chr4:88046295

chr4:87720254

ENST00000395146

866_869

857

1219.0

Compositional bias

Note=Poly-Pro

Hgene

AFF1

chr4:88046295

chr4:87720254

ENST00000395146

871_874

857

1219.0

Compositional bias

Note=Poly-Ser

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000316707

469_504

1942

2295.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000411767

469_504

2133

2486.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000427191

469_504

2114

2467.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000436978

469_504

2138

2491.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000511467

469_504

2138

2491.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000316707

469_504

829

2295.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000411767

469_504

829

2486.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000427191

469_504

829

2467.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000436978

469_504

829

2491.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000511467

469_504

829

2491.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000316707

469_504

1924

2295.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000411767

469_504

2115

2486.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000427191

469_504

2096

2467.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000436978

469_504

2120

2491.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000511467

469_504

2120

2491.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000316707

1742_1749

1942

2295.0

Compositional bias

Note=Poly-Ser

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000316707

56_59

1942

2295.0

Compositional bias

Note=Poly-Leu

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000411767

1742_1749

2133

2486.0

Compositional bias

Note=Poly-Ser

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000411767

56_59

2133

2486.0

Compositional bias

Note=Poly-Leu

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000427191

1742_1749

2114

2467.0

Compositional bias

Note=Poly-Ser

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000427191

56_59

2114

2467.0

Compositional bias

Note=Poly-Leu

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000436978

1742_1749

2138

2491.0

Compositional bias

Note=Poly-Ser

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000436978

56_59

2138

2491.0

Compositional bias

Note=Poly-Leu

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000511467

1742_1749

2138

2491.0

Compositional bias

Note=Poly-Ser

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000511467

56_59

2138

2491.0

Compositional bias

Note=Poly-Leu

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000316707

56_59

829

2295.0

Compositional bias

Note=Poly-Leu

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000411767

56_59

829

2486.0

Compositional bias

Note=Poly-Leu

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000427191

56_59

829

2467.0

Compositional bias

Note=Poly-Leu

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000436978

56_59

829

2491.0

Compositional bias

Note=Poly-Leu

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000511467

56_59

829

2491.0

Compositional bias

Note=Poly-Leu

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000316707

1742_1749

1924

2295.0

Compositional bias

Note=Poly-Ser

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000316707

56_59

1924

2295.0

Compositional bias

Note=Poly-Leu

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000411767

1742_1749

2115

2486.0

Compositional bias

Note=Poly-Ser

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000411767

56_59

2115

2486.0

Compositional bias

Note=Poly-Leu

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000427191

1742_1749

2096

2467.0

Compositional bias

Note=Poly-Ser

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000427191

56_59

2096

2467.0

Compositional bias

Note=Poly-Leu

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000436978

1742_1749

2120

2491.0

Compositional bias

Note=Poly-Ser

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000436978

56_59

2120

2491.0

Compositional bias

Note=Poly-Leu

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000511467

1742_1749

2120

2491.0

Compositional bias

Note=Poly-Ser

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000511467

56_59

2120

2491.0

Compositional bias

Note=Poly-Leu

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000316707

1093_1178

1942

2295.0

Domain

PDZ 1

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000316707

1368_1452

1942

2295.0

Domain

PDZ 2

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000316707

1501_1588

1942

2295.0

Domain

PDZ 3

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000316707

1788_1868

1942

2295.0

Domain

PDZ 4

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000316707

1882_1965

1942

2295.0

Domain

PDZ 5

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000316707

3_190

1942

2295.0

Domain

KIND

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000316707

572_872

1942

2295.0

Domain

FERM

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000411767

1093_1178

2133

2486.0

Domain

PDZ 1

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000411767

1368_1452

2133

2486.0

Domain

PDZ 2

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000411767

1501_1588

2133

2486.0

Domain

PDZ 3

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000411767

1788_1868

2133

2486.0

Domain

PDZ 4

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000411767

1882_1965

2133

2486.0

Domain

PDZ 5

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000411767

3_190

2133

2486.0

Domain

KIND

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000411767

572_872

2133

2486.0

Domain

FERM

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000427191

1093_1178

2114

2467.0

Domain

PDZ 1

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000427191

1368_1452

2114

2467.0

Domain

PDZ 2

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000427191

1501_1588

2114

2467.0

Domain

PDZ 3

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000427191

1788_1868

2114

2467.0

Domain

PDZ 4

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000427191

1882_1965

2114

2467.0

Domain

PDZ 5

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000427191

3_190

2114

2467.0

Domain

KIND

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000427191

572_872

2114

2467.0

Domain

FERM

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000436978

1093_1178

2138

2491.0

Domain

PDZ 1

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000436978

1368_1452

2138

2491.0

Domain

PDZ 2

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000436978

1501_1588

2138

2491.0

Domain

PDZ 3

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000436978

1788_1868

2138

2491.0

Domain

PDZ 4

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000436978

1882_1965

2138

2491.0

Domain

PDZ 5

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000436978

3_190

2138

2491.0

Domain

KIND

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000436978

572_872

2138

2491.0

Domain

FERM

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000511467

1093_1178

2138

2491.0

Domain

PDZ 1

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000511467

1368_1452

2138

2491.0

Domain

PDZ 2

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000511467

1501_1588

2138

2491.0

Domain

PDZ 3

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000511467

1788_1868

2138

2491.0

Domain

PDZ 4

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000511467

1882_1965

2138

2491.0

Domain

PDZ 5

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000511467

3_190

2138

2491.0

Domain

KIND

Tgene

PTPN13

chr4:88046295

chr4:87720254

ENST00000511467

572_872

2138

2491.0

Domain

FERM

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000316707

3_190

829

2295.0

Domain

KIND

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000316707

572_872

829

2295.0

Domain

FERM

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000411767

3_190

829

2486.0

Domain

KIND

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000411767

572_872

829

2486.0

Domain

FERM

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000427191

3_190

829

2467.0

Domain

KIND

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000427191

572_872

829

2467.0

Domain

FERM

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000436978

3_190

829

2491.0

Domain

KIND

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000436978

572_872

829

2491.0

Domain

FERM

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000511467

3_190

829

2491.0

Domain

KIND

Tgene

PTPN13

chr4:88048855

chr4:87666119

ENST00000511467

572_872

829

2491.0

Domain

FERM

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000316707

1093_1178

1924

2295.0

Domain

PDZ 1

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000316707

1368_1452

1924

2295.0

Domain

PDZ 2

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000316707

1501_1588

1924

2295.0

Domain

PDZ 3

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000316707

1788_1868

1924

2295.0

Domain

PDZ 4

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000316707

1882_1965

1924

2295.0

Domain

PDZ 5

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000316707

3_190

1924

2295.0

Domain

KIND

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000316707

572_872

1924

2295.0

Domain

FERM

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000411767

1093_1178

2115

2486.0

Domain

PDZ 1

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000411767

1368_1452

2115

2486.0

Domain

PDZ 2

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000411767

1501_1588

2115

2486.0

Domain

PDZ 3

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000411767

1788_1868

2115

2486.0

Domain

PDZ 4

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000411767

1882_1965

2115

2486.0

Domain

PDZ 5

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000411767

3_190

2115

2486.0

Domain

KIND

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000411767

572_872

2115

2486.0

Domain

FERM

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000427191

1093_1178

2096

2467.0

Domain

PDZ 1

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000427191

1368_1452

2096

2467.0

Domain

PDZ 2

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000427191

1501_1588

2096

2467.0

Domain

PDZ 3

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000427191

1788_1868

2096

2467.0

Domain

PDZ 4

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000427191

1882_1965

2096

2467.0

Domain

PDZ 5

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000427191

3_190

2096

2467.0

Domain

KIND

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000427191

572_872

2096

2467.0

Domain

FERM

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000436978

1093_1178

2120

2491.0

Domain

PDZ 1

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000436978

1368_1452

2120

2491.0

Domain

PDZ 2

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000436978

1501_1588

2120

2491.0

Domain

PDZ 3

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000436978

1788_1868

2120

2491.0

Domain

PDZ 4

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000436978

1882_1965

2120

2491.0

Domain

PDZ 5

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000436978

3_190

2120

2491.0

Domain

KIND

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000436978

572_872

2120

2491.0

Domain

FERM

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000511467

1093_1178

2120

2491.0

Domain

PDZ 1

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000511467

1368_1452

2120

2491.0

Domain

PDZ 2

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000511467

1501_1588

2120

2491.0

Domain

PDZ 3

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000511467

1788_1868

2120

2491.0

Domain

PDZ 4

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000511467

1882_1965

2120

2491.0

Domain

PDZ 5

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000511467

3_190

2120

2491.0

Domain

KIND

Tgene

PTPN13

chr4:88048855

chr4:87718027

ENST00000511467

572_872

2120

2491.0

Domain

FERM

Top

Fusion Gene Sequence for AFF1-PTPN13

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>2666_2666_1_AFF1-PTPN13_AFF1_chr4_88046295_ENST00000307808_PTPN13_chr4_87720254_ENST00000427191_length(transcript)=4635nt_BP=2972nt
GGCAATTTCTTTTCCTTTCTAACTGTGGCCCGCGTTGTGCTGTTGCTGGGCAGGCGTTGGGCGCCGGCGGTCTTCGAGCGTGGGGGCCCG
CTGGCTTTCCCTTCTCAGAAACTGCGCCGGGGGCGCTCGCTTGCCCCGGATTCGGACGCGGCGCTCCCCGGGCTCGTCTGAAGTGCAGAT
CGCCGCAGAGGCCCCAGTGCCCGGATGTCCATCAGGATTAGCGCGAGCCAATACGGGCCGAGCCCGGGGCTGCGCCGAGGACGCCCGGGG
CTCGAGAGCAGGTAGTCCCGTAACATCGGGGCGCCGCGCCGGGACGCGTCCCCGCCCGGCTCCGCCAAATGGTGAGCGCGGCGCTGGCAG
CAGGGCCCGCGGGGTGAAGGCGCTCATGGACGGAAGACCCCTGGCTCTATAAGCTGAATTATGGCAGCCCAGTCAAGTTTGTACAATGAC
GACAGAAACCTGCTTCGAATTAGAGAGAAGGAAAGACGCAACCAGGAAGCCCACCAAGAGAAAGAGGCATTTCCTGAAAAGATTCCCCTT
TTTGGAGAGCCCTACAAGACAGCAAAAGGTGATGAGCTGTCTAGTCGAATACAGAACATGTTGGGAAACTACGAAGAAGTGAAGGAGTTC
CTTAGTACTAAGTCTCACACTCATCGCCTGGATGCTTCTGAAAATAGGTTGGGAAAGCCGAAATATCCTTTAATTCCTGACAAAGGGAGC
AGCATTCCATCCAGCTCCTTCCACACTAGTGTCCACCACCAGTCCATTCACACTCCTGCGTCTGGACCACTTTCTGTTGGCAACATTAGC
CACAATCCAAAGATGGCGCAGCCAAGAACTGAACCAATGCCAAGTCTCCATGCCAAAAGCTGCGGCCCACCGGACAGCCAGCACCTGACC
CAGGATCGCCTTGGTCAGGAGGGGTTCGGCTCTAGTCATCACAAGAAAGGTGACCGAAGAGCTGACGGAGACCACTGTGCTTCGGTGACA
GATTCGGCTCCAGAGAGGGAGCTTTCTCCCTTAATCTCTTTGCCTTCCCCAGTTCCCCCTTTGTCACCTATACATTCCAACCAGCAAACT
CTTCCCCGGACGCAAGGAAGCAGCAAGGTTCATGGCAGCAGCAATAACAGTAAAGGCTATTGCCCAGCCAAATCTCCCAAGGACCTAGCA
GTGAAAGTCCATGATAAAGAGACCCCTCAAGACAGTTTGGTGGCCCCTGCCCAGCCGCCTTCTCAGACATTTCCACCTCCCTCCCTCCCC
TCAAAAAGTGTTGCAATGCAGCAGAAGCCCACGGCTTATGTCCGGCCCATGGATGGTCAAGATCAGGCCCCTAGTGAATCCCCTGAACTG
AAACCACTGCCGGAGGACTATCGACAGCAGACCTTTGAAAAAACAGACTTGAAAGTGCCTGCCAAAGCCAAGCTCACCAAACTGAAGATG
CCTTCTCAGTCAGTTGAGCAGACCTACTCCAATGAAGTCCATTGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCT
TTGACAGCAATACATACGCCTAGTACAGCTGAGCCATCCAAGTTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAA
AACCAAAAACAATATGATACATCTTCAAAAACTCACTCAAATTCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGT
GACAGTGAGGACAGTGACAGTGAACAAACCCCAGAGAAGCCTCCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCA
GTGGCATCAGCACATTCCAGCAGTGCAGAGTCAGAAAGCACCAGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGT
GACAGCGAAGAAAATGAGCCCCTAGAAACCCCAGCTCCGGAGCCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACC
AAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCCCCAGGAGCACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGT
GCCACGAGTCAGGAGCATTCTGAATCCAAAGATCCTCCCCCTAAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCC
GGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGCAGGAGCCCCCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAG
GCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGCAGGGGGAAAGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAA
GACAAGCCCAAGGTGAAGACGAAAGGACGGCCCCGGGCCGCAGCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAG
AAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGGCTCTCTCAGGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCAC
TTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCCCACCCCACAGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTC
CAGGAGGACAGCCGCAAAGACAGACTCCCATTGCCTTTGAGAGACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGC
TTGATGGTGAAGATCACCCTAGACCTGCTCTCTCGGATACCCCAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAG
CCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGAGGAGCTCAGACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGA
GACTGTGATAACAAGAAAATCAGACTGGAGAAGGAAATCAAATCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACA
AACTTAATTCAGAAGCCACAAGAAAAGAAGACTGATGATGATGAAATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCAT
GAAGATTCTGATAAAGATCATTCCTTTCTGACAAACGATGAGCTCGCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACG
GGTGCCAACTTAAAATCAGTCATTCGAGTCCTGCGGGGTTTGCTAGATCAAGGAATTCCTTCTAAGGAGCTGGAGAATCTTCAAGAATTA
AAACCTTTGGATCAGTGTCTAATTGGGCAAACTAAGGAAAACAGAAGGAAGAACAGATATAAAAATATACTTCCCTATGATGCTACAAGA
GTGCCTCTTGGAGATGAAGGTGGCTATATCAATGCCAGCTTCATTAAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAA
GGACCACTGCCTACAACTGTTGGAGACTTCTGGCAGATGATTTGGGAGCAAAAATCCACAGTGATAGCCATGATGACTCAAGAAGTAGAA
GGAGAAAAAATCAAATGCCAGCGCTATTGGCCCAACATCCTAGGCAAAACAACAATGGTCAGCAACAGACTTCGACTGGCTCTTGTGAGA
ATGCAGCAGCTGAAGGGCTTTGTGGTGAGGGCAATGACCCTTGAAGATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTC
ACTGCCTGGCCAGACCATGATACACCTTCTCAACCAGATGATCTGCTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCA
ATCATTACGCACTGCAGTGCTGGCATTGGACGTTCAGGGACCCTGATTTGCATAGATGTGGTTCTGGGATTAATCAGTCAGGATCTTGAT
TTTGACATCTCTGATTTGGTGCGCTGCATGAGACTACAAAGACACGGAATGGTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTC
ATCCTTTATGTCCTGACACGTCTTCAAGCAGAAGAAGAGCAAAAACAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATG
CATTTCCATTTCTCTCCTTAACCTCCAGCAGACTCCTGCTCTCTATCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGCATG
TTCTCCTCTATCTTAGAGGGGTATTCTTCTTGAAAATAAAAAATATTGAAATGCTGTATTTTTACAGCTACTTTAACCTATGATAATTAT
TTACAAAATTTTAACACTAACCAAACAATGCAGATCTTAGGGATGATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACAT
GGTGAGTCTATTTTTAATGCACCAATCTTGTTTATAGCAAAAATGTTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTG
AAACCAGTATTTAAGCTTTAAATGACAGTAATATTGGCATAGAAAAAAGTAGCAAATGTTTACTGTATCAATTTCTAATGTTTACTATAT
AGAATTTCCTGTAATATATTTATATACTTTTTCATGAAAATGGAGTTATCAGTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATT
ATCTCACTTTGTAAATAAAAACACACCTTAAAACATGAACAAGCC

>2666_2666_1_AFF1-PTPN13_AFF1_chr4_88046295_ENST00000307808_PTPN13_chr4_87720254_ENST00000427191_length(amino acids)=1202AA_BP=851
MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP
KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR
ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP
SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEIL
KEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAP
PSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRR
HPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLL
PYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSR
TSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKL
AKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTNLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFLTNDELAVLPV
VKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVG
KEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTR
EVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQT
EDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK

--------------------------------------------------------------
>2666_2666_2_AFF1-PTPN13_AFF1_chr4_88046295_ENST00000307808_PTPN13_chr4_87720254_ENST00000436978_length(transcript)=4649nt_BP=2972nt
GGCAATTTCTTTTCCTTTCTAACTGTGGCCCGCGTTGTGCTGTTGCTGGGCAGGCGTTGGGCGCCGGCGGTCTTCGAGCGTGGGGGCCCG
CTGGCTTTCCCTTCTCAGAAACTGCGCCGGGGGCGCTCGCTTGCCCCGGATTCGGACGCGGCGCTCCCCGGGCTCGTCTGAAGTGCAGAT
CGCCGCAGAGGCCCCAGTGCCCGGATGTCCATCAGGATTAGCGCGAGCCAATACGGGCCGAGCCCGGGGCTGCGCCGAGGACGCCCGGGG
CTCGAGAGCAGGTAGTCCCGTAACATCGGGGCGCCGCGCCGGGACGCGTCCCCGCCCGGCTCCGCCAAATGGTGAGCGCGGCGCTGGCAG
CAGGGCCCGCGGGGTGAAGGCGCTCATGGACGGAAGACCCCTGGCTCTATAAGCTGAATTATGGCAGCCCAGTCAAGTTTGTACAATGAC
GACAGAAACCTGCTTCGAATTAGAGAGAAGGAAAGACGCAACCAGGAAGCCCACCAAGAGAAAGAGGCATTTCCTGAAAAGATTCCCCTT
TTTGGAGAGCCCTACAAGACAGCAAAAGGTGATGAGCTGTCTAGTCGAATACAGAACATGTTGGGAAACTACGAAGAAGTGAAGGAGTTC
CTTAGTACTAAGTCTCACACTCATCGCCTGGATGCTTCTGAAAATAGGTTGGGAAAGCCGAAATATCCTTTAATTCCTGACAAAGGGAGC
AGCATTCCATCCAGCTCCTTCCACACTAGTGTCCACCACCAGTCCATTCACACTCCTGCGTCTGGACCACTTTCTGTTGGCAACATTAGC
CACAATCCAAAGATGGCGCAGCCAAGAACTGAACCAATGCCAAGTCTCCATGCCAAAAGCTGCGGCCCACCGGACAGCCAGCACCTGACC
CAGGATCGCCTTGGTCAGGAGGGGTTCGGCTCTAGTCATCACAAGAAAGGTGACCGAAGAGCTGACGGAGACCACTGTGCTTCGGTGACA
GATTCGGCTCCAGAGAGGGAGCTTTCTCCCTTAATCTCTTTGCCTTCCCCAGTTCCCCCTTTGTCACCTATACATTCCAACCAGCAAACT
CTTCCCCGGACGCAAGGAAGCAGCAAGGTTCATGGCAGCAGCAATAACAGTAAAGGCTATTGCCCAGCCAAATCTCCCAAGGACCTAGCA
GTGAAAGTCCATGATAAAGAGACCCCTCAAGACAGTTTGGTGGCCCCTGCCCAGCCGCCTTCTCAGACATTTCCACCTCCCTCCCTCCCC
TCAAAAAGTGTTGCAATGCAGCAGAAGCCCACGGCTTATGTCCGGCCCATGGATGGTCAAGATCAGGCCCCTAGTGAATCCCCTGAACTG
AAACCACTGCCGGAGGACTATCGACAGCAGACCTTTGAAAAAACAGACTTGAAAGTGCCTGCCAAAGCCAAGCTCACCAAACTGAAGATG
CCTTCTCAGTCAGTTGAGCAGACCTACTCCAATGAAGTCCATTGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCT
TTGACAGCAATACATACGCCTAGTACAGCTGAGCCATCCAAGTTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAA
AACCAAAAACAATATGATACATCTTCAAAAACTCACTCAAATTCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGT
GACAGTGAGGACAGTGACAGTGAACAAACCCCAGAGAAGCCTCCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCA
GTGGCATCAGCACATTCCAGCAGTGCAGAGTCAGAAAGCACCAGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGT
GACAGCGAAGAAAATGAGCCCCTAGAAACCCCAGCTCCGGAGCCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACC
AAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCCCCAGGAGCACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGT
GCCACGAGTCAGGAGCATTCTGAATCCAAAGATCCTCCCCCTAAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCC
GGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGCAGGAGCCCCCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAG
GCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGCAGGGGGAAAGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAA
GACAAGCCCAAGGTGAAGACGAAAGGACGGCCCCGGGCCGCAGCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAG
AAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGGCTCTCTCAGGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCAC
TTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCCCACCCCACAGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTC
CAGGAGGACAGCCGCAAAGACAGACTCCCATTGCCTTTGAGAGACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGC
TTGATGGTGAAGATCACCCTAGACCTGCTCTCTCGGATACCCCAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAG
CCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGAGGAGCTCAGACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGA
GACTGTGATAACAAGAAAATCAGACTGGAGAAGGAAATCAAATCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACA
AACTTAATTCAGAAGCCACAAGAAAAGAAGACTGATGATGATGAAATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCAT
GAAGATTCTGATAAAGATCATTCCTTTCTGACAAACGATGAGCTCGCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACG
GGTGCCAACTTAAAATCAGTCATTCGAGTCCTGCGGGGTTTGCTAGATCAAGGAATTCCTTCTAAGGAGCTGGAGAATCTTCAAGAATTA
AAACCTTTGGATCAGTGTCTAATTGGGCAAACTAAGGAAAACAGAAGGAAGAACAGATATAAAAATATACTTCCCTATGATGCTACAAGA
GTGCCTCTTGGAGATGAAGGTGGCTATATCAATGCCAGCTTCATTAAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAA
GGACCACTGCCTACAACTGTTGGAGACTTCTGGCAGATGATTTGGGAGCAAAAATCCACAGTGATAGCCATGATGACTCAAGAAGTAGAA
GGAGAAAAAATCAAATGCCAGCGCTATTGGCCCAACATCCTAGGCAAAACAACAATGGTCAGCAACAGACTTCGACTGGCTCTTGTGAGA
ATGCAGCAGCTGAAGGGCTTTGTGGTGAGGGCAATGACCCTTGAAGATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTC
ACTGCCTGGCCAGACCATGATACACCTTCTCAACCAGATGATCTGCTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCA
ATCATTACGCACTGCAGTGCTGGCATTGGACGTTCAGGGACCCTGATTTGCATAGATGTGGTTCTGGGATTAATCAGTCAGGATCTTGAT
TTTGACATCTCTGATTTGGTGCGCTGCATGAGACTACAAAGACACGGAATGGTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTC
ATCCTTTATGTCCTGACACGTCTTCAAGCAGAAGAAGAGCAAAAACAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATG
CATTTCCATTTCTCTCCTTAACCTCCAGCAGACTCCTGCTCTCTATCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGCATG
TTCTCCTCTATCTTAGAGGGGTATTCTTCTTGAAAATAAAAAATATTGAAATGCTGTATTTTTACAGCTACTTTAACCTATGATAATTAT
TTACAAAATTTTAACACTAACCAAACAATGCAGATCTTAGGGATGATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACAT
GGTGAGTCTATTTTTAATGCACCAATCTTGTTTATAGCAAAAATGTTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTG
AAACCAGTATTTAAGCTTTAAATGACAGTAATATTGGCATAGAAAAAAGTAGCAAATGTTTACTGTATCAATTTCTAATGTTTACTATAT
AGAATTTCCTGTAATATATTTATATACTTTTTCATGAAAATGGAGTTATCAGTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATT
ATCTCACTTTGTAAATAAAAACACACCTTAAAACATGAACAAGCCAAAACTGTGTGCAG

>2666_2666_2_AFF1-PTPN13_AFF1_chr4_88046295_ENST00000307808_PTPN13_chr4_87720254_ENST00000436978_length(amino acids)=1202AA_BP=851
MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP
KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR
ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP
SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEIL
KEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAP
PSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRR
HPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLL
PYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSR
TSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKL
AKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTNLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFLTNDELAVLPV
VKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVG
KEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTR
EVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQT
EDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK

--------------------------------------------------------------
>2666_2666_3_AFF1-PTPN13_AFF1_chr4_88046295_ENST00000395146_PTPN13_chr4_87720254_ENST00000427191_length(transcript)=4511nt_BP=2848nt
GAGCTTGCCAGCCAGCTAGCGAGCGACGGGCGCGCGCGGCCCCTGCGCACTCGGCCGCCGCCTGCGCGCGTTGCGGCCGCAGCTGCACCT
TTGCCTCCGCGGTTCCGCAGCCGAGCCCCGGGAGGAGGCGCTCCCCTGCGTCGTCCGCACTTGCGCCCTTTCCCACCGCAACAGGTCAGG
GGAGGGCGGAGGTGACGAGGGCGCCCGACCCGGGACTAGAGGACGGAAGGGTCTGGAAGATGAACAGACTAGCCACTTTGCATTGACTGG
AAACAATGGCATTTACAGAAAGAGTCAACAGCAGTGGCAACAGTTTGTACAATGACGACAGAAACCTGCTTCGAATTAGAGAGAAGGAAA
GACGCAACCAGGAAGCCCACCAAGAGAAAGAGGCATTTCCTGAAAAGATTCCCCTTTTTGGAGAGCCCTACAAGACAGCAAAAGGTGATG
AGCTGTCTAGTCGAATACAGAACATGTTGGGAAACTACGAAGAAGTGAAGGAGTTCCTTAGTACTAAGTCTCACACTCATCGCCTGGATG
CTTCTGAAAATAGGTTGGGAAAGCCGAAATATCCTTTAATTCCTGACAAAGGGAGCAGCATTCCATCCAGCTCCTTCCACACTAGTGTCC
ACCACCAGTCCATTCACACTCCTGCGTCTGGACCACTTTCTGTTGGCAACATTAGCCACAATCCAAAGATGGCGCAGCCAAGAACTGAAC
CAATGCCAAGTCTCCATGCCAAAAGCTGCGGCCCACCGGACAGCCAGCACCTGACCCAGGATCGCCTTGGTCAGGAGGGGTTCGGCTCTA
GTCATCACAAGAAAGGTGACCGAAGAGCTGACGGAGACCACTGTGCTTCGGTGACAGATTCGGCTCCAGAGAGGGAGCTTTCTCCCTTAA
TCTCTTTGCCTTCCCCAGTTCCCCCTTTGTCACCTATACATTCCAACCAGCAAACTCTTCCCCGGACGCAAGGAAGCAGCAAGGTTCATG
GCAGCAGCAATAACAGTAAAGGCTATTGCCCAGCCAAATCTCCCAAGGACCTAGCAGTGAAAGTCCATGATAAAGAGACCCCTCAAGACA
GTTTGGTGGCCCCTGCCCAGCCGCCTTCTCAGACATTTCCACCTCCCTCCCTCCCCTCAAAAAGTGTTGCAATGCAGCAGAAGCCCACGG
CTTATGTCCGGCCCATGGATGGTCAAGATCAGGCCCCTAGTGAATCCCCTGAACTGAAACCACTGCCGGAGGACTATCGACAGCAGACCT
TTGAAAAAACAGACTTGAAAGTGCCTGCCAAAGCCAAGCTCACCAAACTGAAGATGCCTTCTCAGTCAGTTGAGCAGACCTACTCCAATG
AAGTCCATTGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCTTTGACAGCAATACATACGCCTAGTACAGCTGAGC
CATCCAAGTTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAAAACCAAAAACAATATGATACATCTTCAAAAACTC
ACTCAAATTCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGTGACAGTGAGGACAGTGACAGTGAACAAACCCCAG
AGAAGCCTCCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCAGTGGCATCAGCACATTCCAGCAGTGCAGAGTCAG
AAAGCACCAGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGTGACAGCGAAGAAAATGAGCCCCTAGAAACCCCAG
CTCCGGAGCCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACCAAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCC
CCAGGAGCACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGTGCCACGAGTCAGGAGCATTCTGAATCCAAAGATC
CTCCCCCTAAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCCGGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGC
AGGAGCCCCCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAGGCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGC
AGGGGGAAAGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAAGACAAGCCCAAGGTGAAGACGAAAGGACGGCCCC
GGGCCGCAGCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAGAAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGG
CTCTCTCAGGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCACTTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCC
CACCCCACAGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTCCAGGAGGACAGCCGCAAAGACAGACTCCCATTGC
CTTTGAGAGACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGCTTGATGGTGAAGATCACCCTAGACCTGCTCTCTC
GGATACCCCAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAGCCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGA
GGAGCTCAGACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGAGACTGTGATAACAAGAAAATCAGACTGGAGAAGG
AAATCAAATCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACAAACTTAATTCAGAAGCCACAAGAAAAGAAGACTG
ATGATGATGAAATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCATGAAGATTCTGATAAAGATCATTCCTTTCTGACAA
ACGATGAGCTCGCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACGGGTGCCAACTTAAAATCAGTCATTCGAGTCCTGC
GGGGTTTGCTAGATCAAGGAATTCCTTCTAAGGAGCTGGAGAATCTTCAAGAATTAAAACCTTTGGATCAGTGTCTAATTGGGCAAACTA
AGGAAAACAGAAGGAAGAACAGATATAAAAATATACTTCCCTATGATGCTACAAGAGTGCCTCTTGGAGATGAAGGTGGCTATATCAATG
CCAGCTTCATTAAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAAGGACCACTGCCTACAACTGTTGGAGACTTCTGGC
AGATGATTTGGGAGCAAAAATCCACAGTGATAGCCATGATGACTCAAGAAGTAGAAGGAGAAAAAATCAAATGCCAGCGCTATTGGCCCA
ACATCCTAGGCAAAACAACAATGGTCAGCAACAGACTTCGACTGGCTCTTGTGAGAATGCAGCAGCTGAAGGGCTTTGTGGTGAGGGCAA
TGACCCTTGAAGATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTCACTGCCTGGCCAGACCATGATACACCTTCTCAAC
CAGATGATCTGCTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCAATCATTACGCACTGCAGTGCTGGCATTGGACGTT
CAGGGACCCTGATTTGCATAGATGTGGTTCTGGGATTAATCAGTCAGGATCTTGATTTTGACATCTCTGATTTGGTGCGCTGCATGAGAC
TACAAAGACACGGAATGGTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTCATCCTTTATGTCCTGACACGTCTTCAAGCAGAAG
AAGAGCAAAAACAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATGCATTTCCATTTCTCTCCTTAACCTCCAGCAGACT
CCTGCTCTCTATCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGCATGTTCTCCTCTATCTTAGAGGGGTATTCTTCTTGAA
AATAAAAAATATTGAAATGCTGTATTTTTACAGCTACTTTAACCTATGATAATTATTTACAAAATTTTAACACTAACCAAACAATGCAGA
TCTTAGGGATGATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACATGGTGAGTCTATTTTTAATGCACCAATCTTGTTTA
TAGCAAAAATGTTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTGAAACCAGTATTTAAGCTTTAAATGACAGTAATAT
TGGCATAGAAAAAAGTAGCAAATGTTTACTGTATCAATTTCTAATGTTTACTATATAGAATTTCCTGTAATATATTTATATACTTTTTCA
TGAAAATGGAGTTATCAGTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATTATCTCACTTTGTAAATAAAAACACACCTTAAAAC
ATGAACAAGCC

>2666_2666_3_AFF1-PTPN13_AFF1_chr4_88046295_ENST00000395146_PTPN13_chr4_87720254_ENST00000427191_length(amino acids)=1212AA_BP=861
METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL
DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG
SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ
DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYS
NEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQT
PEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPE
GPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTS
LQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQ
GPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSE
KRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTNLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFL
TNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYI
NASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVR
AMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCM
RLQRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK

--------------------------------------------------------------
>2666_2666_4_AFF1-PTPN13_AFF1_chr4_88046295_ENST00000395146_PTPN13_chr4_87720254_ENST00000436978_length(transcript)=4525nt_BP=2848nt
GAGCTTGCCAGCCAGCTAGCGAGCGACGGGCGCGCGCGGCCCCTGCGCACTCGGCCGCCGCCTGCGCGCGTTGCGGCCGCAGCTGCACCT
TTGCCTCCGCGGTTCCGCAGCCGAGCCCCGGGAGGAGGCGCTCCCCTGCGTCGTCCGCACTTGCGCCCTTTCCCACCGCAACAGGTCAGG
GGAGGGCGGAGGTGACGAGGGCGCCCGACCCGGGACTAGAGGACGGAAGGGTCTGGAAGATGAACAGACTAGCCACTTTGCATTGACTGG
AAACAATGGCATTTACAGAAAGAGTCAACAGCAGTGGCAACAGTTTGTACAATGACGACAGAAACCTGCTTCGAATTAGAGAGAAGGAAA
GACGCAACCAGGAAGCCCACCAAGAGAAAGAGGCATTTCCTGAAAAGATTCCCCTTTTTGGAGAGCCCTACAAGACAGCAAAAGGTGATG
AGCTGTCTAGTCGAATACAGAACATGTTGGGAAACTACGAAGAAGTGAAGGAGTTCCTTAGTACTAAGTCTCACACTCATCGCCTGGATG
CTTCTGAAAATAGGTTGGGAAAGCCGAAATATCCTTTAATTCCTGACAAAGGGAGCAGCATTCCATCCAGCTCCTTCCACACTAGTGTCC
ACCACCAGTCCATTCACACTCCTGCGTCTGGACCACTTTCTGTTGGCAACATTAGCCACAATCCAAAGATGGCGCAGCCAAGAACTGAAC
CAATGCCAAGTCTCCATGCCAAAAGCTGCGGCCCACCGGACAGCCAGCACCTGACCCAGGATCGCCTTGGTCAGGAGGGGTTCGGCTCTA
GTCATCACAAGAAAGGTGACCGAAGAGCTGACGGAGACCACTGTGCTTCGGTGACAGATTCGGCTCCAGAGAGGGAGCTTTCTCCCTTAA
TCTCTTTGCCTTCCCCAGTTCCCCCTTTGTCACCTATACATTCCAACCAGCAAACTCTTCCCCGGACGCAAGGAAGCAGCAAGGTTCATG
GCAGCAGCAATAACAGTAAAGGCTATTGCCCAGCCAAATCTCCCAAGGACCTAGCAGTGAAAGTCCATGATAAAGAGACCCCTCAAGACA
GTTTGGTGGCCCCTGCCCAGCCGCCTTCTCAGACATTTCCACCTCCCTCCCTCCCCTCAAAAAGTGTTGCAATGCAGCAGAAGCCCACGG
CTTATGTCCGGCCCATGGATGGTCAAGATCAGGCCCCTAGTGAATCCCCTGAACTGAAACCACTGCCGGAGGACTATCGACAGCAGACCT
TTGAAAAAACAGACTTGAAAGTGCCTGCCAAAGCCAAGCTCACCAAACTGAAGATGCCTTCTCAGTCAGTTGAGCAGACCTACTCCAATG
AAGTCCATTGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCTTTGACAGCAATACATACGCCTAGTACAGCTGAGC
CATCCAAGTTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAAAACCAAAAACAATATGATACATCTTCAAAAACTC
ACTCAAATTCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGTGACAGTGAGGACAGTGACAGTGAACAAACCCCAG
AGAAGCCTCCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCAGTGGCATCAGCACATTCCAGCAGTGCAGAGTCAG
AAAGCACCAGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGTGACAGCGAAGAAAATGAGCCCCTAGAAACCCCAG
CTCCGGAGCCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACCAAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCC
CCAGGAGCACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGTGCCACGAGTCAGGAGCATTCTGAATCCAAAGATC
CTCCCCCTAAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCCGGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGC
AGGAGCCCCCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAGGCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGC
AGGGGGAAAGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAAGACAAGCCCAAGGTGAAGACGAAAGGACGGCCCC
GGGCCGCAGCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAGAAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGG
CTCTCTCAGGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCACTTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCC
CACCCCACAGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTCCAGGAGGACAGCCGCAAAGACAGACTCCCATTGC
CTTTGAGAGACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGCTTGATGGTGAAGATCACCCTAGACCTGCTCTCTC
GGATACCCCAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAGCCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGA
GGAGCTCAGACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGAGACTGTGATAACAAGAAAATCAGACTGGAGAAGG
AAATCAAATCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACAAACTTAATTCAGAAGCCACAAGAAAAGAAGACTG
ATGATGATGAAATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCATGAAGATTCTGATAAAGATCATTCCTTTCTGACAA
ACGATGAGCTCGCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACGGGTGCCAACTTAAAATCAGTCATTCGAGTCCTGC
GGGGTTTGCTAGATCAAGGAATTCCTTCTAAGGAGCTGGAGAATCTTCAAGAATTAAAACCTTTGGATCAGTGTCTAATTGGGCAAACTA
AGGAAAACAGAAGGAAGAACAGATATAAAAATATACTTCCCTATGATGCTACAAGAGTGCCTCTTGGAGATGAAGGTGGCTATATCAATG
CCAGCTTCATTAAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAAGGACCACTGCCTACAACTGTTGGAGACTTCTGGC
AGATGATTTGGGAGCAAAAATCCACAGTGATAGCCATGATGACTCAAGAAGTAGAAGGAGAAAAAATCAAATGCCAGCGCTATTGGCCCA
ACATCCTAGGCAAAACAACAATGGTCAGCAACAGACTTCGACTGGCTCTTGTGAGAATGCAGCAGCTGAAGGGCTTTGTGGTGAGGGCAA
TGACCCTTGAAGATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTCACTGCCTGGCCAGACCATGATACACCTTCTCAAC
CAGATGATCTGCTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCAATCATTACGCACTGCAGTGCTGGCATTGGACGTT
CAGGGACCCTGATTTGCATAGATGTGGTTCTGGGATTAATCAGTCAGGATCTTGATTTTGACATCTCTGATTTGGTGCGCTGCATGAGAC
TACAAAGACACGGAATGGTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTCATCCTTTATGTCCTGACACGTCTTCAAGCAGAAG
AAGAGCAAAAACAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATGCATTTCCATTTCTCTCCTTAACCTCCAGCAGACT
CCTGCTCTCTATCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGCATGTTCTCCTCTATCTTAGAGGGGTATTCTTCTTGAA
AATAAAAAATATTGAAATGCTGTATTTTTACAGCTACTTTAACCTATGATAATTATTTACAAAATTTTAACACTAACCAAACAATGCAGA
TCTTAGGGATGATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACATGGTGAGTCTATTTTTAATGCACCAATCTTGTTTA
TAGCAAAAATGTTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTGAAACCAGTATTTAAGCTTTAAATGACAGTAATAT
TGGCATAGAAAAAAGTAGCAAATGTTTACTGTATCAATTTCTAATGTTTACTATATAGAATTTCCTGTAATATATTTATATACTTTTTCA
TGAAAATGGAGTTATCAGTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATTATCTCACTTTGTAAATAAAAACACACCTTAAAAC
ATGAACAAGCCAAAACTGTGTGCAG

>2666_2666_4_AFF1-PTPN13_AFF1_chr4_88046295_ENST00000395146_PTPN13_chr4_87720254_ENST00000436978_length(amino acids)=1212AA_BP=861
METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL
DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG
SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ
DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYS
NEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQT
PEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPE
GPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTS
LQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQ
GPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSE
KRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTNLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFL
TNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYI
NASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVR
AMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCM
RLQRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK

--------------------------------------------------------------
>2666_2666_5_AFF1-PTPN13_AFF1_chr4_88046295_ENST00000544085_PTPN13_chr4_87720254_ENST00000427191_length(transcript)=3333nt_BP=1670nt
GTAGTCCCGTAACATCGGGGCGCCGCGCCGGGACGCGTCCCCGCCCGGCTCCGCCAAATGGTGAGCGCGGCGCTGGCAGCAGGGCCCGCG
GGGTGAAGGCGCTCATGGACGGAAGACCCCTGGCTCTATAAGCTGAATTATGGCAGCCCAGTCAAGCAGACCTACTCCAATGAAGTCCAT
TGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCTTTGACAGCAATACATACGCCTAGTACAGCTGAGCCATCCAAG
TTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAAAACCAAAAACAATATGATACATCTTCAAAAACTCACTCAAAT
TCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGTGACAGTGAGGACAGTGACAGTGAACAAACCCCAGAGAAGCCT
CCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCAGTGGCATCAGCACATTCCAGCAGTGCAGAGTCAGAAAGCACC
AGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGTGACAGCGAAGAAAATGAGCCCCTAGAAACCCCAGCTCCGGAG
CCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACCAAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCCCCAGGAGC
ACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGTGCCACGAGTCAGGAGCATTCTGAATCCAAAGATCCTCCCCCT
AAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCCGGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGCAGGAGCCC
CCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAGGCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGCAGGGGGAA
AGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAAGACAAGCCCAAGGTGAAGACGAAAGGACGGCCCCGGGCCGCA
GCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAGAAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGGCTCTCTCA
GGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCACTTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCCCACCCCAC
AGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTCCAGGAGGACAGCCGCAAAGACAGACTCCCATTGCCTTTGAGA
GACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGCTTGATGGTGAAGATCACCCTAGACCTGCTCTCTCGGATACCC
CAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAGCCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGAGGAGCTCA
GACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGAGACTGTGATAACAAGAAAATCAGACTGGAGAAGGAAATCAAA
TCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACAAACTTAATTCAGAAGCCACAAGAAAAGAAGACTGATGATGAT
GAAATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCATGAAGATTCTGATAAAGATCATTCCTTTCTGACAAACGATGAG
CTCGCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACGGGTGCCAACTTAAAATCAGTCATTCGAGTCCTGCGGGGTTTG
CTAGATCAAGGAATTCCTTCTAAGGAGCTGGAGAATCTTCAAGAATTAAAACCTTTGGATCAGTGTCTAATTGGGCAAACTAAGGAAAAC
AGAAGGAAGAACAGATATAAAAATATACTTCCCTATGATGCTACAAGAGTGCCTCTTGGAGATGAAGGTGGCTATATCAATGCCAGCTTC
ATTAAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAAGGACCACTGCCTACAACTGTTGGAGACTTCTGGCAGATGATT
TGGGAGCAAAAATCCACAGTGATAGCCATGATGACTCAAGAAGTAGAAGGAGAAAAAATCAAATGCCAGCGCTATTGGCCCAACATCCTA
GGCAAAACAACAATGGTCAGCAACAGACTTCGACTGGCTCTTGTGAGAATGCAGCAGCTGAAGGGCTTTGTGGTGAGGGCAATGACCCTT
GAAGATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTCACTGCCTGGCCAGACCATGATACACCTTCTCAACCAGATGAT
CTGCTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCAATCATTACGCACTGCAGTGCTGGCATTGGACGTTCAGGGACC
CTGATTTGCATAGATGTGGTTCTGGGATTAATCAGTCAGGATCTTGATTTTGACATCTCTGATTTGGTGCGCTGCATGAGACTACAAAGA
CACGGAATGGTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTCATCCTTTATGTCCTGACACGTCTTCAAGCAGAAGAAGAGCAA
AAACAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATGCATTTCCATTTCTCTCCTTAACCTCCAGCAGACTCCTGCTCT
CTATCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGCATGTTCTCCTCTATCTTAGAGGGGTATTCTTCTTGAAAATAAAAA
ATATTGAAATGCTGTATTTTTACAGCTACTTTAACCTATGATAATTATTTACAAAATTTTAACACTAACCAAACAATGCAGATCTTAGGG
ATGATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACATGGTGAGTCTATTTTTAATGCACCAATCTTGTTTATAGCAAAA
ATGTTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTGAAACCAGTATTTAAGCTTTAAATGACAGTAATATTGGCATAG
AAAAAAGTAGCAAATGTTTACTGTATCAATTTCTAATGTTTACTATATAGAATTTCCTGTAATATATTTATATACTTTTTCATGAAAATG
GAGTTATCAGTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATTATCTCACTTTGTAAATAAAAACACACCTTAAAACATGAACAA
GCC

>2666_2666_5_AFF1-PTPN13_AFF1_chr4_88046295_ENST00000544085_PTPN13_chr4_87720254_ENST00000427191_length(amino acids)=864AA_BP=513
MNYGSPVKQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQ
LSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNW
LTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKP
VKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTP
EHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAED
KQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTNLIQKPQEKKTDDDEITWGNDELPIERT
NHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDA
TRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLAL
VRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQD
LDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK

--------------------------------------------------------------
>2666_2666_6_AFF1-PTPN13_AFF1_chr4_88046295_ENST00000544085_PTPN13_chr4_87720254_ENST00000436978_length(transcript)=3347nt_BP=1670nt
GTAGTCCCGTAACATCGGGGCGCCGCGCCGGGACGCGTCCCCGCCCGGCTCCGCCAAATGGTGAGCGCGGCGCTGGCAGCAGGGCCCGCG
GGGTGAAGGCGCTCATGGACGGAAGACCCCTGGCTCTATAAGCTGAATTATGGCAGCCCAGTCAAGCAGACCTACTCCAATGAAGTCCAT
TGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCTTTGACAGCAATACATACGCCTAGTACAGCTGAGCCATCCAAG
TTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAAAACCAAAAACAATATGATACATCTTCAAAAACTCACTCAAAT
TCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGTGACAGTGAGGACAGTGACAGTGAACAAACCCCAGAGAAGCCT
CCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCAGTGGCATCAGCACATTCCAGCAGTGCAGAGTCAGAAAGCACC
AGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGTGACAGCGAAGAAAATGAGCCCCTAGAAACCCCAGCTCCGGAG
CCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACCAAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCCCCAGGAGC
ACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGTGCCACGAGTCAGGAGCATTCTGAATCCAAAGATCCTCCCCCT
AAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCCGGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGCAGGAGCCC
CCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAGGCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGCAGGGGGAA
AGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAAGACAAGCCCAAGGTGAAGACGAAAGGACGGCCCCGGGCCGCA
GCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAGAAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGGCTCTCTCA
GGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCACTTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCCCACCCCAC
AGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTCCAGGAGGACAGCCGCAAAGACAGACTCCCATTGCCTTTGAGA
GACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGCTTGATGGTGAAGATCACCCTAGACCTGCTCTCTCGGATACCC
CAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAGCCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGAGGAGCTCA
GACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGAGACTGTGATAACAAGAAAATCAGACTGGAGAAGGAAATCAAA
TCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACAAACTTAATTCAGAAGCCACAAGAAAAGAAGACTGATGATGAT
GAAATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCATGAAGATTCTGATAAAGATCATTCCTTTCTGACAAACGATGAG
CTCGCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACGGGTGCCAACTTAAAATCAGTCATTCGAGTCCTGCGGGGTTTG
CTAGATCAAGGAATTCCTTCTAAGGAGCTGGAGAATCTTCAAGAATTAAAACCTTTGGATCAGTGTCTAATTGGGCAAACTAAGGAAAAC
AGAAGGAAGAACAGATATAAAAATATACTTCCCTATGATGCTACAAGAGTGCCTCTTGGAGATGAAGGTGGCTATATCAATGCCAGCTTC
ATTAAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAAGGACCACTGCCTACAACTGTTGGAGACTTCTGGCAGATGATT
TGGGAGCAAAAATCCACAGTGATAGCCATGATGACTCAAGAAGTAGAAGGAGAAAAAATCAAATGCCAGCGCTATTGGCCCAACATCCTA
GGCAAAACAACAATGGTCAGCAACAGACTTCGACTGGCTCTTGTGAGAATGCAGCAGCTGAAGGGCTTTGTGGTGAGGGCAATGACCCTT
GAAGATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTCACTGCCTGGCCAGACCATGATACACCTTCTCAACCAGATGAT
CTGCTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCAATCATTACGCACTGCAGTGCTGGCATTGGACGTTCAGGGACC
CTGATTTGCATAGATGTGGTTCTGGGATTAATCAGTCAGGATCTTGATTTTGACATCTCTGATTTGGTGCGCTGCATGAGACTACAAAGA
CACGGAATGGTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTCATCCTTTATGTCCTGACACGTCTTCAAGCAGAAGAAGAGCAA
AAACAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATGCATTTCCATTTCTCTCCTTAACCTCCAGCAGACTCCTGCTCT
CTATCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGCATGTTCTCCTCTATCTTAGAGGGGTATTCTTCTTGAAAATAAAAA
ATATTGAAATGCTGTATTTTTACAGCTACTTTAACCTATGATAATTATTTACAAAATTTTAACACTAACCAAACAATGCAGATCTTAGGG
ATGATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACATGGTGAGTCTATTTTTAATGCACCAATCTTGTTTATAGCAAAA
ATGTTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTGAAACCAGTATTTAAGCTTTAAATGACAGTAATATTGGCATAG
AAAAAAGTAGCAAATGTTTACTGTATCAATTTCTAATGTTTACTATATAGAATTTCCTGTAATATATTTATATACTTTTTCATGAAAATG
GAGTTATCAGTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATTATCTCACTTTGTAAATAAAAACACACCTTAAAACATGAACAA
GCCAAAACTGTGTGCAG

>2666_2666_6_AFF1-PTPN13_AFF1_chr4_88046295_ENST00000544085_PTPN13_chr4_87720254_ENST00000436978_length(amino acids)=864AA_BP=513
MNYGSPVKQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQ
LSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNW
LTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKP
VKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTP
EHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAED
KQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTNLIQKPQEKKTDDDEITWGNDELPIERT
NHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDA
TRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLAL
VRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQD
LDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK

--------------------------------------------------------------
>2666_2666_7_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000307808_PTPN13_chr4_87666119_ENST00000427191_length(transcript)=8883nt_BP=3363nt
GGCAATTTCTTTTCCTTTCTAACTGTGGCCCGCGTTGTGCTGTTGCTGGGCAGGCGTTGGGCGCCGGCGGTCTTCGAGCGTGGGGGCCCG
CTGGCTTTCCCTTCTCAGAAACTGCGCCGGGGGCGCTCGCTTGCCCCGGATTCGGACGCGGCGCTCCCCGGGCTCGTCTGAAGTGCAGAT
CGCCGCAGAGGCCCCAGTGCCCGGATGTCCATCAGGATTAGCGCGAGCCAATACGGGCCGAGCCCGGGGCTGCGCCGAGGACGCCCGGGG
CTCGAGAGCAGGTAGTCCCGTAACATCGGGGCGCCGCGCCGGGACGCGTCCCCGCCCGGCTCCGCCAAATGGTGAGCGCGGCGCTGGCAG
CAGGGCCCGCGGGGTGAAGGCGCTCATGGACGGAAGACCCCTGGCTCTATAAGCTGAATTATGGCAGCCCAGTCAAGTTTGTACAATGAC
GACAGAAACCTGCTTCGAATTAGAGAGAAGGAAAGACGCAACCAGGAAGCCCACCAAGAGAAAGAGGCATTTCCTGAAAAGATTCCCCTT
TTTGGAGAGCCCTACAAGACAGCAAAAGGTGATGAGCTGTCTAGTCGAATACAGAACATGTTGGGAAACTACGAAGAAGTGAAGGAGTTC
CTTAGTACTAAGTCTCACACTCATCGCCTGGATGCTTCTGAAAATAGGTTGGGAAAGCCGAAATATCCTTTAATTCCTGACAAAGGGAGC
AGCATTCCATCCAGCTCCTTCCACACTAGTGTCCACCACCAGTCCATTCACACTCCTGCGTCTGGACCACTTTCTGTTGGCAACATTAGC
CACAATCCAAAGATGGCGCAGCCAAGAACTGAACCAATGCCAAGTCTCCATGCCAAAAGCTGCGGCCCACCGGACAGCCAGCACCTGACC
CAGGATCGCCTTGGTCAGGAGGGGTTCGGCTCTAGTCATCACAAGAAAGGTGACCGAAGAGCTGACGGAGACCACTGTGCTTCGGTGACA
GATTCGGCTCCAGAGAGGGAGCTTTCTCCCTTAATCTCTTTGCCTTCCCCAGTTCCCCCTTTGTCACCTATACATTCCAACCAGCAAACT
CTTCCCCGGACGCAAGGAAGCAGCAAGGTTCATGGCAGCAGCAATAACAGTAAAGGCTATTGCCCAGCCAAATCTCCCAAGGACCTAGCA
GTGAAAGTCCATGATAAAGAGACCCCTCAAGACAGTTTGGTGGCCCCTGCCCAGCCGCCTTCTCAGACATTTCCACCTCCCTCCCTCCCC
TCAAAAAGTGTTGCAATGCAGCAGAAGCCCACGGCTTATGTCCGGCCCATGGATGGTCAAGATCAGGCCCCTAGTGAATCCCCTGAACTG
AAACCACTGCCGGAGGACTATCGACAGCAGACCTTTGAAAAAACAGACTTGAAAGTGCCTGCCAAAGCCAAGCTCACCAAACTGAAGATG
CCTTCTCAGTCAGTTGAGCAGACCTACTCCAATGAAGTCCATTGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCT
TTGACAGCAATACATACGCCTAGTACAGCTGAGCCATCCAAGTTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAA
AACCAAAAACAATATGATACATCTTCAAAAACTCACTCAAATTCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGT
GACAGTGAGGACAGTGACAGTGAACAAACCCCAGAGAAGCCTCCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCA
GTGGCATCAGCACATTCCAGCAGTGCAGAGTCAGAAAGCACCAGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGT
GACAGCGAAGAAAATGAGCCCCTAGAAACCCCAGCTCCGGAGCCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACC
AAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCCCCAGGAGCACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGT
GCCACGAGTCAGGAGCATTCTGAATCCAAAGATCCTCCCCCTAAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCC
GGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGCAGGAGCCCCCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAG
GCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGCAGGGGGAAAGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAA
GACAAGCCCAAGGTGAAGACGAAAGGACGGCCCCGGGCCGCAGCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAG
AAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGGCTCTCTCAGGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCAC
TTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCCCACCCCACAGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTC
CAGGAGGACAGCCGCAAAGACAGACTCCCATTGCCTTTGAGAGACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGC
TTGATGGTGAAGATCACCCTAGACCTGCTCTCTCGGATACCCCAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAG
CCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGAGGAGCTCAGACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGA
GACTGTGATAACAAGAAAATCAGACTGGAGAAGGAAATCAAATCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACA
AAGCCCTCCAGGCCCTCCTCACAGTCCTCAAAGAAGGAAATGCTCCCCCCGCCACCCGTGTCCTCGTCCTCCCAGAAGCCAGCCAAGCCT
GCACTTAAGAGGTCAAGGCGGGAAGCAGACACCTGTGGCCAGGACCCTCCCAAAAGTGCCAGCAGTACCAAGAGCAACCACAAAGACTCT
TCCATTCCCAAGCAGAGAAGAGTAGAGGGGAAGGGCTCCAGAAGCTCCTCGGAGCACAAGGGTTCTTCCGGAGATACTGCAAATCCTTTT
CCAGTGCCTTCTTTGCCAAATGGTAACTCTAAACCAGGGAAGCCTCAAGTGAAGTTTGACAAACAACAAGCAGACCTTCACATGAGGGAG
GCAAAAAAGATGAAGCAGAAAGCAGAGTTAATGAAAAAGAAAATCACATTGCAAAATACATCAGATGGAATAAAACATGGCTTCCAGACA
GACAACAGTAAGATATGCCAGTACCTGCTGCACCTCTGCTCTTACCAGCATAAGTTCCAGCTACAGATGAGAGCAAGACAGAGCAACCAA
GATGCCCAAGATATTGAGAGAGCTTCGTTTAGGAGCCTGAATCTCCAAGCAGAGTCTGTTAGAGGATTTAATATGGGACGAGCAATCAGC
ACTGGCAGTCTGGCCAGCAGCACCCTCAACAAACTTGCTGTTCGACCTTTATCAGTTCAAGCTGAGATTCTGAAGAGGCTATCCTGCTCA
GAGCTGTCGCTTTACCAGCCATTGCAAAACAGTTCAAAAGAGAAGAATGACAAAGCTTCATGGGAGGAAAAGCCTAGAGAGATGAGTAAA
TCATACCATGATCTCAGTCAGGCCTCTCTCTATCCACATCGGAAAAATGTCATTGTTAACATGGAACCCCCACCACAAACCGTTGCAGAG
TTGGTGGGAAAACCTTCTCACCAGATGTCAAGATCTGATGCAGAATCTTTGGCAGGAGTGACAAAACTTAATAATTCAAAGTCTGTTGCG
AGTTTAAATAGAAGTCCTGAAAGGAGGAAACATGAATCAGACTCCTCATCCATTGAAGACCCTGGGCAAGCATATGTTCTAGATGTGCTA
CACAAAAGATGGAGCATAGTATCTTCACCAGAAAGGGAGATCACCTTAGTGAACCTGAAAAAAGATGCAAAGTATGGCTTGGGATTTCAA
ATTATTGGTGGGGAGAAGATGGGAAGACTGGACCTAGGCATATTTATCAGTTCAGTTGCCCCTGGAGGACCAGCTGACTTGGATGGATGC
TTGAAGCCAGGAGACCGTTTGATATCTGTGAATAGTGTGAGTCTGGAGGGAGTCAGCCACCATGCTGCAATTGAAATTTTGCAAAATGCA
CCTGAAGATGTGACACTTGTTATCTCTCAGCCAAAAGAAAAGATATCCAAAGTGCCTTCTACTCCTGTGCATCTCACCAATGAGATGAAA
AACTACATGAAGAAATCTTCCTACATGCAAGACAGTGCTATAGATTCTTCTTCCAAGGATCACCACTGGTCACGTGGTACCCTGAGGCAC
ATCTCGGAGAACTCCTTTGGGCCATCTGGGGGCCTGCGGGAAGGAAGCCTGAGTTCTCAAGATTCCAGGACTGAGAGTGCCAGCTTGTCT
CAAAGCCAGGTCAATGGTTTCTTTGCCAGCCATTTAGGTGACCAAACCTGGCAGGAATCACAGCATGGCAGCCCTTCCCCATCTGTAATA
TCCAAAGCCACCGAGAAAGAGACTTTCACTGATAGTAACCAAAGCAAAACTAAAAAGCCAGGCATTTCTGATGTAACTGATTACTCAGAC
CGTGGAGATTCAGACATGGATGAAGCCACTTACTCCAGCAGTCAGGATCATCAAACACCAAAACAGGAATCTTCCTCTTCAGTGAATACA
TCCAACAAGATGAATTTTAAAACTTTTTCTTCATCACCTCCTAAGCCTGGAGATATCTTTGAGGTTGAACTGGCTAAAAATGATAACAGC
TTGGGGATAAGTGTCACGGGAGGTGTGAATACGAGTGTCAGACATGGTGGCATTTATGTGAAAGCTGTTATTCCCCAGGGAGCAGCAGAG
TCTGATGGTAGAATTCACAAAGGTGATCGCGTCCTAGCTGTCAATGGAGTTAGTCTAGAAGGAGCCACCCATAAGCAAGCTGTGGAAACA
CTGAGAAATACAGGACAGGTGGTTCATCTGTTATTAGAAAAGGGACAATCTCCAACATCTAAAGAACATGTCCCGGTAACCCCACAGTGT
ACCCTTTCAGATCAGAATGCCCAAGGTCAAGGCCCAGAAAAAGTGAAGAAAACAACTCAGGTCAAAGACTACAGCTTTGTCACTGAAGAA
AATACATTTGAGGTAAAATTATTTAAAAATAGCTCAGGTCTAGGATTCAGTTTTTCTCGAGAAGATAATCTTATACCGGAGCAAATTAAT
GCCAGCATAGTAAGGGTTAAAAAGCTCTTTCCTGGACAGCCAGCAGCAGAAAGTGGAAAAATTGATGTAGGAGATGTTATCTTGAAAGTG
AATGGAGCCTCTTTGAAAGGACTATCTCAGCAGGAAGTCATATCTGCTCTCAGGGGAACTGCTCCAGAAGTATTCTTGCTTCTCTGCAGA
CCTCCACCTGGTGTGCTACCGGAAATTGATACTGCGCTTTTGACCCCACTTCAGTCTCCAGCACAAGTACTTCCAAACAGCAGTAAAGAC
TCTTCTCAGCCATCATGTGTGGAGCAAAGCACCAGCTCAGATGAAAATGAAATGTCAGACAAAAGCAAAAAACAGTGCAAGTCCCCATCC
AGAAGAGACAGTTACAGTGACAGCAGTGGGAGTGGAGAAGATGACTTAGTGACAGCTCCAGCAAACATATCAAATTCGACCTGGAGTTCA
GCTTTGCATCAGACTCTAAGCAACATGGTATCACAGGCACAGAGTCATCATGAAGCACCCAAGAGTCAAGAAGATACCATTTGTACCATG
TTTTACTATCCTCAGAAAATTCCCAATAAACCAGAGTTTGAGGACAGTAATCCTTCCCCTCTACCACCGGATATGGCTCCTGGGCAGAGT
TATCAACCCCAATCAGAATCTGCTTCCTCTAGTTCGATGGATAAGTATCATATACATCACATTTCTGAACCAACTAGACAAGAAAACTGG
ACACCTTTGAAAAATGACTTGGAAAATCACCTTGAAGACTTTGAACTGGAAGTAGAACTCCTCATTACCCTAATTAAATCAGAAAAAGGA
AGCCTGGGTTTTACAGTAACCAAAGGCAATCAGAGAATTGGTTGTTATGTTCATGATGTCATACAGGATCCAGCCAAAAGTGATGGAAGG
CTAAAACCTGGGGACCGGCTCATAAAGGTTAATGATACAGATGTTACTAATATGACTCATACAGATGCAGTTAATCTGCTCCGGGCTGCA
TCCAAAACAGTCAGATTAGTTATTGGACGAGTTCTAGAATTACCCAGAATACCAATGTTGCCTCATTTGCTACCGGACATAACACTAACG
TGCAACAAAGAGGAGTTGGGTTTTTCCTTATGTGGAGGTCATGACAGCCTTTATCAAGTGGTATATATTAGTGATATTAATCCAAGGTCC
GTCGCAGCCATTGAGGGTAATCTCCAGCTATTAGATGTCATCCATTATGTGAACGGAGTCAGCACACAAGGAATGACCTTGGAGGAAGTT
AACAGAGCATTAGACATGTCACTTCCTTCATTGGTATTGAAAGCAACAAGAAATGATCTTCCAGTGGTCCCCAGCTCAAAGAGGTCTGCT
GTTTCAGCTCCAAAGTCAACCAAAGGCAATGGTTCCTACAGTGTGGGGTCTTGCAGCCAGCCTGCCCTCACTCCTAATGATTCATTCTCC
ACGGTTGCTGGGGAAGAAATAAATGAAATATCGTACCCCAAAGGAAAATGTTCTACTTATCAGATAAAGGGATCACCAAACTTGACTCTG
CCCAAAGAATCTTATATACAAGAAGATGACATTTATGATGATTCCCAAGAAGCTGAAGTTATCCAGTCTCTGCTGGATGTTGTGGATGAG
GAAGCCCAGAATCTTTTAAACGAAAATAATGCAGCAGGATACTCCTGTGGTCCAGGTACATTAAAGATGAATGGGAAGTTATCAGAAGAG
AGAACAGAAGATACAGACTGCGATGGTTCACCTTTACCTGAGTATTTTACTGAGGCCACCAAAATGAATGGCTGTGAAGAATATTGTGAA
GAAAAAGTAAAAAGTGAAAGCTTAATTCAGAAGCCACAAGAAAAGAAGACTGATGATGATGAAATAACATGGGGAAATGATGAGTTGCCA
ATAGAGAGAACAAACCATGAAGATTCTGATAAAGATCATTCCTTTCTGACAAACGATGAGCTCGCTGTACTCCCTGTCGTCAAAGTGCTT
CCCTCTGGTAAATACACGGGTGCCAACTTAAAATCAGTCATTCGAGTCCTGCGGGGTTTGCTAGATCAAGGAATTCCTTCTAAGGAGCTG
GAGAATCTTCAAGAATTAAAACCTTTGGATCAGTGTCTAATTGGGCAAACTAAGGAAAACAGAAGGAAGAACAGATATAAAAATATACTT
CCCTATGATGCTACAAGAGTGCCTCTTGGAGATGAAGGTGGCTATATCAATGCCAGCTTCATTAAGATACCAGTTGGGAAAGAAGAGTTC
GTTTACATTGCCTGCCAAGGACCACTGCCTACAACTGTTGGAGACTTCTGGCAGATGATTTGGGAGCAAAAATCCACAGTGATAGCCATG
ATGACTCAAGAAGTAGAAGGAGAAAAAATCAAATGCCAGCGCTATTGGCCCAACATCCTAGGCAAAACAACAATGGTCAGCAACAGACTT
CGACTGGCTCTTGTGAGAATGCAGCAGCTGAAGGGCTTTGTGGTGAGGGCAATGACCCTTGAAGATATTCAGACCAGAGAGGTGCGCCAT
ATTTCTCATCTGAATTTCACTGCCTGGCCAGACCATGATACACCTTCTCAACCAGATGATCTGCTTACTTTTATCTCCTACATGAGACAC
ATCCACAGATCAGGCCCAATCATTACGCACTGCAGTGCTGGCATTGGACGTTCAGGGACCCTGATTTGCATAGATGTGGTTCTGGGATTA
ATCAGTCAGGATCTTGATTTTGACATCTCTGATTTGGTGCGCTGCATGAGACTACAAAGACACGGAATGGTTCAGACAGAGGATCAATAT
ATTTTCTGCTATCAAGTCATCCTTTATGTCCTGACACGTCTTCAAGCAGAAGAAGAGCAAAAACAGCAGCCTCAGCTTCTGAAGTGACAT
GAAAAGAGCCTCTGGATGCATTTCCATTTCTCTCCTTAACCTCCAGCAGACTCCTGCTCTCTATCCAAAATAAAGATCACAGAGCAGCAA
GTTCATACAACATGCATGTTCTCCTCTATCTTAGAGGGGTATTCTTCTTGAAAATAAAAAATATTGAAATGCTGTATTTTTACAGCTACT
TTAACCTATGATAATTATTTACAAAATTTTAACACTAACCAAACAATGCAGATCTTAGGGATGATTAAAGGCAGCATTTGATGATAGCAG
ACATTGTTACAAGGACATGGTGAGTCTATTTTTAATGCACCAATCTTGTTTATAGCAAAAATGTTTTCCAATATTTTAATAAAGTAGTTA
TTTTATAGGGGATACTTGAAACCAGTATTTAAGCTTTAAATGACAGTAATATTGGCATAGAAAAAAGTAGCAAATGTTTACTGTATCAAT
TTCTAATGTTTACTATATAGAATTTCCTGTAATATATTTATATACTTTTTCATGAAAATGGAGTTATCAGTTATCTGTTTGTTACTGCAT
CATCTGTTTGTAATCATTATCTCACTTTGTAAATAAAAACACACCTTAAAACATGAACAAGCC

>2666_2666_7_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000307808_PTPN13_chr4_87666119_ENST00000427191_length(amino acids)=2618AA_BP=979
MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP
KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR
ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP
SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEIL
KEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAP
PSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRR
HPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLL
PYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSR
TSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKL
AKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSA
SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAKKMKQKAELMKKKITLQNT
SDGIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRGFNMGRAISTGSLASSTLNKLAVRPLSVQ
AEILKRLSCSELSLYQPLQNSSKEKNDKASWEEKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGV
TKLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVA
PGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYMKKSSYMQDSAIDSSSKD
HHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQVNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKP
GISDVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYV
KAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQ
VKDYSFVTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGT
APEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAP
ANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQPQSESASSSSMDKYHIHH
ISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTH
TDAVNLLRAASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVNGV
STQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTY
QIKGSPNLTLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTEDTDCDGSPLPEYFTEAT
KMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGL
LDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMI
WEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDD
LLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQ
KQQPQLLK

--------------------------------------------------------------
>2666_2666_8_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000307808_PTPN13_chr4_87666119_ENST00000436978_length(transcript)=8969nt_BP=3363nt
GGCAATTTCTTTTCCTTTCTAACTGTGGCCCGCGTTGTGCTGTTGCTGGGCAGGCGTTGGGCGCCGGCGGTCTTCGAGCGTGGGGGCCCG
CTGGCTTTCCCTTCTCAGAAACTGCGCCGGGGGCGCTCGCTTGCCCCGGATTCGGACGCGGCGCTCCCCGGGCTCGTCTGAAGTGCAGAT
CGCCGCAGAGGCCCCAGTGCCCGGATGTCCATCAGGATTAGCGCGAGCCAATACGGGCCGAGCCCGGGGCTGCGCCGAGGACGCCCGGGG
CTCGAGAGCAGGTAGTCCCGTAACATCGGGGCGCCGCGCCGGGACGCGTCCCCGCCCGGCTCCGCCAAATGGTGAGCGCGGCGCTGGCAG
CAGGGCCCGCGGGGTGAAGGCGCTCATGGACGGAAGACCCCTGGCTCTATAAGCTGAATTATGGCAGCCCAGTCAAGTTTGTACAATGAC
GACAGAAACCTGCTTCGAATTAGAGAGAAGGAAAGACGCAACCAGGAAGCCCACCAAGAGAAAGAGGCATTTCCTGAAAAGATTCCCCTT
TTTGGAGAGCCCTACAAGACAGCAAAAGGTGATGAGCTGTCTAGTCGAATACAGAACATGTTGGGAAACTACGAAGAAGTGAAGGAGTTC
CTTAGTACTAAGTCTCACACTCATCGCCTGGATGCTTCTGAAAATAGGTTGGGAAAGCCGAAATATCCTTTAATTCCTGACAAAGGGAGC
AGCATTCCATCCAGCTCCTTCCACACTAGTGTCCACCACCAGTCCATTCACACTCCTGCGTCTGGACCACTTTCTGTTGGCAACATTAGC
CACAATCCAAAGATGGCGCAGCCAAGAACTGAACCAATGCCAAGTCTCCATGCCAAAAGCTGCGGCCCACCGGACAGCCAGCACCTGACC
CAGGATCGCCTTGGTCAGGAGGGGTTCGGCTCTAGTCATCACAAGAAAGGTGACCGAAGAGCTGACGGAGACCACTGTGCTTCGGTGACA
GATTCGGCTCCAGAGAGGGAGCTTTCTCCCTTAATCTCTTTGCCTTCCCCAGTTCCCCCTTTGTCACCTATACATTCCAACCAGCAAACT
CTTCCCCGGACGCAAGGAAGCAGCAAGGTTCATGGCAGCAGCAATAACAGTAAAGGCTATTGCCCAGCCAAATCTCCCAAGGACCTAGCA
GTGAAAGTCCATGATAAAGAGACCCCTCAAGACAGTTTGGTGGCCCCTGCCCAGCCGCCTTCTCAGACATTTCCACCTCCCTCCCTCCCC
TCAAAAAGTGTTGCAATGCAGCAGAAGCCCACGGCTTATGTCCGGCCCATGGATGGTCAAGATCAGGCCCCTAGTGAATCCCCTGAACTG
AAACCACTGCCGGAGGACTATCGACAGCAGACCTTTGAAAAAACAGACTTGAAAGTGCCTGCCAAAGCCAAGCTCACCAAACTGAAGATG
CCTTCTCAGTCAGTTGAGCAGACCTACTCCAATGAAGTCCATTGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCT
TTGACAGCAATACATACGCCTAGTACAGCTGAGCCATCCAAGTTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAA
AACCAAAAACAATATGATACATCTTCAAAAACTCACTCAAATTCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGT
GACAGTGAGGACAGTGACAGTGAACAAACCCCAGAGAAGCCTCCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCA
GTGGCATCAGCACATTCCAGCAGTGCAGAGTCAGAAAGCACCAGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGT
GACAGCGAAGAAAATGAGCCCCTAGAAACCCCAGCTCCGGAGCCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACC
AAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCCCCAGGAGCACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGT
GCCACGAGTCAGGAGCATTCTGAATCCAAAGATCCTCCCCCTAAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCC
GGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGCAGGAGCCCCCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAG
GCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGCAGGGGGAAAGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAA
GACAAGCCCAAGGTGAAGACGAAAGGACGGCCCCGGGCCGCAGCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAG
AAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGGCTCTCTCAGGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCAC
TTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCCCACCCCACAGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTC
CAGGAGGACAGCCGCAAAGACAGACTCCCATTGCCTTTGAGAGACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGC
TTGATGGTGAAGATCACCCTAGACCTGCTCTCTCGGATACCCCAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAG
CCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGAGGAGCTCAGACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGA
GACTGTGATAACAAGAAAATCAGACTGGAGAAGGAAATCAAATCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACA
AAGCCCTCCAGGCCCTCCTCACAGTCCTCAAAGAAGGAAATGCTCCCCCCGCCACCCGTGTCCTCGTCCTCCCAGAAGCCAGCCAAGCCT
GCACTTAAGAGGTCAAGGCGGGAAGCAGACACCTGTGGCCAGGACCCTCCCAAAAGTGCCAGCAGTACCAAGAGCAACCACAAAGACTCT
TCCATTCCCAAGCAGAGAAGAGTAGAGGGGAAGGGCTCCAGAAGCTCCTCGGAGCACAAGGGTTCTTCCGGAGATACTGCAAATCCTTTT
CCAGTGCCTTCTTTGCCAAATGGTAACTCTAAACCAGGGAAGCCTCAAGTGAAGTTTGACAAACAACAAGCAGACCTTCACATGAGGGAG
GCAAAAAAGATGAAGCAGAAAGCAGAGTTAATGAAAAAGAAAATCACATTGCAAAATACATCAGATGGAATAAAACATGGCTTCCAGACA
GACAACAGTAAGATATGCCAGTACCTGCTGCACCTCTGCTCTTACCAGCATAAGTTCCAGCTACAGATGAGAGCAAGACAGAGCAACCAA
GATGCCCAAGATATTGAGAGAGCTTCGTTTAGGAGCCTGAATCTCCAAGCAGAGTCTGTTAGAGGATTTAATATGGGACGAGCAATCAGC
ACTGGCAGTCTGGCCAGCAGCACCCTCAACAAACTTGCTGTTCGACCTTTATCAGTTCAAGCTGAGATTCTGAAGAGGCTATCCTGCTCA
GAGCTGTCGCTTTACCAGCCATTGCAAAACAGTTCAAAAGAGAAGAATGACAAAGCTTCATGGGAGGAAAAGCCTAGAGAGATGAGTAAA
TCATACCATGATCTCAGTCAGGCCTCTCTCTATCCACATCGGAAAAATGTCATTGTTAACATGGAACCCCCACCACAAACCGTTGCAGAG
TTGGTGGGAAAACCTTCTCACCAGATGTCAAGATCTGATGCAGAATCTTTGGCAGGAGTGACAAAACTTAATAATTCAAAGTCTGTTGCG
AGTTTAAATAGAAGTCCTGAAAGGAGGAAACATGAATCAGACTCCTCATCCATTGAAGACCCTGGGCAAGCATATGTTCTAGGAATGACT
ATGCATAGTTCTGGAAACTCTTCATCCCAAGTACCCTTAAAAGAAAATGATGTGCTACACAAAAGATGGAGCATAGTATCTTCACCAGAA
AGGGAGATCACCTTAGTGAACCTGAAAAAAGATGCAAAGTATGGCTTGGGATTTCAAATTATTGGTGGGGAGAAGATGGGAAGACTGGAC
CTAGGCATATTTATCAGTTCAGTTGCCCCTGGAGGACCAGCTGACTTGGATGGATGCTTGAAGCCAGGAGACCGTTTGATATCTGTGAAT
AGTGTGAGTCTGGAGGGAGTCAGCCACCATGCTGCAATTGAAATTTTGCAAAATGCACCTGAAGATGTGACACTTGTTATCTCTCAGCCA
AAAGAAAAGATATCCAAAGTGCCTTCTACTCCTGTGCATCTCACCAATGAGATGAAAAACTACATGAAGAAATCTTCCTACATGCAAGAC
AGTGCTATAGATTCTTCTTCCAAGGATCACCACTGGTCACGTGGTACCCTGAGGCACATCTCGGAGAACTCCTTTGGGCCATCTGGGGGC
CTGCGGGAAGGAAGCCTGAGTTCTCAAGATTCCAGGACTGAGAGTGCCAGCTTGTCTCAAAGCCAGGTCAATGGTTTCTTTGCCAGCCAT
TTAGGTGACCAAACCTGGCAGGAATCACAGCATGGCAGCCCTTCCCCATCTGTAATATCCAAAGCCACCGAGAAAGAGACTTTCACTGAT
AGTAACCAAAGCAAAACTAAAAAGCCAGGCATTTCTGATGTAACTGATTACTCAGACCGTGGAGATTCAGACATGGATGAAGCCACTTAC
TCCAGCAGTCAGGATCATCAAACACCAAAACAGGAATCTTCCTCTTCAGTGAATACATCCAACAAGATGAATTTTAAAACTTTTTCTTCA
TCACCTCCTAAGCCTGGAGATATCTTTGAGGTTGAACTGGCTAAAAATGATAACAGCTTGGGGATAAGTGTCACGGTACTGTTTGACAAG
GGAGGTGTGAATACGAGTGTCAGACATGGTGGCATTTATGTGAAAGCTGTTATTCCCCAGGGAGCAGCAGAGTCTGATGGTAGAATTCAC
AAAGGTGATCGCGTCCTAGCTGTCAATGGAGTTAGTCTAGAAGGAGCCACCCATAAGCAAGCTGTGGAAACACTGAGAAATACAGGACAG
GTGGTTCATCTGTTATTAGAAAAGGGACAATCTCCAACATCTAAAGAACATGTCCCGGTAACCCCACAGTGTACCCTTTCAGATCAGAAT
GCCCAAGGTCAAGGCCCAGAAAAAGTGAAGAAAACAACTCAGGTCAAAGACTACAGCTTTGTCACTGAAGAAAATACATTTGAGGTAAAA
TTATTTAAAAATAGCTCAGGTCTAGGATTCAGTTTTTCTCGAGAAGATAATCTTATACCGGAGCAAATTAATGCCAGCATAGTAAGGGTT
AAAAAGCTCTTTCCTGGACAGCCAGCAGCAGAAAGTGGAAAAATTGATGTAGGAGATGTTATCTTGAAAGTGAATGGAGCCTCTTTGAAA
GGACTATCTCAGCAGGAAGTCATATCTGCTCTCAGGGGAACTGCTCCAGAAGTATTCTTGCTTCTCTGCAGACCTCCACCTGGTGTGCTA
CCGGAAATTGATACTGCGCTTTTGACCCCACTTCAGTCTCCAGCACAAGTACTTCCAAACAGCAGTAAAGACTCTTCTCAGCCATCATGT
GTGGAGCAAAGCACCAGCTCAGATGAAAATGAAATGTCAGACAAAAGCAAAAAACAGTGCAAGTCCCCATCCAGAAGAGACAGTTACAGT
GACAGCAGTGGGAGTGGAGAAGATGACTTAGTGACAGCTCCAGCAAACATATCAAATTCGACCTGGAGTTCAGCTTTGCATCAGACTCTA
AGCAACATGGTATCACAGGCACAGAGTCATCATGAAGCACCCAAGAGTCAAGAAGATACCATTTGTACCATGTTTTACTATCCTCAGAAA
ATTCCCAATAAACCAGAGTTTGAGGACAGTAATCCTTCCCCTCTACCACCGGATATGGCTCCTGGGCAGAGTTATCAACCCCAATCAGAA
TCTGCTTCCTCTAGTTCGATGGATAAGTATCATATACATCACATTTCTGAACCAACTAGACAAGAAAACTGGACACCTTTGAAAAATGAC
TTGGAAAATCACCTTGAAGACTTTGAACTGGAAGTAGAACTCCTCATTACCCTAATTAAATCAGAAAAAGGAAGCCTGGGTTTTACAGTA
ACCAAAGGCAATCAGAGAATTGGTTGTTATGTTCATGATGTCATACAGGATCCAGCCAAAAGTGATGGAAGGCTAAAACCTGGGGACCGG
CTCATAAAGGTTAATGATACAGATGTTACTAATATGACTCATACAGATGCAGTTAATCTGCTCCGGGCTGCATCCAAAACAGTCAGATTA
GTTATTGGACGAGTTCTAGAATTACCCAGAATACCAATGTTGCCTCATTTGCTACCGGACATAACACTAACGTGCAACAAAGAGGAGTTG
GGTTTTTCCTTATGTGGAGGTCATGACAGCCTTTATCAAGTGGTATATATTAGTGATATTAATCCAAGGTCCGTCGCAGCCATTGAGGGT
AATCTCCAGCTATTAGATGTCATCCATTATGTGAACGGAGTCAGCACACAAGGAATGACCTTGGAGGAAGTTAACAGAGCATTAGACATG
TCACTTCCTTCATTGGTATTGAAAGCAACAAGAAATGATCTTCCAGTGGTCCCCAGCTCAAAGAGGTCTGCTGTTTCAGCTCCAAAGTCA
ACCAAAGGCAATGGTTCCTACAGTGTGGGGTCTTGCAGCCAGCCTGCCCTCACTCCTAATGATTCATTCTCCACGGTTGCTGGGGAAGAA
ATAAATGAAATATCGTACCCCAAAGGAAAATGTTCTACTTATCAGATAAAGGGATCACCAAACTTGACTCTGCCCAAAGAATCTTATATA
CAAGAAGATGACATTTATGATGATTCCCAAGAAGCTGAAGTTATCCAGTCTCTGCTGGATGTTGTGGATGAGGAAGCCCAGAATCTTTTA
AACGAAAATAATGCAGCAGGATACTCCTGTGGTCCAGGTACATTAAAGATGAATGGGAAGTTATCAGAAGAGAGAACAGAAGATACAGAC
TGCGATGGTTCACCTTTACCTGAGTATTTTACTGAGGCCACCAAAATGAATGGCTGTGAAGAATATTGTGAAGAAAAAGTAAAAAGTGAA
AGCTTAATTCAGAAGCCACAAGAAAAGAAGACTGATGATGATGAAATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCAT
GAAGATTCTGATAAAGATCATTCCTTTCTGACAAACGATGAGCTCGCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACG
GGTGCCAACTTAAAATCAGTCATTCGAGTCCTGCGGGGTTTGCTAGATCAAGGAATTCCTTCTAAGGAGCTGGAGAATCTTCAAGAATTA
AAACCTTTGGATCAGTGTCTAATTGGGCAAACTAAGGAAAACAGAAGGAAGAACAGATATAAAAATATACTTCCCTATGATGCTACAAGA
GTGCCTCTTGGAGATGAAGGTGGCTATATCAATGCCAGCTTCATTAAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAA
GGACCACTGCCTACAACTGTTGGAGACTTCTGGCAGATGATTTGGGAGCAAAAATCCACAGTGATAGCCATGATGACTCAAGAAGTAGAA
GGAGAAAAAATCAAATGCCAGCGCTATTGGCCCAACATCCTAGGCAAAACAACAATGGTCAGCAACAGACTTCGACTGGCTCTTGTGAGA
ATGCAGCAGCTGAAGGGCTTTGTGGTGAGGGCAATGACCCTTGAAGATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTC
ACTGCCTGGCCAGACCATGATACACCTTCTCAACCAGATGATCTGCTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCA
ATCATTACGCACTGCAGTGCTGGCATTGGACGTTCAGGGACCCTGATTTGCATAGATGTGGTTCTGGGATTAATCAGTCAGGATCTTGAT
TTTGACATCTCTGATTTGGTGCGCTGCATGAGACTACAAAGACACGGAATGGTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTC
ATCCTTTATGTCCTGACACGTCTTCAAGCAGAAGAAGAGCAAAAACAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATG
CATTTCCATTTCTCTCCTTAACCTCCAGCAGACTCCTGCTCTCTATCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGCATG
TTCTCCTCTATCTTAGAGGGGTATTCTTCTTGAAAATAAAAAATATTGAAATGCTGTATTTTTACAGCTACTTTAACCTATGATAATTAT
TTACAAAATTTTAACACTAACCAAACAATGCAGATCTTAGGGATGATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACAT
GGTGAGTCTATTTTTAATGCACCAATCTTGTTTATAGCAAAAATGTTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTG
AAACCAGTATTTAAGCTTTAAATGACAGTAATATTGGCATAGAAAAAAGTAGCAAATGTTTACTGTATCAATTTCTAATGTTTACTATAT
AGAATTTCCTGTAATATATTTATATACTTTTTCATGAAAATGGAGTTATCAGTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATT
ATCTCACTTTGTAAATAAAAACACACCTTAAAACATGAACAAGCCAAAACTGTGTGCAG

>2666_2666_8_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000307808_PTPN13_chr4_87666119_ENST00000436978_length(amino acids)=2642AA_BP=979
MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP
KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR
ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP
SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEIL
KEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAP
PSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRR
HPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLL
PYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSR
TSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKL
AKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSA
SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAKKMKQKAELMKKKITLQNT
SDGIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRGFNMGRAISTGSLASSTLNKLAVRPLSVQ
AEILKRLSCSELSLYQPLQNSSKEKNDKASWEEKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGV
TKLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQI
IGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKN
YMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQVNGFFASHLGDQTWQESQHGSPSPSVIS
KATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSL
GISVTVLFDKGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSPTSKEHVPV
TPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDV
ILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQC
KSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMA
PGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAK
SDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDI
NPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSAPKSTKGNGSYSVGSCSQPALTPN
DSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGK
LSEERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFLTNDELAVLPV
VKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVG
KEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTR
EVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQT
EDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK

--------------------------------------------------------------
>2666_2666_9_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000307808_PTPN13_chr4_87718027_ENST00000427191_length(transcript)=5082nt_BP=3363nt
GGCAATTTCTTTTCCTTTCTAACTGTGGCCCGCGTTGTGCTGTTGCTGGGCAGGCGTTGGGCGCCGGCGGTCTTCGAGCGTGGGGGCCCG
CTGGCTTTCCCTTCTCAGAAACTGCGCCGGGGGCGCTCGCTTGCCCCGGATTCGGACGCGGCGCTCCCCGGGCTCGTCTGAAGTGCAGAT
CGCCGCAGAGGCCCCAGTGCCCGGATGTCCATCAGGATTAGCGCGAGCCAATACGGGCCGAGCCCGGGGCTGCGCCGAGGACGCCCGGGG
CTCGAGAGCAGGTAGTCCCGTAACATCGGGGCGCCGCGCCGGGACGCGTCCCCGCCCGGCTCCGCCAAATGGTGAGCGCGGCGCTGGCAG
CAGGGCCCGCGGGGTGAAGGCGCTCATGGACGGAAGACCCCTGGCTCTATAAGCTGAATTATGGCAGCCCAGTCAAGTTTGTACAATGAC
GACAGAAACCTGCTTCGAATTAGAGAGAAGGAAAGACGCAACCAGGAAGCCCACCAAGAGAAAGAGGCATTTCCTGAAAAGATTCCCCTT
TTTGGAGAGCCCTACAAGACAGCAAAAGGTGATGAGCTGTCTAGTCGAATACAGAACATGTTGGGAAACTACGAAGAAGTGAAGGAGTTC
CTTAGTACTAAGTCTCACACTCATCGCCTGGATGCTTCTGAAAATAGGTTGGGAAAGCCGAAATATCCTTTAATTCCTGACAAAGGGAGC
AGCATTCCATCCAGCTCCTTCCACACTAGTGTCCACCACCAGTCCATTCACACTCCTGCGTCTGGACCACTTTCTGTTGGCAACATTAGC
CACAATCCAAAGATGGCGCAGCCAAGAACTGAACCAATGCCAAGTCTCCATGCCAAAAGCTGCGGCCCACCGGACAGCCAGCACCTGACC
CAGGATCGCCTTGGTCAGGAGGGGTTCGGCTCTAGTCATCACAAGAAAGGTGACCGAAGAGCTGACGGAGACCACTGTGCTTCGGTGACA
GATTCGGCTCCAGAGAGGGAGCTTTCTCCCTTAATCTCTTTGCCTTCCCCAGTTCCCCCTTTGTCACCTATACATTCCAACCAGCAAACT
CTTCCCCGGACGCAAGGAAGCAGCAAGGTTCATGGCAGCAGCAATAACAGTAAAGGCTATTGCCCAGCCAAATCTCCCAAGGACCTAGCA
GTGAAAGTCCATGATAAAGAGACCCCTCAAGACAGTTTGGTGGCCCCTGCCCAGCCGCCTTCTCAGACATTTCCACCTCCCTCCCTCCCC
TCAAAAAGTGTTGCAATGCAGCAGAAGCCCACGGCTTATGTCCGGCCCATGGATGGTCAAGATCAGGCCCCTAGTGAATCCCCTGAACTG
AAACCACTGCCGGAGGACTATCGACAGCAGACCTTTGAAAAAACAGACTTGAAAGTGCCTGCCAAAGCCAAGCTCACCAAACTGAAGATG
CCTTCTCAGTCAGTTGAGCAGACCTACTCCAATGAAGTCCATTGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCT
TTGACAGCAATACATACGCCTAGTACAGCTGAGCCATCCAAGTTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAA
AACCAAAAACAATATGATACATCTTCAAAAACTCACTCAAATTCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGT
GACAGTGAGGACAGTGACAGTGAACAAACCCCAGAGAAGCCTCCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCA
GTGGCATCAGCACATTCCAGCAGTGCAGAGTCAGAAAGCACCAGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGT
GACAGCGAAGAAAATGAGCCCCTAGAAACCCCAGCTCCGGAGCCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACC
AAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCCCCAGGAGCACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGT
GCCACGAGTCAGGAGCATTCTGAATCCAAAGATCCTCCCCCTAAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCC
GGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGCAGGAGCCCCCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAG
GCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGCAGGGGGAAAGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAA
GACAAGCCCAAGGTGAAGACGAAAGGACGGCCCCGGGCCGCAGCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAG
AAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGGCTCTCTCAGGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCAC
TTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCCCACCCCACAGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTC
CAGGAGGACAGCCGCAAAGACAGACTCCCATTGCCTTTGAGAGACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGC
TTGATGGTGAAGATCACCCTAGACCTGCTCTCTCGGATACCCCAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAG
CCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGAGGAGCTCAGACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGA
GACTGTGATAACAAGAAAATCAGACTGGAGAAGGAAATCAAATCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACA
AAGCCCTCCAGGCCCTCCTCACAGTCCTCAAAGAAGGAAATGCTCCCCCCGCCACCCGTGTCCTCGTCCTCCCAGAAGCCAGCCAAGCCT
GCACTTAAGAGGTCAAGGCGGGAAGCAGACACCTGTGGCCAGGACCCTCCCAAAAGTGCCAGCAGTACCAAGAGCAACCACAAAGACTCT
TCCATTCCCAAGCAGAGAAGAGTAGAGGGGAAGGGCTCCAGAAGCTCCTCGGAGCACAAGGGTTCTTCCGGAGATACTGCAAATCCTTTT
CCAGTGCCTTCTTTGCCAAATGGTAACTCTAAACCAGGGAAGCCTCAAGTGAAGTTTGACAAACAACAAGCAGACCTTCACATGAGGGAG
GCAAAAAAGATGAAGCAGAAAGCAGAGTTAATGGCCACCAAAATGAATGGCTGTGAAGAATATTGTGAAGAAAAAGTAAAAAGTGAAAGC
TTAATTCAGAAGCCACAAGAAAAGAAGACTGATGATGATGAAATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCATGAA
GATTCTGATAAAGATCATTCCTTTCTGACAAACGATGAGCTCGCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACGGGT
GCCAACTTAAAATCAGTCATTCGAGTCCTGCGGGGTTTGCTAGATCAAGGAATTCCTTCTAAGGAGCTGGAGAATCTTCAAGAATTAAAA
CCTTTGGATCAGTGTCTAATTGGGCAAACTAAGGAAAACAGAAGGAAGAACAGATATAAAAATATACTTCCCTATGATGCTACAAGAGTG
CCTCTTGGAGATGAAGGTGGCTATATCAATGCCAGCTTCATTAAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAAGGA
CCACTGCCTACAACTGTTGGAGACTTCTGGCAGATGATTTGGGAGCAAAAATCCACAGTGATAGCCATGATGACTCAAGAAGTAGAAGGA
GAAAAAATCAAATGCCAGCGCTATTGGCCCAACATCCTAGGCAAAACAACAATGGTCAGCAACAGACTTCGACTGGCTCTTGTGAGAATG
CAGCAGCTGAAGGGCTTTGTGGTGAGGGCAATGACCCTTGAAGATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTCACT
GCCTGGCCAGACCATGATACACCTTCTCAACCAGATGATCTGCTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCAATC
ATTACGCACTGCAGTGCTGGCATTGGACGTTCAGGGACCCTGATTTGCATAGATGTGGTTCTGGGATTAATCAGTCAGGATCTTGATTTT
GACATCTCTGATTTGGTGCGCTGCATGAGACTACAAAGACACGGAATGGTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTCATC
CTTTATGTCCTGACACGTCTTCAAGCAGAAGAAGAGCAAAAACAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATGCAT
TTCCATTTCTCTCCTTAACCTCCAGCAGACTCCTGCTCTCTATCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGCATGTTC
TCCTCTATCTTAGAGGGGTATTCTTCTTGAAAATAAAAAATATTGAAATGCTGTATTTTTACAGCTACTTTAACCTATGATAATTATTTA
CAAAATTTTAACACTAACCAAACAATGCAGATCTTAGGGATGATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACATGGT
GAGTCTATTTTTAATGCACCAATCTTGTTTATAGCAAAAATGTTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTGAAA
CCAGTATTTAAGCTTTAAATGACAGTAATATTGGCATAGAAAAAAGTAGCAAATGTTTACTGTATCAATTTCTAATGTTTACTATATAGA
ATTTCCTGTAATATATTTATATACTTTTTCATGAAAATGGAGTTATCAGTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATTATC
TCACTTTGTAAATAAAAACACACCTTAAAACATGAACAAGCC

>2666_2666_9_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000307808_PTPN13_chr4_87718027_ENST00000427191_length(amino acids)=1351AA_BP=979
MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP
KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR
ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP
SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEIL
KEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAP
PSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRR
HPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLL
PYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSR
TSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKL
AKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSA
SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAKKMKQKAELMATKMNGCEE
YCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPS
KELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTV
IAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISY
MRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQKQQPQLL
K

--------------------------------------------------------------
>2666_2666_10_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000307808_PTPN13_chr4_87718027_ENST00000436978_length(transcript)=5096nt_BP=3363nt
GGCAATTTCTTTTCCTTTCTAACTGTGGCCCGCGTTGTGCTGTTGCTGGGCAGGCGTTGGGCGCCGGCGGTCTTCGAGCGTGGGGGCCCG
CTGGCTTTCCCTTCTCAGAAACTGCGCCGGGGGCGCTCGCTTGCCCCGGATTCGGACGCGGCGCTCCCCGGGCTCGTCTGAAGTGCAGAT
CGCCGCAGAGGCCCCAGTGCCCGGATGTCCATCAGGATTAGCGCGAGCCAATACGGGCCGAGCCCGGGGCTGCGCCGAGGACGCCCGGGG
CTCGAGAGCAGGTAGTCCCGTAACATCGGGGCGCCGCGCCGGGACGCGTCCCCGCCCGGCTCCGCCAAATGGTGAGCGCGGCGCTGGCAG
CAGGGCCCGCGGGGTGAAGGCGCTCATGGACGGAAGACCCCTGGCTCTATAAGCTGAATTATGGCAGCCCAGTCAAGTTTGTACAATGAC
GACAGAAACCTGCTTCGAATTAGAGAGAAGGAAAGACGCAACCAGGAAGCCCACCAAGAGAAAGAGGCATTTCCTGAAAAGATTCCCCTT
TTTGGAGAGCCCTACAAGACAGCAAAAGGTGATGAGCTGTCTAGTCGAATACAGAACATGTTGGGAAACTACGAAGAAGTGAAGGAGTTC
CTTAGTACTAAGTCTCACACTCATCGCCTGGATGCTTCTGAAAATAGGTTGGGAAAGCCGAAATATCCTTTAATTCCTGACAAAGGGAGC
AGCATTCCATCCAGCTCCTTCCACACTAGTGTCCACCACCAGTCCATTCACACTCCTGCGTCTGGACCACTTTCTGTTGGCAACATTAGC
CACAATCCAAAGATGGCGCAGCCAAGAACTGAACCAATGCCAAGTCTCCATGCCAAAAGCTGCGGCCCACCGGACAGCCAGCACCTGACC
CAGGATCGCCTTGGTCAGGAGGGGTTCGGCTCTAGTCATCACAAGAAAGGTGACCGAAGAGCTGACGGAGACCACTGTGCTTCGGTGACA
GATTCGGCTCCAGAGAGGGAGCTTTCTCCCTTAATCTCTTTGCCTTCCCCAGTTCCCCCTTTGTCACCTATACATTCCAACCAGCAAACT
CTTCCCCGGACGCAAGGAAGCAGCAAGGTTCATGGCAGCAGCAATAACAGTAAAGGCTATTGCCCAGCCAAATCTCCCAAGGACCTAGCA
GTGAAAGTCCATGATAAAGAGACCCCTCAAGACAGTTTGGTGGCCCCTGCCCAGCCGCCTTCTCAGACATTTCCACCTCCCTCCCTCCCC
TCAAAAAGTGTTGCAATGCAGCAGAAGCCCACGGCTTATGTCCGGCCCATGGATGGTCAAGATCAGGCCCCTAGTGAATCCCCTGAACTG
AAACCACTGCCGGAGGACTATCGACAGCAGACCTTTGAAAAAACAGACTTGAAAGTGCCTGCCAAAGCCAAGCTCACCAAACTGAAGATG
CCTTCTCAGTCAGTTGAGCAGACCTACTCCAATGAAGTCCATTGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCT
TTGACAGCAATACATACGCCTAGTACAGCTGAGCCATCCAAGTTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAA
AACCAAAAACAATATGATACATCTTCAAAAACTCACTCAAATTCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGT
GACAGTGAGGACAGTGACAGTGAACAAACCCCAGAGAAGCCTCCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCA
GTGGCATCAGCACATTCCAGCAGTGCAGAGTCAGAAAGCACCAGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGT
GACAGCGAAGAAAATGAGCCCCTAGAAACCCCAGCTCCGGAGCCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACC
AAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCCCCAGGAGCACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGT
GCCACGAGTCAGGAGCATTCTGAATCCAAAGATCCTCCCCCTAAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCC
GGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGCAGGAGCCCCCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAG
GCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGCAGGGGGAAAGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAA
GACAAGCCCAAGGTGAAGACGAAAGGACGGCCCCGGGCCGCAGCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAG
AAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGGCTCTCTCAGGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCAC
TTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCCCACCCCACAGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTC
CAGGAGGACAGCCGCAAAGACAGACTCCCATTGCCTTTGAGAGACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGC
TTGATGGTGAAGATCACCCTAGACCTGCTCTCTCGGATACCCCAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAG
CCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGAGGAGCTCAGACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGA
GACTGTGATAACAAGAAAATCAGACTGGAGAAGGAAATCAAATCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACA
AAGCCCTCCAGGCCCTCCTCACAGTCCTCAAAGAAGGAAATGCTCCCCCCGCCACCCGTGTCCTCGTCCTCCCAGAAGCCAGCCAAGCCT
GCACTTAAGAGGTCAAGGCGGGAAGCAGACACCTGTGGCCAGGACCCTCCCAAAAGTGCCAGCAGTACCAAGAGCAACCACAAAGACTCT
TCCATTCCCAAGCAGAGAAGAGTAGAGGGGAAGGGCTCCAGAAGCTCCTCGGAGCACAAGGGTTCTTCCGGAGATACTGCAAATCCTTTT
CCAGTGCCTTCTTTGCCAAATGGTAACTCTAAACCAGGGAAGCCTCAAGTGAAGTTTGACAAACAACAAGCAGACCTTCACATGAGGGAG
GCAAAAAAGATGAAGCAGAAAGCAGAGTTAATGGCCACCAAAATGAATGGCTGTGAAGAATATTGTGAAGAAAAAGTAAAAAGTGAAAGC
TTAATTCAGAAGCCACAAGAAAAGAAGACTGATGATGATGAAATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCATGAA
GATTCTGATAAAGATCATTCCTTTCTGACAAACGATGAGCTCGCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACGGGT
GCCAACTTAAAATCAGTCATTCGAGTCCTGCGGGGTTTGCTAGATCAAGGAATTCCTTCTAAGGAGCTGGAGAATCTTCAAGAATTAAAA
CCTTTGGATCAGTGTCTAATTGGGCAAACTAAGGAAAACAGAAGGAAGAACAGATATAAAAATATACTTCCCTATGATGCTACAAGAGTG
CCTCTTGGAGATGAAGGTGGCTATATCAATGCCAGCTTCATTAAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAAGGA
CCACTGCCTACAACTGTTGGAGACTTCTGGCAGATGATTTGGGAGCAAAAATCCACAGTGATAGCCATGATGACTCAAGAAGTAGAAGGA
GAAAAAATCAAATGCCAGCGCTATTGGCCCAACATCCTAGGCAAAACAACAATGGTCAGCAACAGACTTCGACTGGCTCTTGTGAGAATG
CAGCAGCTGAAGGGCTTTGTGGTGAGGGCAATGACCCTTGAAGATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTCACT
GCCTGGCCAGACCATGATACACCTTCTCAACCAGATGATCTGCTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCAATC
ATTACGCACTGCAGTGCTGGCATTGGACGTTCAGGGACCCTGATTTGCATAGATGTGGTTCTGGGATTAATCAGTCAGGATCTTGATTTT
GACATCTCTGATTTGGTGCGCTGCATGAGACTACAAAGACACGGAATGGTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTCATC
CTTTATGTCCTGACACGTCTTCAAGCAGAAGAAGAGCAAAAACAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATGCAT
TTCCATTTCTCTCCTTAACCTCCAGCAGACTCCTGCTCTCTATCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGCATGTTC
TCCTCTATCTTAGAGGGGTATTCTTCTTGAAAATAAAAAATATTGAAATGCTGTATTTTTACAGCTACTTTAACCTATGATAATTATTTA
CAAAATTTTAACACTAACCAAACAATGCAGATCTTAGGGATGATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACATGGT
GAGTCTATTTTTAATGCACCAATCTTGTTTATAGCAAAAATGTTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTGAAA
CCAGTATTTAAGCTTTAAATGACAGTAATATTGGCATAGAAAAAAGTAGCAAATGTTTACTGTATCAATTTCTAATGTTTACTATATAGA
ATTTCCTGTAATATATTTATATACTTTTTCATGAAAATGGAGTTATCAGTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATTATC
TCACTTTGTAAATAAAAACACACCTTAAAACATGAACAAGCCAAAACTGTGTGCAG

>2666_2666_10_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000307808_PTPN13_chr4_87718027_ENST00000436978_length(amino acids)=1351AA_BP=979
MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP
KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR
ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP
SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEIL
KEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAP
PSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRR
HPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLL
PYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSR
TSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKL
AKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSA
SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAKKMKQKAELMATKMNGCEE
YCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPS
KELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTV
IAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISY
MRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQKQQPQLL
K

--------------------------------------------------------------
>2666_2666_11_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000395146_PTPN13_chr4_87666119_ENST00000427191_length(transcript)=8759nt_BP=3239nt
GAGCTTGCCAGCCAGCTAGCGAGCGACGGGCGCGCGCGGCCCCTGCGCACTCGGCCGCCGCCTGCGCGCGTTGCGGCCGCAGCTGCACCT
TTGCCTCCGCGGTTCCGCAGCCGAGCCCCGGGAGGAGGCGCTCCCCTGCGTCGTCCGCACTTGCGCCCTTTCCCACCGCAACAGGTCAGG
GGAGGGCGGAGGTGACGAGGGCGCCCGACCCGGGACTAGAGGACGGAAGGGTCTGGAAGATGAACAGACTAGCCACTTTGCATTGACTGG
AAACAATGGCATTTACAGAAAGAGTCAACAGCAGTGGCAACAGTTTGTACAATGACGACAGAAACCTGCTTCGAATTAGAGAGAAGGAAA
GACGCAACCAGGAAGCCCACCAAGAGAAAGAGGCATTTCCTGAAAAGATTCCCCTTTTTGGAGAGCCCTACAAGACAGCAAAAGGTGATG
AGCTGTCTAGTCGAATACAGAACATGTTGGGAAACTACGAAGAAGTGAAGGAGTTCCTTAGTACTAAGTCTCACACTCATCGCCTGGATG
CTTCTGAAAATAGGTTGGGAAAGCCGAAATATCCTTTAATTCCTGACAAAGGGAGCAGCATTCCATCCAGCTCCTTCCACACTAGTGTCC
ACCACCAGTCCATTCACACTCCTGCGTCTGGACCACTTTCTGTTGGCAACATTAGCCACAATCCAAAGATGGCGCAGCCAAGAACTGAAC
CAATGCCAAGTCTCCATGCCAAAAGCTGCGGCCCACCGGACAGCCAGCACCTGACCCAGGATCGCCTTGGTCAGGAGGGGTTCGGCTCTA
GTCATCACAAGAAAGGTGACCGAAGAGCTGACGGAGACCACTGTGCTTCGGTGACAGATTCGGCTCCAGAGAGGGAGCTTTCTCCCTTAA
TCTCTTTGCCTTCCCCAGTTCCCCCTTTGTCACCTATACATTCCAACCAGCAAACTCTTCCCCGGACGCAAGGAAGCAGCAAGGTTCATG
GCAGCAGCAATAACAGTAAAGGCTATTGCCCAGCCAAATCTCCCAAGGACCTAGCAGTGAAAGTCCATGATAAAGAGACCCCTCAAGACA
GTTTGGTGGCCCCTGCCCAGCCGCCTTCTCAGACATTTCCACCTCCCTCCCTCCCCTCAAAAAGTGTTGCAATGCAGCAGAAGCCCACGG
CTTATGTCCGGCCCATGGATGGTCAAGATCAGGCCCCTAGTGAATCCCCTGAACTGAAACCACTGCCGGAGGACTATCGACAGCAGACCT
TTGAAAAAACAGACTTGAAAGTGCCTGCCAAAGCCAAGCTCACCAAACTGAAGATGCCTTCTCAGTCAGTTGAGCAGACCTACTCCAATG
AAGTCCATTGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCTTTGACAGCAATACATACGCCTAGTACAGCTGAGC
CATCCAAGTTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAAAACCAAAAACAATATGATACATCTTCAAAAACTC
ACTCAAATTCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGTGACAGTGAGGACAGTGACAGTGAACAAACCCCAG
AGAAGCCTCCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCAGTGGCATCAGCACATTCCAGCAGTGCAGAGTCAG
AAAGCACCAGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGTGACAGCGAAGAAAATGAGCCCCTAGAAACCCCAG
CTCCGGAGCCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACCAAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCC
CCAGGAGCACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGTGCCACGAGTCAGGAGCATTCTGAATCCAAAGATC
CTCCCCCTAAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCCGGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGC
AGGAGCCCCCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAGGCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGC
AGGGGGAAAGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAAGACAAGCCCAAGGTGAAGACGAAAGGACGGCCCC
GGGCCGCAGCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAGAAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGG
CTCTCTCAGGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCACTTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCC
CACCCCACAGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTCCAGGAGGACAGCCGCAAAGACAGACTCCCATTGC
CTTTGAGAGACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGCTTGATGGTGAAGATCACCCTAGACCTGCTCTCTC
GGATACCCCAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAGCCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGA
GGAGCTCAGACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGAGACTGTGATAACAAGAAAATCAGACTGGAGAAGG
AAATCAAATCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACAAAGCCCTCCAGGCCCTCCTCACAGTCCTCAAAGA
AGGAAATGCTCCCCCCGCCACCCGTGTCCTCGTCCTCCCAGAAGCCAGCCAAGCCTGCACTTAAGAGGTCAAGGCGGGAAGCAGACACCT
GTGGCCAGGACCCTCCCAAAAGTGCCAGCAGTACCAAGAGCAACCACAAAGACTCTTCCATTCCCAAGCAGAGAAGAGTAGAGGGGAAGG
GCTCCAGAAGCTCCTCGGAGCACAAGGGTTCTTCCGGAGATACTGCAAATCCTTTTCCAGTGCCTTCTTTGCCAAATGGTAACTCTAAAC
CAGGGAAGCCTCAAGTGAAGTTTGACAAACAACAAGCAGACCTTCACATGAGGGAGGCAAAAAAGATGAAGCAGAAAGCAGAGTTAATGA
AAAAGAAAATCACATTGCAAAATACATCAGATGGAATAAAACATGGCTTCCAGACAGACAACAGTAAGATATGCCAGTACCTGCTGCACC
TCTGCTCTTACCAGCATAAGTTCCAGCTACAGATGAGAGCAAGACAGAGCAACCAAGATGCCCAAGATATTGAGAGAGCTTCGTTTAGGA
GCCTGAATCTCCAAGCAGAGTCTGTTAGAGGATTTAATATGGGACGAGCAATCAGCACTGGCAGTCTGGCCAGCAGCACCCTCAACAAAC
TTGCTGTTCGACCTTTATCAGTTCAAGCTGAGATTCTGAAGAGGCTATCCTGCTCAGAGCTGTCGCTTTACCAGCCATTGCAAAACAGTT
CAAAAGAGAAGAATGACAAAGCTTCATGGGAGGAAAAGCCTAGAGAGATGAGTAAATCATACCATGATCTCAGTCAGGCCTCTCTCTATC
CACATCGGAAAAATGTCATTGTTAACATGGAACCCCCACCACAAACCGTTGCAGAGTTGGTGGGAAAACCTTCTCACCAGATGTCAAGAT
CTGATGCAGAATCTTTGGCAGGAGTGACAAAACTTAATAATTCAAAGTCTGTTGCGAGTTTAAATAGAAGTCCTGAAAGGAGGAAACATG
AATCAGACTCCTCATCCATTGAAGACCCTGGGCAAGCATATGTTCTAGATGTGCTACACAAAAGATGGAGCATAGTATCTTCACCAGAAA
GGGAGATCACCTTAGTGAACCTGAAAAAAGATGCAAAGTATGGCTTGGGATTTCAAATTATTGGTGGGGAGAAGATGGGAAGACTGGACC
TAGGCATATTTATCAGTTCAGTTGCCCCTGGAGGACCAGCTGACTTGGATGGATGCTTGAAGCCAGGAGACCGTTTGATATCTGTGAATA
GTGTGAGTCTGGAGGGAGTCAGCCACCATGCTGCAATTGAAATTTTGCAAAATGCACCTGAAGATGTGACACTTGTTATCTCTCAGCCAA
AAGAAAAGATATCCAAAGTGCCTTCTACTCCTGTGCATCTCACCAATGAGATGAAAAACTACATGAAGAAATCTTCCTACATGCAAGACA
GTGCTATAGATTCTTCTTCCAAGGATCACCACTGGTCACGTGGTACCCTGAGGCACATCTCGGAGAACTCCTTTGGGCCATCTGGGGGCC
TGCGGGAAGGAAGCCTGAGTTCTCAAGATTCCAGGACTGAGAGTGCCAGCTTGTCTCAAAGCCAGGTCAATGGTTTCTTTGCCAGCCATT
TAGGTGACCAAACCTGGCAGGAATCACAGCATGGCAGCCCTTCCCCATCTGTAATATCCAAAGCCACCGAGAAAGAGACTTTCACTGATA
GTAACCAAAGCAAAACTAAAAAGCCAGGCATTTCTGATGTAACTGATTACTCAGACCGTGGAGATTCAGACATGGATGAAGCCACTTACT
CCAGCAGTCAGGATCATCAAACACCAAAACAGGAATCTTCCTCTTCAGTGAATACATCCAACAAGATGAATTTTAAAACTTTTTCTTCAT
CACCTCCTAAGCCTGGAGATATCTTTGAGGTTGAACTGGCTAAAAATGATAACAGCTTGGGGATAAGTGTCACGGGAGGTGTGAATACGA
GTGTCAGACATGGTGGCATTTATGTGAAAGCTGTTATTCCCCAGGGAGCAGCAGAGTCTGATGGTAGAATTCACAAAGGTGATCGCGTCC
TAGCTGTCAATGGAGTTAGTCTAGAAGGAGCCACCCATAAGCAAGCTGTGGAAACACTGAGAAATACAGGACAGGTGGTTCATCTGTTAT
TAGAAAAGGGACAATCTCCAACATCTAAAGAACATGTCCCGGTAACCCCACAGTGTACCCTTTCAGATCAGAATGCCCAAGGTCAAGGCC
CAGAAAAAGTGAAGAAAACAACTCAGGTCAAAGACTACAGCTTTGTCACTGAAGAAAATACATTTGAGGTAAAATTATTTAAAAATAGCT
CAGGTCTAGGATTCAGTTTTTCTCGAGAAGATAATCTTATACCGGAGCAAATTAATGCCAGCATAGTAAGGGTTAAAAAGCTCTTTCCTG
GACAGCCAGCAGCAGAAAGTGGAAAAATTGATGTAGGAGATGTTATCTTGAAAGTGAATGGAGCCTCTTTGAAAGGACTATCTCAGCAGG
AAGTCATATCTGCTCTCAGGGGAACTGCTCCAGAAGTATTCTTGCTTCTCTGCAGACCTCCACCTGGTGTGCTACCGGAAATTGATACTG
CGCTTTTGACCCCACTTCAGTCTCCAGCACAAGTACTTCCAAACAGCAGTAAAGACTCTTCTCAGCCATCATGTGTGGAGCAAAGCACCA
GCTCAGATGAAAATGAAATGTCAGACAAAAGCAAAAAACAGTGCAAGTCCCCATCCAGAAGAGACAGTTACAGTGACAGCAGTGGGAGTG
GAGAAGATGACTTAGTGACAGCTCCAGCAAACATATCAAATTCGACCTGGAGTTCAGCTTTGCATCAGACTCTAAGCAACATGGTATCAC
AGGCACAGAGTCATCATGAAGCACCCAAGAGTCAAGAAGATACCATTTGTACCATGTTTTACTATCCTCAGAAAATTCCCAATAAACCAG
AGTTTGAGGACAGTAATCCTTCCCCTCTACCACCGGATATGGCTCCTGGGCAGAGTTATCAACCCCAATCAGAATCTGCTTCCTCTAGTT
CGATGGATAAGTATCATATACATCACATTTCTGAACCAACTAGACAAGAAAACTGGACACCTTTGAAAAATGACTTGGAAAATCACCTTG
AAGACTTTGAACTGGAAGTAGAACTCCTCATTACCCTAATTAAATCAGAAAAAGGAAGCCTGGGTTTTACAGTAACCAAAGGCAATCAGA
GAATTGGTTGTTATGTTCATGATGTCATACAGGATCCAGCCAAAAGTGATGGAAGGCTAAAACCTGGGGACCGGCTCATAAAGGTTAATG
ATACAGATGTTACTAATATGACTCATACAGATGCAGTTAATCTGCTCCGGGCTGCATCCAAAACAGTCAGATTAGTTATTGGACGAGTTC
TAGAATTACCCAGAATACCAATGTTGCCTCATTTGCTACCGGACATAACACTAACGTGCAACAAAGAGGAGTTGGGTTTTTCCTTATGTG
GAGGTCATGACAGCCTTTATCAAGTGGTATATATTAGTGATATTAATCCAAGGTCCGTCGCAGCCATTGAGGGTAATCTCCAGCTATTAG
ATGTCATCCATTATGTGAACGGAGTCAGCACACAAGGAATGACCTTGGAGGAAGTTAACAGAGCATTAGACATGTCACTTCCTTCATTGG
TATTGAAAGCAACAAGAAATGATCTTCCAGTGGTCCCCAGCTCAAAGAGGTCTGCTGTTTCAGCTCCAAAGTCAACCAAAGGCAATGGTT
CCTACAGTGTGGGGTCTTGCAGCCAGCCTGCCCTCACTCCTAATGATTCATTCTCCACGGTTGCTGGGGAAGAAATAAATGAAATATCGT
ACCCCAAAGGAAAATGTTCTACTTATCAGATAAAGGGATCACCAAACTTGACTCTGCCCAAAGAATCTTATATACAAGAAGATGACATTT
ATGATGATTCCCAAGAAGCTGAAGTTATCCAGTCTCTGCTGGATGTTGTGGATGAGGAAGCCCAGAATCTTTTAAACGAAAATAATGCAG
CAGGATACTCCTGTGGTCCAGGTACATTAAAGATGAATGGGAAGTTATCAGAAGAGAGAACAGAAGATACAGACTGCGATGGTTCACCTT
TACCTGAGTATTTTACTGAGGCCACCAAAATGAATGGCTGTGAAGAATATTGTGAAGAAAAAGTAAAAAGTGAAAGCTTAATTCAGAAGC
CACAAGAAAAGAAGACTGATGATGATGAAATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCATGAAGATTCTGATAAAG
ATCATTCCTTTCTGACAAACGATGAGCTCGCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACGGGTGCCAACTTAAAAT
CAGTCATTCGAGTCCTGCGGGGTTTGCTAGATCAAGGAATTCCTTCTAAGGAGCTGGAGAATCTTCAAGAATTAAAACCTTTGGATCAGT
GTCTAATTGGGCAAACTAAGGAAAACAGAAGGAAGAACAGATATAAAAATATACTTCCCTATGATGCTACAAGAGTGCCTCTTGGAGATG
AAGGTGGCTATATCAATGCCAGCTTCATTAAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAAGGACCACTGCCTACAA
CTGTTGGAGACTTCTGGCAGATGATTTGGGAGCAAAAATCCACAGTGATAGCCATGATGACTCAAGAAGTAGAAGGAGAAAAAATCAAAT
GCCAGCGCTATTGGCCCAACATCCTAGGCAAAACAACAATGGTCAGCAACAGACTTCGACTGGCTCTTGTGAGAATGCAGCAGCTGAAGG
GCTTTGTGGTGAGGGCAATGACCCTTGAAGATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTCACTGCCTGGCCAGACC
ATGATACACCTTCTCAACCAGATGATCTGCTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCAATCATTACGCACTGCA
GTGCTGGCATTGGACGTTCAGGGACCCTGATTTGCATAGATGTGGTTCTGGGATTAATCAGTCAGGATCTTGATTTTGACATCTCTGATT
TGGTGCGCTGCATGAGACTACAAAGACACGGAATGGTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTCATCCTTTATGTCCTGA
CACGTCTTCAAGCAGAAGAAGAGCAAAAACAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATGCATTTCCATTTCTCTC
CTTAACCTCCAGCAGACTCCTGCTCTCTATCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGCATGTTCTCCTCTATCTTAG
AGGGGTATTCTTCTTGAAAATAAAAAATATTGAAATGCTGTATTTTTACAGCTACTTTAACCTATGATAATTATTTACAAAATTTTAACA
CTAACCAAACAATGCAGATCTTAGGGATGATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACATGGTGAGTCTATTTTTA
ATGCACCAATCTTGTTTATAGCAAAAATGTTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTGAAACCAGTATTTAAGC
TTTAAATGACAGTAATATTGGCATAGAAAAAAGTAGCAAATGTTTACTGTATCAATTTCTAATGTTTACTATATAGAATTTCCTGTAATA
TATTTATATACTTTTTCATGAAAATGGAGTTATCAGTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATTATCTCACTTTGTAAAT
AAAAACACACCTTAAAACATGAACAAGCC

>2666_2666_11_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000395146_PTPN13_chr4_87666119_ENST00000427191_length(amino acids)=2628AA_BP=989
METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL
DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG
SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ
DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYS
NEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQT
PEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPE
GPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTS
LQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQ
GPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSE
KRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREAD
TCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAKKMKQKAEL
MKKKITLQNTSDGIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRGFNMGRAISTGSLASSTLN
KLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWEEKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMS
RSDAESLAGVTKLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRL
DLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYMKKSSYMQ
DSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQVNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFT
DSNQSKTKKPGISDVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGISVTGGVN
TSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQ
GPEKVKKTTQVKDYSFVTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQ
QEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSG
SGEDDLVTAPANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQPQSESASS
SSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKV
NDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAAIEGNLQL
LDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEI
SYPKGKCSTYQIKGSPNLTLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTEDTDCDGS
PLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANL
KSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLP
TTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWP
DHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV
LTRLQAEEEQKQQPQLLK

--------------------------------------------------------------
>2666_2666_12_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000395146_PTPN13_chr4_87666119_ENST00000436978_length(transcript)=8845nt_BP=3239nt
GAGCTTGCCAGCCAGCTAGCGAGCGACGGGCGCGCGCGGCCCCTGCGCACTCGGCCGCCGCCTGCGCGCGTTGCGGCCGCAGCTGCACCT
TTGCCTCCGCGGTTCCGCAGCCGAGCCCCGGGAGGAGGCGCTCCCCTGCGTCGTCCGCACTTGCGCCCTTTCCCACCGCAACAGGTCAGG
GGAGGGCGGAGGTGACGAGGGCGCCCGACCCGGGACTAGAGGACGGAAGGGTCTGGAAGATGAACAGACTAGCCACTTTGCATTGACTGG
AAACAATGGCATTTACAGAAAGAGTCAACAGCAGTGGCAACAGTTTGTACAATGACGACAGAAACCTGCTTCGAATTAGAGAGAAGGAAA
GACGCAACCAGGAAGCCCACCAAGAGAAAGAGGCATTTCCTGAAAAGATTCCCCTTTTTGGAGAGCCCTACAAGACAGCAAAAGGTGATG
AGCTGTCTAGTCGAATACAGAACATGTTGGGAAACTACGAAGAAGTGAAGGAGTTCCTTAGTACTAAGTCTCACACTCATCGCCTGGATG
CTTCTGAAAATAGGTTGGGAAAGCCGAAATATCCTTTAATTCCTGACAAAGGGAGCAGCATTCCATCCAGCTCCTTCCACACTAGTGTCC
ACCACCAGTCCATTCACACTCCTGCGTCTGGACCACTTTCTGTTGGCAACATTAGCCACAATCCAAAGATGGCGCAGCCAAGAACTGAAC
CAATGCCAAGTCTCCATGCCAAAAGCTGCGGCCCACCGGACAGCCAGCACCTGACCCAGGATCGCCTTGGTCAGGAGGGGTTCGGCTCTA
GTCATCACAAGAAAGGTGACCGAAGAGCTGACGGAGACCACTGTGCTTCGGTGACAGATTCGGCTCCAGAGAGGGAGCTTTCTCCCTTAA
TCTCTTTGCCTTCCCCAGTTCCCCCTTTGTCACCTATACATTCCAACCAGCAAACTCTTCCCCGGACGCAAGGAAGCAGCAAGGTTCATG
GCAGCAGCAATAACAGTAAAGGCTATTGCCCAGCCAAATCTCCCAAGGACCTAGCAGTGAAAGTCCATGATAAAGAGACCCCTCAAGACA
GTTTGGTGGCCCCTGCCCAGCCGCCTTCTCAGACATTTCCACCTCCCTCCCTCCCCTCAAAAAGTGTTGCAATGCAGCAGAAGCCCACGG
CTTATGTCCGGCCCATGGATGGTCAAGATCAGGCCCCTAGTGAATCCCCTGAACTGAAACCACTGCCGGAGGACTATCGACAGCAGACCT
TTGAAAAAACAGACTTGAAAGTGCCTGCCAAAGCCAAGCTCACCAAACTGAAGATGCCTTCTCAGTCAGTTGAGCAGACCTACTCCAATG
AAGTCCATTGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCTTTGACAGCAATACATACGCCTAGTACAGCTGAGC
CATCCAAGTTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAAAACCAAAAACAATATGATACATCTTCAAAAACTC
ACTCAAATTCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGTGACAGTGAGGACAGTGACAGTGAACAAACCCCAG
AGAAGCCTCCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCAGTGGCATCAGCACATTCCAGCAGTGCAGAGTCAG
AAAGCACCAGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGTGACAGCGAAGAAAATGAGCCCCTAGAAACCCCAG
CTCCGGAGCCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACCAAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCC
CCAGGAGCACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGTGCCACGAGTCAGGAGCATTCTGAATCCAAAGATC
CTCCCCCTAAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCCGGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGC
AGGAGCCCCCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAGGCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGC
AGGGGGAAAGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAAGACAAGCCCAAGGTGAAGACGAAAGGACGGCCCC
GGGCCGCAGCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAGAAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGG
CTCTCTCAGGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCACTTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCC
CACCCCACAGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTCCAGGAGGACAGCCGCAAAGACAGACTCCCATTGC
CTTTGAGAGACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGCTTGATGGTGAAGATCACCCTAGACCTGCTCTCTC
GGATACCCCAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAGCCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGA
GGAGCTCAGACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGAGACTGTGATAACAAGAAAATCAGACTGGAGAAGG
AAATCAAATCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACAAAGCCCTCCAGGCCCTCCTCACAGTCCTCAAAGA
AGGAAATGCTCCCCCCGCCACCCGTGTCCTCGTCCTCCCAGAAGCCAGCCAAGCCTGCACTTAAGAGGTCAAGGCGGGAAGCAGACACCT
GTGGCCAGGACCCTCCCAAAAGTGCCAGCAGTACCAAGAGCAACCACAAAGACTCTTCCATTCCCAAGCAGAGAAGAGTAGAGGGGAAGG
GCTCCAGAAGCTCCTCGGAGCACAAGGGTTCTTCCGGAGATACTGCAAATCCTTTTCCAGTGCCTTCTTTGCCAAATGGTAACTCTAAAC
CAGGGAAGCCTCAAGTGAAGTTTGACAAACAACAAGCAGACCTTCACATGAGGGAGGCAAAAAAGATGAAGCAGAAAGCAGAGTTAATGA
AAAAGAAAATCACATTGCAAAATACATCAGATGGAATAAAACATGGCTTCCAGACAGACAACAGTAAGATATGCCAGTACCTGCTGCACC
TCTGCTCTTACCAGCATAAGTTCCAGCTACAGATGAGAGCAAGACAGAGCAACCAAGATGCCCAAGATATTGAGAGAGCTTCGTTTAGGA
GCCTGAATCTCCAAGCAGAGTCTGTTAGAGGATTTAATATGGGACGAGCAATCAGCACTGGCAGTCTGGCCAGCAGCACCCTCAACAAAC
TTGCTGTTCGACCTTTATCAGTTCAAGCTGAGATTCTGAAGAGGCTATCCTGCTCAGAGCTGTCGCTTTACCAGCCATTGCAAAACAGTT
CAAAAGAGAAGAATGACAAAGCTTCATGGGAGGAAAAGCCTAGAGAGATGAGTAAATCATACCATGATCTCAGTCAGGCCTCTCTCTATC
CACATCGGAAAAATGTCATTGTTAACATGGAACCCCCACCACAAACCGTTGCAGAGTTGGTGGGAAAACCTTCTCACCAGATGTCAAGAT
CTGATGCAGAATCTTTGGCAGGAGTGACAAAACTTAATAATTCAAAGTCTGTTGCGAGTTTAAATAGAAGTCCTGAAAGGAGGAAACATG
AATCAGACTCCTCATCCATTGAAGACCCTGGGCAAGCATATGTTCTAGGAATGACTATGCATAGTTCTGGAAACTCTTCATCCCAAGTAC
CCTTAAAAGAAAATGATGTGCTACACAAAAGATGGAGCATAGTATCTTCACCAGAAAGGGAGATCACCTTAGTGAACCTGAAAAAAGATG
CAAAGTATGGCTTGGGATTTCAAATTATTGGTGGGGAGAAGATGGGAAGACTGGACCTAGGCATATTTATCAGTTCAGTTGCCCCTGGAG
GACCAGCTGACTTGGATGGATGCTTGAAGCCAGGAGACCGTTTGATATCTGTGAATAGTGTGAGTCTGGAGGGAGTCAGCCACCATGCTG
CAATTGAAATTTTGCAAAATGCACCTGAAGATGTGACACTTGTTATCTCTCAGCCAAAAGAAAAGATATCCAAAGTGCCTTCTACTCCTG
TGCATCTCACCAATGAGATGAAAAACTACATGAAGAAATCTTCCTACATGCAAGACAGTGCTATAGATTCTTCTTCCAAGGATCACCACT
GGTCACGTGGTACCCTGAGGCACATCTCGGAGAACTCCTTTGGGCCATCTGGGGGCCTGCGGGAAGGAAGCCTGAGTTCTCAAGATTCCA
GGACTGAGAGTGCCAGCTTGTCTCAAAGCCAGGTCAATGGTTTCTTTGCCAGCCATTTAGGTGACCAAACCTGGCAGGAATCACAGCATG
GCAGCCCTTCCCCATCTGTAATATCCAAAGCCACCGAGAAAGAGACTTTCACTGATAGTAACCAAAGCAAAACTAAAAAGCCAGGCATTT
CTGATGTAACTGATTACTCAGACCGTGGAGATTCAGACATGGATGAAGCCACTTACTCCAGCAGTCAGGATCATCAAACACCAAAACAGG
AATCTTCCTCTTCAGTGAATACATCCAACAAGATGAATTTTAAAACTTTTTCTTCATCACCTCCTAAGCCTGGAGATATCTTTGAGGTTG
AACTGGCTAAAAATGATAACAGCTTGGGGATAAGTGTCACGGTACTGTTTGACAAGGGAGGTGTGAATACGAGTGTCAGACATGGTGGCA
TTTATGTGAAAGCTGTTATTCCCCAGGGAGCAGCAGAGTCTGATGGTAGAATTCACAAAGGTGATCGCGTCCTAGCTGTCAATGGAGTTA
GTCTAGAAGGAGCCACCCATAAGCAAGCTGTGGAAACACTGAGAAATACAGGACAGGTGGTTCATCTGTTATTAGAAAAGGGACAATCTC
CAACATCTAAAGAACATGTCCCGGTAACCCCACAGTGTACCCTTTCAGATCAGAATGCCCAAGGTCAAGGCCCAGAAAAAGTGAAGAAAA
CAACTCAGGTCAAAGACTACAGCTTTGTCACTGAAGAAAATACATTTGAGGTAAAATTATTTAAAAATAGCTCAGGTCTAGGATTCAGTT
TTTCTCGAGAAGATAATCTTATACCGGAGCAAATTAATGCCAGCATAGTAAGGGTTAAAAAGCTCTTTCCTGGACAGCCAGCAGCAGAAA
GTGGAAAAATTGATGTAGGAGATGTTATCTTGAAAGTGAATGGAGCCTCTTTGAAAGGACTATCTCAGCAGGAAGTCATATCTGCTCTCA
GGGGAACTGCTCCAGAAGTATTCTTGCTTCTCTGCAGACCTCCACCTGGTGTGCTACCGGAAATTGATACTGCGCTTTTGACCCCACTTC
AGTCTCCAGCACAAGTACTTCCAAACAGCAGTAAAGACTCTTCTCAGCCATCATGTGTGGAGCAAAGCACCAGCTCAGATGAAAATGAAA
TGTCAGACAAAAGCAAAAAACAGTGCAAGTCCCCATCCAGAAGAGACAGTTACAGTGACAGCAGTGGGAGTGGAGAAGATGACTTAGTGA
CAGCTCCAGCAAACATATCAAATTCGACCTGGAGTTCAGCTTTGCATCAGACTCTAAGCAACATGGTATCACAGGCACAGAGTCATCATG
AAGCACCCAAGAGTCAAGAAGATACCATTTGTACCATGTTTTACTATCCTCAGAAAATTCCCAATAAACCAGAGTTTGAGGACAGTAATC
CTTCCCCTCTACCACCGGATATGGCTCCTGGGCAGAGTTATCAACCCCAATCAGAATCTGCTTCCTCTAGTTCGATGGATAAGTATCATA
TACATCACATTTCTGAACCAACTAGACAAGAAAACTGGACACCTTTGAAAAATGACTTGGAAAATCACCTTGAAGACTTTGAACTGGAAG
TAGAACTCCTCATTACCCTAATTAAATCAGAAAAAGGAAGCCTGGGTTTTACAGTAACCAAAGGCAATCAGAGAATTGGTTGTTATGTTC
ATGATGTCATACAGGATCCAGCCAAAAGTGATGGAAGGCTAAAACCTGGGGACCGGCTCATAAAGGTTAATGATACAGATGTTACTAATA
TGACTCATACAGATGCAGTTAATCTGCTCCGGGCTGCATCCAAAACAGTCAGATTAGTTATTGGACGAGTTCTAGAATTACCCAGAATAC
CAATGTTGCCTCATTTGCTACCGGACATAACACTAACGTGCAACAAAGAGGAGTTGGGTTTTTCCTTATGTGGAGGTCATGACAGCCTTT
ATCAAGTGGTATATATTAGTGATATTAATCCAAGGTCCGTCGCAGCCATTGAGGGTAATCTCCAGCTATTAGATGTCATCCATTATGTGA
ACGGAGTCAGCACACAAGGAATGACCTTGGAGGAAGTTAACAGAGCATTAGACATGTCACTTCCTTCATTGGTATTGAAAGCAACAAGAA
ATGATCTTCCAGTGGTCCCCAGCTCAAAGAGGTCTGCTGTTTCAGCTCCAAAGTCAACCAAAGGCAATGGTTCCTACAGTGTGGGGTCTT
GCAGCCAGCCTGCCCTCACTCCTAATGATTCATTCTCCACGGTTGCTGGGGAAGAAATAAATGAAATATCGTACCCCAAAGGAAAATGTT
CTACTTATCAGATAAAGGGATCACCAAACTTGACTCTGCCCAAAGAATCTTATATACAAGAAGATGACATTTATGATGATTCCCAAGAAG
CTGAAGTTATCCAGTCTCTGCTGGATGTTGTGGATGAGGAAGCCCAGAATCTTTTAAACGAAAATAATGCAGCAGGATACTCCTGTGGTC
CAGGTACATTAAAGATGAATGGGAAGTTATCAGAAGAGAGAACAGAAGATACAGACTGCGATGGTTCACCTTTACCTGAGTATTTTACTG
AGGCCACCAAAATGAATGGCTGTGAAGAATATTGTGAAGAAAAAGTAAAAAGTGAAAGCTTAATTCAGAAGCCACAAGAAAAGAAGACTG
ATGATGATGAAATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCATGAAGATTCTGATAAAGATCATTCCTTTCTGACAA
ACGATGAGCTCGCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACGGGTGCCAACTTAAAATCAGTCATTCGAGTCCTGC
GGGGTTTGCTAGATCAAGGAATTCCTTCTAAGGAGCTGGAGAATCTTCAAGAATTAAAACCTTTGGATCAGTGTCTAATTGGGCAAACTA
AGGAAAACAGAAGGAAGAACAGATATAAAAATATACTTCCCTATGATGCTACAAGAGTGCCTCTTGGAGATGAAGGTGGCTATATCAATG
CCAGCTTCATTAAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAAGGACCACTGCCTACAACTGTTGGAGACTTCTGGC
AGATGATTTGGGAGCAAAAATCCACAGTGATAGCCATGATGACTCAAGAAGTAGAAGGAGAAAAAATCAAATGCCAGCGCTATTGGCCCA
ACATCCTAGGCAAAACAACAATGGTCAGCAACAGACTTCGACTGGCTCTTGTGAGAATGCAGCAGCTGAAGGGCTTTGTGGTGAGGGCAA
TGACCCTTGAAGATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTCACTGCCTGGCCAGACCATGATACACCTTCTCAAC
CAGATGATCTGCTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCAATCATTACGCACTGCAGTGCTGGCATTGGACGTT
CAGGGACCCTGATTTGCATAGATGTGGTTCTGGGATTAATCAGTCAGGATCTTGATTTTGACATCTCTGATTTGGTGCGCTGCATGAGAC
TACAAAGACACGGAATGGTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTCATCCTTTATGTCCTGACACGTCTTCAAGCAGAAG
AAGAGCAAAAACAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATGCATTTCCATTTCTCTCCTTAACCTCCAGCAGACT
CCTGCTCTCTATCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGCATGTTCTCCTCTATCTTAGAGGGGTATTCTTCTTGAA
AATAAAAAATATTGAAATGCTGTATTTTTACAGCTACTTTAACCTATGATAATTATTTACAAAATTTTAACACTAACCAAACAATGCAGA
TCTTAGGGATGATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACATGGTGAGTCTATTTTTAATGCACCAATCTTGTTTA
TAGCAAAAATGTTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTGAAACCAGTATTTAAGCTTTAAATGACAGTAATAT
TGGCATAGAAAAAAGTAGCAAATGTTTACTGTATCAATTTCTAATGTTTACTATATAGAATTTCCTGTAATATATTTATATACTTTTTCA
TGAAAATGGAGTTATCAGTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATTATCTCACTTTGTAAATAAAAACACACCTTAAAAC
ATGAACAAGCCAAAACTGTGTGCAG

>2666_2666_12_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000395146_PTPN13_chr4_87666119_ENST00000436978_length(amino acids)=2652AA_BP=989
METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL
DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG
SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ
DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYS
NEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQT
PEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPE
GPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTS
LQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQ
GPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSE
KRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREAD
TCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAKKMKQKAEL
MKKKITLQNTSDGIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRGFNMGRAISTGSLASSTLN
KLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWEEKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMS
RSDAESLAGVTKLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKRWSIVSSPEREITLVNLKK
DAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPST
PVHLTNEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQVNGFFASHLGDQTWQESQ
HGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFE
VELAKNDNSLGISVTVLFDKGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQ
SPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAA
ESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDEN
EMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDS
NPSPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLGFTVTKGNQRIGCY
VHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDS
LYQVVYISDINPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSAPKSTKGNGSYSVG
SCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSC
GPGTLKMNGKLSEERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFL
TNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYI
NASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVR
AMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCM
RLQRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK

--------------------------------------------------------------
>2666_2666_13_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000395146_PTPN13_chr4_87718027_ENST00000427191_length(transcript)=4958nt_BP=3239nt
GAGCTTGCCAGCCAGCTAGCGAGCGACGGGCGCGCGCGGCCCCTGCGCACTCGGCCGCCGCCTGCGCGCGTTGCGGCCGCAGCTGCACCT
TTGCCTCCGCGGTTCCGCAGCCGAGCCCCGGGAGGAGGCGCTCCCCTGCGTCGTCCGCACTTGCGCCCTTTCCCACCGCAACAGGTCAGG
GGAGGGCGGAGGTGACGAGGGCGCCCGACCCGGGACTAGAGGACGGAAGGGTCTGGAAGATGAACAGACTAGCCACTTTGCATTGACTGG
AAACAATGGCATTTACAGAAAGAGTCAACAGCAGTGGCAACAGTTTGTACAATGACGACAGAAACCTGCTTCGAATTAGAGAGAAGGAAA
GACGCAACCAGGAAGCCCACCAAGAGAAAGAGGCATTTCCTGAAAAGATTCCCCTTTTTGGAGAGCCCTACAAGACAGCAAAAGGTGATG
AGCTGTCTAGTCGAATACAGAACATGTTGGGAAACTACGAAGAAGTGAAGGAGTTCCTTAGTACTAAGTCTCACACTCATCGCCTGGATG
CTTCTGAAAATAGGTTGGGAAAGCCGAAATATCCTTTAATTCCTGACAAAGGGAGCAGCATTCCATCCAGCTCCTTCCACACTAGTGTCC
ACCACCAGTCCATTCACACTCCTGCGTCTGGACCACTTTCTGTTGGCAACATTAGCCACAATCCAAAGATGGCGCAGCCAAGAACTGAAC
CAATGCCAAGTCTCCATGCCAAAAGCTGCGGCCCACCGGACAGCCAGCACCTGACCCAGGATCGCCTTGGTCAGGAGGGGTTCGGCTCTA
GTCATCACAAGAAAGGTGACCGAAGAGCTGACGGAGACCACTGTGCTTCGGTGACAGATTCGGCTCCAGAGAGGGAGCTTTCTCCCTTAA
TCTCTTTGCCTTCCCCAGTTCCCCCTTTGTCACCTATACATTCCAACCAGCAAACTCTTCCCCGGACGCAAGGAAGCAGCAAGGTTCATG
GCAGCAGCAATAACAGTAAAGGCTATTGCCCAGCCAAATCTCCCAAGGACCTAGCAGTGAAAGTCCATGATAAAGAGACCCCTCAAGACA
GTTTGGTGGCCCCTGCCCAGCCGCCTTCTCAGACATTTCCACCTCCCTCCCTCCCCTCAAAAAGTGTTGCAATGCAGCAGAAGCCCACGG
CTTATGTCCGGCCCATGGATGGTCAAGATCAGGCCCCTAGTGAATCCCCTGAACTGAAACCACTGCCGGAGGACTATCGACAGCAGACCT
TTGAAAAAACAGACTTGAAAGTGCCTGCCAAAGCCAAGCTCACCAAACTGAAGATGCCTTCTCAGTCAGTTGAGCAGACCTACTCCAATG
AAGTCCATTGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCTTTGACAGCAATACATACGCCTAGTACAGCTGAGC
CATCCAAGTTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAAAACCAAAAACAATATGATACATCTTCAAAAACTC
ACTCAAATTCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGTGACAGTGAGGACAGTGACAGTGAACAAACCCCAG
AGAAGCCTCCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCAGTGGCATCAGCACATTCCAGCAGTGCAGAGTCAG
AAAGCACCAGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGTGACAGCGAAGAAAATGAGCCCCTAGAAACCCCAG
CTCCGGAGCCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACCAAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCC
CCAGGAGCACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGTGCCACGAGTCAGGAGCATTCTGAATCCAAAGATC
CTCCCCCTAAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCCGGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGC
AGGAGCCCCCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAGGCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGC
AGGGGGAAAGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAAGACAAGCCCAAGGTGAAGACGAAAGGACGGCCCC
GGGCCGCAGCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAGAAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGG
CTCTCTCAGGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCACTTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCC
CACCCCACAGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTCCAGGAGGACAGCCGCAAAGACAGACTCCCATTGC
CTTTGAGAGACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGCTTGATGGTGAAGATCACCCTAGACCTGCTCTCTC
GGATACCCCAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAGCCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGA
GGAGCTCAGACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGAGACTGTGATAACAAGAAAATCAGACTGGAGAAGG
AAATCAAATCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACAAAGCCCTCCAGGCCCTCCTCACAGTCCTCAAAGA
AGGAAATGCTCCCCCCGCCACCCGTGTCCTCGTCCTCCCAGAAGCCAGCCAAGCCTGCACTTAAGAGGTCAAGGCGGGAAGCAGACACCT
GTGGCCAGGACCCTCCCAAAAGTGCCAGCAGTACCAAGAGCAACCACAAAGACTCTTCCATTCCCAAGCAGAGAAGAGTAGAGGGGAAGG
GCTCCAGAAGCTCCTCGGAGCACAAGGGTTCTTCCGGAGATACTGCAAATCCTTTTCCAGTGCCTTCTTTGCCAAATGGTAACTCTAAAC
CAGGGAAGCCTCAAGTGAAGTTTGACAAACAACAAGCAGACCTTCACATGAGGGAGGCAAAAAAGATGAAGCAGAAAGCAGAGTTAATGG
CCACCAAAATGAATGGCTGTGAAGAATATTGTGAAGAAAAAGTAAAAAGTGAAAGCTTAATTCAGAAGCCACAAGAAAAGAAGACTGATG
ATGATGAAATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCATGAAGATTCTGATAAAGATCATTCCTTTCTGACAAACG
ATGAGCTCGCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACGGGTGCCAACTTAAAATCAGTCATTCGAGTCCTGCGGG
GTTTGCTAGATCAAGGAATTCCTTCTAAGGAGCTGGAGAATCTTCAAGAATTAAAACCTTTGGATCAGTGTCTAATTGGGCAAACTAAGG
AAAACAGAAGGAAGAACAGATATAAAAATATACTTCCCTATGATGCTACAAGAGTGCCTCTTGGAGATGAAGGTGGCTATATCAATGCCA
GCTTCATTAAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAAGGACCACTGCCTACAACTGTTGGAGACTTCTGGCAGA
TGATTTGGGAGCAAAAATCCACAGTGATAGCCATGATGACTCAAGAAGTAGAAGGAGAAAAAATCAAATGCCAGCGCTATTGGCCCAACA
TCCTAGGCAAAACAACAATGGTCAGCAACAGACTTCGACTGGCTCTTGTGAGAATGCAGCAGCTGAAGGGCTTTGTGGTGAGGGCAATGA
CCCTTGAAGATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTCACTGCCTGGCCAGACCATGATACACCTTCTCAACCAG
ATGATCTGCTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCAATCATTACGCACTGCAGTGCTGGCATTGGACGTTCAG
GGACCCTGATTTGCATAGATGTGGTTCTGGGATTAATCAGTCAGGATCTTGATTTTGACATCTCTGATTTGGTGCGCTGCATGAGACTAC
AAAGACACGGAATGGTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTCATCCTTTATGTCCTGACACGTCTTCAAGCAGAAGAAG
AGCAAAAACAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATGCATTTCCATTTCTCTCCTTAACCTCCAGCAGACTCCT
GCTCTCTATCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGCATGTTCTCCTCTATCTTAGAGGGGTATTCTTCTTGAAAAT
AAAAAATATTGAAATGCTGTATTTTTACAGCTACTTTAACCTATGATAATTATTTACAAAATTTTAACACTAACCAAACAATGCAGATCT
TAGGGATGATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACATGGTGAGTCTATTTTTAATGCACCAATCTTGTTTATAG
CAAAAATGTTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTGAAACCAGTATTTAAGCTTTAAATGACAGTAATATTGG
CATAGAAAAAAGTAGCAAATGTTTACTGTATCAATTTCTAATGTTTACTATATAGAATTTCCTGTAATATATTTATATACTTTTTCATGA
AAATGGAGTTATCAGTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATTATCTCACTTTGTAAATAAAAACACACCTTAAAACATG
AACAAGCC

>2666_2666_13_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000395146_PTPN13_chr4_87718027_ENST00000427191_length(amino acids)=1361AA_BP=989
METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL
DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG
SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ
DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYS
NEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQT
PEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPE
GPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTS
LQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQ
GPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSE
KRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREAD
TCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAKKMKQKAEL
MATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVL
RGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFW
QMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQ
PDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRLQAE
EEQKQQPQLLK

--------------------------------------------------------------
>2666_2666_14_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000395146_PTPN13_chr4_87718027_ENST00000436978_length(transcript)=4972nt_BP=3239nt
GAGCTTGCCAGCCAGCTAGCGAGCGACGGGCGCGCGCGGCCCCTGCGCACTCGGCCGCCGCCTGCGCGCGTTGCGGCCGCAGCTGCACCT
TTGCCTCCGCGGTTCCGCAGCCGAGCCCCGGGAGGAGGCGCTCCCCTGCGTCGTCCGCACTTGCGCCCTTTCCCACCGCAACAGGTCAGG
GGAGGGCGGAGGTGACGAGGGCGCCCGACCCGGGACTAGAGGACGGAAGGGTCTGGAAGATGAACAGACTAGCCACTTTGCATTGACTGG
AAACAATGGCATTTACAGAAAGAGTCAACAGCAGTGGCAACAGTTTGTACAATGACGACAGAAACCTGCTTCGAATTAGAGAGAAGGAAA
GACGCAACCAGGAAGCCCACCAAGAGAAAGAGGCATTTCCTGAAAAGATTCCCCTTTTTGGAGAGCCCTACAAGACAGCAAAAGGTGATG
AGCTGTCTAGTCGAATACAGAACATGTTGGGAAACTACGAAGAAGTGAAGGAGTTCCTTAGTACTAAGTCTCACACTCATCGCCTGGATG
CTTCTGAAAATAGGTTGGGAAAGCCGAAATATCCTTTAATTCCTGACAAAGGGAGCAGCATTCCATCCAGCTCCTTCCACACTAGTGTCC
ACCACCAGTCCATTCACACTCCTGCGTCTGGACCACTTTCTGTTGGCAACATTAGCCACAATCCAAAGATGGCGCAGCCAAGAACTGAAC
CAATGCCAAGTCTCCATGCCAAAAGCTGCGGCCCACCGGACAGCCAGCACCTGACCCAGGATCGCCTTGGTCAGGAGGGGTTCGGCTCTA
GTCATCACAAGAAAGGTGACCGAAGAGCTGACGGAGACCACTGTGCTTCGGTGACAGATTCGGCTCCAGAGAGGGAGCTTTCTCCCTTAA
TCTCTTTGCCTTCCCCAGTTCCCCCTTTGTCACCTATACATTCCAACCAGCAAACTCTTCCCCGGACGCAAGGAAGCAGCAAGGTTCATG
GCAGCAGCAATAACAGTAAAGGCTATTGCCCAGCCAAATCTCCCAAGGACCTAGCAGTGAAAGTCCATGATAAAGAGACCCCTCAAGACA
GTTTGGTGGCCCCTGCCCAGCCGCCTTCTCAGACATTTCCACCTCCCTCCCTCCCCTCAAAAAGTGTTGCAATGCAGCAGAAGCCCACGG
CTTATGTCCGGCCCATGGATGGTCAAGATCAGGCCCCTAGTGAATCCCCTGAACTGAAACCACTGCCGGAGGACTATCGACAGCAGACCT
TTGAAAAAACAGACTTGAAAGTGCCTGCCAAAGCCAAGCTCACCAAACTGAAGATGCCTTCTCAGTCAGTTGAGCAGACCTACTCCAATG
AAGTCCATTGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCTTTGACAGCAATACATACGCCTAGTACAGCTGAGC
CATCCAAGTTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAAAACCAAAAACAATATGATACATCTTCAAAAACTC
ACTCAAATTCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGTGACAGTGAGGACAGTGACAGTGAACAAACCCCAG
AGAAGCCTCCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCAGTGGCATCAGCACATTCCAGCAGTGCAGAGTCAG
AAAGCACCAGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGTGACAGCGAAGAAAATGAGCCCCTAGAAACCCCAG
CTCCGGAGCCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACCAAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCC
CCAGGAGCACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGTGCCACGAGTCAGGAGCATTCTGAATCCAAAGATC
CTCCCCCTAAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCCGGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGC
AGGAGCCCCCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAGGCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGC
AGGGGGAAAGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAAGACAAGCCCAAGGTGAAGACGAAAGGACGGCCCC
GGGCCGCAGCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAGAAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGG
CTCTCTCAGGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCACTTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCC
CACCCCACAGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTCCAGGAGGACAGCCGCAAAGACAGACTCCCATTGC
CTTTGAGAGACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGCTTGATGGTGAAGATCACCCTAGACCTGCTCTCTC
GGATACCCCAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAGCCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGA
GGAGCTCAGACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGAGACTGTGATAACAAGAAAATCAGACTGGAGAAGG
AAATCAAATCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACAAAGCCCTCCAGGCCCTCCTCACAGTCCTCAAAGA
AGGAAATGCTCCCCCCGCCACCCGTGTCCTCGTCCTCCCAGAAGCCAGCCAAGCCTGCACTTAAGAGGTCAAGGCGGGAAGCAGACACCT
GTGGCCAGGACCCTCCCAAAAGTGCCAGCAGTACCAAGAGCAACCACAAAGACTCTTCCATTCCCAAGCAGAGAAGAGTAGAGGGGAAGG
GCTCCAGAAGCTCCTCGGAGCACAAGGGTTCTTCCGGAGATACTGCAAATCCTTTTCCAGTGCCTTCTTTGCCAAATGGTAACTCTAAAC
CAGGGAAGCCTCAAGTGAAGTTTGACAAACAACAAGCAGACCTTCACATGAGGGAGGCAAAAAAGATGAAGCAGAAAGCAGAGTTAATGG
CCACCAAAATGAATGGCTGTGAAGAATATTGTGAAGAAAAAGTAAAAAGTGAAAGCTTAATTCAGAAGCCACAAGAAAAGAAGACTGATG
ATGATGAAATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCATGAAGATTCTGATAAAGATCATTCCTTTCTGACAAACG
ATGAGCTCGCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACGGGTGCCAACTTAAAATCAGTCATTCGAGTCCTGCGGG
GTTTGCTAGATCAAGGAATTCCTTCTAAGGAGCTGGAGAATCTTCAAGAATTAAAACCTTTGGATCAGTGTCTAATTGGGCAAACTAAGG
AAAACAGAAGGAAGAACAGATATAAAAATATACTTCCCTATGATGCTACAAGAGTGCCTCTTGGAGATGAAGGTGGCTATATCAATGCCA
GCTTCATTAAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAAGGACCACTGCCTACAACTGTTGGAGACTTCTGGCAGA
TGATTTGGGAGCAAAAATCCACAGTGATAGCCATGATGACTCAAGAAGTAGAAGGAGAAAAAATCAAATGCCAGCGCTATTGGCCCAACA
TCCTAGGCAAAACAACAATGGTCAGCAACAGACTTCGACTGGCTCTTGTGAGAATGCAGCAGCTGAAGGGCTTTGTGGTGAGGGCAATGA
CCCTTGAAGATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTCACTGCCTGGCCAGACCATGATACACCTTCTCAACCAG
ATGATCTGCTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCAATCATTACGCACTGCAGTGCTGGCATTGGACGTTCAG
GGACCCTGATTTGCATAGATGTGGTTCTGGGATTAATCAGTCAGGATCTTGATTTTGACATCTCTGATTTGGTGCGCTGCATGAGACTAC
AAAGACACGGAATGGTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTCATCCTTTATGTCCTGACACGTCTTCAAGCAGAAGAAG
AGCAAAAACAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATGCATTTCCATTTCTCTCCTTAACCTCCAGCAGACTCCT
GCTCTCTATCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGCATGTTCTCCTCTATCTTAGAGGGGTATTCTTCTTGAAAAT
AAAAAATATTGAAATGCTGTATTTTTACAGCTACTTTAACCTATGATAATTATTTACAAAATTTTAACACTAACCAAACAATGCAGATCT
TAGGGATGATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACATGGTGAGTCTATTTTTAATGCACCAATCTTGTTTATAG
CAAAAATGTTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTGAAACCAGTATTTAAGCTTTAAATGACAGTAATATTGG
CATAGAAAAAAGTAGCAAATGTTTACTGTATCAATTTCTAATGTTTACTATATAGAATTTCCTGTAATATATTTATATACTTTTTCATGA
AAATGGAGTTATCAGTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATTATCTCACTTTGTAAATAAAAACACACCTTAAAACATG
AACAAGCCAAAACTGTGTGCAG

>2666_2666_14_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000395146_PTPN13_chr4_87718027_ENST00000436978_length(amino acids)=1361AA_BP=989
METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL
DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG
SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ
DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYS
NEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQT
PEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPE
GPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTS
LQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQ
GPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSE
KRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREAD
TCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAKKMKQKAEL
MATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVL
RGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFW
QMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQ
PDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRLQAE
EEQKQQPQLLK

--------------------------------------------------------------
>2666_2666_15_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000544085_PTPN13_chr4_87666119_ENST00000427191_length(transcript)=7581nt_BP=2061nt
GTAGTCCCGTAACATCGGGGCGCCGCGCCGGGACGCGTCCCCGCCCGGCTCCGCCAAATGGTGAGCGCGGCGCTGGCAGCAGGGCCCGCG
GGGTGAAGGCGCTCATGGACGGAAGACCCCTGGCTCTATAAGCTGAATTATGGCAGCCCAGTCAAGCAGACCTACTCCAATGAAGTCCAT
TGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCTTTGACAGCAATACATACGCCTAGTACAGCTGAGCCATCCAAG
TTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAAAACCAAAAACAATATGATACATCTTCAAAAACTCACTCAAAT
TCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGTGACAGTGAGGACAGTGACAGTGAACAAACCCCAGAGAAGCCT
CCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCAGTGGCATCAGCACATTCCAGCAGTGCAGAGTCAGAAAGCACC
AGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGTGACAGCGAAGAAAATGAGCCCCTAGAAACCCCAGCTCCGGAG
CCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACCAAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCCCCAGGAGC
ACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGTGCCACGAGTCAGGAGCATTCTGAATCCAAAGATCCTCCCCCT
AAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCCGGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGCAGGAGCCC
CCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAGGCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGCAGGGGGAA
AGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAAGACAAGCCCAAGGTGAAGACGAAAGGACGGCCCCGGGCCGCA
GCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAGAAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGGCTCTCTCA
GGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCACTTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCCCACCCCAC
AGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTCCAGGAGGACAGCCGCAAAGACAGACTCCCATTGCCTTTGAGA
GACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGCTTGATGGTGAAGATCACCCTAGACCTGCTCTCTCGGATACCC
CAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAGCCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGAGGAGCTCA
GACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGAGACTGTGATAACAAGAAAATCAGACTGGAGAAGGAAATCAAA
TCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACAAAGCCCTCCAGGCCCTCCTCACAGTCCTCAAAGAAGGAAATG
CTCCCCCCGCCACCCGTGTCCTCGTCCTCCCAGAAGCCAGCCAAGCCTGCACTTAAGAGGTCAAGGCGGGAAGCAGACACCTGTGGCCAG
GACCCTCCCAAAAGTGCCAGCAGTACCAAGAGCAACCACAAAGACTCTTCCATTCCCAAGCAGAGAAGAGTAGAGGGGAAGGGCTCCAGA
AGCTCCTCGGAGCACAAGGGTTCTTCCGGAGATACTGCAAATCCTTTTCCAGTGCCTTCTTTGCCAAATGGTAACTCTAAACCAGGGAAG
CCTCAAGTGAAGTTTGACAAACAACAAGCAGACCTTCACATGAGGGAGGCAAAAAAGATGAAGCAGAAAGCAGAGTTAATGAAAAAGAAA
ATCACATTGCAAAATACATCAGATGGAATAAAACATGGCTTCCAGACAGACAACAGTAAGATATGCCAGTACCTGCTGCACCTCTGCTCT
TACCAGCATAAGTTCCAGCTACAGATGAGAGCAAGACAGAGCAACCAAGATGCCCAAGATATTGAGAGAGCTTCGTTTAGGAGCCTGAAT
CTCCAAGCAGAGTCTGTTAGAGGATTTAATATGGGACGAGCAATCAGCACTGGCAGTCTGGCCAGCAGCACCCTCAACAAACTTGCTGTT
CGACCTTTATCAGTTCAAGCTGAGATTCTGAAGAGGCTATCCTGCTCAGAGCTGTCGCTTTACCAGCCATTGCAAAACAGTTCAAAAGAG
AAGAATGACAAAGCTTCATGGGAGGAAAAGCCTAGAGAGATGAGTAAATCATACCATGATCTCAGTCAGGCCTCTCTCTATCCACATCGG
AAAAATGTCATTGTTAACATGGAACCCCCACCACAAACCGTTGCAGAGTTGGTGGGAAAACCTTCTCACCAGATGTCAAGATCTGATGCA
GAATCTTTGGCAGGAGTGACAAAACTTAATAATTCAAAGTCTGTTGCGAGTTTAAATAGAAGTCCTGAAAGGAGGAAACATGAATCAGAC
TCCTCATCCATTGAAGACCCTGGGCAAGCATATGTTCTAGATGTGCTACACAAAAGATGGAGCATAGTATCTTCACCAGAAAGGGAGATC
ACCTTAGTGAACCTGAAAAAAGATGCAAAGTATGGCTTGGGATTTCAAATTATTGGTGGGGAGAAGATGGGAAGACTGGACCTAGGCATA
TTTATCAGTTCAGTTGCCCCTGGAGGACCAGCTGACTTGGATGGATGCTTGAAGCCAGGAGACCGTTTGATATCTGTGAATAGTGTGAGT
CTGGAGGGAGTCAGCCACCATGCTGCAATTGAAATTTTGCAAAATGCACCTGAAGATGTGACACTTGTTATCTCTCAGCCAAAAGAAAAG
ATATCCAAAGTGCCTTCTACTCCTGTGCATCTCACCAATGAGATGAAAAACTACATGAAGAAATCTTCCTACATGCAAGACAGTGCTATA
GATTCTTCTTCCAAGGATCACCACTGGTCACGTGGTACCCTGAGGCACATCTCGGAGAACTCCTTTGGGCCATCTGGGGGCCTGCGGGAA
GGAAGCCTGAGTTCTCAAGATTCCAGGACTGAGAGTGCCAGCTTGTCTCAAAGCCAGGTCAATGGTTTCTTTGCCAGCCATTTAGGTGAC
CAAACCTGGCAGGAATCACAGCATGGCAGCCCTTCCCCATCTGTAATATCCAAAGCCACCGAGAAAGAGACTTTCACTGATAGTAACCAA
AGCAAAACTAAAAAGCCAGGCATTTCTGATGTAACTGATTACTCAGACCGTGGAGATTCAGACATGGATGAAGCCACTTACTCCAGCAGT
CAGGATCATCAAACACCAAAACAGGAATCTTCCTCTTCAGTGAATACATCCAACAAGATGAATTTTAAAACTTTTTCTTCATCACCTCCT
AAGCCTGGAGATATCTTTGAGGTTGAACTGGCTAAAAATGATAACAGCTTGGGGATAAGTGTCACGGGAGGTGTGAATACGAGTGTCAGA
CATGGTGGCATTTATGTGAAAGCTGTTATTCCCCAGGGAGCAGCAGAGTCTGATGGTAGAATTCACAAAGGTGATCGCGTCCTAGCTGTC
AATGGAGTTAGTCTAGAAGGAGCCACCCATAAGCAAGCTGTGGAAACACTGAGAAATACAGGACAGGTGGTTCATCTGTTATTAGAAAAG
GGACAATCTCCAACATCTAAAGAACATGTCCCGGTAACCCCACAGTGTACCCTTTCAGATCAGAATGCCCAAGGTCAAGGCCCAGAAAAA
GTGAAGAAAACAACTCAGGTCAAAGACTACAGCTTTGTCACTGAAGAAAATACATTTGAGGTAAAATTATTTAAAAATAGCTCAGGTCTA
GGATTCAGTTTTTCTCGAGAAGATAATCTTATACCGGAGCAAATTAATGCCAGCATAGTAAGGGTTAAAAAGCTCTTTCCTGGACAGCCA
GCAGCAGAAAGTGGAAAAATTGATGTAGGAGATGTTATCTTGAAAGTGAATGGAGCCTCTTTGAAAGGACTATCTCAGCAGGAAGTCATA
TCTGCTCTCAGGGGAACTGCTCCAGAAGTATTCTTGCTTCTCTGCAGACCTCCACCTGGTGTGCTACCGGAAATTGATACTGCGCTTTTG
ACCCCACTTCAGTCTCCAGCACAAGTACTTCCAAACAGCAGTAAAGACTCTTCTCAGCCATCATGTGTGGAGCAAAGCACCAGCTCAGAT
GAAAATGAAATGTCAGACAAAAGCAAAAAACAGTGCAAGTCCCCATCCAGAAGAGACAGTTACAGTGACAGCAGTGGGAGTGGAGAAGAT
GACTTAGTGACAGCTCCAGCAAACATATCAAATTCGACCTGGAGTTCAGCTTTGCATCAGACTCTAAGCAACATGGTATCACAGGCACAG
AGTCATCATGAAGCACCCAAGAGTCAAGAAGATACCATTTGTACCATGTTTTACTATCCTCAGAAAATTCCCAATAAACCAGAGTTTGAG
GACAGTAATCCTTCCCCTCTACCACCGGATATGGCTCCTGGGCAGAGTTATCAACCCCAATCAGAATCTGCTTCCTCTAGTTCGATGGAT
AAGTATCATATACATCACATTTCTGAACCAACTAGACAAGAAAACTGGACACCTTTGAAAAATGACTTGGAAAATCACCTTGAAGACTTT
GAACTGGAAGTAGAACTCCTCATTACCCTAATTAAATCAGAAAAAGGAAGCCTGGGTTTTACAGTAACCAAAGGCAATCAGAGAATTGGT
TGTTATGTTCATGATGTCATACAGGATCCAGCCAAAAGTGATGGAAGGCTAAAACCTGGGGACCGGCTCATAAAGGTTAATGATACAGAT
GTTACTAATATGACTCATACAGATGCAGTTAATCTGCTCCGGGCTGCATCCAAAACAGTCAGATTAGTTATTGGACGAGTTCTAGAATTA
CCCAGAATACCAATGTTGCCTCATTTGCTACCGGACATAACACTAACGTGCAACAAAGAGGAGTTGGGTTTTTCCTTATGTGGAGGTCAT
GACAGCCTTTATCAAGTGGTATATATTAGTGATATTAATCCAAGGTCCGTCGCAGCCATTGAGGGTAATCTCCAGCTATTAGATGTCATC
CATTATGTGAACGGAGTCAGCACACAAGGAATGACCTTGGAGGAAGTTAACAGAGCATTAGACATGTCACTTCCTTCATTGGTATTGAAA
GCAACAAGAAATGATCTTCCAGTGGTCCCCAGCTCAAAGAGGTCTGCTGTTTCAGCTCCAAAGTCAACCAAAGGCAATGGTTCCTACAGT
GTGGGGTCTTGCAGCCAGCCTGCCCTCACTCCTAATGATTCATTCTCCACGGTTGCTGGGGAAGAAATAAATGAAATATCGTACCCCAAA
GGAAAATGTTCTACTTATCAGATAAAGGGATCACCAAACTTGACTCTGCCCAAAGAATCTTATATACAAGAAGATGACATTTATGATGAT
TCCCAAGAAGCTGAAGTTATCCAGTCTCTGCTGGATGTTGTGGATGAGGAAGCCCAGAATCTTTTAAACGAAAATAATGCAGCAGGATAC
TCCTGTGGTCCAGGTACATTAAAGATGAATGGGAAGTTATCAGAAGAGAGAACAGAAGATACAGACTGCGATGGTTCACCTTTACCTGAG
TATTTTACTGAGGCCACCAAAATGAATGGCTGTGAAGAATATTGTGAAGAAAAAGTAAAAAGTGAAAGCTTAATTCAGAAGCCACAAGAA
AAGAAGACTGATGATGATGAAATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCATGAAGATTCTGATAAAGATCATTCC
TTTCTGACAAACGATGAGCTCGCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACGGGTGCCAACTTAAAATCAGTCATT
CGAGTCCTGCGGGGTTTGCTAGATCAAGGAATTCCTTCTAAGGAGCTGGAGAATCTTCAAGAATTAAAACCTTTGGATCAGTGTCTAATT
GGGCAAACTAAGGAAAACAGAAGGAAGAACAGATATAAAAATATACTTCCCTATGATGCTACAAGAGTGCCTCTTGGAGATGAAGGTGGC
TATATCAATGCCAGCTTCATTAAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAAGGACCACTGCCTACAACTGTTGGA
GACTTCTGGCAGATGATTTGGGAGCAAAAATCCACAGTGATAGCCATGATGACTCAAGAAGTAGAAGGAGAAAAAATCAAATGCCAGCGC
TATTGGCCCAACATCCTAGGCAAAACAACAATGGTCAGCAACAGACTTCGACTGGCTCTTGTGAGAATGCAGCAGCTGAAGGGCTTTGTG
GTGAGGGCAATGACCCTTGAAGATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTCACTGCCTGGCCAGACCATGATACA
CCTTCTCAACCAGATGATCTGCTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCAATCATTACGCACTGCAGTGCTGGC
ATTGGACGTTCAGGGACCCTGATTTGCATAGATGTGGTTCTGGGATTAATCAGTCAGGATCTTGATTTTGACATCTCTGATTTGGTGCGC
TGCATGAGACTACAAAGACACGGAATGGTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTCATCCTTTATGTCCTGACACGTCTT
CAAGCAGAAGAAGAGCAAAAACAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATGCATTTCCATTTCTCTCCTTAACCT
CCAGCAGACTCCTGCTCTCTATCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGCATGTTCTCCTCTATCTTAGAGGGGTAT
TCTTCTTGAAAATAAAAAATATTGAAATGCTGTATTTTTACAGCTACTTTAACCTATGATAATTATTTACAAAATTTTAACACTAACCAA
ACAATGCAGATCTTAGGGATGATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACATGGTGAGTCTATTTTTAATGCACCA
ATCTTGTTTATAGCAAAAATGTTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTGAAACCAGTATTTAAGCTTTAAATG
ACAGTAATATTGGCATAGAAAAAAGTAGCAAATGTTTACTGTATCAATTTCTAATGTTTACTATATAGAATTTCCTGTAATATATTTATA
TACTTTTTCATGAAAATGGAGTTATCAGTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATTATCTCACTTTGTAAATAAAAACAC
ACCTTAAAACATGAACAAGCC

>2666_2666_15_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000544085_PTPN13_chr4_87666119_ENST00000427191_length(amino acids)=2280AA_BP=641
MNYGSPVKQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQ
LSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNW
LTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKP
VKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTP
EHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAED
KQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPA
KPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHM
REAKKMKQKAELMKKKITLQNTSDGIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRGFNMGRA
ISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWEEKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTV
AELVGKPSHQMSRSDAESLAGVTKLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLDVLHKRWSIVSSPEREITLVNLKKDAKYGLG
FQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNE
MKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQVNGFFASHLGDQTWQESQHGSPSPS
VISKATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKND
NSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSPTSKEHVPVTP
QCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVIL
KVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKS
PSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPG
QSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSD
GRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINP
RSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSAPKSTKGNGSYSVGSCSQPALTPNDS
FSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLS
EERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFLTNDELAVLPVVK
VLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKE
EFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREV
RHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTED
QYIFCYQVILYVLTRLQAEEEQKQQPQLLK

--------------------------------------------------------------
>2666_2666_16_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000544085_PTPN13_chr4_87666119_ENST00000436978_length(transcript)=7667nt_BP=2061nt
GTAGTCCCGTAACATCGGGGCGCCGCGCCGGGACGCGTCCCCGCCCGGCTCCGCCAAATGGTGAGCGCGGCGCTGGCAGCAGGGCCCGCG
GGGTGAAGGCGCTCATGGACGGAAGACCCCTGGCTCTATAAGCTGAATTATGGCAGCCCAGTCAAGCAGACCTACTCCAATGAAGTCCAT
TGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCTTTGACAGCAATACATACGCCTAGTACAGCTGAGCCATCCAAG
TTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAAAACCAAAAACAATATGATACATCTTCAAAAACTCACTCAAAT
TCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGTGACAGTGAGGACAGTGACAGTGAACAAACCCCAGAGAAGCCT
CCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCAGTGGCATCAGCACATTCCAGCAGTGCAGAGTCAGAAAGCACC
AGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGTGACAGCGAAGAAAATGAGCCCCTAGAAACCCCAGCTCCGGAG
CCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACCAAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCCCCAGGAGC
ACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGTGCCACGAGTCAGGAGCATTCTGAATCCAAAGATCCTCCCCCT
AAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCCGGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGCAGGAGCCC
CCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAGGCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGCAGGGGGAA
AGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAAGACAAGCCCAAGGTGAAGACGAAAGGACGGCCCCGGGCCGCA
GCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAGAAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGGCTCTCTCA
GGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCACTTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCCCACCCCAC
AGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTCCAGGAGGACAGCCGCAAAGACAGACTCCCATTGCCTTTGAGA
GACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGCTTGATGGTGAAGATCACCCTAGACCTGCTCTCTCGGATACCC
CAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAGCCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGAGGAGCTCA
GACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGAGACTGTGATAACAAGAAAATCAGACTGGAGAAGGAAATCAAA
TCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACAAAGCCCTCCAGGCCCTCCTCACAGTCCTCAAAGAAGGAAATG
CTCCCCCCGCCACCCGTGTCCTCGTCCTCCCAGAAGCCAGCCAAGCCTGCACTTAAGAGGTCAAGGCGGGAAGCAGACACCTGTGGCCAG
GACCCTCCCAAAAGTGCCAGCAGTACCAAGAGCAACCACAAAGACTCTTCCATTCCCAAGCAGAGAAGAGTAGAGGGGAAGGGCTCCAGA
AGCTCCTCGGAGCACAAGGGTTCTTCCGGAGATACTGCAAATCCTTTTCCAGTGCCTTCTTTGCCAAATGGTAACTCTAAACCAGGGAAG
CCTCAAGTGAAGTTTGACAAACAACAAGCAGACCTTCACATGAGGGAGGCAAAAAAGATGAAGCAGAAAGCAGAGTTAATGAAAAAGAAA
ATCACATTGCAAAATACATCAGATGGAATAAAACATGGCTTCCAGACAGACAACAGTAAGATATGCCAGTACCTGCTGCACCTCTGCTCT
TACCAGCATAAGTTCCAGCTACAGATGAGAGCAAGACAGAGCAACCAAGATGCCCAAGATATTGAGAGAGCTTCGTTTAGGAGCCTGAAT
CTCCAAGCAGAGTCTGTTAGAGGATTTAATATGGGACGAGCAATCAGCACTGGCAGTCTGGCCAGCAGCACCCTCAACAAACTTGCTGTT
CGACCTTTATCAGTTCAAGCTGAGATTCTGAAGAGGCTATCCTGCTCAGAGCTGTCGCTTTACCAGCCATTGCAAAACAGTTCAAAAGAG
AAGAATGACAAAGCTTCATGGGAGGAAAAGCCTAGAGAGATGAGTAAATCATACCATGATCTCAGTCAGGCCTCTCTCTATCCACATCGG
AAAAATGTCATTGTTAACATGGAACCCCCACCACAAACCGTTGCAGAGTTGGTGGGAAAACCTTCTCACCAGATGTCAAGATCTGATGCA
GAATCTTTGGCAGGAGTGACAAAACTTAATAATTCAAAGTCTGTTGCGAGTTTAAATAGAAGTCCTGAAAGGAGGAAACATGAATCAGAC
TCCTCATCCATTGAAGACCCTGGGCAAGCATATGTTCTAGGAATGACTATGCATAGTTCTGGAAACTCTTCATCCCAAGTACCCTTAAAA
GAAAATGATGTGCTACACAAAAGATGGAGCATAGTATCTTCACCAGAAAGGGAGATCACCTTAGTGAACCTGAAAAAAGATGCAAAGTAT
GGCTTGGGATTTCAAATTATTGGTGGGGAGAAGATGGGAAGACTGGACCTAGGCATATTTATCAGTTCAGTTGCCCCTGGAGGACCAGCT
GACTTGGATGGATGCTTGAAGCCAGGAGACCGTTTGATATCTGTGAATAGTGTGAGTCTGGAGGGAGTCAGCCACCATGCTGCAATTGAA
ATTTTGCAAAATGCACCTGAAGATGTGACACTTGTTATCTCTCAGCCAAAAGAAAAGATATCCAAAGTGCCTTCTACTCCTGTGCATCTC
ACCAATGAGATGAAAAACTACATGAAGAAATCTTCCTACATGCAAGACAGTGCTATAGATTCTTCTTCCAAGGATCACCACTGGTCACGT
GGTACCCTGAGGCACATCTCGGAGAACTCCTTTGGGCCATCTGGGGGCCTGCGGGAAGGAAGCCTGAGTTCTCAAGATTCCAGGACTGAG
AGTGCCAGCTTGTCTCAAAGCCAGGTCAATGGTTTCTTTGCCAGCCATTTAGGTGACCAAACCTGGCAGGAATCACAGCATGGCAGCCCT
TCCCCATCTGTAATATCCAAAGCCACCGAGAAAGAGACTTTCACTGATAGTAACCAAAGCAAAACTAAAAAGCCAGGCATTTCTGATGTA
ACTGATTACTCAGACCGTGGAGATTCAGACATGGATGAAGCCACTTACTCCAGCAGTCAGGATCATCAAACACCAAAACAGGAATCTTCC
TCTTCAGTGAATACATCCAACAAGATGAATTTTAAAACTTTTTCTTCATCACCTCCTAAGCCTGGAGATATCTTTGAGGTTGAACTGGCT
AAAAATGATAACAGCTTGGGGATAAGTGTCACGGTACTGTTTGACAAGGGAGGTGTGAATACGAGTGTCAGACATGGTGGCATTTATGTG
AAAGCTGTTATTCCCCAGGGAGCAGCAGAGTCTGATGGTAGAATTCACAAAGGTGATCGCGTCCTAGCTGTCAATGGAGTTAGTCTAGAA
GGAGCCACCCATAAGCAAGCTGTGGAAACACTGAGAAATACAGGACAGGTGGTTCATCTGTTATTAGAAAAGGGACAATCTCCAACATCT
AAAGAACATGTCCCGGTAACCCCACAGTGTACCCTTTCAGATCAGAATGCCCAAGGTCAAGGCCCAGAAAAAGTGAAGAAAACAACTCAG
GTCAAAGACTACAGCTTTGTCACTGAAGAAAATACATTTGAGGTAAAATTATTTAAAAATAGCTCAGGTCTAGGATTCAGTTTTTCTCGA
GAAGATAATCTTATACCGGAGCAAATTAATGCCAGCATAGTAAGGGTTAAAAAGCTCTTTCCTGGACAGCCAGCAGCAGAAAGTGGAAAA
ATTGATGTAGGAGATGTTATCTTGAAAGTGAATGGAGCCTCTTTGAAAGGACTATCTCAGCAGGAAGTCATATCTGCTCTCAGGGGAACT
GCTCCAGAAGTATTCTTGCTTCTCTGCAGACCTCCACCTGGTGTGCTACCGGAAATTGATACTGCGCTTTTGACCCCACTTCAGTCTCCA
GCACAAGTACTTCCAAACAGCAGTAAAGACTCTTCTCAGCCATCATGTGTGGAGCAAAGCACCAGCTCAGATGAAAATGAAATGTCAGAC
AAAAGCAAAAAACAGTGCAAGTCCCCATCCAGAAGAGACAGTTACAGTGACAGCAGTGGGAGTGGAGAAGATGACTTAGTGACAGCTCCA
GCAAACATATCAAATTCGACCTGGAGTTCAGCTTTGCATCAGACTCTAAGCAACATGGTATCACAGGCACAGAGTCATCATGAAGCACCC
AAGAGTCAAGAAGATACCATTTGTACCATGTTTTACTATCCTCAGAAAATTCCCAATAAACCAGAGTTTGAGGACAGTAATCCTTCCCCT
CTACCACCGGATATGGCTCCTGGGCAGAGTTATCAACCCCAATCAGAATCTGCTTCCTCTAGTTCGATGGATAAGTATCATATACATCAC
ATTTCTGAACCAACTAGACAAGAAAACTGGACACCTTTGAAAAATGACTTGGAAAATCACCTTGAAGACTTTGAACTGGAAGTAGAACTC
CTCATTACCCTAATTAAATCAGAAAAAGGAAGCCTGGGTTTTACAGTAACCAAAGGCAATCAGAGAATTGGTTGTTATGTTCATGATGTC
ATACAGGATCCAGCCAAAAGTGATGGAAGGCTAAAACCTGGGGACCGGCTCATAAAGGTTAATGATACAGATGTTACTAATATGACTCAT
ACAGATGCAGTTAATCTGCTCCGGGCTGCATCCAAAACAGTCAGATTAGTTATTGGACGAGTTCTAGAATTACCCAGAATACCAATGTTG
CCTCATTTGCTACCGGACATAACACTAACGTGCAACAAAGAGGAGTTGGGTTTTTCCTTATGTGGAGGTCATGACAGCCTTTATCAAGTG
GTATATATTAGTGATATTAATCCAAGGTCCGTCGCAGCCATTGAGGGTAATCTCCAGCTATTAGATGTCATCCATTATGTGAACGGAGTC
AGCACACAAGGAATGACCTTGGAGGAAGTTAACAGAGCATTAGACATGTCACTTCCTTCATTGGTATTGAAAGCAACAAGAAATGATCTT
CCAGTGGTCCCCAGCTCAAAGAGGTCTGCTGTTTCAGCTCCAAAGTCAACCAAAGGCAATGGTTCCTACAGTGTGGGGTCTTGCAGCCAG
CCTGCCCTCACTCCTAATGATTCATTCTCCACGGTTGCTGGGGAAGAAATAAATGAAATATCGTACCCCAAAGGAAAATGTTCTACTTAT
CAGATAAAGGGATCACCAAACTTGACTCTGCCCAAAGAATCTTATATACAAGAAGATGACATTTATGATGATTCCCAAGAAGCTGAAGTT
ATCCAGTCTCTGCTGGATGTTGTGGATGAGGAAGCCCAGAATCTTTTAAACGAAAATAATGCAGCAGGATACTCCTGTGGTCCAGGTACA
TTAAAGATGAATGGGAAGTTATCAGAAGAGAGAACAGAAGATACAGACTGCGATGGTTCACCTTTACCTGAGTATTTTACTGAGGCCACC
AAAATGAATGGCTGTGAAGAATATTGTGAAGAAAAAGTAAAAAGTGAAAGCTTAATTCAGAAGCCACAAGAAAAGAAGACTGATGATGAT
GAAATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCATGAAGATTCTGATAAAGATCATTCCTTTCTGACAAACGATGAG
CTCGCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACGGGTGCCAACTTAAAATCAGTCATTCGAGTCCTGCGGGGTTTG
CTAGATCAAGGAATTCCTTCTAAGGAGCTGGAGAATCTTCAAGAATTAAAACCTTTGGATCAGTGTCTAATTGGGCAAACTAAGGAAAAC
AGAAGGAAGAACAGATATAAAAATATACTTCCCTATGATGCTACAAGAGTGCCTCTTGGAGATGAAGGTGGCTATATCAATGCCAGCTTC
ATTAAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAAGGACCACTGCCTACAACTGTTGGAGACTTCTGGCAGATGATT
TGGGAGCAAAAATCCACAGTGATAGCCATGATGACTCAAGAAGTAGAAGGAGAAAAAATCAAATGCCAGCGCTATTGGCCCAACATCCTA
GGCAAAACAACAATGGTCAGCAACAGACTTCGACTGGCTCTTGTGAGAATGCAGCAGCTGAAGGGCTTTGTGGTGAGGGCAATGACCCTT
GAAGATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTCACTGCCTGGCCAGACCATGATACACCTTCTCAACCAGATGAT
CTGCTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCAATCATTACGCACTGCAGTGCTGGCATTGGACGTTCAGGGACC
CTGATTTGCATAGATGTGGTTCTGGGATTAATCAGTCAGGATCTTGATTTTGACATCTCTGATTTGGTGCGCTGCATGAGACTACAAAGA
CACGGAATGGTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTCATCCTTTATGTCCTGACACGTCTTCAAGCAGAAGAAGAGCAA
AAACAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATGCATTTCCATTTCTCTCCTTAACCTCCAGCAGACTCCTGCTCT
CTATCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGCATGTTCTCCTCTATCTTAGAGGGGTATTCTTCTTGAAAATAAAAA
ATATTGAAATGCTGTATTTTTACAGCTACTTTAACCTATGATAATTATTTACAAAATTTTAACACTAACCAAACAATGCAGATCTTAGGG
ATGATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACATGGTGAGTCTATTTTTAATGCACCAATCTTGTTTATAGCAAAA
ATGTTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTGAAACCAGTATTTAAGCTTTAAATGACAGTAATATTGGCATAG
AAAAAAGTAGCAAATGTTTACTGTATCAATTTCTAATGTTTACTATATAGAATTTCCTGTAATATATTTATATACTTTTTCATGAAAATG
GAGTTATCAGTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATTATCTCACTTTGTAAATAAAAACACACCTTAAAACATGAACAA
GCCAAAACTGTGTGCAG

>2666_2666_16_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000544085_PTPN13_chr4_87666119_ENST00000436978_length(amino acids)=2304AA_BP=641
MNYGSPVKQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQ
LSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNW
LTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKP
VKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTP
EHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAED
KQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPA
KPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHM
REAKKMKQKAELMKKKITLQNTSDGIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRGFNMGRA
ISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWEEKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTV
AELVGKPSHQMSRSDAESLAGVTKLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKRWSIVSS
PEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVIS
QPKEKISKVPSTPVHLTNEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQVNGFFA
SHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTF
SSSPPKPGDIFEVELAKNDNSLGISVTVLFDKGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNT
GQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIV
RVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQP
SCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYP
QKIPNKPEFEDSNPSPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLGF
TVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKE
ELGFSLCGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSAP
KSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQN
LLNENNAAGYSCGPGTLKMNGKLSEERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERT
NHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDA
TRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLAL
VRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQD
LDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK

--------------------------------------------------------------
>2666_2666_17_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000544085_PTPN13_chr4_87718027_ENST00000427191_length(transcript)=3780nt_BP=2061nt
GTAGTCCCGTAACATCGGGGCGCCGCGCCGGGACGCGTCCCCGCCCGGCTCCGCCAAATGGTGAGCGCGGCGCTGGCAGCAGGGCCCGCG
GGGTGAAGGCGCTCATGGACGGAAGACCCCTGGCTCTATAAGCTGAATTATGGCAGCCCAGTCAAGCAGACCTACTCCAATGAAGTCCAT
TGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCTTTGACAGCAATACATACGCCTAGTACAGCTGAGCCATCCAAG
TTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAAAACCAAAAACAATATGATACATCTTCAAAAACTCACTCAAAT
TCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGTGACAGTGAGGACAGTGACAGTGAACAAACCCCAGAGAAGCCT
CCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCAGTGGCATCAGCACATTCCAGCAGTGCAGAGTCAGAAAGCACC
AGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGTGACAGCGAAGAAAATGAGCCCCTAGAAACCCCAGCTCCGGAG
CCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACCAAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCCCCAGGAGC
ACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGTGCCACGAGTCAGGAGCATTCTGAATCCAAAGATCCTCCCCCT
AAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCCGGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGCAGGAGCCC
CCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAGGCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGCAGGGGGAA
AGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAAGACAAGCCCAAGGTGAAGACGAAAGGACGGCCCCGGGCCGCA
GCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAGAAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGGCTCTCTCA
GGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCACTTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCCCACCCCAC
AGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTCCAGGAGGACAGCCGCAAAGACAGACTCCCATTGCCTTTGAGA
GACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGCTTGATGGTGAAGATCACCCTAGACCTGCTCTCTCGGATACCC
CAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAGCCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGAGGAGCTCA
GACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGAGACTGTGATAACAAGAAAATCAGACTGGAGAAGGAAATCAAA
TCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACAAAGCCCTCCAGGCCCTCCTCACAGTCCTCAAAGAAGGAAATG
CTCCCCCCGCCACCCGTGTCCTCGTCCTCCCAGAAGCCAGCCAAGCCTGCACTTAAGAGGTCAAGGCGGGAAGCAGACACCTGTGGCCAG
GACCCTCCCAAAAGTGCCAGCAGTACCAAGAGCAACCACAAAGACTCTTCCATTCCCAAGCAGAGAAGAGTAGAGGGGAAGGGCTCCAGA
AGCTCCTCGGAGCACAAGGGTTCTTCCGGAGATACTGCAAATCCTTTTCCAGTGCCTTCTTTGCCAAATGGTAACTCTAAACCAGGGAAG
CCTCAAGTGAAGTTTGACAAACAACAAGCAGACCTTCACATGAGGGAGGCAAAAAAGATGAAGCAGAAAGCAGAGTTAATGGCCACCAAA
ATGAATGGCTGTGAAGAATATTGTGAAGAAAAAGTAAAAAGTGAAAGCTTAATTCAGAAGCCACAAGAAAAGAAGACTGATGATGATGAA
ATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCATGAAGATTCTGATAAAGATCATTCCTTTCTGACAAACGATGAGCTC
GCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACGGGTGCCAACTTAAAATCAGTCATTCGAGTCCTGCGGGGTTTGCTA
GATCAAGGAATTCCTTCTAAGGAGCTGGAGAATCTTCAAGAATTAAAACCTTTGGATCAGTGTCTAATTGGGCAAACTAAGGAAAACAGA
AGGAAGAACAGATATAAAAATATACTTCCCTATGATGCTACAAGAGTGCCTCTTGGAGATGAAGGTGGCTATATCAATGCCAGCTTCATT
AAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAAGGACCACTGCCTACAACTGTTGGAGACTTCTGGCAGATGATTTGG
GAGCAAAAATCCACAGTGATAGCCATGATGACTCAAGAAGTAGAAGGAGAAAAAATCAAATGCCAGCGCTATTGGCCCAACATCCTAGGC
AAAACAACAATGGTCAGCAACAGACTTCGACTGGCTCTTGTGAGAATGCAGCAGCTGAAGGGCTTTGTGGTGAGGGCAATGACCCTTGAA
GATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTCACTGCCTGGCCAGACCATGATACACCTTCTCAACCAGATGATCTG
CTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCAATCATTACGCACTGCAGTGCTGGCATTGGACGTTCAGGGACCCTG
ATTTGCATAGATGTGGTTCTGGGATTAATCAGTCAGGATCTTGATTTTGACATCTCTGATTTGGTGCGCTGCATGAGACTACAAAGACAC
GGAATGGTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTCATCCTTTATGTCCTGACACGTCTTCAAGCAGAAGAAGAGCAAAAA
CAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATGCATTTCCATTTCTCTCCTTAACCTCCAGCAGACTCCTGCTCTCTA
TCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGCATGTTCTCCTCTATCTTAGAGGGGTATTCTTCTTGAAAATAAAAAATA
TTGAAATGCTGTATTTTTACAGCTACTTTAACCTATGATAATTATTTACAAAATTTTAACACTAACCAAACAATGCAGATCTTAGGGATG
ATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACATGGTGAGTCTATTTTTAATGCACCAATCTTGTTTATAGCAAAAATG
TTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTGAAACCAGTATTTAAGCTTTAAATGACAGTAATATTGGCATAGAAA
AAAGTAGCAAATGTTTACTGTATCAATTTCTAATGTTTACTATATAGAATTTCCTGTAATATATTTATATACTTTTTCATGAAAATGGAG
TTATCAGTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATTATCTCACTTTGTAAATAAAAACACACCTTAAAACATGAACAAGCC

>2666_2666_17_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000544085_PTPN13_chr4_87718027_ENST00000427191_length(amino acids)=1013AA_BP=641
MNYGSPVKQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQ
LSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNW
LTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKP
VKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTP
EHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAED
KQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPA
KPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHM
REAKKMKQKAELMATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKY
TGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIAC
QGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLN
FTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQ
VILYVLTRLQAEEEQKQQPQLLK

--------------------------------------------------------------
>2666_2666_18_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000544085_PTPN13_chr4_87718027_ENST00000436978_length(transcript)=3794nt_BP=2061nt
GTAGTCCCGTAACATCGGGGCGCCGCGCCGGGACGCGTCCCCGCCCGGCTCCGCCAAATGGTGAGCGCGGCGCTGGCAGCAGGGCCCGCG
GGGTGAAGGCGCTCATGGACGGAAGACCCCTGGCTCTATAAGCTGAATTATGGCAGCCCAGTCAAGCAGACCTACTCCAATGAAGTCCAT
TGTGTTGAAGAGATTCTGAAGGAAATGACCCATTCATGGCCGCCTCCTTTGACAGCAATACATACGCCTAGTACAGCTGAGCCATCCAAG
TTTCCTTTCCCTACAAAGGACTCTCAGCATGTCAGTTCTGTAACCCAAAACCAAAAACAATATGATACATCTTCAAAAACTCACTCAAAT
TCTCAGCAAGGAACGTCATCCATGCTCGAAGACGACCTTCAGCTCAGTGACAGTGAGGACAGTGACAGTGAACAAACCCCAGAGAAGCCT
CCCTCCTCATCTGCACCTCCAAGTGCTCCACAGTCCCTTCCAGAACCAGTGGCATCAGCACATTCCAGCAGTGCAGAGTCAGAAAGCACC
AGTGACTCAGACAGTTCCTCAGACTCAGAGAGCGAGAGCAGTTCAAGTGACAGCGAAGAAAATGAGCCCCTAGAAACCCCAGCTCCGGAG
CCTGAGCCTCCAACAACAAACAAATGGCAGCTGGACAACTGGCTGACCAAAGTCAGCCAGCCAGCTGCGCCACCAGAGGGCCCCAGGAGC
ACAGAGCCCCCACGGCGGCACCCAGAGAGTAAGGGCAGCAGCGACAGTGCCACGAGTCAGGAGCATTCTGAATCCAAAGATCCTCCCCCT
AAAAGCTCCAGCAAAGCCCCCCGGGCCCCACCCGAAGCCCCCCACCCCGGAAAGAGGAGCTGTCAGAAGTCTCCGGCACAGCAGGAGCCC
CCACAAAGGCAAACCGTTGGAACCAAACAACCCAAAAAACCTGTCAAGGCCTCTGCCCGGGCAGGTTCACGGACCAGCCTGCAGGGGGAA
AGGGAGCCAGGGCTTCTTCCCTATGGCTCCCGAGACCAGACTTCCAAAGACAAGCCCAAGGTGAAGACGAAAGGACGGCCCCGGGCCGCA
GCAAGCAACGAACCCAAGCCAGCAGTGCCCCCCTCCAGTGAGAAGAAGAAGCACAAGAGCTCCCTCCCTGCCCCCTCTAAGGCTCTCTCA
GGCCCAGAACCCGCGAAGGACAATGTGGAGGACAGGACCCCTGAGCACTTTGCTCTTGTTCCCCTGACTGAGAGCCAGGGCCCACCCCAC
AGTGGCAGCGGCAGCAGGACTAGTGGCTGCCGCCAAGCCGTGGTGGTCCAGGAGGACAGCCGCAAAGACAGACTCCCATTGCCTTTGAGA
GACACCAAGCTGCTCTCACCGCTCAGGGACACTCCTCCCCCACAAAGCTTGATGGTGAAGATCACCCTAGACCTGCTCTCTCGGATACCC
CAGCCTCCCGGGAAGGGGAGCCGCCAGAGGAAAGCAGAAGATAAACAGCCGCCCGCAGGGAAGAAGCACAGCTCTGAGAAGAGGAGCTCA
GACAGCTCAAGCAAGTTGGCCAAAAAGAGAAAGGGTGAAGCAGAAAGAGACTGTGATAACAAGAAAATCAGACTGGAGAAGGAAATCAAA
TCACAGTCATCTTCATCTTCATCCTCCCACAAAGAATCTTCTAAAACAAAGCCCTCCAGGCCCTCCTCACAGTCCTCAAAGAAGGAAATG
CTCCCCCCGCCACCCGTGTCCTCGTCCTCCCAGAAGCCAGCCAAGCCTGCACTTAAGAGGTCAAGGCGGGAAGCAGACACCTGTGGCCAG
GACCCTCCCAAAAGTGCCAGCAGTACCAAGAGCAACCACAAAGACTCTTCCATTCCCAAGCAGAGAAGAGTAGAGGGGAAGGGCTCCAGA
AGCTCCTCGGAGCACAAGGGTTCTTCCGGAGATACTGCAAATCCTTTTCCAGTGCCTTCTTTGCCAAATGGTAACTCTAAACCAGGGAAG
CCTCAAGTGAAGTTTGACAAACAACAAGCAGACCTTCACATGAGGGAGGCAAAAAAGATGAAGCAGAAAGCAGAGTTAATGGCCACCAAA
ATGAATGGCTGTGAAGAATATTGTGAAGAAAAAGTAAAAAGTGAAAGCTTAATTCAGAAGCCACAAGAAAAGAAGACTGATGATGATGAA
ATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCATGAAGATTCTGATAAAGATCATTCCTTTCTGACAAACGATGAGCTC
GCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACGGGTGCCAACTTAAAATCAGTCATTCGAGTCCTGCGGGGTTTGCTA
GATCAAGGAATTCCTTCTAAGGAGCTGGAGAATCTTCAAGAATTAAAACCTTTGGATCAGTGTCTAATTGGGCAAACTAAGGAAAACAGA
AGGAAGAACAGATATAAAAATATACTTCCCTATGATGCTACAAGAGTGCCTCTTGGAGATGAAGGTGGCTATATCAATGCCAGCTTCATT
AAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAAGGACCACTGCCTACAACTGTTGGAGACTTCTGGCAGATGATTTGG
GAGCAAAAATCCACAGTGATAGCCATGATGACTCAAGAAGTAGAAGGAGAAAAAATCAAATGCCAGCGCTATTGGCCCAACATCCTAGGC
AAAACAACAATGGTCAGCAACAGACTTCGACTGGCTCTTGTGAGAATGCAGCAGCTGAAGGGCTTTGTGGTGAGGGCAATGACCCTTGAA
GATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTCACTGCCTGGCCAGACCATGATACACCTTCTCAACCAGATGATCTG
CTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCAATCATTACGCACTGCAGTGCTGGCATTGGACGTTCAGGGACCCTG
ATTTGCATAGATGTGGTTCTGGGATTAATCAGTCAGGATCTTGATTTTGACATCTCTGATTTGGTGCGCTGCATGAGACTACAAAGACAC
GGAATGGTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTCATCCTTTATGTCCTGACACGTCTTCAAGCAGAAGAAGAGCAAAAA
CAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATGCATTTCCATTTCTCTCCTTAACCTCCAGCAGACTCCTGCTCTCTA
TCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGCATGTTCTCCTCTATCTTAGAGGGGTATTCTTCTTGAAAATAAAAAATA
TTGAAATGCTGTATTTTTACAGCTACTTTAACCTATGATAATTATTTACAAAATTTTAACACTAACCAAACAATGCAGATCTTAGGGATG
ATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACATGGTGAGTCTATTTTTAATGCACCAATCTTGTTTATAGCAAAAATG
TTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTGAAACCAGTATTTAAGCTTTAAATGACAGTAATATTGGCATAGAAA
AAAGTAGCAAATGTTTACTGTATCAATTTCTAATGTTTACTATATAGAATTTCCTGTAATATATTTATATACTTTTTCATGAAAATGGAG
TTATCAGTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATTATCTCACTTTGTAAATAAAAACACACCTTAAAACATGAACAAGCC
AAAACTGTGTGCAG

>2666_2666_18_AFF1-PTPN13_AFF1_chr4_88048855_ENST00000544085_PTPN13_chr4_87718027_ENST00000436978_length(amino acids)=1013AA_BP=641
MNYGSPVKQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQ
LSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNW
LTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKP
VKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTP
EHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAED
KQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPA
KPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHM
REAKKMKQKAELMATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKY
TGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIAC
QGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLN
FTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQ
VILYVLTRLQAEEEQKQQPQLLK

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Fusion Gene PPI Analysis for AFF1-PTPN13

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for AFF1-PTPN13

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for AFF1-PTPN13

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source

Fusion Gene Studies in Kim Lab

Fusion gene:AFF1-PTPN13 (FusionGDB2 ID:HG4299TG5783)

Fusion Gene Summary for AFF1-PTPN13

Fusion Gene ORF analysis for AFF1-PTPN13

Fusion Genomic Features for AFF1-PTPN13

Fusion Protein Features for AFF1-PTPN13

Fusion Gene Sequence for AFF1-PTPN13

Fusion Gene PPI Analysis for AFF1-PTPN13

Related Drugs for AFF1-PTPN13

Related Diseases for AFF1-PTPN13

Fusion Gene Studies
in Kim Lab