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in Kim Lab

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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GALNTL6-BARD1 (FusionGDB2 ID:HG442117TG580)

Fusion Gene Summary for GALNTL6-BARD1

check button Fusion gene summary
Fusion gene informationFusion gene name: GALNTL6-BARD1
Fusion gene ID: hg442117tg580
HgeneTgene
Gene symbol

GALNTL6

BARD1

Gene ID

442117

580

Gene namepolypeptide N-acetylgalactosaminyltransferase like 6BRCA1 associated RING domain 1
SynonymsGALNACT20|GALNT17|GalNAc-T6L-
Cytomap('GALNTL6')('BARD1')

4q34.1

2q35

Type of geneprotein-codingprotein-coding
Descriptionpolypeptide N-acetylgalactosaminyltransferase-like 6GaNTase 17GalNAc transferase 17UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 17UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 20UDP-N-acetyl-alpha-D-galaBRCA1-associated RING domain protein 1BRCA1-associated RING domain gene 1RING-type E3 ubiquitin transferase BARD1
Modification date2020031320200322
UniProtAcc.

Q99728

Ensembl transtripts involved in fusion geneENST00000506823, ENST00000511251, 
ENST00000457021, ENST00000508122, 
Fusion gene scores* DoF score7 X 7 X 2=984 X 4 X 3=48
# samples 74
** MAII scorelog2(7/98*10)=-0.485426827170242
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GALNTL6 [Title/Abstract] AND BARD1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGALNTL6(172735869)-BARD1(215634036), # samples:1
Anticipated loss of major functional domain due to fusion event.GALNTL6-BARD1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
GALNTL6-BARD1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
GALNTL6-BARD1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
GALNTL6-BARD1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneGALNTL6

GO:0018243

protein O-linked glycosylation via threonine

22186971

TgeneBARD1

GO:0046826

negative regulation of protein export from nucleus

15265711

TgeneBARD1

GO:0085020

protein K6-linked ubiquitination

12890688|20351172


check buttonFusion gene breakpoints across GALNTL6 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across BARD1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-FP-8209-01AGALNTL6chr4

172735869

+BARD1chr2

215634036

-


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Fusion Gene ORF analysis for GALNTL6-BARD1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000506823ENST00000432456GALNTL6chr4

172735869

+BARD1chr2

215634036

-
5CDS-intronENST00000506823ENST00000471787GALNTL6chr4

172735869

+BARD1chr2

215634036

-
5CDS-intronENST00000511251ENST00000432456GALNTL6chr4

172735869

+BARD1chr2

215634036

-
5CDS-intronENST00000511251ENST00000471787GALNTL6chr4

172735869

+BARD1chr2

215634036

-
In-frameENST00000506823ENST00000260947GALNTL6chr4

172735869

+BARD1chr2

215634036

-
In-frameENST00000506823ENST00000449967GALNTL6chr4

172735869

+BARD1chr2

215634036

-
In-frameENST00000511251ENST00000260947GALNTL6chr4

172735869

+BARD1chr2

215634036

-
In-frameENST00000511251ENST00000449967GALNTL6chr4

172735869

+BARD1chr2

215634036

-
intron-3CDSENST00000457021ENST00000260947GALNTL6chr4

172735869

+BARD1chr2

215634036

-
intron-3CDSENST00000457021ENST00000449967GALNTL6chr4

172735869

+BARD1chr2

215634036

-
intron-3CDSENST00000508122ENST00000260947GALNTL6chr4

172735869

+BARD1chr2

215634036

-
intron-3CDSENST00000508122ENST00000449967GALNTL6chr4

172735869

+BARD1chr2

215634036

-
intron-intronENST00000457021ENST00000432456GALNTL6chr4

172735869

+BARD1chr2

215634036

-
intron-intronENST00000457021ENST00000471787GALNTL6chr4

172735869

+BARD1chr2

215634036

-
intron-intronENST00000508122ENST00000432456GALNTL6chr4

172735869

+BARD1chr2

215634036

-
intron-intronENST00000508122ENST00000471787GALNTL6chr4

172735869

+BARD1chr2

215634036

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000506823GALNTL6chr4172735869+ENST00000260947BARD1chr2215634036-48457952791814511
ENST00000506823GALNTL6chr4172735869+ENST00000449967BARD1chr2215634036-17837952791616445
ENST00000511251GALNTL6chr4172735869+ENST00000260947BARD1chr2215634036-6648259826763617313
ENST00000511251GALNTL6chr4172735869+ENST00000449967BARD1chr2215634036-3586259826763419247

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000506823ENST00000260947GALNTL6chr4172735869+BARD1chr2215634036-0.0001411120.99985886
ENST00000506823ENST00000449967GALNTL6chr4172735869+BARD1chr2215634036-0.0043242240.99567574
ENST00000511251ENST00000260947GALNTL6chr4172735869+BARD1chr2215634036-0.0032879190.9967121
ENST00000511251ENST00000449967GALNTL6chr4172735869+BARD1chr2215634036-0.0678949950.93210506

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Fusion Genomic Features for GALNTL6-BARD1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for GALNTL6-BARD1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:172735869/chr2:215634036)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.BARD1

Q99728

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage. {ECO:0000269|PubMed:12890688, ECO:0000269|PubMed:14976165, ECO:0000269|PubMed:20351172}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGALNTL6chr4:172735869chr2:215634036ENST00000506823+2131_746602.0Topological domainCytoplasmic
HgeneGALNTL6chr4:172735869chr2:215634036ENST00000506823+2138_2846602.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneBARD1chr4:172735869chr2:215634036ENST00000260947311542_545438778.0Compositional biasNote=Poly-Leu
TgeneBARD1chr4:172735869chr2:215634036ENST00000260947311560_653438778.0DomainBRCT 1
TgeneBARD1chr4:172735869chr2:215634036ENST00000260947311667_777438778.0DomainBRCT 2
TgeneBARD1chr4:172735869chr2:215634036ENST00000260947311554_558438778.0RegionNote=Flexible linker
TgeneBARD1chr4:172735869chr2:215634036ENST00000260947311460_492438778.0RepeatNote=ANK 2
TgeneBARD1chr4:172735869chr2:215634036ENST00000260947311493_525438778.0RepeatNote=ANK 3
TgeneBARD1chr4:172735869chr2:215634036ENST00000260947311526_546438778.0RepeatNote=ANK 4%3B degenerate

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGALNTL6chr4:172735869chr2:215634036ENST00000506823+213453_58546602.0DomainRicin B-type lectin
HgeneGALNTL6chr4:172735869chr2:215634036ENST00000508122+112453_5850585.0DomainRicin B-type lectin
HgeneGALNTL6chr4:172735869chr2:215634036ENST00000506823+213139_24846602.0RegionNote=Catalytic subdomain A
HgeneGALNTL6chr4:172735869chr2:215634036ENST00000506823+213306_36846602.0RegionNote=Catalytic subdomain B
HgeneGALNTL6chr4:172735869chr2:215634036ENST00000508122+112139_2480585.0RegionNote=Catalytic subdomain A
HgeneGALNTL6chr4:172735869chr2:215634036ENST00000508122+112306_3680585.0RegionNote=Catalytic subdomain B
HgeneGALNTL6chr4:172735869chr2:215634036ENST00000506823+21329_60146602.0Topological domainLumenal
HgeneGALNTL6chr4:172735869chr2:215634036ENST00000508122+1121_70585.0Topological domainCytoplasmic
HgeneGALNTL6chr4:172735869chr2:215634036ENST00000508122+11229_6010585.0Topological domainLumenal
HgeneGALNTL6chr4:172735869chr2:215634036ENST00000508122+1128_280585.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneBARD1chr4:172735869chr2:215634036ENST00000260947311400_403438778.0Compositional biasNote=Poly-Ser
TgeneBARD1chr4:172735869chr2:215634036ENST00000260947311427_459438778.0RepeatNote=ANK 1
TgeneBARD1chr4:172735869chr2:215634036ENST0000026094731150_87438778.0Zinc fingerRING-type


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Fusion Gene Sequence for GALNTL6-BARD1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>32323_32323_1_GALNTL6-BARD1_GALNTL6_chr4_172735869_ENST00000506823_BARD1_chr2_215634036_ENST00000260947_length(transcript)=4845nt_BP=795nt
GCAGCGCCCTCGTCCGCTTCCAAGCCCAGCACAGACTTCGGTTTCTCCGCCTCCATCCCCTTTACGAGAAGAGGAGATCAAAAAATATTG
CCCTTTAGGTGCTCGTGATGGTCCTGTGGGTTCGTTCAGTTGCCAGAAAAGAATGGTAACATGAACAGCGGAGCGTGAGAGCGTCACCGG
GGGAAGGGACGAGATTGATGGGCAGAGCGCTCACTTCTCAGAGGATCGCATTCCGAGGACCGCGCGAGGAAGGGACGTCGCGGCGCCACC
ACTTCCTGGCTGGACTCCGCTGACATCTGTAGCCTCCTTTCCACCAGGTTCCCGGGGCTCCCAGCCGCTGCCTGCAGAGGAGCGTGTAGA
CAGCGCGCGAGGGTCCGGCACTTCGTGGACCTCCATCCGAACCGGAGTTCTGCCCGGATCCCGAGTCCCTGGATCCCGGTGGAGCCCGCC
GGCAAGCTGGCTCCGGAGGGAGTTGAACTTGAGTTCAGATGGCCAACTCCCTCTGAATCCTGCAGATTGGTGCTGAGCACGCAACAAAAG
TTTGTAGCTTCTCAGTTTCTGGTGCTTCGCAGGGGAGAGGAAAGGAATTTGACATTAAACACAAGAAGCAGTCAGGGAGCCATCTCCTTT
AACTTTTCTTCTCTGTTACCATTTGCAATGAAGAGGAAACAGAAGAGATTTCTGCAGATGACTTTGTTGTTCACGGTGGCTTTAATTTTC
CTGCCTAACGTTGGTCTCTGGTCTCTGTACAAGGATAAGCACCTGGTGAAGTCAGCGGAGCCCGGGGAGCAGCAGGGCGACATACCTTCT
GTTGAATACCTTTTACAAAATGGAAGTGATCCAAATGTTAAAGACCATGCTGGATGGACACCATTGCATGAAGCTTGCAATCATGGGCAC
CTGAAGGTAGTGGAATTATTGCTCCAGCATAAGGCATTGGTGAACACCACCGGGTATCAAAATGACTCACCACTTCACGATGCAGCCAAG
AATGGGCATGTGGATATAGTCAAGCTGTTACTTTCCTATGGAGCCTCCAGAAATGCTGTTAATATATTTGGTCTGCGGCCTGTCGATTAT
ACAGATGATGAAAGTATGAAATCGCTATTGCTGCTACCAGAGAAGAATGAATCATCCTCAGCTAGCCACTGCTCAGTAATGAACACTGGG
CAGCGTAGGGATGGACCTCTTGTACTTATAGGCAGTGGGCTGTCTTCAGAACAACAGAAAATGCTCAGTGAGCTTGCAGTAATTCTTAAG
GCTAAAAAATATACTGAGTTTGACAGTACAGTAACTCATGTTGTTGTTCCTGGTGATGCAGTTCAAAGTACCTTGAAGTGTATGCTTGGG
ATTCTCAATGGATGCTGGATTCTAAAATTTGAATGGGTAAAAGCATGTCTACGAAGAAAAGTATGTGAACAGGAAGAAAAGTATGAAATT
CCTGAAGGTCCACGCAGAAGCAGGCTCAACAGAGAACAGCTGTTGCCAAAGCTGTTTGATGGATGCTACTTCTATTTGTGGGGAACCTTC
AAACACCATCCAAAGGACAACCTTATTAAGCTCGTCACTGCAGGTGGGGGCCAGATCCTCAGTAGAAAGCCCAAGCCAGACAGTGACGTG
ACTCAGACCATCAATACAGTCGCATACCATGCGAGACCCGATTCTGATCAGCGCTTCTGCACACAGTATATCATCTATGAAGATTTGTGT
AATTATCACCCAGAGAGGGTTCGGCAGGGCAAAGTCTGGAAGGCTCCTTCGAGCTGGTTTATAGACTGTGTGATGTCCTTTGAGTTGCTT
CCTCTTGACAGCTGAATATTATACCAGATGAACATTTCAAATTGAATTTGCACGGTTTGTGAGAGCCCAGTCATTGTACTGTTTTTAATG
TTCACATTTTTACAAATAGGTAGAGTCATTCATATTTGTCTTTGAATCAAAAAAAAAAAAAAAGTCTAATGCCAGATTAGGAATTCATGT
TATGTTTACCATTTAGAAGCTGGGATTGCTTTTAAAGGTTTTTCTTTTTAAAATTGGCATGTTTTTGATTTATCATGTCTTTCTATTCAG
ATTATTGGGTATCAAAGATTAATGAGGACACCAGAATCTTGGTTAAATAGACAAGTGGTATCATTACTGTTTGAGTCTTTTAATATTCTC
CATACCTGCCACCAGTGAAAAAACTTGCCTTTTTTTTTTTTTTTTTTTTAGTAAACAGAATATTATCAAACAATTTATTTTGGCTTTATT
GAAAAAAGAGTATTTGGTCTAAATGTGCCACCATAGGTGTTAAATTCTCCTATCTGCAATTGTCTTTATCCTATATTGTGTTCATTTCTT
TTCTTAATAATTTACTTTGTTGTGTGTTTCTACACTTTCATCCCTGTTTTTTATCTTGTATATCATCAGGAAATTGTGATTTAATCATTA
ACATTGGTTTTTTTGTGTGTGTGGTAAAAATCAACACTAGGCTCATGGTACATATTTTTATTCTGTACATTTGCTTGTAACTATCAATTT
GTAACTCTGTTTATCTACTACATGTGTATATATACTTAGAGCATTTTCTCTAACACATTTTAATGTTAGTATTTTTTAAAAGGTCTGACC
AGTCTAGCAAATTGTCAGTCCAACGTCATTACTTTAAATTAAGAAGCAGTCTTCTTCTGGTAAACCTTGTTGGTATTTGTAAAATAATTT
TGAAGGTCTTAATTTCTTCCTTTGTAAAAGGAAAAGGTTTTTTTTAAAGTTTTTAGGTTGGCATGGAGGCAGAAGTTGGTGATTACTTGA
TTTACAACAGATTTTTTCCAGATCATACAAAAGGCCATACAGTAAGTATAGAAGTAGGTATGGGGAGGGCTTACTAATATCAAATAGGCA
AGGCCTTAGTGAGTGGGCAGGATACCACCTGAGAGTGGCCAGATGTGGGGAGGTTACTCTGCTCTGGGTGCTCTCATTCATGAATCGACA
AGGATACATTAGATTATTTTGAAACATTTTTTTAAGAAGCAGAATTCTTTAATAATTCCTTCCTAGACATTGAATATACTTATAAAATTA
AAGACTTGGGGAAGGAGACACTGAGAGACTTGCCAGTTTGGTTCCTCATGAACAAAAGAGGACAGTTTGATAACTACCAGAATAGAATAT
CCCTAGTTTTAAAATAGTGAGAATCTCTGAAGTTCATCAACATCTTAAGATGCACTTACTTGAAAGTTTGAGATTCTGTTTATCATTTGA
AAACACATTTTGCTTTAATTCTTTCTTTGACATGTTGTTTTTTCATATCAAGAAATATATGAACAAAATAATAACCTTTTGACCCTGACC
TTGCTGGGTGAATTAGCTCTGAAACACTCTCTACAACCAGTAATGCATTTGTCCCACATTTCATTCTGATAGAAAATGAACACCATAGCA
CCAAACAAAAATCCGAGGCGTTAGATAATGTCTGGATTAAATAATTTAAGACTCTCTAGGATTTTGGTTGTCATTTTTTATTTATAACAG
ACTTTAAGTCACTTTCTGTTGCCTCATAGGTCACATTTTAGACAGGTTTGTGTCTGTTCCTTGCATCTGAATTCCTGATTGTAAAGACAC
CTATGAGGTCTCTTAGTTTTTGTCATTCATTTTCTTGGTTTATCACCCCTCCCTTCTTTTTGTTGTTTTTCCCTGACTGTTAAGCAGTTT
CATCTTTGCTTTTGTTAAATATTTGACAGCAGTTAGTTTGTGTTAAGCTCTTGAAACTTGTGATTGTACTTTCTGTGTAGATATACATGT
AATTATTTTTTATTTTTCAATCATAGATTCAAGCTTCCTTCTTTTTTACCACAAATCATTAAAGTTATTTGTGTTTCCATATACCTGTGT
CTTGTATAAAATTGGCTTATTCTGTGCTGTTGAATGAGGCTCAACATGACTTGGTGAGGAAGTCTATTAACTAACAAAAGCTTATCTTTT
TTAACATAATGCTTTTTAATTAATTTTGAATAAAAATATTTCTAAAGTGTACTAGATACTTTATTACCTTAGATTATTCCGAATACAGTA
TAACTTTGATAGTTTGGAATAGTCATTAAGAAACAATTACACACTGATTGCTTTGTGTCTCTAAAAGTGAGAGGCTGGTAGCTTTTCCAC
ATTCTCATGGCTATTTTCTAGTTCTACTTGAATTTATAACTGTTTCCCTTTTTCCTTGACAGCTGCCACTTTGTAGCTATTTTTCTGTCT
CTGCTAATACTTTACCATATCTATCTCAATTGTTTTTTCTTTTGACTTGCTGAAAAATAGAAACCAGATGGGAAGTATATTAGCATTATG
ATTGAAATAAGGGTAAATGAGCAATGTGTGAAGGTTTTCACTGACTTCACCTAAAAGATAGTTTAGCTACTTGAATTTTAGTAAATAGAA
TTTTTCCTTTATTTCATCGGTCCCCCCACCTTTTTTTTTTTTTGCACCTGCCTTGTAAATTTAATAGTTAAGTGACCTCTGCCTAGAGGA
TGATATTTGGGGAGGTTTGATGTTTCCTGTGGGAATAAGACGATTCACAGGTGAGAGTGGGGCCACATTAGCTGTTATTGTTTCCATGGG
TCAGTGTGGAAAATGCATTAATCATATTCTAAACGTTCATGGGCCTCATTACAGTCACAATTGTCTATTCTGTTTCCTACCCTGAACACA
TTAAAATGGTAGGAACTAATGCTTGTCTTATTTAATTACTAAAAGCCACCATTTTCTTTGATAGATTGAGCTACAGATTGTAAACTTCAT

>32323_32323_1_GALNTL6-BARD1_GALNTL6_chr4_172735869_ENST00000506823_BARD1_chr2_215634036_ENST00000260947_length(amino acids)=511AA_BP=172
MDSADICSLLSTRFPGLPAAACRGACRQRARVRHFVDLHPNRSSARIPSPWIPVEPAGKLAPEGVELEFRWPTPSESCRLVLSTQQKFVA
SQFLVLRRGEERNLTLNTRSSQGAISFNFSSLLPFAMKRKQKRFLQMTLLFTVALIFLPNVGLWSLYKDKHLVKSAEPGEQQGDIPSVEY
LLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDD
ESMKSLLLLPEKNESSSASHCSVMNTGQRRDGPLVLIGSGLSSEQQKMLSELAVILKAKKYTEFDSTVTHVVVPGDAVQSTLKCMLGILN
GCWILKFEWVKACLRRKVCEQEEKYEIPEGPRRSRLNREQLLPKLFDGCYFYLWGTFKHHPKDNLIKLVTAGGGQILSRKPKPDSDVTQT

--------------------------------------------------------------
>32323_32323_2_GALNTL6-BARD1_GALNTL6_chr4_172735869_ENST00000506823_BARD1_chr2_215634036_ENST00000449967_length(transcript)=1783nt_BP=795nt
GCAGCGCCCTCGTCCGCTTCCAAGCCCAGCACAGACTTCGGTTTCTCCGCCTCCATCCCCTTTACGAGAAGAGGAGATCAAAAAATATTG
CCCTTTAGGTGCTCGTGATGGTCCTGTGGGTTCGTTCAGTTGCCAGAAAAGAATGGTAACATGAACAGCGGAGCGTGAGAGCGTCACCGG
GGGAAGGGACGAGATTGATGGGCAGAGCGCTCACTTCTCAGAGGATCGCATTCCGAGGACCGCGCGAGGAAGGGACGTCGCGGCGCCACC
ACTTCCTGGCTGGACTCCGCTGACATCTGTAGCCTCCTTTCCACCAGGTTCCCGGGGCTCCCAGCCGCTGCCTGCAGAGGAGCGTGTAGA
CAGCGCGCGAGGGTCCGGCACTTCGTGGACCTCCATCCGAACCGGAGTTCTGCCCGGATCCCGAGTCCCTGGATCCCGGTGGAGCCCGCC
GGCAAGCTGGCTCCGGAGGGAGTTGAACTTGAGTTCAGATGGCCAACTCCCTCTGAATCCTGCAGATTGGTGCTGAGCACGCAACAAAAG
TTTGTAGCTTCTCAGTTTCTGGTGCTTCGCAGGGGAGAGGAAAGGAATTTGACATTAAACACAAGAAGCAGTCAGGGAGCCATCTCCTTT
AACTTTTCTTCTCTGTTACCATTTGCAATGAAGAGGAAACAGAAGAGATTTCTGCAGATGACTTTGTTGTTCACGGTGGCTTTAATTTTC
CTGCCTAACGTTGGTCTCTGGTCTCTGTACAAGGATAAGCACCTGGTGAAGTCAGCGGAGCCCGGGGAGCAGCAGGGCGACATACCTTCT
GTTGAATACCTTTTACAAAATGGAAGTGATCCAAATGTTAAAGACCATGCTGGATGGACACCATTGCATGAAGCTTGCAATCATGGGCAC
CTGAAGGTAGTGGAATTATTGCTCCAGCATAAGGCATTGGTGAACACCACCGGGTATCAAAATGACTCACCACTTCACGATGCAGCCAAG
AATGGGCATGTGGATATAGTCAAGCTGTTACTTTCCTATGGAGCCTCCAGAAATGCTGTTAATATATTTGGTCTGCGGCCTGTCGATTAT
ACAGATGATGAAAGTATGAAATCGCTATTGCTGCTACCAGAGAAGAATGAATCATCCTCAGCTAGCCACTGCTCAGTAATGAACACTGGG
CAGCGTAGGGATGGACCTCTTGTACTTATAGGCAGTGGGCTGTCTTCAGAACAACAGAAAATGCTCAGTGAGCTTGCAGTAATTCTTAAG
GCTAAAAAATATACTGAGTTTGACAGTACAGTAACTCATGTTGTTGTTCCTGGTGATGCAGTTCAAAGTACCTTGAAGTGTATGCTTGGG
ATTCTCAATGGATGCTGGATTCTAAAATTTGAATGGGTAAAAGCATGTCTACGAAGAAAAGTATGTGAACAGGAAGAAAAGTATGAAATT
CCTGAAGGTCCACGCAGAAGCAGGCTCAACAGAGAACATTGCCAAAGCTGTTTGATGGATGCTACTTCTATTTGTGGGGAACCTTCAAAC
ACCATCCAAAGGACAACCTTATTAAGCTCGTCACTGCAGGTGGGGGCCAGATCCTCAGTAGAAAGCCCAAGCCAGACAGTGACGTGACTC
AGACCATCAATACAGTCGCATACCATGCGAGACCCGATTCTGATCAGCGCTTCTGCACACAGTATATCATCTATGAAGATTTGTGTAATT

>32323_32323_2_GALNTL6-BARD1_GALNTL6_chr4_172735869_ENST00000506823_BARD1_chr2_215634036_ENST00000449967_length(amino acids)=445AA_BP=172
MDSADICSLLSTRFPGLPAAACRGACRQRARVRHFVDLHPNRSSARIPSPWIPVEPAGKLAPEGVELEFRWPTPSESCRLVLSTQQKFVA
SQFLVLRRGEERNLTLNTRSSQGAISFNFSSLLPFAMKRKQKRFLQMTLLFTVALIFLPNVGLWSLYKDKHLVKSAEPGEQQGDIPSVEY
LLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDD
ESMKSLLLLPEKNESSSASHCSVMNTGQRRDGPLVLIGSGLSSEQQKMLSELAVILKAKKYTEFDSTVTHVVVPGDAVQSTLKCMLGILN

--------------------------------------------------------------
>32323_32323_3_GALNTL6-BARD1_GALNTL6_chr4_172735869_ENST00000511251_BARD1_chr2_215634036_ENST00000260947_length(transcript)=6648nt_BP=2598nt
TTTCTCAAGTGAGACACTAGAGAGAGTAGAAAGGGAGGAAGAGATAGGGCGAGAAGAAAAGGAGGGAGGGACAGAGATGAGGACGAGAAA
GAAGAAAAAAGGGAAAGAGAAAATACCGTCTGAAGTCCACAGGCTTATCTATCCCAAGCATGTCTACCCCACGCATGTGGGCATCATATC
CAGGTTGTAACAAAGAGGTGACCATGGCGTTTATTTTTGGCTCCAGACAGGCGGATTCAGCCTGCATTGCATGCATGCATGTCTGTCACC
TCATCTAAGTCCCCATTCCTTCCGGAGTTGTGAGCTCCAGATCCAAGAGTGCCCAGTGCACGGTGCTGGGCACGCTGTCCCTTGGCGAGG
CTGCCACAGGTTCCTGAGTGTGCGGTCAGGGGCGTTGGTGCATTGATACGTTAGGCGGAGGGAGGAGTACCATCTGCCAGAGTCTTATCT
CGAGTCCCACGTTTTCTGGCCATCGCGGAGGAGTGTGCGAGGACAGGTAGCCCTCGCAGTGACAAGGCGCGCGGAGTGCGGTCGTGCAAG
GCGGGGGAGGAGCGGGGTGGCCCTGCCGAATCTTAACCGGGGCCCCGGGTGTTTGCAGACCCAAATAAAGCCGCCTTGGGTCTCCACGGT
GTCCTCCAGAAGCTGCTGCCTGAGAACTCTGAGCCTCAGCTCTGTCTTGCTTCGGGATCCTCTTCCTCCTCCTTCCCCACCCCCTACCTG
GCCTGAACGGCGGAACGCGCGGCTCGGGGGATCCCCTCTCCCTGGGACCGGCCCTGTCCCGGGTCGCCTCCACCTCCCGCAGCCGCCGCG
CCCCGGCTCGCCGCGCTCCCGCCGGCACCATGGAGGAATTCCTGGGACAACCGCCTGCAGCCGGCGACTTTTCCCCAGGAATCTCTGGCC
TGGCGCCCTTTGGGTGAGATGACGGGGTGCTGGCATCCCTGTCGGTCCCAGATTACCCGGAAAAGCCCTGGCAGGTAAAGAGAGGACCCG
CGCAGGCTGGGAGCTCCCACTCCTCCTCCAGCGTCACGCTCGCCCTCCGCCGCTGCCTCGCGTCCGGGTCTGTTTATATAGCGTCTGGAG
GCCGGGAGGCATTGCCCACCCCCGCCAGGCGGCCCGCCCTCCCCTCCTGGGCTCCGGGCTGCCGCACGTGGCAGACACCAGCGACGTCTC
CGCGGAAGGCAGGCGCCGGGGAGTGGGGCGCGGGCGACCGTGTGCAGCCGCGGCGCATCTCCGCCTTCCGCTCCTCCTCGCAGCGCCCTC
GTCCGCTTCCAAGCCCAGCACAGACTTCGGTTTCTCCGCCTCCATCCCCTTTACGAGAAGAGGAGATCAAAAAATATTGCCCTTTAGGTG
CTCGTGATGGTCCTGTGGGTTCGTTCAGTTGCCAGAAAAGAATGGTAACATGAACAGCGGAGCGTGAGAGCGTCACCGGGGGAAGGGACG
AGATTGATGGGCAGAGCGCTCACTTCTCAGAGGATCGCATTCCGAGGACCGCGCGAGGAAGGGACGTCGCGGCGCCACCACTTCCTGGCT
GGACTCCGCTGACATCTGTAGCCTCCTTTCCACCAGGTTCCCGGGGCTCCCAGCCGCTGCCTGCAGAGGAGCGTGTAGACAGCGCGCGAG
GGTCCGGCACTTCGTGGACCTCCATCCGAACCGGAGTTCTGCCCGGATCCCGAGTCCCTGGATCCCGGTGGAGCCCGCCGGCAAGCTGGC
TCCGGAGGGAGTTGAACTTGAGTTCAGGTAAGTGCCACCCAGAGAAAGATCACACAAGGATTGGTAAGGCAGTGATCCTCGCGCGGGGAC
TCGAGAAAGCCGGTGTGGGATCGCCTTGGGTTTTCCCCCAAGTCTTGACAGAGCTGATTATTACAAGACTCTAGAGACTTTGGGGTTTAA
GCAAGTAGATGTTTTAAGATTGCAGCCAGTAACATCGTGACATGTACAACTAGTAAAGAAGGATAAGACAGGTCAAGAAGAAGAGAAGAT
AATCTTTCACCATTGGTCTTAGGTTGATTTTGACTTGAGGTGGATGAAAGGTAACTGTTCAGCTATGGAGGTGGGAGTGGGTTTGGTGCA
AGTTTAATGACAAGGATAGGTTTTTGCTTTCCATTTGGCATGCATGTCTATGTTCAGGTGAATTGGGCCAACTAAATCATTAAGATTGTG
AAGTGGTTCTTTAAAAATCAAGCTATGGTTTTCAGTATTTTGGTTGTAAATTTTGCTTAGCAACAGCTTTTTACCCTGTCGAAACTTAAA
GTCTCTCTTTCGTCTCCCCTGTTGCTAAGGTGCTGCCATGGGGCACACAGGCAGAGTTATTAAGGACGTTCATTCCGTTTCACAGTCGCT
TGATAACAGTATGTTGCTAACAGCTTGCTGTCATATTGGAAACACCCATACTAAAGATATGTAGTATAATATGTTTTCTTTCTACTTAAT
ATGTAACTCATTAGTATGTATATACCTCATGACTTAACATGGACCAAAATAACTGTGTTCCCTGGTGAACAATAATGCAAAATAGACTTC
CCAAAATGTTGATGAAAATCAATGTTGTCGAATTCCTTGTTTGTTAATAAATAAAATAGCTTCCGTAATTAAACGTTTGGCGACATACCT
TCTGTTGAATACCTTTTACAAAATGGAAGTGATCCAAATGTTAAAGACCATGCTGGATGGACACCATTGCATGAAGCTTGCAATCATGGG
CACCTGAAGGTAGTGGAATTATTGCTCCAGCATAAGGCATTGGTGAACACCACCGGGTATCAAAATGACTCACCACTTCACGATGCAGCC
AAGAATGGGCATGTGGATATAGTCAAGCTGTTACTTTCCTATGGAGCCTCCAGAAATGCTGTTAATATATTTGGTCTGCGGCCTGTCGAT
TATACAGATGATGAAAGTATGAAATCGCTATTGCTGCTACCAGAGAAGAATGAATCATCCTCAGCTAGCCACTGCTCAGTAATGAACACT
GGGCAGCGTAGGGATGGACCTCTTGTACTTATAGGCAGTGGGCTGTCTTCAGAACAACAGAAAATGCTCAGTGAGCTTGCAGTAATTCTT
AAGGCTAAAAAATATACTGAGTTTGACAGTACAGTAACTCATGTTGTTGTTCCTGGTGATGCAGTTCAAAGTACCTTGAAGTGTATGCTT
GGGATTCTCAATGGATGCTGGATTCTAAAATTTGAATGGGTAAAAGCATGTCTACGAAGAAAAGTATGTGAACAGGAAGAAAAGTATGAA
ATTCCTGAAGGTCCACGCAGAAGCAGGCTCAACAGAGAACAGCTGTTGCCAAAGCTGTTTGATGGATGCTACTTCTATTTGTGGGGAACC
TTCAAACACCATCCAAAGGACAACCTTATTAAGCTCGTCACTGCAGGTGGGGGCCAGATCCTCAGTAGAAAGCCCAAGCCAGACAGTGAC
GTGACTCAGACCATCAATACAGTCGCATACCATGCGAGACCCGATTCTGATCAGCGCTTCTGCACACAGTATATCATCTATGAAGATTTG
TGTAATTATCACCCAGAGAGGGTTCGGCAGGGCAAAGTCTGGAAGGCTCCTTCGAGCTGGTTTATAGACTGTGTGATGTCCTTTGAGTTG
CTTCCTCTTGACAGCTGAATATTATACCAGATGAACATTTCAAATTGAATTTGCACGGTTTGTGAGAGCCCAGTCATTGTACTGTTTTTA
ATGTTCACATTTTTACAAATAGGTAGAGTCATTCATATTTGTCTTTGAATCAAAAAAAAAAAAAAAGTCTAATGCCAGATTAGGAATTCA
TGTTATGTTTACCATTTAGAAGCTGGGATTGCTTTTAAAGGTTTTTCTTTTTAAAATTGGCATGTTTTTGATTTATCATGTCTTTCTATT
CAGATTATTGGGTATCAAAGATTAATGAGGACACCAGAATCTTGGTTAAATAGACAAGTGGTATCATTACTGTTTGAGTCTTTTAATATT
CTCCATACCTGCCACCAGTGAAAAAACTTGCCTTTTTTTTTTTTTTTTTTTTAGTAAACAGAATATTATCAAACAATTTATTTTGGCTTT
ATTGAAAAAAGAGTATTTGGTCTAAATGTGCCACCATAGGTGTTAAATTCTCCTATCTGCAATTGTCTTTATCCTATATTGTGTTCATTT
CTTTTCTTAATAATTTACTTTGTTGTGTGTTTCTACACTTTCATCCCTGTTTTTTATCTTGTATATCATCAGGAAATTGTGATTTAATCA
TTAACATTGGTTTTTTTGTGTGTGTGGTAAAAATCAACACTAGGCTCATGGTACATATTTTTATTCTGTACATTTGCTTGTAACTATCAA
TTTGTAACTCTGTTTATCTACTACATGTGTATATATACTTAGAGCATTTTCTCTAACACATTTTAATGTTAGTATTTTTTAAAAGGTCTG
ACCAGTCTAGCAAATTGTCAGTCCAACGTCATTACTTTAAATTAAGAAGCAGTCTTCTTCTGGTAAACCTTGTTGGTATTTGTAAAATAA
TTTTGAAGGTCTTAATTTCTTCCTTTGTAAAAGGAAAAGGTTTTTTTTAAAGTTTTTAGGTTGGCATGGAGGCAGAAGTTGGTGATTACT
TGATTTACAACAGATTTTTTCCAGATCATACAAAAGGCCATACAGTAAGTATAGAAGTAGGTATGGGGAGGGCTTACTAATATCAAATAG
GCAAGGCCTTAGTGAGTGGGCAGGATACCACCTGAGAGTGGCCAGATGTGGGGAGGTTACTCTGCTCTGGGTGCTCTCATTCATGAATCG
ACAAGGATACATTAGATTATTTTGAAACATTTTTTTAAGAAGCAGAATTCTTTAATAATTCCTTCCTAGACATTGAATATACTTATAAAA
TTAAAGACTTGGGGAAGGAGACACTGAGAGACTTGCCAGTTTGGTTCCTCATGAACAAAAGAGGACAGTTTGATAACTACCAGAATAGAA
TATCCCTAGTTTTAAAATAGTGAGAATCTCTGAAGTTCATCAACATCTTAAGATGCACTTACTTGAAAGTTTGAGATTCTGTTTATCATT
TGAAAACACATTTTGCTTTAATTCTTTCTTTGACATGTTGTTTTTTCATATCAAGAAATATATGAACAAAATAATAACCTTTTGACCCTG
ACCTTGCTGGGTGAATTAGCTCTGAAACACTCTCTACAACCAGTAATGCATTTGTCCCACATTTCATTCTGATAGAAAATGAACACCATA
GCACCAAACAAAAATCCGAGGCGTTAGATAATGTCTGGATTAAATAATTTAAGACTCTCTAGGATTTTGGTTGTCATTTTTTATTTATAA
CAGACTTTAAGTCACTTTCTGTTGCCTCATAGGTCACATTTTAGACAGGTTTGTGTCTGTTCCTTGCATCTGAATTCCTGATTGTAAAGA
CACCTATGAGGTCTCTTAGTTTTTGTCATTCATTTTCTTGGTTTATCACCCCTCCCTTCTTTTTGTTGTTTTTCCCTGACTGTTAAGCAG
TTTCATCTTTGCTTTTGTTAAATATTTGACAGCAGTTAGTTTGTGTTAAGCTCTTGAAACTTGTGATTGTACTTTCTGTGTAGATATACA
TGTAATTATTTTTTATTTTTCAATCATAGATTCAAGCTTCCTTCTTTTTTACCACAAATCATTAAAGTTATTTGTGTTTCCATATACCTG
TGTCTTGTATAAAATTGGCTTATTCTGTGCTGTTGAATGAGGCTCAACATGACTTGGTGAGGAAGTCTATTAACTAACAAAAGCTTATCT
TTTTTAACATAATGCTTTTTAATTAATTTTGAATAAAAATATTTCTAAAGTGTACTAGATACTTTATTACCTTAGATTATTCCGAATACA
GTATAACTTTGATAGTTTGGAATAGTCATTAAGAAACAATTACACACTGATTGCTTTGTGTCTCTAAAAGTGAGAGGCTGGTAGCTTTTC
CACATTCTCATGGCTATTTTCTAGTTCTACTTGAATTTATAACTGTTTCCCTTTTTCCTTGACAGCTGCCACTTTGTAGCTATTTTTCTG
TCTCTGCTAATACTTTACCATATCTATCTCAATTGTTTTTTCTTTTGACTTGCTGAAAAATAGAAACCAGATGGGAAGTATATTAGCATT
ATGATTGAAATAAGGGTAAATGAGCAATGTGTGAAGGTTTTCACTGACTTCACCTAAAAGATAGTTTAGCTACTTGAATTTTAGTAAATA
GAATTTTTCCTTTATTTCATCGGTCCCCCCACCTTTTTTTTTTTTTGCACCTGCCTTGTAAATTTAATAGTTAAGTGACCTCTGCCTAGA
GGATGATATTTGGGGAGGTTTGATGTTTCCTGTGGGAATAAGACGATTCACAGGTGAGAGTGGGGCCACATTAGCTGTTATTGTTTCCAT
GGGTCAGTGTGGAAAATGCATTAATCATATTCTAAACGTTCATGGGCCTCATTACAGTCACAATTGTCTATTCTGTTTCCTACCCTGAAC
ACATTAAAATGGTAGGAACTAATGCTTGTCTTATTTAATTACTAAAAGCCACCATTTTCTTTGATAGATTGAGCTACAGATTGTAAACTT

>32323_32323_3_GALNTL6-BARD1_GALNTL6_chr4_172735869_ENST00000511251_BARD1_chr2_215634036_ENST00000260947_length(amino acids)=313AA_BP=
MHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDDESMKSLLLLPEKNESSSA
SHCSVMNTGQRRDGPLVLIGSGLSSEQQKMLSELAVILKAKKYTEFDSTVTHVVVPGDAVQSTLKCMLGILNGCWILKFEWVKACLRRKV
CEQEEKYEIPEGPRRSRLNREQLLPKLFDGCYFYLWGTFKHHPKDNLIKLVTAGGGQILSRKPKPDSDVTQTINTVAYHARPDSDQRFCT

--------------------------------------------------------------
>32323_32323_4_GALNTL6-BARD1_GALNTL6_chr4_172735869_ENST00000511251_BARD1_chr2_215634036_ENST00000449967_length(transcript)=3586nt_BP=2598nt
TTTCTCAAGTGAGACACTAGAGAGAGTAGAAAGGGAGGAAGAGATAGGGCGAGAAGAAAAGGAGGGAGGGACAGAGATGAGGACGAGAAA
GAAGAAAAAAGGGAAAGAGAAAATACCGTCTGAAGTCCACAGGCTTATCTATCCCAAGCATGTCTACCCCACGCATGTGGGCATCATATC
CAGGTTGTAACAAAGAGGTGACCATGGCGTTTATTTTTGGCTCCAGACAGGCGGATTCAGCCTGCATTGCATGCATGCATGTCTGTCACC
TCATCTAAGTCCCCATTCCTTCCGGAGTTGTGAGCTCCAGATCCAAGAGTGCCCAGTGCACGGTGCTGGGCACGCTGTCCCTTGGCGAGG
CTGCCACAGGTTCCTGAGTGTGCGGTCAGGGGCGTTGGTGCATTGATACGTTAGGCGGAGGGAGGAGTACCATCTGCCAGAGTCTTATCT
CGAGTCCCACGTTTTCTGGCCATCGCGGAGGAGTGTGCGAGGACAGGTAGCCCTCGCAGTGACAAGGCGCGCGGAGTGCGGTCGTGCAAG
GCGGGGGAGGAGCGGGGTGGCCCTGCCGAATCTTAACCGGGGCCCCGGGTGTTTGCAGACCCAAATAAAGCCGCCTTGGGTCTCCACGGT
GTCCTCCAGAAGCTGCTGCCTGAGAACTCTGAGCCTCAGCTCTGTCTTGCTTCGGGATCCTCTTCCTCCTCCTTCCCCACCCCCTACCTG
GCCTGAACGGCGGAACGCGCGGCTCGGGGGATCCCCTCTCCCTGGGACCGGCCCTGTCCCGGGTCGCCTCCACCTCCCGCAGCCGCCGCG
CCCCGGCTCGCCGCGCTCCCGCCGGCACCATGGAGGAATTCCTGGGACAACCGCCTGCAGCCGGCGACTTTTCCCCAGGAATCTCTGGCC
TGGCGCCCTTTGGGTGAGATGACGGGGTGCTGGCATCCCTGTCGGTCCCAGATTACCCGGAAAAGCCCTGGCAGGTAAAGAGAGGACCCG
CGCAGGCTGGGAGCTCCCACTCCTCCTCCAGCGTCACGCTCGCCCTCCGCCGCTGCCTCGCGTCCGGGTCTGTTTATATAGCGTCTGGAG
GCCGGGAGGCATTGCCCACCCCCGCCAGGCGGCCCGCCCTCCCCTCCTGGGCTCCGGGCTGCCGCACGTGGCAGACACCAGCGACGTCTC
CGCGGAAGGCAGGCGCCGGGGAGTGGGGCGCGGGCGACCGTGTGCAGCCGCGGCGCATCTCCGCCTTCCGCTCCTCCTCGCAGCGCCCTC
GTCCGCTTCCAAGCCCAGCACAGACTTCGGTTTCTCCGCCTCCATCCCCTTTACGAGAAGAGGAGATCAAAAAATATTGCCCTTTAGGTG
CTCGTGATGGTCCTGTGGGTTCGTTCAGTTGCCAGAAAAGAATGGTAACATGAACAGCGGAGCGTGAGAGCGTCACCGGGGGAAGGGACG
AGATTGATGGGCAGAGCGCTCACTTCTCAGAGGATCGCATTCCGAGGACCGCGCGAGGAAGGGACGTCGCGGCGCCACCACTTCCTGGCT
GGACTCCGCTGACATCTGTAGCCTCCTTTCCACCAGGTTCCCGGGGCTCCCAGCCGCTGCCTGCAGAGGAGCGTGTAGACAGCGCGCGAG
GGTCCGGCACTTCGTGGACCTCCATCCGAACCGGAGTTCTGCCCGGATCCCGAGTCCCTGGATCCCGGTGGAGCCCGCCGGCAAGCTGGC
TCCGGAGGGAGTTGAACTTGAGTTCAGGTAAGTGCCACCCAGAGAAAGATCACACAAGGATTGGTAAGGCAGTGATCCTCGCGCGGGGAC
TCGAGAAAGCCGGTGTGGGATCGCCTTGGGTTTTCCCCCAAGTCTTGACAGAGCTGATTATTACAAGACTCTAGAGACTTTGGGGTTTAA
GCAAGTAGATGTTTTAAGATTGCAGCCAGTAACATCGTGACATGTACAACTAGTAAAGAAGGATAAGACAGGTCAAGAAGAAGAGAAGAT
AATCTTTCACCATTGGTCTTAGGTTGATTTTGACTTGAGGTGGATGAAAGGTAACTGTTCAGCTATGGAGGTGGGAGTGGGTTTGGTGCA
AGTTTAATGACAAGGATAGGTTTTTGCTTTCCATTTGGCATGCATGTCTATGTTCAGGTGAATTGGGCCAACTAAATCATTAAGATTGTG
AAGTGGTTCTTTAAAAATCAAGCTATGGTTTTCAGTATTTTGGTTGTAAATTTTGCTTAGCAACAGCTTTTTACCCTGTCGAAACTTAAA
GTCTCTCTTTCGTCTCCCCTGTTGCTAAGGTGCTGCCATGGGGCACACAGGCAGAGTTATTAAGGACGTTCATTCCGTTTCACAGTCGCT
TGATAACAGTATGTTGCTAACAGCTTGCTGTCATATTGGAAACACCCATACTAAAGATATGTAGTATAATATGTTTTCTTTCTACTTAAT
ATGTAACTCATTAGTATGTATATACCTCATGACTTAACATGGACCAAAATAACTGTGTTCCCTGGTGAACAATAATGCAAAATAGACTTC
CCAAAATGTTGATGAAAATCAATGTTGTCGAATTCCTTGTTTGTTAATAAATAAAATAGCTTCCGTAATTAAACGTTTGGCGACATACCT
TCTGTTGAATACCTTTTACAAAATGGAAGTGATCCAAATGTTAAAGACCATGCTGGATGGACACCATTGCATGAAGCTTGCAATCATGGG
CACCTGAAGGTAGTGGAATTATTGCTCCAGCATAAGGCATTGGTGAACACCACCGGGTATCAAAATGACTCACCACTTCACGATGCAGCC
AAGAATGGGCATGTGGATATAGTCAAGCTGTTACTTTCCTATGGAGCCTCCAGAAATGCTGTTAATATATTTGGTCTGCGGCCTGTCGAT
TATACAGATGATGAAAGTATGAAATCGCTATTGCTGCTACCAGAGAAGAATGAATCATCCTCAGCTAGCCACTGCTCAGTAATGAACACT
GGGCAGCGTAGGGATGGACCTCTTGTACTTATAGGCAGTGGGCTGTCTTCAGAACAACAGAAAATGCTCAGTGAGCTTGCAGTAATTCTT
AAGGCTAAAAAATATACTGAGTTTGACAGTACAGTAACTCATGTTGTTGTTCCTGGTGATGCAGTTCAAAGTACCTTGAAGTGTATGCTT
GGGATTCTCAATGGATGCTGGATTCTAAAATTTGAATGGGTAAAAGCATGTCTACGAAGAAAAGTATGTGAACAGGAAGAAAAGTATGAA
ATTCCTGAAGGTCCACGCAGAAGCAGGCTCAACAGAGAACATTGCCAAAGCTGTTTGATGGATGCTACTTCTATTTGTGGGGAACCTTCA
AACACCATCCAAAGGACAACCTTATTAAGCTCGTCACTGCAGGTGGGGGCCAGATCCTCAGTAGAAAGCCCAAGCCAGACAGTGACGTGA
CTCAGACCATCAATACAGTCGCATACCATGCGAGACCCGATTCTGATCAGCGCTTCTGCACACAGTATATCATCTATGAAGATTTGTGTA

>32323_32323_4_GALNTL6-BARD1_GALNTL6_chr4_172735869_ENST00000511251_BARD1_chr2_215634036_ENST00000449967_length(amino acids)=247AA_BP=
MHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDDESMKSLLLLPEKNESSSA
SHCSVMNTGQRRDGPLVLIGSGLSSEQQKMLSELAVILKAKKYTEFDSTVTHVVVPGDAVQSTLKCMLGILNGCWILKFEWVKACLRRKV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for GALNTL6-BARD1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneBARD1chr4:172735869chr2:215634036ENST0000026094731126_119438.0778.0BRCA1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GALNTL6-BARD1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GALNTL6-BARD1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0346153Breast Cancer, Familial11CLINGEN
TgeneC0009405Hereditary Nonpolyposis Colorectal Neoplasms4CLINGEN
TgeneC1112155Hereditary non-polyposis colorectal cancer syndrome4CLINGEN
TgeneC1333990Hereditary Nonpolyposis Colorectal Cancer4CLINGEN
TgeneC1333991Hereditary Non-Polyposis Colon Cancer Type 24CLINGEN
TgeneC2936783Colorectal cancer, hereditary nonpolyposis, type 14CLINGEN
TgeneC0027819Neuroblastoma2CTD_human
TgeneC0677776Hereditary Breast and Ovarian Cancer Syndrome1ORPHANET