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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DRG1-MYO18B (FusionGDB2 ID:HG4733TG84700)

Fusion Gene Summary for DRG1-MYO18B

check button Fusion gene summary
Fusion gene informationFusion gene name: DRG1-MYO18B
Fusion gene ID: hg4733tg84700
HgeneTgene
Gene symbol

DRG1

MYO18B

Gene ID

4733

84700

Gene namedevelopmentally regulated GTP binding protein 1myosin XVIIIB
SynonymsNEDD3KFS4
Cytomap('DRG1')('MYO18B')

22q12.2

22q12.1

Type of geneprotein-codingprotein-coding
Descriptiondevelopmentally-regulated GTP-binding protein 1DRG-1NEDD-3TRAFAC GTPase DRG1neural precursor cell expressed developmentally down-regulated protein 3neural precursor cell expressed, developmentally down-regulated 3translation factor GTPase DRG1unconventional myosin-XVIIIbmyosin 18B
Modification date2020031320200313
UniProtAcc.

Q8IUG5

Ensembl transtripts involved in fusion geneENST00000433341, ENST00000331457, 
Fusion gene scores* DoF score5 X 7 X 5=17511 X 11 X 9=1089
# samples 711
** MAII scorelog2(7/175*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(11/1089*10)=-3.30742852519225
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DRG1 [Title/Abstract] AND MYO18B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDRG1(31799190)-MYO18B(26317224), # samples:3
Anticipated loss of major functional domain due to fusion event.DRG1-MYO18B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DRG1-MYO18B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DRG1-MYO18B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
DRG1-MYO18B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across DRG1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across MYO18B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-33-4532-01ADRG1chr22

31799189

+MYO18Bchr22

26317223

+
ChimerDB4LUSCTCGA-33-4532-01ADRG1chr22

31799190

-MYO18Bchr22

26317224

+
ChimerDB4LUSCTCGA-33-4532-01ADRG1chr22

31799190

+MYO18Bchr22

26317224

+
ChimerDB4LUSCTCGA-33-4532DRG1chr22

31799190

+MYO18Bchr22

26317223

+
ChimerDB4LUSCTCGA-33-4532DRG1chr22

31799190

+MYO18Bchr22

26317224

+


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Fusion Gene ORF analysis for DRG1-MYO18B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000433341ENST00000335473DRG1chr22

31799189

+MYO18Bchr22

26317223

+
3UTR-3CDSENST00000433341ENST00000335473DRG1chr22

31799190

+MYO18Bchr22

26317224

+
3UTR-3CDSENST00000433341ENST00000335473DRG1chr22

31799190

+MYO18Bchr22

26317223

+
3UTR-3CDSENST00000433341ENST00000407587DRG1chr22

31799189

+MYO18Bchr22

26317223

+
3UTR-3CDSENST00000433341ENST00000407587DRG1chr22

31799190

+MYO18Bchr22

26317224

+
3UTR-3CDSENST00000433341ENST00000407587DRG1chr22

31799190

+MYO18Bchr22

26317223

+
3UTR-3CDSENST00000433341ENST00000536101DRG1chr22

31799189

+MYO18Bchr22

26317223

+
3UTR-3CDSENST00000433341ENST00000536101DRG1chr22

31799190

+MYO18Bchr22

26317224

+
3UTR-3CDSENST00000433341ENST00000536101DRG1chr22

31799190

+MYO18Bchr22

26317223

+
3UTR-intronENST00000433341ENST00000536204DRG1chr22

31799189

+MYO18Bchr22

26317223

+
3UTR-intronENST00000433341ENST00000536204DRG1chr22

31799190

+MYO18Bchr22

26317224

+
3UTR-intronENST00000433341ENST00000536204DRG1chr22

31799190

+MYO18Bchr22

26317223

+
5CDS-intronENST00000331457ENST00000536204DRG1chr22

31799189

+MYO18Bchr22

26317223

+
5CDS-intronENST00000331457ENST00000536204DRG1chr22

31799190

+MYO18Bchr22

26317224

+
5CDS-intronENST00000331457ENST00000536204DRG1chr22

31799190

+MYO18Bchr22

26317223

+
In-frameENST00000331457ENST00000335473DRG1chr22

31799189

+MYO18Bchr22

26317223

+
In-frameENST00000331457ENST00000335473DRG1chr22

31799190

+MYO18Bchr22

26317224

+
In-frameENST00000331457ENST00000335473DRG1chr22

31799190

+MYO18Bchr22

26317223

+
In-frameENST00000331457ENST00000407587DRG1chr22

31799189

+MYO18Bchr22

26317223

+
In-frameENST00000331457ENST00000407587DRG1chr22

31799190

+MYO18Bchr22

26317224

+
In-frameENST00000331457ENST00000407587DRG1chr22

31799190

+MYO18Bchr22

26317223

+
In-frameENST00000331457ENST00000536101DRG1chr22

31799189

+MYO18Bchr22

26317223

+
In-frameENST00000331457ENST00000536101DRG1chr22

31799190

+MYO18Bchr22

26317224

+
In-frameENST00000331457ENST00000536101DRG1chr22

31799190

+MYO18Bchr22

26317223

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000331457DRG1chr2231799190+ENST00000536101MYO18Bchr2226317224+2931503892842917
ENST00000331457DRG1chr2231799190+ENST00000335473MYO18Bchr2226317224+3454503892842917
ENST00000331457DRG1chr2231799190+ENST00000407587MYO18Bchr2226317224+3057503892842917
ENST00000331457DRG1chr2231799190+ENST00000536101MYO18Bchr2226317223+2931503892842917
ENST00000331457DRG1chr2231799190+ENST00000335473MYO18Bchr2226317223+3454503892842917
ENST00000331457DRG1chr2231799190+ENST00000407587MYO18Bchr2226317223+3057503892842917
ENST00000331457DRG1chr2231799189+ENST00000536101MYO18Bchr2226317223+2931503892842917
ENST00000331457DRG1chr2231799189+ENST00000335473MYO18Bchr2226317223+3454503892842917
ENST00000331457DRG1chr2231799189+ENST00000407587MYO18Bchr2226317223+3057503892842917

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000331457ENST00000536101DRG1chr2231799190+MYO18Bchr2226317224+0.0094009130.9905991
ENST00000331457ENST00000335473DRG1chr2231799190+MYO18Bchr2226317224+0.0079407090.99205923
ENST00000331457ENST00000407587DRG1chr2231799190+MYO18Bchr2226317224+0.0090471250.99095285
ENST00000331457ENST00000536101DRG1chr2231799190+MYO18Bchr2226317223+0.0094009130.9905991
ENST00000331457ENST00000335473DRG1chr2231799190+MYO18Bchr2226317223+0.0079407090.99205923
ENST00000331457ENST00000407587DRG1chr2231799190+MYO18Bchr2226317223+0.0090471250.99095285
ENST00000331457ENST00000536101DRG1chr2231799189+MYO18Bchr2226317223+0.0094009130.9905991
ENST00000331457ENST00000335473DRG1chr2231799189+MYO18Bchr2226317223+0.0079407090.99205923
ENST00000331457ENST00000407587DRG1chr2231799189+MYO18Bchr2226317223+0.0090471250.99095285

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Fusion Genomic Features for DRG1-MYO18B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DRG1chr2231799190+MYO18Bchr2226317223+6.86E-080.9999999
DRG1chr2231799190+MYO18Bchr2226317223+6.86E-080.9999999
DRG1chr2231799190+MYO18Bchr2226317223+6.86E-080.9999999
DRG1chr2231799190+MYO18Bchr2226317223+6.86E-080.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for DRG1-MYO18B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:31799190/chr22:26317224)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MYO18B

Q8IUG5

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDRG1chr22:31799189chr22:26317223ENST00000331457+3971_78114368.0Nucleotide bindingGTP
HgeneDRG1chr22:31799190chr22:26317223ENST00000331457+3971_78114368.0Nucleotide bindingGTP
HgeneDRG1chr22:31799190chr22:26317224ENST00000331457+3971_78114368.0Nucleotide bindingGTP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDRG1chr22:31799189chr22:26317223ENST00000331457+39290_366114368.0DomainTGS
HgeneDRG1chr22:31799189chr22:26317223ENST00000331457+3965_290114368.0DomainOBG-type G
HgeneDRG1chr22:31799190chr22:26317223ENST00000331457+39290_366114368.0DomainTGS
HgeneDRG1chr22:31799190chr22:26317223ENST00000331457+3965_290114368.0DomainOBG-type G
HgeneDRG1chr22:31799190chr22:26317224ENST00000331457+39290_366114368.0DomainTGS
HgeneDRG1chr22:31799190chr22:26317224ENST00000331457+3965_290114368.0DomainOBG-type G
HgeneDRG1chr22:31799189chr22:26317223ENST00000331457+39117_121114368.0Nucleotide bindingGTP
HgeneDRG1chr22:31799189chr22:26317223ENST00000331457+39248_251114368.0Nucleotide bindingGTP
HgeneDRG1chr22:31799190chr22:26317223ENST00000331457+39117_121114368.0Nucleotide bindingGTP
HgeneDRG1chr22:31799190chr22:26317223ENST00000331457+39248_251114368.0Nucleotide bindingGTP
HgeneDRG1chr22:31799190chr22:26317224ENST00000331457+39117_121114368.0Nucleotide bindingGTP
HgeneDRG1chr22:31799190chr22:26317224ENST00000331457+39248_251114368.0Nucleotide bindingGTP


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Fusion Gene Sequence for DRG1-MYO18B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>24165_24165_1_DRG1-MYO18B_DRG1_chr22_31799189_ENST00000331457_MYO18B_chr22_26317223_ENST00000335473_length(transcript)=3454nt_BP=503nt
CAGCCCCACGCTTTGCGACTCGCGGTGACCCCTACGCGGAACTCTCTCGCGGTAATTCGAAGTACCGCGCCTGCGTGCTGCAGTAGCGCC
TGGTGGCGGTGGCAGTTTGCCCGCGGGTGTGTGAAGGGAGACAGTGTGGAGGCCACAGGGTACTCGCCACGATGAGCAGCACCTTAGCTA
AGATCGCGGAGATAGAAGCAGAGATGGCTCGGACTCAAAAGAACAAGGCCACAGCACACCACTTAGGGCTGCTTAAGGCTCGTCTTGCTA
AGCTTCGTCGAGAACTCATTACTCCAAAGGGTGGTGGTGGTGGAGGTCCAGGAGAAGGTTTTGATGTGGCCAAGACAGGTGATGCTCGAA
TTGGATTTGTTGGTTTTCCATCTGTGGGGAAGTCAACACTGCTTAGTAACCTGGCAGGGGTATATTCTGAGGTGGCAGCCTATGAATTCA
CTACTCTGACCACTGTGCCTGGTGTCATCAGATACAAAGGTGCCAAGATCCAGATTGGCCATCGGGACTTTGATGTGGAGAAGCGACTTC
GGAGAGACCTCAGGAGGACACATGCACTGTTGTCAGACGTGCAGCTCCTTCTGGGCACCATGGAGGATGGCAAGACATCAGTCAGCAAGG
AGGAGCTGGAGAAAGTGCACAGCCAGCTGGAGCAGAGTGAAGCCAAGTGTGAGGAGGCCTTGAAGACGCAGAAGGTGCTCACAGCGGACC
TGGAGAGCATGCACAGCGAGCTGGAGAACATGACGCGGAACAAGAGCCTGGTGGATGAGCAGCTGTACAGGCTGCAGTTTGAGAAGGCGG
ACCTCCTGAAGCGCATCGATGAGGACCAGGATGACCTGAATGAGCTGATGCAGAAGCACAAGGACCTCATTGCTCAGTCTGCTGCTGACA
TTGGGCAGATCCAAGAACTGCAGCTGCAGCTGGAGGAAGCCAAGAAGGAGAAGCACAAGCTACAAGAACAACTGCAGGTGGCTCAGATGC
GCATCGAGTACCTGGAACAGTCCACCGTGGATCGAGCCATCGTCAGCAGGCAGGAGGCGGTCATCTGTGACCTAGAGAACAAGACAGAGT
TCCAGAAGGTGCAGATTAAGAGATTTGAGGTCCTGGTGATCCGGCTTCGGGACAGCCTGATCAAGATGGGGGAGGAGCTTTCACAGGCGG
CCACCTCCGAGTCCCAGCAGCGGGAGAGCAGCCAGTACTACCAGCGGCGCCTGGAAGAGCTGAAGGCCGACATGGAAGAGCTGGTGCAGC
GGGAGGCAGAGGCCAGCCGGCGGTGCATGGAGCTGGAGAAGTACGTGGAGGAACTTGCAGCAGTGAGGCAAACCCTCCAGACAGACCTGG
AGACATCCATTCGGCGGATTGCCGACCTGCAGGCTGCCTTGGAAGAAGTGGCATCCAGTGACAGTGATACTGAGAGTGTCCAGACGGCAG
TGGATTGTGGCAGCAGCGGCCGAAAAGAGATGGATAACGTCTCCATCCTCAGCTCCCAGCCAGAGGGCAGCCTGCAGTCCTGGTTGAGCT
GTACTCTGTCCCTGGCCACAGATACTATGAGGACTCCTTCTCGACAGTCAGCCACCAGCAGCCGCATCCTCAGCCCCAGGATAAACGAAG
AGGCTGGGGACACTGAGAGGACCCAGTCGGCATTGGCACTGAGCAGAGCCCGGTCCACCAATGTCCACAGCAAGACCTCAGGAGACAAGC
CTGTTTCTCCCCACTTTGTCCGCCGGCAAAAGTACTGTCATTTTGGGGACGGCGAAGTGCTTGCCGTCCAGAGAAAGTCCACAGAGAGAT
TAGAACCTGCTTCCTCTCCCCTGGCTTCTCGGAGTACAAATACATCCCCGCTGTCGAGGGAAAAGCTGCCCAGTCCTTCAGCGGCCCTCT
CGGAGTTCGTGGAAGGGCTCCGGAGGAAGAGAGCCCAGAGAGGCCAGGGGTCCACGCTGGGCCTAGAGGACTGGCCCACTCTCCCCATTT
ACCAGACGACTGGGGCCTCCACACTAAGGAGGGGCAGGGCTGGCAGTGACGAGGGAAACCTCTCGCTGAGGGTTGGGGCAAAGTCACCCC
TGGAAATCGAAGGGGCCGCTGGTGGTCTCTTGAGGTCCACCAGCCTCAAATGCATCTCTTCAGACGGTGTTGGGGGCACAACCCTACTCC
CCGAAAAGTCGAAAACCCAATTCAGTTCCTGCGAGTCCCTCTTAGAATCCAGACCGAGCATGGGGAGAAAACTGAGCTCTCCGACCACAC
CCAGGGACATGCTGTTGTCGCCCACACTGCGTCCTCGGAGGCGGTGTCTGGAGTCCTCTGTGGACGATGCGGGCTGTCCAGACCTTGGAA
AGGAGCCGCTTGTTTTCCAGAACCGCCAGTTTGCCCACCTGATGGAGGAACCTCTAGGCAGTGACCCATTCAGCTGGAAACTCCCAAGCC
TCGACTACGAACGCAAGACCAAAGTGGACTTCGATGACTTCCTCCCAGCTATCCGGAAGCCCCAGACACCTACCTCCTTGGCTGGATCAG
CCAAAGGTGGGCAAGACGGTTCACAGCGTTCAAGCATCCACTTTGAAACGGAAGAGGCTAACCGTTCCTTTCTCTCGGGGATCAAGACCA
TTTTGAAGAAGAGCCCGGAGCCCAAGGAGGATCCCGCTCACCTGTCTGACTCGTCCTCATCCTCCGGCTCCATCGTGTCCTTCAAAAGTG
CTGACAGCATCAAAAGTCGACCAGGAATCCCACGACTTGCGGGTGACGGTGGCGAGCGAACGTCCCCCGAGCGGAGAGAGCCAGGGACGG
GGAGGAAAGACGACGATGTTGCGAGCATAATGAAGAAATACCTCCAGAAGTAGGAACCAGTTCAGCCTCCTTGAAGCTGCCCTTGAAGAC
TTCCCGACTCTACAATAACTTGGAGACAGAGAGACTGGCCAGGCCTCCCCGGTGGCCAGAGCCAGCCAGCATGGCCACCCTCAAGAGGCG
AGATGAGCCCACAGAGGCATATCCTGCGGGGATGCTGGGCTCCCAGTGTGGTTGGCCTGAACAAAATAAAGTGTTGACTCCTGGGCATCT
GTGCCTTCTCTATGGCCTTGCTACCTGGGATTCCAGAGAGTTGATGGGGTGCAGATAGGGGTAGGACTGTTAGAATAGAACCAACCCAAA
CTGTGTGTAGTTTGGGGTGTATACTTCTATTTCTCTTCCTACATGTCTACATGCCATGACCTTCCTCCTCCTCTTCACTTGGCCAGTTTC
AGCTCACTTCCTCCAGGAAGTCTTTCCTGATATATCAAACTGAAACAAATGCTCCTCCTCCATGCTCCCTTAATCCCCATGCTTGTCGAT
TATATTCCTTTGCCAATTCATTTCTCTATCCTGTGTATGTATAAGTGTGTACAAGCATTCAAGAAACTGATGAATGATGAATGAATGAAT

>24165_24165_1_DRG1-MYO18B_DRG1_chr22_31799189_ENST00000331457_MYO18B_chr22_26317223_ENST00000335473_length(amino acids)=917AA_BP=137
MVAVAVCPRVCEGRQCGGHRVLATMSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR
IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSK
EELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD
IGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQA
ATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTA
VDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRILSPRINEEAGDTERTQSALALSRARSTNVHSKTSGDK
PVSPHFVRRQKYCHFGDGEVLAVQRKSTERLEPASSPLASRSTNTSPLSREKLPSPSAALSEFVEGLRRKRAQRGQGSTLGLEDWPTLPI
YQTTGASTLRRGRAGSDEGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGGTTLLPEKSKTQFSSCESLLESRPSMGRKLSSPTT
PRDMLLSPTLRPRRRCLESSVDDAGCPDLGKEPLVFQNRQFAHLMEEPLGSDPFSWKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGS
AKGGQDGSQRSSIHFETEEANRSFLSGIKTILKKSPEPKEDPAHLSDSSSSSGSIVSFKSADSIKSRPGIPRLAGDGGERTSPERREPGT

--------------------------------------------------------------
>24165_24165_2_DRG1-MYO18B_DRG1_chr22_31799189_ENST00000331457_MYO18B_chr22_26317223_ENST00000407587_length(transcript)=3057nt_BP=503nt
CAGCCCCACGCTTTGCGACTCGCGGTGACCCCTACGCGGAACTCTCTCGCGGTAATTCGAAGTACCGCGCCTGCGTGCTGCAGTAGCGCC
TGGTGGCGGTGGCAGTTTGCCCGCGGGTGTGTGAAGGGAGACAGTGTGGAGGCCACAGGGTACTCGCCACGATGAGCAGCACCTTAGCTA
AGATCGCGGAGATAGAAGCAGAGATGGCTCGGACTCAAAAGAACAAGGCCACAGCACACCACTTAGGGCTGCTTAAGGCTCGTCTTGCTA
AGCTTCGTCGAGAACTCATTACTCCAAAGGGTGGTGGTGGTGGAGGTCCAGGAGAAGGTTTTGATGTGGCCAAGACAGGTGATGCTCGAA
TTGGATTTGTTGGTTTTCCATCTGTGGGGAAGTCAACACTGCTTAGTAACCTGGCAGGGGTATATTCTGAGGTGGCAGCCTATGAATTCA
CTACTCTGACCACTGTGCCTGGTGTCATCAGATACAAAGGTGCCAAGATCCAGATTGGCCATCGGGACTTTGATGTGGAGAAGCGACTTC
GGAGAGACCTCAGGAGGACACATGCACTGTTGTCAGACGTGCAGCTCCTTCTGGGCACCATGGAGGATGGCAAGACATCAGTCAGCAAGG
AGGAGCTGGAGAAAGTGCACAGCCAGCTGGAGCAGAGTGAAGCCAAGTGTGAGGAGGCCTTGAAGACGCAGAAGGTGCTCACAGCGGACC
TGGAGAGCATGCACAGCGAGCTGGAGAACATGACGCGGAACAAGAGCCTGGTGGATGAGCAGCTGTACAGGCTGCAGTTTGAGAAGGCGG
ACCTCCTGAAGCGCATCGATGAGGACCAGGATGACCTGAATGAGCTGATGCAGAAGCACAAGGACCTCATTGCTCAGTCTGCTGCTGACA
TTGGGCAGATCCAAGAACTGCAGCTGCAGCTGGAGGAAGCCAAGAAGGAGAAGCACAAGCTACAAGAACAACTGCAGGTGGCTCAGATGC
GCATCGAGTACCTGGAACAGTCCACCGTGGATCGAGCCATCGTCAGCAGGCAGGAGGCGGTCATCTGTGACCTAGAGAACAAGACAGAGT
TCCAGAAGGTGCAGATTAAGAGATTTGAGGTCCTGGTGATCCGGCTTCGGGACAGCCTGATCAAGATGGGGGAGGAGCTTTCACAGGCGG
CCACCTCCGAGTCCCAGCAGCGGGAGAGCAGCCAGTACTACCAGCGGCGCCTGGAAGAGCTGAAGGCCGACATGGAAGAGCTGGTGCAGC
GGGAGGCAGAGGCCAGCCGGCGGTGCATGGAGCTGGAGAAGTACGTGGAGGAACTTGCAGCAGTGAGGCAAACCCTCCAGACAGACCTGG
AGACATCCATTCGGCGGATTGCCGACCTGCAGGCTGCCTTGGAAGAAGTGGCATCCAGTGACAGTGATACTGAGAGTGTCCAGACGGCAG
TGGATTGTGGCAGCAGCGGCCGAAAAGAGATGGATAACGTCTCCATCCTCAGCTCCCAGCCAGAGGGCAGCCTGCAGTCCTGGTTGAGCT
GTACTCTGTCCCTGGCCACAGATACTATGAGGACTCCTTCTCGACAGTCAGCCACCAGCAGCCGCATCCTCAGCCCCAGGATAAACGAAG
AGGCTGGGGACACTGAGAGGACCCAGTCGGCATTGGCACTGAGCAGAGCCCGGTCCACCAATGTCCACAGCAAGACCTCAGGAGACAAGC
CTGTTTCTCCCCACTTTGTCCGCCGGCAAAAGTACTGTCATTTTGGGGACGGCGAAGTGCTTGCCGTCCAGAGAAAGTCCACAGAGAGAT
TAGAACCTGCTTCCTCTCCCCTGGCTTCTCGGAGTACAAATACATCCCCGCTGTCGAGGGAAAAGCTGCCCAGTCCTTCAGCGGCCCTCT
CGGAGTTCGTGGAAGGGCTCCGGAGGAAGAGAGCCCAGAGAGGCCAGGGGTCCACGCTGGGCCTAGAGGACTGGCCCACTCTCCCCATTT
ACCAGACGACTGGGGCCTCCACACTAAGGAGGGGCAGGGCTGGCAGTGACGAGGGAAACCTCTCGCTGAGGGTTGGGGCAAAGTCACCCC
TGGAAATCGAAGGGGCCGCTGGTGGTCTCTTGAGGTCCACCAGCCTCAAATGCATCTCTTCAGACGGTGTTGGGGGCACAACCCTACTCC
CCGAAAAGTCGAAAACCCAATTCAGTTCCTGCGAGTCCCTCTTAGAATCCAGACCGAGCATGGGGAGAAAACTGAGCTCTCCGACCACAC
CCAGGGACATGCTGTTGTCGCCCACACTGCGTCCTCGGAGGCGGTGTCTGGAGTCCTCTGTGGACGATGCGGGCTGTCCAGACCTTGGAA
AGGAGCCGCTTGTTTTCCAGAACCGCCAGTTTGCCCACCTGATGGAGGAACCTCTAGGCAGTGACCCATTCAGCTGGAAACTCCCAAGCC
TCGACTACGAACGCAAGACCAAAGTGGACTTCGATGACTTCCTCCCAGCTATCCGGAAGCCCCAGACACCTACCTCCTTGGCTGGATCAG
CCAAAGGTGGGCAAGACGGTTCACAGCGTTCAAGCATCCACTTTGAAACGGAAGAGGCTAACCGTTCCTTTCTCTCGGGGATCAAGACCA
TTTTGAAGAAGAGCCCGGAGCCCAAGGAGGATCCCGCTCACCTGTCTGACTCGTCCTCATCCTCCGGCTCCATCGTGTCCTTCAAAAGTG
CTGACAGCATCAAAAGTCGACCAGGAATCCCACGACTTGCGGGTGACGGTGGCGAGCGAACGTCCCCCGAGCGGAGAGAGCCAGGGACGG
GGAGGAAAGACGACGATGTTGCGAGCATAATGAAGAAATACCTCCAGAAGTAGGAACCAGTTCAGCCTCCTTGAAGCTGCCCTTGAAGAC
TTCCCGACTCTACAATAACTTGGAGACAGAGAGACTGGCCAGGCCTCCCCGGTGGCCAGAGCCAGCCAGCATGGCCACCCTCAAGAGGCG

>24165_24165_2_DRG1-MYO18B_DRG1_chr22_31799189_ENST00000331457_MYO18B_chr22_26317223_ENST00000407587_length(amino acids)=917AA_BP=137
MVAVAVCPRVCEGRQCGGHRVLATMSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR
IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSK
EELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD
IGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQA
ATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTA
VDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRILSPRINEEAGDTERTQSALALSRARSTNVHSKTSGDK
PVSPHFVRRQKYCHFGDGEVLAVQRKSTERLEPASSPLASRSTNTSPLSREKLPSPSAALSEFVEGLRRKRAQRGQGSTLGLEDWPTLPI
YQTTGASTLRRGRAGSDEGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGGTTLLPEKSKTQFSSCESLLESRPSMGRKLSSPTT
PRDMLLSPTLRPRRRCLESSVDDAGCPDLGKEPLVFQNRQFAHLMEEPLGSDPFSWKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGS
AKGGQDGSQRSSIHFETEEANRSFLSGIKTILKKSPEPKEDPAHLSDSSSSSGSIVSFKSADSIKSRPGIPRLAGDGGERTSPERREPGT

--------------------------------------------------------------
>24165_24165_3_DRG1-MYO18B_DRG1_chr22_31799189_ENST00000331457_MYO18B_chr22_26317223_ENST00000536101_length(transcript)=2931nt_BP=503nt
CAGCCCCACGCTTTGCGACTCGCGGTGACCCCTACGCGGAACTCTCTCGCGGTAATTCGAAGTACCGCGCCTGCGTGCTGCAGTAGCGCC
TGGTGGCGGTGGCAGTTTGCCCGCGGGTGTGTGAAGGGAGACAGTGTGGAGGCCACAGGGTACTCGCCACGATGAGCAGCACCTTAGCTA
AGATCGCGGAGATAGAAGCAGAGATGGCTCGGACTCAAAAGAACAAGGCCACAGCACACCACTTAGGGCTGCTTAAGGCTCGTCTTGCTA
AGCTTCGTCGAGAACTCATTACTCCAAAGGGTGGTGGTGGTGGAGGTCCAGGAGAAGGTTTTGATGTGGCCAAGACAGGTGATGCTCGAA
TTGGATTTGTTGGTTTTCCATCTGTGGGGAAGTCAACACTGCTTAGTAACCTGGCAGGGGTATATTCTGAGGTGGCAGCCTATGAATTCA
CTACTCTGACCACTGTGCCTGGTGTCATCAGATACAAAGGTGCCAAGATCCAGATTGGCCATCGGGACTTTGATGTGGAGAAGCGACTTC
GGAGAGACCTCAGGAGGACACATGCACTGTTGTCAGACGTGCAGCTCCTTCTGGGCACCATGGAGGATGGCAAGACATCAGTCAGCAAGG
AGGAGCTGGAGAAAGTGCACAGCCAGCTGGAGCAGAGTGAAGCCAAGTGTGAGGAGGCCTTGAAGACGCAGAAGGTGCTCACAGCGGACC
TGGAGAGCATGCACAGCGAGCTGGAGAACATGACGCGGAACAAGAGCCTGGTGGATGAGCAGCTGTACAGGCTGCAGTTTGAGAAGGCGG
ACCTCCTGAAGCGCATCGATGAGGACCAGGATGACCTGAATGAGCTGATGCAGAAGCACAAGGACCTCATTGCTCAGTCTGCTGCTGACA
TTGGGCAGATCCAAGAACTGCAGCTGCAGCTGGAGGAAGCCAAGAAGGAGAAGCACAAGCTACAAGAACAACTGCAGGTGGCTCAGATGC
GCATCGAGTACCTGGAACAGTCCACCGTGGATCGAGCCATCGTCAGCAGGCAGGAGGCGGTCATCTGTGACCTAGAGAACAAGACAGAGT
TCCAGAAGGTGCAGATTAAGAGATTTGAGGTCCTGGTGATCCGGCTTCGGGACAGCCTGATCAAGATGGGGGAGGAGCTTTCACAGGCGG
CCACCTCCGAGTCCCAGCAGCGGGAGAGCAGCCAGTACTACCAGCGGCGCCTGGAAGAGCTGAAGGCCGACATGGAAGAGCTGGTGCAGC
GGGAGGCAGAGGCCAGCCGGCGGTGCATGGAGCTGGAGAAGTACGTGGAGGAACTTGCAGCAGTGAGGCAAACCCTCCAGACAGACCTGG
AGACATCCATTCGGCGGATTGCCGACCTGCAGGCTGCCTTGGAAGAAGTGGCATCCAGTGACAGTGATACTGAGAGTGTCCAGACGGCAG
TGGATTGTGGCAGCAGCGGCCGAAAAGAGATGGATAACGTCTCCATCCTCAGCTCCCAGCCAGAGGGCAGCCTGCAGTCCTGGTTGAGCT
GTACTCTGTCCCTGGCCACAGATACTATGAGGACTCCTTCTCGACAGTCAGCCACCAGCAGCCGCATCCTCAGCCCCAGGATAAACGAAG
AGGCTGGGGACACTGAGAGGACCCAGTCGGCATTGGCACTGAGCAGAGCCCGGTCCACCAATGTCCACAGCAAGACCTCAGGAGACAAGC
CTGTTTCTCCCCACTTTGTCCGCCGGCAAAAGTACTGTCATTTTGGGGACGGCGAAGTGCTTGCCGTCCAGAGAAAGTCCACAGAGAGAT
TAGAACCTGCTTCCTCTCCCCTGGCTTCTCGGAGTACAAATACATCCCCGCTGTCGAGGGAAAAGCTGCCCAGTCCTTCAGCGGCCCTCT
CGGAGTTCGTGGAAGGGCTCCGGAGGAAGAGAGCCCAGAGAGGCCAGGGGTCCACGCTGGGCCTAGAGGACTGGCCCACTCTCCCCATTT
ACCAGACGACTGGGGCCTCCACACTAAGGAGGGGCAGGGCTGGCAGTGACGAGGGAAACCTCTCGCTGAGGGTTGGGGCAAAGTCACCCC
TGGAAATCGAAGGGGCCGCTGGTGGTCTCTTGAGGTCCACCAGCCTCAAATGCATCTCTTCAGACGGTGTTGGGGGCACAACCCTACTCC
CCGAAAAGTCGAAAACCCAATTCAGTTCCTGCGAGTCCCTCTTAGAATCCAGACCGAGCATGGGGAGAAAACTGAGCTCTCCGACCACAC
CCAGGGACATGCTGTTGTCGCCCACACTGCGTCCTCGGAGGCGGTGTCTGGAGTCCTCTGTGGACGATGCGGGCTGTCCAGACCTTGGAA
AGGAGCCGCTTGTTTTCCAGAACCGCCAGTTTGCCCACCTGATGGAGGAACCTCTAGGCAGTGACCCATTCAGCTGGAAACTCCCAAGCC
TCGACTACGAACGCAAGACCAAAGTGGACTTCGATGACTTCCTCCCAGCTATCCGGAAGCCCCAGACACCTACCTCCTTGGCTGGATCAG
CCAAAGGTGGGCAAGACGGTTCACAGCGTTCAAGCATCCACTTTGAAACGGAAGAGGCTAACCGTTCCTTTCTCTCGGGGATCAAGACCA
TTTTGAAGAAGAGCCCGGAGCCCAAGGAGGATCCCGCTCACCTGTCTGACTCGTCCTCATCCTCCGGCTCCATCGTGTCCTTCAAAAGTG
CTGACAGCATCAAAAGTCGACCAGGAATCCCACGACTTGCGGGTGACGGTGGCGAGCGAACGTCCCCCGAGCGGAGAGAGCCAGGGACGG
GGAGGAAAGACGACGATGTTGCGAGCATAATGAAGAAATACCTCCAGAAGTAGGAACCAGTTCAGGTAAAAGCAACAGGCTGGGGCTATT

>24165_24165_3_DRG1-MYO18B_DRG1_chr22_31799189_ENST00000331457_MYO18B_chr22_26317223_ENST00000536101_length(amino acids)=917AA_BP=137
MVAVAVCPRVCEGRQCGGHRVLATMSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR
IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSK
EELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD
IGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQA
ATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTA
VDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRILSPRINEEAGDTERTQSALALSRARSTNVHSKTSGDK
PVSPHFVRRQKYCHFGDGEVLAVQRKSTERLEPASSPLASRSTNTSPLSREKLPSPSAALSEFVEGLRRKRAQRGQGSTLGLEDWPTLPI
YQTTGASTLRRGRAGSDEGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGGTTLLPEKSKTQFSSCESLLESRPSMGRKLSSPTT
PRDMLLSPTLRPRRRCLESSVDDAGCPDLGKEPLVFQNRQFAHLMEEPLGSDPFSWKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGS
AKGGQDGSQRSSIHFETEEANRSFLSGIKTILKKSPEPKEDPAHLSDSSSSSGSIVSFKSADSIKSRPGIPRLAGDGGERTSPERREPGT

--------------------------------------------------------------
>24165_24165_4_DRG1-MYO18B_DRG1_chr22_31799190_ENST00000331457_MYO18B_chr22_26317223_ENST00000335473_length(transcript)=3454nt_BP=503nt
CAGCCCCACGCTTTGCGACTCGCGGTGACCCCTACGCGGAACTCTCTCGCGGTAATTCGAAGTACCGCGCCTGCGTGCTGCAGTAGCGCC
TGGTGGCGGTGGCAGTTTGCCCGCGGGTGTGTGAAGGGAGACAGTGTGGAGGCCACAGGGTACTCGCCACGATGAGCAGCACCTTAGCTA
AGATCGCGGAGATAGAAGCAGAGATGGCTCGGACTCAAAAGAACAAGGCCACAGCACACCACTTAGGGCTGCTTAAGGCTCGTCTTGCTA
AGCTTCGTCGAGAACTCATTACTCCAAAGGGTGGTGGTGGTGGAGGTCCAGGAGAAGGTTTTGATGTGGCCAAGACAGGTGATGCTCGAA
TTGGATTTGTTGGTTTTCCATCTGTGGGGAAGTCAACACTGCTTAGTAACCTGGCAGGGGTATATTCTGAGGTGGCAGCCTATGAATTCA
CTACTCTGACCACTGTGCCTGGTGTCATCAGATACAAAGGTGCCAAGATCCAGATTGGCCATCGGGACTTTGATGTGGAGAAGCGACTTC
GGAGAGACCTCAGGAGGACACATGCACTGTTGTCAGACGTGCAGCTCCTTCTGGGCACCATGGAGGATGGCAAGACATCAGTCAGCAAGG
AGGAGCTGGAGAAAGTGCACAGCCAGCTGGAGCAGAGTGAAGCCAAGTGTGAGGAGGCCTTGAAGACGCAGAAGGTGCTCACAGCGGACC
TGGAGAGCATGCACAGCGAGCTGGAGAACATGACGCGGAACAAGAGCCTGGTGGATGAGCAGCTGTACAGGCTGCAGTTTGAGAAGGCGG
ACCTCCTGAAGCGCATCGATGAGGACCAGGATGACCTGAATGAGCTGATGCAGAAGCACAAGGACCTCATTGCTCAGTCTGCTGCTGACA
TTGGGCAGATCCAAGAACTGCAGCTGCAGCTGGAGGAAGCCAAGAAGGAGAAGCACAAGCTACAAGAACAACTGCAGGTGGCTCAGATGC
GCATCGAGTACCTGGAACAGTCCACCGTGGATCGAGCCATCGTCAGCAGGCAGGAGGCGGTCATCTGTGACCTAGAGAACAAGACAGAGT
TCCAGAAGGTGCAGATTAAGAGATTTGAGGTCCTGGTGATCCGGCTTCGGGACAGCCTGATCAAGATGGGGGAGGAGCTTTCACAGGCGG
CCACCTCCGAGTCCCAGCAGCGGGAGAGCAGCCAGTACTACCAGCGGCGCCTGGAAGAGCTGAAGGCCGACATGGAAGAGCTGGTGCAGC
GGGAGGCAGAGGCCAGCCGGCGGTGCATGGAGCTGGAGAAGTACGTGGAGGAACTTGCAGCAGTGAGGCAAACCCTCCAGACAGACCTGG
AGACATCCATTCGGCGGATTGCCGACCTGCAGGCTGCCTTGGAAGAAGTGGCATCCAGTGACAGTGATACTGAGAGTGTCCAGACGGCAG
TGGATTGTGGCAGCAGCGGCCGAAAAGAGATGGATAACGTCTCCATCCTCAGCTCCCAGCCAGAGGGCAGCCTGCAGTCCTGGTTGAGCT
GTACTCTGTCCCTGGCCACAGATACTATGAGGACTCCTTCTCGACAGTCAGCCACCAGCAGCCGCATCCTCAGCCCCAGGATAAACGAAG
AGGCTGGGGACACTGAGAGGACCCAGTCGGCATTGGCACTGAGCAGAGCCCGGTCCACCAATGTCCACAGCAAGACCTCAGGAGACAAGC
CTGTTTCTCCCCACTTTGTCCGCCGGCAAAAGTACTGTCATTTTGGGGACGGCGAAGTGCTTGCCGTCCAGAGAAAGTCCACAGAGAGAT
TAGAACCTGCTTCCTCTCCCCTGGCTTCTCGGAGTACAAATACATCCCCGCTGTCGAGGGAAAAGCTGCCCAGTCCTTCAGCGGCCCTCT
CGGAGTTCGTGGAAGGGCTCCGGAGGAAGAGAGCCCAGAGAGGCCAGGGGTCCACGCTGGGCCTAGAGGACTGGCCCACTCTCCCCATTT
ACCAGACGACTGGGGCCTCCACACTAAGGAGGGGCAGGGCTGGCAGTGACGAGGGAAACCTCTCGCTGAGGGTTGGGGCAAAGTCACCCC
TGGAAATCGAAGGGGCCGCTGGTGGTCTCTTGAGGTCCACCAGCCTCAAATGCATCTCTTCAGACGGTGTTGGGGGCACAACCCTACTCC
CCGAAAAGTCGAAAACCCAATTCAGTTCCTGCGAGTCCCTCTTAGAATCCAGACCGAGCATGGGGAGAAAACTGAGCTCTCCGACCACAC
CCAGGGACATGCTGTTGTCGCCCACACTGCGTCCTCGGAGGCGGTGTCTGGAGTCCTCTGTGGACGATGCGGGCTGTCCAGACCTTGGAA
AGGAGCCGCTTGTTTTCCAGAACCGCCAGTTTGCCCACCTGATGGAGGAACCTCTAGGCAGTGACCCATTCAGCTGGAAACTCCCAAGCC
TCGACTACGAACGCAAGACCAAAGTGGACTTCGATGACTTCCTCCCAGCTATCCGGAAGCCCCAGACACCTACCTCCTTGGCTGGATCAG
CCAAAGGTGGGCAAGACGGTTCACAGCGTTCAAGCATCCACTTTGAAACGGAAGAGGCTAACCGTTCCTTTCTCTCGGGGATCAAGACCA
TTTTGAAGAAGAGCCCGGAGCCCAAGGAGGATCCCGCTCACCTGTCTGACTCGTCCTCATCCTCCGGCTCCATCGTGTCCTTCAAAAGTG
CTGACAGCATCAAAAGTCGACCAGGAATCCCACGACTTGCGGGTGACGGTGGCGAGCGAACGTCCCCCGAGCGGAGAGAGCCAGGGACGG
GGAGGAAAGACGACGATGTTGCGAGCATAATGAAGAAATACCTCCAGAAGTAGGAACCAGTTCAGCCTCCTTGAAGCTGCCCTTGAAGAC
TTCCCGACTCTACAATAACTTGGAGACAGAGAGACTGGCCAGGCCTCCCCGGTGGCCAGAGCCAGCCAGCATGGCCACCCTCAAGAGGCG
AGATGAGCCCACAGAGGCATATCCTGCGGGGATGCTGGGCTCCCAGTGTGGTTGGCCTGAACAAAATAAAGTGTTGACTCCTGGGCATCT
GTGCCTTCTCTATGGCCTTGCTACCTGGGATTCCAGAGAGTTGATGGGGTGCAGATAGGGGTAGGACTGTTAGAATAGAACCAACCCAAA
CTGTGTGTAGTTTGGGGTGTATACTTCTATTTCTCTTCCTACATGTCTACATGCCATGACCTTCCTCCTCCTCTTCACTTGGCCAGTTTC
AGCTCACTTCCTCCAGGAAGTCTTTCCTGATATATCAAACTGAAACAAATGCTCCTCCTCCATGCTCCCTTAATCCCCATGCTTGTCGAT
TATATTCCTTTGCCAATTCATTTCTCTATCCTGTGTATGTATAAGTGTGTACAAGCATTCAAGAAACTGATGAATGATGAATGAATGAAT

>24165_24165_4_DRG1-MYO18B_DRG1_chr22_31799190_ENST00000331457_MYO18B_chr22_26317223_ENST00000335473_length(amino acids)=917AA_BP=137
MVAVAVCPRVCEGRQCGGHRVLATMSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR
IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSK
EELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD
IGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQA
ATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTA
VDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRILSPRINEEAGDTERTQSALALSRARSTNVHSKTSGDK
PVSPHFVRRQKYCHFGDGEVLAVQRKSTERLEPASSPLASRSTNTSPLSREKLPSPSAALSEFVEGLRRKRAQRGQGSTLGLEDWPTLPI
YQTTGASTLRRGRAGSDEGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGGTTLLPEKSKTQFSSCESLLESRPSMGRKLSSPTT
PRDMLLSPTLRPRRRCLESSVDDAGCPDLGKEPLVFQNRQFAHLMEEPLGSDPFSWKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGS
AKGGQDGSQRSSIHFETEEANRSFLSGIKTILKKSPEPKEDPAHLSDSSSSSGSIVSFKSADSIKSRPGIPRLAGDGGERTSPERREPGT

--------------------------------------------------------------
>24165_24165_5_DRG1-MYO18B_DRG1_chr22_31799190_ENST00000331457_MYO18B_chr22_26317223_ENST00000407587_length(transcript)=3057nt_BP=503nt
CAGCCCCACGCTTTGCGACTCGCGGTGACCCCTACGCGGAACTCTCTCGCGGTAATTCGAAGTACCGCGCCTGCGTGCTGCAGTAGCGCC
TGGTGGCGGTGGCAGTTTGCCCGCGGGTGTGTGAAGGGAGACAGTGTGGAGGCCACAGGGTACTCGCCACGATGAGCAGCACCTTAGCTA
AGATCGCGGAGATAGAAGCAGAGATGGCTCGGACTCAAAAGAACAAGGCCACAGCACACCACTTAGGGCTGCTTAAGGCTCGTCTTGCTA
AGCTTCGTCGAGAACTCATTACTCCAAAGGGTGGTGGTGGTGGAGGTCCAGGAGAAGGTTTTGATGTGGCCAAGACAGGTGATGCTCGAA
TTGGATTTGTTGGTTTTCCATCTGTGGGGAAGTCAACACTGCTTAGTAACCTGGCAGGGGTATATTCTGAGGTGGCAGCCTATGAATTCA
CTACTCTGACCACTGTGCCTGGTGTCATCAGATACAAAGGTGCCAAGATCCAGATTGGCCATCGGGACTTTGATGTGGAGAAGCGACTTC
GGAGAGACCTCAGGAGGACACATGCACTGTTGTCAGACGTGCAGCTCCTTCTGGGCACCATGGAGGATGGCAAGACATCAGTCAGCAAGG
AGGAGCTGGAGAAAGTGCACAGCCAGCTGGAGCAGAGTGAAGCCAAGTGTGAGGAGGCCTTGAAGACGCAGAAGGTGCTCACAGCGGACC
TGGAGAGCATGCACAGCGAGCTGGAGAACATGACGCGGAACAAGAGCCTGGTGGATGAGCAGCTGTACAGGCTGCAGTTTGAGAAGGCGG
ACCTCCTGAAGCGCATCGATGAGGACCAGGATGACCTGAATGAGCTGATGCAGAAGCACAAGGACCTCATTGCTCAGTCTGCTGCTGACA
TTGGGCAGATCCAAGAACTGCAGCTGCAGCTGGAGGAAGCCAAGAAGGAGAAGCACAAGCTACAAGAACAACTGCAGGTGGCTCAGATGC
GCATCGAGTACCTGGAACAGTCCACCGTGGATCGAGCCATCGTCAGCAGGCAGGAGGCGGTCATCTGTGACCTAGAGAACAAGACAGAGT
TCCAGAAGGTGCAGATTAAGAGATTTGAGGTCCTGGTGATCCGGCTTCGGGACAGCCTGATCAAGATGGGGGAGGAGCTTTCACAGGCGG
CCACCTCCGAGTCCCAGCAGCGGGAGAGCAGCCAGTACTACCAGCGGCGCCTGGAAGAGCTGAAGGCCGACATGGAAGAGCTGGTGCAGC
GGGAGGCAGAGGCCAGCCGGCGGTGCATGGAGCTGGAGAAGTACGTGGAGGAACTTGCAGCAGTGAGGCAAACCCTCCAGACAGACCTGG
AGACATCCATTCGGCGGATTGCCGACCTGCAGGCTGCCTTGGAAGAAGTGGCATCCAGTGACAGTGATACTGAGAGTGTCCAGACGGCAG
TGGATTGTGGCAGCAGCGGCCGAAAAGAGATGGATAACGTCTCCATCCTCAGCTCCCAGCCAGAGGGCAGCCTGCAGTCCTGGTTGAGCT
GTACTCTGTCCCTGGCCACAGATACTATGAGGACTCCTTCTCGACAGTCAGCCACCAGCAGCCGCATCCTCAGCCCCAGGATAAACGAAG
AGGCTGGGGACACTGAGAGGACCCAGTCGGCATTGGCACTGAGCAGAGCCCGGTCCACCAATGTCCACAGCAAGACCTCAGGAGACAAGC
CTGTTTCTCCCCACTTTGTCCGCCGGCAAAAGTACTGTCATTTTGGGGACGGCGAAGTGCTTGCCGTCCAGAGAAAGTCCACAGAGAGAT
TAGAACCTGCTTCCTCTCCCCTGGCTTCTCGGAGTACAAATACATCCCCGCTGTCGAGGGAAAAGCTGCCCAGTCCTTCAGCGGCCCTCT
CGGAGTTCGTGGAAGGGCTCCGGAGGAAGAGAGCCCAGAGAGGCCAGGGGTCCACGCTGGGCCTAGAGGACTGGCCCACTCTCCCCATTT
ACCAGACGACTGGGGCCTCCACACTAAGGAGGGGCAGGGCTGGCAGTGACGAGGGAAACCTCTCGCTGAGGGTTGGGGCAAAGTCACCCC
TGGAAATCGAAGGGGCCGCTGGTGGTCTCTTGAGGTCCACCAGCCTCAAATGCATCTCTTCAGACGGTGTTGGGGGCACAACCCTACTCC
CCGAAAAGTCGAAAACCCAATTCAGTTCCTGCGAGTCCCTCTTAGAATCCAGACCGAGCATGGGGAGAAAACTGAGCTCTCCGACCACAC
CCAGGGACATGCTGTTGTCGCCCACACTGCGTCCTCGGAGGCGGTGTCTGGAGTCCTCTGTGGACGATGCGGGCTGTCCAGACCTTGGAA
AGGAGCCGCTTGTTTTCCAGAACCGCCAGTTTGCCCACCTGATGGAGGAACCTCTAGGCAGTGACCCATTCAGCTGGAAACTCCCAAGCC
TCGACTACGAACGCAAGACCAAAGTGGACTTCGATGACTTCCTCCCAGCTATCCGGAAGCCCCAGACACCTACCTCCTTGGCTGGATCAG
CCAAAGGTGGGCAAGACGGTTCACAGCGTTCAAGCATCCACTTTGAAACGGAAGAGGCTAACCGTTCCTTTCTCTCGGGGATCAAGACCA
TTTTGAAGAAGAGCCCGGAGCCCAAGGAGGATCCCGCTCACCTGTCTGACTCGTCCTCATCCTCCGGCTCCATCGTGTCCTTCAAAAGTG
CTGACAGCATCAAAAGTCGACCAGGAATCCCACGACTTGCGGGTGACGGTGGCGAGCGAACGTCCCCCGAGCGGAGAGAGCCAGGGACGG
GGAGGAAAGACGACGATGTTGCGAGCATAATGAAGAAATACCTCCAGAAGTAGGAACCAGTTCAGCCTCCTTGAAGCTGCCCTTGAAGAC
TTCCCGACTCTACAATAACTTGGAGACAGAGAGACTGGCCAGGCCTCCCCGGTGGCCAGAGCCAGCCAGCATGGCCACCCTCAAGAGGCG

>24165_24165_5_DRG1-MYO18B_DRG1_chr22_31799190_ENST00000331457_MYO18B_chr22_26317223_ENST00000407587_length(amino acids)=917AA_BP=137
MVAVAVCPRVCEGRQCGGHRVLATMSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR
IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSK
EELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD
IGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQA
ATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTA
VDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRILSPRINEEAGDTERTQSALALSRARSTNVHSKTSGDK
PVSPHFVRRQKYCHFGDGEVLAVQRKSTERLEPASSPLASRSTNTSPLSREKLPSPSAALSEFVEGLRRKRAQRGQGSTLGLEDWPTLPI
YQTTGASTLRRGRAGSDEGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGGTTLLPEKSKTQFSSCESLLESRPSMGRKLSSPTT
PRDMLLSPTLRPRRRCLESSVDDAGCPDLGKEPLVFQNRQFAHLMEEPLGSDPFSWKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGS
AKGGQDGSQRSSIHFETEEANRSFLSGIKTILKKSPEPKEDPAHLSDSSSSSGSIVSFKSADSIKSRPGIPRLAGDGGERTSPERREPGT

--------------------------------------------------------------
>24165_24165_6_DRG1-MYO18B_DRG1_chr22_31799190_ENST00000331457_MYO18B_chr22_26317223_ENST00000536101_length(transcript)=2931nt_BP=503nt
CAGCCCCACGCTTTGCGACTCGCGGTGACCCCTACGCGGAACTCTCTCGCGGTAATTCGAAGTACCGCGCCTGCGTGCTGCAGTAGCGCC
TGGTGGCGGTGGCAGTTTGCCCGCGGGTGTGTGAAGGGAGACAGTGTGGAGGCCACAGGGTACTCGCCACGATGAGCAGCACCTTAGCTA
AGATCGCGGAGATAGAAGCAGAGATGGCTCGGACTCAAAAGAACAAGGCCACAGCACACCACTTAGGGCTGCTTAAGGCTCGTCTTGCTA
AGCTTCGTCGAGAACTCATTACTCCAAAGGGTGGTGGTGGTGGAGGTCCAGGAGAAGGTTTTGATGTGGCCAAGACAGGTGATGCTCGAA
TTGGATTTGTTGGTTTTCCATCTGTGGGGAAGTCAACACTGCTTAGTAACCTGGCAGGGGTATATTCTGAGGTGGCAGCCTATGAATTCA
CTACTCTGACCACTGTGCCTGGTGTCATCAGATACAAAGGTGCCAAGATCCAGATTGGCCATCGGGACTTTGATGTGGAGAAGCGACTTC
GGAGAGACCTCAGGAGGACACATGCACTGTTGTCAGACGTGCAGCTCCTTCTGGGCACCATGGAGGATGGCAAGACATCAGTCAGCAAGG
AGGAGCTGGAGAAAGTGCACAGCCAGCTGGAGCAGAGTGAAGCCAAGTGTGAGGAGGCCTTGAAGACGCAGAAGGTGCTCACAGCGGACC
TGGAGAGCATGCACAGCGAGCTGGAGAACATGACGCGGAACAAGAGCCTGGTGGATGAGCAGCTGTACAGGCTGCAGTTTGAGAAGGCGG
ACCTCCTGAAGCGCATCGATGAGGACCAGGATGACCTGAATGAGCTGATGCAGAAGCACAAGGACCTCATTGCTCAGTCTGCTGCTGACA
TTGGGCAGATCCAAGAACTGCAGCTGCAGCTGGAGGAAGCCAAGAAGGAGAAGCACAAGCTACAAGAACAACTGCAGGTGGCTCAGATGC
GCATCGAGTACCTGGAACAGTCCACCGTGGATCGAGCCATCGTCAGCAGGCAGGAGGCGGTCATCTGTGACCTAGAGAACAAGACAGAGT
TCCAGAAGGTGCAGATTAAGAGATTTGAGGTCCTGGTGATCCGGCTTCGGGACAGCCTGATCAAGATGGGGGAGGAGCTTTCACAGGCGG
CCACCTCCGAGTCCCAGCAGCGGGAGAGCAGCCAGTACTACCAGCGGCGCCTGGAAGAGCTGAAGGCCGACATGGAAGAGCTGGTGCAGC
GGGAGGCAGAGGCCAGCCGGCGGTGCATGGAGCTGGAGAAGTACGTGGAGGAACTTGCAGCAGTGAGGCAAACCCTCCAGACAGACCTGG
AGACATCCATTCGGCGGATTGCCGACCTGCAGGCTGCCTTGGAAGAAGTGGCATCCAGTGACAGTGATACTGAGAGTGTCCAGACGGCAG
TGGATTGTGGCAGCAGCGGCCGAAAAGAGATGGATAACGTCTCCATCCTCAGCTCCCAGCCAGAGGGCAGCCTGCAGTCCTGGTTGAGCT
GTACTCTGTCCCTGGCCACAGATACTATGAGGACTCCTTCTCGACAGTCAGCCACCAGCAGCCGCATCCTCAGCCCCAGGATAAACGAAG
AGGCTGGGGACACTGAGAGGACCCAGTCGGCATTGGCACTGAGCAGAGCCCGGTCCACCAATGTCCACAGCAAGACCTCAGGAGACAAGC
CTGTTTCTCCCCACTTTGTCCGCCGGCAAAAGTACTGTCATTTTGGGGACGGCGAAGTGCTTGCCGTCCAGAGAAAGTCCACAGAGAGAT
TAGAACCTGCTTCCTCTCCCCTGGCTTCTCGGAGTACAAATACATCCCCGCTGTCGAGGGAAAAGCTGCCCAGTCCTTCAGCGGCCCTCT
CGGAGTTCGTGGAAGGGCTCCGGAGGAAGAGAGCCCAGAGAGGCCAGGGGTCCACGCTGGGCCTAGAGGACTGGCCCACTCTCCCCATTT
ACCAGACGACTGGGGCCTCCACACTAAGGAGGGGCAGGGCTGGCAGTGACGAGGGAAACCTCTCGCTGAGGGTTGGGGCAAAGTCACCCC
TGGAAATCGAAGGGGCCGCTGGTGGTCTCTTGAGGTCCACCAGCCTCAAATGCATCTCTTCAGACGGTGTTGGGGGCACAACCCTACTCC
CCGAAAAGTCGAAAACCCAATTCAGTTCCTGCGAGTCCCTCTTAGAATCCAGACCGAGCATGGGGAGAAAACTGAGCTCTCCGACCACAC
CCAGGGACATGCTGTTGTCGCCCACACTGCGTCCTCGGAGGCGGTGTCTGGAGTCCTCTGTGGACGATGCGGGCTGTCCAGACCTTGGAA
AGGAGCCGCTTGTTTTCCAGAACCGCCAGTTTGCCCACCTGATGGAGGAACCTCTAGGCAGTGACCCATTCAGCTGGAAACTCCCAAGCC
TCGACTACGAACGCAAGACCAAAGTGGACTTCGATGACTTCCTCCCAGCTATCCGGAAGCCCCAGACACCTACCTCCTTGGCTGGATCAG
CCAAAGGTGGGCAAGACGGTTCACAGCGTTCAAGCATCCACTTTGAAACGGAAGAGGCTAACCGTTCCTTTCTCTCGGGGATCAAGACCA
TTTTGAAGAAGAGCCCGGAGCCCAAGGAGGATCCCGCTCACCTGTCTGACTCGTCCTCATCCTCCGGCTCCATCGTGTCCTTCAAAAGTG
CTGACAGCATCAAAAGTCGACCAGGAATCCCACGACTTGCGGGTGACGGTGGCGAGCGAACGTCCCCCGAGCGGAGAGAGCCAGGGACGG
GGAGGAAAGACGACGATGTTGCGAGCATAATGAAGAAATACCTCCAGAAGTAGGAACCAGTTCAGGTAAAAGCAACAGGCTGGGGCTATT

>24165_24165_6_DRG1-MYO18B_DRG1_chr22_31799190_ENST00000331457_MYO18B_chr22_26317223_ENST00000536101_length(amino acids)=917AA_BP=137
MVAVAVCPRVCEGRQCGGHRVLATMSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR
IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSK
EELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD
IGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQA
ATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTA
VDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRILSPRINEEAGDTERTQSALALSRARSTNVHSKTSGDK
PVSPHFVRRQKYCHFGDGEVLAVQRKSTERLEPASSPLASRSTNTSPLSREKLPSPSAALSEFVEGLRRKRAQRGQGSTLGLEDWPTLPI
YQTTGASTLRRGRAGSDEGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGGTTLLPEKSKTQFSSCESLLESRPSMGRKLSSPTT
PRDMLLSPTLRPRRRCLESSVDDAGCPDLGKEPLVFQNRQFAHLMEEPLGSDPFSWKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGS
AKGGQDGSQRSSIHFETEEANRSFLSGIKTILKKSPEPKEDPAHLSDSSSSSGSIVSFKSADSIKSRPGIPRLAGDGGERTSPERREPGT

--------------------------------------------------------------
>24165_24165_7_DRG1-MYO18B_DRG1_chr22_31799190_ENST00000331457_MYO18B_chr22_26317224_ENST00000335473_length(transcript)=3454nt_BP=503nt
CAGCCCCACGCTTTGCGACTCGCGGTGACCCCTACGCGGAACTCTCTCGCGGTAATTCGAAGTACCGCGCCTGCGTGCTGCAGTAGCGCC
TGGTGGCGGTGGCAGTTTGCCCGCGGGTGTGTGAAGGGAGACAGTGTGGAGGCCACAGGGTACTCGCCACGATGAGCAGCACCTTAGCTA
AGATCGCGGAGATAGAAGCAGAGATGGCTCGGACTCAAAAGAACAAGGCCACAGCACACCACTTAGGGCTGCTTAAGGCTCGTCTTGCTA
AGCTTCGTCGAGAACTCATTACTCCAAAGGGTGGTGGTGGTGGAGGTCCAGGAGAAGGTTTTGATGTGGCCAAGACAGGTGATGCTCGAA
TTGGATTTGTTGGTTTTCCATCTGTGGGGAAGTCAACACTGCTTAGTAACCTGGCAGGGGTATATTCTGAGGTGGCAGCCTATGAATTCA
CTACTCTGACCACTGTGCCTGGTGTCATCAGATACAAAGGTGCCAAGATCCAGATTGGCCATCGGGACTTTGATGTGGAGAAGCGACTTC
GGAGAGACCTCAGGAGGACACATGCACTGTTGTCAGACGTGCAGCTCCTTCTGGGCACCATGGAGGATGGCAAGACATCAGTCAGCAAGG
AGGAGCTGGAGAAAGTGCACAGCCAGCTGGAGCAGAGTGAAGCCAAGTGTGAGGAGGCCTTGAAGACGCAGAAGGTGCTCACAGCGGACC
TGGAGAGCATGCACAGCGAGCTGGAGAACATGACGCGGAACAAGAGCCTGGTGGATGAGCAGCTGTACAGGCTGCAGTTTGAGAAGGCGG
ACCTCCTGAAGCGCATCGATGAGGACCAGGATGACCTGAATGAGCTGATGCAGAAGCACAAGGACCTCATTGCTCAGTCTGCTGCTGACA
TTGGGCAGATCCAAGAACTGCAGCTGCAGCTGGAGGAAGCCAAGAAGGAGAAGCACAAGCTACAAGAACAACTGCAGGTGGCTCAGATGC
GCATCGAGTACCTGGAACAGTCCACCGTGGATCGAGCCATCGTCAGCAGGCAGGAGGCGGTCATCTGTGACCTAGAGAACAAGACAGAGT
TCCAGAAGGTGCAGATTAAGAGATTTGAGGTCCTGGTGATCCGGCTTCGGGACAGCCTGATCAAGATGGGGGAGGAGCTTTCACAGGCGG
CCACCTCCGAGTCCCAGCAGCGGGAGAGCAGCCAGTACTACCAGCGGCGCCTGGAAGAGCTGAAGGCCGACATGGAAGAGCTGGTGCAGC
GGGAGGCAGAGGCCAGCCGGCGGTGCATGGAGCTGGAGAAGTACGTGGAGGAACTTGCAGCAGTGAGGCAAACCCTCCAGACAGACCTGG
AGACATCCATTCGGCGGATTGCCGACCTGCAGGCTGCCTTGGAAGAAGTGGCATCCAGTGACAGTGATACTGAGAGTGTCCAGACGGCAG
TGGATTGTGGCAGCAGCGGCCGAAAAGAGATGGATAACGTCTCCATCCTCAGCTCCCAGCCAGAGGGCAGCCTGCAGTCCTGGTTGAGCT
GTACTCTGTCCCTGGCCACAGATACTATGAGGACTCCTTCTCGACAGTCAGCCACCAGCAGCCGCATCCTCAGCCCCAGGATAAACGAAG
AGGCTGGGGACACTGAGAGGACCCAGTCGGCATTGGCACTGAGCAGAGCCCGGTCCACCAATGTCCACAGCAAGACCTCAGGAGACAAGC
CTGTTTCTCCCCACTTTGTCCGCCGGCAAAAGTACTGTCATTTTGGGGACGGCGAAGTGCTTGCCGTCCAGAGAAAGTCCACAGAGAGAT
TAGAACCTGCTTCCTCTCCCCTGGCTTCTCGGAGTACAAATACATCCCCGCTGTCGAGGGAAAAGCTGCCCAGTCCTTCAGCGGCCCTCT
CGGAGTTCGTGGAAGGGCTCCGGAGGAAGAGAGCCCAGAGAGGCCAGGGGTCCACGCTGGGCCTAGAGGACTGGCCCACTCTCCCCATTT
ACCAGACGACTGGGGCCTCCACACTAAGGAGGGGCAGGGCTGGCAGTGACGAGGGAAACCTCTCGCTGAGGGTTGGGGCAAAGTCACCCC
TGGAAATCGAAGGGGCCGCTGGTGGTCTCTTGAGGTCCACCAGCCTCAAATGCATCTCTTCAGACGGTGTTGGGGGCACAACCCTACTCC
CCGAAAAGTCGAAAACCCAATTCAGTTCCTGCGAGTCCCTCTTAGAATCCAGACCGAGCATGGGGAGAAAACTGAGCTCTCCGACCACAC
CCAGGGACATGCTGTTGTCGCCCACACTGCGTCCTCGGAGGCGGTGTCTGGAGTCCTCTGTGGACGATGCGGGCTGTCCAGACCTTGGAA
AGGAGCCGCTTGTTTTCCAGAACCGCCAGTTTGCCCACCTGATGGAGGAACCTCTAGGCAGTGACCCATTCAGCTGGAAACTCCCAAGCC
TCGACTACGAACGCAAGACCAAAGTGGACTTCGATGACTTCCTCCCAGCTATCCGGAAGCCCCAGACACCTACCTCCTTGGCTGGATCAG
CCAAAGGTGGGCAAGACGGTTCACAGCGTTCAAGCATCCACTTTGAAACGGAAGAGGCTAACCGTTCCTTTCTCTCGGGGATCAAGACCA
TTTTGAAGAAGAGCCCGGAGCCCAAGGAGGATCCCGCTCACCTGTCTGACTCGTCCTCATCCTCCGGCTCCATCGTGTCCTTCAAAAGTG
CTGACAGCATCAAAAGTCGACCAGGAATCCCACGACTTGCGGGTGACGGTGGCGAGCGAACGTCCCCCGAGCGGAGAGAGCCAGGGACGG
GGAGGAAAGACGACGATGTTGCGAGCATAATGAAGAAATACCTCCAGAAGTAGGAACCAGTTCAGCCTCCTTGAAGCTGCCCTTGAAGAC
TTCCCGACTCTACAATAACTTGGAGACAGAGAGACTGGCCAGGCCTCCCCGGTGGCCAGAGCCAGCCAGCATGGCCACCCTCAAGAGGCG
AGATGAGCCCACAGAGGCATATCCTGCGGGGATGCTGGGCTCCCAGTGTGGTTGGCCTGAACAAAATAAAGTGTTGACTCCTGGGCATCT
GTGCCTTCTCTATGGCCTTGCTACCTGGGATTCCAGAGAGTTGATGGGGTGCAGATAGGGGTAGGACTGTTAGAATAGAACCAACCCAAA
CTGTGTGTAGTTTGGGGTGTATACTTCTATTTCTCTTCCTACATGTCTACATGCCATGACCTTCCTCCTCCTCTTCACTTGGCCAGTTTC
AGCTCACTTCCTCCAGGAAGTCTTTCCTGATATATCAAACTGAAACAAATGCTCCTCCTCCATGCTCCCTTAATCCCCATGCTTGTCGAT
TATATTCCTTTGCCAATTCATTTCTCTATCCTGTGTATGTATAAGTGTGTACAAGCATTCAAGAAACTGATGAATGATGAATGAATGAAT

>24165_24165_7_DRG1-MYO18B_DRG1_chr22_31799190_ENST00000331457_MYO18B_chr22_26317224_ENST00000335473_length(amino acids)=917AA_BP=137
MVAVAVCPRVCEGRQCGGHRVLATMSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR
IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSK
EELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD
IGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQA
ATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTA
VDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRILSPRINEEAGDTERTQSALALSRARSTNVHSKTSGDK
PVSPHFVRRQKYCHFGDGEVLAVQRKSTERLEPASSPLASRSTNTSPLSREKLPSPSAALSEFVEGLRRKRAQRGQGSTLGLEDWPTLPI
YQTTGASTLRRGRAGSDEGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGGTTLLPEKSKTQFSSCESLLESRPSMGRKLSSPTT
PRDMLLSPTLRPRRRCLESSVDDAGCPDLGKEPLVFQNRQFAHLMEEPLGSDPFSWKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGS
AKGGQDGSQRSSIHFETEEANRSFLSGIKTILKKSPEPKEDPAHLSDSSSSSGSIVSFKSADSIKSRPGIPRLAGDGGERTSPERREPGT

--------------------------------------------------------------
>24165_24165_8_DRG1-MYO18B_DRG1_chr22_31799190_ENST00000331457_MYO18B_chr22_26317224_ENST00000407587_length(transcript)=3057nt_BP=503nt
CAGCCCCACGCTTTGCGACTCGCGGTGACCCCTACGCGGAACTCTCTCGCGGTAATTCGAAGTACCGCGCCTGCGTGCTGCAGTAGCGCC
TGGTGGCGGTGGCAGTTTGCCCGCGGGTGTGTGAAGGGAGACAGTGTGGAGGCCACAGGGTACTCGCCACGATGAGCAGCACCTTAGCTA
AGATCGCGGAGATAGAAGCAGAGATGGCTCGGACTCAAAAGAACAAGGCCACAGCACACCACTTAGGGCTGCTTAAGGCTCGTCTTGCTA
AGCTTCGTCGAGAACTCATTACTCCAAAGGGTGGTGGTGGTGGAGGTCCAGGAGAAGGTTTTGATGTGGCCAAGACAGGTGATGCTCGAA
TTGGATTTGTTGGTTTTCCATCTGTGGGGAAGTCAACACTGCTTAGTAACCTGGCAGGGGTATATTCTGAGGTGGCAGCCTATGAATTCA
CTACTCTGACCACTGTGCCTGGTGTCATCAGATACAAAGGTGCCAAGATCCAGATTGGCCATCGGGACTTTGATGTGGAGAAGCGACTTC
GGAGAGACCTCAGGAGGACACATGCACTGTTGTCAGACGTGCAGCTCCTTCTGGGCACCATGGAGGATGGCAAGACATCAGTCAGCAAGG
AGGAGCTGGAGAAAGTGCACAGCCAGCTGGAGCAGAGTGAAGCCAAGTGTGAGGAGGCCTTGAAGACGCAGAAGGTGCTCACAGCGGACC
TGGAGAGCATGCACAGCGAGCTGGAGAACATGACGCGGAACAAGAGCCTGGTGGATGAGCAGCTGTACAGGCTGCAGTTTGAGAAGGCGG
ACCTCCTGAAGCGCATCGATGAGGACCAGGATGACCTGAATGAGCTGATGCAGAAGCACAAGGACCTCATTGCTCAGTCTGCTGCTGACA
TTGGGCAGATCCAAGAACTGCAGCTGCAGCTGGAGGAAGCCAAGAAGGAGAAGCACAAGCTACAAGAACAACTGCAGGTGGCTCAGATGC
GCATCGAGTACCTGGAACAGTCCACCGTGGATCGAGCCATCGTCAGCAGGCAGGAGGCGGTCATCTGTGACCTAGAGAACAAGACAGAGT
TCCAGAAGGTGCAGATTAAGAGATTTGAGGTCCTGGTGATCCGGCTTCGGGACAGCCTGATCAAGATGGGGGAGGAGCTTTCACAGGCGG
CCACCTCCGAGTCCCAGCAGCGGGAGAGCAGCCAGTACTACCAGCGGCGCCTGGAAGAGCTGAAGGCCGACATGGAAGAGCTGGTGCAGC
GGGAGGCAGAGGCCAGCCGGCGGTGCATGGAGCTGGAGAAGTACGTGGAGGAACTTGCAGCAGTGAGGCAAACCCTCCAGACAGACCTGG
AGACATCCATTCGGCGGATTGCCGACCTGCAGGCTGCCTTGGAAGAAGTGGCATCCAGTGACAGTGATACTGAGAGTGTCCAGACGGCAG
TGGATTGTGGCAGCAGCGGCCGAAAAGAGATGGATAACGTCTCCATCCTCAGCTCCCAGCCAGAGGGCAGCCTGCAGTCCTGGTTGAGCT
GTACTCTGTCCCTGGCCACAGATACTATGAGGACTCCTTCTCGACAGTCAGCCACCAGCAGCCGCATCCTCAGCCCCAGGATAAACGAAG
AGGCTGGGGACACTGAGAGGACCCAGTCGGCATTGGCACTGAGCAGAGCCCGGTCCACCAATGTCCACAGCAAGACCTCAGGAGACAAGC
CTGTTTCTCCCCACTTTGTCCGCCGGCAAAAGTACTGTCATTTTGGGGACGGCGAAGTGCTTGCCGTCCAGAGAAAGTCCACAGAGAGAT
TAGAACCTGCTTCCTCTCCCCTGGCTTCTCGGAGTACAAATACATCCCCGCTGTCGAGGGAAAAGCTGCCCAGTCCTTCAGCGGCCCTCT
CGGAGTTCGTGGAAGGGCTCCGGAGGAAGAGAGCCCAGAGAGGCCAGGGGTCCACGCTGGGCCTAGAGGACTGGCCCACTCTCCCCATTT
ACCAGACGACTGGGGCCTCCACACTAAGGAGGGGCAGGGCTGGCAGTGACGAGGGAAACCTCTCGCTGAGGGTTGGGGCAAAGTCACCCC
TGGAAATCGAAGGGGCCGCTGGTGGTCTCTTGAGGTCCACCAGCCTCAAATGCATCTCTTCAGACGGTGTTGGGGGCACAACCCTACTCC
CCGAAAAGTCGAAAACCCAATTCAGTTCCTGCGAGTCCCTCTTAGAATCCAGACCGAGCATGGGGAGAAAACTGAGCTCTCCGACCACAC
CCAGGGACATGCTGTTGTCGCCCACACTGCGTCCTCGGAGGCGGTGTCTGGAGTCCTCTGTGGACGATGCGGGCTGTCCAGACCTTGGAA
AGGAGCCGCTTGTTTTCCAGAACCGCCAGTTTGCCCACCTGATGGAGGAACCTCTAGGCAGTGACCCATTCAGCTGGAAACTCCCAAGCC
TCGACTACGAACGCAAGACCAAAGTGGACTTCGATGACTTCCTCCCAGCTATCCGGAAGCCCCAGACACCTACCTCCTTGGCTGGATCAG
CCAAAGGTGGGCAAGACGGTTCACAGCGTTCAAGCATCCACTTTGAAACGGAAGAGGCTAACCGTTCCTTTCTCTCGGGGATCAAGACCA
TTTTGAAGAAGAGCCCGGAGCCCAAGGAGGATCCCGCTCACCTGTCTGACTCGTCCTCATCCTCCGGCTCCATCGTGTCCTTCAAAAGTG
CTGACAGCATCAAAAGTCGACCAGGAATCCCACGACTTGCGGGTGACGGTGGCGAGCGAACGTCCCCCGAGCGGAGAGAGCCAGGGACGG
GGAGGAAAGACGACGATGTTGCGAGCATAATGAAGAAATACCTCCAGAAGTAGGAACCAGTTCAGCCTCCTTGAAGCTGCCCTTGAAGAC
TTCCCGACTCTACAATAACTTGGAGACAGAGAGACTGGCCAGGCCTCCCCGGTGGCCAGAGCCAGCCAGCATGGCCACCCTCAAGAGGCG

>24165_24165_8_DRG1-MYO18B_DRG1_chr22_31799190_ENST00000331457_MYO18B_chr22_26317224_ENST00000407587_length(amino acids)=917AA_BP=137
MVAVAVCPRVCEGRQCGGHRVLATMSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR
IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSK
EELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD
IGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQA
ATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTA
VDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRILSPRINEEAGDTERTQSALALSRARSTNVHSKTSGDK
PVSPHFVRRQKYCHFGDGEVLAVQRKSTERLEPASSPLASRSTNTSPLSREKLPSPSAALSEFVEGLRRKRAQRGQGSTLGLEDWPTLPI
YQTTGASTLRRGRAGSDEGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGGTTLLPEKSKTQFSSCESLLESRPSMGRKLSSPTT
PRDMLLSPTLRPRRRCLESSVDDAGCPDLGKEPLVFQNRQFAHLMEEPLGSDPFSWKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGS
AKGGQDGSQRSSIHFETEEANRSFLSGIKTILKKSPEPKEDPAHLSDSSSSSGSIVSFKSADSIKSRPGIPRLAGDGGERTSPERREPGT

--------------------------------------------------------------
>24165_24165_9_DRG1-MYO18B_DRG1_chr22_31799190_ENST00000331457_MYO18B_chr22_26317224_ENST00000536101_length(transcript)=2931nt_BP=503nt
CAGCCCCACGCTTTGCGACTCGCGGTGACCCCTACGCGGAACTCTCTCGCGGTAATTCGAAGTACCGCGCCTGCGTGCTGCAGTAGCGCC
TGGTGGCGGTGGCAGTTTGCCCGCGGGTGTGTGAAGGGAGACAGTGTGGAGGCCACAGGGTACTCGCCACGATGAGCAGCACCTTAGCTA
AGATCGCGGAGATAGAAGCAGAGATGGCTCGGACTCAAAAGAACAAGGCCACAGCACACCACTTAGGGCTGCTTAAGGCTCGTCTTGCTA
AGCTTCGTCGAGAACTCATTACTCCAAAGGGTGGTGGTGGTGGAGGTCCAGGAGAAGGTTTTGATGTGGCCAAGACAGGTGATGCTCGAA
TTGGATTTGTTGGTTTTCCATCTGTGGGGAAGTCAACACTGCTTAGTAACCTGGCAGGGGTATATTCTGAGGTGGCAGCCTATGAATTCA
CTACTCTGACCACTGTGCCTGGTGTCATCAGATACAAAGGTGCCAAGATCCAGATTGGCCATCGGGACTTTGATGTGGAGAAGCGACTTC
GGAGAGACCTCAGGAGGACACATGCACTGTTGTCAGACGTGCAGCTCCTTCTGGGCACCATGGAGGATGGCAAGACATCAGTCAGCAAGG
AGGAGCTGGAGAAAGTGCACAGCCAGCTGGAGCAGAGTGAAGCCAAGTGTGAGGAGGCCTTGAAGACGCAGAAGGTGCTCACAGCGGACC
TGGAGAGCATGCACAGCGAGCTGGAGAACATGACGCGGAACAAGAGCCTGGTGGATGAGCAGCTGTACAGGCTGCAGTTTGAGAAGGCGG
ACCTCCTGAAGCGCATCGATGAGGACCAGGATGACCTGAATGAGCTGATGCAGAAGCACAAGGACCTCATTGCTCAGTCTGCTGCTGACA
TTGGGCAGATCCAAGAACTGCAGCTGCAGCTGGAGGAAGCCAAGAAGGAGAAGCACAAGCTACAAGAACAACTGCAGGTGGCTCAGATGC
GCATCGAGTACCTGGAACAGTCCACCGTGGATCGAGCCATCGTCAGCAGGCAGGAGGCGGTCATCTGTGACCTAGAGAACAAGACAGAGT
TCCAGAAGGTGCAGATTAAGAGATTTGAGGTCCTGGTGATCCGGCTTCGGGACAGCCTGATCAAGATGGGGGAGGAGCTTTCACAGGCGG
CCACCTCCGAGTCCCAGCAGCGGGAGAGCAGCCAGTACTACCAGCGGCGCCTGGAAGAGCTGAAGGCCGACATGGAAGAGCTGGTGCAGC
GGGAGGCAGAGGCCAGCCGGCGGTGCATGGAGCTGGAGAAGTACGTGGAGGAACTTGCAGCAGTGAGGCAAACCCTCCAGACAGACCTGG
AGACATCCATTCGGCGGATTGCCGACCTGCAGGCTGCCTTGGAAGAAGTGGCATCCAGTGACAGTGATACTGAGAGTGTCCAGACGGCAG
TGGATTGTGGCAGCAGCGGCCGAAAAGAGATGGATAACGTCTCCATCCTCAGCTCCCAGCCAGAGGGCAGCCTGCAGTCCTGGTTGAGCT
GTACTCTGTCCCTGGCCACAGATACTATGAGGACTCCTTCTCGACAGTCAGCCACCAGCAGCCGCATCCTCAGCCCCAGGATAAACGAAG
AGGCTGGGGACACTGAGAGGACCCAGTCGGCATTGGCACTGAGCAGAGCCCGGTCCACCAATGTCCACAGCAAGACCTCAGGAGACAAGC
CTGTTTCTCCCCACTTTGTCCGCCGGCAAAAGTACTGTCATTTTGGGGACGGCGAAGTGCTTGCCGTCCAGAGAAAGTCCACAGAGAGAT
TAGAACCTGCTTCCTCTCCCCTGGCTTCTCGGAGTACAAATACATCCCCGCTGTCGAGGGAAAAGCTGCCCAGTCCTTCAGCGGCCCTCT
CGGAGTTCGTGGAAGGGCTCCGGAGGAAGAGAGCCCAGAGAGGCCAGGGGTCCACGCTGGGCCTAGAGGACTGGCCCACTCTCCCCATTT
ACCAGACGACTGGGGCCTCCACACTAAGGAGGGGCAGGGCTGGCAGTGACGAGGGAAACCTCTCGCTGAGGGTTGGGGCAAAGTCACCCC
TGGAAATCGAAGGGGCCGCTGGTGGTCTCTTGAGGTCCACCAGCCTCAAATGCATCTCTTCAGACGGTGTTGGGGGCACAACCCTACTCC
CCGAAAAGTCGAAAACCCAATTCAGTTCCTGCGAGTCCCTCTTAGAATCCAGACCGAGCATGGGGAGAAAACTGAGCTCTCCGACCACAC
CCAGGGACATGCTGTTGTCGCCCACACTGCGTCCTCGGAGGCGGTGTCTGGAGTCCTCTGTGGACGATGCGGGCTGTCCAGACCTTGGAA
AGGAGCCGCTTGTTTTCCAGAACCGCCAGTTTGCCCACCTGATGGAGGAACCTCTAGGCAGTGACCCATTCAGCTGGAAACTCCCAAGCC
TCGACTACGAACGCAAGACCAAAGTGGACTTCGATGACTTCCTCCCAGCTATCCGGAAGCCCCAGACACCTACCTCCTTGGCTGGATCAG
CCAAAGGTGGGCAAGACGGTTCACAGCGTTCAAGCATCCACTTTGAAACGGAAGAGGCTAACCGTTCCTTTCTCTCGGGGATCAAGACCA
TTTTGAAGAAGAGCCCGGAGCCCAAGGAGGATCCCGCTCACCTGTCTGACTCGTCCTCATCCTCCGGCTCCATCGTGTCCTTCAAAAGTG
CTGACAGCATCAAAAGTCGACCAGGAATCCCACGACTTGCGGGTGACGGTGGCGAGCGAACGTCCCCCGAGCGGAGAGAGCCAGGGACGG
GGAGGAAAGACGACGATGTTGCGAGCATAATGAAGAAATACCTCCAGAAGTAGGAACCAGTTCAGGTAAAAGCAACAGGCTGGGGCTATT

>24165_24165_9_DRG1-MYO18B_DRG1_chr22_31799190_ENST00000331457_MYO18B_chr22_26317224_ENST00000536101_length(amino acids)=917AA_BP=137
MVAVAVCPRVCEGRQCGGHRVLATMSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR
IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSK
EELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD
IGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQA
ATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTA
VDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRILSPRINEEAGDTERTQSALALSRARSTNVHSKTSGDK
PVSPHFVRRQKYCHFGDGEVLAVQRKSTERLEPASSPLASRSTNTSPLSREKLPSPSAALSEFVEGLRRKRAQRGQGSTLGLEDWPTLPI
YQTTGASTLRRGRAGSDEGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGGTTLLPEKSKTQFSSCESLLESRPSMGRKLSSPTT
PRDMLLSPTLRPRRRCLESSVDDAGCPDLGKEPLVFQNRQFAHLMEEPLGSDPFSWKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGS
AKGGQDGSQRSSIHFETEEANRSFLSGIKTILKKSPEPKEDPAHLSDSSSSSGSIVSFKSADSIKSRPGIPRLAGDGGERTSPERREPGT

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Fusion Gene PPI Analysis for DRG1-MYO18B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DRG1-MYO18B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DRG1-MYO18B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC4225285KLIPPEL-FEIL SYNDROME 4, AUTOSOMAL RECESSIVE, WITH NEMALINE MYOPATHY AND FACIAL DYSMORPHISM5CLINGEN;CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneC0004238Atrial Fibrillation2CTD_human
TgeneC0235480Paroxysmal atrial fibrillation2CTD_human
TgeneC2585653Persistent atrial fibrillation2CTD_human
TgeneC3468561familial atrial fibrillation2CTD_human
TgeneC0025500Mesothelioma1CTD_human